GREMLIN Database
O52001 - Uncharacterized protein
UniProt: O52001 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 661 (557)
Sequences: 501 (495)
Seq/√Len: 21.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
340_D382_Q6.5841.00
267_F338_S4.9101.00
241_A244_T4.7841.00
321_K382_Q4.5121.00
100_L117_V3.9071.00
356_A409_V3.8601.00
378_G384_Q3.7121.00
357_I391_V3.4251.00
384_Q387_Q3.3611.00
257_E260_P3.2551.00
82_W98_L3.0320.99
143_I160_V2.9730.99
321_K340_D2.9610.99
286_R293_T2.8190.99
91_D101_E2.7780.99
413_L419_Y2.7260.99
210_W213_L2.6520.98
118_P155_P2.6460.98
419_Y424_A2.6130.98
257_E265_K2.6100.98
148_Q156_S2.4650.97
306_D309_R2.4570.97
413_L417_K2.4530.97
247_E250_E2.4430.97
150_G158_Y2.4310.97
209_L213_L2.3520.97
419_Y422_G2.3280.96
252_T283_E2.3030.96
151_V157_V2.3020.96
151_V156_S2.2830.96
304_I307_L2.2730.96
148_Q158_Y2.2650.96
246_S307_L2.2650.96
321_K339_V2.2600.96
477_G482_E2.1680.95
417_K424_A2.1500.94
300_D304_I2.1410.94
378_G387_Q2.1200.94
150_G156_S2.1140.94
150_G157_V2.1090.94
119_N158_Y2.0880.93
337_A345_Y2.0790.93
595_L599_E2.0680.93
412_A419_Y2.0590.93
316_K343_L2.0350.93
413_L424_A2.0350.93
209_L212_P2.0310.92
153_E157_V2.0280.92
592_I595_L2.0280.92
416_Y419_Y2.0060.92
263_T286_R1.9890.92
594_P597_R1.9830.92
338_S384_Q1.9730.91
303_I307_L1.9670.91
495_L526_S1.9620.91
150_G179_D1.9580.91
248_A338_S1.9550.91
307_L312_Y1.9510.91
119_N156_S1.9100.90
477_G481_Q1.8920.89
260_P265_K1.8860.89
254_A257_E1.8800.89
151_V158_Y1.8550.88
119_N148_Q1.8250.88
478_K482_E1.8040.87
593_S597_R1.7920.87
207_N210_W1.7840.86
148_Q151_V1.7700.86
455_S458_L1.7580.86
413_L422_G1.7450.85
158_Y179_D1.7380.85
416_Y424_A1.7340.85
288_Q291_Y1.7310.85
417_K422_G1.7130.84
152_F157_V1.6980.83
412_A417_K1.6960.83
339_V384_Q1.6810.83
318_V331_D1.6680.82
415_S419_Y1.6600.82
419_Y425_S1.6570.82
118_P159_P1.6550.82
323_A378_G1.6490.82
119_N155_P1.6490.82
327_E359_N1.6390.81
590_K593_S1.6290.81
186_S190_G1.6000.80
148_Q157_V1.6000.80
387_Q390_Q1.5950.79
146_V151_V1.5840.79
366_L391_V1.5830.79
452_E456_L1.5820.79
119_N150_G1.5760.79
291_Y295_P1.5630.78
219_E369_G1.5580.78
291_Y308_R1.5570.78
303_I306_D1.5530.77
150_G155_P1.5450.77
412_A422_G1.5430.77
322_V340_D1.5390.77
148_Q179_D1.5350.77
66_I71_L1.5300.76
156_S179_D1.5300.76
478_K481_Q1.5270.76
146_V152_F1.5170.76
412_A416_Y1.5160.76
596_E599_E1.5140.76
243_S267_F1.5120.76
153_E158_Y1.5090.75
512_F516_N1.4990.75
146_V177_E1.4910.74
413_L416_Y1.4900.74
246_S250_E1.4850.74
154_D158_Y1.4830.74
461_L470_G1.4820.74
513_S516_N1.4760.74
148_Q155_P1.4760.74
118_P148_Q1.4740.74
157_V179_D1.4730.74
591_T595_L1.4710.73
151_V179_D1.4690.73
590_K597_R1.4630.73
295_P309_R1.4520.72
118_P158_Y1.4500.72
280_W335_E1.4480.72
147_S150_G1.4440.72
116_I159_P1.4430.72
312_Y336_Y1.4380.72
207_N213_L1.4330.71
416_Y422_G1.4260.71
592_I598_L1.4170.71
316_K331_D1.4140.70
88_S133_Y1.4130.70
268_I331_D1.4040.70
280_W331_D1.4000.70
412_A452_E1.3970.69
593_S596_E1.3950.69
118_P156_S1.3910.69
328_A359_N1.3910.69
412_A424_A1.3860.69
590_K595_L1.3840.69
502_L516_N1.3760.68
597_R604_P1.3750.68
591_T597_R1.3740.68
150_G159_P1.3720.68
308_R311_Q1.3680.68
243_S312_Y1.3660.68
143_I147_S1.3640.68
241_A307_L1.3640.68
138_H166_T1.3610.67
286_R291_Y1.3560.67
305_T309_R1.3550.67
241_A339_V1.3540.67
592_I597_R1.3530.67
419_Y423_S1.3510.67
207_N212_P1.3450.66
120_K124_A1.3410.66
119_N147_S1.3280.65
146_V157_V1.3240.65
291_Y294_K1.3150.65
153_E156_S1.3140.65
244_T307_L1.3110.64
145_D159_P1.3030.64
593_S599_E1.3010.64
147_S158_Y1.2970.64
486_P554_M1.2960.63
254_A290_D1.2960.63
144_C160_V1.2950.63
552_D557_T1.2850.63
595_L598_L1.2720.62
413_L425_S1.2710.62
590_K598_L1.2700.62
415_S424_A1.2700.62
152_F178_I1.2590.61
299_I303_I1.2590.61
155_P179_D1.2520.61
572_P583_D1.2490.61
250_E293_T1.2470.60
267_F339_V1.2430.60
306_D312_Y1.2430.60
252_T269_K1.2410.60
155_P159_P1.2390.60
151_V159_P1.2370.60
243_S307_L1.2370.60
151_V154_D1.2300.59
589_T597_R1.2300.59
244_T305_T1.2290.59
206_G213_L1.2270.59
116_I150_G1.2260.59
297_L307_L1.2250.59
144_C148_Q1.2240.59
590_K599_E1.2230.59
243_S336_Y1.2170.58
119_N179_D1.2170.58
475_L478_K1.2150.58
295_P307_L1.2130.58
352_R410_S1.2110.58
299_I304_I1.2100.58
152_F156_S1.2100.58
309_R312_Y1.2080.58
594_P599_E1.1990.57
145_D148_Q1.1990.57
119_N159_P1.1880.57
590_K596_E1.1870.57
148_Q152_F1.1830.56
593_S598_L1.1790.56
593_S604_P1.1730.56
287_H308_R1.1730.56
298_D307_L1.1670.55
267_F342_N1.1660.55
152_F162_P1.1650.55
357_I393_V1.1620.55
589_T594_P1.1620.55
417_K423_S1.1580.55
120_K155_P1.1560.54
295_P312_Y1.1530.54
155_P158_Y1.1520.54
146_V150_G1.1510.54
147_S156_S1.1470.54
590_K600_N1.1470.54
321_K384_Q1.1430.54
382_Q387_Q1.1420.54
441_E445_R1.1420.54
57_D108_R1.1390.53
591_T599_E1.1370.53
482_E485_M1.1320.53
152_F158_Y1.1320.53
148_Q153_E1.1310.53
118_P145_D1.1310.53
294_K306_D1.1290.53
593_S600_N1.1280.53
116_I156_S1.1170.52
239_V389_K1.1150.52
244_T339_V1.1110.52
507_I512_F1.1070.51
589_T595_L1.1070.51
523_V529_P1.1040.51
597_R601_L1.1010.51
118_P150_G1.0990.51
287_H306_D1.0990.51
338_S343_L1.0980.51
590_K605_D1.0980.51
143_I150_G1.0970.51
245_A248_A1.0970.51
605_D624_N1.0950.50
321_K342_N1.0910.50
592_I596_E1.0890.50
186_S191_S1.0880.50
591_T594_P1.0860.50
487_A547_E1.0850.50
600_N604_P1.0830.50
589_T596_E1.0820.50
87_N91_D1.0810.50
150_G177_E1.0760.49
461_L472_P1.0750.49
321_K378_G1.0700.49
296_V307_L1.0690.49
177_E180_K1.0690.49
203_T210_W1.0660.49
590_K604_P1.0660.49
502_L506_R1.0650.48
144_C159_P1.0640.48
147_S159_P1.0630.48
241_A312_Y1.0570.48
205_I209_L1.0550.48
502_L512_F1.0530.48
547_E567_I1.0490.47
119_N157_V1.0480.47
97_V119_N1.0470.47
119_N145_D1.0470.47
154_D157_V1.0460.47
507_I510_V1.0450.47
602_V605_D1.0450.47
145_D155_P1.0430.47
116_I147_S1.0420.47
573_E583_D1.0400.47
287_H307_L1.0390.47
338_S342_N1.0370.47
157_V178_I1.0340.46
241_A385_A1.0330.46
267_F384_Q1.0270.46
246_S305_T1.0270.46
104_L113_V1.0200.45
475_L481_Q1.0190.45
114_G163_F1.0140.45
205_I212_P1.0140.45
604_P612_G1.0120.45
413_L423_S1.0120.45
378_G382_Q1.0050.44
288_Q295_P1.0030.44
146_V179_D0.9980.44
342_N384_Q0.9980.44
604_P608_A0.9960.44
294_K297_L0.9960.44
589_T593_S0.9900.44
322_V382_Q0.9880.43
592_I599_E0.9880.43
248_A267_F0.9840.43
438_F482_E0.9840.43
300_D303_I0.9820.43
68_A71_L0.9810.43
601_L604_P0.9780.43
357_I363_V0.9770.43
151_V155_P0.9760.43
490_V494_L0.9750.43
599_E602_V0.9750.43
609_I613_L0.9740.42
291_Y307_L0.9740.42
449_L452_E0.9720.42
150_G153_E0.9710.42
241_A384_Q0.9700.42
597_R602_V0.9690.42
461_L466_I0.9670.42
206_G209_L0.9650.42
615_K621_Q0.9610.42
602_V608_A0.9600.42
116_I119_N0.9590.42
145_D150_G0.9580.41
506_R516_N0.9570.41
406_G419_Y0.9540.41
234_D389_K0.9520.41
462_D467_P0.9520.41
601_L605_D0.9520.41
604_P613_L0.9510.41
578_A587_S0.9510.41
190_G194_M0.9470.41
243_S338_S0.9440.41
267_F341_T0.9430.40
265_K313_N0.9430.40
205_I213_L0.9420.40
422_G425_S0.9400.40
156_S159_P0.9340.40
96_Y119_N0.9340.40
476_E482_E0.9330.40
322_V381_F0.9320.40
144_C179_D0.9310.40
480_L484_H0.9310.40
597_R612_G0.9250.39
115_L118_P0.9250.39
328_A358_L0.9240.39
252_T340_D0.9210.39
242_S312_Y0.9150.39
116_I145_D0.9130.39
605_D614_E0.9130.39
146_V156_S0.9100.38
206_G210_W0.9080.38
506_R512_F0.9080.38
599_E615_K0.9070.38
191_S194_M0.9060.38
435_A481_Q0.8990.38
223_F366_L0.8990.38
147_S160_V0.8980.38
315_E330_V0.8970.38
412_A415_S0.8930.37
331_D343_L0.8920.37
477_G485_M0.8920.37
596_E600_N0.8910.37
483_L567_I0.8900.37
118_P179_D0.8900.37
296_V303_I0.8900.37
150_G160_V0.8890.37
297_L303_I0.8890.37
299_I307_L0.8870.37
597_R600_N0.8850.37
267_F321_K0.8850.37
591_T606_L0.8840.37
145_D160_V0.8830.37
593_S603_L0.8820.37
608_A622_D0.8800.37
156_S177_E0.8800.37
624_N627_D0.8800.37
148_Q160_V0.8790.36
265_K288_Q0.8770.36
97_V155_P0.8770.36
415_S425_S0.8750.36
591_T598_L0.8740.36
306_D336_Y0.8710.36
315_E332_T0.8700.36
115_L159_P0.8700.36
602_V609_I0.8690.36
119_N153_E0.8690.36
151_V177_E0.8690.36
605_D609_I0.8690.36
147_S179_D0.8680.36
590_K606_L0.8650.36
256_S260_P0.8640.36
619_V625_E0.8620.35
594_P598_L0.8590.35
608_A612_G0.8580.35
595_L605_D0.8570.35
526_S540_Y0.8560.35
97_V118_P0.8540.35
300_D307_L0.8530.35
242_S291_Y0.8510.35
96_Y118_P0.8510.35
326_L359_N0.8500.35
609_I617_E0.8480.35
246_S298_D0.8460.34
603_L612_G0.8440.34
119_N151_V0.8430.34
296_V306_D0.8430.34
595_L600_N0.8410.34
458_L467_P0.8390.34
287_H295_P0.8390.34
368_S383_F0.8380.34
240_Q307_L0.8370.34
243_S306_D0.8370.34
241_A246_S0.8330.34
507_I517_S0.8320.34
589_T598_L0.8260.33
478_K485_M0.8240.33
318_V341_T0.8210.33
118_P147_S0.8210.33
97_V148_Q0.8170.33
589_T592_I0.8170.33
124_A150_G0.8160.33
606_L609_I0.8160.33
294_K307_L0.8150.33
560_S568_E0.8130.32
326_L383_F0.8100.32
339_V343_L0.8100.32
140_M180_K0.8100.32
596_E604_P0.8100.32
446_I449_L0.8080.32
615_K619_V0.8080.32
206_G212_P0.8080.32
153_E179_D0.8070.32
481_Q485_M0.8060.32
291_Y313_N0.8050.32
257_E313_N0.8050.32
296_V305_T0.8050.32
599_E605_D0.8050.32
591_T604_P0.8020.32
367_Y388_L0.7980.32
600_N619_V0.7960.32
307_L336_Y0.7910.31
317_L328_A0.7860.31
599_E603_L0.7850.31
157_V177_E0.7840.31
603_L607_D0.7820.31
338_S385_A0.7810.31
603_L613_L0.7810.31
201_K205_I0.7780.30
551_Y555_V0.7780.30
608_A624_N0.7770.30
598_L603_L0.7770.30
439_L475_L0.7750.30
457_N474_D0.7750.30
612_G615_K0.7740.30
559_L562_K0.7740.30
147_S152_F0.7720.30
413_L418_A0.7690.30
299_I306_D0.7680.30
120_K158_Y0.7680.30
435_A477_G0.7680.30
589_T601_L0.7670.30
146_V158_Y0.7660.30
593_S602_V0.7650.30
454_E461_L0.7650.30
595_L601_L0.7640.30
93_Y126_Y0.7580.29
479_S570_F0.7580.29
378_G383_F0.7570.29
590_K612_G0.7560.29
251_F297_L0.7560.29
143_I155_P0.7560.29
605_D612_G0.7530.29
597_R605_D0.7510.29
118_P143_I0.7500.29
595_L604_P0.7460.29
603_L606_L0.7450.29
595_L612_G0.7430.29
607_D616_Y0.7420.29
264_N286_R0.7420.29
340_D384_Q0.7410.28
418_A424_A0.7410.28
196_V201_K0.7410.28
509_G512_F0.7410.28
331_D342_N0.7390.28
612_G620_R0.7390.28
242_S295_P0.7380.28
540_Y567_I0.7380.28
342_N359_N0.7380.28
611_N615_K0.7380.28
280_W316_K0.7380.28
602_V606_L0.7370.28
292_Y296_V0.7370.28
297_L305_T0.7370.28
604_P609_I0.7350.28
435_A482_E0.7340.28
266_K334_G0.7330.28
124_A155_P0.7330.28
290_D309_R0.7310.28
308_R312_Y0.7310.28
143_I148_Q0.7310.28
143_I159_P0.7300.28
619_V626_L0.7300.28
118_P153_E0.7290.28
203_T213_L0.7280.28
595_L602_V0.7270.28
115_L119_N0.7260.28
201_K206_G0.7240.28
148_Q159_P0.7240.28
100_L103_S0.7230.27
286_R308_R0.7220.27
616_Y626_L0.7200.27
155_P160_V0.7200.27
500_E521_M0.7200.27
152_F177_E0.7200.27
145_D179_D0.7190.27
613_L621_Q0.7190.27
244_T312_Y0.7190.27
289_G295_P0.7180.27
608_A611_N0.7150.27
241_A338_S0.7120.27
297_L308_R0.7120.27
269_K283_E0.7120.27
603_L608_A0.7100.27
594_P604_P0.7050.27
113_V119_N0.7030.26
597_R606_L0.7030.26
439_L478_K0.7020.26
308_R386_P0.7000.26
438_F477_G0.6990.26
416_Y425_S0.6980.26
593_S601_L0.6980.26
600_N622_D0.6970.26
423_S481_Q0.6960.26
287_H291_Y0.6940.26
103_S113_V0.6930.26
608_A613_L0.6930.26
449_L456_L0.6930.26
598_L604_P0.6930.26
548_F561_D0.6900.26
342_N382_Q0.6870.26
324_S381_F0.6860.26
609_I615_K0.6860.26
288_Q308_R0.6850.26
295_P306_D0.6850.26
246_S306_D0.6850.26
591_T596_E0.6840.25
263_T288_Q0.6840.25
48_G51_K0.6840.25
239_V308_R0.6830.25
338_S378_G0.6830.25
591_T603_L0.6820.25
600_N605_D0.6820.25
299_I305_T0.6810.25
416_Y423_S0.6800.25
475_L485_M0.6800.25
555_V580_G0.6790.25
418_A422_G0.6780.25
598_L601_L0.6770.25
123_S218_E0.6760.25
339_V382_Q0.6750.25
144_C158_Y0.6740.25
614_E619_V0.6740.25
115_L147_S0.6710.25
186_S189_T0.6700.25
513_S517_S0.6700.25
602_V616_Y0.6700.25
115_L155_P0.6700.25
120_K156_S0.6700.25
475_L482_E0.6690.25
342_N387_Q0.6690.25
599_E604_P0.6680.25
415_S422_G0.6670.25
590_K601_L0.6660.25
591_T601_L0.6650.25
430_E433_D0.6640.24
528_K585_R0.6640.24
359_N387_Q0.6620.24
199_P205_I0.6610.24
323_A359_N0.6600.24
448_E452_E0.6600.24
187_I191_S0.6600.24
467_P471_I0.6590.24
156_S176_I0.6590.24
591_T613_L0.6580.24
321_K385_A0.6580.24
123_S145_D0.6580.24
268_I280_W0.6580.24
183_S186_S0.6570.24
240_Q244_T0.6550.24
134_I233_L0.6540.24
509_G535_R0.6540.24
295_P308_R0.6530.24
297_L306_D0.6530.24
298_D305_T0.6520.24
91_D98_L0.6510.24
143_I156_S0.6490.24
331_D335_E0.6480.24
455_S472_P0.6480.24
287_H309_R0.6460.24
604_P619_V0.6450.24
148_Q154_D0.6440.24
409_V413_L0.6440.24
116_I160_V0.6430.23
612_G616_Y0.6430.23
367_Y378_G0.6430.23
321_K387_Q0.6430.23
592_I616_Y0.6430.23
318_V335_E0.6420.23
493_T550_T0.6410.23
604_P610_K0.6400.23
202_L207_N0.6400.23
477_G484_H0.6370.23
414_D417_K0.6370.23
241_A305_T0.6360.23
605_D615_K0.6360.23
466_I469_A0.6360.23
500_E517_S0.6350.23
512_F522_S0.6340.23
287_H297_L0.6330.23
118_P124_A0.6320.23
113_V116_I0.6320.23
120_K160_V0.6310.23
592_I612_G0.6310.23
118_P157_V0.6300.23
592_I600_N0.6300.23
613_L619_V0.6290.23
252_T281_N0.6280.23
363_V391_V0.6280.23
288_Q294_K0.6270.23
411_T448_E0.6260.23
144_C151_V0.6260.23
594_P605_D0.6260.23
367_Y383_F0.6250.23
280_W332_T0.6250.23
406_G413_L0.6230.23
156_S160_V0.6220.22
596_E602_V0.6220.22
599_E606_L0.6220.22
602_V615_K0.6220.22
124_A145_D0.6220.22
254_A295_P0.6210.22
591_T602_V0.6200.22
342_N385_A0.6180.22
603_L609_I0.6180.22
589_T616_Y0.6180.22
604_P622_D0.6170.22
145_D158_Y0.6170.22
205_I210_W0.6160.22
120_K147_S0.6150.22
592_I604_P0.6140.22
608_A615_K0.6140.22
258_E290_D0.6140.22
339_V342_N0.6100.22
240_Q308_R0.6100.22
476_E481_Q0.6090.22
116_I148_Q0.6080.22
124_A158_Y0.6070.22
512_F517_S0.6070.22
604_P615_K0.6060.22
551_Y554_M0.6060.22
246_S296_V0.6050.22
153_E159_P0.6050.22
603_L624_N0.6050.22
97_V143_I0.6040.22
608_A626_L0.6030.22
118_P151_V0.6030.22
146_V153_E0.6020.22
268_I342_N0.6010.22
120_K127_A0.5990.21
291_Y297_L0.5990.21
267_F285_V0.5980.21
597_R603_L0.5980.21
620_R626_L0.5980.21
600_N615_K0.5970.21
120_K183_S0.5960.21
144_C157_V0.5960.21
412_A423_S0.5960.21
512_F515_D0.5960.21
241_A342_N0.5950.21
597_R613_L0.5940.21
148_Q177_E0.5930.21
272_G279_F0.5920.21
267_F385_A0.5920.21
417_K425_S0.5890.21
446_I452_E0.5890.21
591_T612_G0.5890.21
199_P207_N0.5870.21
268_I335_E0.5870.21
264_N291_Y0.5860.21
566_L570_F0.5850.21
241_A306_D0.5850.21
297_L304_I0.5850.21
298_D303_I0.5850.21
596_E616_Y0.5840.21
119_N143_I0.5830.21
150_G186_S0.5820.21
146_V160_V0.5810.21
339_V385_A0.5810.21
597_R616_Y0.5810.21
605_D626_L0.5800.21
600_N606_L0.5750.20
135_I143_I0.5750.20
116_I155_P0.5730.20
266_K335_E0.5730.20
317_L355_G0.5730.20
323_A367_Y0.5720.20
609_I612_G0.5720.20
623_A626_L0.5700.20
551_Y566_L0.5690.20
197_C201_K0.5690.20
568_E577_R0.5690.20
547_E580_G0.5690.20
590_K594_P0.5680.20
289_G308_R0.5680.20
610_K620_R0.5660.20
103_S117_V0.5640.20
608_A619_V0.5640.20
608_A617_E0.5630.20
240_Q334_G0.5630.20
610_K619_V0.5620.20
100_L115_L0.5620.20
591_T605_D0.5610.20
606_L619_V0.5610.20
599_E608_A0.5610.20
294_K312_Y0.5600.20
243_S285_V0.5590.20
115_L150_G0.5590.20
609_I621_Q0.5580.20
151_V176_I0.5580.20
203_T207_N0.5570.20
593_S605_D0.5560.20
548_F567_I0.5550.20
570_F577_R0.5550.20
67_N94_D0.5540.19
87_N92_A0.5540.19
466_I470_G0.5530.19
303_I309_R0.5530.19
300_D305_T0.5520.19
513_S559_L0.5520.19
313_N336_Y0.5520.19
439_L482_E0.5510.19
615_K624_N0.5500.19
148_Q162_P0.5500.19
160_V179_D0.5490.19
601_L624_N0.5490.19
287_H304_I0.5490.19
593_S612_G0.5490.19
568_E574_A0.5480.19
548_F551_Y0.5480.19
252_T267_F0.5470.19
607_D615_K0.5470.19
241_A252_T0.5460.19
101_E133_Y0.5460.19
442_L478_K0.5460.19
226_T366_L0.5450.19
61_G535_R0.5430.19
150_G154_D0.5420.19
605_D608_A0.5420.19
239_V244_T0.5410.19
438_F478_K0.5410.19
244_T308_R0.5410.19
452_E463_Y0.5400.19
606_L613_L0.5390.19
602_V613_L0.5390.19
353_Y357_I0.5390.19
153_E177_E0.5390.19
614_E621_Q0.5380.19
606_L618_D0.5380.19
603_L610_K0.5370.19
269_K320_A0.5360.19
507_I515_D0.5360.19
358_L363_V0.5360.19
540_Y580_G0.5350.19
140_M175_N0.5350.19
151_V162_P0.5350.19
438_F442_L0.5350.19
327_E378_G0.5340.19
602_V624_N0.5340.19
567_I575_V0.5340.19
590_K603_L0.5330.19
609_I614_E0.5320.19
605_D613_L0.5320.19
603_L611_N0.5320.19
115_L120_K0.5320.19
321_K327_E0.5310.19
269_K384_Q0.5310.19
343_L385_A0.5300.19
600_N613_L0.5300.19
609_I627_D0.5290.18
255_L260_P0.5290.18
145_D156_S0.5290.18
107_S113_V0.5280.18
220_Q469_A0.5280.18
257_E261_S0.5280.18
193_Q197_C0.5280.18
409_V424_A0.5270.18
592_I602_V0.5260.18
151_V160_V0.5260.18
601_L613_L0.5250.18
304_I309_R0.5230.18
323_A383_F0.5220.18
87_N101_E0.5220.18
603_L619_V0.5220.18
526_S582_A0.5220.18
151_V185_V0.5220.18
608_A625_E0.5210.18
606_L615_K0.5210.18
257_E290_D0.5210.18
596_E603_L0.5200.18
445_R456_L0.5190.18
118_P160_V0.5180.18
152_F160_V0.5180.18
609_I619_V0.5180.18
190_G195_D0.5180.18
119_N183_S0.5160.18
596_E606_L0.5150.18
115_L158_Y0.5140.18
183_S187_I0.5130.18
147_S154_D0.5120.18
600_N603_L0.5090.18
268_I341_T0.5090.18
417_K421_E0.5070.18
144_C161_I0.5070.18
609_I624_N0.5070.18
593_S608_A0.5060.18
341_T384_Q0.5060.18
465_G474_D0.5060.18
298_D304_I0.5050.18
412_A449_L0.5050.18
323_A382_Q0.5050.18
239_V321_K0.5050.18
530_D573_E0.5050.18
439_L481_Q0.5040.17
359_N378_G0.5040.17
595_L619_V0.5040.17
602_V614_E0.5030.17
615_K625_E0.5030.17
203_T212_P0.5030.17
362_V366_L0.5020.17
511_S535_R0.5020.17
592_I605_D0.5000.17
175_N192_E0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3s1sA 1 0.6853 100 0.829 Contact Map
2ih2A 1 0.5174 100 0.861 Contact Map
3khkA 1 0.351 99.7 0.915 Contact Map
3lkdA 1 0.3147 99.6 0.92 Contact Map
2okcA 1 0.3464 99.6 0.921 Contact Map
3ufbA 1 0.3419 99.6 0.923 Contact Map
2f8lA 1 0.2799 99.6 0.924 Contact Map
2ar0A 1 0.3888 99.6 0.924 Contact Map
1o9gA 1 0.1997 97.5 0.963 Contact Map
3evzA 1 0.1936 97.4 0.964 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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