O52000 - HALSA - GREMLIN Contacts

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O52000 - Uncharacterized protein

UniProt:	O52000	Sequences: MQTALTYRTNRDLFSNHYLDEHLPETEEWDEVSDEELQEAYDDIMALWEREKDTAPKRNESQLEEKFIRPMFRKLGIPFEVEESTSRTQRRPDYGFFDTEDAARDAFERREEGGDFYENAVAVADAKRWGRPLDTRGSGEHERDFENPSYQIHVYLQETPARWAVLTDGKKWRLYYGPTSHRLDSYYEVDLPTILESGDLEDFKYFYLFFRHEAFLDDGSGDCFLDDVYDESNVFAQELGEDLQDNIYEAIKILSEGYLQYPENDLDEGDLDLIHDSSLIYLYRLIFVLYAEAEGRELLDTSNEIYEQSYSLNSLKQEIAEELDSGDPKYRDWQDNLQSRLDELFTLINKGSKSRGIPEEDLYIPAYNGGLFRTDPDEDDSAEAKFLANHDVGDAYLAKVVELLTRSKNNDGGGKIFVDYSSLDVRHLGSIYEGLLEYQLNVADEPLALDDGEYVSADEGDDVVVQEGEVYLTTDSGERKATGSYYTPEYVVEYIVENTLEPLVDDIRADLAGRSARGEDRGFAEEFAERIFDLKILDPAMGSGHFLTSAIDYLAREIIDAQERQAAQQGIETVNQDHDINWARRQVAQRCIYGVDLNPLAVELAKVSLWLRTLAAEQPLAFLDHHLKTGNSLVGSNVEEIDALERNGAAEAEGPNSTLIDFGMTFEGTMENLMAIHADLIAIENEELEDVKAMEKKYQYITKPLS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	706 (612)
Sequences:	788 (556)
Seq/√Len:	22.5

HALSA - O52000 Q9HI06

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
597_L	631_N	7.613	1.00
336_N	394_D	6.382	1.00
44_I	48_W	5.588	1.00
676_I	680_L	4.679	1.00
152_I	164_A	4.312	1.00
541_M	627_L	4.268	1.00
77_I	215_F	4.021	1.00
552_D	612_R	3.591	1.00
665_T	669_T	3.449	1.00
654_G	666_F	3.385	1.00
605_A	627_L	3.376	1.00
686_E	690_D	3.215	1.00
429_G	433_E	2.859	0.99
670_M	680_L	2.698	0.99
659_L	663_G	2.573	0.99
677_H	684_E	2.494	0.98
134_D	148_P	2.492	0.98
651_E	654_G	2.474	0.98
687_E	690_D	2.464	0.98
655_P	666_F	2.432	0.98
684_E	687_E	2.367	0.97
674_M	678_A	2.294	0.97
478_E	632_S	2.280	0.97
443_A	471_Y	2.279	0.97
659_L	662_F	2.277	0.97
288_V	341_L	2.270	0.97
480_K	485_Y	2.251	0.96
291_A	299_L	2.242	0.96
654_G	659_L	2.208	0.96
657_S	660_I	2.203	0.96
529_E	562_Q	2.195	0.96
68_I	167_T	2.187	0.96
428_L	539_P	2.165	0.96
656_N	662_F	2.135	0.95
599_P	629_T	2.087	0.95
59_N	62_Q	2.083	0.95
11_R	14_F	2.082	0.94
652_A	657_S	2.077	0.94
128_R	131_R	2.071	0.94
496_V	554_L	2.068	0.94
656_N	659_L	2.012	0.93
279_L	484_S	2.007	0.93
523_F	526_E	1.975	0.93
652_A	655_P	1.975	0.93
45_M	49_E	1.966	0.93
557_E	560_D	1.963	0.93
261_Y	264_N	1.934	0.92
606_K	624_D	1.930	0.92
167_T	172_W	1.920	0.92
232_S	434_G	1.915	0.92
172_W	206_F	1.890	0.91
653_E	656_N	1.890	0.91
344_L	584_R	1.876	0.91
489_E	545_H	1.875	0.91
419_D	545_H	1.860	0.90
683_I	686_E	1.856	0.90
677_H	680_L	1.835	0.90
57_K	60_E	1.819	0.89
496_V	553_Y	1.815	0.89
681_I	684_E	1.811	0.89
75_L	423_L	1.811	0.89
91_R	95_G	1.809	0.89
345_F	372_F	1.806	0.89
494_Y	498_N	1.801	0.89
555_A	583_A	1.792	0.89
653_E	665_T	1.792	0.89
653_E	666_F	1.784	0.88
662_F	676_I	1.781	0.88
528_A	561_A	1.772	0.88
36_E	47_L	1.766	0.88
36_E	48_W	1.763	0.88
661_D	666_F	1.762	0.88
677_H	681_I	1.757	0.88
587_V	622_F	1.755	0.87
669_T	672_N	1.741	0.87
253_I	396_Y	1.737	0.87
334_Q	394_D	1.721	0.86
658_T	670_M	1.704	0.86
674_M	677_H	1.695	0.86
687_E	691_V	1.671	0.85
667_E	670_M	1.668	0.85
44_I	47_L	1.661	0.84
655_P	659_L	1.659	0.84
341_L	393_G	1.655	0.84
545_H	612_R	1.654	0.84
670_M	677_H	1.648	0.84
488_P	611_L	1.645	0.84
420_Y	432_Y	1.640	0.84
165_V	268_E	1.636	0.83
666_F	670_M	1.625	0.83
654_G	662_F	1.609	0.82
247_I	291_A	1.605	0.82
655_P	663_G	1.604	0.82
287_F	620_L	1.604	0.82
189_V	210_F	1.602	0.82
432_Y	604_L	1.598	0.82
40_A	50_R	1.592	0.82
685_N	688_L	1.587	0.81
543_S	633_L	1.585	0.81
654_G	657_S	1.584	0.81
292_E	630_G	1.582	0.81
149_S	166_L	1.580	0.81
302_S	307_E	1.574	0.81
443_A	468_G	1.566	0.81
127_K	155_Y	1.562	0.80
156_L	164_A	1.557	0.80
153_H	157_Q	1.554	0.80
673_L	677_H	1.534	0.79
169_G	435_L	1.533	0.79
658_T	661_D	1.531	0.79
670_M	681_I	1.528	0.79
404_L	423_L	1.516	0.78
369_G	621_A	1.514	0.78
678_A	681_I	1.511	0.78
588_A	613_T	1.510	0.78
663_G	666_F	1.509	0.78
298_L	606_K	1.505	0.78
68_I	72_F	1.505	0.78
556_R	580_I	1.496	0.77
666_F	680_L	1.493	0.77
243_L	432_Y	1.492	0.77
653_E	661_D	1.492	0.77
483_G	538_D	1.485	0.77
127_K	131_R	1.482	0.77
558_I	591_C	1.475	0.76
148_P	166_L	1.471	0.76
655_P	662_F	1.471	0.76
665_T	677_H	1.466	0.76
199_D	202_D	1.461	0.76
420_Y	604_L	1.454	0.75
683_I	687_E	1.452	0.75
19_L	22_H	1.445	0.75
251_I	278_S	1.439	0.75
164_A	212_H	1.432	0.74
383_E	499_T	1.426	0.74
600_L	621_A	1.421	0.74
584_R	612_R	1.421	0.74
470_V	597_L	1.418	0.73
503_L	534_L	1.413	0.73
642_D	680_L	1.405	0.73
657_S	670_M	1.391	0.72
671_E	675_A	1.387	0.72
251_I	255_S	1.380	0.71
675_A	678_A	1.376	0.71
625_H	628_K	1.374	0.71
686_E	691_V	1.373	0.71
662_F	666_F	1.367	0.71
171_K	188_E	1.365	0.70
657_S	680_L	1.365	0.70
38_Q	43_D	1.363	0.70
538_D	620_L	1.349	0.70
279_L	435_L	1.345	0.69
658_T	662_F	1.341	0.69
129_W	133_L	1.339	0.69
492_V	549_S	1.338	0.69
55_A	58_R	1.338	0.69
367_Y	470_V	1.334	0.69
341_L	345_F	1.331	0.68
165_V	308_Q	1.326	0.68
132_P	135_T	1.322	0.68
655_P	670_M	1.320	0.68
420_Y	622_F	1.318	0.68
33_S	44_I	1.314	0.67
257_G	430_S	1.309	0.67
141_H	536_I	1.303	0.67
429_G	479_R	1.302	0.67
338_Q	624_D	1.290	0.66
656_N	680_L	1.283	0.66
677_H	687_E	1.282	0.66
658_T	664_M	1.280	0.65
601_A	605_A	1.280	0.65
349_N	428_L	1.280	0.65
661_D	678_A	1.278	0.65
94_Y	98_D	1.277	0.65
339_S	342_D	1.275	0.65
505_D	526_E	1.270	0.65
93_D	96_F	1.270	0.65
88_T	91_R	1.269	0.65
478_E	482_T	1.267	0.65
404_L	430_S	1.265	0.64
410_N	413_G	1.262	0.64
345_F	492_V	1.262	0.64
655_P	677_H	1.261	0.64
621_A	631_N	1.260	0.64
589_Q	618_Q	1.257	0.64
532_F	555_A	1.248	0.63
675_A	683_I	1.247	0.63
322_E	613_T	1.244	0.63
342_D	428_L	1.244	0.63
274_I	611_L	1.243	0.63
652_A	666_F	1.241	0.63
656_N	661_D	1.239	0.63
169_G	635_G	1.238	0.63
663_G	667_E	1.237	0.63
653_E	664_M	1.236	0.63
420_Y	423_L	1.234	0.62
659_L	673_L	1.229	0.62
162_R	177_G	1.225	0.62
119_N	536_I	1.224	0.62
657_S	661_D	1.224	0.62
22_H	225_L	1.223	0.62
661_D	667_E	1.222	0.62
369_G	480_K	1.213	0.61
660_I	675_A	1.212	0.61
662_F	683_I	1.210	0.61
40_A	43_D	1.206	0.61
671_E	678_A	1.203	0.60
341_L	397_L	1.203	0.60
655_P	658_T	1.203	0.60
393_G	396_Y	1.199	0.60
364_I	614_L	1.198	0.60
291_A	600_L	1.198	0.60
664_M	669_T	1.198	0.60
349_N	370_G	1.197	0.60
654_G	680_L	1.197	0.60
650_A	654_G	1.195	0.60
371_L	546_F	1.189	0.60
651_E	655_P	1.187	0.59
346_T	350_K	1.185	0.59
426_R	591_C	1.183	0.59
652_A	677_H	1.178	0.59
426_R	548_T	1.178	0.59
341_L	634_V	1.177	0.59
279_L	604_L	1.176	0.59
239_L	310_Y	1.172	0.58
657_S	664_M	1.171	0.58
429_G	436_L	1.169	0.58
661_D	684_E	1.167	0.58
41_Y	46_A	1.165	0.58
304_E	308_Q	1.160	0.58
40_A	48_W	1.158	0.57
539_P	546_F	1.156	0.57
426_R	433_E	1.154	0.57
546_F	633_L	1.153	0.57
609_L	630_G	1.153	0.57
243_L	532_F	1.151	0.57
243_L	436_L	1.149	0.57
668_G	682_A	1.149	0.57
133_L	499_T	1.149	0.57
288_V	348_I	1.148	0.57
683_I	690_D	1.148	0.57
490_Y	494_Y	1.147	0.57
528_A	558_I	1.147	0.57
665_T	670_M	1.147	0.57
289_L	632_S	1.146	0.57
243_L	433_E	1.145	0.57
541_M	594_G	1.143	0.56
642_D	645_E	1.143	0.56
685_N	690_D	1.142	0.56
682_A	689_E	1.141	0.56
674_M	684_E	1.140	0.56
667_E	676_I	1.140	0.56
286_I	617_E	1.139	0.56
90_R	95_G	1.138	0.56
660_I	664_M	1.138	0.56
662_F	677_H	1.135	0.56
528_A	562_Q	1.135	0.56
335_D	391_D	1.132	0.56
121_V	605_A	1.129	0.56
658_T	676_I	1.126	0.55
541_M	584_R	1.125	0.55
650_A	655_P	1.125	0.55
611_L	627_L	1.118	0.55
598_N	610_W	1.118	0.55
151_Q	368_N	1.117	0.55
651_E	658_T	1.116	0.55
153_H	156_L	1.113	0.54
663_G	670_M	1.113	0.54
243_L	635_G	1.110	0.54
657_S	668_G	1.104	0.54
384_A	387_L	1.101	0.54
676_I	681_I	1.096	0.53
683_I	692_K	1.095	0.53
437_E	545_H	1.095	0.53
432_Y	436_L	1.091	0.53
188_E	545_H	1.089	0.53
606_K	622_F	1.088	0.53
332_D	587_V	1.083	0.52
523_F	527_F	1.078	0.52
476_S	537_L	1.077	0.52
539_P	632_S	1.077	0.52
420_Y	539_P	1.077	0.52
650_A	687_E	1.069	0.51
600_L	624_D	1.061	0.51
147_N	150_Y	1.060	0.51
658_T	666_F	1.059	0.51
465_V	469_E	1.058	0.51
683_I	689_E	1.056	0.51
465_V	471_Y	1.056	0.51
555_A	558_I	1.055	0.50
183_L	608_S	1.051	0.50
622_F	625_H	1.050	0.50
661_D	665_T	1.049	0.50
173_R	369_G	1.049	0.50
536_I	647_N	1.048	0.50
662_F	675_A	1.047	0.50
639_E	689_E	1.047	0.50
240_G	367_Y	1.046	0.50
433_E	486_Y	1.046	0.50
675_A	684_E	1.044	0.50
344_L	632_S	1.043	0.50
341_L	344_L	1.042	0.50
243_L	429_G	1.039	0.49
306_Y	555_A	1.038	0.49
247_I	600_L	1.036	0.49
39_E	43_D	1.032	0.49
93_D	97_F	1.032	0.49
658_T	692_K	1.030	0.49
249_E	403_L	1.029	0.49
540_A	597_L	1.029	0.49
186_Y	259_L	1.029	0.49
499_T	502_P	1.026	0.48
295_G	302_S	1.025	0.48
660_I	690_D	1.022	0.48
208_L	608_S	1.021	0.48
279_L	283_Y	1.021	0.48
432_Y	622_F	1.019	0.48
475_D	592_I	1.018	0.48
41_Y	49_E	1.017	0.48
562_Q	566_A	1.017	0.48
563_E	566_A	1.015	0.48
653_E	667_E	1.013	0.48
222_D	647_N	1.012	0.47
345_F	595_V	1.010	0.47
659_L	670_M	1.008	0.47
665_T	672_N	1.008	0.47
656_N	667_E	1.006	0.47
35_E	38_Q	1.005	0.47
36_E	41_Y	1.003	0.47
53_D	56_P	1.003	0.47
651_E	677_H	1.003	0.47
305_I	634_V	1.001	0.47
645_E	649_A	1.000	0.47
12_D	535_K	0.997	0.46
230_D	234_V	0.995	0.46
279_L	285_L	0.995	0.46
543_S	547_L	0.994	0.46
665_T	676_I	0.994	0.46
555_A	584_R	0.993	0.46
285_L	365_P	0.993	0.46
211_R	214_A	0.992	0.46
401_V	405_T	0.991	0.46
36_E	50_R	0.991	0.46
434_G	482_T	0.985	0.46
404_L	604_L	0.981	0.45
15_S	24_P	0.977	0.45
675_A	679_D	0.976	0.45
676_I	679_D	0.975	0.45
541_M	551_I	0.972	0.45
672_N	683_I	0.972	0.45
271_L	590_R	0.972	0.45
286_I	337_L	0.971	0.45
665_T	684_E	0.970	0.45
240_G	251_I	0.969	0.45
319_I	593_Y	0.968	0.44
653_E	677_H	0.966	0.44
26_T	71_M	0.964	0.44
146_E	155_Y	0.964	0.44
656_N	683_I	0.963	0.44
610_W	630_G	0.961	0.44
339_S	394_D	0.961	0.44
20_D	24_P	0.959	0.44
246_N	250_A	0.959	0.44
33_S	46_A	0.958	0.44
187_Y	482_T	0.957	0.44
36_E	46_A	0.955	0.44
75_L	206_F	0.954	0.44
654_G	670_M	0.954	0.44
484_S	604_L	0.954	0.44
432_Y	532_F	0.952	0.43
165_V	307_E	0.948	0.43
672_N	682_A	0.947	0.43
660_I	676_I	0.945	0.43
163_W	174_L	0.940	0.43
591_C	624_D	0.938	0.42
661_D	676_I	0.935	0.42
675_A	687_E	0.935	0.42
384_A	388_A	0.935	0.42
15_S	34_D	0.934	0.42
665_T	678_A	0.933	0.42
189_V	211_R	0.929	0.42
654_G	658_T	0.927	0.42
54_T	58_R	0.927	0.42
251_I	435_L	0.926	0.42
428_L	546_F	0.925	0.42
64_E	70_P	0.925	0.42
654_G	681_I	0.925	0.42
679_D	691_V	0.925	0.42
71_M	206_F	0.922	0.41
425_V	438_Y	0.918	0.41
268_E	304_E	0.918	0.41
654_G	677_H	0.917	0.41
332_D	395_A	0.915	0.41
294_E	436_L	0.913	0.41
43_D	48_W	0.912	0.41
39_E	196_E	0.911	0.41
92_P	97_F	0.911	0.41
646_R	649_A	0.910	0.41
63_L	70_P	0.909	0.41
654_G	667_E	0.907	0.40
658_T	683_I	0.906	0.40
656_N	664_M	0.903	0.40
489_E	493_E	0.902	0.40
666_F	678_A	0.902	0.40
558_I	622_F	0.901	0.40
587_V	591_C	0.901	0.40
663_G	678_A	0.900	0.40
90_R	93_D	0.899	0.40
665_T	682_A	0.897	0.40
163_W	254_L	0.895	0.40
254_L	278_S	0.894	0.40
668_G	671_E	0.893	0.39
177_G	195_L	0.893	0.39
591_C	641_I	0.892	0.39
436_L	479_R	0.891	0.39
654_G	661_D	0.890	0.39
680_L	683_I	0.890	0.39
345_F	371_L	0.886	0.39
289_L	405_T	0.886	0.39
120_A	123_V	0.883	0.39
504_V	557_E	0.882	0.39
367_Y	431_I	0.882	0.39
195_L	206_F	0.882	0.39
41_Y	45_M	0.880	0.39
77_I	394_D	0.880	0.39
65_E	123_V	0.875	0.38
292_E	598_N	0.875	0.38
341_L	602_V	0.875	0.38
435_L	484_S	0.873	0.38
498_N	501_E	0.870	0.38
64_E	67_F	0.869	0.38
653_E	662_F	0.868	0.38
618_Q	641_I	0.867	0.38
432_Y	635_G	0.866	0.38
652_A	658_T	0.865	0.38
371_L	544_G	0.863	0.38
507_I	534_L	0.859	0.37
443_A	447_L	0.859	0.37
316_K	394_D	0.857	0.37
240_G	545_H	0.855	0.37
675_A	689_E	0.854	0.37
689_E	692_K	0.853	0.37
14_F	24_P	0.852	0.37
602_V	632_S	0.851	0.37
656_N	668_G	0.850	0.37
247_I	432_Y	0.850	0.37
491_V	532_F	0.848	0.37
168_D	171_K	0.847	0.36
344_L	621_A	0.846	0.36
88_T	96_F	0.844	0.36
123_V	126_A	0.842	0.36
667_E	680_L	0.841	0.36
446_P	536_I	0.838	0.36
345_F	632_S	0.838	0.36
547_L	633_L	0.836	0.36
538_D	623_L	0.835	0.36
154_V	157_Q	0.835	0.36
246_N	428_L	0.833	0.36
371_L	632_S	0.830	0.35
532_F	622_F	0.829	0.35
631_N	634_V	0.828	0.35
543_S	632_S	0.826	0.35
658_T	677_H	0.826	0.35
652_A	661_D	0.826	0.35
663_G	676_I	0.825	0.35
499_T	634_V	0.825	0.35
431_I	621_A	0.823	0.35
173_R	188_E	0.823	0.35
283_Y	484_S	0.819	0.35
590_R	626_H	0.819	0.35
676_I	684_E	0.819	0.35
46_A	50_R	0.818	0.35
528_A	588_A	0.817	0.35
240_G	419_D	0.815	0.34
53_D	395_A	0.815	0.34
656_N	677_H	0.812	0.34
41_Y	48_W	0.811	0.34
76_G	191_L	0.810	0.34
659_L	666_F	0.808	0.34
58_R	63_L	0.808	0.34
654_G	663_G	0.808	0.34
681_I	687_E	0.807	0.34
666_F	684_E	0.806	0.34
261_Y	323_L	0.805	0.34
406_R	580_I	0.803	0.34
654_G	678_A	0.803	0.34
653_E	657_S	0.802	0.34
426_R	552_D	0.801	0.34
671_E	682_A	0.800	0.34
493_E	634_V	0.800	0.34
62_Q	65_E	0.799	0.33
652_A	656_N	0.798	0.33
551_I	584_R	0.798	0.33
348_I	367_Y	0.796	0.33
420_Y	626_H	0.795	0.33
163_W	223_C	0.794	0.33
433_E	479_R	0.794	0.33
230_D	233_N	0.793	0.33
264_N	375_D	0.791	0.33
212_H	573_T	0.791	0.33
437_E	591_C	0.791	0.33
162_R	228_V	0.790	0.33
290_Y	545_H	0.787	0.33
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662_F	670_M	0.784	0.33
652_A	664_M	0.781	0.32
684_E	688_L	0.781	0.32
312_L	541_M	0.781	0.32
321_E	353_K	0.781	0.32
351_G	429_G	0.778	0.32
470_V	475_D	0.775	0.32
202_D	626_H	0.775	0.32
308_Q	399_K	0.775	0.32
133_L	611_L	0.775	0.32
419_D	430_S	0.772	0.32
653_E	658_T	0.772	0.32
310_Y	419_D	0.771	0.32
69_R	78_P	0.768	0.32
82_E	95_G	0.766	0.31
367_Y	553_Y	0.766	0.31
551_I	592_I	0.766	0.31
585_R	619_P	0.765	0.31
603_E	611_L	0.761	0.31
548_T	557_E	0.761	0.31
551_I	588_A	0.761	0.31
665_T	668_G	0.759	0.31
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426_R	492_V	0.757	0.31
369_G	619_P	0.757	0.31
75_L	404_L	0.757	0.31
283_Y	604_L	0.755	0.31
284_R	621_A	0.751	0.31
432_Y	482_T	0.750	0.31
432_Y	555_A	0.750	0.31
536_I	556_R	0.749	0.30
666_F	676_I	0.748	0.30
595_V	628_K	0.747	0.30
225_L	547_L	0.747	0.30
243_L	585_R	0.744	0.30
68_I	126_A	0.744	0.30
679_D	686_E	0.743	0.30
21_E	466_Q	0.742	0.30
549_S	553_Y	0.742	0.30
80_E	213_E	0.742	0.30
551_I	607_V	0.742	0.30
173_R	480_K	0.741	0.30
667_E	677_H	0.738	0.30
166_L	608_S	0.738	0.30
165_V	271_L	0.737	0.30
392_V	606_K	0.737	0.30
306_Y	315_L	0.736	0.30
306_Y	532_F	0.736	0.30
167_T	608_S	0.735	0.30
152_I	550_A	0.734	0.30
163_W	397_L	0.734	0.30
299_L	614_L	0.733	0.30
164_A	502_P	0.732	0.30
156_L	159_T	0.732	0.30
661_D	664_M	0.731	0.29
126_A	129_W	0.730	0.29
658_T	681_I	0.730	0.29
434_G	626_H	0.728	0.29
558_I	583_A	0.726	0.29
155_Y	368_N	0.726	0.29
480_K	538_D	0.726	0.29
231_E	467_E	0.724	0.29
283_Y	430_S	0.723	0.29
274_I	470_V	0.722	0.29
282_L	436_L	0.721	0.29
667_E	678_A	0.721	0.29
437_E	625_H	0.719	0.29
194_I	251_I	0.719	0.29
50_R	388_A	0.718	0.29
17_H	240_G	0.718	0.29
43_D	53_D	0.716	0.29
174_L	209_F	0.715	0.29
487_T	491_V	0.715	0.29
426_R	489_E	0.715	0.29
229_Y	548_T	0.710	0.28
429_G	432_Y	0.709	0.28
544_G	620_L	0.709	0.28
551_I	612_R	0.709	0.28
348_I	627_L	0.708	0.28
92_P	98_D	0.707	0.28
427_H	432_Y	0.707	0.28
657_S	674_M	0.707	0.28
660_I	684_E	0.707	0.28
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655_P	665_T	0.705	0.28
666_F	669_T	0.704	0.28
89_Q	92_P	0.702	0.28
40_A	44_I	0.700	0.28
370_G	620_L	0.700	0.28
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169_G	619_P	0.699	0.28
446_P	467_E	0.698	0.28
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17_H	416_I	0.696	0.27
169_G	404_L	0.694	0.27
351_G	433_E	0.694	0.27
222_D	230_D	0.694	0.27
368_N	620_L	0.693	0.27
54_T	73_R	0.691	0.27
416_I	588_A	0.691	0.27
677_H	688_L	0.689	0.27
298_L	585_R	0.688	0.27
231_E	534_L	0.687	0.27
589_Q	634_V	0.687	0.27
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11_R	16_N	0.686	0.27
436_L	481_A	0.686	0.27
318_E	332_D	0.684	0.27
423_L	429_G	0.684	0.27
683_I	691_V	0.683	0.27
430_S	475_D	0.682	0.27
284_R	554_L	0.682	0.27
345_F	407_S	0.680	0.27
477_G	482_T	0.680	0.27
72_F	435_L	0.674	0.26
188_E	203_F	0.673	0.26
228_V	240_G	0.672	0.26
431_I	589_Q	0.672	0.26
190_D	259_L	0.672	0.26
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267_D	642_D	0.671	0.26
657_S	671_E	0.671	0.26
394_D	397_L	0.671	0.26
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126_A	167_T	0.669	0.26
562_Q	586_Q	0.669	0.26
432_Y	491_V	0.669	0.26
288_V	590_R	0.668	0.26
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536_I	634_V	0.665	0.26
191_L	484_S	0.665	0.26
283_Y	432_Y	0.663	0.26
481_A	492_V	0.663	0.26
538_D	543_S	0.662	0.26
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678_A	684_E	0.661	0.26
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531_I	554_L	0.659	0.26
210_F	242_D	0.659	0.26
278_S	367_Y	0.657	0.25
288_V	312_L	0.657	0.25
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11_R	17_H	0.655	0.25
89_Q	94_Y	0.654	0.25
236_A	427_H	0.654	0.25
250_A	401_V	0.654	0.25
73_R	682_A	0.654	0.25
291_A	367_Y	0.653	0.25
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254_L	598_N	0.652	0.25
13_L	17_H	0.652	0.25
292_E	609_L	0.651	0.25
321_E	350_K	0.651	0.25
67_F	402_E	0.651	0.25
351_G	613_T	0.650	0.25
539_P	633_L	0.649	0.25
558_I	585_R	0.649	0.25
478_E	627_L	0.649	0.25
169_G	279_L	0.648	0.25
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58_R	85_T	0.646	0.25
582_W	615_A	0.645	0.25
651_E	659_L	0.645	0.25
664_M	668_G	0.644	0.25
420_Y	636_S	0.643	0.25
319_I	626_H	0.642	0.25
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418_V	551_I	0.642	0.25
47_L	50_R	0.639	0.24
643_A	648_G	0.638	0.24
439_Q	632_S	0.638	0.24
482_T	601_A	0.638	0.24
387_L	436_L	0.634	0.24
285_L	290_Y	0.633	0.24
666_F	677_H	0.633	0.24
52_K	57_K	0.632	0.24
313_N	316_K	0.631	0.24
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497_E	501_E	0.630	0.24
678_A	683_I	0.630	0.24
142_E	151_Q	0.629	0.24
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548_T	614_L	0.629	0.24
429_G	635_G	0.628	0.24
368_N	476_S	0.628	0.24
436_L	585_R	0.627	0.24
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480_K	483_G	0.627	0.24
658_T	674_M	0.627	0.24
538_D	624_D	0.626	0.24
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593_Y	627_L	0.626	0.24
660_I	670_M	0.626	0.24
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509_A	628_K	0.625	0.24
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539_P	595_V	0.624	0.24
584_R	627_L	0.623	0.24
651_E	661_D	0.622	0.24
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165_V	227_D	0.621	0.24
84_S	335_D	0.620	0.24
43_D	47_L	0.619	0.23
436_L	532_F	0.619	0.23
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197_S	202_D	0.616	0.23
660_I	671_E	0.616	0.23
492_V	545_H	0.616	0.23
622_F	635_G	0.615	0.23
365_P	619_P	0.614	0.23
504_V	536_I	0.612	0.23
651_E	678_A	0.611	0.23
129_W	170_K	0.611	0.23
591_C	625_H	0.611	0.23
642_D	683_I	0.610	0.23
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345_F	584_R	0.610	0.23
491_V	494_Y	0.610	0.23
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424_D	611_L	0.607	0.23
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601_A	627_L	0.605	0.23
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165_V	504_V	0.602	0.23
234_V	238_E	0.602	0.23
137_G	536_I	0.602	0.23
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419_D	422_S	0.601	0.23
288_V	310_Y	0.600	0.23
369_G	538_D	0.599	0.22
392_V	626_H	0.599	0.22
283_Y	622_F	0.598	0.22
438_Y	609_L	0.598	0.22
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606_K	623_L	0.597	0.22
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621_A	625_H	0.597	0.22
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529_E	682_A	0.596	0.22
283_Y	420_Y	0.595	0.22
587_V	624_D	0.592	0.22
498_N	539_P	0.592	0.22
152_I	616_A	0.592	0.22
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532_F	537_L	0.588	0.22
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279_L	588_A	0.586	0.22
254_L	398_A	0.585	0.22
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433_E	436_L	0.584	0.22
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484_S	598_N	0.583	0.22
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248_Y	252_K	0.581	0.22
299_L	585_R	0.581	0.22
129_W	291_A	0.578	0.22
686_E	689_E	0.578	0.22
666_F	681_I	0.576	0.21
676_I	688_L	0.574	0.21
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175_Y	626_H	0.571	0.21
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170_K	190_D	0.570	0.21
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442_V	446_P	0.569	0.21
528_A	586_Q	0.569	0.21
155_Y	620_L	0.568	0.21
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286_I	484_S	0.567	0.21
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652_A	678_A	0.566	0.21
529_E	536_I	0.565	0.21
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684_E	691_V	0.564	0.21
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187_Y	611_L	0.563	0.21
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427_H	611_L	0.559	0.21
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468_G	471_Y	0.556	0.21
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664_M	667_E	0.553	0.20
671_E	674_M	0.552	0.20
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642_D	692_K	0.551	0.20
270_D	346_T	0.550	0.20
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486_Y	532_F	0.542	0.20
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428_L	640_E	0.540	0.20
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629_T	634_V	0.539	0.20
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664_M	692_K	0.539	0.20
485_Y	546_F	0.538	0.20
190_D	335_D	0.538	0.20
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402_E	631_N	0.538	0.20
300_D	351_G	0.538	0.20
276_D	599_P	0.537	0.20
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435_L	584_R	0.535	0.20
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279_L	420_Y	0.531	0.19
538_D	585_R	0.530	0.19
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423_L	431_I	0.525	0.19
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279_L	528_A	0.524	0.19
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664_M	678_A	0.523	0.19
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674_M	681_I	0.521	0.19
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558_I	600_L	0.511	0.19
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490_Y	498_N	0.504	0.18
137_G	143_R	0.504	0.18
183_L	561_A	0.504	0.18
661_D	668_G	0.502	0.18
551_I	631_N	0.501	0.18
291_A	585_R	0.500	0.18
652_A	681_I	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2ar0A	1	0.3952	99.9	0.856	Contact Map
2okcA	1	0.4278	99.9	0.87	Contact Map
3khkA	1	0.4589	99.9	0.875	Contact Map
3lkdA	1	0.4603	99.9	0.878	Contact Map
3s1sA	1	0.619	99.8	0.881	Contact Map
3ufbA	1	0.4575	99.8	0.885	Contact Map
2f8lA	1	0.3499	99.7	0.9	Contact Map
2ih2A	1	0.204	99.4	0.918	Contact Map
3v97A	1	0.4816	98.6	0.94	Contact Map
1o9gA	1	0.2663	98.1	0.949	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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