GREMLIN Database
O51991 - SojD
UniProt: O51991 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 257 (234)
Sequences: 17563 (11545)
Seq/√Len: 754.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
19_T124_L3.7761.00
84_D120_Y3.7581.00
216_R244_V3.6681.00
31_H122_Y3.1771.00
29_R250_A3.1461.00
26_L122_Y3.0471.00
18_N245_Y2.8651.00
230_S233_G2.7961.00
5_A142_A2.7491.00
150_E186_N2.7081.00
192_D195_Q2.7071.00
35_A44_L2.5621.00
34_L120_Y2.5401.00
20_I44_L2.4851.00
186_N217_N2.4691.00
23_A35_A2.1771.00
47_T154_S2.0501.00
144_D180_R2.0401.00
28_H246_D2.0331.00
19_T35_A2.0111.00
220_A223_R2.0111.00
18_N183_L1.9541.00
32_Q121_D1.9531.00
188_N217_N1.9381.00
25_A232_F1.9321.00
6_I22_I1.8741.00
25_A249_A1.8261.00
79_A84_D1.8241.00
26_L124_L1.8171.00
183_L248_V1.8121.00
201_W205_T1.7881.00
200_A204_D1.7861.00
46_N157_L1.7711.00
29_R246_D1.6881.00
3_S125_I1.6851.00
184_I199_I1.6841.00
20_I47_T1.6821.00
194_E197_D1.6771.00
31_H121_D1.6571.00
144_D181_A1.6241.00
38_A138_V1.6221.00
27_A83_F1.6181.00
23_A124_L1.5961.00
5_A127_A1.5941.00
213_F251_T1.5831.00
218_R241_M1.5741.00
72_D75_D1.5141.00
6_I146_I1.4891.00
229_G234_E1.4691.00
20_I48_L1.4631.00
213_F248_V1.4561.00
38_A125_I1.4511.00
22_I252_L1.4041.00
187_V214_E1.3891.00
202_F206_F1.3871.00
219_A223_R1.3751.00
145_I166_I1.3661.00
27_A82_E1.3651.00
108_Q111_G1.3631.00
135_N138_V1.3551.00
43_Y158_A1.3521.00
7_S162_L1.3501.00
60_S63_D1.3431.00
14_G185_S1.3421.00
74_A119_D1.3341.00
189_Y199_I1.3111.00
48_L83_F1.3111.00
200_A214_E1.3041.00
212_V251_T1.2661.00
62_Y66_K1.2621.00
50_F85_V1.2541.00
144_D178_R1.2501.00
243_T246_D1.2481.00
6_I19_T1.2381.00
152_D155_S1.2371.00
146_I183_L1.2351.00
220_A235_D1.2211.00
23_A44_L1.2211.00
195_Q198_A1.2161.00
26_L33_V1.2141.00
151_A184_I1.2111.00
18_N185_S1.2101.00
75_D78_V1.1951.00
201_W204_D1.1901.00
195_Q199_I1.1831.00
59_P63_D1.1821.00
215_V241_M1.1771.00
22_I249_A1.1751.00
134_I138_V1.1711.00
247_D250_A1.1611.00
34_L123_V1.1541.00
71_H75_D1.1471.00
211_P214_E1.1421.00
102_S106_P1.1331.00
7_S127_A1.1321.00
24_G28_H1.1321.00
223_R227_A1.1311.00
90_I161_H1.1211.00
16_T47_T1.1111.00
38_A61_L1.1041.00
221_I241_M1.1041.00
246_D250_A1.0981.00
43_Y154_S1.0941.00
76_L79_A1.0931.00
152_D222_K1.0841.00
73_A86_L1.0601.00
40_P134_I1.0491.00
71_H76_L1.0421.00
85_V90_I1.0401.00
16_T44_L1.0381.00
77_V80_H1.0271.00
25_A29_R1.0231.00
160_E205_T1.0211.00
18_N22_I1.0171.00
247_D251_T1.0171.00
238_E242_T1.0151.00
193_N196_A1.0151.00
63_D66_K1.0141.00
109_R113_V1.0131.00
244_V247_D1.0101.00
229_G233_G1.0091.00
21_N24_G1.0041.00
133_P138_V0.9901.00
154_S225_L0.9881.00
110_F113_V0.9821.00
42_G45_T0.9721.00
63_D68_P0.9641.00
240_D243_T0.9621.00
23_A83_F0.9611.00
248_V252_L0.9601.00
194_E199_I0.9571.00
21_N232_F0.9531.00
36_I125_I0.9451.00
73_A76_L0.9361.00
3_S123_V0.9341.00
113_V116_Q0.9331.00
72_D76_L0.9321.00
147_I159_I0.9321.00
32_Q119_D0.9291.00
100_I103_G0.9281.00
232_F246_D0.9271.00
26_L249_A0.9201.00
25_A246_D0.9101.00
133_P140_L0.9081.00
48_L85_V0.9071.00
36_I123_V0.9071.00
148_P185_S0.9041.00
25_A28_H0.9021.00
199_I203_E0.9021.00
200_A203_E0.9011.00
185_S245_Y0.8991.00
227_A234_E0.8971.00
101_A105_R0.8861.00
4_F122_Y0.8851.00
218_R238_E0.8811.00
6_I18_N0.8781.00
241_M244_V0.8721.00
96_E132_G0.8681.00
236_A242_T0.8661.00
111_G115_D0.8631.00
4_F252_L0.8591.00
17_T221_I0.8591.00
127_A138_V0.8571.00
242_T246_D0.8511.00
102_S105_R0.8481.00
74_A78_V0.8411.00
17_T225_L0.8401.00
28_H233_G0.8401.00
41_Q132_G0.8281.00
164_N167_E0.8261.00
97_Q100_I0.8231.00
108_Q112_D0.8221.00
240_D244_V0.8211.00
61_L64_A0.8191.00
218_R240_D0.8161.00
3_S118_Q0.8121.00
192_D196_A0.8061.00
24_G233_G0.8041.00
203_E214_E0.8041.00
42_G88_A0.8011.00
76_L80_H0.7991.00
112_D116_Q0.7931.00
94_Q97_Q0.7921.00
151_A195_Q0.7901.00
6_I124_L0.7891.00
21_N230_S0.7891.00
74_A77_V0.7871.00
24_G232_F0.7801.00
206_F209_R0.7801.00
18_N215_V0.7771.00
147_I162_L0.7761.00
33_V122_Y0.7701.00
137_N140_L0.7681.00
199_I214_E0.7671.00
95_L99_L0.7661.00
235_D238_E0.7631.00
103_G106_P0.7581.00
215_V244_V0.7581.00
59_P71_H0.7551.00
184_I202_F0.7471.00
75_D79_A0.7471.00
10_K13_V0.7461.00
15_K129_P0.7461.00
63_D67_T0.7461.00
190_P198_A0.7441.00
188_N198_A0.7441.00
64_A67_T0.7421.00
181_A211_P0.7421.00
76_L86_L0.7391.00
170_E178_R0.7391.00
120_Y123_V0.7361.00
13_V155_S0.7351.00
73_A77_V0.7351.00
74_A116_Q0.7341.00
194_E198_A0.7311.00
64_A113_V0.7281.00
135_N139_L0.7251.00
46_N153_D0.7201.00
184_I187_V0.7191.00
35_A48_L0.7121.00
9_Q165_Q0.7101.00
7_S135_N0.7091.00
232_F242_T0.7051.00
151_A187_V0.7041.00
4_F144_D0.7011.00
18_N148_P0.6971.00
19_T44_L0.6961.00
147_I163_L0.6931.00
8_Q13_V0.6911.00
33_V124_L0.6901.00
243_T247_D0.6901.00
150_E155_S0.6881.00
25_A245_Y0.6881.00
231_I242_T0.6861.00
84_D87_P0.6861.00
28_H232_F0.6861.00
192_D198_A0.6851.00
101_A104_R0.6821.00
99_L103_G0.6691.00
24_G83_F0.6681.00
113_V117_L0.6661.00
133_P136_D0.6611.00
97_Q133_P0.6571.00
43_Y157_L0.6571.00
38_A134_I0.6531.00
160_E164_N0.6531.00
133_P137_N0.6501.00
64_A68_P0.6481.00
216_R240_D0.6431.00
45_T87_P0.6401.00
136_D165_Q0.6391.00
149_V182_I0.6351.00
104_R108_Q0.6331.00
57_D63_D0.6331.00
34_L77_V0.6291.00
163_L167_E0.6291.00
61_L65_I0.6291.00
42_G89_N0.6271.00
75_D80_H0.6261.00
95_L98_D0.6241.00
45_T89_N0.6221.00
224_S231_I0.6201.00
10_K154_S0.6201.00
153_D157_L0.6191.00
118_Q143_E0.6191.00
71_H74_A0.6151.00
237_E243_T0.6141.00
77_V84_D0.6141.00
238_E241_M0.6131.00
3_S143_E0.6111.00
189_Y193_N0.6101.00
64_A76_L0.6081.00
38_A110_F0.6061.00
197_D200_A0.6061.00
167_E170_E0.6051.00
43_Y46_N0.6011.00
24_G230_S0.6011.00
231_I241_M0.6001.00
181_A212_V0.6001.00
33_V83_F0.6001.00
109_R114_L0.5971.00
224_S229_G0.5951.00
192_D199_I0.5931.00
106_P134_I0.5901.00
72_D80_H0.5891.00
205_T208_G0.5871.00
138_V142_A0.5861.00
184_I214_E0.5861.00
146_I252_L0.5821.00
32_Q84_D0.5821.00
204_D207_D0.5821.00
94_Q98_D0.5791.00
202_F205_T0.5771.00
24_G27_A0.5751.00
156_V202_F0.5741.00
135_N140_L0.5721.00
164_N168_S0.5711.00
193_N197_D0.5711.00
124_L252_L0.5701.00
62_Y98_D0.5691.00
87_P90_I0.5671.00
20_I35_A0.5661.00
222_K226_G0.5641.00
21_N231_I0.5611.00
127_A135_N0.5591.00
58_P61_L0.5571.00
149_V159_I0.5551.00
100_I106_P0.5541.00
81_A84_D0.5491.00
215_V248_V0.5491.00
27_A33_V0.5471.00
160_E206_F0.5451.00
147_I179_E0.5451.00
62_Y65_I0.5441.00
219_A222_K0.5401.00
33_V121_D0.5371.00
236_A243_T0.5371.00
57_D61_L0.5351.00
109_R112_D0.5341.00
4_F124_L0.5331.00
22_I248_V0.5321.00
221_I225_L0.5301.00
114_L141_A0.5281.00
223_R234_E0.5281.00
110_F114_L0.5251.00
188_N219_A0.5251.00
86_L117_L0.5221.00
32_Q120_Y0.5221.00
91_D94_Q0.5211.00
224_S234_E0.5201.00
156_V160_E0.5191.00
35_A124_L0.5181.00
41_Q129_P0.5161.00
209_R251_T0.5151.00
30_G82_E0.5151.00
165_Q168_S0.5141.00
224_S230_S0.5131.00
44_L85_V0.5121.00
73_A117_L0.5121.00
80_H85_V0.5121.00
233_G236_A0.5101.00
36_I114_L0.5101.00
24_G81_A0.5101.00
197_D201_W0.5091.00
131_L135_N0.5081.00
52_E57_D0.5071.00
153_D226_G0.5051.00
34_L117_L0.5041.00
21_N245_Y0.5021.00
10_K15_K0.5021.00
72_D77_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1wcv1 2 0.9416 100 0.247 Contact Map
3pg5A 2 0.8872 100 0.258 Contact Map
4pfsA 1 0.9066 100 0.26 Contact Map
2ozeA 2 0.9767 100 0.29 Contact Map
3ez2A 2 0.9844 100 0.3 Contact Map
1g3qA 1 0.9027 100 0.304 Contact Map
4rz3A 2 0.9105 100 0.305 Contact Map
1hyqA 1 0.8911 100 0.307 Contact Map
3ez9A 2 0.821 100 0.31 Contact Map
3ea0A 2 0.9027 100 0.315 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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