GREMLIN Database
O51969 - SojB
UniProt: O51969 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 254 (235)
Sequences: 18088 (11799)
Seq/√Len: 769.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
86_D122_Y3.8711.00
215_R242_R3.8341.00
20_A126_I3.7421.00
30_R248_A3.2561.00
32_H124_Y3.2511.00
27_L124_Y3.1331.00
19_I243_F2.8861.00
229_S232_G2.8631.00
152_L188_R2.8101.00
3_H146_N2.7841.00
6_T144_C2.7661.00
35_L122_Y2.6711.00
36_F45_G2.6461.00
188_R216_N2.5111.00
21_I45_G2.5061.00
24_A36_F2.2011.00
146_N182_I2.1471.00
33_D123_D2.1231.00
48_G156_A2.1091.00
219_G222_R2.0951.00
26_A231_F2.0551.00
29_D244_Q1.9921.00
7_V23_V1.9841.00
190_E216_N1.9781.00
20_A36_F1.9291.00
19_I185_V1.9261.00
30_R244_Q1.8761.00
27_L126_I1.8281.00
26_A247_A1.8241.00
80_R86_D1.8001.00
75_I121_D1.7861.00
47_I159_H1.7821.00
185_V246_I1.7591.00
186_A199_L1.7571.00
39_L140_A1.7231.00
21_I48_G1.7141.00
201_W205_Q1.6911.00
6_T129_A1.6881.00
4_R127_I1.6871.00
200_E204_E1.6781.00
32_H123_D1.6681.00
24_A126_I1.6621.00
28_A85_F1.6081.00
202_F206_Y1.5951.00
146_N183_G1.5781.00
217_R239_M1.5701.00
199_L203_D1.5591.00
21_I49_L1.5361.00
212_W249_H1.5111.00
7_V148_L1.5041.00
61_S64_D1.4911.00
15_G187_N1.4781.00
228_T233_H1.4281.00
200_E213_R1.4121.00
212_W246_I1.4091.00
27_L34_V1.3991.00
39_L127_I1.3981.00
218_V222_R1.3771.00
44_N160_A1.3641.00
189_I213_R1.3561.00
49_L85_F1.3561.00
147_V168_V1.3431.00
8_A164_L1.3371.00
148_L185_V1.3301.00
28_A84_E1.3181.00
23_V250_L1.3161.00
60_I64_D1.3121.00
3_H145_R1.3071.00
154_E157_S1.3051.00
153_P186_A1.2931.00
39_L62_L1.2911.00
7_V20_A1.2801.00
241_E244_Q1.2681.00
222_R226_N1.2681.00
77_A80_R1.2601.00
19_I187_N1.2551.00
237_T240_D1.2541.00
146_N180_D1.2491.00
214_I239_M1.2441.00
219_G234_S1.2391.00
35_L125_I1.2331.00
24_A45_G1.2151.00
51_L87_V1.2021.00
191_V194_E1.1961.00
17_T48_G1.1951.00
211_L249_H1.1851.00
17_T45_G1.1791.00
8_A129_A1.1761.00
245_A249_H1.1661.00
197_R200_E1.1641.00
26_A30_R1.1571.00
92_I163_I1.1531.00
67_T71_A1.1511.00
154_E221_K1.1471.00
63_Y67_T1.1391.00
228_T232_G1.1331.00
23_V247_A1.1291.00
162_D205_Q1.1251.00
245_A248_A1.1141.00
201_W204_E1.1141.00
106_R109_E1.0941.00
109_E112_W1.0931.00
244_Q248_A1.0921.00
242_R245_A1.0921.00
197_R201_W1.0871.00
187_N243_F1.0711.00
19_I23_V1.0661.00
22_N25_G1.0641.00
98_E134_G1.0591.00
220_I239_M1.0431.00
44_N156_A1.0411.00
210_P213_R1.0341.00
25_G29_D1.0311.00
97_A100_E1.0301.00
41_A136_L1.0261.00
217_R237_T1.0231.00
77_A81_S1.0151.00
33_D121_D1.0141.00
238_D241_E1.0101.00
37_V127_I1.0021.00
156_A224_W0.9951.00
43_G46_T0.9851.00
114_A117_E0.9811.00
112_W116_D0.9801.00
24_A85_F0.9691.00
86_D120_A0.9671.00
82_H232_G0.9571.00
198_I201_W0.9551.00
4_R125_I0.9541.00
103_T107_G0.9461.00
26_A29_D0.9441.00
77_A88_L0.9401.00
5_L124_Y0.9361.00
18_T220_I0.9281.00
166_G169_D0.9271.00
129_A140_A0.9261.00
149_I161_L0.9121.00
27_L247_A0.9021.00
22_N231_F0.8981.00
209_L249_H0.8961.00
200_E203_D0.8901.00
5_L250_L0.8871.00
226_N233_H0.8871.00
62_L65_I0.8851.00
49_L87_V0.8851.00
150_P187_N0.8831.00
239_M242_R0.8761.00
87_V92_I0.8731.00
231_F244_Q0.8731.00
4_R119_H0.8651.00
75_I78_V0.8641.00
26_A244_Q0.8631.00
34_V124_Y0.8561.00
42_Q134_G0.8561.00
149_I164_L0.8541.00
238_D242_R0.8511.00
18_T224_W0.8511.00
7_V19_I0.8471.00
195_A198_I0.8471.00
153_P189_I0.8471.00
217_R238_D0.8451.00
246_I250_L0.8431.00
235_E240_D0.8401.00
75_I81_S0.8391.00
96_S99_S0.8321.00
8_A137_T0.8301.00
29_D232_G0.8211.00
64_D71_A0.8211.00
110_R114_A0.8181.00
230_V240_D0.8161.00
203_D213_R0.8141.00
78_V81_S0.8131.00
64_D69_L0.8121.00
234_S237_T0.7931.00
25_G231_F0.7921.00
43_G90_S0.7921.00
110_R113_M0.7891.00
152_L157_S0.7891.00
149_I165_F0.7881.00
198_I203_D0.7881.00
183_G210_P0.7861.00
37_V125_I0.7861.00
86_D89_P0.7781.00
241_E245_A0.7781.00
104_A108_R0.7741.00
236_T241_E0.7731.00
111_L114_A0.7731.00
5_L146_N0.7681.00
16_K131_P0.7681.00
214_I242_R0.7631.00
113_M117_E0.7631.00
65_I72_Q0.7581.00
196_D200_E0.7551.00
162_D166_G0.7531.00
140_A144_C0.7531.00
25_G232_G0.7481.00
122_Y125_I0.7381.00
198_I206_Y0.7361.00
65_I114_A0.7331.00
147_V179_I0.7331.00
75_I79_I0.7291.00
114_A118_L0.7271.00
68_D71_A0.7261.00
3_H182_I0.7221.00
7_V126_I0.7221.00
153_P195_A0.7191.00
64_D67_T0.7131.00
22_N229_S0.7091.00
64_D70_D0.7071.00
165_F169_D0.7071.00
231_F240_D0.7061.00
47_I155_E0.7051.00
14_V157_S0.7011.00
97_A101_L0.6981.00
199_L213_R0.6971.00
19_I150_P0.6971.00
186_A189_I0.6961.00
199_L202_F0.6961.00
29_D231_F0.6941.00
112_W115_L0.6941.00
195_A202_F0.6941.00
235_E241_E0.6911.00
10_E167_H0.6911.00
34_V126_I0.6901.00
5_L182_I0.6871.00
78_V86_D0.6841.00
81_S87_V0.6811.00
189_I196_D0.6791.00
104_A110_R0.6791.00
19_I214_I0.6791.00
151_A199_L0.6741.00
36_F49_L0.6721.00
11_K156_A0.6701.00
155_E159_H0.6661.00
166_G170_T0.6651.00
11_K14_V0.6651.00
203_D211_L0.6641.00
44_N159_H0.6591.00
138_D167_H0.6581.00
9_N14_V0.6571.00
196_D203_D0.6541.00
69_L72_Q0.6521.00
46_T89_P0.6511.00
82_H85_F0.6501.00
129_A137_T0.6501.00
11_K16_K0.6451.00
25_G229_S0.6431.00
195_A205_Q0.6421.00
172_E180_D0.6411.00
71_A75_I0.6401.00
60_I70_D0.6391.00
215_R238_D0.6361.00
65_I77_A0.6321.00
63_Y100_E0.6321.00
109_E113_M0.6301.00
240_D244_Q0.6301.00
186_A213_R0.6291.00
35_L78_V0.6261.00
141_L147_V0.6241.00
186_A202_F0.6231.00
195_A199_L0.6161.00
25_G85_F0.6141.00
95_F98_E0.6131.00
230_V239_M0.6121.00
44_N47_I0.6111.00
198_I202_F0.6101.00
33_D122_Y0.6091.00
93_D96_S0.6081.00
22_N243_F0.6051.00
78_V88_L0.6031.00
202_F205_Q0.6001.00
103_T106_R0.5991.00
4_R145_R0.5981.00
3_H32_H0.5981.00
83_E86_D0.5971.00
108_R139_N0.5961.00
223_A230_V0.5931.00
26_A243_F0.5931.00
67_T70_D0.5901.00
71_A76_D0.5901.00
43_G91_H0.5871.00
107_G136_L0.5861.00
39_L136_L0.5841.00
39_L111_L0.5821.00
116_D119_H0.5781.00
42_Q131_P0.5781.00
151_A184_L0.5761.00
66_L69_L0.5761.00
76_D79_I0.5751.00
218_V221_K0.5751.00
134_G137_T0.5741.00
223_A233_H0.5741.00
119_H145_R0.5741.00
20_A45_G0.5731.00
105_M108_R0.5711.00
169_D172_E0.5711.00
34_V85_F0.5711.00
99_S135_L0.5691.00
8_A141_L0.5661.00
62_L66_L0.5631.00
88_L92_I0.5611.00
68_D72_Q0.5601.00
223_A228_T0.5591.00
183_G211_L0.5591.00
135_L138_D0.5591.00
65_I68_D0.5571.00
183_G209_L0.5561.00
219_G237_T0.5551.00
64_D68_D0.5541.00
70_D77_A0.5521.00
163_I166_G0.5511.00
8_A147_V0.5491.00
126_I250_L0.5451.00
194_E197_R0.5451.00
31_G84_E0.5421.00
75_I80_R0.5411.00
23_V246_I0.5401.00
239_M243_F0.5391.00
76_D80_R0.5391.00
119_H125_I0.5391.00
115_L143_A0.5391.00
28_A34_V0.5381.00
34_V123_D0.5371.00
111_L115_L0.5371.00
46_T91_H0.5321.00
25_G83_E0.5311.00
96_S100_E0.5291.00
221_K224_W0.5251.00
155_E225_A0.5251.00
190_E218_V0.5251.00
222_R233_H0.5241.00
148_L182_I0.5241.00
76_D81_S0.5231.00
25_G28_A0.5231.00
21_I36_F0.5191.00
23_V148_L0.5191.00
106_R113_M0.5171.00
48_G224_W0.5161.00
196_D202_F0.5161.00
22_N230_V0.5151.00
221_K225_A0.5151.00
72_Q75_I0.5151.00
133_L137_T0.5141.00
5_L126_I0.5141.00
139_N142_L0.5101.00
230_V233_H0.5101.00
193_G218_V0.5091.00
35_L118_L0.5071.00
84_E88_L0.5041.00
223_A229_S0.5031.00
198_I205_Q0.5021.00
86_D121_D0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pfsA 1 0.9134 100 0.235 Contact Map
3pg5A 2 0.8858 100 0.268 Contact Map
1g3qA 1 0.9252 100 0.27 Contact Map
1hyqA 1 0.9094 100 0.272 Contact Map
1wcv1 2 0.9449 100 0.273 Contact Map
3ea0A 2 0.9252 100 0.276 Contact Map
4rz3A 2 0.9331 100 0.282 Contact Map
2ozeA 2 0.9803 100 0.289 Contact Map
3ez2A 2 0.9961 100 0.296 Contact Map
3ez9A 2 0.8346 100 0.297 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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