GVPO1 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

GVPO1 - Protein GvpO 1

UniProt:	O51968	Sequences: MADPANDRSEREEGGEDDETPPASDGNPSPSANSFTLSNAQTRAREAAQDLLEHQFEGMIKAESNDEGWRTVVEVVERNAVPDTQDIIGRYEITLDGTGDVTGYELLERYRRGDMKEEL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	119 (100)
Sequences:	210 (168)
Seq/√Len:	16.8

HALSA - GVPO1 GVPO2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
108_E	116_K	2.927	0.98
78_R	86_D	2.538	0.96
41_Q	71_T	2.471	0.95
60_I	86_D	2.463	0.95
52_L	105_E	2.330	0.93
81_V	85_Q	2.113	0.89
86_D	116_K	1.898	0.83
17_D	20_T	1.866	0.82
45_R	102_T	1.832	0.81
41_Q	58_G	1.815	0.80
88_I	100_D	1.813	0.80
44_A	101_V	1.788	0.79
58_G	70_R	1.781	0.79
87_I	115_M	1.735	0.77
41_Q	52_L	1.731	0.77
57_E	64_S	1.691	0.75
52_L	71_T	1.689	0.75
58_G	71_T	1.667	0.74
74_E	110_Y	1.645	0.73
71_T	74_E	1.630	0.72
48_A	90_R	1.620	0.72
70_R	94_T	1.574	0.70
80_A	89_G	1.566	0.69
39_N	66_D	1.546	0.68
111_R	114_D	1.542	0.68
72_V	90_R	1.445	0.63
50_D	74_E	1.416	0.61
78_R	85_Q	1.412	0.61
25_D	31_S	1.366	0.58
33_N	36_T	1.358	0.58
42_T	50_D	1.347	0.57
86_D	90_R	1.336	0.57
22_P	25_D	1.333	0.57
22_P	26_G	1.300	0.55
54_H	111_R	1.299	0.55
60_I	116_K	1.285	0.54
71_T	114_D	1.284	0.54
48_A	86_D	1.275	0.53
85_Q	111_R	1.274	0.53
105_E	115_M	1.269	0.53
58_G	111_R	1.252	0.52
37_L	80_A	1.203	0.49
84_T	104_Y	1.200	0.49
18_D	24_S	1.196	0.48
18_D	22_P	1.180	0.47
62_A	111_R	1.162	0.46
92_E	105_E	1.153	0.46
57_E	76_V	1.148	0.46
19_E	67_E	1.141	0.45
19_E	29_S	1.129	0.44
40_A	73_V	1.097	0.43
19_E	26_G	1.090	0.42
89_G	106_L	1.045	0.40
56_F	92_E	1.040	0.39
61_K	90_R	1.014	0.38
23_A	98_T	1.010	0.38
89_G	93_I	0.997	0.37
40_A	44_A	0.980	0.36
83_D	113_G	0.972	0.36
29_S	97_G	0.972	0.36
22_P	32_A	0.955	0.35
78_R	90_R	0.931	0.33
47_A	89_G	0.926	0.33
54_H	58_G	0.925	0.33
71_T	111_R	0.895	0.31
71_T	87_I	0.891	0.31
53_E	95_L	0.878	0.31
74_E	114_D	0.878	0.31
46_E	97_G	0.872	0.30
61_K	94_T	0.871	0.30
17_D	22_P	0.864	0.30
64_S	88_I	0.838	0.29
80_A	106_L	0.817	0.28
21_P	24_S	0.813	0.27
63_E	105_E	0.808	0.27
87_I	111_R	0.797	0.27
57_E	83_D	0.793	0.26
23_A	27_N	0.785	0.26
80_A	101_V	0.784	0.26
73_V	108_E	0.783	0.26
33_N	57_E	0.778	0.26
24_S	98_T	0.767	0.25
33_N	98_T	0.754	0.25
26_G	30_P	0.744	0.24
102_T	114_D	0.741	0.24
62_A	72_V	0.734	0.24
87_I	105_E	0.726	0.23
36_T	83_D	0.722	0.23
18_D	66_D	0.718	0.23
54_H	71_T	0.716	0.23
101_V	108_E	0.714	0.23
42_T	59_M	0.710	0.23
46_E	55_Q	0.709	0.23
52_L	111_R	0.708	0.23
51_L	73_V	0.707	0.23
61_K	74_E	0.703	0.22
103_G	107_L	0.703	0.22
42_T	75_V	0.702	0.22
56_F	85_Q	0.699	0.22
96_D	113_G	0.687	0.22
53_E	68_G	0.678	0.21
28_P	66_D	0.678	0.21
25_D	32_A	0.672	0.21
24_S	103_G	0.669	0.21
63_E	87_I	0.652	0.20
20_T	25_D	0.649	0.20
27_N	43_R	0.646	0.20
64_S	115_M	0.644	0.20
48_A	93_I	0.641	0.20
73_V	90_R	0.640	0.20
88_I	113_G	0.638	0.20
72_V	114_D	0.634	0.20
19_E	24_S	0.633	0.20
60_I	90_R	0.631	0.20
38_S	81_V	0.630	0.20
41_Q	85_Q	0.627	0.20
26_G	46_E	0.627	0.20
61_K	71_T	0.626	0.19
37_L	93_I	0.623	0.19
22_P	96_D	0.610	0.19
80_A	90_R	0.606	0.19
22_P	28_P	0.605	0.19
37_L	40_A	0.589	0.18
79_N	84_T	0.586	0.18
27_N	97_G	0.584	0.18
66_D	100_D	0.582	0.18
21_P	28_P	0.582	0.18
84_T	87_I	0.577	0.18
90_R	116_K	0.572	0.18
20_T	67_E	0.562	0.17
54_H	87_I	0.550	0.17
41_Q	78_R	0.549	0.17
19_E	30_P	0.548	0.17
57_E	88_I	0.546	0.17
44_A	63_E	0.544	0.17
31_S	66_D	0.541	0.16
18_D	30_P	0.541	0.16
80_A	85_Q	0.537	0.16
45_R	67_E	0.529	0.16
74_E	85_Q	0.520	0.16
47_A	50_D	0.518	0.16
39_N	107_L	0.518	0.16
24_S	66_D	0.516	0.16
101_V	116_K	0.515	0.16
105_E	114_D	0.514	0.16
32_A	98_T	0.510	0.15
48_A	87_I	0.507	0.15
52_L	63_E	0.505	0.15
79_N	107_L	0.505	0.15
63_E	81_V	0.500	0.15

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2glwA	1	0.2941	9.5	0.935	Contact Map
2km7A	1	0.2857	4.7	0.944	Contact Map
2ci2I	3	0.5378	4	0.946	Contact Map
4exrA	2	0.7647	3.9	0.946	Contact Map
2fggA	2	0.437	3.8	0.946	Contact Map
4hhjA	1	0.5042	3.7	0.947	Contact Map
3p2hA	1	0.6387	2.7	0.95	Contact Map
1xwrA	4	0.6639	2.4	0.951	Contact Map
4ffjA	2	0.7731	2	0.953	Contact Map
1x3lA	1	0.8739	2	0.953	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0057 seconds.