GREMLIN Database
O51962 - SojA
UniProt: O51962 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 139 (111)
Sequences: 612 (352)
Seq/√Len: 33.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
119_L133_I4.9891.00
70_A130_V3.1611.00
125_Q131_A2.3330.99
63_I87_L2.3220.99
50_G135_N2.1530.99
62_S78_A2.1310.99
25_V28_S2.1090.99
63_I90_K2.0960.98
103_A106_D1.9980.98
96_Q101_E1.9870.98
81_A104_L1.9760.98
126_G132_K1.9000.97
21_Y25_V1.8790.97
122_L133_I1.8760.97
104_L133_I1.8510.97
47_I65_L1.7080.95
85_G136_N1.6660.94
75_D81_A1.6510.94
49_V65_L1.6040.93
125_Q129_R1.6020.93
56_V87_L1.5930.92
22_T26_C1.5870.92
107_V122_L1.5480.91
21_Y31_S1.5040.90
102_Y106_D1.4770.89
48_D132_K1.4460.88
56_V85_G1.4310.87
23_R27_Y1.4290.87
112_G119_L1.3990.86
67_G86_G1.3410.84
88_T93_H1.2890.81
37_T68_A1.2870.81
100_G138_Q1.2740.81
52_Q86_G1.2600.80
38_R74_H1.2510.79
52_Q64_N1.2450.79
26_C29_N1.2270.78
113_Q119_L1.2210.78
69_L135_N1.2140.77
24_N28_S1.1940.76
57_G90_K1.1760.75
21_Y28_S1.1570.74
46_R75_D1.1560.74
65_L81_A1.1550.74
37_T42_G1.1420.73
65_L96_Q1.1380.72
46_R123_V1.1380.72
113_Q133_I1.1280.72
24_N30_G1.1210.71
85_G88_T1.1190.71
24_N27_Y1.1160.71
25_V81_A1.1130.71
106_D122_L1.1050.70
50_G59_T1.0990.70
65_L111_M1.0770.68
50_G128_G1.0440.66
51_M84_Q1.0430.66
22_T25_V1.0370.65
64_N68_A1.0310.65
40_T46_R1.0180.64
37_T72_R1.0050.63
50_G91_L0.9970.62
94_R101_E0.9690.60
62_S72_R0.9500.58
97_Y103_A0.9430.58
63_I134_G0.9400.57
71_D126_G0.9390.57
23_R97_Y0.9290.57
94_R121_E0.9280.56
28_S81_A0.9050.55
21_Y75_D0.8800.52
47_I132_K0.8790.52
40_T43_G0.8730.52
101_E138_Q0.8720.52
48_D110_E0.8710.52
33_N119_L0.8630.51
37_T65_L0.8610.51
57_G63_I0.8560.50
112_G122_L0.8250.48
40_T74_H0.8230.48
89_L136_N0.8150.47
64_N90_K0.8140.47
25_V75_D0.8090.47
30_G124_V0.7990.46
41_E57_G0.7960.45
111_M123_V0.7950.45
25_V30_G0.7940.45
78_A106_D0.7910.45
26_C107_V0.7860.45
79_V113_Q0.7810.44
78_A90_K0.7790.44
101_E124_V0.7770.44
42_G124_V0.7720.43
64_N105_Y0.7670.43
78_A87_L0.7660.43
60_T75_D0.7630.43
76_V121_E0.7510.42
35_Y124_V0.7450.41
77_L123_V0.7430.41
66_A90_K0.7420.41
60_T136_N0.7350.40
57_G88_T0.7320.40
29_N113_Q0.7280.40
85_G135_N0.7200.39
88_T136_N0.7190.39
104_L119_L0.7130.39
61_T125_Q0.7080.38
83_P89_L0.6960.37
24_N31_S0.6920.37
97_Y104_L0.6880.37
41_E45_M0.6850.36
63_I105_Y0.6840.36
96_Q120_D0.6820.36
109_S123_V0.6810.36
47_I81_A0.6790.36
85_G89_L0.6790.36
106_D135_N0.6750.36
60_T85_G0.6620.35
105_Y121_E0.6620.35
23_R28_S0.6500.34
28_S31_S0.6450.33
34_P112_G0.6340.33
64_N86_G0.6340.33
66_A78_A0.6280.32
52_Q95_E0.6220.32
110_E128_G0.6140.31
86_G127_A0.6110.31
56_V90_K0.6110.31
49_V63_I0.6110.31
65_L108_L0.6100.31
63_I91_L0.6060.31
35_Y109_S0.6030.30
45_M64_N0.6020.30
32_K135_N0.6000.30
44_S109_S0.5900.29
81_A109_S0.5890.29
76_V92_G0.5890.29
40_T138_Q0.5870.29
50_G79_V0.5780.29
107_V113_Q0.5770.29
74_H88_T0.5750.28
80_D84_Q0.5690.28
27_Y31_S0.5680.28
38_R88_T0.5600.27
45_M56_V0.5600.27
86_G95_E0.5560.27
27_Y40_T0.5550.27
64_N67_G0.5490.27
70_A105_Y0.5470.27
83_P107_V0.5470.27
62_S120_D0.5430.26
24_N62_S0.5410.26
48_D101_E0.5310.26
119_L131_A0.5310.26
22_T128_G0.5300.25
78_A83_P0.5290.25
123_V131_A0.5290.25
49_V57_G0.5280.25
71_D113_Q0.5270.25
24_N104_L0.5230.25
38_R71_D0.5220.25
76_V135_N0.5190.25
112_G126_G0.5160.25
94_R108_L0.5120.24
27_Y37_T0.5110.24
50_G87_L0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ez2A 2 0.9928 99.9 0.464 Contact Map
3ez9A 2 0.8705 99.9 0.466 Contact Map
4pfsA 1 0.6475 99.9 0.5 Contact Map
3pg5A 2 0.6835 99.9 0.519 Contact Map
2ynmA 2 0.6475 99.9 0.537 Contact Map
1wcv1 2 0.6115 99.9 0.541 Contact Map
3fwyA 2 0.6547 99.9 0.543 Contact Map
4rz3A 2 0.6259 99.9 0.544 Contact Map
3kjhA 2 0.6331 99.9 0.555 Contact Map
4wzaE 2 0.6547 99.9 0.555 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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