YTFR - ECOLI - GREMLIN Contacts

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YTFR - Uncharacterized ABC transporter ATP-binding protein YtfR

UniProt:	Q6BEX0	Sequences: MTTDQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGENGAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAHAQQLGIGTVYQEVNLLPNMSVADNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAIDLSAKVLILDEPTASLDTQEVELLFDLMRQLRDRGVSLIFVTHFLDQVYQVSDRITVLRNGSFVGCRETCELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTIAPFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIKGKPQNLRSPHQASVLGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQLGIRTPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCADGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12518
Length:	500 (490)
Sequences:	2451 (1776)
Seq/√Len:	80.2

ECOLI - YTFR MGLA YPHE ALSA XYLG ARAG LSRA RBSA
BACSU - YUFO RBSA YKPA YFMM
HALSA - Q9HR21
SULSO - Y2030 Y1893

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
65_T	72_A	4.760	1.00
36_E	214_R	3.804	1.00
26_D	222_S	3.747	1.00
14_G	27_N	3.707	1.00
123_E	140_R	3.615	1.00
69_E	165_K	3.438	1.00
127_T	131_A	3.404	1.00
316_T	323_P	3.365	1.00
38_M	216_T	3.196	1.00
121_E	125_R	3.153	1.00
262_K	265_A	3.057	1.00
457_V	468_Y	3.046	1.00
37_I	188_M	3.033	1.00
39_A	212_S	3.027	1.00
304_E	310_K	2.926	1.00
225_G	240_M	2.915	1.00
386_I	396_T	2.896	1.00
189_R	210_Q	2.884	1.00
303_A	458_I	2.797	1.00
18_F	23_K	2.757	1.00
125_R	128_E	2.739	1.00
228_E	231_E	2.726	1.00
422_Q	453_L	2.662	1.00
447_T	451_D	2.658	1.00
11_R	31_S	2.625	1.00
75_P	84_L	2.586	1.00
258_L	262_K	2.558	1.00
473_I	483_E	2.453	1.00
267_F	270_Y	2.430	1.00
320_K	422_Q	2.418	1.00
485_P	488_E	2.406	1.00
239_K	245_E	2.388	1.00
13_E	65_T	2.379	1.00
385_F	414_S	2.369	1.00
19_F	59_Y	2.366	1.00
14_G	29_D	2.343	1.00
489_L	493_A	2.333	1.00
384_R	388_Q	2.326	1.00
12_T	55_L	2.321	1.00
18_F	63_R	2.296	1.00
283_V	289_V	2.291	1.00
182_E	210_Q	2.264	1.00
359_I	391_I	2.253	1.00
124_K	128_E	2.235	1.00
350_I	361_L	2.229	1.00
262_K	266_A	2.222	1.00
261_D	265_A	2.199	1.00
482_A	497_A	2.191	1.00
12_T	15_L	2.184	1.00
373_I	378_Q	2.183	1.00
23_K	26_D	2.182	1.00
277_A	479_K	2.172	1.00
8_E	33_R	2.100	1.00
212_S	229_T	2.094	1.00
288_I	445_I	2.090	1.00
259_L	262_K	2.076	1.00
118_R	121_E	2.073	1.00
89_V	169_L	2.057	1.00
263_P	266_A	2.022	1.00
68_L	166_V	1.996	1.00
9_I	197_S	1.985	1.00
263_P	282_E	1.976	1.00
377_E	380_E	1.968	1.00
16_S	23_K	1.966	1.00
260_S	263_P	1.890	1.00
67_W	72_A	1.886	1.00
383_E	387_R	1.869	1.00
355_V	393_T	1.866	1.00
386_I	393_T	1.861	1.00
289_V	473_I	1.854	1.00
319_I	324_Q	1.848	1.00
260_S	265_A	1.846	1.00
132_S	194_R	1.843	1.00
141_E	145_R	1.781	1.00
11_R	67_W	1.777	1.00
13_E	67_W	1.769	1.00
128_E	132_S	1.748	1.00
262_K	267_F	1.737	1.00
8_E	31_S	1.734	1.00
258_L	265_A	1.733	1.00
259_L	266_A	1.692	1.00
233_P	236_E	1.685	1.00
327_R	331_Q	1.672	1.00
16_S	27_N	1.649	1.00
265_A	269_N	1.642	1.00
77_N	80_H	1.641	1.00
281_L	291_L	1.635	1.00
283_V	456_L	1.628	1.00
259_L	265_A	1.619	1.00
349_I	400_I	1.615	1.00
165_K	196_V	1.610	1.00
71_Q	84_L	1.609	1.00
101_V	137_L	1.599	1.00
102_A	123_E	1.590	1.00
138_D	141_E	1.581	1.00
264_V	267_F	1.580	1.00
305_V	312_A	1.573	1.00
14_G	63_R	1.568	1.00
52_I	88_T	1.562	1.00
260_S	264_V	1.561	1.00
486_L	489_L	1.561	1.00
15_L	54_A	1.556	1.00
192_R	213_D	1.554	1.00
281_L	473_I	1.545	0.99
262_K	270_Y	1.545	0.99
32_L	197_S	1.534	0.99
281_L	289_V	1.528	0.99
360_I	378_Q	1.528	0.99
95_L	143_L	1.523	0.99
490_S	493_A	1.517	0.99
356_R	397_E	1.506	0.99
258_L	261_D	1.502	0.99
484_I	497_A	1.500	0.99
352_A	401_E	1.494	0.99
472_V	489_L	1.493	0.99
259_L	264_V	1.492	0.99
258_L	264_V	1.489	0.99
132_S	190_Q	1.485	0.99
322_K	335_L	1.484	0.99
8_E	34_R	1.479	0.99
374_S	377_E	1.466	0.99
274_G	277_A	1.466	0.99
58_V	90_Y	1.460	0.99
216_T	223_F	1.454	0.99
426_L	445_I	1.451	0.99
258_L	266_A	1.450	0.99
412_L	415_R	1.447	0.99
76_K	80_H	1.446	0.99
466_V	489_L	1.445	0.99
189_R	192_R	1.441	0.99
232_L	236_E	1.441	0.99
209_Y	237_L	1.437	0.99
283_V	454_A	1.436	0.99
18_F	62_D	1.427	0.99
379_Q	397_E	1.415	0.99
265_A	316_T	1.412	0.99
127_T	139_V	1.406	0.99
20_P	394_P	1.401	0.99
209_Y	233_P	1.392	0.99
261_D	266_A	1.376	0.99
488_E	493_A	1.373	0.99
190_Q	194_R	1.360	0.99
285_P	454_A	1.355	0.99
96_L	107_I	1.341	0.99
283_V	423_F	1.338	0.98
266_A	278_P	1.338	0.98
185_F	211_V	1.337	0.98
302_T	475_M	1.334	0.98
445_I	457_V	1.327	0.98
32_L	166_V	1.310	0.98
300_T	342_E	1.310	0.98
120_K	124_K	1.304	0.98
131_A	136_S	1.303	0.98
290_G	469_A	1.303	0.98
206_D	234_Q	1.302	0.98
318_L	323_P	1.301	0.98
354_S	357_E	1.294	0.98
265_A	270_Y	1.281	0.98
20_P	23_K	1.280	0.98
142_P	145_R	1.278	0.98
143_L	154_V	1.273	0.98
266_A	282_E	1.273	0.98
265_A	268_K	1.266	0.98
10_L	68_L	1.263	0.98
169_L	198_L	1.262	0.98
445_I	468_Y	1.261	0.98
484_I	489_L	1.256	0.98
383_E	396_T	1.254	0.98
385_F	391_I	1.252	0.98
380_E	384_R	1.249	0.98
103_D	119_R	1.236	0.97
319_I	423_F	1.224	0.97
34_R	165_K	1.222	0.97
31_S	214_R	1.210	0.97
304_E	347_D	1.210	0.97
447_T	450_A	1.203	0.97
264_V	454_A	1.202	0.97
227_R	240_M	1.193	0.97
236_E	239_K	1.192	0.97
98_N	144_N	1.190	0.97
217_V	240_M	1.187	0.97
41_L	205_L	1.185	0.97
38_M	226_C	1.183	0.97
227_R	232_L	1.174	0.97
54_A	62_D	1.172	0.96
276_I	279_F	1.172	0.96
261_D	264_V	1.171	0.96
100_S	103_D	1.166	0.96
258_L	263_P	1.163	0.96
188_M	198_L	1.163	0.96
190_Q	193_D	1.160	0.96
264_V	269_N	1.145	0.96
29_D	223_F	1.139	0.96
276_I	305_V	1.138	0.96
8_E	11_R	1.135	0.96
465_L	469_A	1.117	0.95
260_S	266_A	1.113	0.95
27_N	222_S	1.112	0.95
261_D	270_Y	1.110	0.95
291_L	456_L	1.109	0.95
214_R	228_E	1.107	0.95
289_V	483_E	1.105	0.95
268_K	316_T	1.099	0.95
278_P	479_K	1.098	0.95
188_M	211_V	1.097	0.95
288_I	455_L	1.093	0.95
386_I	391_I	1.086	0.95
75_P	80_H	1.083	0.95
444_L	447_T	1.083	0.95
291_L	473_I	1.076	0.94
394_P	402_F	1.067	0.94
215_I	229_T	1.065	0.94
267_F	271_G	1.064	0.94
330_H	334_V	1.062	0.94
250_A	467_G	1.059	0.94
111_P	117_L	1.054	0.94
303_A	339_F	1.054	0.94
102_A	139_V	1.051	0.94
259_L	263_P	1.051	0.94
134_G	190_Q	1.049	0.94
340_C	426_L	1.048	0.94
261_D	269_N	1.046	0.93
16_S	63_R	1.044	0.93
258_L	267_F	1.043	0.93
147_S	150_M	1.043	0.93
355_V	411_V	1.041	0.93
393_T	398_Q	1.037	0.93
129_L	161_D	1.033	0.93
329_P	332_A	1.029	0.93
164_A	167_L	1.024	0.93
266_A	269_N	1.021	0.93
116_L	372_P	1.021	0.93
121_E	124_K	1.019	0.93
208_V	229_T	1.018	0.92
433_I	441_I	1.017	0.92
10_L	55_L	1.014	0.92
133_Y	157_C	1.013	0.92
73_I	84_L	1.013	0.92
111_P	122_M	1.013	0.92
32_L	199_I	1.009	0.92
400_I	411_V	1.006	0.92
52_I	201_V	1.003	0.92
182_E	186_D	0.998	0.92
328_S	331_Q	0.998	0.92
473_I	480_Q	0.997	0.92
183_L	186_D	0.996	0.92
266_A	318_L	0.995	0.92
295_L	460_S	0.995	0.92
469_A	486_L	0.994	0.92
188_M	200_F	0.991	0.91
264_V	281_L	0.989	0.91
33_R	214_R	0.988	0.91
54_A	61_A	0.987	0.91
471_R	483_E	0.986	0.91
105_L	154_V	0.986	0.91
112_K	115_G	0.983	0.91
326_L	331_Q	0.980	0.91
303_A	425_I	0.967	0.90
28_V	218_L	0.966	0.90
345_K	351_A	0.963	0.90
263_P	270_Y	0.960	0.90
289_V	456_L	0.960	0.90
292_A	465_L	0.960	0.90
216_T	226_C	0.954	0.90
148_V	174_A	0.950	0.90
262_K	269_N	0.945	0.89
493_A	497_A	0.943	0.89
290_G	465_L	0.943	0.89
442_I	467_G	0.938	0.89
105_L	126_A	0.936	0.89
209_Y	229_T	0.936	0.89
37_I	192_R	0.934	0.89
53_K	90_Y	0.932	0.89
34_R	69_E	0.928	0.89
287_E	471_R	0.927	0.88
135_F	153_I	0.924	0.88
260_S	282_E	0.923	0.88
493_A	496_N	0.922	0.88
369_W	372_P	0.920	0.88
56_T	88_T	0.919	0.88
34_R	197_S	0.916	0.88
356_R	378_Q	0.915	0.88
476_R	481_V	0.914	0.88
384_R	387_R	0.914	0.88
266_A	270_Y	0.911	0.88
258_L	269_N	0.911	0.88
253_R	450_A	0.910	0.88
236_E	240_M	0.908	0.87
155_A	158_R	0.908	0.87
474_I	494_I	0.894	0.87
209_Y	232_L	0.890	0.86
20_P	24_A	0.885	0.86
16_S	26_D	0.884	0.86
214_R	226_C	0.883	0.86
420_R	451_D	0.882	0.86
288_I	468_Y	0.879	0.86
49_S	53_K	0.879	0.86
9_I	68_L	0.878	0.86
486_L	493_A	0.877	0.86
105_L	161_D	0.874	0.85
285_P	422_Q	0.872	0.85
343_D	346_T	0.870	0.85
95_L	151_Q	0.869	0.85
279_F	480_Q	0.868	0.85
20_P	26_D	0.868	0.85
9_I	69_E	0.866	0.85
363_L	366_Q	0.864	0.85
9_I	166_V	0.864	0.85
363_L	418_L	0.862	0.85
80_H	83_Q	0.862	0.85
326_L	332_A	0.857	0.84
381_I	418_L	0.857	0.84
350_I	353_A	0.851	0.84
68_L	165_K	0.851	0.84
420_R	453_L	0.850	0.84
465_L	472_V	0.849	0.84
388_Q	447_T	0.849	0.84
25_L	54_A	0.849	0.84
261_D	267_F	0.846	0.83
445_I	455_L	0.846	0.83
27_N	63_R	0.845	0.83
302_T	306_I	0.845	0.83
97_P	151_Q	0.844	0.83
123_E	127_T	0.844	0.83
212_S	215_I	0.839	0.83
391_I	414_S	0.834	0.83
139_V	142_P	0.834	0.83
13_E	31_S	0.833	0.83
22_V	394_P	0.833	0.83
395_S	398_Q	0.831	0.82
421_P	426_L	0.831	0.82
263_P	318_L	0.830	0.82
259_L	267_F	0.828	0.82
66_I	75_P	0.826	0.82
260_S	284_R	0.824	0.82
355_V	394_P	0.817	0.81
428_E	460_S	0.814	0.81
17_K	62_D	0.811	0.81
262_K	285_P	0.811	0.81
338_G	424_L	0.808	0.81
93_V	175_S	0.805	0.80
75_P	81_A	0.804	0.80
341_P	347_D	0.804	0.80
362_A	419_T	0.804	0.80
223_F	226_C	0.801	0.80
281_L	456_L	0.799	0.80
30_F	38_M	0.798	0.80
285_P	320_K	0.795	0.79
369_W	381_I	0.793	0.79
351_A	400_I	0.791	0.79
484_I	488_E	0.789	0.79
101_V	141_E	0.789	0.79
10_L	166_V	0.787	0.79
481_V	497_A	0.787	0.79
112_K	118_R	0.786	0.79
343_D	431_R	0.784	0.79
101_V	146_F	0.780	0.78
445_I	449_C	0.778	0.78
55_L	66_I	0.778	0.78
484_I	493_A	0.778	0.78
355_V	403_L	0.777	0.78
356_R	379_Q	0.776	0.78
106_F	122_M	0.776	0.78
423_F	456_L	0.771	0.77
448_L	453_L	0.768	0.77
227_R	236_E	0.765	0.77
159_A	169_L	0.764	0.77
228_E	232_L	0.763	0.77
448_L	451_D	0.761	0.76
227_R	231_E	0.760	0.76
331_Q	335_L	0.759	0.76
189_R	193_D	0.757	0.76
263_P	268_K	0.757	0.76
383_E	386_I	0.755	0.76
209_Y	234_Q	0.753	0.76
128_E	131_A	0.753	0.76
235_I	496_N	0.752	0.76
120_K	376_K	0.748	0.75
68_L	86_I	0.746	0.75
268_K	313_D	0.746	0.75
405_G	409_Q	0.745	0.75
80_H	84_L	0.744	0.75
78_T	81_A	0.743	0.75
485_P	489_L	0.742	0.75
68_L	84_L	0.742	0.75
127_T	140_R	0.740	0.74
61_A	74_S	0.740	0.74
92_E	345_K	0.739	0.74
102_A	122_M	0.739	0.74
394_P	398_Q	0.738	0.74
41_L	237_L	0.737	0.74
484_I	494_I	0.737	0.74
359_I	382_A	0.735	0.74
93_V	174_A	0.734	0.74
399_P	402_F	0.734	0.74
149_A	152_Q	0.734	0.74
101_V	154_V	0.732	0.74
235_I	239_K	0.731	0.74
242_L	246_L	0.730	0.73
18_F	24_A	0.730	0.73
126_A	130_M	0.728	0.73
391_I	411_V	0.725	0.73
20_P	398_Q	0.725	0.73
30_F	197_S	0.723	0.73
8_E	13_E	0.720	0.72
79_A	83_Q	0.720	0.72
329_P	336_G	0.719	0.72
438_H	461_E	0.717	0.72
398_Q	402_F	0.717	0.72
400_I	412_L	0.716	0.72
126_A	139_V	0.716	0.72
366_Q	420_R	0.713	0.72
269_N	278_P	0.713	0.72
111_P	125_R	0.712	0.72
281_L	302_T	0.712	0.72
175_S	295_L	0.710	0.71
12_T	30_F	0.710	0.71
155_A	201_V	0.709	0.71
173_T	184_L	0.709	0.71
457_V	469_A	0.709	0.71
251_L	467_G	0.708	0.71
359_I	411_V	0.708	0.71
466_V	494_I	0.708	0.71
404_S	407_N	0.708	0.71
463_E	491_V	0.707	0.71
129_L	133_Y	0.704	0.71
380_E	383_E	0.703	0.71
94_N	169_L	0.702	0.70
87_G	164_A	0.701	0.70
229_T	232_L	0.699	0.70
237_L	241_M	0.695	0.70
443_R	447_T	0.694	0.70
315_G	321_G	0.693	0.69
124_K	127_T	0.693	0.69
259_L	269_N	0.693	0.69
300_T	339_F	0.692	0.69
12_T	32_L	0.692	0.69
53_K	58_V	0.690	0.69
257_T	284_R	0.689	0.69
262_K	268_K	0.685	0.69
466_V	486_L	0.684	0.68
11_R	70_G	0.682	0.68
93_V	155_A	0.682	0.68
82_Q	162_L	0.681	0.68
31_S	67_W	0.679	0.68
95_L	154_V	0.677	0.68
177_D	180_E	0.675	0.67
269_N	314_S	0.674	0.67
60_H	74_S	0.674	0.67
257_T	260_S	0.672	0.67
324_Q	423_F	0.670	0.67
238_V	241_M	0.670	0.67
266_A	316_T	0.666	0.66
40_L	55_L	0.666	0.66
259_L	268_K	0.663	0.66
209_Y	212_S	0.663	0.66
208_V	215_I	0.662	0.66
484_I	487_A	0.661	0.66
102_A	111_P	0.660	0.66
184_L	188_M	0.659	0.66
304_E	309_I	0.659	0.66
413_L	441_I	0.656	0.65
347_D	412_L	0.656	0.65
455_L	468_Y	0.652	0.65
13_E	29_D	0.651	0.65
209_Y	215_I	0.651	0.65
93_V	150_M	0.651	0.65
217_V	225_G	0.650	0.65
300_T	427_D	0.650	0.65
427_D	460_S	0.648	0.64
127_T	138_D	0.642	0.64
393_T	403_L	0.641	0.63
56_T	89_V	0.640	0.63
181_V	204_F	0.639	0.63
338_G	421_P	0.638	0.63
100_S	142_P	0.637	0.63
408_Q	460_S	0.637	0.63
14_G	67_W	0.636	0.63
35_G	40_L	0.635	0.63
9_I	32_L	0.633	0.63
291_L	303_A	0.633	0.63
191_L	196_V	0.631	0.62
448_L	455_L	0.631	0.62
238_V	243_G	0.631	0.62
368_G	371_R	0.631	0.62
237_L	243_G	0.630	0.62
32_L	68_L	0.629	0.62
299_R	427_D	0.628	0.62
128_E	377_E	0.628	0.62
75_P	82_Q	0.628	0.62
449_C	454_A	0.628	0.62
95_L	167_L	0.624	0.61
257_T	262_K	0.624	0.61
130_M	135_F	0.622	0.61
192_R	198_L	0.622	0.61
148_V	175_S	0.622	0.61
102_A	127_T	0.621	0.61
384_R	422_Q	0.621	0.61
30_F	199_I	0.621	0.61
205_L	237_L	0.621	0.61
382_A	396_T	0.620	0.61
18_F	21_G	0.619	0.61
102_A	140_R	0.618	0.61
169_L	208_V	0.618	0.61
263_P	284_R	0.616	0.60
362_A	433_I	0.615	0.60
379_Q	383_E	0.614	0.60
295_L	299_R	0.614	0.60
291_L	480_Q	0.613	0.60
279_F	475_M	0.613	0.60
191_L	430_T	0.613	0.60
261_D	268_K	0.613	0.60
24_A	394_P	0.611	0.60
169_L	200_F	0.610	0.60
473_I	482_A	0.609	0.60
276_I	302_T	0.609	0.60
246_L	251_L	0.607	0.59
110_E	122_M	0.607	0.59
52_I	93_V	0.607	0.59
372_P	400_I	0.606	0.59
400_I	415_R	0.606	0.59
51_L	218_L	0.604	0.59
12_T	52_I	0.603	0.59
248_T	251_L	0.603	0.59
376_K	380_E	0.603	0.59
248_T	252_Q	0.601	0.59
459_S	464_E	0.601	0.59
345_K	408_Q	0.601	0.59
303_A	427_D	0.600	0.58
146_F	150_M	0.600	0.58
367_R	381_I	0.600	0.58
316_T	321_G	0.600	0.58
485_P	493_A	0.600	0.58
19_F	55_L	0.600	0.58
130_M	133_Y	0.600	0.58
32_L	38_M	0.599	0.58
200_F	208_V	0.599	0.58
93_V	148_V	0.598	0.58
208_V	461_E	0.598	0.58
282_E	483_E	0.597	0.58
368_G	372_P	0.596	0.58
430_T	433_I	0.596	0.58
446_E	450_A	0.595	0.58
217_V	419_T	0.594	0.58
410_K	430_T	0.594	0.58
56_T	82_Q	0.592	0.57
10_L	30_F	0.589	0.57
380_E	387_R	0.589	0.57
267_F	281_L	0.589	0.57
52_I	90_Y	0.589	0.57
475_M	482_A	0.589	0.57
25_L	130_M	0.588	0.57
446_E	449_C	0.586	0.57
83_Q	121_E	0.585	0.57
130_M	157_C	0.584	0.56
87_G	162_L	0.584	0.56
172_P	180_E	0.583	0.56
125_R	163_S	0.582	0.56
353_A	357_E	0.581	0.56
406_G	409_Q	0.580	0.56
359_I	381_I	0.577	0.55
25_L	28_V	0.577	0.55
12_T	28_V	0.576	0.55
438_H	442_I	0.576	0.55
93_V	345_K	0.574	0.55
413_L	417_L	0.573	0.55
72_A	124_K	0.572	0.55
449_C	457_V	0.571	0.55
312_A	325_N	0.569	0.54
462_L	469_A	0.569	0.54
349_I	353_A	0.568	0.54
472_V	486_L	0.568	0.54
252_Q	439_A	0.568	0.54
259_L	285_P	0.568	0.54
53_K	403_L	0.567	0.54
272_K	313_D	0.566	0.54
247_D	251_L	0.566	0.54
246_L	252_Q	0.566	0.54
105_L	129_L	0.566	0.54
388_Q	444_L	0.566	0.54
439_A	442_I	0.565	0.54
238_V	428_E	0.564	0.54
33_R	228_E	0.563	0.54
200_F	211_V	0.563	0.54
338_G	419_T	0.563	0.54
37_I	211_V	0.563	0.54
393_T	396_T	0.562	0.54
217_V	227_R	0.561	0.53
75_P	78_T	0.561	0.53
102_A	106_F	0.560	0.53
168_I	201_V	0.560	0.53
342_E	348_G	0.560	0.53
400_I	403_L	0.559	0.53
257_T	261_D	0.559	0.53
421_P	424_L	0.558	0.53
367_R	371_R	0.558	0.53
406_G	410_K	0.558	0.53
272_K	275_T	0.558	0.53
105_L	210_Q	0.557	0.53
130_M	139_V	0.557	0.53
138_D	142_P	0.557	0.53
127_T	136_S	0.557	0.53
42_G	45_G	0.556	0.53
89_V	151_Q	0.556	0.53
69_E	193_D	0.556	0.53
21_G	393_T	0.555	0.53
69_E	166_V	0.555	0.53
106_F	162_L	0.554	0.53
288_I	446_E	0.553	0.52
307_F	339_F	0.552	0.52
123_E	126_A	0.552	0.52
37_I	212_S	0.551	0.52
66_I	73_I	0.551	0.52
407_N	410_K	0.549	0.52
49_S	424_L	0.549	0.52
98_N	142_P	0.549	0.52
254_A	487_A	0.548	0.52
357_E	375_R	0.548	0.52
417_L	448_L	0.547	0.52
141_E	150_M	0.547	0.52
285_P	288_I	0.545	0.51
263_P	267_F	0.543	0.51
261_D	271_G	0.542	0.51
113_R	121_E	0.542	0.51
307_F	425_I	0.542	0.51
260_S	268_K	0.542	0.51
406_G	432_G	0.541	0.51
266_A	271_G	0.541	0.51
31_S	226_C	0.540	0.51
355_V	400_I	0.540	0.51
28_V	55_L	0.540	0.51
88_T	161_D	0.540	0.51
68_L	73_I	0.539	0.51
41_L	217_V	0.539	0.51
279_F	302_T	0.538	0.50
238_V	242_L	0.538	0.50
45_G	48_K	0.538	0.50
113_R	118_R	0.537	0.50
319_I	422_Q	0.536	0.50
186_D	210_Q	0.536	0.50
476_R	494_I	0.536	0.50
265_A	271_G	0.536	0.50
188_M	192_R	0.535	0.50
149_A	153_I	0.535	0.50
427_D	438_H	0.533	0.50
462_L	465_L	0.532	0.50
220_N	463_E	0.531	0.50
21_G	394_P	0.529	0.49
41_L	218_L	0.529	0.49
405_G	434_D	0.528	0.49
339_F	347_D	0.528	0.49
433_I	444_L	0.528	0.49
137_L	157_C	0.528	0.49
246_L	250_A	0.527	0.49
220_N	491_V	0.527	0.49
442_I	446_E	0.527	0.49
135_F	187_L	0.527	0.49
123_E	139_V	0.526	0.49
348_G	412_L	0.526	0.49
40_L	358_N	0.525	0.49
403_L	409_Q	0.525	0.49
42_G	48_K	0.525	0.49
61_A	65_T	0.525	0.49
405_G	432_G	0.525	0.49
405_G	410_K	0.524	0.49
43_E	155_A	0.524	0.49
382_A	391_I	0.524	0.49
389_L	414_S	0.524	0.49
36_E	382_A	0.523	0.49
120_K	123_E	0.523	0.49
277_A	477_D	0.522	0.48
244_R	250_A	0.521	0.48
36_E	70_G	0.521	0.48
151_Q	167_L	0.521	0.48
359_I	385_F	0.520	0.48
148_V	431_R	0.520	0.48
425_I	456_L	0.520	0.48
159_A	167_L	0.519	0.48
305_V	310_K	0.519	0.48
220_N	392_R	0.519	0.48
409_Q	434_D	0.519	0.48
103_D	341_P	0.518	0.48
27_N	291_L	0.517	0.48
149_A	162_L	0.516	0.48
291_L	302_T	0.516	0.48
225_G	236_E	0.516	0.48
436_G	461_E	0.515	0.47
177_D	201_V	0.515	0.47
218_L	240_M	0.515	0.47
53_K	94_N	0.514	0.47
332_A	337_I	0.514	0.47
55_L	168_I	0.514	0.47
297_S	428_E	0.514	0.47
359_I	414_S	0.513	0.47
480_Q	483_E	0.513	0.47
360_I	364_Q	0.512	0.47
215_I	232_L	0.512	0.47
188_M	291_L	0.511	0.47
422_Q	461_E	0.511	0.47
109_R	162_L	0.511	0.47
192_R	211_V	0.511	0.47
466_V	488_E	0.511	0.47
299_R	342_E	0.511	0.47
152_Q	204_F	0.510	0.47
88_T	204_F	0.510	0.47
404_S	409_Q	0.510	0.47
474_I	480_Q	0.509	0.47
233_P	237_L	0.509	0.47
456_L	469_A	0.508	0.47
106_F	126_A	0.508	0.47
54_A	59_Y	0.508	0.47
451_D	490_S	0.507	0.46
200_F	339_F	0.507	0.46
435_V	460_S	0.507	0.46
442_I	463_E	0.507	0.46
204_F	304_E	0.506	0.46
344_R	348_G	0.506	0.46
13_E	63_R	0.506	0.46
356_R	382_A	0.506	0.46
215_I	227_R	0.506	0.46
349_I	408_Q	0.506	0.46
52_I	177_D	0.505	0.46
291_L	454_A	0.504	0.46
241_M	244_R	0.504	0.46
19_F	180_E	0.504	0.46
112_K	138_D	0.504	0.46
136_S	150_M	0.504	0.46
40_L	52_I	0.503	0.46
414_S	417_L	0.503	0.46
148_V	177_D	0.502	0.46
259_L	270_Y	0.501	0.46
37_I	189_R	0.501	0.46
90_Y	94_N	0.501	0.46
389_L	417_L	0.500	0.46
18_F	26_D	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4q9hA	1	0.964	100	0.438	Contact Map
4finA	2	0.91	100	0.461	Contact Map
4f4cA	1	0.956	100	0.473	Contact Map
1yqtA	1	0.9	100	0.491	Contact Map
3ux8A	2	0.842	100	0.496	Contact Map
3bk7A	1	0.924	100	0.499	Contact Map
3ozxA	1	0.882	100	0.505	Contact Map
2iw3A	2	0.91	100	0.507	Contact Map
3j16B	1	0.914	100	0.518	Contact Map
2vf7A	2	0.964	100	0.587	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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