COPA - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

COPA - Copper-exporting P-type ATPase A

UniProt:	Q59385	Sequences: MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVTGTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQLLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYGAEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSLWLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQWFPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEKSVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGTVVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALVSAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDADALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLARAILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNEQQVGTKAIEAEITAQASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANAIAKEAGIDEVIAGVLPDGKAEAIKHLQSEGRQVAMVGDGINDAPALAQADVGIAMGGGSDVAIETAAITLMRHSLMGVADALAISRATLHNMKQNLLGAFIYNSIGIPVAAGILWPFTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13246
Length:	834 (710)
Sequences:	9816 (6485)
Seq/√Len:	243.4

ECOLI - COPA ATZN
BACSU - COPA CADA ZOSA
HALSA - Q9HRH2 Q9HN90 Q9HSN5
SULSO - Q97VH4 Q97UU7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
677_P	681_N	4.734	1.00
227_L	264_W	4.181	1.00
668_R	691_E	4.029	1.00
360_E	402_R	3.876	1.00
366_A	399_V	3.751	1.00
556_L	593_G	3.713	1.00
704_A	707_H	3.607	1.00
584_R	592_S	3.541	1.00
598_H	638_D	3.536	1.00
518_D	713_R	3.294	1.00
637_V	642_V	3.263	1.00
589_L	610_E	3.185	1.00
709_Q	730_Q	3.120	1.00
700_G	703_E	3.102	1.00
677_P	695_G	3.098	1.00
517_L	716_A	3.076	1.00
537_A	630_A	3.053	1.00
346_L	400_L	3.047	1.00
654_D	756_S	3.044	1.00
329_T	334_K	3.001	1.00
582_G	594_E	2.974	1.00
363_Q	400_L	2.936	1.00
324_T	335_S	2.881	1.00
673_T	680_A	2.878	1.00
346_L	362_T	2.855	1.00
326_R	335_S	2.795	1.00
106_S	160_G	2.780	1.00
555_A	578_P	2.614	1.00
549_A	643_A	2.530	1.00
327_L	334_K	2.529	1.00
663_H	690_D	2.528	1.00
366_A	394_V	2.523	1.00
546_E	575_M	2.506	1.00
684_A	692_V	2.454	1.00
706_K	730_Q	2.453	1.00
535_V	571_K	2.446	1.00
328_V	400_L	2.445	1.00
355_V	368_L	2.411	1.00
357_V	403_A	2.386	1.00
346_L	402_R	2.386	1.00
388_V	401_F	2.382	1.00
681_N	685_K	2.373	1.00
571_K	575_M	2.345	1.00
716_A	735_I	2.330	1.00
592_S	599_A	2.322	1.00
668_R	713_R	2.310	1.00
693_I	704_A	2.308	1.00
598_H	637_V	2.300	1.00
326_R	353_D	2.300	1.00
196_G	294_G	2.291	1.00
271_N	286_Y	2.290	1.00
601_L	611_Q	2.289	1.00
656_V	660_Q	2.271	1.00
586_L	607_L	2.223	1.00
535_V	645_L	2.199	1.00
329_T	332_G	2.198	1.00
621_E	624_A	2.189	1.00
530_E	650_P	2.183	1.00
665_A	765_A	2.173	1.00
530_E	653_S	2.121	1.00
498_A	766_I	2.108	1.00
600_L	637_V	2.087	1.00
707_H	711_E	2.087	1.00
362_T	402_R	2.066	1.00
341_V	357_V	2.027	1.00
361_I	399_V	2.025	1.00
552_L	600_L	2.025	1.00
602_L	635_L	2.025	1.00
528_L	687_A	2.024	1.00
608_L	636_A	2.023	1.00
146_S	149_D	1.948	1.00
383_G	386_D	1.947	1.00
521_V	705_I	1.940	1.00
622_I	634_L	1.937	1.00
261_G	265_L	1.930	1.00
100_S	142_M	1.925	1.00
452_A	471_A	1.924	1.00
235_G	239_R	1.895	1.00
239_R	243_K	1.886	1.00
451_S	470_I	1.884	1.00
779_L	783_I	1.859	1.00
663_H	669_L	1.842	1.00
114_V	134_L	1.827	1.00
152_Q	156_K	1.822	1.00
155_E	160_G	1.813	1.00
657_A	758_M	1.813	1.00
545_D	548_Q	1.812	1.00
518_D	714_Q	1.810	1.00
773_N	826_R	1.807	1.00
192_A	233_A	1.801	1.00
658_A	761_A	1.800	1.00
632_P	644_L	1.798	1.00
660_Q	664_K	1.790	1.00
238_Y	261_G	1.785	1.00
709_Q	732_D	1.779	1.00
703_E	706_K	1.771	1.00
681_N	692_V	1.769	1.00
519_T	670_V	1.747	1.00
341_V	347_L	1.746	1.00
417_R	421_Q	1.731	1.00
633_V	647_V	1.730	1.00
327_L	336_V	1.727	1.00
672_L	704_A	1.726	1.00
328_V	333_E	1.717	1.00
594_E	599_A	1.713	1.00
651_L	687_A	1.710	1.00
446_V	450_V	1.710	1.00
670_V	691_E	1.704	1.00
553_A	635_L	1.703	1.00
739_G	755_H	1.702	1.00
129_Q	142_M	1.702	1.00
634_L	641_A	1.692	1.00
435_K	439_V	1.691	1.00
521_V	708_L	1.690	1.00
333_E	348_R	1.688	1.00
554_A	572_A	1.676	1.00
151_V	161_A	1.662	1.00
521_V	672_L	1.648	1.00
193_L	294_G	1.645	1.00
536_V	630_A	1.643	1.00
661_R	765_A	1.643	1.00
223_G	268_M	1.638	1.00
188_Q	236_H	1.629	1.00
571_K	574_D	1.628	1.00
519_T	713_R	1.617	1.00
359_G	401_F	1.616	1.00
373_L	389_H	1.615	1.00
702_A	730_Q	1.610	1.00
635_L	643_A	1.610	1.00
624_A	628_Q	1.605	1.00
329_T	345_M	1.598	1.00
348_R	400_L	1.592	1.00
566_R	570_D	1.585	1.00
706_K	710_S	1.580	1.00
110_C	113_C	1.577	1.00
671_M	680_A	1.577	1.00
360_E	404_S	1.576	1.00
530_E	534_Q	1.569	1.00
656_V	686_E	1.565	1.00
592_S	601_L	1.557	1.00
794_G	802_T	1.553	1.00
693_I	707_H	1.551	1.00
659_L	669_L	1.550	1.00
327_L	345_M	1.550	1.00
608_L	613_V	1.542	1.00
360_E	385_G	1.541	1.00
454_I	458_F	1.539	1.00
403_A	406_V	1.537	1.00
604_N	607_L	1.529	1.00
544_V	642_V	1.513	1.00
230_M	238_Y	1.512	1.00
497_R	501_F	1.511	1.00
657_A	661_R	1.511	1.00
494_G	770_T	1.511	1.00
548_Q	551_R	1.506	1.00
551_R	596_E	1.505	1.00
257_A	261_G	1.504	1.00
361_I	368_L	1.499	1.00
501_F	762_D	1.499	1.00
258_L	445_V	1.493	1.00
586_L	592_S	1.493	1.00
344_G	402_R	1.491	1.00
561_S	585_T	1.487	1.00
365_E	381_Q	1.484	1.00
520_V	716_A	1.484	1.00
200_M	291_M	1.483	1.00
706_K	709_Q	1.473	1.00
365_E	383_G	1.459	1.00
347_L	401_F	1.457	1.00
326_R	333_E	1.454	1.00
605_Q	609_N	1.445	1.00
387_S	404_S	1.443	1.00
568_I	645_L	1.430	1.00
369_D	395_Q	1.430	1.00
516_T	714_Q	1.426	1.00
447_I	793_A	1.412	1.00
556_L	591_V	1.409	1.00
654_D	758_M	1.408	1.00
773_N	824_A	1.406	1.00
459_G	463_Q	1.405	1.00
551_R	578_P	1.404	1.00
101_Q	143_G	1.403	1.00
668_R	690_D	1.400	1.00
349_L	401_F	1.399	1.00
452_A	456_Y	1.396	1.00
625_Q	646_A	1.393	1.00
149_D	152_Q	1.389	1.00
522_F	528_L	1.387	1.00
367_W	381_Q	1.382	1.00
583_F	591_V	1.379	1.00
557_E	565_A	1.371	1.00
627_S	678_T	1.371	1.00
601_L	636_A	1.367	1.00
754_R	759_G	1.362	1.00
189_A	298_L	1.359	1.00
601_L	607_L	1.357	1.00
121_L	139_A	1.357	1.00
490_S	824_A	1.351	1.00
387_S	405_A	1.350	1.00
528_L	651_L	1.349	1.00
605_Q	634_L	1.347	1.00
456_Y	464_I	1.346	1.00
460_P	463_Q	1.343	1.00
600_L	642_V	1.342	1.00
368_L	399_V	1.340	1.00
536_V	648_R	1.339	1.00
370_E	382_K	1.335	1.00
578_P	596_E	1.322	1.00
238_Y	257_A	1.318	1.00
497_R	500_E	1.316	1.00
398_S	559_G	1.316	1.00
122_Q	129_Q	1.314	1.00
673_T	694_A	1.313	1.00
555_A	577_L	1.311	1.00
534_Q	570_D	1.309	1.00
544_V	549_A	1.304	1.00
547_A	575_M	1.303	1.00
128_T	142_M	1.302	1.00
556_L	600_L	1.298	1.00
229_V	290_A	1.297	1.00
348_R	398_S	1.296	1.00
118_Q	122_Q	1.294	1.00
735_I	760_V	1.284	1.00
534_Q	650_P	1.279	1.00
703_E	707_H	1.278	1.00
691_E	711_E	1.277	1.00
581_N	594_E	1.275	1.00
580_V	593_G	1.264	1.00
153_A	157_A	1.257	1.00
121_L	130_A	1.252	1.00
665_A	768_R	1.251	1.00
124_V	153_A	1.251	1.00
514_A	733_V	1.250	1.00
541_F	618_I	1.244	1.00
325_A	356_P	1.242	1.00
540_T	643_A	1.241	1.00
361_I	364_G	1.231	1.00
407_G	410_T	1.229	1.00
328_V	348_R	1.228	1.00
450_V	454_I	1.226	1.00
122_Q	130_A	1.219	1.00
522_F	669_L	1.216	1.00
360_E	387_S	1.215	1.00
102_Q	138_T	1.210	1.00
542_A	640_K	1.208	1.00
152_Q	155_E	1.206	1.00
132_V	139_A	1.202	1.00
595_A	600_L	1.200	1.00
539_K	621_E	1.194	1.00
100_S	140_L	1.192	1.00
630_A	646_A	1.192	1.00
776_Q	823_N	1.191	1.00
151_V	155_E	1.191	1.00
347_L	403_A	1.190	1.00
586_L	589_L	1.186	1.00
531_G	649_D	1.186	1.00
589_L	697_L	1.186	1.00
337_P	340_E	1.185	1.00
106_S	162_E	1.183	1.00
533_P	564_L	1.174	1.00
555_A	580_V	1.172	1.00
535_V	647_V	1.171	1.00
600_L	635_L	1.164	1.00
127_V	150_L	1.163	1.00
540_T	549_A	1.162	1.00
613_V	641_A	1.162	1.00
326_R	350_T	1.158	1.00
580_V	595_A	1.158	1.00
194_A	198_P	1.157	1.00
618_I	641_A	1.156	1.00
613_V	636_A	1.154	1.00
680_A	692_V	1.153	1.00
538_V	571_K	1.152	1.00
696_V	700_G	1.151	1.00
189_A	193_L	1.149	1.00
505_V	750_I	1.148	1.00
121_L	150_L	1.147	1.00
558_Q	573_G	1.143	1.00
699_D	703_E	1.142	1.00
242_W	246_L	1.141	1.00
230_M	289_S	1.140	1.00
124_V	145_A	1.138	1.00
388_V	399_V	1.137	1.00
490_S	773_N	1.137	1.00
654_D	658_A	1.134	1.00
539_K	625_Q	1.133	1.00
619_E	623_T	1.132	1.00
592_S	611_Q	1.130	1.00
230_M	261_G	1.125	1.00
729_A	747_T	1.122	1.00
104_L	164_I	1.117	1.00
363_Q	384_E	1.114	1.00
439_V	443_V	1.113	1.00
515_S	771_L	1.110	1.00
794_G	803_L	1.109	1.00
551_R	555_A	1.109	1.00
316_K	500_E	1.102	1.00
553_A	645_L	1.100	1.00
570_D	573_G	1.100	1.00
184_R	188_Q	1.098	1.00
328_V	346_L	1.097	1.00
661_R	665_A	1.096	1.00
771_L	775_K	1.094	1.00
128_T	144_S	1.094	1.00
623_T	627_S	1.092	1.00
549_A	635_L	1.088	1.00
234_G	293_I	1.087	1.00
327_L	347_L	1.087	1.00
102_Q	140_L	1.085	1.00
651_L	683_I	1.084	1.00
513_R	714_Q	1.083	1.00
672_L	696_V	1.082	1.00
589_L	606_A	1.074	1.00
661_R	664_K	1.072	1.00
553_A	602_L	1.071	1.00
601_L	613_V	1.070	1.00
183_K	187_W	1.067	1.00
105_L	108_M	1.061	1.00
554_A	577_L	1.059	1.00
445_V	449_L	1.059	1.00
361_I	386_D	1.058	1.00
581_N	597_G	1.057	1.00
456_Y	467_T	1.057	1.00
336_V	340_E	1.057	1.00
190_I	194_A	1.049	1.00
305_R	309_R	1.047	1.00
580_V	583_F	1.046	1.00
707_H	710_S	1.043	1.00
514_A	764_L	1.043	1.00
769_A	772_H	1.042	1.00
677_P	694_A	1.042	1.00
603_G	607_L	1.041	1.00
138_T	420_R	1.040	1.00
514_A	763_A	1.037	1.00
657_A	660_Q	1.034	1.00
513_R	516_T	1.033	1.00
105_L	139_A	1.032	1.00
556_L	602_L	1.032	1.00
676_N	679_T	1.028	1.00
115_T	119_N	1.027	1.00
372_M	392_T	1.026	1.00
223_G	264_W	1.024	1.00
351_T	366_A	1.021	1.00
810_G	814_A	1.017	1.00
103_L	151_V	1.016	1.00
538_V	645_L	1.014	1.00
196_G	229_V	1.014	1.00
453_A	457_F	1.014	1.00
661_R	758_M	1.013	1.00
347_L	357_V	1.013	1.00
120_A	157_A	1.012	1.00
665_A	764_L	1.012	1.00
264_W	268_M	1.009	1.00
351_T	585_T	1.006	1.00
187_W	191_V	1.005	1.00
316_K	743_V	1.000	1.00
709_Q	715_V	1.000	1.00
414_R	417_R	0.999	1.00
667_Y	764_L	0.997	1.00
343_P	406_V	0.996	1.00
528_L	671_M	0.994	1.00
564_L	647_V	0.993	1.00
601_L	608_L	0.992	1.00
823_N	826_R	0.992	1.00
351_T	394_V	0.990	1.00
532_K	570_D	0.989	1.00
219_W	284_L	0.988	1.00
121_L	124_V	0.986	1.00
625_Q	630_A	0.985	1.00
520_V	718_V	0.983	1.00
541_F	641_A	0.982	1.00
114_V	117_V	0.981	1.00
189_A	301_M	0.980	1.00
250_A	254_T	0.979	1.00
520_V	667_Y	0.973	1.00
714_Q	732_D	0.973	1.00
230_M	260_T	0.972	1.00
670_V	704_A	0.971	1.00
537_A	646_A	0.971	1.00
338_L	341_V	0.970	1.00
548_Q	598_H	0.967	1.00
199_V	290_A	0.962	1.00
554_A	569_L	0.960	1.00
103_L	161_A	0.960	1.00
350_T	353_D	0.960	1.00
660_Q	663_H	0.958	1.00
637_V	640_K	0.957	1.00
540_T	543_D	0.956	1.00
101_Q	147_P	0.954	1.00
228_A	232_F	0.952	1.00
199_V	226_T	0.951	1.00
570_D	574_D	0.948	1.00
693_I	696_V	0.947	1.00
335_S	353_D	0.946	1.00
606_A	695_G	0.943	1.00
620_A	623_T	0.942	1.00
605_Q	619_E	0.940	1.00
186_R	190_I	0.939	1.00
773_N	776_Q	0.939	1.00
550_L	571_K	0.938	1.00
818_I	822_S	0.938	1.00
464_I	468_L	0.936	1.00
145_A	149_D	0.935	1.00
671_M	689_I	0.933	1.00
466_Y	470_I	0.932	1.00
470_I	473_T	0.932	1.00
659_L	663_H	0.931	1.00
513_R	732_D	0.930	1.00
359_G	388_V	0.930	1.00
661_R	761_A	0.930	1.00
244_S	251_T	0.930	1.00
519_T	668_R	0.928	1.00
528_L	659_L	0.927	1.00
118_Q	426_K	0.925	1.00
117_V	157_A	0.924	1.00
507_D	749_A	0.923	1.00
517_L	714_Q	0.923	1.00
676_N	695_G	0.921	1.00
260_T	293_I	0.920	1.00
677_P	692_V	0.920	1.00
218_L	222_I	0.920	1.00
219_W	271_N	0.919	1.00
764_L	768_R	0.918	1.00
477_I	788_G	0.918	1.00
355_V	388_V	0.917	1.00
759_G	762_D	0.916	1.00
351_T	561_S	0.915	1.00
788_G	808_V	0.914	1.00
365_E	582_G	0.912	1.00
665_A	761_A	0.909	1.00
292_I	810_G	0.907	1.00
414_R	699_D	0.907	1.00
536_V	646_A	0.907	1.00
204_M	207_D	0.907	1.00
463_Q	466_Y	0.905	1.00
310_S	496_G	0.904	1.00
702_A	706_K	0.901	1.00
639_G	642_V	0.899	1.00
621_E	625_Q	0.898	1.00
368_L	388_V	0.898	1.00
356_P	401_F	0.897	1.00
405_A	409_H	0.894	1.00
651_L	656_V	0.893	1.00
183_K	186_R	0.890	1.00
238_Y	260_T	0.888	1.00
444_V	789_I	0.887	1.00
244_S	254_T	0.886	1.00
342_Q	345_M	0.885	1.00
684_A	689_I	0.885	1.00
349_L	355_V	0.884	1.00
718_V	760_V	0.884	1.00
522_F	760_V	0.882	1.00
203_G	222_I	0.882	1.00
736_A	740_G	0.882	1.00
672_L	693_I	0.881	0.99
451_S	474_V	0.879	0.99
154_V	161_A	0.876	0.99
695_G	700_G	0.876	0.99
124_V	150_L	0.875	0.99
191_V	233_A	0.872	0.99
534_Q	574_D	0.872	0.99
556_L	635_L	0.871	0.99
329_T	336_V	0.865	0.99
655_S	659_L	0.864	0.99
148_Q	152_Q	0.863	0.99
203_G	206_G	0.863	0.99
622_I	626_A	0.863	0.99
540_T	546_E	0.862	0.99
241_A	250_A	0.862	0.99
624_A	627_S	0.861	0.99
552_L	637_V	0.856	0.99
367_W	396_D	0.856	0.99
515_S	767_S	0.855	0.99
347_L	356_P	0.854	0.99
226_T	290_A	0.854	0.99
609_N	619_E	0.853	0.99
182_M	186_R	0.853	0.99
365_E	384_E	0.852	0.99
105_L	161_A	0.852	0.99
673_T	692_V	0.852	0.99
750_I	763_A	0.851	0.99
390_A	410_T	0.851	0.99
151_V	163_A	0.850	0.99
608_L	611_Q	0.850	0.99
209_M	213_A	0.850	0.99
561_S	583_F	0.849	0.99
355_V	399_V	0.849	0.99
233_A	297_N	0.848	0.99
395_Q	566_R	0.845	0.99
361_I	366_A	0.844	0.99
104_L	162_E	0.844	0.99
538_V	550_L	0.843	0.99
522_F	662_L	0.843	0.99
349_L	356_P	0.843	0.99
188_Q	235_G	0.842	0.99
312_K	315_E	0.841	0.99
341_V	403_A	0.841	0.99
537_A	546_E	0.839	0.99
151_V	160_G	0.835	0.99
120_A	124_V	0.834	0.99
601_L	639_G	0.833	0.99
622_I	632_P	0.831	0.99
514_A	750_I	0.830	0.99
521_V	696_V	0.830	0.99
769_A	773_N	0.829	0.99
555_A	579_Q	0.827	0.99
405_A	414_R	0.826	0.99
815_L	819_T	0.826	0.99
220_L	272_L	0.826	0.99
199_V	203_G	0.825	0.99
736_A	748_A	0.825	0.99
594_E	597_G	0.822	0.99
541_F	544_V	0.816	0.99
628_Q	686_E	0.815	0.99
210_M	213_A	0.813	0.99
548_Q	552_L	0.813	0.99
467_T	471_A	0.812	0.99
537_A	625_Q	0.812	0.99
406_V	410_T	0.812	0.99
234_G	260_T	0.812	0.99
661_R	762_D	0.811	0.99
553_A	568_I	0.811	0.99
188_Q	192_A	0.811	0.99
783_I	787_I	0.811	0.99
347_L	359_G	0.810	0.99
130_A	139_A	0.810	0.99
309_R	312_K	0.810	0.99
138_T	164_I	0.809	0.99
452_A	467_T	0.807	0.99
620_A	624_A	0.805	0.99
509_D	513_R	0.805	0.99
220_L	224_L	0.805	0.99
186_R	301_M	0.805	0.99
536_V	625_Q	0.803	0.99
355_V	401_F	0.802	0.99
139_A	154_V	0.801	0.99
120_A	153_A	0.801	0.99
520_V	669_L	0.799	0.99
605_Q	626_A	0.799	0.99
389_H	392_T	0.799	0.99
595_A	598_H	0.799	0.99
269_S	273_W	0.798	0.99
654_D	657_A	0.798	0.99
540_T	544_V	0.794	0.99
327_L	341_V	0.792	0.99
411_T	699_D	0.791	0.99
377_P	679_T	0.790	0.99
705_I	717_M	0.788	0.99
652_R	755_H	0.787	0.99
436_I	782_F	0.786	0.99
772_H	776_Q	0.785	0.99
108_M	113_C	0.784	0.99
291_M	807_V	0.784	0.99
147_P	163_A	0.783	0.99
312_K	316_K	0.782	0.99
243_K	246_L	0.781	0.99
728_L	744_A	0.781	0.99
518_D	712_G	0.780	0.99
318_L	745_I	0.779	0.99
182_M	301_M	0.779	0.99
551_R	576_Q	0.778	0.99
382_K	386_D	0.778	0.99
108_M	117_V	0.777	0.99
353_D	561_S	0.777	0.99
245_L	254_T	0.777	0.99
223_G	227_L	0.776	0.99
683_I	686_E	0.775	0.99
549_A	553_A	0.775	0.99
616_K	619_E	0.774	0.99
241_A	254_T	0.773	0.99
606_A	609_N	0.771	0.99
196_G	199_V	0.771	0.99
788_G	791_V	0.771	0.99
223_G	286_Y	0.770	0.99
406_V	409_H	0.770	0.99
558_Q	577_L	0.769	0.99
537_A	628_Q	0.767	0.99
454_I	457_F	0.766	0.99
607_L	611_Q	0.766	0.99
396_D	587_R	0.765	0.99
679_T	682_A	0.764	0.99
608_L	634_L	0.763	0.99
505_V	511_L	0.763	0.99
192_A	297_N	0.763	0.99
782_F	786_S	0.763	0.99
528_L	655_S	0.762	0.99
623_T	626_A	0.762	0.99
658_A	758_M	0.761	0.99
193_L	298_L	0.758	0.98
325_A	341_V	0.757	0.98
539_K	644_L	0.756	0.98
448_A	471_A	0.756	0.98
431_Q	435_K	0.756	0.98
822_S	826_R	0.756	0.98
626_A	632_P	0.754	0.98
195_V	229_V	0.753	0.98
648_R	686_E	0.752	0.98
507_D	510_A	0.750	0.98
446_V	449_L	0.750	0.98
599_A	639_G	0.749	0.98
390_A	411_T	0.748	0.98
319_D	323_P	0.748	0.98
117_V	154_V	0.746	0.98
555_A	595_A	0.746	0.98
700_G	704_A	0.746	0.98
669_L	689_I	0.745	0.98
288_A	292_I	0.744	0.98
453_A	456_Y	0.742	0.98
655_S	658_A	0.741	0.98
298_L	302_L	0.741	0.98
154_V	160_G	0.740	0.98
106_S	137_R	0.740	0.98
654_D	757_L	0.739	0.98
241_A	246_L	0.739	0.98
361_I	388_V	0.738	0.98
608_L	612_Q	0.738	0.98
370_E	392_T	0.738	0.98
519_T	708_L	0.737	0.98
494_G	766_I	0.734	0.98
517_L	764_L	0.734	0.98
147_P	151_V	0.733	0.98
411_T	415_I	0.732	0.98
557_E	602_L	0.731	0.98
791_V	808_V	0.730	0.98
334_K	340_E	0.729	0.98
143_G	150_L	0.729	0.98
487_T	774_M	0.728	0.98
659_L	687_A	0.728	0.98
108_M	132_V	0.727	0.98
490_S	770_T	0.727	0.98
396_D	584_R	0.726	0.98
741_S	745_I	0.726	0.98
500_E	828_L	0.725	0.98
579_Q	596_E	0.725	0.98
697_L	700_G	0.725	0.98
362_T	384_E	0.725	0.98
185_F	297_N	0.723	0.98
451_S	471_A	0.723	0.98
634_L	644_L	0.723	0.98
373_L	411_T	0.722	0.98
658_A	757_L	0.721	0.98
811_A	814_A	0.719	0.98
192_A	294_G	0.719	0.98
349_L	388_V	0.718	0.98
628_Q	685_K	0.713	0.98
493_S	828_L	0.713	0.98
626_A	678_T	0.712	0.98
212_T	215_N	0.712	0.98
452_A	464_I	0.712	0.98
343_P	409_H	0.711	0.98
224_L	228_A	0.710	0.98
268_M	271_N	0.709	0.98
189_A	192_A	0.709	0.98
405_A	411_T	0.708	0.98
599_A	611_Q	0.707	0.98
112_S	115_T	0.706	0.98
776_Q	826_R	0.706	0.98
517_L	520_V	0.706	0.98
670_V	708_L	0.706	0.98
767_S	771_L	0.706	0.98
448_A	452_A	0.705	0.98
325_A	347_L	0.705	0.98
223_G	271_N	0.705	0.98
324_T	337_P	0.705	0.98
635_L	645_L	0.705	0.98
614_G	617_A	0.702	0.98
254_T	445_V	0.702	0.98
737_M	740_G	0.702	0.98
153_A	156_K	0.701	0.97
670_V	693_I	0.701	0.97
119_N	122_Q	0.701	0.97
118_Q	131_R	0.700	0.97
308_Q	311_S	0.699	0.97
226_T	229_V	0.699	0.97
141_V	150_L	0.699	0.97
359_G	404_S	0.699	0.97
514_A	517_L	0.699	0.97
517_L	667_Y	0.697	0.97
448_A	475_L	0.697	0.97
103_L	147_P	0.696	0.97
431_Q	512_Q	0.695	0.97
367_W	395_Q	0.693	0.97
316_K	319_D	0.693	0.97
455_W	467_T	0.689	0.97
683_I	687_A	0.688	0.97
616_K	620_A	0.686	0.97
773_N	823_N	0.685	0.97
522_F	655_S	0.684	0.97
489_M	821_V	0.682	0.97
333_E	558_Q	0.682	0.97
396_D	585_T	0.682	0.97
456_Y	459_G	0.680	0.97
368_L	382_K	0.679	0.97
577_L	580_V	0.678	0.97
363_Q	579_Q	0.677	0.97
535_V	538_V	0.676	0.97
196_G	200_M	0.675	0.97
196_G	291_M	0.673	0.97
199_V	202_W	0.672	0.97
323_P	354_R	0.672	0.97
143_G	147_P	0.672	0.97
334_K	345_M	0.672	0.97
219_W	222_I	0.670	0.97
205_I	208_N	0.670	0.97
240_S	253_D	0.669	0.97
544_V	548_Q	0.668	0.97
195_V	228_A	0.668	0.97
520_V	764_L	0.668	0.97
512_Q	516_T	0.666	0.97
201_V	205_I	0.664	0.97
251_T	254_T	0.664	0.97
357_V	390_A	0.663	0.96
550_L	572_A	0.663	0.96
672_L	705_I	0.662	0.96
682_A	686_E	0.662	0.96
755_H	759_G	0.660	0.96
696_V	702_A	0.660	0.96
228_A	231_V	0.660	0.96
741_S	744_A	0.659	0.96
126_G	144_S	0.656	0.96
552_L	642_V	0.655	0.96
589_L	607_L	0.655	0.96
145_A	150_L	0.654	0.96
349_L	359_G	0.654	0.96
668_R	711_E	0.653	0.96
195_V	199_V	0.653	0.96
326_R	348_R	0.651	0.96
318_L	416_I	0.650	0.96
581_N	596_E	0.648	0.96
345_M	357_V	0.648	0.96
213_A	216_R	0.646	0.96
605_Q	622_I	0.646	0.96
568_I	633_V	0.645	0.96
184_R	187_W	0.644	0.96
217_S	220_L	0.644	0.96
117_V	120_A	0.643	0.96
301_M	305_R	0.642	0.96
360_E	384_E	0.642	0.96
370_E	380_Q	0.640	0.96
310_S	489_M	0.640	0.96
556_L	580_V	0.639	0.96
737_M	745_I	0.639	0.96
187_W	190_I	0.638	0.96
237_F	293_I	0.637	0.96
772_H	775_K	0.637	0.96
196_G	290_A	0.636	0.96
432_L	436_I	0.636	0.96
231_V	235_G	0.635	0.96
262_V	472_T	0.634	0.95
541_F	644_L	0.634	0.95
780_G	819_T	0.633	0.95
758_M	761_A	0.632	0.95
364_G	397_G	0.632	0.95
761_A	765_A	0.631	0.95
354_R	393_V	0.631	0.95
190_I	193_L	0.631	0.95
522_F	718_V	0.630	0.95
621_E	644_L	0.629	0.95
538_V	553_A	0.629	0.95
549_A	645_L	0.629	0.95
206_G	209_M	0.629	0.95
601_L	637_V	0.629	0.95
745_I	751_T	0.629	0.95
571_K	645_L	0.629	0.95
116_R	249_A	0.628	0.95
178_A	181_T	0.628	0.95
300_H	307_R	0.625	0.95
505_V	763_A	0.625	0.95
503_V	762_D	0.625	0.95
203_G	207_D	0.624	0.95
663_H	668_R	0.624	0.95
346_L	363_Q	0.624	0.95
368_L	392_T	0.623	0.95
784_Y	819_T	0.623	0.95
329_T	342_Q	0.622	0.95
662_L	667_Y	0.621	0.95
813_M	816_S	0.620	0.95
653_S	686_E	0.620	0.95
559_G	580_V	0.620	0.95
222_I	226_T	0.620	0.95
417_R	420_R	0.618	0.95
378_I	381_Q	0.616	0.95
607_L	633_V	0.615	0.95
108_M	114_V	0.615	0.95
566_R	569_L	0.614	0.95
103_L	154_V	0.614	0.95
552_L	595_A	0.613	0.95
540_T	553_A	0.612	0.95
558_Q	579_Q	0.612	0.95
270_V	283_H	0.612	0.95
815_L	822_S	0.612	0.95
538_V	643_A	0.612	0.95
652_R	739_G	0.611	0.94
122_Q	125_P	0.611	0.94
491_I	774_M	0.611	0.94
604_N	634_L	0.611	0.94
785_N	813_M	0.609	0.94
425_S	509_D	0.609	0.94
548_Q	596_E	0.608	0.94
432_L	782_F	0.608	0.94
811_A	815_L	0.608	0.94
260_T	810_G	0.607	0.94
630_A	648_R	0.607	0.94
268_M	272_L	0.607	0.94
114_V	132_V	0.607	0.94
205_I	209_M	0.607	0.94
266_Y	270_V	0.607	0.94
185_F	188_Q	0.606	0.94
451_S	793_A	0.606	0.94
518_D	521_V	0.605	0.94
522_F	658_A	0.604	0.94
328_V	331_E	0.604	0.94
440_F	444_V	0.603	0.94
534_Q	571_K	0.603	0.94
341_V	345_M	0.603	0.94
761_A	764_L	0.602	0.94
105_L	117_V	0.600	0.94
473_T	809_A	0.600	0.94
559_G	569_L	0.599	0.94
209_M	215_N	0.597	0.94
783_I	786_S	0.596	0.94
245_L	248_G	0.596	0.94
515_S	768_R	0.595	0.94
582_G	592_S	0.594	0.94
572_A	577_L	0.594	0.94
551_R	577_L	0.594	0.94
623_T	678_T	0.593	0.94
333_E	400_L	0.593	0.94
333_E	350_T	0.592	0.94
433_A	438_A	0.592	0.94
549_A	642_V	0.592	0.94
599_A	638_D	0.589	0.93
559_G	583_F	0.589	0.93
638_D	642_V	0.589	0.93
705_I	715_V	0.588	0.93
521_V	670_V	0.588	0.93
361_I	383_G	0.588	0.93
357_V	407_G	0.587	0.93
220_L	228_A	0.586	0.93
111_A	114_V	0.586	0.93
662_L	760_V	0.586	0.93
680_A	694_A	0.585	0.93
625_Q	644_L	0.584	0.93
538_V	546_E	0.584	0.93
425_S	706_K	0.583	0.93
425_S	507_D	0.583	0.93
209_M	212_T	0.583	0.93
805_N	808_V	0.582	0.93
514_A	716_A	0.581	0.93
117_V	153_A	0.581	0.93
544_V	637_V	0.580	0.93
262_V	468_L	0.580	0.93
120_A	154_V	0.579	0.93
259_G	262_V	0.578	0.93
104_L	161_A	0.578	0.93
127_V	130_A	0.577	0.93
470_I	803_L	0.576	0.93
103_L	139_A	0.576	0.93
568_I	647_V	0.576	0.93
443_V	447_I	0.575	0.93
113_C	159_Y	0.574	0.92
408_S	413_S	0.574	0.92
291_M	295_L	0.573	0.92
553_A	571_K	0.572	0.92
256_V	810_G	0.572	0.92
716_A	733_V	0.571	0.92
515_S	775_K	0.571	0.92
264_W	289_S	0.570	0.92
354_R	369_D	0.569	0.92
532_K	566_R	0.568	0.92
366_A	396_D	0.568	0.92
367_W	378_I	0.568	0.92
124_V	127_V	0.567	0.92
607_L	613_V	0.567	0.92
429_I	771_L	0.566	0.92
589_L	604_N	0.566	0.92
513_R	733_V	0.566	0.92
108_M	134_L	0.565	0.92
223_G	272_L	0.565	0.92
604_N	608_L	0.565	0.92
369_D	532_K	0.564	0.92
606_A	697_L	0.564	0.92
791_V	802_T	0.564	0.92
109_S	113_C	0.563	0.92
108_M	137_R	0.563	0.92
271_N	284_L	0.563	0.92
438_A	442_P	0.563	0.92
607_L	636_A	0.563	0.92
121_L	127_V	0.562	0.92
226_T	230_M	0.560	0.92
265_L	268_M	0.560	0.92
143_G	146_S	0.559	0.91
323_P	338_L	0.558	0.91
338_L	357_V	0.557	0.91
267_S	286_Y	0.557	0.91
327_L	342_Q	0.557	0.91
231_V	264_W	0.557	0.91
126_G	145_A	0.556	0.91
469_V	473_T	0.556	0.91
344_G	360_E	0.556	0.91
137_R	307_R	0.556	0.91
687_A	757_L	0.556	0.91
115_T	134_L	0.556	0.91
460_P	466_Y	0.555	0.91
192_A	196_G	0.554	0.91
361_I	382_K	0.554	0.91
550_L	553_A	0.553	0.91
196_G	203_G	0.553	0.91
658_A	756_S	0.552	0.91
103_L	141_V	0.552	0.91
268_M	286_Y	0.552	0.91
131_R	140_L	0.552	0.91
770_T	823_N	0.551	0.91
328_V	398_S	0.551	0.91
585_T	722_I	0.551	0.91
155_E	161_A	0.550	0.91
233_A	293_I	0.550	0.91
230_M	264_W	0.550	0.91
403_A	407_G	0.550	0.91
118_Q	130_A	0.549	0.91
102_Q	164_I	0.548	0.91
226_T	264_W	0.548	0.91
442_P	812_A	0.548	0.91
158_G	163_A	0.548	0.91
518_D	715_V	0.548	0.91
573_G	577_L	0.547	0.91
336_V	345_M	0.547	0.91
385_G	402_R	0.547	0.91
519_T	715_V	0.547	0.91
454_I	794_G	0.546	0.91
433_A	778_L	0.546	0.91
112_S	116_R	0.544	0.90
230_M	265_L	0.544	0.90
136_E	420_R	0.542	0.90
752_L	760_V	0.542	0.90
219_W	223_G	0.542	0.90
315_E	319_D	0.542	0.90
148_Q	151_V	0.541	0.90
421_Q	424_S	0.541	0.90
648_R	682_A	0.540	0.90
119_N	123_S	0.540	0.90
243_K	247_N	0.539	0.90
236_H	297_N	0.539	0.90
415_I	722_I	0.539	0.90
292_I	296_I	0.538	0.90
293_I	297_N	0.538	0.90
494_G	511_L	0.538	0.90
788_G	804_L	0.538	0.90
469_V	472_T	0.538	0.90
814_A	818_I	0.538	0.90
655_S	757_L	0.538	0.90
601_L	638_D	0.537	0.90
323_P	339_A	0.536	0.90
188_Q	191_V	0.536	0.90
223_G	226_T	0.535	0.90
520_V	662_L	0.534	0.90
110_C	134_L	0.534	0.90
607_L	634_L	0.534	0.90
178_A	182_M	0.533	0.89
612_Q	615_T	0.533	0.89
222_I	284_L	0.532	0.89
117_V	134_L	0.532	0.89
641_A	644_L	0.532	0.89
117_V	121_L	0.532	0.89
327_L	333_E	0.532	0.89
625_Q	628_Q	0.532	0.89
242_W	254_T	0.532	0.89
682_A	685_K	0.531	0.89
519_T	712_G	0.531	0.89
702_A	705_I	0.529	0.89
489_M	493_S	0.529	0.89
459_G	466_Y	0.529	0.89
769_A	776_Q	0.529	0.89
435_K	438_A	0.529	0.89
313_A	496_G	0.528	0.89
235_G	238_Y	0.528	0.89
289_S	293_I	0.528	0.89
236_H	240_S	0.528	0.89
147_P	161_A	0.528	0.89
189_A	196_G	0.528	0.89
365_E	584_R	0.528	0.89
364_G	399_V	0.527	0.89
630_A	686_E	0.527	0.89
108_M	159_Y	0.527	0.89
626_A	676_N	0.527	0.89
311_S	506_R	0.527	0.89
541_F	621_E	0.526	0.89
443_V	446_V	0.526	0.89
552_L	598_H	0.525	0.89
398_S	583_F	0.525	0.89
180_A	184_R	0.525	0.89
518_D	668_R	0.525	0.89
116_R	119_N	0.524	0.89
608_L	641_A	0.524	0.89
581_N	584_R	0.524	0.89
431_Q	434_D	0.523	0.89
124_V	149_D	0.523	0.89
241_A	257_A	0.523	0.89
197_I	200_M	0.522	0.88
432_L	775_K	0.522	0.88
263_A	289_S	0.521	0.88
336_V	357_V	0.521	0.88
491_I	512_Q	0.521	0.88
109_S	134_L	0.520	0.88
427_P	507_D	0.520	0.88
756_S	759_G	0.520	0.88
302_L	489_M	0.520	0.88
319_D	338_L	0.519	0.88
227_L	231_V	0.519	0.88
813_M	817_S	0.519	0.88
734_G	747_T	0.519	0.88
220_L	223_G	0.518	0.88
107_G	160_G	0.518	0.88
193_L	196_G	0.517	0.88
349_L	399_V	0.517	0.88
603_G	636_A	0.516	0.88
454_I	459_G	0.516	0.88
372_M	390_A	0.516	0.88
113_C	134_L	0.515	0.88
391_G	402_R	0.515	0.88
389_H	411_T	0.515	0.88
354_R	390_A	0.513	0.88
678_T	681_N	0.513	0.88
490_S	494_G	0.512	0.88
111_A	134_L	0.511	0.87
253_D	300_H	0.510	0.87
311_S	746_E	0.510	0.87
785_N	816_S	0.510	0.87
556_L	595_A	0.510	0.87
785_N	806_P	0.509	0.87
449_L	453_A	0.508	0.87
210_M	214_D	0.508	0.87
287_E	810_G	0.508	0.87
105_L	134_L	0.508	0.87
196_G	202_W	0.507	0.87
625_Q	632_P	0.507	0.87
607_L	610_E	0.507	0.87
540_T	645_L	0.506	0.87
609_N	612_Q	0.506	0.87
826_R	829_R	0.506	0.87
550_L	554_A	0.505	0.87
270_V	284_L	0.505	0.87
452_A	470_I	0.505	0.87
116_R	157_A	0.505	0.87
543_D	640_K	0.504	0.87
363_Q	581_N	0.504	0.87
195_V	198_P	0.504	0.87
230_M	293_I	0.504	0.87
309_R	828_L	0.503	0.87
468_L	472_T	0.503	0.87
737_M	751_T	0.503	0.87
274_P	282_R	0.503	0.87
553_A	643_A	0.502	0.86
717_M	788_G	0.502	0.86
520_V	735_I	0.502	0.86
226_T	289_S	0.501	0.86
483_L	508_A	0.501	0.86
117_V	159_Y	0.501	0.86
117_V	139_A	0.501	0.86
107_G	137_R	0.501	0.86
691_E	704_A	0.501	0.86
449_L	452_A	0.501	0.86
444_V	481_C	0.500	0.86
559_G	602_L	0.500	0.86
200_M	204_M	0.500	0.86

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bbjA	1	0.7842	100	0.268	Contact Map
3j09A	2	0.8537	100	0.281	Contact Map
4umwA	1	0.7194	100	0.308	Contact Map
3j08A	2	0.7638	100	0.346	Contact Map
1mhsA	2	0.8165	100	0.529	Contact Map
3b8cA	1	0.7482	100	0.53	Contact Map
2zxeA	1	0.7638	100	0.548	Contact Map
3ixzA	1	0.771	100	0.55	Contact Map
3ar4A	1	0.7554	100	0.557	Contact Map
3skxA	1	0.3106	100	0.799	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0179 seconds.