MMUP - ECOLI - GREMLIN Contacts

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MMUP - Probable S-methylmethionine permease

UniProt:	Q47689	Sequences: MQTTQQNAPLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTGAAGTLLAYLIGALVVWLVMQCLGELSVAMPETGAFHVYAARYLGPATGYTVAWLYWLTWTVALGSSFTAAGFCMQYWFPQVPVWVWCVVFCAIIFGLNVISTRFFAEGEFWFSLVKVVTIIAFIILGGAAIFGFIPMQDGSPAPGLSNITAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPRKVIPVAIRTTIARLIIFFIGTVFVLAALIPMQQVGVEKSPFVLVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSLSNERTLPACFARVTKNGVPLTALSVSMLGGVLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFVFRRRHLQQGKALSELHYRAPWYPLVPVLGFVLCLVACVGLAFDPAQRIALWCGLPFVALCYGAYFLTQPRNAKQEPEHVAE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13342
Length:	467 (425)
Sequences:	24770 (16129)
Seq/√Len:	782.4

ECOLI - MMUP AROP GABP LYSP YIFK PROY CYCA ANSP PHEP PUUP PLAP FRLA GADC ADIC POTE YCAM YJEM YGJI ARCD CADB YBAT YJEH TNAB
BACSU - YBGF HUTM ROCC ROCE GABP YBXG AAPA YDGF YTNA YVBW ASPP YHDG YBEC YFNA YCGH STET ARCD YECA YDAO GERBB GERAB YNDE GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97X49 Q97WS3 Q97U05 Q97Z63 Q97XM0 Q97ZB5 Q7LXI7 Q97VA6 Q97VA8 Q97U33 Q97WD4 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
139_F	344_M	4.476	1.00
326_C	338_T	4.396	1.00
386_V	390_R	3.449	1.00
56_A	249_I	3.225	1.00
329_R	338_T	3.121	1.00
235_K	239_V	3.045	1.00
378_L	416_F	3.028	1.00
15_K	231_E	2.900	1.00
230_T	236_V	2.768	1.00
80_H	320_E	2.765	1.00
232_N	235_K	2.707	1.00
96_A	317_L	2.641	1.00
318_S	328_A	2.630	1.00
20_I	243_T	2.593	1.00
171_G	258_V	2.515	1.00
331_T	337_L	2.484	1.00
132_V	348_V	2.467	1.00
16_T	243_T	2.461	1.00
326_C	329_R	2.438	1.00
286_Y	290_I	2.382	1.00
228_G	319_N	2.351	1.00
68_E	388_R	2.288	1.00
169_I	173_A	2.227	1.00
84_A	92_G	2.203	1.00
341_S	345_L	2.200	1.00
315_W	319_N	2.186	1.00
229_E	312_R	2.152	1.00
140_G	144_I	2.151	1.00
136_A	348_V	2.136	1.00
381_C	415_G	2.103	1.00
16_T	236_V	2.099	1.00
16_T	20_I	2.095	1.00
139_F	340_L	2.090	1.00
147_R	151_E	2.089	1.00
437_W	441_P	2.079	1.00
19_L	230_T	2.074	1.00
413_V	417_V	2.072	1.00
143_V	337_L	2.055	1.00
277_L	280_E	2.026	1.00
239_V	243_T	2.010	1.00
158_L	162_V	1.996	1.00
20_I	247_R	1.983	1.00
84_A	89_P	1.965	1.00
132_V	351_L	1.964	1.00
131_C	351_L	1.956	1.00
15_K	18_H	1.954	1.00
87_L	386_V	1.936	1.00
327_F	342_V	1.933	1.00
65_C	381_C	1.931	1.00
441_P	444_A	1.919	1.00
321_R	325_A	1.914	1.00
10_L	330_V	1.904	1.00
267_Q	281_K	1.899	1.00
100_W	343_S	1.860	1.00
57_L	61_L	1.853	1.00
264_P	267_Q	1.849	1.00
87_L	382_A	1.843	1.00
39_I	48_T	1.839	1.00
242_R	246_A	1.790	1.00
441_P	445_L	1.776	1.00
136_A	344_M	1.769	1.00
232_N	236_V	1.755	1.00
410_L	414_L	1.746	1.00
331_T	335_V	1.745	1.00
447_Y	451_F	1.739	1.00
18_H	154_F	1.736	1.00
277_L	281_K	1.729	1.00
417_V	421_V	1.721	1.00
83_A	95_V	1.713	1.00
14_M	18_H	1.710	1.00
142_N	304_N	1.699	1.00
88_G	91_T	1.672	1.00
95_V	379_S	1.663	1.00
51_A	209_T	1.661	1.00
23_S	244_T	1.655	1.00
143_V	341_S	1.653	1.00
111_F	303_A	1.643	1.00
333_N	337_L	1.641	1.00
386_V	389_R	1.638	1.00
135_C	347_G	1.598	1.00
444_A	448_G	1.595	1.00
162_V	166_A	1.575	1.00
107_L	347_G	1.573	1.00
443_V	447_Y	1.558	1.00
246_A	250_I	1.553	1.00
118_M	130_W	1.539	1.00
58_V	418_L	1.514	1.00
11_K	334_G	1.513	1.00
314_L	339_A	1.507	1.00
226_A	308_Y	1.497	1.00
382_A	416_F	1.495	1.00
310_S	343_S	1.488	1.00
338_T	342_V	1.477	1.00
55_G	213_V	1.473	1.00
144_I	333_N	1.462	1.00
87_L	91_T	1.462	1.00
163_T	294_V	1.460	1.00
114_A	296_L	1.459	1.00
280_E	288_A	1.457	1.00
189_G	192_N	1.454	1.00
132_V	136_A	1.447	1.00
445_L	449_A	1.443	1.00
315_W	330_V	1.441	1.00
325_A	328_A	1.437	1.00
135_C	344_M	1.429	1.00
325_A	329_R	1.420	1.00
83_A	379_S	1.415	1.00
190_L	193_I	1.414	1.00
442_F	446_C	1.413	1.00
382_A	386_V	1.413	1.00
232_N	239_V	1.413	1.00
57_L	414_L	1.408	1.00
172_G	258_V	1.407	1.00
63_M	245_I	1.402	1.00
61_L	414_L	1.400	1.00
111_F	135_C	1.387	1.00
76_T	228_G	1.374	1.00
446_C	449_A	1.371	1.00
139_F	341_S	1.369	1.00
445_L	451_F	1.364	1.00
10_L	315_W	1.357	1.00
329_R	337_L	1.356	1.00
18_H	150_A	1.342	1.00
114_A	134_F	1.339	1.00
311_G	340_L	1.334	1.00
63_M	241_I	1.327	1.00
161_V	165_I	1.313	1.00
73_M	85_R	1.312	1.00
407_W	411_V	1.312	1.00
289_D	293_F	1.306	1.00
16_T	239_V	1.299	1.00
168_I	254_G	1.297	1.00
40_I	48_T	1.295	1.00
273_S	277_L	1.295	1.00
233_P	238_P	1.290	1.00
421_V	425_G	1.288	1.00
86_Y	383_S	1.286	1.00
236_V	239_V	1.269	1.00
14_M	19_L	1.268	1.00
27_V	248_L	1.263	1.00
17_R	21_M	1.259	1.00
250_I	254_G	1.254	1.00
435_A	439_G	1.254	1.00
433_R	436_L	1.252	1.00
49_L	257_F	1.243	1.00
314_L	323_L	1.232	1.00
138_I	303_A	1.232	1.00
171_G	262_L	1.227	1.00
47_G	206_I	1.219	1.00
280_E	285_P	1.218	1.00
81_V	85_R	1.213	1.00
175_I	261_A	1.211	1.00
62_V	381_C	1.209	1.00
128_W	132_V	1.209	1.00
439_G	443_V	1.205	1.00
65_C	412_P	1.202	1.00
64_Q	242_R	1.200	1.00
176_F	179_I	1.199	1.00
100_W	314_L	1.198	1.00
14_M	150_A	1.196	1.00
34_F	113_A	1.196	1.00
173_A	178_F	1.185	1.00
110_S	302_A	1.177	1.00
124_Q	127_V	1.169	1.00
19_L	240_A	1.168	1.00
90_A	450_Y	1.159	1.00
167_F	171_G	1.156	1.00
23_S	223_I	1.151	1.00
93_Y	97_W	1.149	1.00
416_F	420_L	1.142	1.00
408_Y	412_P	1.141	1.00
231_E	236_V	1.138	1.00
389_R	392_L	1.135	1.00
434_I	437_W	1.133	1.00
75_E	81_V	1.132	1.00
338_T	341_S	1.128	1.00
265_M	268_V	1.125	1.00
141_L	152_G	1.123	1.00
410_L	413_V	1.121	1.00
172_G	176_F	1.120	1.00
22_L	226_A	1.120	1.00
13_T	231_E	1.107	1.00
385_F	413_V	1.106	1.00
66_L	79_F	1.104	1.00
152_G	156_F	1.103	1.00
166_A	170_L	1.102	1.00
420_L	424_V	1.089	1.00
409_P	413_V	1.089	1.00
399_S	402_H	1.084	1.00
151_E	155_W	1.083	1.00
83_A	91_T	1.082	1.00
126_P	129_V	1.080	1.00
80_H	316_S	1.079	1.00
176_F	180_P	1.079	1.00
378_L	420_L	1.076	1.00
129_V	133_V	1.070	1.00
153_E	304_N	1.069	1.00
441_P	446_C	1.068	1.00
24_L	247_R	1.067	1.00
330_V	334_G	1.056	1.00
85_R	391_H	1.055	1.00
384_H	412_P	1.055	1.00
437_W	448_G	1.052	1.00
403_Y	406_P	1.048	1.00
72_A	399_S	1.044	1.00
319_N	328_A	1.042	1.00
70_S	82_Y	1.041	1.00
401_L	404_R	1.039	1.00
68_E	71_V	1.036	1.00
115_G	130_W	1.028	1.00
75_E	85_R	1.019	1.00
133_V	137_I	1.018	1.00
139_F	143_V	1.017	1.00
446_C	450_Y	1.016	1.00
72_A	401_L	1.015	1.00
447_Y	450_Y	1.012	1.00
392_L	401_L	1.007	1.00
432_Q	435_A	1.005	1.00
271_E	277_L	1.005	1.00
173_A	177_G	0.997	1.00
146_T	308_Y	0.993	1.00
227_A	237_I	0.992	1.00
345_L	349_L	0.988	1.00
118_M	122_F	0.986	1.00
429_D	433_R	0.984	1.00
24_L	248_L	0.977	1.00
407_W	410_L	0.972	1.00
136_A	140_G	0.970	1.00
189_G	194_T	0.969	1.00
427_A	430_P	0.964	1.00
440_L	444_A	0.962	1.00
156_F	301_S	0.958	1.00
125_V	129_V	0.956	1.00
433_R	437_W	0.954	1.00
434_I	441_P	0.952	1.00
307_L	344_M	0.949	1.00
161_V	251_F	0.948	1.00
430_P	433_R	0.946	1.00
165_I	169_I	0.943	1.00
143_V	335_V	0.943	1.00
437_W	444_A	0.942	1.00
207_L	421_V	0.942	1.00
423_C	426_L	0.942	1.00
427_A	431_A	0.937	1.00
137_I	300_L	0.935	1.00
21_M	154_F	0.935	1.00
177_G	180_P	0.932	1.00
138_I	304_N	0.932	1.00
436_L	439_G	0.932	1.00
378_L	419_C	0.928	1.00
193_I	196_E	0.928	1.00
218_S	373_V	0.924	1.00
283_G	287_A	0.923	1.00
119_Q	123_P	0.923	1.00
53_L	253_I	0.922	1.00
431_A	445_L	0.918	1.00
168_I	258_V	0.916	1.00
437_W	442_F	0.916	1.00
415_G	419_C	0.913	1.00
249_I	253_I	0.909	1.00
160_K	298_A	0.903	1.00
257_F	261_A	0.903	1.00
264_P	281_K	0.903	1.00
118_M	296_L	0.901	1.00
77_G	81_V	0.900	1.00
445_L	450_Y	0.900	1.00
13_T	147_R	0.898	1.00
221_E	225_I	0.897	1.00
443_V	446_C	0.897	1.00
337_L	341_S	0.897	1.00
448_G	451_F	0.890	1.00
173_A	176_F	0.887	1.00
109_S	215_F	0.886	1.00
192_N	195_A	0.885	1.00
243_T	247_R	0.884	1.00
269_G	272_K	0.883	1.00
143_V	331_T	0.883	1.00
114_A	300_L	0.881	1.00
388_R	392_L	0.880	1.00
61_L	411_V	0.879	1.00
202_G	205_P	0.876	1.00
421_V	424_V	0.876	1.00
262_L	278_V	0.872	1.00
91_T	379_S	0.870	1.00
17_R	154_F	0.868	1.00
381_C	416_F	0.864	1.00
285_P	289_D	0.862	1.00
10_L	312_R	0.862	1.00
441_P	448_G	0.861	1.00
432_Q	436_L	0.860	1.00
167_F	279_F	0.860	1.00
84_A	320_E	0.860	1.00
323_L	327_F	0.857	1.00
97_W	323_L	0.853	1.00
274_P	279_F	0.853	1.00
28_I	31_G	0.852	1.00
175_I	178_F	0.849	1.00
400_E	404_R	0.849	1.00
406_P	410_L	0.847	1.00
18_H	151_E	0.847	1.00
109_S	366_S	0.846	1.00
88_G	451_F	0.846	1.00
399_S	404_R	0.845	1.00
429_D	432_Q	0.845	1.00
49_L	260_A	0.842	1.00
151_E	154_F	0.840	1.00
438_C	442_F	0.833	1.00
130_W	133_V	0.832	1.00
331_T	334_G	0.832	1.00
60_W	64_Q	0.831	1.00
378_L	382_A	0.831	1.00
168_I	172_G	0.831	1.00
440_L	443_V	0.830	1.00
284_I	287_A	0.829	1.00
208_M	212_A	0.828	1.00
175_I	179_I	0.826	1.00
439_G	442_F	0.819	1.00
10_L	229_E	0.815	1.00
114_A	299_I	0.814	1.00
389_R	409_P	0.814	1.00
77_G	80_H	0.808	1.00
444_A	447_Y	0.808	1.00
412_P	419_C	0.807	1.00
385_F	412_P	0.807	1.00
222_L	309_A	0.806	1.00
431_A	434_I	0.805	1.00
344_M	348_V	0.804	1.00
88_G	92_G	0.798	1.00
327_F	338_T	0.798	1.00
128_W	351_L	0.798	1.00
191_S	194_T	0.797	1.00
140_G	143_V	0.797	1.00
69_L	384_H	0.790	1.00
412_P	416_F	0.789	1.00
71_V	402_H	0.788	1.00
16_T	240_A	0.785	1.00
90_A	94_T	0.781	1.00
415_G	418_L	0.781	1.00
56_A	217_F	0.781	1.00
274_P	278_V	0.781	1.00
405_A	408_Y	0.777	1.00
115_G	131_C	0.777	1.00
422_A	426_L	0.775	1.00
50_L	206_I	0.774	1.00
172_G	254_G	0.773	1.00
368_I	372_A	0.772	1.00
391_H	399_S	0.771	1.00
61_L	65_C	0.771	1.00
419_C	422_A	0.767	1.00
13_T	17_R	0.766	1.00
60_W	242_R	0.766	1.00
384_H	388_R	0.765	1.00
53_L	57_L	0.763	1.00
108_G	365_L	0.761	1.00
112_T	365_L	0.761	1.00
28_I	160_K	0.759	1.00
45_A	260_A	0.758	1.00
47_G	199_F	0.758	1.00
218_S	377_W	0.757	1.00
135_C	351_L	0.756	1.00
432_Q	445_L	0.755	1.00
83_A	383_S	0.754	1.00
383_S	387_F	0.754	1.00
409_P	412_P	0.752	1.00
203_G	206_I	0.750	1.00
175_I	180_P	0.750	1.00
430_P	434_I	0.749	1.00
385_F	389_R	0.748	1.00
138_I	307_L	0.746	1.00
144_I	148_F	0.745	1.00
273_S	276_V	0.745	1.00
279_F	282_V	0.744	1.00
115_G	118_M	0.741	1.00
32_L	255_T	0.739	1.00
437_W	440_L	0.737	1.00
17_R	151_E	0.736	1.00
29_G	33_F	0.736	1.00
99_Y	103_W	0.733	1.00
203_G	207_L	0.730	1.00
345_L	348_V	0.729	1.00
336_P	339_A	0.726	1.00
69_L	82_Y	0.720	1.00
270_V	274_P	0.719	1.00
168_I	255_T	0.718	1.00
434_I	445_L	0.718	1.00
400_E	403_Y	0.717	1.00
48_T	256_V	0.714	1.00
439_G	445_L	0.714	1.00
437_W	446_C	0.713	1.00
279_F	284_I	0.710	1.00
148_F	151_E	0.706	1.00
27_V	244_T	0.706	1.00
20_I	240_A	0.705	1.00
436_L	440_L	0.701	1.00
50_L	53_L	0.700	1.00
392_L	399_S	0.699	1.00
138_I	300_L	0.698	1.00
13_T	146_T	0.697	1.00
25_G	157_S	0.696	1.00
150_A	154_F	0.694	1.00
327_F	339_A	0.693	1.00
142_N	340_L	0.690	1.00
238_P	241_I	0.690	1.00
175_I	258_V	0.689	1.00
64_Q	406_P	0.689	1.00
435_A	442_F	0.688	1.00
132_V	352_F	0.688	1.00
62_V	419_C	0.688	1.00
199_F	206_I	0.686	1.00
128_W	131_C	0.684	1.00
134_F	303_A	0.683	1.00
104_T	346_G	0.680	1.00
80_H	84_A	0.678	1.00
66_L	380_I	0.677	1.00
106_A	369_S	0.677	1.00
435_A	445_L	0.676	1.00
86_Y	386_V	0.676	1.00
72_A	392_L	0.674	1.00
232_N	238_P	0.674	1.00
385_F	409_P	0.673	1.00
97_W	441_P	0.672	1.00
143_V	333_N	0.672	1.00
194_T	197_G	0.672	1.00
274_P	282_V	0.672	1.00
307_L	311_G	0.671	1.00
436_L	445_L	0.671	1.00
435_A	441_P	0.670	1.00
428_F	431_A	0.669	1.00
434_I	447_Y	0.668	1.00
28_I	33_F	0.667	1.00
178_F	181_M	0.664	1.00
50_L	54_I	0.663	1.00
311_G	339_A	0.662	1.00
332_K	337_L	0.662	1.00
428_F	432_Q	0.661	1.00
26_G	306_G	0.660	1.00
72_A	402_H	0.660	1.00
326_C	342_V	0.660	1.00
278_V	282_V	0.659	1.00
207_L	425_G	0.659	1.00
143_V	340_L	0.658	1.00
312_R	315_W	0.656	1.00
59_V	220_T	0.655	1.00
431_A	444_A	0.652	1.00
434_I	451_F	0.650	1.00
49_L	53_L	0.650	1.00
120_Y	123_P	0.649	1.00
142_N	308_Y	0.649	1.00
106_A	110_S	0.648	1.00
192_N	196_E	0.647	1.00
432_Q	437_W	0.647	1.00
393_Q	401_L	0.647	1.00
437_W	445_L	0.646	1.00
247_R	250_I	0.646	1.00
114_A	118_M	0.645	1.00
105_V	368_I	0.645	1.00
286_Y	289_D	0.645	1.00
314_L	342_V	0.644	1.00
52_Y	216_A	0.643	1.00
389_R	393_Q	0.643	1.00
118_M	134_F	0.640	1.00
36_T	256_V	0.639	1.00
108_G	111_F	0.638	1.00
65_C	405_A	0.638	1.00
270_V	273_S	0.637	1.00
247_R	251_F	0.637	1.00
198_W	201_H	0.636	1.00
444_A	450_Y	0.636	1.00
423_C	431_A	0.635	1.00
419_C	423_C	0.631	1.00
401_L	405_A	0.631	1.00
438_C	441_P	0.630	1.00
76_T	315_W	0.630	1.00
318_S	327_F	0.629	1.00
136_A	139_F	0.628	1.00
26_G	305_S	0.626	1.00
28_I	251_F	0.626	1.00
102_T	373_V	0.626	1.00
44_G	47_G	0.626	1.00
224_G	241_I	0.626	1.00
49_L	253_I	0.626	1.00
434_I	443_V	0.626	1.00
67_G	71_V	0.625	1.00
290_I	294_V	0.625	1.00
433_R	445_L	0.624	1.00
190_L	194_T	0.622	1.00
439_G	444_A	0.622	1.00
228_G	315_W	0.622	1.00
418_L	422_A	0.620	1.00
103_W	306_G	0.619	1.00
205_P	208_M	0.619	1.00
17_R	20_I	0.619	1.00
86_Y	387_F	0.618	1.00
80_H	96_A	0.617	1.00
254_G	258_V	0.615	1.00
38_Y	363_V	0.615	1.00
79_F	221_E	0.614	1.00
146_T	226_A	0.614	1.00
98_L	376_V	0.612	1.00
70_S	224_G	0.611	1.00
393_Q	400_E	0.611	1.00
120_Y	292_N	0.611	1.00
23_S	27_V	0.609	1.00
106_A	109_S	0.609	1.00
258_V	261_A	0.608	1.00
157_S	160_K	0.605	1.00
431_A	435_A	0.604	1.00
87_L	383_S	0.604	1.00
10_L	13_T	0.604	1.00
372_A	376_V	0.603	1.00
230_T	237_I	0.603	1.00
269_G	274_P	0.602	1.00
434_I	446_C	0.599	1.00
298_A	301_S	0.599	1.00
408_Y	411_V	0.599	1.00
39_I	43_T	0.597	1.00
135_C	348_V	0.596	1.00
237_I	241_I	0.593	1.00
433_R	444_A	0.592	1.00
69_L	86_Y	0.590	1.00
437_W	443_V	0.590	1.00
225_I	309_A	0.590	1.00
445_L	448_G	0.589	1.00
20_I	23_S	0.589	1.00
279_F	287_A	0.588	1.00
111_F	115_G	0.587	1.00
218_S	221_E	0.587	1.00
63_M	220_T	0.586	1.00
35_N	366_S	0.584	1.00
70_S	237_I	0.580	1.00
442_F	448_G	0.579	1.00
255_T	275_F	0.579	1.00
310_S	314_L	0.579	1.00
150_A	304_N	0.578	1.00
24_L	157_S	0.578	1.00
139_F	307_L	0.577	1.00
435_A	440_L	0.577	1.00
434_I	438_C	0.576	1.00
110_S	113_A	0.576	1.00
229_E	336_P	0.576	1.00
108_G	350_A	0.572	1.00
243_T	246_A	0.570	1.00
233_P	236_V	0.569	1.00
39_I	213_V	0.569	1.00
352_F	355_V	0.568	1.00
412_P	426_L	0.568	1.00
414_L	417_V	0.567	1.00
442_F	449_A	0.567	1.00
145_S	148_F	0.567	1.00
427_A	433_R	0.565	1.00
180_P	261_A	0.565	1.00
234_R	400_E	0.564	1.00
312_R	330_V	0.563	1.00
435_A	438_C	0.561	1.00
434_I	448_G	0.561	1.00
234_R	402_H	0.559	1.00
442_F	445_L	0.558	1.00
22_L	25_G	0.558	1.00
435_A	451_F	0.558	1.00
197_G	200_P	0.556	1.00
387_F	391_H	0.556	1.00
117_C	295_I	0.555	1.00
174_A	177_G	0.555	1.00
159_V	294_V	0.553	1.00
391_H	401_L	0.552	1.00
293_F	297_T	0.552	1.00
159_V	163_T	0.551	1.00
79_F	225_I	0.551	1.00
55_G	217_F	0.548	1.00
418_L	421_V	0.547	1.00
55_G	214_N	0.546	1.00
54_I	210_M	0.544	1.00
80_H	92_G	0.543	1.00
433_R	439_G	0.542	1.00
121_W	292_N	0.541	1.00
134_F	138_I	0.541	1.00
221_E	377_W	0.540	1.00
195_A	198_W	0.539	1.00
255_T	259_L	0.539	1.00
170_L	174_A	0.538	1.00
342_V	346_G	0.538	1.00
192_N	197_G	0.538	1.00
387_F	392_L	0.536	1.00
430_P	435_A	0.535	1.00
434_I	444_A	0.534	1.00
433_R	446_C	0.533	1.00
26_G	222_L	0.532	1.00
148_F	152_G	0.532	1.00
408_Y	413_V	0.531	1.00
72_A	387_F	0.531	1.00
137_I	141_L	0.531	1.00
121_W	293_F	0.530	1.00
12_R	231_E	0.530	1.00
98_L	102_T	0.530	1.00
146_T	150_A	0.528	1.00
68_E	406_P	0.527	1.00
78_A	224_G	0.527	1.00
407_W	412_P	0.526	1.00
149_F	308_Y	0.526	1.00
434_I	442_F	0.526	1.00
218_S	369_S	0.525	1.00
21_M	157_S	0.524	1.00
216_A	252_F	0.524	1.00
275_F	279_F	0.524	1.00
62_V	221_E	0.523	1.00
95_V	376_V	0.522	1.00
373_V	376_V	0.522	1.00
63_M	67_G	0.521	1.00
154_F	158_L	0.520	1.00
83_A	92_G	0.519	1.00
314_L	318_S	0.519	1.00
121_W	296_L	0.519	1.00
43_T	46_A	0.519	1.00
435_A	443_V	0.519	1.00
162_V	165_I	0.519	1.00
108_G	347_G	0.518	1.00
190_L	261_A	0.518	1.00
431_A	448_G	0.516	1.00
110_S	303_A	0.515	1.00
363_V	366_S	0.514	1.00
349_L	352_F	0.513	1.00
431_A	446_C	0.513	1.00
417_V	420_L	0.512	1.00
49_L	52_Y	0.512	1.00
110_S	299_I	0.510	1.00
104_T	343_S	0.509	1.00
170_L	284_I	0.509	1.00
52_Y	256_V	0.509	1.00
269_G	273_S	0.508	1.00
69_L	387_F	0.506	1.00
14_M	146_T	0.505	1.00
87_L	90_A	0.505	1.00
39_I	209_T	0.505	1.00
434_I	439_G	0.504	1.00
117_C	276_V	0.504	1.00
107_L	110_S	0.501	1.00
28_I	35_N	0.501	1.00
437_W	447_Y	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8929	100	0.306	Contact Map
4djkA	2	0.8779	100	0.361	Contact Map
3giaA	1	0.9101	100	0.367	Contact Map
2jlnA	1	0.9036	99	0.855	Contact Map
3dh4A	3	0.9143	98.8	0.862	Contact Map
2xq2A	2	0.9165	98.8	0.863	Contact Map
2a65A	2	0.9251	97.9	0.897	Contact Map
4wgvA	2	0.7773	97.7	0.899	Contact Map
4xp4A	1	0.9272	97.4	0.906	Contact Map
4us3A	1	0.8308	96.8	0.914	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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