GREMLIN Database
YKFG - UPF0758 protein YkfG
UniProt: Q47685 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14331
Length: 158 (150)
Sequences: 4033 (2984)
Seq/√Len: 243.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
150_Y155_H2.8161.00
92_V131_L2.6331.00
65_D69_Q2.5981.00
74_E94_R2.5911.00
105_L138_V2.5381.00
121_K152_F2.4281.00
56_R78_T2.1661.00
47_L106_A2.1121.00
72_A98_F2.0521.00
128_V138_V1.9551.00
105_L127_L1.9381.00
118_Q122_T1.9321.00
38_T42_A1.9061.00
81_I101_A1.8821.00
37_F70_L1.8531.00
60_R75_T1.7601.00
66_N82_N1.7551.00
75_T78_T1.7521.00
63_Y94_R1.7231.00
125_Q129_Q1.7181.00
124_T141_H1.6891.00
121_K157_L1.6701.00
58_E78_T1.6701.00
58_E75_T1.6511.00
41_H45_E1.5941.00
43_V104_I1.5811.00
54_L58_E1.5801.00
62_L70_L1.5681.00
93_K99_N1.5611.00
114_T148_Q1.5511.00
60_R73_H1.5491.00
77_F84_T1.5411.00
40_T154_E1.5201.00
129_Q132_Q1.4861.00
22_A26_L1.4731.00
94_R97_H1.4641.00
91_V127_L1.4541.00
63_Y98_F1.4481.00
50_H73_H1.4191.00
59_F86_V1.4031.00
10_E16_R1.3831.00
51_M54_L1.3831.00
86_V123_L1.3721.00
114_T150_Y1.3721.00
67_Q113_E1.3711.00
142_L149_I1.3631.00
118_Q121_K1.3491.00
92_V134_V1.3371.00
55_E93_K1.3321.00
95_A103_V1.3201.00
95_A136_I1.3181.00
128_V132_Q1.3131.00
44_R149_I1.2961.00
68_N102_A1.2911.00
93_K97_H1.2831.00
94_R98_F1.2551.00
150_Y157_L1.2481.00
59_F138_V1.2221.00
47_L62_L1.2141.00
44_R48_R1.1981.00
63_Y95_A1.1781.00
130_V133_L1.1461.00
152_F157_L1.1391.00
51_M60_R1.1341.00
115_T155_H1.1011.00
59_F84_T1.0991.00
37_F43_V1.0971.00
64_L102_A1.0851.00
103_V131_L1.0841.00
24_R28_R1.0821.00
52_A146_G1.0781.00
56_R77_F1.0751.00
90_E93_K1.0701.00
62_L73_H1.0701.00
24_R27_D1.0661.00
130_V134_V1.0571.00
131_L134_V1.0551.00
68_N139_P1.0401.00
54_L75_T1.0391.00
80_T90_E1.0211.00
63_Y74_E1.0171.00
48_R52_A1.0121.00
80_T87_H1.0051.00
131_L138_V0.9981.00
46_W73_H0.9981.00
13_P17_R0.9961.00
80_T85_E0.9961.00
60_R106_A0.9911.00
61_V105_L0.9761.00
63_Y100_A0.9711.00
129_Q133_L0.9671.00
37_F46_W0.9661.00
81_I89_R0.9571.00
18_L22_A0.9541.00
44_R154_E0.9461.00
10_E15_D0.9451.00
37_F42_A0.9441.00
143_I150_Y0.9431.00
39_S42_A0.9351.00
102_A139_P0.9231.00
41_H154_E0.9221.00
103_V138_V0.9191.00
125_Q128_V0.9181.00
22_A25_A0.9171.00
114_T145_G0.9041.00
16_R20_Q0.9041.00
26_L29_H0.8951.00
36_A69_Q0.8911.00
44_R142_L0.8861.00
59_F105_L0.8790.99
43_V142_L0.8770.99
23_L29_H0.8700.99
56_R90_E0.8660.99
61_V76_L0.8650.99
23_L26_L0.8640.99
43_V106_A0.8630.99
45_E48_R0.8540.99
12_T17_R0.8520.99
74_E98_F0.8520.99
15_D21_R0.8320.99
72_A94_R0.8270.99
66_N101_A0.8270.99
50_H75_T0.8250.99
63_Y72_A0.8160.99
116_P150_Y0.8100.99
48_R146_G0.8060.99
15_D18_L0.8040.99
152_F155_H0.7950.99
52_A145_G0.7910.99
114_T143_I0.7880.99
63_Y76_L0.7880.99
77_F85_E0.7840.99
71_I100_A0.7790.99
54_L78_T0.7750.99
59_F123_L0.7710.99
126_R135_D0.7680.99
132_Q137_R0.7660.99
11_M15_D0.7620.99
116_P143_I0.7620.99
21_R24_R0.7580.98
149_I154_E0.7520.98
102_A137_R0.7510.98
119_A122_T0.7490.98
121_K125_Q0.7480.98
56_R74_E0.7470.98
35_V42_A0.7380.98
64_L104_I0.7250.98
87_H90_E0.7160.98
126_R129_Q0.7120.98
47_L73_H0.7110.98
143_I157_L0.7110.98
7_L10_E0.7100.98
89_R101_A0.7100.98
23_L27_D0.7040.98
82_N101_A0.7020.98
122_T125_Q0.6840.97
30_L49_L0.6810.97
50_H60_R0.6790.97
91_V105_L0.6760.97
86_V91_V0.6700.97
22_A29_H0.6640.97
144_V149_I0.6600.96
76_L91_V0.6600.96
18_L25_A0.6570.96
10_E23_L0.6540.96
40_T44_R0.6510.96
18_L21_R0.6450.96
17_R21_R0.6420.96
21_R25_A0.6290.95
48_R147_R0.6270.95
131_L136_I0.6210.95
20_Q23_L0.6180.95
51_M144_V0.6170.95
35_V70_L0.6130.95
127_L138_V0.6110.95
84_T123_L0.6080.94
13_P18_L0.6070.94
64_L68_N0.6050.94
88_P127_L0.6020.94
36_A70_L0.5980.94
16_R19_I0.5980.94
31_H50_H0.5940.94
140_D151_S0.5910.93
122_T126_R0.5900.93
42_A45_E0.5880.93
37_F62_L0.5880.93
81_I99_N0.5870.93
55_E99_N0.5780.93
145_G148_Q0.5760.93
26_L30_L0.5710.92
126_R130_V0.5630.92
92_V138_V0.5600.92
48_R144_V0.5580.91
27_D31_H0.5520.91
51_M106_A0.5490.91
96_L100_A0.5480.91
113_E116_P0.5480.91
96_L130_V0.5470.91
63_Y103_V0.5420.90
37_F68_N0.5420.90
40_T43_V0.5410.90
55_E97_H0.5350.90
9_G15_D0.5340.90
132_Q135_D0.5340.90
21_R26_L0.5320.89
106_A142_L0.5320.89
34_G69_Q0.5260.89
121_K150_Y0.5240.89
48_R145_G0.5230.89
33_P65_D0.5230.89
88_P92_V0.5220.88
49_L52_A0.5210.88
15_D28_R0.5180.88
50_H53_A0.5180.88
42_A70_L0.5170.88
71_I98_F0.5130.88
35_V69_Q0.5120.88
68_N101_A0.5110.87
35_V45_E0.5090.87
18_L27_D0.5080.87
65_D71_I0.5060.87
67_Q111_S0.5060.87
148_Q155_H0.5050.87
96_L136_I0.5010.86
16_R25_A0.5000.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2qlcA 1 0.7975 100 0.192 Contact Map
1oi0A 1 0.6329 88.7 0.897 Contact Map
2kcqA 1 0.7152 85.3 0.902 Contact Map
2kksA 1 0.7215 84.5 0.903 Contact Map
1dgsA 1 0.2722 78.9 0.909 Contact Map
2znrA 1 0.8291 67.9 0.916 Contact Map
1jvnA 1 0.9177 57.9 0.921 Contact Map
3oqpA 2 0.6139 57.6 0.922 Contact Map
2owoA 1 0.4051 53.1 0.923 Contact Map
2duyA 1 0.3165 52.6 0.924 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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