NAC - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

NAC - Nitrogen assimilation regulatory protein nac

UniProt:	Q47005	Sequences: MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELNQQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQALSGQVSIGFAPGTAASSITMPLLQAVRAEFPEIVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQALLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAIRLRVDEAFSLRRLTAKVIGEIESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANLSPQAQAVKELLMSVISSPVMEKRQWQLVS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14265
Length:	305 (283)
Sequences:	79552 (57778)
Seq/√Len:	3434.6

ECOLI - NAC OXYR TDCA CYNR CYSB YFER YBHD AAER LYSR CBL ABGR YFIE TTDR LEUO DMLR YAFC YIAU YEIE YDCI YBDO YCAN PGRR NHAR YNFL YHJC YNEJ ILVY YDHB DSDC YEEY YAHB METR HCAR ALLS YBEF GCVA XAPR YIDZ ICIA YGFI YHAJ YJIE PERR LRHA HDFR
BACSU - YWBI CYSL YCGK GLTR ALSR YYBE GLTC YUST CITR YTLI BSDA YOFA YVBU YWQM CZCR YXJO YKUM YRAN YOAU

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
70_A	74_Q	3.598	1.00
15_I	24_V	3.333	1.00
159_Q	288_M	2.643	1.00
67_H	81_A	2.455	1.00
96_G	142_L	2.444	1.00
11_K	24_V	2.409	1.00
160_A	265_S	2.232	1.00
160_A	163_K	2.228	1.00
174_C	187_M	2.209	1.00
113_A	290_V	2.208	1.00
163_K	265_S	2.205	1.00
92_Q	124_Y	2.205	1.00
229_I	236_A	2.172	1.00
45_Q	60_A	2.127	1.00
92_Q	122_V	2.075	1.00
8_Y	35_Q	2.071	1.00
165_D	240_E	2.055	1.00
10_V	69_R	2.049	1.00
113_A	286_L	2.022	1.00
163_K	263_S	2.006	1.00
67_H	74_Q	1.988	1.00
20_Q	23_E	1.986	1.00
167_F	240_E	1.981	1.00
10_V	14_D	1.980	1.00
230_A	251_N	1.979	1.00
11_K	15_I	1.924	1.00
180_D	183_A	1.923	1.00
94_S	124_Y	1.923	1.00
11_K	14_D	1.889	1.00
10_V	65_Y	1.888	1.00
226_T	246_L	1.880	1.00
170_G	255_S	1.860	1.00
230_A	246_L	1.860	1.00
14_D	69_R	1.832	1.00
13_V	57_P	1.823	1.00
71_I	75_C	1.821	1.00
65_Y	69_R	1.806	1.00
8_Y	32_L	1.804	1.00
190_F	234_G	1.797	1.00
167_F	254_M	1.766	1.00
188_N	216_I	1.744	1.00
49_I	56_T	1.694	1.00
63_I	81_A	1.679	1.00
158_S	267_S	1.671	1.00
136_K	141_Q	1.658	1.00
13_V	65_Y	1.653	1.00
64_L	78_A	1.624	1.00
15_I	20_Q	1.603	1.00
157_S	272_A	1.591	1.00
18_L	36_V	1.546	1.00
67_H	70_A	1.538	1.00
10_V	68_A	1.533	1.00
159_Q	270_L	1.509	1.00
135_E	139_N	1.505	1.00
17_S	20_Q	1.500	1.00
14_D	24_V	1.489	1.00
5_R	42_E	1.477	1.00
5_R	38_T	1.468	1.00
5_R	35_Q	1.451	1.00
9_F	65_Y	1.440	1.00
88_A	120_E	1.437	1.00
11_K	25_L	1.436	1.00
46_Q	49_I	1.433	1.00
114_V	283_V	1.433	1.00
284_K	288_M	1.433	1.00
8_Y	27_I	1.431	1.00
147_I	269_N	1.421	1.00
67_H	77_Q	1.417	1.00
176_G	183_A	1.415	1.00
157_S	270_L	1.413	1.00
28_A	31_A	1.403	1.00
270_L	284_K	1.397	1.00
51_T	56_T	1.388	1.00
19_T	29_Q	1.386	1.00
104_S	223_A	1.386	1.00
136_K	142_L	1.367	1.00
117_E	286_L	1.366	1.00
282_A	285_E	1.365	1.00
114_V	121_I	1.363	1.00
74_Q	77_Q	1.362	1.00
149_E	267_S	1.362	1.00
94_S	126_H	1.359	1.00
59_D	62_K	1.350	1.00
276_L	280_A	1.346	1.00
90_S	120_E	1.346	1.00
137_L	145_A	1.333	1.00
199_R	203_D	1.332	1.00
113_A	117_E	1.324	1.00
172_Q	251_N	1.321	1.00
164_E	241_S	1.319	1.00
71_I	78_A	1.315	1.00
10_V	72_L	1.307	1.00
64_L	79_Q	1.294	1.00
268_L	284_K	1.286	1.00
138_I	155_G	1.281	1.00
66_T	70_A	1.280	1.00
225_L	236_A	1.262	1.00
227_A	230_A	1.260	1.00
187_M	235_V	1.256	1.00
172_Q	253_W	1.256	1.00
67_H	78_A	1.249	1.00
170_G	235_V	1.246	1.00
246_L	251_N	1.246	1.00
144_M	268_L	1.240	1.00
160_A	267_S	1.229	1.00
115_R	216_I	1.224	1.00
115_R	188_N	1.216	1.00
42_E	79_Q	1.214	1.00
112_Q	116_A	1.213	1.00
240_E	254_M	1.212	1.00
63_I	66_T	1.207	1.00
3_F	75_C	1.203	1.00
27_I	31_A	1.202	1.00
144_M	280_A	1.192	1.00
244_R	248_G	1.189	1.00
34_Q	38_T	1.179	1.00
177_Q	253_W	1.176	1.00
112_Q	231_S	1.173	1.00
175_P	187_M	1.170	1.00
158_S	269_N	1.162	1.00
170_G	174_C	1.151	1.00
178_S	258_T	1.151	1.00
9_F	48_L	1.150	1.00
9_F	13_V	1.141	1.00
240_E	244_R	1.136	1.00
128_N	136_K	1.132	1.00
63_I	67_H	1.128	1.00
109_P	231_S	1.118	1.00
62_K	66_T	1.115	1.00
124_Y	218_E	1.110	1.00
118_F	282_A	1.106	1.00
179_V	183_A	1.105	1.00
254_M	257_I	1.101	1.00
34_Q	37_A	1.101	1.00
286_L	290_V	1.093	1.00
188_N	214_K	1.092	1.00
6_L	68_A	1.089	1.00
37_A	41_G	1.089	1.00
159_Q	284_K	1.088	1.00
113_A	116_A	1.082	1.00
70_A	77_Q	1.081	1.00
285_E	288_M	1.073	1.00
11_K	21_A	1.072	1.00
226_T	230_A	1.070	1.00
169_V	254_M	1.067	1.00
227_A	231_S	1.056	1.00
138_I	153_V	1.053	1.00
71_I	74_Q	1.049	1.00
281_Q	285_E	1.042	1.00
103_A	127_E	1.041	1.00
18_L	55_V	1.039	1.00
110_L	287_L	1.033	1.00
245_S	249_A	1.026	1.00
165_D	263_S	1.025	1.00
33_S	37_A	1.025	1.00
79_Q	83_H	1.019	1.00
73_R	77_Q	1.018	1.00
9_F	47_L	1.014	1.00
35_Q	38_T	1.009	1.00
114_V	286_L	1.002	1.00
171_T	232_G	0.999	1.00
219_I	225_L	0.999	1.00
126_H	136_K	0.997	1.00
286_L	289_S	0.994	1.00
12_I	21_A	0.992	1.00
206_F	211_L	0.981	1.00
4_R	7_K	0.976	1.00
200_L	203_D	0.976	1.00
64_L	68_A	0.975	1.00
181_V	259_T	0.975	1.00
93_V	283_V	0.969	1.00
191_L	215_V	0.967	1.00
169_V	243_A	0.965	1.00
190_F	225_L	0.963	1.00
38_T	41_G	0.959	1.00
12_I	18_L	0.949	1.00
114_V	118_F	0.943	1.00
76_E	79_Q	0.941	1.00
13_V	48_L	0.939	1.00
27_I	32_L	0.938	1.00
76_E	80_L	0.934	1.00
7_K	76_E	0.933	1.00
168_L	235_V	0.929	1.00
8_Y	25_L	0.926	1.00
200_L	204_E	0.925	1.00
136_K	139_N	0.922	1.00
21_A	32_L	0.922	1.00
57_P	61_G	0.920	1.00
20_Q	24_V	0.913	1.00
9_F	57_P	0.912	1.00
219_I	228_A	0.911	1.00
9_F	39_L	0.905	1.00
70_A	73_R	0.903	1.00
277_S	280_A	0.902	1.00
110_L	286_L	0.898	1.00
170_G	175_P	0.898	1.00
117_E	289_S	0.897	1.00
149_E	265_S	0.879	1.00
16_G	56_T	0.878	1.00
96_G	145_A	0.873	1.00
99_P	221_S	0.871	1.00
45_Q	82_V	0.871	1.00
75_C	79_Q	0.868	1.00
48_L	55_V	0.863	1.00
66_T	69_R	0.862	1.00
246_L	249_A	0.855	1.00
157_S	160_A	0.853	1.00
122_V	214_K	0.853	1.00
19_T	23_E	0.850	1.00
134_N	138_I	0.849	1.00
188_N	215_V	0.847	1.00
112_Q	233_M	0.844	1.00
142_L	145_A	0.839	1.00
205_A	209_R	0.838	1.00
51_T	54_G	0.835	1.00
96_G	147_I	0.832	1.00
271_P	274_A	0.832	1.00
126_H	142_L	0.830	1.00
25_L	32_L	0.828	1.00
121_I	279_Q	0.827	1.00
183_A	186_Q	0.824	1.00
60_A	63_I	0.821	1.00
110_L	290_V	0.819	1.00
182_N	185_A	0.817	1.00
91_G	279_Q	0.817	1.00
95_I	144_M	0.817	1.00
115_R	233_M	0.817	1.00
77_Q	81_A	0.815	1.00
180_D	258_T	0.809	1.00
276_L	281_Q	0.808	1.00
156_V	269_N	0.806	1.00
285_E	289_S	0.804	1.00
13_V	16_G	0.803	1.00
74_Q	78_A	0.801	1.00
75_C	78_A	0.800	1.00
63_I	85_V	0.799	1.00
13_V	61_G	0.798	1.00
60_A	82_V	0.797	1.00
278_P	282_A	0.797	1.00
16_G	62_K	0.793	1.00
14_D	65_Y	0.791	1.00
15_I	21_A	0.790	1.00
9_F	64_L	0.790	1.00
169_V	236_A	0.788	1.00
165_D	261_S	0.781	1.00
165_D	256_R	0.781	1.00
29_Q	33_S	0.781	1.00
174_C	188_N	0.776	1.00
16_G	54_G	0.775	1.00
7_K	11_K	0.775	1.00
4_R	35_Q	0.774	1.00
37_A	46_Q	0.767	1.00
170_G	253_W	0.762	1.00
189_L	213_A	0.759	1.00
171_T	233_M	0.759	1.00
69_R	73_R	0.758	1.00
171_T	174_C	0.756	1.00
3_F	72_L	0.748	1.00
205_A	208_L	0.747	1.00
12_I	48_L	0.747	1.00
62_K	65_Y	0.745	1.00
228_A	233_M	0.743	1.00
5_R	8_Y	0.743	1.00
78_A	82_V	0.742	1.00
83_H	86_G	0.741	1.00
204_E	208_L	0.738	1.00
60_A	85_V	0.736	1.00
155_G	272_A	0.735	1.00
185_A	211_L	0.734	1.00
144_M	283_V	0.734	1.00
169_V	247_C	0.732	1.00
221_S	224_T	0.731	1.00
117_E	282_A	0.727	1.00
140_H	271_P	0.726	1.00
113_A	289_S	0.726	1.00
18_L	32_L	0.726	1.00
68_A	71_I	0.725	1.00
49_I	58_T	0.725	1.00
202_V	206_F	0.723	1.00
169_V	238_L	0.723	1.00
97_F	103_A	0.720	1.00
178_S	256_R	0.720	1.00
114_V	282_A	0.716	1.00
91_G	121_I	0.716	1.00
12_I	32_L	0.714	1.00
138_I	156_V	0.713	1.00
282_A	286_L	0.706	1.00
243_A	246_L	0.704	1.00
247_C	250_V	0.703	1.00
59_D	63_I	0.702	1.00
247_C	254_M	0.701	1.00
7_K	10_V	0.701	1.00
143_D	280_A	0.699	1.00
201_R	205_A	0.695	1.00
60_A	64_L	0.691	1.00
89_L	118_F	0.690	1.00
104_S	227_A	0.689	1.00
239_P	242_A	0.688	1.00
12_I	36_V	0.682	1.00
94_S	143_D	0.681	1.00
49_I	54_G	0.679	1.00
56_T	62_K	0.676	1.00
173_D	232_G	0.675	1.00
193_S	218_E	0.674	1.00
31_A	35_Q	0.673	1.00
204_E	207_S	0.672	1.00
94_S	142_L	0.671	1.00
64_L	82_V	0.668	1.00
67_H	71_I	0.662	1.00
198_I	202_V	0.657	1.00
57_P	62_K	0.657	1.00
192_P	225_L	0.657	1.00
73_R	76_E	0.654	1.00
274_A	277_S	0.648	1.00
182_N	209_R	0.648	1.00
180_D	259_T	0.646	1.00
77_Q	80_L	0.646	1.00
168_L	237_V	0.645	1.00
23_E	26_H	0.644	1.00
109_P	112_Q	0.641	1.00
217_G	228_A	0.635	1.00
203_D	207_S	0.635	1.00
278_P	281_Q	0.635	1.00
243_A	247_C	0.631	1.00
7_K	72_L	0.629	1.00
127_E	220_E	0.629	1.00
122_V	218_E	0.628	1.00
201_R	204_E	0.628	1.00
173_D	253_W	0.628	1.00
40_E	45_Q	0.626	1.00
186_Q	214_K	0.623	1.00
202_V	205_A	0.622	1.00
245_S	248_G	0.621	1.00
189_L	235_V	0.618	1.00
144_M	284_K	0.617	1.00
97_F	107_T	0.615	1.00
109_P	113_A	0.614	1.00
107_T	110_L	0.614	1.00
9_F	61_G	0.612	1.00
40_E	50_R	0.611	1.00
148_Y	264_L	0.607	1.00
168_L	184_I	0.607	1.00
4_R	38_T	0.607	1.00
80_L	84_N	0.604	1.00
36_V	40_E	0.604	1.00
99_P	129_S	0.600	1.00
172_Q	250_V	0.597	1.00
193_S	220_E	0.594	1.00
174_C	235_V	0.593	1.00
199_R	218_E	0.589	1.00
68_A	72_L	0.588	1.00
12_I	17_S	0.586	1.00
43_L	64_L	0.585	1.00
93_V	144_M	0.584	1.00
21_A	25_L	0.583	1.00
203_D	206_F	0.582	1.00
72_L	76_E	0.582	1.00
118_F	121_I	0.579	1.00
4_R	8_Y	0.578	1.00
93_V	279_Q	0.575	1.00
176_G	179_V	0.574	1.00
48_L	57_P	0.573	1.00
270_L	281_Q	0.573	1.00
45_Q	49_I	0.573	1.00
206_F	213_A	0.571	1.00
43_L	82_V	0.571	1.00
90_S	122_V	0.570	1.00
31_A	34_Q	0.568	1.00
164_E	264_L	0.566	1.00
63_I	82_V	0.566	1.00
96_G	126_H	0.563	1.00
161_L	268_L	0.563	1.00
283_V	287_L	0.562	1.00
137_L	156_V	0.562	1.00
219_I	224_T	0.559	1.00
162_L	266_L	0.558	1.00
13_V	62_K	0.558	1.00
166_L	237_V	0.554	1.00
200_L	205_A	0.552	1.00
96_G	128_N	0.550	1.00
230_A	249_A	0.549	1.00
18_L	29_Q	0.546	1.00
91_G	120_E	0.546	1.00
127_E	221_S	0.545	1.00
149_E	158_S	0.542	1.00
102_A	106_I	0.541	1.00
30_P	34_Q	0.541	1.00
137_L	269_N	0.539	1.00
225_L	229_I	0.539	1.00
80_L	83_H	0.539	1.00
43_L	46_Q	0.538	1.00
238_L	243_A	0.537	1.00
27_I	35_Q	0.535	1.00
157_S	273_R	0.533	1.00
194_D	218_E	0.533	1.00
109_P	227_A	0.532	1.00
198_I	201_R	0.531	1.00
168_L	189_L	0.531	1.00
28_A	34_Q	0.530	1.00
108_M	112_Q	0.529	1.00
228_A	234_G	0.529	1.00
18_L	54_G	0.528	1.00
57_P	65_Y	0.528	1.00
199_R	205_A	0.527	1.00
106_I	110_L	0.526	1.00
97_F	125_L	0.524	1.00
46_Q	60_A	0.523	1.00
146_V	287_L	0.523	1.00
84_N	89_L	0.521	1.00
8_Y	36_V	0.521	1.00
16_G	55_V	0.521	1.00
66_T	81_A	0.516	1.00
182_N	211_L	0.515	1.00
222_I	239_P	0.512	1.00
197_A	200_L	0.512	1.00
78_A	81_A	0.511	1.00
81_A	84_N	0.511	1.00
45_Q	86_G	0.511	1.00
122_V	216_I	0.510	1.00
138_I	141_Q	0.510	1.00
8_Y	21_A	0.506	1.00
112_Q	115_R	0.506	1.00
280_A	284_K	0.502	1.00
71_I	79_Q	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2esnA	3	0.9541	100	0.093	Contact Map
3fxqA	3	0.9541	100	0.094	Contact Map
1uthA	2	0.7377	100	0.095	Contact Map
4x6gA	4	0.9836	100	0.097	Contact Map
1ixcA	4	0.9475	100	0.099	Contact Map
3fzvA	4	0.9311	100	0.1	Contact Map
2h98A	2	0.6852	100	0.106	Contact Map
1al3A	1	0.7148	100	0.112	Contact Map
2h9bA	2	0.6885	100	0.113	Contact Map
3szpA	3	0.941	100	0.118	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0106 seconds.