GREMLIN Database
YQCC - Uncharacterized protein YqcC
UniProt: Q46919 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13172
Length: 109 (100)
Sequences: 494 (381)
Seq/√Len: 38.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_F45_M4.1731.00
81_M84_A3.6311.00
15_E19_R3.3181.00
47_P78_Y2.8761.00
47_P79_Y2.8211.00
41_F54_V2.7551.00
38_Q42_M2.5501.00
25_R49_E2.4651.00
61_D65_N2.3071.00
36_S43_D2.1330.99
59_M75_V1.9400.98
13_A99_K1.9370.98
15_E60_H1.8800.98
21_H93_I1.8760.98
14_L56_I1.8130.97
55_L59_M1.7780.97
60_H64_D1.7070.96
8_R60_H1.6390.95
73_F79_Y1.5140.93
18_L51_L1.5020.93
73_F104_F1.4920.92
51_L97_L1.4140.90
31_P95_A1.3980.90
76_A94_L1.3770.89
53_W82_A1.3650.89
53_W78_Y1.3640.89
53_W79_Y1.3630.88
14_L100_L1.3570.88
59_M62_L1.3420.88
12_Q60_H1.3260.87
8_R63_L1.2890.85
47_P53_W1.2840.85
7_V14_L1.2250.82
30_Q35_N1.1630.79
55_L100_L1.1570.79
8_R64_D1.1470.78
10_Q13_A1.1330.77
7_V100_L1.1290.77
38_Q45_M1.1250.77
86_D89_Q1.1160.76
17_L20_E1.1080.76
47_P73_F1.1080.76
10_Q14_L1.1070.75
14_L93_I1.0990.75
38_Q47_P1.0670.73
76_A98_E1.0420.71
49_E53_W0.9900.67
16_A20_E0.9890.67
73_F78_Y0.9870.67
18_L59_M0.9820.66
11_L18_L0.9780.66
61_D64_D0.9690.65
62_L104_F0.9680.65
55_L73_F0.9550.64
55_L104_F0.9540.64
96_E101_D0.9460.63
30_Q34_F0.9380.63
7_V104_F0.9380.63
25_R48_L0.9070.60
53_W73_F0.9060.60
35_N41_F0.8990.59
48_L83_L0.8970.59
14_L96_E0.8910.59
53_W57_P0.8890.58
61_D67_Q0.8790.58
54_V61_D0.8750.57
53_W80_E0.8730.57
41_F81_M0.8200.52
17_L93_I0.8120.52
22_Q27_D0.7950.50
94_L97_L0.7900.50
63_L66_K0.7840.49
28_E52_Q0.7750.48
79_Y104_F0.7680.48
78_Y82_A0.7560.47
9_L41_F0.7530.46
27_D80_E0.7410.45
63_L95_A0.7310.44
46_E86_D0.7270.44
27_D35_N0.7260.44
8_R62_L0.7190.43
45_M52_Q0.7110.43
15_E20_E0.7090.43
83_L89_Q0.7090.43
58_R61_D0.6950.41
35_N56_I0.6910.41
21_H85_T0.6910.41
7_V103_L0.6890.41
17_L83_L0.6850.40
65_N68_P0.6820.40
31_P37_T0.6800.40
30_Q68_P0.6710.39
93_I103_L0.6690.39
23_H66_K0.6590.38
76_A102_A0.6560.38
8_R12_Q0.6560.38
23_H48_L0.6550.38
25_R62_L0.6550.38
9_L12_Q0.6360.36
72_A104_F0.6350.36
19_R56_I0.6350.36
42_M81_M0.6330.36
8_R100_L0.6310.36
74_A78_Y0.6310.36
25_R78_Y0.6300.36
75_V97_L0.6270.36
21_H96_E0.6260.35
26_N45_M0.6250.35
38_Q41_F0.6250.35
56_I63_L0.6190.35
43_D101_D0.6080.34
89_Q102_A0.6010.33
71_G85_T0.5990.33
73_F77_P0.5960.33
75_V83_L0.5950.33
34_F54_V0.5910.33
98_E102_A0.5890.32
79_Y97_L0.5890.32
37_T98_E0.5830.32
19_R58_R0.5770.32
100_L104_F0.5730.31
37_T43_D0.5710.31
52_Q78_Y0.5650.31
89_Q93_I0.5640.31
76_A97_L0.5630.30
7_V72_A0.5610.30
9_L21_H0.5530.30
79_Y101_D0.5510.30
34_F42_M0.5470.29
24_W56_I0.5460.29
88_P95_A0.5440.29
9_L13_A0.5420.29
19_R24_W0.5400.29
71_G88_P0.5370.29
53_W77_P0.5350.28
29_P53_W0.5350.28
58_R64_D0.5210.27
18_L76_A0.5190.27
56_I91_A0.5170.27
73_F100_L0.5150.27
41_F83_L0.5090.27
46_E71_G0.5090.27
29_P45_M0.5080.26
21_H56_I0.5070.26
26_N52_Q0.5040.26
10_Q81_M0.5040.26
68_P98_E0.5030.26
15_E31_P0.5020.26
52_Q57_P0.5000.26
64_D100_L0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2hgkA 1 1 100 0.056 Contact Map
2dulA 2 0.7248 12.9 0.936 Contact Map
1x1nA 2 0.844 4.7 0.948 Contact Map
4s3qA 1 0.844 4.5 0.948 Contact Map
3m91B 1 0.2844 4.1 0.949 Contact Map
1eswA 1 0.8991 3.9 0.95 Contact Map
1tz7A 4 0.8991 3.8 0.95 Contact Map
4qmgA 3 0.2844 3.8 0.95 Contact Map
4c7nB 1 0.2018 3.7 0.95 Contact Map
3axsA 2 0.7615 3.5 0.951 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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