GREMLIN Database
YGCR - Putative electron transfer flavoprotein subunit YgcR
UniProt: Q46908 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13125
Length: 259 (239)
Sequences: 3528 (2044)
Seq/√Len: 132.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
159_F174_R4.3081.00
62_S87_E3.8651.00
135_P182_A3.3601.00
55_R86_E3.3351.00
110_E113_H3.3211.00
152_R163_E3.0081.00
77_L88_A2.9911.00
114_Q210_K2.9781.00
65_A80_L2.7161.00
50_L53_A2.6501.00
87_E208_I2.6251.00
2_N62_S2.4401.00
147_F175_V2.4191.00
50_L189_V2.2961.00
122_T138_L2.2411.00
81_M88_A2.2301.00
4_L112_Q2.1961.00
49_A192_P2.1771.00
150_V162_L2.1601.00
161_T174_R2.0441.00
150_V181_I2.0341.00
57_N61_M2.0301.00
40_L76_W2.0181.00
154_T161_T2.0081.00
175_V179_A1.9881.00
109_A113_H1.9751.00
160_I175_V1.9281.00
64_T89_V1.8961.00
48_A85_F1.8641.00
91_L107_H1.8491.00
6_A122_T1.8041.00
24_A28_K1.7941.00
160_I177_L1.7651.00
164_Q171_R1.7651.00
119_L179_A1.7641.00
41_G44_E1.7501.00
120_I144_W1.7501.00
74_L78_R1.7421.00
64_T87_E1.7181.00
236_I244_K1.7101.00
71_E92_E1.7091.00
67_S73_A1.7031.00
105_A141_M1.6881.00
125_Q130_Q1.6571.00
246_Q250_Q1.6501.00
4_L117_L1.6401.00
155_L160_I1.6401.00
58_G61_M1.6381.00
234_T251_D1.6351.00
163_E172_C1.6231.00
234_T247_K1.6161.00
114_Q208_I1.6111.00
99_F107_H1.5851.00
65_A85_F1.5631.00
91_L111_W1.5631.00
63_L85_F1.5491.00
183_V188_E1.5271.00
241_V245_A1.5191.00
247_K250_Q1.5151.00
112_Q120_I1.5001.00
195_G198_Q1.4451.00
66_L111_W1.4201.00
89_V111_W1.4071.00
139_A146_C1.4061.00
3_I60_P1.3901.00
95_A213_A1.3681.00
92_E209_R1.3651.00
242_A245_A1.3321.00
64_T117_L1.3311.00
57_N60_P1.3281.00
2_N64_T1.2921.00
74_L209_R1.2841.00
90_L209_R1.2831.00
54_Q59_T1.2791.00
70_D73_A1.2701.00
159_F176_R1.2661.00
161_T172_C1.2651.00
51_L63_L1.2391.00
158_L176_R1.2381.00
151_E163_E1.2341.00
118_D158_L1.2341.00
106_R110_E1.2311.00
65_A77_L1.2121.00
24_A29_S1.2010.99
156_D161_T1.1890.99
26_Q29_S1.1700.99
92_E211_T1.1660.99
50_L188_E1.1620.99
144_W180_V1.1560.99
46_A189_V1.1460.99
50_L153_F1.1400.99
126_S129_G1.1380.99
109_A142_L1.1220.99
237_D243_E1.1110.99
112_Q138_L1.1100.99
60_P63_L1.1080.99
108_I138_L1.1010.99
81_M205_A1.1000.99
40_L80_L1.0980.99
197_R201_A1.0930.99
89_V210_K1.0820.99
4_L66_L1.0750.99
32_D35_L1.0740.99
245_A249_W1.0720.99
52_L198_Q1.0700.99
106_R141_M1.0680.99
147_F162_L1.0680.99
156_D159_F1.0650.99
48_A83_L1.0640.99
155_L177_L1.0630.99
67_S90_L1.0470.99
49_A53_A1.0320.98
2_N116_P1.0260.98
136_F146_C1.0250.98
103_F217_P1.0130.98
71_E74_L1.0090.98
199_R205_A1.0030.98
43_D124_C0.9990.98
110_E114_Q0.9890.98
49_A191_L0.9840.98
50_L152_R0.9780.98
247_K251_D0.9730.98
25_A28_K0.9700.98
93_T99_F0.9660.98
109_A138_L0.9660.98
7_F80_L0.9620.98
102_E106_R0.9610.98
7_F48_A0.9570.97
214_A217_P0.9570.97
68_M104_V0.9500.97
137_L141_M0.9500.97
9_A76_W0.9490.97
121_I183_V0.9480.97
166_T169_G0.9410.97
153_F162_L0.9410.97
121_I181_I0.9410.97
52_L83_L0.9360.97
100_A218_A0.9280.97
96_D100_A0.9170.97
113_H116_P0.9120.97
7_F76_W0.9090.97
163_E170_L0.9090.97
197_R200_M0.9070.96
74_L207_I0.9060.96
55_R61_M0.9050.96
249_W252_Y0.8990.96
200_M203_G0.8990.96
153_F160_I0.8960.96
132_G136_F0.8920.96
95_A212_V0.8840.96
105_A137_L0.8820.96
45_Q83_L0.8820.96
68_M96_D0.8790.96
47_A183_V0.8760.96
107_H212_V0.8730.96
45_Q79_Y0.8720.96
122_T180_V0.8710.96
112_Q142_L0.8660.95
145_P179_A0.8640.95
111_W210_K0.8600.95
83_L191_L0.8510.95
6_A108_I0.8500.95
73_A90_L0.8480.95
126_S130_Q0.8470.95
13_A39_L0.8420.95
6_A138_L0.8420.95
7_F65_A0.8360.94
33_I70_D0.8300.94
74_L90_L0.8290.94
117_L144_W0.8280.94
87_E115_N0.8270.94
93_T96_D0.8260.94
120_I138_L0.8230.94
226_R229_Q0.8230.94
5_L63_L0.8220.94
154_T163_E0.8200.94
136_F148_T0.8130.94
53_A192_P0.8100.94
244_K252_Y0.8070.93
230_R233_A0.8040.93
96_D99_F0.7970.93
124_C130_Q0.7930.93
6_A112_Q0.7910.93
193_V199_R0.7900.93
140_E146_C0.7900.93
83_L194_P0.7870.93
79_Y83_L0.7870.93
243_E247_K0.7860.92
101_P137_L0.7810.92
241_V244_K0.7770.92
147_F173_C0.7740.92
51_L121_I0.7710.92
58_G154_T0.7650.91
214_A218_A0.7600.91
70_D90_L0.7590.91
43_D46_A0.7570.91
124_C185_Q0.7550.91
243_E246_Q0.7500.91
11_P33_I0.7490.91
146_C180_V0.7490.91
30_G221_C0.7450.90
4_L115_N0.7400.90
5_L51_L0.7390.90
99_F103_F0.7390.90
39_L127_S0.7360.90
93_T212_V0.7310.89
78_R203_G0.7300.89
200_M204_K0.7290.89
46_A184_R0.7270.89
40_L45_Q0.7260.89
100_A103_F0.7240.89
112_Q117_L0.7150.88
221_C224_L0.7130.88
244_K249_W0.7080.88
100_A217_P0.7060.88
40_L79_Y0.7050.88
119_L160_I0.7040.88
96_D107_H0.6980.87
47_A121_I0.6910.87
88_A207_I0.6890.87
156_D174_R0.6860.86
127_S130_Q0.6860.86
66_L108_I0.6840.86
202_A205_A0.6830.86
48_A65_A0.6820.86
103_F216_M0.6800.86
28_K225_A0.6790.86
5_L47_A0.6750.85
102_E218_A0.6750.85
3_I63_L0.6740.85
41_G127_S0.6730.85
72_R75_H0.6710.85
12_D39_L0.6690.85
99_F104_V0.6680.85
38_S72_R0.6670.85
131_N219_M0.6670.85
138_L180_V0.6670.85
68_M91_L0.6650.85
124_C184_R0.6630.84
113_H143_G0.6620.84
220_Q223_Q0.6570.84
122_T135_P0.6530.83
68_M99_F0.6530.83
57_N192_P0.6490.83
112_Q115_N0.6470.83
9_A38_S0.6450.83
104_V129_G0.6440.83
101_P129_G0.6370.82
12_D37_R0.6360.82
54_Q119_L0.6350.82
89_V208_I0.6340.82
101_P133_Q0.6340.82
201_A205_A0.6330.82
165_R184_R0.6290.81
11_P36_L0.6270.81
48_A52_L0.6260.81
44_E131_N0.6240.81
139_A180_V0.6210.80
153_F181_I0.6190.80
164_Q173_C0.6180.80
77_L90_L0.6140.80
147_F160_I0.6130.79
44_E129_G0.6080.79
119_L181_I0.6060.79
124_C149_Q0.6030.78
48_A183_V0.6000.78
102_E141_M0.5990.78
232_G235_L0.5990.78
160_I181_I0.5980.78
228_E231_R0.5950.77
244_K251_D0.5950.77
149_Q184_R0.5950.77
57_N154_T0.5940.77
111_W115_N0.5920.77
59_T158_L0.5910.77
77_L207_I0.5910.77
112_Q144_W0.5850.76
67_S77_L0.5830.76
80_L85_F0.5820.76
82_A198_Q0.5820.76
213_A242_A0.5810.76
212_V215_E0.5810.76
112_Q180_V0.5780.75
17_A32_D0.5750.75
99_F216_M0.5750.75
145_P175_V0.5740.75
113_H142_L0.5720.75
13_A42_A0.5700.74
236_I247_K0.5690.74
59_T155_L0.5690.74
82_A202_A0.5690.74
162_L179_A0.5680.74
152_R172_C0.5670.74
64_T115_N0.5650.74
126_S131_N0.5640.74
99_F217_P0.5640.74
217_P221_C0.5580.73
68_M108_I0.5570.73
78_R207_I0.5560.73
54_Q121_I0.5550.72
3_I6_A0.5550.72
8_K67_S0.5540.72
151_E165_R0.5540.72
43_D130_Q0.5540.72
15_M36_L0.5540.72
100_A219_M0.5530.72
121_I153_F0.5510.72
107_H111_W0.5500.72
52_L192_P0.5480.71
150_V153_F0.5470.71
83_L204_K0.5470.71
231_R234_T0.5450.71
109_A141_M0.5440.71
102_E135_P0.5380.70
133_Q137_L0.5360.70
175_V181_I0.5360.70
236_I251_D0.5350.70
2_N117_L0.5350.70
105_A138_L0.5350.70
47_A123_G0.5350.70
117_L120_I0.5340.70
78_R206_E0.5290.69
9_A69_G0.5280.69
92_E99_F0.5270.69
101_P131_N0.5270.69
11_P17_A0.5270.69
68_M100_A0.5260.68
30_G33_I0.5240.68
9_A72_R0.5240.68
48_A80_L0.5230.68
136_F182_A0.5210.68
132_G149_Q0.5210.68
125_Q132_G0.5170.67
46_A185_Q0.5150.67
69_G80_L0.5150.67
206_E250_Q0.5140.67
44_E76_W0.5140.67
225_A228_E0.5130.67
50_L183_V0.5120.66
60_P155_L0.5120.66
29_S33_I0.5110.66
46_A165_R0.5110.66
196_M203_G0.5110.66
28_K32_D0.5110.66
205_A208_I0.5100.66
32_D36_L0.5100.66
206_E209_R0.5090.66
25_A32_D0.5080.66
33_I92_E0.5070.66
234_T237_D0.5050.65
42_A124_C0.5050.65
71_E94_A0.5030.65
24_A32_D0.5030.65
86_E205_A0.5020.65
130_Q146_C0.5010.65
121_I188_E0.5010.65
3_I121_I0.5000.65
101_P126_S0.5000.65
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4l2iB 1 0.9653 100 0.205 Contact Map
1o97C 1 0.9151 100 0.207 Contact Map
1efpB 1 0.9266 100 0.236 Contact Map
1efvB 1 0.9498 100 0.254 Contact Map
3ih5A 6 0.749 100 0.613 Contact Map
4l2iA 1 0.8919 100 0.621 Contact Map
1o97D 1 0.8301 100 0.63 Contact Map
1efvA 1 0.8263 99.9 0.659 Contact Map
1efpA 1 0.8069 99.9 0.662 Contact Map
3fetA 2 0.6293 99.9 0.68 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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