GREMLIN Database
YGCQ - Putative electron transfer flavoprotein subunit YgcQ
UniProt: Q46907 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13124
Length: 286 (274)
Sequences: 4076 (2432)
Seq/√Len: 146.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
268_D273_V4.9441.00
259_F265_G3.6531.00
169_R224_E3.5351.00
229_V250_I3.4961.00
173_V231_A3.3211.00
62_F72_S3.2661.00
27_C138_Q3.1681.00
171_V221_L2.7201.00
229_V274_L2.6221.00
174_V183_Q2.5971.00
191_K278_V2.5401.00
4_A29_L2.4171.00
52_W60_V2.3831.00
184_E187_M2.2541.00
10_Q32_W2.2331.00
246_F264_V2.1971.00
208_V212_K2.1561.00
198_Y208_V2.1541.00
187_M278_V2.1401.00
238_M261_Q2.0941.00
153_S156_D2.0891.00
249_A262_A2.0701.00
10_Q34_I2.0281.00
199_S231_A2.0211.00
170_R194_A1.9881.00
10_Q37_Q1.9751.00
182_N271_K1.9691.00
174_V185_I1.9651.00
186_A196_V1.9461.00
97_V106_L1.9441.00
87_V119_L1.9041.00
229_V270_W1.8971.00
188_L278_V1.8961.00
89_S97_V1.8581.00
225_V248_V1.8471.00
11_E32_W1.8311.00
173_V228_V1.8181.00
178_G185_I1.8031.00
164_P167_E1.7761.00
224_E245_K1.7751.00
132_T135_S1.7701.00
45_L78_R1.7631.00
226_C237_L1.7531.00
185_I229_V1.7401.00
13_A17_S1.7231.00
188_L274_L1.7201.00
249_A258_V1.7131.00
173_V214_I1.6991.00
4_A26_G1.6981.00
49_V78_R1.6971.00
20_A137_M1.6941.00
276_A279_T1.6881.00
188_L192_L1.6881.00
36_P47_A1.6651.00
49_V75_L1.6641.00
61_L119_L1.6591.00
221_L241_V1.6491.00
172_L188_L1.5921.00
165_L171_V1.5721.00
171_V197_G1.5641.00
14_A17_S1.5361.00
4_A57_A1.5331.00
72_S120_S1.5291.00
241_V244_S1.5221.00
40_V43_Q1.4911.00
209_D212_K1.4711.00
41_A70_E1.4641.00
50_E54_R1.4561.00
183_Q196_V1.4411.00
198_Y202_R1.4341.00
20_A28_T1.4091.00
186_A190_E1.4041.00
7_T15_I1.3881.00
187_M191_K1.3551.00
178_G182_N1.3431.00
21_A131_A1.3391.00
162_R190_E1.3361.00
191_K281_I1.3271.00
44_V71_L1.3231.00
20_A135_S1.3201.00
91_D97_V1.3201.00
75_L118_C1.3141.00
228_V231_A1.3091.00
178_G270_W1.3051.00
18_W21_A1.3001.00
13_A139_Q1.2941.00
228_V237_L1.2861.00
34_I37_Q1.2821.00
48_L75_L1.2801.00
197_G214_I1.2781.00
276_A280_N1.2671.00
84_I112_T1.2641.00
31_H47_A1.2581.00
198_Y203_V1.2531.00
33_Q36_P1.2521.00
266_V273_V1.2381.00
88_T97_V1.2351.00
180_A184_E1.2311.00
272_V276_A1.2291.00
38_P154_T1.2251.00
58_D116_P1.2191.00
16_A20_A1.2141.00
86_Q122_A1.2141.00
17_S21_A1.2121.00
87_V121_L1.1931.00
173_V221_L1.1901.00
174_V202_R1.1891.00
88_T106_L1.1611.00
166_A219_H1.1571.00
48_L71_L1.1571.00
100_S105_A1.1481.00
23_D130_N1.1370.99
21_A132_T1.1310.99
181_D184_E1.1290.99
46_D146_A1.1230.99
4_A27_C1.1190.99
39_V44_V1.1150.99
183_Q202_R1.1100.99
29_L140_L1.1100.99
45_L75_L1.1010.99
173_V199_S1.1000.99
13_A32_W1.0990.99
259_F267_V1.0920.99
18_W131_A1.0840.99
8_I44_V1.0840.99
29_L55_T1.0800.99
270_W275_E1.0670.99
268_D272_V1.0660.99
165_L197_G1.0600.99
151_L154_T1.0590.99
177_G207_G1.0570.99
274_L278_V1.0470.99
12_N30_A1.0470.99
203_V213_V1.0410.99
199_S214_I1.0400.99
190_E193_G1.0230.99
179_E271_K1.0230.99
79_L118_C1.0170.99
174_V178_G1.0140.99
91_D109_T1.0120.99
8_I47_A1.0120.99
180_A208_V1.0110.99
45_L74_R1.0080.99
201_A205_N1.0030.99
72_S83_S1.0020.99
5_I19_L1.0020.99
173_V197_G0.9960.99
250_I273_V0.9950.99
15_I18_W0.9850.99
84_I87_V0.9830.98
49_V79_L0.9770.98
222_A243_N0.9740.98
214_I228_V0.9680.98
189_A196_V0.9650.98
174_V208_V0.9640.98
52_W79_L0.9640.98
26_G135_S0.9630.98
180_A207_G0.9630.98
123_R220_L0.9550.98
22_Q131_A0.9540.98
51_Q140_L0.9540.98
195_E212_K0.9540.98
94_T111_Q0.9470.98
12_N32_W0.9470.98
202_R207_G0.9450.98
29_L51_Q0.9440.98
202_R208_V0.9400.98
81_G118_C0.9390.98
165_L219_H0.9290.98
185_I196_V0.9240.98
74_R78_R0.9220.98
46_D50_E0.9180.98
83_S120_S0.9170.98
6_V48_L0.9150.98
83_S118_C0.9140.98
183_Q208_V0.9130.98
9_N12_N0.9040.97
76_A83_S0.8950.97
96_S119_L0.8930.97
69_D86_Q0.8920.97
227_I250_I0.8770.97
20_A132_T0.8720.97
12_N15_I0.8680.97
82_A114_K0.8550.96
46_D143_V0.8540.96
90_L96_S0.8430.96
6_V51_Q0.8350.96
62_F120_S0.8350.96
64_P86_Q0.8340.96
22_Q129_K0.8320.96
35_E144_P0.8320.96
197_G212_K0.8320.96
136_G139_Q0.8300.96
8_I36_P0.8300.96
87_V90_L0.8270.96
54_R138_Q0.8250.96
30_A139_Q0.8250.96
177_G182_N0.8180.95
178_G271_K0.8160.95
64_P68_G0.8090.95
177_G180_A0.8070.95
5_I25_S0.8060.95
187_M196_V0.7980.95
13_A30_A0.7890.94
87_V96_S0.7890.94
52_W116_P0.7850.94
99_K122_A0.7830.94
58_D115_R0.7810.94
39_V70_E0.7800.94
223_P244_S0.7780.94
17_S20_A0.7730.94
94_T117_L0.7730.94
39_V71_L0.7710.94
41_A74_R0.7690.94
96_S117_L0.7670.93
178_G183_Q0.7630.93
62_F68_G0.7630.93
241_V261_Q0.7610.93
204_M213_V0.7560.93
108_A112_T0.7560.93
16_A28_T0.7500.93
9_N32_W0.7470.93
16_A139_Q0.7400.92
178_G207_G0.7380.92
43_Q147_L0.7370.92
21_A134_P0.7340.92
20_A25_S0.7300.92
199_S238_M0.7300.92
137_M140_L0.7290.92
7_T28_T0.7270.92
21_A130_N0.7240.91
23_D132_T0.7200.91
35_E147_L0.7190.91
18_W22_Q0.7180.91
82_A112_T0.7180.91
44_V67_F0.7170.91
42_E148_P0.7160.91
50_E143_V0.7140.91
19_L22_Q0.7130.91
68_G71_L0.7120.91
171_V195_E0.7110.91
21_A133_L0.7110.91
132_T137_M0.7080.90
109_T112_T0.7080.90
176_Q201_A0.7040.90
79_L116_P0.7010.90
72_S75_L0.6990.90
228_V258_V0.6940.90
227_I248_V0.6940.90
258_V265_G0.6920.89
102_W122_A0.6870.89
97_V109_T0.6860.89
143_V146_A0.6770.88
45_L49_V0.6720.88
83_S87_V0.6680.88
5_I8_I0.6670.88
28_T135_S0.6670.88
48_L52_W0.6630.87
214_I241_V0.6600.87
174_V198_Y0.6600.87
52_W57_A0.6600.87
183_Q198_Y0.6560.87
170_R193_G0.6540.87
269_D272_V0.6530.87
40_V151_L0.6530.87
182_N187_M0.6520.86
27_C136_G0.6520.86
95_V109_T0.6520.86
50_E141_N0.6500.86
246_F263_D0.6470.86
173_V237_L0.6450.86
8_I48_L0.6450.86
19_L28_T0.6410.86
43_Q46_D0.6410.86
238_M260_S0.6400.85
273_V276_A0.6360.85
238_M241_V0.6360.85
179_E182_N0.6320.85
47_A50_E0.6320.85
226_C231_A0.6320.85
122_A216_I0.6300.85
14_A18_W0.6280.84
87_V92_I0.6250.84
200_R213_V0.6240.84
56_P116_P0.6220.84
180_A186_A0.6220.84
217_S235_A0.6200.84
74_R77_W0.6200.84
21_A135_S0.6180.83
174_V229_V0.6170.83
199_S228_V0.6170.83
163_D195_E0.6160.83
7_T12_N0.6150.83
135_S214_I0.6140.83
182_N186_A0.6130.83
92_I111_Q0.6130.83
177_G199_S0.6090.83
38_P151_L0.6080.82
191_K194_A0.6070.82
178_G274_L0.6060.82
62_F75_L0.6050.82
112_T117_L0.6050.82
96_S121_L0.6040.82
20_A134_P0.6040.82
221_L244_S0.6040.82
164_P219_H0.6030.82
39_V67_F0.6010.82
92_I95_V0.5990.82
158_K254_A0.5970.81
257_A260_S0.5960.81
172_L196_V0.5960.81
183_Q216_I0.5960.81
178_G202_R0.5930.81
142_I147_L0.5920.81
60_V116_P0.5900.81
98_R236_A0.5900.81
112_T115_R0.5880.80
271_K275_E0.5870.80
188_L191_K0.5870.80
43_Q145_G0.5870.80
144_P147_L0.5850.80
84_I96_S0.5840.80
192_L227_I0.5840.80
162_R186_A0.5830.80
25_S28_T0.5820.80
199_S239_A0.5810.80
172_L191_K0.5780.79
172_L274_L0.5780.79
36_P43_Q0.5770.79
31_H51_Q0.5760.79
249_A259_F0.5760.79
173_V226_C0.5740.79
264_V271_K0.5720.78
172_L278_V0.5720.78
170_R192_L0.5710.78
31_H50_E0.5710.78
62_F71_L0.5710.78
60_V118_C0.5700.78
52_W118_C0.5690.78
81_G114_K0.5680.78
69_D85_C0.5670.78
156_D159_N0.5660.78
51_Q55_T0.5650.78
46_D147_L0.5630.77
127_A130_N0.5610.77
177_G270_W0.5590.77
247_V261_Q0.5580.77
170_R224_E0.5560.77
204_M210_A0.5540.76
254_A257_A0.5540.76
7_T16_A0.5520.76
59_V117_L0.5510.76
198_Y213_V0.5510.76
142_I145_G0.5490.76
274_L281_I0.5460.75
196_V212_K0.5460.75
174_V196_V0.5460.75
80_H114_K0.5440.75
204_M217_S0.5440.75
16_A137_M0.5440.75
185_I214_I0.5430.75
186_A212_K0.5420.75
184_E272_V0.5410.75
249_A265_G0.5410.75
54_R140_L0.5400.74
85_C121_L0.5400.74
145_G148_P0.5360.74
95_V111_Q0.5340.74
154_T157_L0.5330.74
67_F71_L0.5330.74
46_D71_L0.5330.74
84_I194_A0.5310.73
253_D256_A0.5310.73
106_L109_T0.5300.73
171_V214_I0.5290.73
177_G267_V0.5290.73
29_L138_Q0.5260.73
35_E142_I0.5240.72
67_F194_A0.5230.72
235_A263_D0.5230.72
162_R165_L0.5210.72
13_A16_A0.5190.72
133_L136_G0.5170.71
76_A118_C0.5160.71
67_F70_E0.5160.71
210_A214_I0.5140.71
241_V258_V0.5140.71
165_L168_A0.5140.71
244_S247_V0.5130.71
22_Q130_N0.5130.71
90_L109_T0.5120.71
173_V241_V0.5110.70
14_A141_N0.5110.70
221_L261_Q0.5110.70
187_M279_T0.5100.70
91_D94_T0.5100.70
202_R270_W0.5090.70
8_I31_H0.5090.70
91_D95_V0.5050.70
211_E222_A0.5050.70
231_A237_L0.5050.70
258_V264_V0.5050.70
186_A194_A0.5040.69
271_K274_L0.5030.69
32_W139_Q0.5020.69
170_R225_V0.5020.69
12_N37_Q0.5020.69
179_E188_L0.5000.69
170_R227_I0.5000.69
242_R260_S0.5000.69
95_V108_A0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4l2iA 1 0.9895 100 0.06 Contact Map
1efvA 1 0.9755 100 0.068 Contact Map
1efpA 1 0.965 100 0.073 Contact Map
1o97D 1 0.958 100 0.075 Contact Map
3ih5A 6 0.5594 99.9 0.702 Contact Map
1efvB 1 0.6189 99.9 0.747 Contact Map
1efpB 1 0.5979 99.9 0.753 Contact Map
4l2iB 1 0.6434 99.8 0.761 Contact Map
1o97C 1 0.6154 99.8 0.761 Contact Map
3fetA 2 0.4755 99.8 0.769 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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