GREMLIN Database
YGCP - Uncharacterized protein YgcP
UniProt: Q46906 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13123
Length: 191 (179)
Sequences: 642 (520)
Seq/√Len: 38.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
50_I57_A4.0491.00
144_W160_C3.9341.00
162_E166_R3.0391.00
25_A33_I3.0241.00
21_S181_T3.0061.00
67_A73_V2.8281.00
14_A30_C2.7101.00
98_R129_D2.6771.00
33_I50_I2.6001.00
51_K84_D2.5411.00
48_K52_N2.5231.00
94_L104_C2.4481.00
47_V81_T2.4251.00
23_Q49_K2.4151.00
88_S94_L2.3781.00
44_S80_V2.3361.00
140_K164_D2.1800.99
77_L83_A1.9570.99
96_A99_A1.9490.99
24_L181_T1.9280.98
60_H156_G1.8640.98
89_T156_G1.8490.98
18_D21_S1.8310.98
108_L119_I1.8160.98
47_V57_A1.7960.97
122_Q134_L1.7630.97
16_V50_I1.7630.97
76_F80_V1.7550.97
22_L50_I1.7410.97
75_Q96_A1.7250.97
145_V153_L1.6820.96
19_N37_Y1.6420.96
63_L179_T1.6190.95
78_K102_F1.6170.95
43_I76_F1.6100.95
178_T183_V1.5800.95
43_I81_T1.5690.94
146_T153_L1.5650.94
31_Q56_Y1.5620.94
138_M141_V1.5100.93
107_R132_E1.4790.92
154_I177_S1.4610.92
64_L98_R1.4510.92
88_S93_M1.4430.92
120_D145_V1.4350.91
43_I51_K1.4050.90
133_I145_V1.3890.90
79_L131_I1.3500.89
89_T109_F1.3460.88
74_I100_E1.3400.88
64_L67_A1.3140.87
105_I130_C1.3130.87
165_A183_V1.2980.86
17_K63_L1.2900.86
168_A173_V1.2890.86
143_G147_E1.2850.86
35_V50_I1.2800.86
117_H148_K1.2650.85
91_A170_N1.2600.85
60_H89_T1.2570.85
32_F56_Y1.2430.84
107_R156_G1.2390.84
163_E167_N1.2330.83
47_V84_D1.2260.83
15_A36_L1.2180.83
106_H159_V1.2160.83
121_K174_V1.2150.83
35_V57_A1.2070.82
36_L107_R1.1300.78
146_T174_V1.1020.76
37_Y113_S1.1010.76
71_E134_L1.0920.75
61_V74_I1.0900.75
124_A148_K1.0810.74
75_Q100_E1.0680.74
39_N75_Q1.0650.73
46_I58_F1.0650.73
111_V134_L1.0630.73
131_I151_Q1.0530.73
123_V128_P1.0510.72
58_F85_G1.0510.72
110_I140_K1.0470.72
88_S104_C1.0470.72
111_V167_N1.0340.71
97_A104_C1.0300.71
54_G147_E0.9970.68
22_L26_I0.9760.67
32_F87_I0.9670.66
68_S118_N0.9610.65
131_I149_I0.9540.65
14_A134_L0.9530.65
27_D53_A0.9520.65
85_G107_R0.9420.64
124_A176_L0.9390.64
38_G111_V0.9270.63
106_H152_P0.9250.62
60_H128_P0.9210.62
144_W148_K0.9190.62
94_L126_S0.9130.61
27_D182_G0.9100.61
35_V46_I0.9080.61
16_V46_I0.8990.60
20_A182_G0.8990.60
36_L87_I0.8980.60
36_L62_D0.8960.60
19_N179_T0.8920.60
165_A168_A0.8710.58
11_P46_I0.8680.57
142_L155_A0.8670.57
35_V179_T0.8650.57
74_I102_F0.8570.56
84_D108_L0.8540.56
86_I162_E0.8490.56
39_N72_V0.8390.55
11_P162_E0.8350.55
142_L173_V0.8330.54
35_V69_N0.8320.54
68_S93_M0.8290.54
61_V77_L0.8270.54
46_I179_T0.8270.54
87_I134_L0.8260.54
147_E181_T0.8240.54
142_L168_A0.8230.53
118_N121_K0.8200.53
170_N174_V0.8130.53
117_H120_D0.8120.52
86_I167_N0.8010.51
16_V33_I0.7980.51
15_A177_S0.7940.51
18_D25_A0.7930.51
90_K102_F0.7920.51
96_A118_N0.7890.50
74_I86_I0.7860.50
140_K165_A0.7810.50
11_P59_I0.7810.50
161_D166_R0.7810.50
44_S48_K0.7800.50
130_C133_I0.7790.49
49_K53_A0.7780.49
120_D123_V0.7770.49
22_L114_I0.7770.49
119_I130_C0.7760.49
115_S156_G0.7730.49
47_V108_L0.7660.48
28_S171_A0.7650.48
10_N78_K0.7560.47
32_F59_I0.7550.47
127_N151_Q0.7540.47
60_H107_R0.7520.47
152_P169_I0.7420.46
37_Y179_T0.7340.45
136_G142_L0.7310.45
36_L89_T0.7280.45
58_F183_V0.7270.45
78_K83_A0.7240.45
68_S151_Q0.7220.44
67_A75_Q0.7200.44
74_I78_K0.7170.44
35_V110_I0.7170.44
91_A106_H0.7160.44
57_A84_D0.7070.43
38_G119_I0.7040.43
17_K70_K0.7020.43
139_P153_L0.6980.42
14_A56_Y0.6940.42
24_L82_E0.6830.41
15_A111_V0.6820.41
88_S145_V0.6810.41
166_R170_N0.6790.41
71_E88_S0.6710.40
8_R29_E0.6670.40
43_I58_F0.6660.39
58_F180_N0.6650.39
88_S167_N0.6650.39
94_L128_P0.6640.39
17_K164_D0.6610.39
107_R134_L0.6600.39
64_L110_I0.6590.39
22_L49_K0.6580.39
85_G132_E0.6570.39
136_G173_V0.6560.39
40_I154_I0.6540.38
136_G159_V0.6530.38
132_E156_G0.6500.38
58_F154_I0.6490.38
47_V51_K0.6450.38
36_L134_L0.6450.38
16_V19_N0.6430.37
89_T106_H0.6420.37
63_L134_L0.6420.37
116_F145_V0.6410.37
78_K100_E0.6390.37
88_S129_D0.6340.37
90_K173_V0.6320.37
160_C176_L0.6310.36
62_D136_G0.6270.36
15_A171_A0.6230.36
36_L63_L0.6220.36
58_F103_F0.6210.36
40_I93_M0.6200.36
144_W147_E0.6160.35
146_T163_E0.6160.35
95_K141_V0.6120.35
34_S38_G0.6120.35
123_V149_I0.6120.35
141_V164_D0.6090.35
76_F90_K0.5990.34
30_C39_N0.5980.34
155_A164_D0.5960.34
12_V62_D0.5960.34
175_A183_V0.5950.33
61_V103_F0.5940.33
92_S106_H0.5920.33
29_E126_S0.5900.33
33_I69_N0.5890.33
167_N170_N0.5820.32
118_N122_Q0.5780.32
20_A23_Q0.5750.32
27_D54_G0.5750.32
95_K158_L0.5730.32
11_P18_D0.5730.32
73_V130_C0.5690.31
102_F163_E0.5680.31
35_V101_G0.5680.31
19_N170_N0.5670.31
59_I77_L0.5640.31
54_G170_N0.5640.31
28_S55_K0.5630.31
19_N46_I0.5610.31
137_C158_L0.5580.31
38_G158_L0.5570.31
70_K81_T0.5560.30
126_S159_V0.5560.30
28_S101_G0.5550.30
36_L113_S0.5530.30
134_L139_P0.5510.30
9_Q31_Q0.5510.30
49_K101_G0.5490.30
28_S185_T0.5470.30
10_N115_S0.5460.30
51_K170_N0.5460.30
113_S168_A0.5450.30
59_I146_T0.5430.29
138_M183_V0.5430.29
21_S176_L0.5420.29
33_I63_L0.5410.29
17_K114_I0.5410.29
134_L156_G0.5390.29
62_D165_A0.5350.29
10_N30_C0.5350.29
59_I83_A0.5350.29
116_F160_C0.5320.29
75_Q128_P0.5320.29
59_I159_V0.5240.28
71_E130_C0.5220.28
27_D124_A0.5200.28
26_I55_K0.5200.28
7_L77_L0.5170.28
42_T159_V0.5160.27
83_A173_V0.5140.27
123_V126_S0.5130.27
88_S108_L0.5110.27
74_I84_D0.5110.27
12_V165_A0.5110.27
63_L155_A0.5110.27
44_S150_R0.5070.27
78_K88_S0.5050.27
36_L178_T0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1vkfA 1 0.8953 100 0.192 Contact Map
3ktsA 1 0.9686 100 0.36 Contact Map
1wa3A 3 0.9267 98.9 0.832 Contact Map
4adtA 5 0.9319 98.6 0.849 Contact Map
3vcrA 3 0.9267 98.6 0.851 Contact Map
1vhcA 3 0.9267 98.5 0.854 Contact Map
4jejA 2 0.9581 98.4 0.858 Contact Map
3vndA 3 0.9476 98.4 0.858 Contact Map
1rd5A 6 0.9529 98.4 0.859 Contact Map
2yw3A 4 0.9162 98.4 0.859 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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