YGIS - ECOLI - GREMLIN Contacts

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YGIS - Putative binding protein YgiS

UniProt:	Q46863	Sequences: MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPGTLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQWSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKATDDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDQWVVNEKITARKNPKYRDAQHTVLQQVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIEKSLPGELRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATTLTPPEVKGFSATTFDELQKPMSERVAMAKALLKQAGYDASHPLRFELFYNKYDLHEKTAIALSSEWKKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASSFLNTLKSDSEENVGHWKNAQYDALLNQATQITDATKRNALYQQAEVIINQQAPLIPIYYQPLIKLLKPYVGGFPLHNPQDYVYSKELYIKAH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13021
Length:	535 (487)
Sequences:	23039 (17506)
Seq/√Len:	793.3

ECOLI - YGIS OPPA MPPA DPPA DDPA SAPA GSIB NIKA YEJA YBAE SGRR
BACSU - OPPA DPPE APPA YHJP
HALSA - Q9HMW4 Q9HMI3
SULSO - Q97VK5 Q97VF7 Q97UG7 Q97UH5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
215_D	226_R	4.171	1.00
158_K	166_E	3.243	1.00
307_R	368_Q	3.225	1.00
160_T	166_E	3.187	1.00
361_M	364_A	3.114	1.00
99_S	163_R	3.081	1.00
319_Q	323_Q	2.940	1.00
161_D	164_T	2.902	1.00
115_V	119_Q	2.899	1.00
466_A	470_Q	2.898	1.00
213_V	226_R	2.778	1.00
474_I	479_K	2.755	1.00
301_P	304_N	2.660	1.00
115_V	159_A	2.588	1.00
314_L	361_M	2.527	1.00
378_R	407_Q	2.505	1.00
317_D	320_L	2.481	1.00
364_A	368_Q	2.470	1.00
378_R	409_T	2.455	1.00
83_R	96_H	2.447	1.00
312_L	400_W	2.407	1.00
190_H	194_A	2.395	1.00
34_V	241_Q	2.368	1.00
85_E	96_H	2.355	1.00
112_E	159_A	2.308	1.00
463_Q	466_A	2.307	1.00
158_K	168_T	2.301	1.00
92_R	166_E	2.284	1.00
109_L	209_N	2.281	1.00
71_D	75_Q	2.263	1.00
380_E	411_R	2.258	1.00
459_W	494_Q	2.232	1.00
306_V	310_R	2.202	1.00
68_V	84_W	2.195	1.00
94_I	166_E	2.193	1.00
107_Q	191_H	2.176	1.00
401_K	407_Q	2.164	1.00
479_K	482_A	2.159	1.00
307_R	310_R	2.149	1.00
87_L	91_K	2.148	1.00
104_S	228_N	2.131	1.00
307_R	365_L	2.125	1.00
102_Q	108_P	2.123	1.00
224_T	241_Q	2.084	1.00
461_N	490_I	2.068	1.00
92_R	168_T	2.059	1.00
71_D	77_Q	2.028	1.00
470_Q	483_L	2.022	1.00
155_L	170_E	2.020	1.00
102_Q	230_K	2.019	1.00
461_N	494_Q	2.018	1.00
86_I	93_Y	2.014	1.00
380_E	409_T	1.995	1.00
476_D	479_K	1.986	1.00
300_K	428_M	1.975	1.00
65_E	79_A	1.973	1.00
101_L	109_L	1.963	1.00
34_V	243_E	1.928	1.00
112_E	190_H	1.920	1.00
482_A	486_Q	1.909	1.00
96_H	164_T	1.903	1.00
256_R	261_E	1.889	1.00
376_P	407_Q	1.866	1.00
82_E	99_S	1.821	1.00
47_D	120_R	1.819	1.00
118_W	167_V	1.818	1.00
38_N	262_V	1.814	1.00
464_Y	487_A	1.806	1.00
213_V	229_P	1.801	1.00
218_V	221_E	1.789	1.00
114_F	165_L	1.779	1.00
397_S	401_K	1.777	1.00
216_Q	224_T	1.763	1.00
463_Q	486_Q	1.761	1.00
296_F	498_I	1.759	1.00
110_T	113_D	1.747	1.00
113_D	190_H	1.745	1.00
471_A	484_Y	1.734	1.00
306_V	494_Q	1.733	1.00
226_R	241_Q	1.732	1.00
216_Q	222_K	1.731	1.00
36_R	243_E	1.727	1.00
467_L	486_Q	1.705	1.00
315_T	404_L	1.699	1.00
463_Q	490_I	1.679	1.00
489_V	493_Q	1.678	1.00
450_S	460_K	1.677	1.00
450_S	465_D	1.674	1.00
421_A	426_D	1.671	1.00
82_E	96_H	1.661	1.00
332_A	502_Y	1.660	1.00
156_G	168_T	1.650	1.00
100_G	108_P	1.650	1.00
215_D	241_Q	1.629	1.00
471_A	483_L	1.624	1.00
222_K	243_E	1.610	1.00
112_E	162_D	1.610	1.00
462_A	466_A	1.608	1.00
33_Q	240_Q	1.596	1.00
227_K	240_Q	1.592	1.00
310_R	361_M	1.592	1.00
105_D	189_P	1.578	1.00
296_F	429_L	1.575	1.00
420_D	424_A	1.568	1.00
112_E	115_V	1.559	1.00
273_P	276_E	1.557	1.00
358_R	361_M	1.551	1.00
258_R	274_A	1.536	1.00
486_Q	489_V	1.536	1.00
82_E	98_R	1.530	1.00
218_V	222_K	1.528	1.00
319_Q	331_P	1.526	1.00
110_T	162_D	1.523	1.00
467_L	483_L	1.519	1.00
451_D	460_K	1.519	1.00
107_Q	189_P	1.513	1.00
87_L	92_R	1.504	1.00
316_V	396_L	1.497	1.00
68_V	95_F	1.489	1.00
414_E	417_T	1.474	1.00
310_R	495_A	1.469	1.00
460_K	465_D	1.468	1.00
111_A	159_A	1.459	1.00
299_E	458_H	1.442	1.00
212_F	239_L	1.440	1.00
483_L	486_Q	1.430	1.00
390_E	394_I	1.429	1.00
247_L	256_R	1.428	1.00
65_E	232_R	1.402	1.00
474_I	483_L	1.398	1.00
313_Y	495_A	1.395	1.00
94_I	164_T	1.395	1.00
224_T	243_E	1.394	1.00
87_L	94_I	1.391	1.00
481_N	485_Q	1.391	1.00
280_P	511_P	1.387	1.00
360_A	363_K	1.384	1.00
363_K	367_K	1.383	1.00
84_W	95_F	1.379	1.00
306_V	493_Q	1.373	1.00
53_E	56_A	1.361	1.00
344_S	347_T	1.361	1.00
102_Q	228_N	1.342	1.00
470_Q	479_K	1.329	1.00
411_R	421_A	1.329	1.00
322_A	331_P	1.328	1.00
312_L	406_A	1.322	1.00
482_A	485_Q	1.319	1.00
490_I	494_Q	1.315	1.00
65_E	209_N	1.315	1.00
104_S	213_V	1.297	1.00
300_K	304_N	1.294	1.00
399_E	402_K	1.291	1.00
466_A	469_N	1.291	1.00
479_K	483_L	1.284	1.00
160_T	164_T	1.283	1.00
451_D	465_D	1.282	1.00
115_V	157_V	1.279	1.00
36_R	245_L	1.277	1.00
189_P	192_V	1.275	1.00
96_H	163_R	1.272	1.00
36_R	263_D	1.268	1.00
108_P	163_R	1.261	1.00
308_V	366_L	1.259	1.00
282_E	511_P	1.257	1.00
449_K	469_N	1.255	1.00
467_L	490_I	1.250	1.00
155_L	168_T	1.249	1.00
159_A	162_D	1.249	1.00
167_V	176_F	1.247	1.00
35_F	264_L	1.242	1.00
101_L	209_N	1.235	1.00
215_D	224_T	1.231	1.00
38_N	253_G	1.227	1.00
303_F	312_L	1.220	1.00
109_L	187_P	1.210	1.00
105_D	191_H	1.208	1.00
440_D	480_R	1.206	1.00
256_R	262_V	1.206	1.00
257_Y	508_L	1.196	1.00
295_N	430_S	1.194	1.00
395_A	399_E	1.192	1.00
171_Q	473_Q	1.192	1.00
398_S	402_K	1.189	1.00
383_Y	410_L	1.186	1.00
225_A	244_Y	1.183	1.00
463_Q	467_L	1.176	1.00
338_P	502_Y	1.174	1.00
459_W	464_Y	1.173	1.00
365_L	368_Q	1.172	1.00
98_R	101_L	1.172	1.00
119_Q	123_D	1.171	1.00
258_R	278_S	1.168	1.00
364_A	367_K	1.163	1.00
478_T	481_N	1.160	1.00
322_A	329_R	1.153	1.00
470_Q	474_I	1.152	1.00
383_Y	412_T	1.151	1.00
78_P	84_W	1.151	1.00
222_K	245_L	1.151	1.00
263_D	512_Y	1.147	1.00
69_W	77_Q	1.142	1.00
308_V	369_A	1.141	1.00
85_E	94_I	1.135	1.00
80_Q	209_N	1.135	1.00
98_R	232_R	1.134	1.00
303_F	379_F	1.130	1.00
93_Y	176_F	1.130	1.00
104_S	230_K	1.129	1.00
397_S	410_L	1.128	1.00
359_V	363_K	1.126	1.00
320_L	399_E	1.121	1.00
69_W	79_A	1.121	1.00
263_D	510_K	1.115	1.00
415_W	419_L	1.112	1.00
117_G	187_P	1.112	1.00
13_V	16_A	1.109	1.00
157_V	165_L	1.107	1.00
425_G	458_H	1.104	1.00
273_P	277_K	1.104	1.00
400_W	408_V	1.101	1.00
32_Q	240_Q	1.100	1.00
213_V	228_N	1.095	1.00
326_L	501_Y	1.079	1.00
14_S	17_P	1.079	1.00
306_V	495_A	1.077	1.00
284_R	509_L	1.075	1.00
285_I	504_P	1.072	1.00
367_K	372_D	1.072	1.00
478_T	482_A	1.071	1.00
114_F	187_P	1.071	1.00
310_R	365_L	1.068	1.00
227_K	237_T	1.066	1.00
18_L	21_A	1.065	1.00
379_F	408_V	1.064	1.00
59_I	225_A	1.059	1.00
108_P	162_D	1.058	1.00
490_I	493_Q	1.057	1.00
470_Q	486_Q	1.057	1.00
282_E	509_L	1.053	1.00
360_A	364_A	1.050	1.00
315_T	400_W	1.047	1.00
191_H	195_K	1.043	1.00
467_L	487_A	1.041	1.00
95_F	167_V	1.035	1.00
467_L	470_Q	1.033	1.00
104_S	207_V	1.031	1.00
116_L	190_H	1.029	1.00
80_Q	101_L	1.027	1.00
381_L	408_V	1.026	1.00
192_V	207_V	1.024	1.00
397_S	408_V	1.022	1.00
359_V	404_L	1.020	1.00
330_T	504_P	1.012	1.00
82_E	163_R	1.006	1.00
252_T	256_R	0.991	1.00
398_S	401_K	0.990	1.00
35_F	239_L	0.986	1.00
111_A	160_T	0.985	1.00
296_F	312_L	0.983	1.00
396_L	400_W	0.979	1.00
307_R	369_A	0.979	1.00
119_Q	122_V	0.977	1.00
313_Y	318_R	0.976	1.00
96_H	99_S	0.971	1.00
344_S	485_Q	0.971	1.00
272_I	276_E	0.970	1.00
113_D	116_L	0.969	1.00
469_N	473_Q	0.969	1.00
226_R	229_P	0.968	1.00
417_T	421_A	0.967	1.00
393_A	410_L	0.959	1.00
80_Q	114_F	0.958	1.00
464_Y	468_L	0.954	1.00
93_Y	177_T	0.953	1.00
471_A	487_A	0.952	1.00
464_Y	491_I	0.951	1.00
21_A	24_P	0.948	1.00
103_W	113_D	0.945	1.00
320_L	324_K	0.945	1.00
321_I	392_T	0.943	1.00
42_D	217_W	0.942	1.00
111_A	165_L	0.940	1.00
310_R	314_L	0.940	1.00
459_W	496_P	0.938	1.00
323_Q	327_G	0.938	1.00
262_V	265_T	0.937	1.00
361_M	365_L	0.934	1.00
255_N	258_R	0.933	1.00
314_L	355_M	0.931	1.00
176_F	180_L	0.930	1.00
94_I	160_T	0.929	1.00
276_E	285_I	0.924	1.00
112_E	116_L	0.924	1.00
227_K	234_A	0.922	1.00
93_Y	169_L	0.922	1.00
66_G	79_A	0.921	1.00
96_H	161_D	0.917	1.00
99_S	108_P	0.916	1.00
310_R	493_Q	0.913	1.00
275_I	281_G	0.911	1.00
379_F	429_L	0.909	1.00
65_E	231_Y	0.909	1.00
413_M	421_A	0.908	1.00
271_Q	274_A	0.907	1.00
391_K	394_I	0.904	1.00
326_L	329_R	0.903	1.00
63_L	225_A	0.903	1.00
330_T	338_P	0.902	1.00
68_V	177_T	0.902	1.00
116_L	193_I	0.901	1.00
68_V	81_A	0.897	1.00
173_V	179_M	0.896	1.00
81_A	95_F	0.896	1.00
359_V	402_K	0.896	1.00
322_A	501_Y	0.895	1.00
313_Y	498_I	0.893	1.00
35_F	513_V	0.892	1.00
281_G	508_L	0.892	1.00
344_S	489_V	0.891	1.00
477_A	481_N	0.891	1.00
254_Y	258_R	0.889	1.00
104_S	208_Y	0.885	1.00
464_Y	490_I	0.884	1.00
104_S	214_L	0.882	1.00
153_T	173_V	0.876	1.00
68_V	76_V	0.875	1.00
257_Y	281_G	0.869	1.00
169_L	176_F	0.867	1.00
422_R	430_S	0.865	1.00
487_A	490_I	0.864	1.00
317_D	399_E	0.864	1.00
295_N	457_G	0.852	1.00
115_V	165_L	0.850	1.00
372_D	375_H	0.847	1.00
159_A	165_L	0.846	1.00
227_K	235_Q	0.845	1.00
357_E	402_K	0.840	1.00
470_Q	473_Q	0.839	1.00
247_L	262_V	0.836	1.00
119_Q	157_V	0.834	1.00
105_D	207_V	0.832	1.00
362_A	404_L	0.828	1.00
87_L	90_G	0.827	1.00
254_Y	275_I	0.824	1.00
88_D	92_R	0.824	1.00
268_P	271_Q	0.823	1.00
257_Y	265_T	0.823	1.00
31_P	238_V	0.823	1.00
95_F	177_T	0.823	1.00
17_P	20_A	0.820	1.00
101_L	163_R	0.820	1.00
485_Q	489_V	0.817	1.00
318_R	331_P	0.815	1.00
217_W	223_I	0.815	1.00
468_L	487_A	0.812	1.00
66_G	186_F	0.811	1.00
335_L	499_P	0.810	1.00
382_F	421_A	0.809	1.00
91_K	155_L	0.807	1.00
14_S	18_L	0.805	1.00
16_A	19_Y	0.804	1.00
91_K	168_T	0.801	1.00
63_L	214_L	0.800	1.00
80_Q	109_L	0.796	1.00
314_L	365_L	0.796	1.00
486_Q	490_I	0.796	1.00
442_S	472_T	0.790	1.00
311_A	366_L	0.789	1.00
227_K	239_L	0.786	1.00
212_F	237_T	0.783	1.00
290_N	435_D	0.782	1.00
15_A	18_L	0.781	1.00
294_Y	396_L	0.777	1.00
64_F	208_Y	0.775	1.00
315_T	359_V	0.769	1.00
21_A	25_A	0.768	1.00
37_Y	264_L	0.768	1.00
100_G	163_R	0.767	1.00
255_N	259_A	0.766	1.00
30_A	33_Q	0.766	1.00
42_D	246_A	0.765	1.00
62_D	225_A	0.763	1.00
72_G	517_P	0.763	1.00
214_L	223_I	0.761	1.00
371_Y	374_S	0.760	1.00
294_Y	429_L	0.760	1.00
317_D	357_E	0.758	1.00
305_D	371_Y	0.758	1.00
462_A	465_D	0.758	1.00
253_G	265_T	0.756	1.00
455_N	458_H	0.755	1.00
91_K	171_Q	0.755	1.00
9_L	12_L	0.753	1.00
175_W	440_D	0.753	1.00
299_E	425_G	0.752	1.00
113_D	117_G	0.752	1.00
153_T	171_Q	0.751	1.00
287_P	504_P	0.750	1.00
95_F	180_L	0.749	1.00
382_F	413_M	0.749	1.00
285_I	328_L	0.748	1.00
101_L	232_R	0.747	1.00
305_D	369_A	0.746	1.00
49_Q	120_R	0.746	1.00
316_V	321_I	0.746	1.00
383_Y	393_A	0.745	1.00
394_I	410_L	0.744	1.00
10_V	16_A	0.742	1.00
275_I	508_L	0.742	1.00
278_S	281_G	0.742	1.00
123_D	126_T	0.742	1.00
298_L	496_P	0.742	1.00
79_A	232_R	0.740	1.00
159_A	166_E	0.739	1.00
401_K	406_A	0.737	1.00
154_S	157_V	0.734	1.00
314_L	357_E	0.733	1.00
97_L	109_L	0.733	1.00
285_I	506_I	0.731	1.00
229_P	240_Q	0.731	1.00
380_E	428_M	0.731	1.00
365_L	369_A	0.729	1.00
33_Q	239_L	0.727	1.00
390_E	412_T	0.722	1.00
29_L	238_V	0.719	1.00
10_V	13_V	0.718	1.00
225_A	242_V	0.716	1.00
86_I	90_G	0.715	1.00
308_V	371_Y	0.715	1.00
459_W	490_I	0.713	1.00
371_Y	375_H	0.713	1.00
292_E	389_H	0.712	1.00
316_V	400_W	0.711	1.00
279_L	511_P	0.711	1.00
226_R	240_Q	0.710	1.00
445_L	449_K	0.708	1.00
417_T	420_D	0.707	1.00
400_W	429_L	0.705	1.00
264_L	513_V	0.705	1.00
84_W	177_T	0.703	1.00
381_L	393_A	0.701	1.00
413_M	417_T	0.701	1.00
312_L	429_L	0.700	1.00
35_F	242_V	0.700	1.00
321_I	395_A	0.698	1.00
300_K	303_F	0.696	1.00
312_L	498_I	0.696	1.00
296_F	303_F	0.694	1.00
366_L	404_L	0.691	1.00
63_L	208_Y	0.690	1.00
401_K	408_V	0.689	1.00
247_L	253_G	0.688	1.00
442_S	446_N	0.688	1.00
334_T	488_E	0.687	1.00
116_L	194_A	0.687	1.00
117_G	188_V	0.687	1.00
366_L	371_Y	0.686	1.00
157_V	167_V	0.684	1.00
192_V	196_H	0.684	1.00
111_A	115_V	0.683	1.00
394_I	397_S	0.683	1.00
449_K	468_L	0.682	1.00
62_D	242_V	0.682	1.00
400_W	404_L	0.681	1.00
377_L	406_A	0.680	1.00
59_I	223_I	0.680	1.00
480_R	484_Y	0.679	1.00
67_L	81_A	0.679	1.00
366_L	369_A	0.679	1.00
383_Y	390_E	0.679	1.00
437_T	443_S	0.677	1.00
343_F	347_T	0.677	1.00
17_P	21_A	0.676	1.00
418_Y	430_S	0.676	1.00
341_K	477_A	0.676	1.00
49_Q	121_A	0.675	1.00
450_S	469_N	0.674	1.00
245_L	256_R	0.674	1.00
381_L	431_R	0.673	1.00
386_Y	390_E	0.673	1.00
132_G	135_A	0.672	1.00
85_E	88_D	0.672	1.00
191_H	194_A	0.672	1.00
38_N	247_L	0.671	1.00
371_Y	377_L	0.670	1.00
394_I	398_S	0.669	1.00
70_M	76_V	0.668	1.00
314_L	356_S	0.667	1.00
103_W	187_P	0.666	1.00
97_L	163_R	0.666	1.00
51_V	60_V	0.665	1.00
342_G	481_N	0.664	1.00
298_L	457_G	0.663	1.00
64_F	206_M	0.662	1.00
48_P	188_V	0.662	1.00
442_S	484_Y	0.660	1.00
42_D	219_V	0.659	1.00
496_P	499_P	0.656	1.00
280_P	510_K	0.655	1.00
374_S	377_L	0.654	1.00
483_L	487_A	0.653	1.00
109_L	163_R	0.650	1.00
312_L	379_F	0.649	1.00
153_T	170_E	0.648	1.00
313_Y	355_M	0.646	1.00
103_W	109_L	0.645	1.00
213_V	230_K	0.643	1.00
122_V	170_E	0.643	1.00
382_F	411_R	0.643	1.00
305_D	308_V	0.640	1.00
315_T	357_E	0.640	1.00
189_P	207_V	0.640	1.00
86_I	177_T	0.639	1.00
214_L	217_W	0.638	1.00
21_A	26_N	0.638	1.00
103_W	208_Y	0.637	1.00
115_V	158_K	0.637	1.00
12_L	15_A	0.635	1.00
396_L	408_V	0.633	1.00
89_G	92_R	0.633	1.00
303_F	308_V	0.632	1.00
11_S	15_A	0.632	1.00
70_M	181_A	0.631	1.00
239_L	513_V	0.631	1.00
305_D	370_G	0.630	1.00
33_Q	238_V	0.630	1.00
174_P	480_R	0.629	1.00
400_W	406_A	0.628	1.00
321_I	396_L	0.627	1.00
509_L	516_F	0.627	1.00
415_W	432_Q	0.623	1.00
196_H	199_S	0.623	1.00
32_Q	238_V	0.621	1.00
118_W	180_L	0.621	1.00
44_G	53_E	0.619	1.00
105_D	192_V	0.619	1.00
469_N	472_T	0.619	1.00
257_Y	510_K	0.619	1.00
477_A	480_R	0.618	1.00
384_N	389_H	0.617	1.00
107_Q	113_D	0.617	1.00
223_I	246_A	0.616	1.00
446_N	450_S	0.615	1.00
510_K	513_V	0.615	1.00
110_T	163_R	0.615	1.00
366_L	406_A	0.613	1.00
116_L	120_R	0.613	1.00
91_K	172_P	0.612	1.00
319_Q	322_A	0.611	1.00
13_V	17_P	0.610	1.00
111_A	161_D	0.609	1.00
44_G	56_A	0.608	1.00
64_F	209_N	0.607	1.00
111_A	163_R	0.606	1.00
11_S	14_S	0.606	1.00
465_D	469_N	0.605	1.00
328_L	506_I	0.605	1.00
119_Q	156_G	0.604	1.00
292_E	392_T	0.602	1.00
103_W	191_H	0.600	1.00
171_Q	469_N	0.599	1.00
119_Q	190_H	0.599	1.00
8_W	11_S	0.598	1.00
84_W	96_H	0.598	1.00
274_A	278_S	0.598	1.00
249_N	252_T	0.598	1.00
267_V	508_L	0.597	1.00
392_T	396_L	0.597	1.00
299_E	304_N	0.594	1.00
212_F	241_Q	0.594	1.00
282_E	514_G	0.594	1.00
363_K	404_L	0.594	1.00
298_L	304_N	0.593	1.00
344_S	488_E	0.592	1.00
110_T	190_H	0.590	1.00
343_F	346_T	0.590	1.00
291_S	332_A	0.587	1.00
382_F	427_F	0.587	1.00
109_L	117_G	0.585	1.00
212_F	227_K	0.585	1.00
66_G	209_N	0.584	1.00
354_P	492_N	0.584	1.00
124_P	127_A	0.583	1.00
9_L	13_V	0.581	1.00
95_F	165_L	0.581	1.00
86_I	89_G	0.579	1.00
357_E	399_E	0.576	1.00
76_V	177_T	0.576	1.00
63_L	206_M	0.575	1.00
359_V	366_L	0.575	1.00
293_Y	497_L	0.575	1.00
119_Q	159_A	0.575	1.00
119_Q	153_T	0.574	1.00
71_D	74_G	0.574	1.00
103_W	209_N	0.573	1.00
221_E	245_L	0.573	1.00
316_V	498_I	0.573	1.00
67_L	114_F	0.573	1.00
97_L	101_L	0.573	1.00
371_Y	406_A	0.571	1.00
57_A	183_P	0.570	1.00
413_M	418_Y	0.568	1.00
392_T	501_Y	0.567	1.00
358_R	364_A	0.567	1.00
366_L	370_G	0.567	1.00
196_H	205_N	0.564	1.00
116_L	191_H	0.564	1.00
314_L	362_A	0.564	1.00
384_N	418_Y	0.563	1.00
495_A	498_I	0.563	1.00
245_L	261_E	0.562	1.00
464_Y	467_L	0.561	1.00
250_S	253_G	0.561	1.00
367_K	371_Y	0.560	1.00
328_L	504_P	0.559	1.00
257_Y	262_V	0.559	1.00
234_A	237_T	0.559	1.00
206_M	214_L	0.559	1.00
92_R	158_K	0.559	1.00
28_P	31_P	0.558	1.00
471_A	480_R	0.558	1.00
372_D	376_P	0.558	1.00
29_L	33_Q	0.557	1.00
267_V	272_I	0.556	1.00
46_L	217_W	0.555	1.00
353_K	356_S	0.555	1.00
51_V	56_A	0.555	1.00
12_L	16_A	0.554	1.00
296_F	313_Y	0.554	1.00
461_N	464_Y	0.554	1.00
319_Q	356_S	0.553	1.00
88_D	91_K	0.552	1.00
316_V	500_I	0.551	1.00
19_Y	22_D	0.550	1.00
338_P	343_F	0.550	1.00
233_D	237_T	0.550	1.00
10_V	14_S	0.549	1.00
39_N	244_Y	0.549	1.00
254_Y	271_Q	0.548	1.00
294_Y	500_I	0.548	1.00
29_L	32_Q	0.546	1.00
234_A	238_V	0.545	1.00
346_T	485_Q	0.545	1.00
474_I	480_R	0.544	1.00
53_E	415_W	0.542	1.00
287_P	330_T	0.542	1.00
260_G	510_K	0.541	1.00
308_V	312_L	0.541	1.00
369_A	374_S	0.540	1.00
264_L	509_L	0.539	1.00
9_L	15_A	0.539	1.00
493_Q	496_P	0.539	1.00
154_S	170_E	0.539	1.00
65_E	233_D	0.539	1.00
36_R	262_V	0.539	1.00
387_D	391_K	0.539	1.00
399_E	404_L	0.538	1.00
214_L	225_A	0.538	1.00
308_V	377_L	0.536	1.00
314_L	358_R	0.535	1.00
475_T	479_K	0.534	1.00
448_L	451_D	0.534	1.00
62_D	244_Y	0.534	1.00
46_L	223_I	0.534	1.00
434_W	437_T	0.533	1.00
11_S	17_P	0.533	1.00
467_L	471_A	0.533	1.00
104_S	209_N	0.532	1.00
487_A	491_I	0.532	1.00
408_V	429_L	0.532	1.00
380_E	383_Y	0.531	1.00
328_L	331_P	0.531	1.00
457_G	497_L	0.531	1.00
78_P	83_R	0.531	1.00
154_S	167_V	0.530	1.00
321_I	500_I	0.529	1.00
325_V	395_A	0.529	1.00
251_V	255_N	0.529	1.00
228_N	231_Y	0.528	1.00
131_A	135_A	0.526	1.00
69_W	233_D	0.526	1.00
108_P	113_D	0.524	1.00
300_K	426_D	0.523	1.00
90_G	475_T	0.522	1.00
272_I	283_L	0.521	1.00
82_E	97_L	0.521	1.00
322_A	326_L	0.521	1.00
355_M	495_A	0.521	1.00
22_D	25_A	0.521	1.00
10_V	17_P	0.520	1.00
320_L	395_A	0.519	1.00
302_P	428_M	0.519	1.00
120_R	193_I	0.519	1.00
34_V	224_T	0.519	1.00
419_L	423_R	0.518	1.00
188_V	193_I	0.517	1.00
45_T	203_P	0.517	1.00
134_L	185_L	0.517	1.00
264_L	507_K	0.516	1.00
446_N	472_T	0.516	1.00
445_L	448_L	0.516	1.00
299_E	460_K	0.515	1.00
276_E	328_L	0.515	1.00
9_L	16_A	0.513	1.00
488_E	492_N	0.512	1.00
204_E	219_V	0.512	1.00
396_L	431_R	0.512	1.00
239_L	242_V	0.510	1.00
111_A	164_T	0.510	1.00
282_E	510_K	0.509	1.00
441_A	445_L	0.509	1.00
54_N	435_D	0.508	1.00
60_V	64_F	0.507	1.00
42_D	220_N	0.506	1.00
474_I	477_A	0.504	1.00
420_D	423_R	0.503	1.00
118_W	157_V	0.503	1.00
32_Q	241_Q	0.503	1.00
272_I	506_I	0.503	1.00
341_K	481_N	0.503	1.00
341_K	344_S	0.503	1.00
366_L	377_L	0.502	1.00
292_E	503_Q	0.502	1.00
229_P	235_Q	0.502	1.00
346_T	489_V	0.501	1.00
310_R	355_M	0.501	1.00
16_A	21_A	0.501	1.00
449_K	491_I	0.501	1.00
97_L	111_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4fajA	1	0.9252	100	0.131	Contact Map
3zs6A	1	0.9383	100	0.137	Contact Map
4qflA	1	0.9028	100	0.139	Contact Map
1jetA	1	0.957	100	0.142	Contact Map
4tozA	1	0.957	100	0.142	Contact Map
4gl8A	1	0.9178	100	0.155	Contact Map
1xocA	2	0.8991	100	0.16	Contact Map
4wedA	1	0.8598	100	0.168	Contact Map
2wolA	1	0.9645	100	0.18	Contact Map
3drfA	1	0.9121	100	0.184	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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