GLCA - ECOLI - GREMLIN Contacts

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GLCA - Glycolate permease GlcA

UniProt:	Q46839	Sequences: MVTWTQMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGAITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVFLYKLTVASGQFDIIRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLCLIANTAPVAFGALGVPILVAGQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWKGVKETWPAALVAGGSFAVTQFFTSNYIGPELPDITSALVSIVSLALFLKVWRPKNTETAISMGQSAGAMVVNKPSSGGPVPSEYSLGQIIRAWSPFLILTVLVTIWTMKPFKALFAPGGAFYSLVINFQIPHLHQQVLKAAPIVAQPTPMDAVFKFDPLSAGGTAIFIAAIISIFILGVGIKKGIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMFPFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMISPQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGIITLLQAYVFTGMLVS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12995
Length:	560 (502)
Sequences:	1564 (973)
Seq/√Len:	43.4

ECOLI - GLCA LLDP
BACSU - LUTP LCTP
HALSA - Q9HHI2
SULSO - Q7LX72

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
524_R	527_E	6.393	1.00
52_L	56_F	5.188	1.00
27_F	49_L	4.604	1.00
450_F	454_S	4.317	1.00
496_A	547_T	4.312	1.00
264_L	268_V	4.089	1.00
237_T	257_V	3.842	1.00
411_I	414_K	3.836	1.00
55_I	65_A	3.832	1.00
51_I	65_A	3.662	1.00
229_V	265_F	3.515	1.00
389_I	393_F	3.325	1.00
456_F	540_A	3.252	1.00
549_L	553_V	3.176	1.00
407_A	411_I	3.104	1.00
111_T	116_L	3.081	1.00
97_S	397_V	3.020	1.00
30_V	35_L	3.007	1.00
162_I	213_M	2.985	1.00
124_S	258_S	2.983	1.00
51_I	429_V	2.956	1.00
96_A	408_E	2.914	1.00
540_A	544_G	2.894	1.00
47_L	69_A	2.825	1.00
180_A	476_G	2.804	1.00
27_F	31_A	2.768	1.00
53_I	57_A	2.695	1.00
92_K	412_S	2.606	1.00
320_L	386_I	2.603	1.00
197_R	243_N	2.587	1.00
488_V	493_L	2.553	1.00
73_F	421_G	2.478	1.00
391_S	395_L	2.468	1.00
215_D	219_G	2.321	1.00
96_A	401_K	2.287	1.00
20_V	57_A	2.276	1.00
302_Y	306_Q	2.261	1.00
400_K	404_G	2.220	1.00
37_L	41_V	2.178	1.00
403_I	407_A	2.177	1.00
253_T	257_V	2.176	1.00
387_A	391_S	2.166	1.00
233_S	261_S	2.152	1.00
392_I	402_G	2.138	1.00
308_I	312_S	2.120	0.99
305_G	309_R	2.117	0.99
48_I	52_L	2.116	0.99
236_V	240_F	2.112	0.99
222_E	273_N	2.107	0.99
197_R	239_F	2.100	0.99
147_V	519_T	2.097	0.99
177_I	195_A	2.081	0.99
545_I	549_L	2.075	0.99
70_G	356_L	2.065	0.99
312_S	394_I	2.045	0.99
157_A	515_A	2.006	0.99
398_G	401_K	2.000	0.99
541_S	545_I	1.989	0.99
480_S	494_V	1.987	0.99
204_V	235_A	1.982	0.99
194_M	491_T	1.968	0.99
456_F	544_G	1.944	0.99
309_R	396_G	1.939	0.99
225_P	269_W	1.873	0.99
324_W	383_A	1.835	0.98
101_D	104_R	1.826	0.98
399_I	403_I	1.821	0.98
469_T	504_G	1.811	0.98
332_L	335_P	1.798	0.98
180_A	494_V	1.794	0.98
329_F	332_L	1.793	0.98
308_I	315_L	1.790	0.98
30_V	34_V	1.767	0.98
81_A	417_I	1.755	0.98
205_L	208_F	1.751	0.98
476_G	494_V	1.747	0.98
18_A	442_V	1.735	0.98
233_S	258_S	1.720	0.98
208_F	227_A	1.699	0.98
430_T	436_S	1.692	0.97
116_L	226_A	1.691	0.97
168_V	468_D	1.683	0.97
169_A	195_A	1.673	0.97
240_F	244_Y	1.671	0.97
330_K	334_A	1.650	0.97
122_G	210_L	1.635	0.97
239_F	244_Y	1.633	0.97
96_A	404_G	1.625	0.97
90_L	388_A	1.618	0.97
241_T	253_T	1.614	0.97
345_N	373_K	1.613	0.97
45_I	48_I	1.611	0.97
178_L	247_P	1.606	0.96
233_S	257_V	1.601	0.96
204_V	231_G	1.601	0.96
260_V	264_L	1.583	0.96
44_A	422_M	1.566	0.96
195_A	499_S	1.564	0.96
303_S	306_Q	1.561	0.96
31_A	37_L	1.560	0.96
31_A	45_I	1.558	0.96
306_Q	309_R	1.551	0.96
459_W	536_S	1.544	0.96
129_L	137_A	1.541	0.96
196_G	242_S	1.540	0.96
211_V	223_T	1.536	0.95
118_V	159_L	1.529	0.95
505_K	511_S	1.521	0.95
344_I	377_L	1.518	0.95
181_G	186_I	1.514	0.95
468_D	501_G	1.488	0.95
106_S	311_W	1.466	0.94
180_A	191_I	1.435	0.93
198_Q	546_I	1.433	0.93
42_A	128_L	1.430	0.93
147_V	521_M	1.422	0.93
71_Y	432_Y	1.417	0.93
38_K	42_A	1.413	0.93
226_A	265_F	1.392	0.92
89_F	388_A	1.389	0.92
355_V	370_A	1.381	0.92
224_W	227_A	1.380	0.92
265_F	269_W	1.380	0.92
548_L	552_Y	1.369	0.92
187_D	190_H	1.368	0.92
198_Q	550_Q	1.361	0.91
68_A	71_Y	1.359	0.91
137_A	526_S	1.357	0.91
186_I	491_T	1.347	0.91
122_G	126_G	1.344	0.91
386_I	390_I	1.329	0.90
230_A	262_L	1.328	0.90
20_V	23_I	1.326	0.90
92_K	409_T	1.324	0.90
114_Q	277_A	1.323	0.90
225_P	271_P	1.320	0.90
181_G	188_P	1.316	0.90
452_F	541_S	1.308	0.90
165_T	506_M	1.298	0.89
119_L	230_A	1.288	0.89
237_T	254_S	1.288	0.89
172_A	175_V	1.277	0.89
55_I	62_I	1.275	0.89
193_A	243_N	1.265	0.88
56_F	62_I	1.264	0.88
122_G	163_A	1.263	0.88
154_L	315_L	1.257	0.88
126_G	163_A	1.250	0.88
201_F	546_I	1.244	0.87
179_V	182_Q	1.242	0.87
198_Q	499_S	1.240	0.87
229_V	261_S	1.235	0.87
105_S	302_Y	1.234	0.87
158_G	531_Y	1.233	0.87
512_I	529_F	1.231	0.87
127_A	167_P	1.230	0.87
67_A	348_I	1.228	0.87
95_V	101_D	1.225	0.86
397_V	401_K	1.224	0.86
239_F	243_N	1.222	0.86
56_F	59_K	1.211	0.86
97_S	173_L	1.209	0.86
122_G	195_A	1.206	0.86
463_F	532_T	1.203	0.85
234_F	251_D	1.202	0.85
237_T	253_T	1.190	0.85
534_K	538_I	1.190	0.85
503_T	539_F	1.175	0.84
154_L	531_Y	1.174	0.84
392_I	396_G	1.173	0.84
205_L	538_I	1.169	0.84
332_L	344_I	1.169	0.84
476_G	480_S	1.168	0.84
90_L	317_L	1.167	0.84
446_T	449_M	1.158	0.83
199_L	238_Q	1.154	0.83
212_A	220_V	1.153	0.83
277_A	280_M	1.150	0.83
202_L	542_V	1.147	0.83
158_G	528_L	1.147	0.83
320_L	387_A	1.145	0.82
175_V	178_L	1.144	0.82
449_M	452_F	1.143	0.82
316_I	394_I	1.142	0.82
507_I	533_V	1.134	0.82
312_S	315_L	1.133	0.82
114_Q	276_T	1.131	0.82
74_I	372_F	1.123	0.81
69_A	429_V	1.121	0.81
452_F	548_L	1.115	0.81
208_F	228_L	1.114	0.81
208_F	224_W	1.110	0.80
209_W	535_H	1.108	0.80
114_Q	151_F	1.106	0.80
347_Q	371_V	1.102	0.80
116_L	223_T	1.098	0.80
44_A	418_L	1.096	0.80
541_S	544_G	1.092	0.79
102_I	302_Y	1.090	0.79
184_T	494_V	1.087	0.79
83_I	172_A	1.085	0.79
46_T	426_F	1.083	0.79
92_K	408_E	1.079	0.79
119_L	227_A	1.073	0.78
376_P	379_A	1.072	0.78
118_V	214_M	1.070	0.78
265_F	268_V	1.064	0.78
98_G	156_A	1.061	0.77
117_Q	149_L	1.060	0.77
328_P	332_L	1.060	0.77
66_F	69_A	1.058	0.77
405_V	408_E	1.052	0.77
75_Y	428_F	1.048	0.76
86_A	406_F	1.046	0.76
196_G	243_N	1.045	0.76
375_D	378_S	1.039	0.76
55_I	260_V	1.038	0.76
67_A	70_G	1.036	0.76
47_L	133_A	1.035	0.76
169_A	468_D	1.034	0.75
516_C	528_L	1.030	0.75
119_L	262_L	1.030	0.75
329_F	333_F	1.030	0.75
89_F	402_G	1.029	0.75
400_K	541_S	1.029	0.75
232_G	389_I	1.023	0.75
112_D	274_T	1.017	0.74
534_K	537_L	1.014	0.74
19_L	23_I	1.012	0.74
73_F	77_L	1.012	0.74
16_L	57_A	1.006	0.73
121_I	142_T	1.005	0.73
446_T	453_F	1.002	0.73
93_L	405_V	0.999	0.73
437_T	481_T	0.996	0.73
73_F	425_A	0.995	0.73
388_A	402_G	0.991	0.72
51_I	55_I	0.987	0.72
83_I	175_V	0.983	0.72
190_H	491_T	0.980	0.71
37_L	45_I	0.977	0.71
185_G	425_A	0.975	0.71
312_S	316_I	0.970	0.71
81_A	420_I	0.969	0.71
179_V	439_L	0.969	0.71
116_L	485_Q	0.968	0.70
472_N	498_T	0.967	0.70
260_V	272_K	0.963	0.70
227_A	232_G	0.962	0.70
406_F	410_L	0.961	0.70
23_I	49_L	0.959	0.70
68_A	456_F	0.959	0.70
177_I	191_I	0.959	0.70
144_A	442_V	0.958	0.70
71_Y	428_F	0.958	0.70
451_P	544_G	0.956	0.70
424_L	478_L	0.956	0.70
323_I	329_F	0.951	0.69
27_F	46_T	0.949	0.69
458_G	475_F	0.947	0.69
225_P	268_V	0.947	0.69
483_A	506_M	0.946	0.69
244_Y	489_S	0.943	0.68
97_S	395_L	0.943	0.68
68_A	432_Y	0.939	0.68
76_G	419_S	0.937	0.68
53_I	58_F	0.935	0.68
204_V	232_G	0.934	0.68
36_R	527_E	0.932	0.68
303_S	541_S	0.931	0.67
80_I	170_F	0.929	0.67
477_S	480_S	0.928	0.67
82_W	382_T	0.928	0.67
325_T	378_S	0.926	0.67
216_G	438_T	0.925	0.67
169_A	502_V	0.922	0.67
430_T	435_M	0.917	0.66
129_L	141_I	0.916	0.66
232_G	236_V	0.915	0.66
200_P	239_F	0.914	0.66
52_L	59_K	0.912	0.66
136_G	171_G	0.911	0.66
66_F	545_I	0.910	0.66
58_F	438_T	0.909	0.66
225_P	265_F	0.905	0.65
457_L	478_L	0.903	0.65
20_V	53_I	0.900	0.65
26_I	30_V	0.899	0.65
124_S	259_I	0.897	0.65
117_Q	151_F	0.894	0.64
167_P	468_D	0.894	0.64
398_G	484_Q	0.894	0.64
309_R	312_S	0.894	0.64
163_A	210_L	0.894	0.64
191_I	494_V	0.891	0.64
527_E	530_R	0.890	0.64
408_E	411_I	0.890	0.64
32_L	36_R	0.890	0.64
179_V	473_A	0.888	0.64
85_V	410_L	0.885	0.64
412_S	416_P	0.884	0.63
248_E	325_T	0.880	0.63
456_F	537_L	0.877	0.63
441_L	485_Q	0.876	0.63
92_K	405_V	0.874	0.63
459_W	540_A	0.871	0.62
541_S	549_L	0.871	0.62
45_I	477_S	0.870	0.62
102_I	306_Q	0.868	0.62
166_A	251_D	0.867	0.62
165_T	468_D	0.865	0.62
165_T	502_V	0.863	0.62
350_H	369_D	0.862	0.61
316_I	390_I	0.862	0.61
227_A	231_G	0.861	0.61
128_L	384_I	0.859	0.61
215_D	220_V	0.857	0.61
505_K	510_Q	0.855	0.61
31_A	314_F	0.855	0.61
238_Q	468_D	0.849	0.60
146_L	213_M	0.848	0.60
514_V	526_S	0.845	0.60
440_A	481_T	0.844	0.60
192_G	419_S	0.844	0.60
135_F	172_A	0.836	0.59
193_A	239_F	0.834	0.59
514_V	535_H	0.834	0.59
240_F	542_V	0.832	0.59
241_T	257_V	0.832	0.59
62_I	268_V	0.831	0.59
419_S	501_G	0.828	0.58
156_A	311_W	0.826	0.58
149_L	495_A	0.825	0.58
191_I	480_S	0.825	0.58
197_R	550_Q	0.822	0.58
80_I	135_F	0.819	0.57
128_L	318_T	0.819	0.57
500_G	504_G	0.818	0.57
247_P	250_P	0.817	0.57
299_P	524_R	0.816	0.57
233_S	237_T	0.816	0.57
146_L	228_L	0.812	0.57
167_P	195_A	0.810	0.57
348_I	495_A	0.809	0.57
384_I	509_P	0.808	0.56
215_D	221_K	0.808	0.56
128_L	132_A	0.804	0.56
187_D	327_K	0.804	0.56
486_I	493_L	0.803	0.56
188_P	192_G	0.802	0.56
168_V	506_M	0.801	0.56
335_P	390_I	0.801	0.56
25_I	131_G	0.799	0.56
401_K	404_G	0.798	0.56
123_F	254_S	0.797	0.55
122_G	231_G	0.796	0.55
135_F	469_T	0.796	0.55
127_A	163_A	0.796	0.55
317_L	382_T	0.795	0.55
54_A	429_V	0.795	0.55
200_P	235_A	0.791	0.55
198_Q	201_F	0.787	0.54
468_D	499_S	0.787	0.54
17_S	57_A	0.786	0.54
121_I	125_F	0.785	0.54
26_I	346_F	0.784	0.54
151_F	451_P	0.784	0.54
443_L	446_T	0.783	0.54
300_S	304_L	0.783	0.54
135_F	467_S	0.781	0.54
247_P	262_L	0.780	0.54
275_E	278_I	0.779	0.54
189_F	192_G	0.779	0.54
316_I	387_A	0.778	0.54
399_I	404_G	0.776	0.53
130_E	171_G	0.775	0.53
542_V	546_I	0.771	0.53
230_A	233_S	0.771	0.53
121_I	149_L	0.768	0.53
280_M	456_F	0.765	0.52
411_I	541_S	0.764	0.52
163_A	167_P	0.762	0.52
173_L	325_T	0.762	0.52
28_F	46_T	0.762	0.52
132_A	172_A	0.762	0.52
38_K	41_V	0.761	0.52
36_R	42_A	0.759	0.52
114_Q	275_E	0.756	0.52
179_V	183_V	0.756	0.52
314_F	348_I	0.756	0.52
260_V	315_L	0.755	0.51
107_V	504_G	0.751	0.51
301_E	390_I	0.748	0.51
204_V	491_T	0.748	0.51
442_V	445_G	0.747	0.51
177_I	472_N	0.746	0.51
317_L	426_F	0.745	0.50
49_L	442_V	0.743	0.50
233_S	507_I	0.741	0.50
179_V	464_L	0.741	0.50
59_K	389_I	0.741	0.50
393_F	399_I	0.739	0.50
68_A	356_L	0.738	0.50
461_G	471_S	0.737	0.50
69_A	425_A	0.736	0.50
431_N	470_S	0.734	0.49
447_G	453_F	0.732	0.49
158_G	532_T	0.731	0.49
350_H	440_A	0.731	0.49
76_G	201_F	0.730	0.49
527_E	531_Y	0.730	0.49
49_L	52_L	0.730	0.49
239_F	251_D	0.728	0.49
95_V	104_R	0.728	0.49
505_K	514_V	0.726	0.49
415_W	418_L	0.724	0.48
232_G	237_T	0.724	0.48
88_V	105_S	0.723	0.48
297_P	300_S	0.721	0.48
48_I	347_Q	0.721	0.48
165_T	168_V	0.720	0.48
32_L	39_G	0.719	0.48
102_I	307_I	0.718	0.48
257_V	261_S	0.718	0.48
46_T	88_V	0.717	0.48
66_F	484_Q	0.716	0.48
174_G	246_G	0.716	0.48
48_I	51_I	0.713	0.47
334_A	375_D	0.710	0.47
483_A	488_V	0.709	0.47
45_I	49_L	0.709	0.47
267_K	394_I	0.705	0.47
169_A	238_Q	0.704	0.47
439_L	464_L	0.702	0.46
128_L	247_P	0.700	0.46
266_L	269_W	0.699	0.46
301_E	545_I	0.699	0.46
315_L	541_S	0.699	0.46
126_G	210_L	0.698	0.46
23_I	53_I	0.695	0.46
345_N	389_I	0.694	0.46
451_P	486_I	0.693	0.46
418_L	422_M	0.692	0.45
104_R	145_L	0.692	0.45
331_A	373_K	0.691	0.45
276_T	280_M	0.690	0.45
319_V	403_I	0.688	0.45
273_N	276_T	0.687	0.45
130_E	136_G	0.687	0.45
65_A	74_I	0.686	0.45
321_V	384_I	0.685	0.45
124_S	230_A	0.685	0.45
52_L	63_D	0.683	0.45
199_L	203_S	0.683	0.45
118_V	453_F	0.683	0.45
29_F	196_G	0.682	0.44
133_A	137_A	0.681	0.44
225_P	229_V	0.681	0.44
506_M	521_M	0.680	0.44
264_L	299_P	0.680	0.44
201_F	499_S	0.679	0.44
33_A	118_V	0.679	0.44
157_A	478_L	0.678	0.44
327_K	330_K	0.675	0.44
110_I	154_L	0.674	0.44
132_A	175_V	0.673	0.44
99_Q	307_I	0.673	0.44
238_Q	502_V	0.672	0.44
86_A	180_A	0.672	0.44
61_P	224_W	0.672	0.44
128_L	512_I	0.671	0.43
399_I	452_F	0.670	0.43
328_P	331_A	0.669	0.43
201_F	240_F	0.669	0.43
208_F	486_I	0.669	0.43
180_A	473_A	0.668	0.43
502_V	510_Q	0.665	0.43
47_L	51_I	0.664	0.43
403_I	411_I	0.664	0.43
122_G	139_V	0.663	0.43
29_F	527_E	0.661	0.43
200_P	251_D	0.661	0.43
450_F	486_I	0.661	0.43
321_V	324_W	0.660	0.42
391_S	397_V	0.658	0.42
497_N	505_K	0.658	0.42
56_F	297_P	0.658	0.42
231_G	235_A	0.657	0.42
194_M	492_L	0.657	0.42
439_L	514_V	0.654	0.42
207_P	497_N	0.651	0.42
192_G	247_P	0.650	0.41
154_L	216_G	0.650	0.41
298_V	369_D	0.645	0.41
141_I	474_L	0.644	0.41
500_G	507_I	0.643	0.41
498_T	502_V	0.643	0.41
77_L	355_V	0.642	0.41
85_V	89_F	0.642	0.41
117_Q	416_P	0.641	0.41
533_V	538_I	0.640	0.41
190_H	194_M	0.640	0.41
320_L	390_I	0.640	0.41
298_V	389_I	0.636	0.40
508_S	513_A	0.636	0.40
314_F	427_A	0.635	0.40
67_A	350_H	0.635	0.40
218_K	273_N	0.634	0.40
77_L	81_A	0.634	0.40
400_K	403_I	0.634	0.40
436_S	464_L	0.633	0.40
174_G	199_L	0.633	0.40
209_W	487_N	0.632	0.40
22_L	26_I	0.631	0.40
196_G	238_Q	0.631	0.40
257_V	329_F	0.631	0.40
211_V	227_A	0.629	0.40
154_L	385_F	0.627	0.39
129_L	427_A	0.626	0.39
22_L	439_L	0.626	0.39
432_Y	440_A	0.625	0.39
43_G	162_I	0.624	0.39
57_A	70_G	0.623	0.39
199_L	468_D	0.623	0.39
28_F	145_L	0.623	0.39
88_V	137_A	0.623	0.39
46_T	50_S	0.623	0.39
499_S	550_Q	0.621	0.39
120_L	266_L	0.620	0.39
300_S	407_A	0.618	0.39
446_T	528_L	0.618	0.39
97_S	457_L	0.616	0.38
305_G	319_V	0.616	0.38
26_I	228_L	0.614	0.38
302_Y	307_I	0.614	0.38
86_A	385_F	0.613	0.38
169_A	498_T	0.613	0.38
219_G	433_S	0.613	0.38
51_I	66_F	0.612	0.38
186_I	494_V	0.612	0.38
170_F	250_P	0.611	0.38
64_M	68_A	0.611	0.38
468_D	505_K	0.609	0.38
128_L	317_L	0.607	0.38
315_L	319_V	0.605	0.37
414_K	418_L	0.605	0.37
451_P	548_L	0.605	0.37
48_I	190_H	0.605	0.37
308_I	323_I	0.604	0.37
63_D	319_V	0.602	0.37
19_L	346_F	0.602	0.37
152_K	155_Y	0.602	0.37
126_G	166_A	0.600	0.37
178_L	242_S	0.599	0.37
155_Y	218_K	0.599	0.37
19_L	26_I	0.598	0.37
19_L	403_I	0.597	0.37
509_P	513_A	0.597	0.37
25_I	463_F	0.596	0.37
533_V	537_L	0.596	0.37
117_Q	444_A	0.596	0.37
254_S	316_I	0.595	0.36
239_F	546_I	0.595	0.36
117_Q	317_L	0.594	0.36
200_P	203_S	0.594	0.36
31_A	233_S	0.593	0.36
434_G	549_L	0.593	0.36
314_F	384_I	0.592	0.36
83_I	256_L	0.592	0.36
59_K	62_I	0.592	0.36
128_L	160_C	0.592	0.36
389_I	548_L	0.591	0.36
82_W	326_M	0.590	0.36
486_I	548_L	0.590	0.36
215_D	515_A	0.588	0.36
437_T	441_L	0.588	0.36
470_S	473_A	0.587	0.36
85_V	116_L	0.587	0.36
20_V	177_I	0.586	0.36
398_G	452_F	0.585	0.36
15_G	308_I	0.583	0.35
245_I	253_T	0.583	0.35
309_R	390_I	0.583	0.35
86_A	384_I	0.582	0.35
323_I	334_A	0.581	0.35
122_G	503_T	0.580	0.35
112_D	255_A	0.580	0.35
19_L	57_A	0.580	0.35
172_A	177_I	0.579	0.35
48_I	146_L	0.578	0.35
212_A	223_T	0.577	0.35
427_A	509_P	0.576	0.35
39_G	104_R	0.576	0.35
36_R	101_D	0.576	0.35
189_F	193_A	0.576	0.35
58_F	412_S	0.575	0.35
122_G	208_F	0.574	0.35
267_K	301_E	0.574	0.35
154_L	158_G	0.574	0.35
109_S	265_F	0.573	0.35
183_V	473_A	0.573	0.35
518_A	528_L	0.572	0.34
420_I	511_S	0.572	0.34
267_K	548_L	0.572	0.34
91_Y	95_V	0.572	0.34
114_Q	155_Y	0.571	0.34
220_V	373_K	0.571	0.34
430_T	509_P	0.571	0.34
21_A	489_S	0.570	0.34
444_A	478_L	0.570	0.34
70_G	316_I	0.570	0.34
128_L	209_W	0.569	0.34
468_D	472_N	0.569	0.34
427_A	470_S	0.569	0.34
63_D	394_I	0.568	0.34
102_I	225_P	0.568	0.34
120_L	323_I	0.568	0.34
450_F	532_T	0.568	0.34
131_G	311_W	0.568	0.34
55_I	66_F	0.568	0.34
493_L	496_A	0.567	0.34
36_R	95_V	0.567	0.34
37_L	42_A	0.566	0.34
104_R	500_G	0.565	0.34
396_G	529_F	0.565	0.34
169_A	177_I	0.564	0.34
167_P	234_F	0.563	0.34
181_G	191_I	0.563	0.34
404_G	407_A	0.562	0.34
166_A	502_V	0.561	0.34
329_F	355_V	0.561	0.34
487_N	490_D	0.560	0.33
88_V	103_I	0.560	0.33
103_I	311_W	0.560	0.33
457_L	473_A	0.559	0.33
439_L	540_A	0.558	0.33
141_I	213_M	0.558	0.33
197_R	242_S	0.557	0.33
188_P	323_I	0.557	0.33
123_F	250_P	0.556	0.33
89_F	406_F	0.556	0.33
15_G	22_L	0.556	0.33
480_S	484_Q	0.556	0.33
82_W	385_F	0.556	0.33
192_G	499_S	0.556	0.33
88_V	173_L	0.554	0.33
83_I	90_L	0.554	0.33
193_A	196_G	0.554	0.33
139_V	515_A	0.554	0.33
237_T	241_T	0.553	0.33
70_G	393_F	0.553	0.33
23_I	394_I	0.552	0.33
323_I	333_F	0.552	0.33
62_I	398_G	0.552	0.33
329_F	489_S	0.550	0.33
304_L	398_G	0.549	0.33
240_F	257_V	0.549	0.33
177_I	498_T	0.548	0.32
26_I	66_F	0.546	0.32
537_L	541_S	0.545	0.32
501_G	536_S	0.545	0.32
224_W	303_S	0.545	0.32
220_V	323_I	0.545	0.32
241_T	245_I	0.544	0.32
455_P	548_L	0.542	0.32
301_E	344_I	0.542	0.32
21_A	39_G	0.542	0.32
221_K	263_A	0.541	0.32
54_A	389_I	0.541	0.32
307_I	315_L	0.540	0.32
226_A	235_A	0.540	0.32
99_Q	306_Q	0.540	0.32
186_I	348_I	0.540	0.32
267_K	304_L	0.538	0.32
85_V	409_T	0.538	0.32
452_F	455_P	0.538	0.32
132_A	159_L	0.536	0.31
117_Q	314_F	0.535	0.31
276_T	279_S	0.535	0.31
232_G	408_E	0.535	0.31
198_Q	495_A	0.535	0.31
211_V	355_V	0.534	0.31
183_V	476_G	0.534	0.31
22_L	443_L	0.533	0.31
327_K	331_A	0.533	0.31
93_L	397_V	0.533	0.31
114_Q	278_I	0.531	0.31
201_F	241_T	0.531	0.31
260_V	369_D	0.530	0.31
250_P	254_S	0.530	0.31
110_I	319_V	0.530	0.31
127_A	462_V	0.529	0.31
192_G	236_V	0.529	0.31
164_N	510_Q	0.529	0.31
403_I	449_M	0.528	0.31
398_G	403_I	0.528	0.31
137_A	469_T	0.528	0.31
301_E	488_V	0.527	0.31
127_A	164_N	0.527	0.31
455_P	509_P	0.527	0.31
162_I	518_A	0.526	0.31
118_V	122_G	0.525	0.31
16_L	25_I	0.524	0.30
21_A	234_F	0.524	0.30
510_Q	514_V	0.523	0.30
242_S	250_P	0.523	0.30
304_L	308_I	0.523	0.30
347_Q	390_I	0.522	0.30
119_L	219_G	0.522	0.30
159_L	376_P	0.520	0.30
87_A	133_A	0.520	0.30
387_A	480_S	0.520	0.30
419_S	440_A	0.519	0.30
41_V	256_L	0.518	0.30
178_L	182_Q	0.518	0.30
49_L	244_Y	0.518	0.30
47_L	422_M	0.518	0.30
147_V	202_L	0.518	0.30
468_D	502_V	0.517	0.30
441_L	478_L	0.517	0.30
368_M	464_L	0.516	0.30
280_M	386_I	0.515	0.30
358_A	439_L	0.515	0.30
254_S	320_L	0.513	0.30
344_I	376_P	0.512	0.29
196_G	251_D	0.512	0.29
29_F	470_S	0.512	0.29
429_V	440_A	0.510	0.29
514_V	519_T	0.510	0.29
252_I	452_F	0.509	0.29
334_A	454_S	0.509	0.29
88_V	314_F	0.509	0.29
31_A	309_R	0.508	0.29
416_P	501_G	0.508	0.29
138_P	444_A	0.508	0.29
124_S	127_A	0.508	0.29
161_L	506_M	0.506	0.29
543_I	553_V	0.506	0.29
159_L	214_M	0.505	0.29
53_I	56_F	0.504	0.29
414_K	504_G	0.504	0.29
84_I	542_V	0.503	0.29
428_F	432_Y	0.503	0.29
183_V	229_V	0.502	0.29
110_I	265_F	0.501	0.29
213_M	386_I	0.501	0.29
512_I	547_T	0.501	0.29
209_W	550_Q	0.501	0.29
40_H	415_W	0.501	0.29
31_A	34_V	0.501	0.29
372_F	517_A	0.500	0.29
463_F	512_I	0.500	0.29
468_D	506_M	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r0cA	3	0.8	99.8	0.88	Contact Map
4r1iA	2	0.8214	99.7	0.886	Contact Map
4f35D	2	0.7179	99.6	0.891	Contact Map
3qe7A	2	0.4536	12.9	0.982	Contact Map
1j4nA	4	0.3696	8.6	0.984	Contact Map
3qnqA	2	0.4982	8.3	0.984	Contact Map
2i68A	2	0.1304	6.6	0.985	Contact Map
4x5mA	2	0.1607	6.2	0.985	Contact Map
5a63B	1	0.1518	5.3	0.985	Contact Map
4u9nA	2	0.2071	4.9	0.986	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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