BGLA - ECOLI - GREMLIN Contacts

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BGLA - 6-phospho-beta-glucosidase BglA

UniProt:	Q46829	Sequences: MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAEVVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFVASALAVKAARRINPEMKVGCMLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRYALCELYERYQRPLFIVENGFGAYDKVEEDGSINDDYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFNWYKEVIASNGEKL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13079
Length:	479 (437)
Sequences:	6776 (4232)
Seq/√Len:	202.4

ECOLI - BGLA ASCB BGLB
BACSU - BGLA BGLC BGLH GMUD
SULSO - BGAL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
30_G	109_E	4.234	1.00
393_N	463_K	4.009	1.00
119_D	171_K	3.561	1.00
408_M	419_L	3.148	1.00
115_D	171_K	3.114	1.00
81_A	124_Y	3.095	1.00
74_K	120_E	3.009	1.00
132_L	164_V	2.888	1.00
115_D	167_R	2.877	1.00
461_R	465_F	2.859	1.00
120_E	123_K	2.835	1.00
108_E	112_K	2.817	1.00
68_D	71_G	2.816	1.00
53_K	61_Y	2.759	1.00
112_K	116_D	2.745	1.00
98_F	163_V	2.702	1.00
108_E	167_R	2.697	1.00
407_E	410_K	2.688	1.00
316_Y	404_H	2.624	1.00
29_K	71_G	2.607	1.00
251_S	256_D	2.565	1.00
162_E	166_E	2.552	1.00
16_G	85_F	2.438	1.00
401_L	424_P	2.339	1.00
359_R	415_D	2.289	1.00
78_K	124_Y	2.287	1.00
399_D	403_A	2.245	1.00
363_C	415_D	2.244	1.00
155_D	224_L	2.228	1.00
229_A	238_V	2.203	1.00
42_G	64_H	2.196	1.00
395_D	463_K	2.171	1.00
446_Y	460_S	2.140	1.00
227_K	231_R	2.138	1.00
74_K	116_D	2.123	1.00
118_F	168_Y	2.110	1.00
69_F	113_F	2.085	1.00
87_C	423_T	2.077	1.00
127_E	173_K	2.038	1.00
77_I	117_M	1.987	1.00
387_E	391_S	1.984	1.00
469_K	473_A	1.974	1.00
92_I	130_I	1.971	1.00
69_F	88_F	1.952	1.00
158_V	228_A	1.905	1.00
109_E	112_K	1.887	1.00
281_S	285_N	1.881	1.00
122_L	171_K	1.878	1.00
39_V	139_L	1.877	1.00
162_E	228_A	1.870	1.00
216_H	279_Y	1.864	1.00
90_T	118_F	1.861	1.00
162_E	232_I	1.858	1.00
35_S	95_T	1.824	1.00
77_I	124_Y	1.820	1.00
27_W	34_P	1.802	1.00
229_A	236_M	1.791	1.00
301_L	305_R	1.782	1.00
115_D	119_D	1.772	1.00
34_P	39_V	1.748	1.00
359_R	410_K	1.736	1.00
248_Y	360_Y	1.718	1.00
120_E	124_Y	1.697	1.00
18_V	23_V	1.685	1.00
299_G	302_D	1.671	1.00
14_W	475_N	1.662	1.00
119_D	122_L	1.654	1.00
127_E	174_Y	1.651	1.00
121_L	126_I	1.642	1.00
140_H	144_Q	1.629	1.00
233_N	236_M	1.629	1.00
90_T	117_M	1.627	1.00
26_G	29_K	1.626	1.00
356_V	407_E	1.626	1.00
362_L	417_V	1.620	1.00
158_V	224_L	1.595	1.00
118_F	122_L	1.590	1.00
115_D	168_Y	1.579	1.00
78_K	120_E	1.579	1.00
145_Y	156_F	1.568	1.00
364_E	368_R	1.551	1.00
316_Y	357_G	1.551	1.00
359_R	363_C	1.549	1.00
276_R	370_Q	1.543	1.00
298_D	301_L	1.537	1.00
73_Y	116_D	1.534	1.00
77_I	120_E	1.531	1.00
470_E	473_A	1.529	1.00
47_V	50_E	1.529	1.00
265_R	282_Y	1.528	1.00
21_H	63_N	1.525	1.00
374_F	420_M	1.522	1.00
13_L	87_C	1.522	1.00
153_V	156_F	1.515	1.00
176_M	241_M	1.510	1.00
300_D	303_V	1.493	1.00
278_Y	305_R	1.489	1.00
87_C	129_V	1.477	1.00
151_R	300_D	1.475	1.00
72_H	75_E	1.468	1.00
149_T	210_T	1.462	1.00
215_L	270_F	1.460	1.00
165_F	229_A	1.458	1.00
448_N	456_D	1.457	1.00
33_G	101_G	1.445	1.00
18_V	88_F	1.445	1.00
271_T	312_L	1.442	1.00
269_V	283_V	1.437	1.00
111_L	163_V	1.426	1.00
348_D	383_Y	1.421	1.00
302_D	306_E	1.418	1.00
176_M	311_Y	1.405	1.00
77_I	121_L	1.403	1.00
80_F	85_F	1.399	1.00
366_Y	371_R	1.395	1.00
170_H	233_N	1.394	1.00
409_K	413_T	1.391	1.00
378_N	422_Y	1.379	1.00
98_F	106_P	1.375	1.00
358_L	408_M	1.375	1.00
146_G	150_N	1.372	1.00
82_E	465_F	1.360	1.00
424_P	444_F	1.359	1.00
228_A	231_R	1.349	1.00
90_T	130_I	1.342	1.00
173_K	235_E	1.332	1.00
26_G	71_G	1.329	1.00
129_V	423_T	1.329	1.00
151_R	217_H	1.324	1.00
39_V	144_Q	1.317	1.00
240_C	274_Q	1.316	1.00
92_I	164_V	1.314	1.00
68_D	72_H	1.308	1.00
467_W	471_V	1.308	1.00
362_L	408_M	1.304	1.00
174_Y	237_K	1.301	1.00
470_E	474_S	1.298	1.00
461_R	466_N	1.278	1.00
278_Y	284_L	1.273	1.00
278_Y	370_Q	1.263	1.00
155_D	158_V	1.252	1.00
178_F	218_Q	1.248	1.00
204_H	210_T	1.231	1.00
139_L	143_Q	1.228	1.00
152_K	155_D	1.228	1.00
402_R	406_E	1.225	1.00
405_I	408_M	1.219	1.00
178_F	221_A	1.206	1.00
102_D	156_F	1.204	1.00
403_A	406_E	1.204	1.00
78_K	82_E	1.202	1.00
466_N	469_K	1.199	1.00
92_I	97_I	1.198	1.00
302_D	305_R	1.196	1.00
111_L	167_R	1.192	1.00
363_C	417_V	1.188	1.00
184_Q	218_Q	1.183	1.00
80_F	445_I	1.174	1.00
102_D	145_Y	1.174	1.00
100_K	140_H	1.170	1.00
9_P	412_V	1.170	1.00
69_F	117_M	1.168	1.00
67_V	428_I	1.159	1.00
73_Y	120_E	1.158	1.00
165_F	225_A	1.155	1.00
387_E	393_N	1.152	1.00
115_D	170_H	1.146	1.00
391_S	463_K	1.141	1.00
33_G	140_H	1.139	1.00
227_K	306_E	1.139	1.00
137_M	153_V	1.135	1.00
166_E	232_I	1.129	1.00
249_P	260_A	1.128	1.00
249_P	257_V	1.125	1.00
366_Y	418_D	1.122	1.00
132_L	157_F	1.122	1.00
27_W	32_K	1.119	1.00
161_A	225_A	1.110	1.00
139_L	144_Q	1.110	1.00
18_V	90_T	1.110	1.00
148_W	153_V	1.106	1.00
264_M	364_E	1.100	1.00
26_G	30_G	1.095	1.00
272_D	276_R	1.094	1.00
254_P	258_M	1.093	1.00
158_V	225_A	1.091	1.00
272_D	368_R	1.091	1.00
449_K	457_M	1.089	1.00
165_F	238_V	1.089	1.00
409_K	412_V	1.089	1.00
299_G	303_V	1.084	1.00
468_Y	472_I	1.075	1.00
390_G	460_S	1.074	1.00
356_V	360_Y	1.071	1.00
158_V	162_E	1.065	1.00
227_K	307_G	1.059	1.00
254_P	257_V	1.056	1.00
145_Y	152_K	1.053	1.00
247_L	263_S	1.052	1.00
111_L	115_D	1.052	1.00
258_M	262_E	1.051	1.00
82_E	461_R	1.049	1.00
244_M	361_A	1.048	1.00
118_F	171_K	1.047	1.00
226_V	230_R	1.045	1.00
8_L	412_V	1.044	1.00
104_A	159_R	1.040	1.00
106_P	163_V	1.040	1.00
152_K	156_F	1.038	1.00
65_E	449_K	1.038	1.00
72_H	458_S	1.032	1.00
33_G	99_P	1.032	1.00
228_A	232_I	1.029	1.00
229_A	234_P	1.029	1.00
118_F	130_I	1.026	1.00
161_A	228_A	1.026	1.00
115_D	122_L	1.023	1.00
256_D	324_A	1.023	1.00
386_V	460_S	1.023	1.00
255_D	356_V	1.023	1.00
224_L	228_A	1.023	1.00
255_D	324_A	1.022	1.00
217_H	220_V	1.019	1.00
300_D	305_R	1.014	1.00
100_K	105_Q	1.010	1.00
8_L	409_K	1.008	1.00
358_L	419_L	1.006	1.00
65_E	457_M	1.005	1.00
224_L	304_L	1.004	1.00
346_A	352_Q	1.004	1.00
398_I	467_W	1.001	1.00
250_Y	323_K	1.001	1.00
253_N	257_V	0.995	1.00
358_L	375_I	0.991	1.00
347_S	380_F	0.988	1.00
448_N	458_S	0.987	1.00
345_K	403_A	0.984	1.00
349_W	381_G	0.983	1.00
265_R	283_V	0.982	1.00
261_Q	265_R	0.981	1.00
129_V	174_Y	0.979	1.00
97_I	163_V	0.977	1.00
16_G	80_F	0.976	1.00
11_D	420_M	0.974	1.00
399_D	402_R	0.972	1.00
345_K	396_Y	0.972	1.00
278_Y	281_S	0.971	1.00
156_F	159_R	0.969	1.00
206_N	210_T	0.968	0.99
163_V	167_R	0.967	0.99
383_Y	439_S	0.966	0.99
301_L	304_L	0.965	0.99
164_V	168_Y	0.964	0.99
169_K	236_M	0.962	0.99
263_S	322_V	0.962	0.99
257_V	260_A	0.954	0.99
129_V	374_F	0.953	0.99
239_G	313_G	0.945	0.99
146_G	149_T	0.944	0.99
137_M	147_S	0.941	0.99
275_L	371_R	0.940	0.99
154_V	224_L	0.939	0.99
13_L	129_V	0.938	0.99
382_A	396_Y	0.938	0.99
32_K	95_T	0.936	0.99
165_F	236_M	0.934	0.99
285_N	288_E	0.934	0.99
23_V	69_F	0.933	0.99
340_P	346_A	0.932	0.99
86_K	475_N	0.930	0.99
258_M	261_Q	0.929	0.99
226_V	238_V	0.911	0.99
116_D	119_D	0.911	0.99
112_K	115_D	0.906	0.99
75_E	78_K	0.901	0.99
161_A	165_F	0.895	0.99
380_F	396_Y	0.893	0.99
441_R	449_K	0.889	0.99
194_Y	198_G	0.887	0.99
366_Y	370_Q	0.887	0.99
31_G	107_N	0.885	0.99
85_F	427_C	0.885	0.99
151_R	301_L	0.884	0.99
428_I	447_V	0.884	0.99
185_R	214_V	0.883	0.99
345_K	399_D	0.883	0.99
143_Q	204_H	0.877	0.99
247_L	260_A	0.876	0.99
264_M	268_Y	0.873	0.99
252_C	257_V	0.873	0.99
261_Q	282_Y	0.872	0.99
111_L	164_V	0.872	0.99
115_D	118_F	0.871	0.99
386_V	390_G	0.871	0.99
61_Y	439_S	0.870	0.99
471_V	475_N	0.869	0.99
225_A	228_A	0.869	0.99
242_L	271_T	0.869	0.99
145_Y	153_V	0.868	0.99
412_V	419_L	0.863	0.99
78_K	81_A	0.860	0.99
208_E	290_R	0.856	0.99
349_W	440_K	0.856	0.99
101_G	140_H	0.855	0.99
381_G	440_K	0.854	0.99
133_S	137_M	0.853	0.99
176_M	313_G	0.853	0.99
239_G	311_Y	0.852	0.99
113_F	117_M	0.850	0.99
170_H	236_M	0.849	0.99
291_G	294_I	0.847	0.99
298_D	305_R	0.846	0.99
122_L	128_P	0.845	0.99
406_E	410_K	0.840	0.99
167_R	171_K	0.837	0.99
229_A	233_N	0.837	0.99
178_F	184_Q	0.836	0.99
160_F	164_V	0.835	0.99
169_K	233_N	0.832	0.98
358_L	407_E	0.828	0.98
386_V	391_S	0.827	0.98
272_D	369_Y	0.826	0.98
395_D	399_D	0.826	0.98
466_N	470_E	0.826	0.98
303_V	306_E	0.825	0.98
102_D	144_Q	0.824	0.98
392_I	460_S	0.823	0.98
286_E	290_R	0.821	0.98
363_C	367_E	0.821	0.98
356_V	410_K	0.820	0.98
354_D	357_G	0.819	0.98
224_L	227_K	0.819	0.98
154_V	220_V	0.817	0.98
133_S	136_E	0.816	0.98
285_N	289_R	0.814	0.98
80_F	126_I	0.813	0.98
149_T	204_H	0.811	0.98
222_S	226_V	0.810	0.98
82_E	469_K	0.807	0.98
7_T	10_K	0.805	0.98
183_N	243_A	0.800	0.98
36_I	137_M	0.800	0.98
314_F	373_L	0.798	0.98
387_E	390_G	0.795	0.98
318_M	352_Q	0.794	0.98
177_T	240_C	0.793	0.98
13_L	127_E	0.792	0.98
23_V	67_V	0.791	0.98
32_K	35_S	0.789	0.98
340_P	344_V	0.788	0.98
14_W	405_I	0.787	0.98
9_P	418_D	0.783	0.98
244_M	314_F	0.781	0.98
463_K	466_N	0.779	0.98
157_F	161_A	0.779	0.98
359_R	407_E	0.778	0.98
85_F	468_Y	0.775	0.98
177_T	222_S	0.774	0.98
250_Y	256_D	0.774	0.98
341_N	344_V	0.773	0.98
319_T	352_Q	0.772	0.98
163_V	166_E	0.772	0.98
319_T	354_D	0.768	0.97
73_Y	77_I	0.767	0.97
20_A	93_A	0.767	0.97
253_N	256_D	0.766	0.97
209_E	213_Q	0.765	0.97
97_I	164_V	0.762	0.97
281_S	284_L	0.762	0.97
202_T	205_E	0.761	0.97
28_N	34_P	0.758	0.97
319_T	357_G	0.756	0.97
366_Y	417_V	0.755	0.97
106_P	111_L	0.755	0.97
81_A	125_N	0.754	0.97
215_L	269_V	0.753	0.97
177_T	238_V	0.752	0.97
362_L	419_L	0.751	0.97
65_E	68_D	0.749	0.97
7_T	409_K	0.749	0.97
194_Y	202_T	0.748	0.97
102_D	140_H	0.746	0.97
150_N	156_F	0.745	0.97
275_L	309_C	0.744	0.97
275_L	312_L	0.743	0.97
227_K	304_L	0.742	0.97
51_I	61_Y	0.741	0.97
247_L	322_V	0.740	0.97
261_Q	364_E	0.739	0.97
83_M	461_R	0.737	0.97
108_E	115_D	0.735	0.97
258_M	356_V	0.731	0.97
128_P	173_K	0.731	0.97
76_D	459_R	0.730	0.97
93_A	136_E	0.727	0.96
27_W	64_H	0.727	0.96
363_C	366_Y	0.726	0.96
11_D	475_N	0.725	0.96
237_K	372_P	0.724	0.96
371_R	418_D	0.722	0.96
445_I	461_R	0.721	0.96
373_L	417_V	0.721	0.96
353_I	382_A	0.718	0.96
63_N	66_A	0.718	0.96
110_G	113_F	0.716	0.96
169_K	232_I	0.711	0.96
23_V	430_C	0.706	0.96
26_G	70_Y	0.701	0.96
182_N	243_A	0.700	0.96
246_P	360_Y	0.700	0.96
194_Y	204_H	0.698	0.96
130_I	172_V	0.698	0.96
244_M	268_Y	0.696	0.95
149_T	214_V	0.696	0.95
405_I	471_V	0.695	0.95
30_G	70_Y	0.694	0.95
340_P	343_Y	0.693	0.95
219_F	274_Q	0.693	0.95
165_F	232_I	0.692	0.95
221_A	225_A	0.691	0.95
98_F	105_Q	0.691	0.95
18_V	428_I	0.687	0.95
411_A	417_V	0.687	0.95
471_V	474_S	0.685	0.95
151_R	220_V	0.685	0.95
283_V	287_W	0.684	0.95
72_H	457_M	0.684	0.95
34_P	42_G	0.684	0.95
100_K	144_Q	0.683	0.95
257_V	261_Q	0.681	0.95
430_C	442_Y	0.680	0.95
444_F	468_Y	0.679	0.95
206_N	209_E	0.679	0.95
348_D	382_A	0.679	0.95
102_D	159_R	0.679	0.95
63_N	436_G	0.676	0.95
122_L	173_K	0.676	0.95
121_L	124_Y	0.674	0.95
405_I	424_P	0.674	0.95
356_V	359_R	0.674	0.95
298_D	303_V	0.667	0.94
14_W	86_K	0.667	0.94
387_E	392_I	0.664	0.94
143_Q	194_Y	0.663	0.94
155_D	159_R	0.662	0.94
387_E	460_S	0.660	0.94
118_F	172_V	0.660	0.94
314_F	365_L	0.659	0.94
83_M	444_F	0.659	0.94
241_M	315_S	0.658	0.94
164_V	175_W	0.656	0.94
390_G	458_S	0.655	0.94
122_L	127_E	0.655	0.94
316_Y	358_L	0.655	0.94
300_D	304_L	0.654	0.94
242_L	270_F	0.654	0.94
244_M	271_T	0.654	0.94
398_I	463_K	0.653	0.94
198_G	205_E	0.653	0.94
391_S	460_S	0.653	0.94
86_K	127_E	0.652	0.94
42_G	47_V	0.652	0.94
162_E	231_R	0.648	0.93
77_I	126_I	0.648	0.93
34_P	139_L	0.647	0.93
121_L	125_N	0.647	0.93
432_S	442_Y	0.646	0.93
253_N	324_A	0.642	0.93
315_S	376_V	0.642	0.93
17_A	423_T	0.640	0.93
386_V	389_D	0.639	0.93
305_R	308_T	0.639	0.93
122_L	125_N	0.639	0.93
27_W	93_A	0.637	0.93
166_E	228_A	0.637	0.93
209_E	294_I	0.637	0.93
248_Y	319_T	0.636	0.93
80_F	427_C	0.636	0.93
13_L	86_K	0.635	0.93
154_V	221_A	0.633	0.93
259_F	263_S	0.633	0.93
133_S	184_Q	0.632	0.93
212_Y	287_W	0.629	0.92
100_K	104_A	0.629	0.92
161_A	164_V	0.626	0.92
159_R	163_V	0.626	0.92
90_T	121_L	0.625	0.92
391_S	466_N	0.625	0.92
288_E	293_N	0.625	0.92
374_F	421_G	0.625	0.92
325_E	328_T	0.624	0.92
129_V	176_M	0.623	0.92
395_D	398_I	0.623	0.92
74_K	78_K	0.622	0.92
11_D	412_V	0.621	0.92
101_G	141_L	0.621	0.92
362_L	411_A	0.620	0.92
457_M	461_R	0.619	0.92
194_Y	200_V	0.619	0.92
237_K	420_M	0.618	0.92
15_G	423_T	0.616	0.92
97_I	111_L	0.616	0.92
141_L	156_F	0.616	0.92
92_I	118_F	0.615	0.91
431_V	449_K	0.614	0.91
149_T	213_Q	0.613	0.91
172_V	175_W	0.613	0.91
52_T	435_T	0.612	0.91
410_K	415_D	0.611	0.91
408_M	412_V	0.611	0.91
89_R	179_N	0.609	0.91
299_G	305_R	0.609	0.91
251_S	323_K	0.607	0.91
333_S	336_E	0.604	0.91
285_N	410_K	0.603	0.91
349_W	435_T	0.603	0.91
226_V	309_C	0.603	0.91
98_F	159_R	0.602	0.91
312_L	371_R	0.602	0.91
132_L	165_F	0.602	0.91
250_Y	321_A	0.600	0.90
47_V	51_I	0.599	0.90
348_D	440_K	0.599	0.90
224_L	303_V	0.598	0.90
446_Y	462_K	0.598	0.90
244_M	365_L	0.597	0.90
157_F	178_F	0.595	0.90
86_K	472_I	0.594	0.90
41_T	431_V	0.594	0.90
198_G	203_E	0.593	0.90
79_L	428_I	0.592	0.90
227_K	308_T	0.590	0.90
111_L	168_Y	0.590	0.90
446_Y	458_S	0.588	0.90
246_P	264_M	0.587	0.90
81_A	123_K	0.587	0.90
201_Y	204_H	0.587	0.90
8_L	475_N	0.585	0.89
18_V	427_C	0.585	0.89
88_F	121_L	0.584	0.89
284_L	301_L	0.584	0.89
283_V	286_E	0.584	0.89
342_P	345_K	0.584	0.89
427_C	445_I	0.583	0.89
265_R	364_E	0.581	0.89
119_D	170_H	0.581	0.89
79_L	445_I	0.580	0.89
132_L	161_A	0.579	0.89
266_E	283_V	0.579	0.89
245_V	320_N	0.577	0.89
34_P	95_T	0.576	0.89
192_F	199_V	0.576	0.89
36_I	133_S	0.574	0.88
98_F	102_D	0.573	0.88
74_K	77_I	0.573	0.88
294_I	301_L	0.572	0.88
83_M	465_F	0.571	0.88
36_I	143_Q	0.569	0.88
376_V	420_M	0.568	0.88
269_V	287_W	0.568	0.88
334_G	338_S	0.566	0.88
119_D	123_K	0.565	0.88
223_A	308_T	0.565	0.88
8_L	14_W	0.564	0.88
41_T	47_V	0.563	0.87
248_Y	354_D	0.563	0.87
365_L	373_L	0.563	0.87
195_C	202_T	0.561	0.87
194_Y	201_Y	0.561	0.87
154_V	158_V	0.561	0.87
372_P	418_D	0.561	0.87
298_D	306_E	0.561	0.87
227_K	230_R	0.560	0.87
26_G	32_K	0.559	0.87
84_G	469_K	0.559	0.87
213_Q	217_H	0.557	0.87
232_I	236_M	0.557	0.87
239_G	374_F	0.557	0.87
431_V	438_Y	0.557	0.87
277_G	306_E	0.557	0.87
100_K	156_F	0.557	0.87
209_E	293_N	0.556	0.87
430_C	433_F	0.556	0.87
271_T	365_L	0.555	0.87
52_T	61_Y	0.555	0.87
140_H	156_F	0.555	0.87
410_K	413_T	0.553	0.87
249_P	256_D	0.553	0.87
374_F	423_T	0.551	0.86
69_F	80_F	0.551	0.86
33_G	98_F	0.550	0.86
222_S	274_Q	0.550	0.86
116_D	120_E	0.549	0.86
41_T	63_N	0.547	0.86
223_A	307_G	0.547	0.86
66_A	457_M	0.546	0.86
27_W	42_G	0.546	0.86
256_D	259_F	0.545	0.86
339_V	343_Y	0.545	0.86
129_V	420_M	0.541	0.85
23_V	88_F	0.541	0.85
140_H	143_Q	0.541	0.85
398_I	402_R	0.540	0.85
373_L	419_L	0.539	0.85
259_F	262_E	0.539	0.85
317_Y	377_E	0.537	0.85
174_Y	374_F	0.536	0.85
347_S	382_A	0.536	0.85
85_F	126_I	0.535	0.85
193_G	202_T	0.535	0.85
245_V	267_R	0.532	0.84
441_R	446_Y	0.532	0.84
18_V	69_F	0.531	0.84
272_D	278_Y	0.529	0.84
69_F	77_I	0.529	0.84
72_H	456_D	0.529	0.84
426_G	430_C	0.529	0.84
360_Y	363_C	0.528	0.84
148_W	178_F	0.527	0.84
11_D	86_K	0.527	0.84
389_D	393_N	0.526	0.84
262_E	324_A	0.526	0.84
80_F	88_F	0.525	0.84
69_F	73_Y	0.523	0.83
49_R	52_T	0.523	0.83
28_N	64_H	0.519	0.83
347_S	381_G	0.519	0.83
212_Y	290_R	0.518	0.83
65_E	71_G	0.518	0.83
401_L	405_I	0.518	0.83
32_K	136_E	0.517	0.83
450_H	458_S	0.516	0.83
193_G	197_S	0.516	0.83
271_T	275_L	0.515	0.82
21_H	41_T	0.515	0.82
177_T	225_A	0.514	0.82
141_L	153_V	0.514	0.82
18_V	430_C	0.512	0.82
332_I	335_F	0.511	0.82
145_Y	150_N	0.510	0.82
425_W	430_C	0.510	0.82
445_I	465_F	0.508	0.82
372_P	420_M	0.508	0.82
301_L	306_E	0.507	0.82
37_C	40_L	0.507	0.82
191_L	194_Y	0.506	0.81
407_E	415_D	0.505	0.81
344_V	352_Q	0.504	0.81
241_M	311_Y	0.503	0.81
194_Y	205_E	0.503	0.81
82_E	466_N	0.503	0.81
323_K	339_V	0.502	0.81
251_S	257_V	0.501	0.81
200_V	203_E	0.501	0.81
131_T	241_M	0.500	0.81
401_L	468_Y	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1v02A	2	0.9374	100	0.124	Contact Map
3ptmA	1	0.9374	100	0.125	Contact Map
2jf7A	5	0.9248	100	0.126	Contact Map
2dgaA	5	0.9436	100	0.129	Contact Map
3wq5A	1	0.9374	100	0.129	Contact Map
1v08A	2	0.9395	100	0.131	Contact Map
1cbgA	2	0.9395	100	0.132	Contact Map
3f5lA	2	0.9332	100	0.134	Contact Map
4f66A	2	0.9833	100	0.139	Contact Map
4iplA	2	0.9436	100	0.143	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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