UACT - ECOLI - GREMLIN Contacts

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UACT - Uric acid transporter UacT

UniProt:	Q46821	Sequences: MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVCISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13071
Length:	482 (406)
Sequences:	4386 (2233)
Seq/√Len:	110.8

ECOLI - UACT XANQ XANP YBBY URAA RUTG
BACSU - PBUX PUCJ PUCK YWDJ PYRP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
126_I	306_G	5.043	1.00
194_F	217_F	5.035	1.00
190_A	221_L	5.019	1.00
170_A	188_S	4.103	1.00
157_S	431_A	3.957	1.00
195_I	214_G	3.839	1.00
220_L	224_M	3.509	1.00
131_I	261_T	3.481	1.00
72_F	345_G	3.461	1.00
231_S	235_D	3.418	1.00
238_W	349_K	3.301	1.00
402_V	434_S	3.092	1.00
198_I	213_L	3.060	1.00
187_I	222_S	3.058	1.00
123_G	252_F	2.749	1.00
75_G	342_I	2.691	1.00
230_L	233_L	2.671	1.00
190_A	217_F	2.655	1.00
399_S	435_A	2.646	1.00
187_I	227_E	2.628	1.00
119_L	251_I	2.626	1.00
245_M	307_T	2.561	1.00
236_A	349_K	2.465	1.00
120_G	251_I	2.444	1.00
192_L	368_V	2.403	1.00
275_F	294_G	2.359	1.00
34_G	336_S	2.325	1.00
390_R	443_N	2.322	1.00
38_V	340_I	2.318	1.00
77_V	301_G	2.275	1.00
126_I	303_M	2.273	1.00
92_R	288_S	2.272	1.00
127_A	257_I	2.224	1.00
187_I	225_M	2.224	1.00
216_V	220_L	2.209	1.00
31_I	340_I	2.192	1.00
30_L	336_S	2.181	1.00
117_G	120_G	2.155	1.00
186_G	190_A	2.132	1.00
190_A	194_F	2.128	1.00
220_L	223_W	2.087	1.00
233_L	353_L	2.082	1.00
234_H	237_S	2.082	1.00
133_T	303_M	2.074	1.00
73_C	308_F	2.068	1.00
79_L	338_G	2.054	1.00
130_F	134_L	2.025	1.00
79_L	335_I	2.015	1.00
145_L	440_V	2.003	1.00
194_F	221_L	1.998	1.00
133_T	296_R	1.994	1.00
136_A	296_R	1.978	1.00
194_F	198_I	1.969	1.00
183_V	227_E	1.937	1.00
82_C	335_I	1.917	1.00
437_V	441_F	1.890	1.00
219_F	228_V	1.888	1.00
328_V	333_V	1.864	1.00
52_I	107_M	1.864	1.00
232_G	356_S	1.859	1.00
107_M	121_I	1.849	1.00
130_F	303_M	1.821	1.00
135_L	268_F	1.817	1.00
198_I	202_A	1.811	1.00
129_G	303_M	1.807	1.00
182_P	186_G	1.800	1.00
125_T	306_G	1.791	1.00
219_F	356_S	1.783	1.00
116_I	253_D	1.779	1.00
72_F	342_I	1.770	1.00
231_S	234_H	1.768	1.00
22_D	284_R	1.760	1.00
195_I	365_A	1.733	1.00
279_G	286_L	1.712	1.00
160_L	374_L	1.711	1.00
197_L	201_Y	1.709	1.00
221_L	225_M	1.709	1.00
147_P	439_N	1.698	1.00
169_W	359_Q	1.667	1.00
282_V	285_K	1.656	1.00
339_I	343_L	1.653	1.00
236_A	352_V	1.648	1.00
233_L	236_A	1.592	1.00
53_G	58_L	1.585	1.00
253_D	256_S	1.577	1.00
38_V	337_S	1.572	1.00
287_S	290_D	1.571	1.00
133_T	299_G	1.564	1.00
186_G	189_F	1.556	1.00
205_F	209_V	1.547	1.00
192_L	398_I	1.540	1.00
399_S	434_S	1.528	1.00
108_I	111_G	1.493	1.00
202_A	206_M	1.488	1.00
74_C	96_I	1.481	1.00
24_I	332_W	1.466	1.00
189_F	193_I	1.460	1.00
395_I	438_L	1.456	1.00
244_P	309_N	1.451	1.00
221_L	224_M	1.448	1.00
133_T	300_V	1.447	1.00
183_V	225_M	1.428	1.00
149_L	396_V	1.413	1.00
244_P	307_T	1.408	1.00
218_G	361_V	1.407	1.00
402_V	430_L	1.372	1.00
284_R	290_D	1.360	1.00
79_L	82_C	1.358	1.00
223_W	230_L	1.346	1.00
224_M	227_E	1.342	1.00
245_M	248_G	1.342	1.00
129_G	302_T	1.336	1.00
120_G	253_D	1.332	1.00
290_D	293_R	1.332	1.00
206_M	213_L	1.330	1.00
433_L	437_V	1.317	0.99
232_G	235_D	1.316	0.99
246_S	309_N	1.315	0.99
421_Q	425_H	1.303	0.99
76_I	342_I	1.295	0.99
37_H	319_N	1.292	0.99
20_E	23_R	1.285	0.99
134_L	138_L	1.284	0.99
245_M	250_P	1.279	0.99
110_I	256_S	1.272	0.99
280_E	383_R	1.270	0.99
79_L	342_I	1.266	0.99
398_I	434_S	1.263	0.99
171_A	179_Y	1.261	0.99
418_A	421_Q	1.258	0.99
104_V	108_I	1.255	0.99
83_I	335_I	1.251	0.99
41_M	45_A	1.245	0.99
19_D	23_R	1.242	0.99
82_C	334_C	1.237	0.99
349_K	352_V	1.234	0.99
202_A	207_S	1.231	0.99
209_V	213_L	1.228	0.99
20_E	284_R	1.228	0.99
28_G	32_I	1.215	0.99
217_F	221_L	1.212	0.99
78_T	96_I	1.211	0.99
126_I	250_P	1.205	0.99
384_C	392_N	1.204	0.99
178_Q	181_N	1.201	0.99
278_L	323_V	1.201	0.99
323_V	329_H	1.197	0.99
274_M	317_S	1.182	0.99
213_L	217_F	1.182	0.99
72_F	308_F	1.169	0.99
95_V	278_L	1.167	0.99
252_F	257_I	1.162	0.99
129_G	299_G	1.162	0.99
149_L	153_V	1.155	0.99
100_T	267_V	1.140	0.99
254_P	257_I	1.138	0.99
157_S	403_G	1.133	0.98
167_I	405_T	1.130	0.98
193_I	197_L	1.121	0.98
420_L	423_L	1.121	0.98
386_Y	396_V	1.113	0.98
116_I	256_S	1.113	0.98
400_L	404_M	1.108	0.98
347_V	351_A	1.093	0.98
172_G	179_Y	1.089	0.98
132_T	267_V	1.082	0.98
89_M	300_V	1.081	0.98
116_I	120_G	1.079	0.98
240_A	348_P	1.077	0.98
102_A	267_V	1.075	0.98
183_V	186_G	1.075	0.98
98_S	316_F	1.072	0.98
126_I	307_T	1.070	0.98
190_A	225_M	1.060	0.98
223_W	228_V	1.051	0.98
27_P	31_I	1.049	0.97
60_K	67_I	1.047	0.97
128_A	264_L	1.045	0.97
271_S	275_F	1.038	0.97
186_G	225_M	1.031	0.97
97_M	315_S	1.025	0.97
270_E	314_T	1.021	0.97
25_L	330_S	1.021	0.97
343_L	347_V	1.018	0.97
110_I	260_M	1.017	0.97
106_P	263_V	1.014	0.97
19_D	25_L	1.014	0.97
111_G	121_I	0.998	0.97
275_F	298_D	0.997	0.97
394_Y	398_I	0.997	0.97
31_I	35_L	0.991	0.96
274_M	320_V	0.987	0.96
90_G	293_R	0.983	0.96
305_G	313_H	0.983	0.96
183_V	187_I	0.981	0.96
40_V	322_L	0.963	0.96
420_L	424_L	0.960	0.96
222_S	227_E	0.959	0.96
96_I	337_S	0.956	0.96
95_V	315_S	0.956	0.96
156_T	400_L	0.950	0.95
197_L	441_F	0.945	0.95
76_I	80_L	0.939	0.95
25_L	333_V	0.938	0.95
48_V	101_F	0.938	0.95
76_I	304_I	0.935	0.95
123_G	127_A	0.935	0.95
203_K	207_S	0.932	0.95
181_N	184_Y	0.927	0.95
25_L	30_L	0.924	0.95
136_A	292_I	0.924	0.95
271_S	294_G	0.922	0.95
176_N	184_Y	0.922	0.95
304_I	308_F	0.918	0.95
24_I	30_L	0.917	0.95
222_S	226_N	0.917	0.95
50_L	67_I	0.902	0.94
249_M	307_T	0.900	0.94
332_W	335_I	0.894	0.94
35_L	340_I	0.890	0.94
21_V	24_I	0.890	0.94
26_S	29_K	0.887	0.94
168_D	179_Y	0.885	0.93
243_T	246_S	0.882	0.93
412_F	417_P	0.877	0.93
255_V	259_T	0.869	0.93
100_T	314_T	0.866	0.93
163_I	401_G	0.866	0.93
146_F	432_T	0.866	0.93
176_N	181_N	0.862	0.93
124_A	256_S	0.861	0.92
254_P	258_L	0.857	0.92
335_I	338_G	0.856	0.92
37_H	41_M	0.855	0.92
75_G	338_G	0.855	0.92
172_G	180_G	0.855	0.92
79_L	339_I	0.854	0.92
37_H	40_V	0.853	0.92
184_Y	360_F	0.851	0.92
375_A	393_L	0.848	0.92
166_G	191_V	0.847	0.92
229_N	232_G	0.846	0.92
230_L	356_S	0.846	0.92
156_T	378_I	0.844	0.92
350_M	353_L	0.841	0.92
187_I	221_L	0.840	0.92
282_V	329_H	0.835	0.91
374_L	400_L	0.835	0.91
219_F	230_L	0.833	0.91
179_Y	409_S	0.830	0.91
136_A	299_G	0.829	0.91
140_G	292_I	0.827	0.91
219_F	357_I	0.826	0.91
289_H	293_R	0.825	0.91
96_I	334_C	0.823	0.91
73_C	310_S	0.821	0.91
176_N	179_Y	0.820	0.91
31_I	336_S	0.816	0.90
119_L	248_G	0.816	0.90
171_A	412_F	0.813	0.90
81_Q	93_L	0.812	0.90
139_I	295_L	0.812	0.90
387_T	392_N	0.812	0.90
95_V	275_F	0.811	0.90
161_S	428_I	0.806	0.90
119_L	250_P	0.803	0.90
212_L	216_V	0.803	0.90
110_I	124_A	0.801	0.89
241_I	346_M	0.800	0.89
133_T	137_P	0.799	0.89
247_F	250_P	0.798	0.89
326_T	340_I	0.796	0.89
109_A	112_M	0.794	0.89
368_V	394_Y	0.794	0.89
124_A	128_A	0.792	0.89
220_L	343_L	0.791	0.89
132_T	299_G	0.790	0.89
193_I	196_L	0.789	0.89
267_V	314_T	0.788	0.89
300_V	304_I	0.788	0.89
120_G	256_S	0.787	0.89
31_I	234_H	0.785	0.89
50_L	53_G	0.781	0.88
189_F	225_M	0.780	0.88
344_F	350_M	0.777	0.88
238_W	242_V	0.775	0.88
95_V	322_L	0.774	0.88
238_W	347_V	0.774	0.88
403_G	431_A	0.770	0.88
73_C	304_I	0.767	0.87
192_L	196_L	0.766	0.87
19_D	26_S	0.766	0.87
335_I	339_I	0.765	0.87
82_C	331_R	0.765	0.87
169_W	370_F	0.762	0.87
198_I	214_G	0.759	0.87
233_L	349_K	0.759	0.87
265_I	269_I	0.759	0.87
170_A	367_L	0.758	0.87
237_S	240_A	0.757	0.87
44_G	318_Q	0.756	0.87
102_A	369_M	0.756	0.87
166_G	188_S	0.755	0.87
198_I	206_M	0.754	0.86
48_V	99_V	0.753	0.86
169_W	362_L	0.752	0.86
233_L	356_S	0.751	0.86
320_V	323_V	0.750	0.86
171_A	180_G	0.747	0.86
153_V	399_S	0.747	0.86
155_I	274_M	0.744	0.86
179_Y	182_P	0.744	0.86
395_I	443_N	0.742	0.86
168_D	171_A	0.741	0.86
104_V	265_I	0.739	0.85
271_S	298_D	0.739	0.85
50_L	362_L	0.737	0.85
187_I	360_F	0.736	0.85
233_L	352_V	0.736	0.85
406_P	430_L	0.736	0.85
99_V	103_A	0.736	0.85
145_L	436_V	0.736	0.85
214_G	217_F	0.735	0.85
184_Y	227_E	0.734	0.85
194_F	214_G	0.733	0.85
398_I	438_L	0.733	0.85
44_G	370_F	0.726	0.84
197_L	202_A	0.726	0.84
199_T	325_V	0.725	0.84
45_A	74_C	0.723	0.84
156_T	381_L	0.722	0.84
198_I	217_F	0.721	0.84
250_P	253_D	0.721	0.84
200_R	373_V	0.721	0.84
126_I	130_F	0.719	0.84
94_P	334_C	0.718	0.84
265_I	277_A	0.717	0.84
390_R	395_I	0.714	0.83
27_P	340_I	0.714	0.83
105_T	108_I	0.713	0.83
126_I	252_F	0.712	0.83
302_T	313_H	0.704	0.82
41_M	319_N	0.701	0.82
199_T	394_Y	0.701	0.82
271_S	314_T	0.699	0.82
69_S	72_F	0.697	0.82
427_G	431_A	0.696	0.82
33_L	37_H	0.696	0.82
127_A	252_F	0.696	0.82
120_G	124_A	0.695	0.82
41_M	96_I	0.694	0.82
371_G	375_A	0.692	0.81
119_L	122_F	0.692	0.81
176_N	180_G	0.689	0.81
215_I	365_A	0.688	0.81
34_G	337_S	0.688	0.81
93_L	294_G	0.688	0.81
70_D	311_F	0.686	0.81
278_L	320_V	0.686	0.81
340_I	344_F	0.686	0.81
397_A	401_G	0.685	0.81
241_I	345_G	0.683	0.81
132_T	264_L	0.682	0.80
80_L	297_V	0.681	0.80
38_V	344_F	0.681	0.80
100_T	103_A	0.681	0.80
278_L	315_S	0.680	0.80
395_I	399_S	0.680	0.80
68_S	351_A	0.679	0.80
402_V	406_P	0.678	0.80
70_D	74_C	0.677	0.80
211_V	322_L	0.676	0.80
107_M	125_T	0.675	0.80
194_F	213_L	0.675	0.80
217_F	220_L	0.675	0.80
168_D	176_N	0.675	0.80
215_I	269_I	0.675	0.80
155_I	158_I	0.673	0.80
272_M	291_I	0.673	0.80
47_A	169_W	0.671	0.79
222_S	225_M	0.669	0.79
73_C	305_G	0.665	0.79
43_A	49_P	0.662	0.78
52_I	215_I	0.662	0.78
94_P	124_A	0.661	0.78
102_A	158_I	0.658	0.78
70_D	99_V	0.657	0.78
149_L	392_N	0.655	0.78
375_A	396_V	0.655	0.78
141_R	288_S	0.653	0.78
171_A	185_L	0.653	0.78
69_S	73_C	0.652	0.77
225_M	350_M	0.651	0.77
41_M	379_R	0.651	0.77
187_I	361_V	0.650	0.77
396_V	400_L	0.649	0.77
405_T	412_F	0.649	0.77
111_G	116_I	0.648	0.77
97_M	271_S	0.647	0.77
386_Y	392_N	0.646	0.77
126_I	249_M	0.644	0.77
261_T	264_L	0.642	0.76
352_V	356_S	0.641	0.76
204_G	214_G	0.641	0.76
45_A	70_D	0.641	0.76
161_S	426_S	0.640	0.76
216_V	441_F	0.637	0.76
215_I	362_L	0.635	0.76
186_G	221_L	0.633	0.75
72_F	346_M	0.632	0.75
141_R	145_L	0.632	0.75
45_A	48_V	0.632	0.75
317_S	376_T	0.630	0.75
200_R	375_A	0.629	0.75
193_I	216_V	0.628	0.75
102_A	314_T	0.626	0.75
108_I	112_M	0.626	0.75
267_V	270_E	0.624	0.74
105_T	109_A	0.623	0.74
185_L	189_F	0.622	0.74
73_C	301_G	0.620	0.74
270_E	298_D	0.620	0.74
208_N	443_N	0.619	0.74
352_V	355_A	0.619	0.74
324_S	379_R	0.618	0.74
21_V	25_L	0.617	0.73
144_P	440_V	0.617	0.73
339_I	383_R	0.615	0.73
109_A	115_D	0.615	0.73
76_I	308_F	0.614	0.73
195_I	368_V	0.614	0.73
34_G	155_I	0.613	0.73
195_I	378_I	0.613	0.73
165_V	169_W	0.612	0.73
401_G	404_M	0.611	0.73
130_F	133_T	0.611	0.73
132_T	268_F	0.610	0.73
135_L	138_L	0.608	0.72
141_R	146_F	0.607	0.72
381_L	384_C	0.607	0.72
163_I	404_M	0.604	0.72
442_F	445_Y	0.601	0.72
37_H	322_L	0.601	0.72
23_R	330_S	0.600	0.71
140_G	144_P	0.597	0.71
386_Y	393_L	0.596	0.71
416_L	421_Q	0.595	0.71
302_T	305_G	0.595	0.71
149_L	395_I	0.594	0.71
213_L	216_V	0.593	0.70
107_M	260_M	0.591	0.70
281_I	324_S	0.591	0.70
286_L	290_D	0.591	0.70
195_I	198_I	0.591	0.70
111_G	117_G	0.591	0.70
431_A	435_A	0.591	0.70
78_T	338_G	0.590	0.70
239_F	347_V	0.586	0.70
403_G	427_G	0.586	0.70
303_M	307_T	0.586	0.70
45_A	341_L	0.586	0.70
283_G	329_H	0.585	0.69
260_M	360_F	0.585	0.69
419_V	422_P	0.585	0.69
124_A	257_I	0.584	0.69
345_G	351_A	0.584	0.69
202_A	205_F	0.583	0.69
198_I	210_A	0.583	0.69
223_W	226_N	0.582	0.69
228_V	356_S	0.582	0.69
97_M	302_T	0.580	0.69
317_S	429_M	0.580	0.69
91_I	290_D	0.579	0.69
118_L	122_F	0.578	0.69
112_M	115_D	0.578	0.69
271_S	315_S	0.578	0.69
35_L	171_A	0.577	0.68
374_L	378_I	0.577	0.68
324_S	367_L	0.576	0.68
298_D	397_A	0.574	0.68
156_T	374_L	0.574	0.68
153_V	435_A	0.574	0.68
274_M	315_S	0.574	0.68
388_T	446_Q	0.574	0.68
216_V	353_L	0.573	0.68
94_P	282_V	0.573	0.68
187_I	215_I	0.572	0.68
206_M	210_A	0.572	0.68
74_C	95_V	0.570	0.67
274_M	376_T	0.570	0.67
152_G	377_G	0.570	0.67
379_R	386_Y	0.568	0.67
218_G	226_N	0.568	0.67
110_I	123_G	0.566	0.67
99_V	166_G	0.566	0.67
110_I	121_I	0.565	0.67
241_I	265_I	0.565	0.67
318_Q	370_F	0.565	0.67
379_R	383_R	0.564	0.67
147_P	321_G	0.564	0.67
277_A	376_T	0.563	0.67
156_T	195_I	0.563	0.67
169_W	366_G	0.561	0.66
147_P	152_G	0.560	0.66
259_T	423_L	0.560	0.66
168_D	216_V	0.560	0.66
151_T	348_P	0.559	0.66
272_M	276_L	0.559	0.66
273_G	403_G	0.559	0.66
75_G	326_T	0.557	0.66
158_I	316_F	0.555	0.65
267_V	275_F	0.554	0.65
241_I	244_P	0.554	0.65
122_F	126_I	0.554	0.65
146_F	204_G	0.554	0.65
33_L	317_S	0.553	0.65
264_L	302_T	0.553	0.65
33_L	146_F	0.551	0.65
303_M	306_G	0.551	0.65
80_L	133_T	0.550	0.65
46_V	67_I	0.549	0.65
77_V	297_V	0.549	0.65
317_S	320_V	0.546	0.64
224_M	241_I	0.546	0.64
220_L	234_H	0.545	0.64
163_I	397_A	0.545	0.64
49_P	53_G	0.545	0.64
111_G	348_P	0.543	0.64
236_A	348_P	0.543	0.64
232_G	308_F	0.542	0.64
127_A	261_T	0.541	0.63
362_L	365_A	0.540	0.63
103_A	302_T	0.540	0.63
161_S	427_G	0.540	0.63
154_V	192_L	0.538	0.63
75_G	79_L	0.538	0.63
89_M	293_R	0.538	0.63
191_V	375_A	0.537	0.63
69_S	309_N	0.536	0.63
230_L	353_L	0.536	0.63
436_V	440_V	0.535	0.63
47_A	50_L	0.535	0.63
72_F	425_H	0.535	0.63
371_G	393_L	0.534	0.63
19_D	22_D	0.533	0.62
148_P	393_L	0.532	0.62
328_V	362_L	0.532	0.62
331_R	335_I	0.532	0.62
132_T	431_A	0.530	0.62
381_L	386_Y	0.529	0.62
169_W	363_G	0.528	0.62
99_V	314_T	0.528	0.62
124_A	261_T	0.528	0.62
38_V	260_M	0.528	0.62
24_I	27_P	0.527	0.61
79_L	330_S	0.527	0.61
97_M	274_M	0.527	0.61
298_D	314_T	0.527	0.61
58_L	311_F	0.526	0.61
27_P	30_L	0.526	0.61
385_N	392_N	0.523	0.61
185_L	412_F	0.523	0.61
74_C	263_V	0.523	0.61
318_Q	372_M	0.523	0.61
97_M	275_F	0.521	0.61
197_L	437_V	0.520	0.60
276_L	327_R	0.520	0.60
159_G	166_G	0.520	0.60
33_L	372_M	0.520	0.60
99_V	274_M	0.519	0.60
135_L	389_N	0.519	0.60
21_V	330_S	0.517	0.60
184_Y	187_I	0.517	0.60
130_F	181_N	0.517	0.60
39_L	395_I	0.517	0.60
275_F	286_L	0.516	0.60
375_A	397_A	0.516	0.60
58_L	111_G	0.516	0.60
47_A	51_M	0.514	0.60
199_T	207_S	0.514	0.60
169_W	188_S	0.514	0.60
81_Q	331_R	0.513	0.59
123_G	250_P	0.513	0.59
78_T	314_T	0.512	0.59
217_F	224_M	0.512	0.59
223_W	408_L	0.511	0.59
163_I	367_L	0.511	0.59
376_T	379_R	0.510	0.59
231_S	236_A	0.510	0.59
319_N	322_L	0.510	0.59
191_V	309_N	0.510	0.59
193_I	418_A	0.509	0.59
25_L	332_W	0.509	0.59
30_L	332_W	0.508	0.59
185_L	407_T	0.508	0.59
402_V	407_T	0.508	0.59
45_A	99_V	0.508	0.59
159_G	374_L	0.507	0.59
46_V	354_V	0.506	0.58
146_F	151_T	0.505	0.58
294_G	298_D	0.505	0.58
429_M	433_L	0.503	0.58
300_V	303_M	0.503	0.58
27_P	339_I	0.503	0.58
82_C	338_G	0.503	0.58
43_A	318_Q	0.502	0.58
340_I	433_L	0.501	0.58
278_L	354_V	0.500	0.58
219_F	223_W	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qe7A	2	0.8257	100	0.444	Contact Map
3wdoA	1	0.8506	97.5	0.937	Contact Map
4pypA	1	0.8257	97	0.942	Contact Map
4m64A	1	0.8008	96.5	0.946	Contact Map
4zw9A	1	0.8568	96.4	0.947	Contact Map
2jlnA	1	0.8071	95.9	0.949	Contact Map
1pw4A	1	0.8465	95.9	0.949	Contact Map
4j05A	3	0.7884	94	0.954	Contact Map
4tphA	2	0.7884	93.8	0.955	Contact Map
4ikvA	1	0.8589	93.4	0.955	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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