XDHD - ECOLI - GREMLIN Contacts

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XDHD - Probable hypoxanthine oxidase XdhD

UniProt:	Q46814	Sequences: MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFAGSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATIDIAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHLDVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVVAESEEIALEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNSHAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCPTETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQDILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDFRANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNFAITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEILRQGREMIQWSSPKPQNGDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSGGADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARLAAENLREKILFHGAQMLGEPVADVQLATPGVVRGKKGEVSFGDIAHKGETGTGFGSLVGTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGATLRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKSISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13064
Length:	956 (737)
Sequences:	4686 (3064)
Seq/√Len:	112.8

ECOLI - XDHD XDHA YAGR
BACSU - XDHD
SULSO - Q7LX54 Q97VI4 Q97V74 Q97UK2 Q97TZ2 Q7LXA2 Q97YU6 Q97UR0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
226_L	289_L	5.032	1.00
206_L	290_I	4.754	1.00
380_E	492_K	4.627	1.00
279_S	282_I	4.206	1.00
222_K	291_D	4.074	1.00
201_C	230_V	4.033	1.00
382_T	490_T	3.869	1.00
625_L	628_G	3.854	1.00
210_H	213_A	3.758	1.00
588_E	618_S	3.659	1.00
496_K	500_R	3.520	1.00
376_D	496_K	3.510	1.00
495_A	575_L	3.492	1.00
505_K	540_D	3.480	1.00
376_D	497_K	3.443	1.00
226_L	282_I	3.426	1.00
214_L	295_E	3.406	1.00
370_K	374_D	3.388	1.00
206_L	287_L	3.328	1.00
367_D	370_K	3.297	1.00
581_I	589_R	3.297	1.00
216_T	293_E	3.211	1.00
698_A	738_A	3.204	1.00
501_L	572_L	3.165	1.00
213_A	294_Y	3.135	1.00
677_F	704_C	3.100	1.00
507_D	542_Q	2.993	1.00
276_V	460_A	2.992	1.00
210_H	296_V	2.977	1.00
535_P	596_Q	2.933	1.00
230_V	278_E	2.925	1.00
380_E	490_T	2.909	1.00
701_V	743_E	2.864	1.00
212_H	297_L	2.803	1.00
832_K	897_R	2.713	1.00
492_K	505_K	2.668	1.00
770_G	778_E	2.659	1.00
585_E	589_R	2.658	1.00
217_H	293_E	2.618	1.00
739_R	743_E	2.560	1.00
581_I	586_I	2.498	1.00
278_E	466_R	2.489	1.00
304_D	488_K	2.440	1.00
372_F	494_G	2.431	1.00
409_I	423_V	2.411	1.00
278_E	282_I	2.389	1.00
408_V	437_I	2.389	1.00
500_R	589_R	2.382	1.00
931_I	944_F	2.363	1.00
220_V	224_E	2.353	1.00
507_D	544_T	2.320	1.00
406_R	717_D	2.314	1.00
624_I	816_F	2.283	1.00
216_T	295_E	2.268	1.00
203_I	470_F	2.265	1.00
511_N	550_I	2.251	1.00
941_E	948_K	2.224	1.00
305_E	308_A	2.185	1.00
928_A	944_F	2.183	1.00
435_H	715_D	2.174	1.00
493_L	571_A	2.168	1.00
377_V	495_A	2.164	1.00
780_S	783_D	2.154	1.00
585_E	588_E	2.094	1.00
820_A	831_D	2.071	1.00
588_E	621_L	2.070	1.00
401_R	410_H	2.054	1.00
856_T	896_F	2.053	1.00
375_A	494_G	2.044	1.00
620_A	816_F	2.042	1.00
203_I	274_A	2.006	1.00
491_V	571_A	1.994	1.00
193_E	469_L	1.992	1.00
593_H	596_Q	1.991	1.00
857_L	892_I	1.988	1.00
671_L	745_L	1.986	1.00
619_C	899_V	1.978	1.00
746_R	750_L	1.974	1.00
669_I	679_V	1.966	1.00
676_T	708_D	1.964	1.00
377_V	497_K	1.959	1.00
222_K	289_L	1.954	1.00
209_P	272_V	1.951	1.00
817_A	926_A	1.939	1.00
500_R	535_P	1.922	1.00
364_H	540_D	1.910	1.00
619_C	622_E	1.902	1.00
219_D	291_D	1.888	1.00
214_L	264_K	1.884	1.00
584_L	621_L	1.882	1.00
618_S	622_E	1.865	1.00
221_S	224_E	1.857	1.00
203_I	468_V	1.853	1.00
841_T	902_P	1.848	1.00
397_I	471_R	1.839	1.00
731_T	843_V	1.838	1.00
593_H	614_P	1.828	1.00
210_H	294_Y	1.822	1.00
575_L	586_I	1.820	1.00
274_A	460_A	1.815	1.00
695_T	711_V	1.810	1.00
277_A	283_A	1.807	1.00
229_V	277_A	1.800	1.00
220_V	232_V	1.783	1.00
214_L	263_K	1.773	1.00
677_F	702_L	1.752	1.00
384_N	941_E	1.745	1.00
176_Y	706_P	1.741	1.00
230_V	466_R	1.737	1.00
392_P	447_S	1.731	1.00
226_L	286_A	1.730	1.00
760_P	763_D	1.726	1.00
212_H	264_K	1.723	1.00
493_L	575_L	1.715	1.00
391_C	881_L	1.715	1.00
222_K	225_A	1.714	1.00
302_S	305_E	1.710	1.00
287_L	290_I	1.696	1.00
372_F	492_K	1.689	1.00
828_I	949_I	1.689	1.00
705_P	708_D	1.681	1.00
842_P	900_L	1.680	1.00
375_A	502_T	1.677	1.00
621_L	627_Q	1.674	1.00
848_A	915_I	1.656	1.00
672_E	678_I	1.655	1.00
197_T	200_A	1.649	1.00
701_V	910_F	1.632	1.00
679_V	698_A	1.616	1.00
276_V	464_T	1.614	1.00
496_K	502_T	1.614	1.00
231_H	463_V	1.610	1.00
815_N	833_F	1.595	1.00
848_A	900_L	1.591	1.00
377_V	578_Q	1.586	1.00
623_E	897_R	1.578	1.00
377_V	496_K	1.575	1.00
192_V	397_I	1.571	1.00
378_I	492_K	1.568	1.00
200_A	469_L	1.567	1.00
697_L	735_G	1.556	1.00
223_A	290_I	1.552	1.00
750_L	764_V	1.551	1.00
369_D	373_A	1.537	1.00
676_T	710_H	1.536	1.00
408_V	435_H	1.525	1.00
490_T	507_D	1.523	1.00
205_M	470_F	1.521	1.00
573_A	929_T	1.513	1.00
429_M	434_V	1.507	1.00
264_K	316_D	1.502	1.00
236_L	263_K	1.496	1.00
764_V	771_V	1.493	1.00
382_T	488_K	1.493	1.00
669_I	742_A	1.490	1.00
667_C	738_A	1.488	1.00
833_F	856_T	1.487	1.00
377_V	579_L	1.486	1.00
817_A	833_F	1.478	1.00
423_V	434_V	1.475	1.00
614_P	618_S	1.470	1.00
620_A	814_A	1.468	1.00
498_D	589_R	1.464	1.00
512_T	519_S	1.460	1.00
371_G	503_A	1.457	1.00
368_M	372_F	1.455	1.00
619_C	623_E	1.454	1.00
215_I	218_L	1.453	1.00
197_T	401_R	1.448	1.00
224_E	231_H	1.444	1.00
672_E	676_T	1.442	1.00
569_T	587_I	1.432	1.00
189_P	440_R	1.419	1.00
699_A	709_V	1.416	1.00
945_T	948_K	1.411	1.00
859_A	923_A	1.410	1.00
751_F	761_V	1.407	1.00
377_V	575_L	1.406	1.00
381_R	574_E	1.405	1.00
407_L	429_M	1.405	1.00
285_E	289_L	1.397	1.00
384_N	488_K	1.395	1.00
644_W	820_A	1.395	1.00
486_V	511_N	1.395	1.00
701_V	739_R	1.392	1.00
372_F	503_A	1.388	1.00
694_V	738_A	1.388	1.00
623_E	899_V	1.385	1.00
612_S	615_S	1.378	1.00
212_H	298_K	1.377	1.00
616_A	814_A	1.368	1.00
372_F	378_I	1.365	1.00
740_L	744_N	1.360	1.00
406_R	433_K	1.359	1.00
842_P	848_A	1.349	1.00
579_L	586_I	1.342	1.00
697_L	731_T	1.336	1.00
235_H	262_G	1.332	1.00
371_G	538_N	1.325	1.00
556_Y	858_R	1.324	1.00
233_I	460_A	1.321	1.00
424_A	434_V	1.319	1.00
460_A	468_V	1.311	1.00
577_E	933_D	1.304	0.99
495_A	579_L	1.300	0.99
400_T	457_C	1.297	0.99
753_G	784_I	1.296	0.99
693_V	731_T	1.294	0.99
400_T	409_I	1.293	0.99
830_L	860_I	1.291	0.99
828_I	864_M	1.290	0.99
400_T	461_T	1.288	0.99
391_C	886_A	1.285	0.99
201_C	466_R	1.285	0.99
744_N	747_E	1.283	0.99
369_D	540_D	1.283	0.99
313_V	320_V	1.279	0.99
624_I	834_Y	1.276	0.99
501_L	536_C	1.274	0.99
193_E	471_R	1.268	0.99
577_E	932_H	1.262	0.99
772_V	775_K	1.261	0.99
591_R	617_A	1.260	0.99
215_I	292_V	1.258	0.99
489_V	567_A	1.256	0.99
369_D	505_K	1.254	0.99
493_L	501_L	1.251	0.99
821_V	828_I	1.249	0.99
509_R	544_T	1.248	0.99
303_I	509_R	1.247	0.99
631_M	635_S	1.244	0.99
819_V	931_I	1.241	0.99
204_K	287_L	1.240	0.99
839_C	842_P	1.240	0.99
585_E	627_Q	1.236	0.99
834_Y	897_R	1.235	0.99
573_A	583_Q	1.235	0.99
588_E	614_P	1.230	0.99
566_F	928_A	1.220	0.99
759_E	763_D	1.217	0.99
282_I	286_A	1.214	0.99
482_T	554_G	1.212	0.99
407_L	458_A	1.206	0.99
869_I	878_T	1.202	0.99
307_M	546_Y	1.198	0.99
828_I	931_I	1.193	0.99
214_L	297_L	1.192	0.99
368_M	371_G	1.189	0.99
430_K	433_K	1.184	0.99
233_I	464_T	1.184	0.99
495_A	586_I	1.181	0.99
197_T	399_F	1.181	0.99
217_H	291_D	1.178	0.99
315_H	547_Y	1.176	0.99
204_K	280_E	1.175	0.99
229_V	283_A	1.175	0.99
852_I	856_T	1.175	0.99
750_L	766_L	1.174	0.99
204_K	284_L	1.173	0.99
266_R	270_D	1.172	0.99
574_E	940_R	1.172	0.99
817_A	927_I	1.169	0.99
179_T	695_T	1.165	0.99
370_K	373_A	1.164	0.99
623_E	836_L	1.161	0.99
201_C	464_T	1.157	0.99
836_L	899_V	1.152	0.99
947_E	951_T	1.149	0.99
616_A	836_L	1.148	0.99
736_N	739_R	1.145	0.99
207_R	476_E	1.143	0.99
708_D	769_P	1.143	0.99
264_K	297_L	1.140	0.99
272_V	294_Y	1.140	0.99
572_L	586_I	1.136	0.99
870_Y	876_P	1.131	0.99
421_R	431_Q	1.129	0.99
620_A	836_L	1.129	0.99
695_T	706_P	1.122	0.98
622_E	627_Q	1.120	0.98
630_E	633_Q	1.118	0.98
233_I	463_V	1.116	0.98
494_G	502_T	1.111	0.98
493_L	504_V	1.106	0.98
204_K	283_A	1.106	0.98
698_A	742_A	1.106	0.98
182_A	186_Q	1.103	0.98
200_A	399_F	1.101	0.98
797_L	803_Y	1.095	0.98
826_G	949_I	1.091	0.98
196_V	200_A	1.088	0.98
645_H	823_T	1.087	0.98
233_I	276_V	1.086	0.98
452_L	455_E	1.082	0.98
817_A	830_L	1.082	0.98
273_A	292_V	1.082	0.98
213_A	292_V	1.081	0.98
379_I	495_A	1.079	0.98
584_L	650_V	1.072	0.98
230_V	282_I	1.071	0.98
372_F	505_K	1.070	0.98
865_S	891_D	1.069	0.98
410_H	437_I	1.069	0.98
398_C	457_C	1.068	0.98
234_T	260_M	1.066	0.98
864_M	927_I	1.063	0.98
752_H	788_G	1.060	0.98
177_P	846_E	1.059	0.98
238_C	459_W	1.057	0.98
307_M	509_R	1.056	0.98
280_E	284_L	1.056	0.98
441_V	686_I	1.053	0.98
304_D	382_T	1.053	0.98
523_P	543_V	1.046	0.98
171_V	700_E	1.045	0.98
402_M	462_C	1.045	0.98
383_Y	571_A	1.044	0.98
644_W	823_T	1.042	0.98
381_R	578_Q	1.042	0.98
871_D	875_H	1.041	0.98
179_T	692_T	1.037	0.97
379_I	578_Q	1.036	0.97
403_D	408_V	1.036	0.97
487_A	526_G	1.030	0.97
229_V	286_A	1.029	0.97
265_M	294_Y	1.028	0.97
275_V	287_L	1.027	0.97
696_K	844_N	1.026	0.97
763_D	773_R	1.025	0.97
861_G	887_P	1.024	0.97
364_H	367_D	1.024	0.97
213_A	297_L	1.023	0.97
412_S	448_K	1.019	0.97
402_M	405_D	1.019	0.97
286_A	289_L	1.019	0.97
199_D	466_R	1.019	0.97
405_D	433_K	1.019	0.97
218_L	292_V	1.017	0.97
212_H	299_P	1.016	0.97
689_G	847_L	1.015	0.97
652_I	814_A	1.014	0.97
230_V	276_V	1.013	0.97
485_H	563_K	1.013	0.97
374_D	502_T	1.012	0.97
175_H	849_L	1.011	0.97
653_I	813_G	1.010	0.97
629_R	818_E	1.007	0.97
414_Q	444_G	1.007	0.97
509_R	546_Y	1.005	0.97
205_M	274_A	1.005	0.97
444_G	686_I	1.002	0.97
756_M	787_K	1.001	0.97
527_P	541_F	0.999	0.97
749_I	781_F	0.994	0.97
495_A	501_L	0.993	0.97
183_K	188_K	0.993	0.97
226_L	285_E	0.993	0.97
643_D	822_N	0.992	0.97
692_T	696_K	0.990	0.97
752_H	784_I	0.990	0.97
376_D	502_T	0.987	0.97
427_V	458_A	0.985	0.97
701_V	742_A	0.984	0.96
218_L	272_V	0.983	0.96
615_S	901_V	0.982	0.96
944_F	948_K	0.982	0.96
744_N	748_K	0.981	0.96
371_G	494_G	0.981	0.96
619_C	836_L	0.978	0.96
227_P	278_E	0.977	0.96
402_M	461_T	0.977	0.96
203_I	460_A	0.976	0.96
679_V	709_V	0.976	0.96
678_I	712_I	0.974	0.96
429_M	462_C	0.973	0.96
766_L	771_V	0.973	0.96
392_P	477_E	0.973	0.96
749_I	784_I	0.971	0.96
475_E	879_R	0.971	0.96
390_Q	447_S	0.965	0.96
401_R	408_V	0.962	0.96
374_D	496_K	0.962	0.96
892_I	896_F	0.961	0.96
231_H	464_T	0.961	0.96
642_G	645_H	0.960	0.96
683_G	730_G	0.957	0.96
212_H	549_N	0.952	0.96
215_I	294_Y	0.951	0.96
233_I	459_W	0.950	0.96
534_Y	569_T	0.950	0.96
360_S	542_Q	0.948	0.96
798_V	801_G	0.947	0.96
307_M	322_V	0.946	0.96
492_K	540_D	0.944	0.96
487_A	510_A	0.941	0.95
304_D	384_N	0.940	0.95
534_Y	587_I	0.939	0.95
819_V	830_L	0.939	0.95
643_D	823_T	0.937	0.95
205_M	271_R	0.933	0.95
235_H	263_K	0.933	0.95
368_M	538_N	0.932	0.95
615_S	618_S	0.932	0.95
573_A	587_I	0.931	0.95
860_I	892_I	0.931	0.95
744_N	799_G	0.928	0.95
615_S	619_C	0.927	0.95
360_S	544_T	0.924	0.95
175_H	846_E	0.923	0.95
183_K	440_R	0.920	0.95
362_H	542_Q	0.919	0.95
708_D	782_G	0.919	0.95
183_K	691_D	0.917	0.95
697_L	843_V	0.917	0.95
644_W	829_R	0.916	0.95
698_A	709_V	0.916	0.95
747_E	751_F	0.916	0.95
747_E	750_L	0.913	0.95
232_V	273_A	0.913	0.95
368_M	505_K	0.912	0.95
505_K	542_Q	0.910	0.95
743_E	747_E	0.910	0.95
434_V	458_A	0.909	0.95
172_I	696_K	0.908	0.95
375_A	503_A	0.908	0.95
220_V	290_I	0.907	0.94
683_G	690_L	0.906	0.94
273_A	290_I	0.904	0.94
591_R	614_P	0.902	0.94
643_D	824_R	0.900	0.94
501_L	575_L	0.899	0.94
270_D	515_Y	0.898	0.94
704_C	708_D	0.897	0.94
740_L	743_E	0.895	0.94
705_P	769_P	0.895	0.94
272_V	292_V	0.895	0.94
849_L	900_L	0.894	0.94
368_M	503_A	0.893	0.94
839_C	848_A	0.890	0.94
303_I	488_K	0.890	0.94
867_E	948_K	0.887	0.94
457_C	470_F	0.885	0.94
202_V	469_L	0.885	0.94
383_Y	574_E	0.884	0.94
833_F	896_F	0.883	0.94
920_V	924_A	0.879	0.94
366_G	371_G	0.878	0.93
574_E	938_W	0.874	0.93
746_R	766_L	0.874	0.93
765_Q	773_R	0.872	0.93
301_M	874_G	0.871	0.93
696_K	845_P	0.870	0.93
217_H	221_S	0.870	0.93
835_A	856_T	0.869	0.93
367_D	538_N	0.869	0.93
372_F	375_A	0.869	0.93
206_L	292_V	0.869	0.93
495_A	571_A	0.868	0.93
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668_M	680_H	0.864	0.93
368_M	540_D	0.864	0.93
630_E	933_D	0.864	0.93
832_K	894_R	0.862	0.93
184_M	191_Y	0.861	0.93
379_I	493_L	0.860	0.93
747_E	761_V	0.858	0.93
494_G	503_A	0.857	0.93
212_H	314_V	0.857	0.93
413_T	419_L	0.855	0.93
644_W	822_N	0.854	0.93
220_V	223_A	0.853	0.92
389_Q	868_I	0.852	0.92
284_L	473_T	0.850	0.92
503_A	538_N	0.849	0.92
491_V	567_A	0.849	0.92
283_A	287_L	0.848	0.92
584_L	617_A	0.846	0.92
302_S	488_K	0.846	0.92
795_G	798_V	0.845	0.92
170_E	700_E	0.844	0.92
871_D	877_L	0.843	0.92
944_F	949_I	0.841	0.92
621_L	626_R	0.841	0.92
571_A	575_L	0.840	0.92
628_G	631_M	0.840	0.92
420_R	431_Q	0.840	0.92
307_M	544_T	0.837	0.92
636_S	641_N	0.834	0.92
396_H	477_E	0.834	0.92
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738_A	742_A	0.832	0.92
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693_V	847_L	0.831	0.91
407_L	462_C	0.827	0.91
798_V	804_I	0.826	0.91
749_I	771_V	0.825	0.91
815_N	922_G	0.824	0.91
859_A	920_V	0.823	0.91
635_S	640_Q	0.823	0.91
192_V	471_R	0.823	0.91
753_G	757_L	0.822	0.91
224_E	236_L	0.821	0.91
688_T	725_A	0.820	0.91
640_Q	644_W	0.819	0.91
376_D	500_R	0.817	0.91
363_G	366_G	0.817	0.91
274_A	456_V	0.817	0.91
266_R	515_Y	0.817	0.91
411_A	419_L	0.816	0.91
668_M	800_T	0.815	0.91
763_D	775_K	0.815	0.91
822_N	827_E	0.814	0.91
380_E	505_K	0.814	0.91
209_P	294_Y	0.814	0.91
207_R	480_A	0.813	0.91
932_H	938_W	0.811	0.90
405_D	462_C	0.811	0.90
667_C	737_A	0.810	0.90
282_I	285_E	0.809	0.90
880_D	883_S	0.808	0.90
228_G	286_A	0.808	0.90
371_G	502_T	0.808	0.90
232_V	275_V	0.808	0.90
403_D	406_R	0.807	0.90
197_T	410_H	0.807	0.90
489_V	506_M	0.806	0.90
779_V	784_I	0.806	0.90
626_R	629_R	0.805	0.90
195_R	410_H	0.804	0.90
757_L	779_V	0.804	0.90
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176_Y	695_T	0.802	0.90
759_E	764_V	0.802	0.90
849_L	853_Y	0.802	0.90
939_L	944_F	0.801	0.90
308_A	311_A	0.800	0.90
300_V	312_P	0.799	0.90
531_L	539_V	0.799	0.90
472_Y	477_E	0.798	0.90
671_L	749_I	0.796	0.90
678_I	710_H	0.796	0.90
300_V	306_A	0.795	0.90
378_I	494_G	0.794	0.90
478_F	881_L	0.794	0.90
770_G	780_S	0.790	0.89
237_N	463_V	0.789	0.89
205_M	456_V	0.788	0.89
819_V	930_A	0.787	0.89
781_F	785_A	0.786	0.89
574_E	578_Q	0.786	0.89
804_I	807_D	0.783	0.89
281_E	285_E	0.782	0.89
215_I	272_V	0.782	0.89
240_D	244_T	0.782	0.89
745_L	799_G	0.781	0.89
839_C	915_I	0.781	0.89
449_Q	726_Y	0.779	0.89
504_V	536_C	0.779	0.89
929_T	938_W	0.779	0.89
202_V	280_E	0.778	0.89
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797_L	805_T	0.777	0.88
499_G	581_I	0.775	0.88
398_C	453_L	0.775	0.88
821_V	949_I	0.772	0.88
606_E	610_P	0.772	0.88
236_L	262_G	0.772	0.88
570_M	928_A	0.772	0.88
494_G	505_K	0.770	0.88
314_V	549_N	0.769	0.88
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798_V	803_Y	0.767	0.88
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586_I	589_R	0.763	0.88
228_G	278_E	0.763	0.88
372_F	502_T	0.762	0.88
417_W	716_T	0.761	0.87
192_V	195_R	0.760	0.87
640_Q	643_D	0.759	0.87
401_R	461_T	0.759	0.87
679_V	738_A	0.758	0.87
304_D	509_R	0.758	0.87
371_G	374_D	0.756	0.87
626_R	650_V	0.756	0.87
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612_S	901_V	0.752	0.87
402_M	407_L	0.752	0.87
213_A	265_M	0.752	0.87
818_E	832_K	0.751	0.87
617_A	652_I	0.751	0.87
301_M	305_E	0.750	0.87
857_L	860_I	0.750	0.87
383_Y	570_M	0.750	0.87
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598_L	604_I	0.747	0.86
568_I	571_A	0.746	0.86
645_H	820_A	0.745	0.86
566_F	570_M	0.744	0.86
388_A	862_H	0.744	0.86
510_A	523_P	0.743	0.86
581_I	585_E	0.743	0.86
261_F	270_D	0.742	0.86
218_L	290_I	0.741	0.86
935_C	952_A	0.741	0.86
171_V	174_K	0.741	0.86
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277_A	286_A	0.740	0.86
224_E	286_A	0.739	0.86
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280_E	473_T	0.737	0.86
571_A	574_E	0.737	0.86
949_I	952_A	0.737	0.86
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526_G	564_G	0.735	0.86
415_V	726_Y	0.734	0.85
632_I	818_E	0.732	0.85
819_V	828_I	0.732	0.85
416_P	716_T	0.731	0.85
501_L	586_I	0.731	0.85
803_Y	807_D	0.731	0.85
386_T	486_V	0.731	0.85
215_I	265_M	0.729	0.85
276_V	468_V	0.728	0.85
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700_E	841_T	0.727	0.85
460_A	464_T	0.726	0.85
313_V	319_V	0.725	0.85
512_T	545_T	0.725	0.85
677_F	745_L	0.724	0.85
208_S	268_V	0.724	0.85
429_M	433_K	0.724	0.85
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566_F	942_W	0.723	0.85
750_L	761_V	0.722	0.85
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175_H	696_K	0.721	0.84
868_I	876_P	0.721	0.84
565_N	925_P	0.721	0.84
412_S	441_V	0.721	0.84
419_L	423_V	0.721	0.84
640_Q	645_H	0.720	0.84
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621_L	816_F	0.716	0.84
601_L	605_G	0.716	0.84
322_V	544_T	0.715	0.84
264_K	314_V	0.715	0.84
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834_Y	899_V	0.714	0.84
172_I	700_E	0.713	0.84
694_V	698_A	0.713	0.84
635_S	641_N	0.713	0.84
371_G	375_A	0.713	0.84
797_L	807_D	0.711	0.84
370_K	538_N	0.711	0.84
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650_V	816_F	0.710	0.84
784_I	788_G	0.709	0.83
731_T	912_A	0.709	0.83
301_M	550_I	0.708	0.83
686_I	725_A	0.708	0.83
464_T	468_V	0.705	0.83
313_V	317_E	0.705	0.83
740_L	801_G	0.704	0.83
680_H	712_I	0.701	0.83
315_H	515_Y	0.701	0.83
211_A	268_V	0.701	0.83
171_V	706_P	0.701	0.83
849_L	898_A	0.701	0.83
427_V	459_W	0.700	0.83
195_R	399_F	0.700	0.83
251_P	255_P	0.700	0.83
642_G	647_G	0.699	0.83
669_I	745_L	0.699	0.83
628_G	632_I	0.698	0.83
519_S	545_T	0.698	0.83
268_V	875_H	0.698	0.83
627_Q	631_M	0.696	0.82
210_H	272_V	0.695	0.82
228_G	282_I	0.694	0.82
179_T	706_P	0.694	0.82
286_A	290_I	0.691	0.82
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837_L	852_I	0.689	0.82
669_I	741_A	0.689	0.82
670_K	680_H	0.688	0.82
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285_E	288_K	0.683	0.81
783_D	787_K	0.683	0.81
309_E	312_P	0.683	0.81
282_I	289_L	0.683	0.81
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400_T	468_V	0.674	0.80
624_I	814_A	0.674	0.80
316_D	319_V	0.674	0.80
596_Q	599_K	0.673	0.80
583_Q	630_E	0.673	0.80
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600_I	604_I	0.671	0.80
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451_I	455_E	0.669	0.80
756_M	784_I	0.669	0.80
385_S	862_H	0.667	0.80
381_R	940_R	0.667	0.80
865_S	885_G	0.667	0.80
203_I	457_C	0.667	0.80
258_R	262_G	0.666	0.79
839_C	900_L	0.665	0.79
702_L	742_A	0.665	0.79
223_A	229_V	0.664	0.79
508_F	526_G	0.664	0.79
260_M	456_V	0.664	0.79
594_E	614_P	0.664	0.79
218_L	232_V	0.663	0.79
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265_M	268_V	0.662	0.79
409_I	458_A	0.661	0.79
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296_V	873_E	0.660	0.79
383_Y	567_A	0.660	0.79
932_H	935_C	0.660	0.79
173_G	696_K	0.659	0.79
703_H	746_R	0.659	0.79
407_L	434_V	0.658	0.79
948_K	951_T	0.657	0.79
852_I	898_A	0.656	0.78
683_G	734_S	0.656	0.78
616_A	901_V	0.656	0.78
690_L	730_G	0.656	0.78
493_L	586_I	0.654	0.78
511_N	548_S	0.652	0.78
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514_P	549_N	0.650	0.78
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617_A	650_V	0.649	0.78
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869_I	877_L	0.647	0.78
296_V	299_P	0.646	0.77
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712_I	718_H	0.645	0.77
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570_M	932_H	0.644	0.77
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674_D	710_H	0.643	0.77
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620_A	834_Y	0.641	0.77
169_L	700_E	0.641	0.77
218_L	234_T	0.640	0.77
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423_V	436_V	0.637	0.76
937_I	952_A	0.637	0.76
268_V	876_P	0.636	0.76
385_S	566_F	0.636	0.76
830_L	833_F	0.635	0.76
570_M	929_T	0.635	0.76
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618_S	621_L	0.632	0.76
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426_L	455_E	0.631	0.76
488_K	509_R	0.630	0.76
767_A	772_V	0.630	0.76
625_L	832_K	0.629	0.76
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204_K	476_E	0.628	0.75
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195_R	439_E	0.627	0.75
530_S	541_F	0.627	0.75
742_A	745_L	0.626	0.75
765_Q	774_G	0.626	0.75
783_D	786_H	0.625	0.75
908_G	912_A	0.624	0.75
229_V	232_V	0.623	0.75
260_M	271_R	0.622	0.75
779_V	787_K	0.622	0.75
801_G	804_I	0.622	0.75
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833_F	923_A	0.620	0.74
703_H	766_L	0.619	0.74
186_Q	189_P	0.619	0.74
758_G	774_G	0.619	0.74
371_G	537_D	0.619	0.74
498_D	502_T	0.618	0.74
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575_L	578_Q	0.613	0.74
828_I	946_P	0.613	0.74
774_G	777_G	0.613	0.74
228_G	277_A	0.612	0.74
231_H	276_V	0.612	0.74
723_K	726_Y	0.611	0.73
298_K	305_E	0.608	0.73
651_A	926_A	0.607	0.73
307_M	488_K	0.607	0.73
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197_T	467_P	0.607	0.73
750_L	754_A	0.606	0.73
565_N	921_N	0.606	0.73
322_V	546_Y	0.606	0.73
657_S	809_A	0.604	0.73
799_G	803_Y	0.603	0.72
395_T	471_R	0.603	0.72
227_P	282_I	0.603	0.72
477_E	481_N	0.602	0.72
796_S	799_G	0.602	0.72
550_I	870_Y	0.602	0.72
815_N	923_A	0.602	0.72
535_P	593_H	0.601	0.72
745_L	797_L	0.601	0.72
531_L	536_C	0.601	0.72
561_A	655_Q	0.601	0.72
647_G	933_D	0.600	0.72
287_L	291_D	0.600	0.72
759_E	772_V	0.600	0.72
234_T	237_N	0.600	0.72
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681_S	694_V	0.599	0.72
835_A	852_I	0.599	0.72
218_L	294_Y	0.598	0.72
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784_I	787_K	0.597	0.72
647_G	657_S	0.595	0.71
766_L	781_F	0.595	0.71
751_F	755_Q	0.595	0.71
396_H	447_S	0.594	0.71
202_V	279_S	0.594	0.71
372_F	376_D	0.593	0.71
928_A	942_W	0.593	0.71
629_R	632_I	0.592	0.71
772_V	776_K	0.592	0.71
199_D	467_P	0.591	0.71
725_A	730_G	0.590	0.71
696_K	700_E	0.590	0.71
420_R	716_T	0.590	0.71
441_V	684_A	0.590	0.71
266_R	547_Y	0.589	0.71
704_C	709_V	0.589	0.71
219_D	223_A	0.589	0.71
362_H	366_G	0.588	0.71
602_G	605_G	0.588	0.71
210_H	292_V	0.585	0.70
727_A	855_A	0.585	0.70
592_V	611_T	0.585	0.70
583_Q	587_I	0.584	0.70
217_H	497_K	0.584	0.70
594_E	612_S	0.584	0.70
797_L	800_T	0.584	0.70
753_G	764_V	0.583	0.70
231_H	460_A	0.582	0.70
223_A	273_A	0.582	0.70
767_A	770_G	0.582	0.70
311_A	314_V	0.582	0.70
313_V	316_D	0.582	0.70
241_I	428_G	0.582	0.70
669_I	677_F	0.582	0.70
224_E	237_N	0.581	0.70
816_F	834_Y	0.581	0.70
821_V	826_G	0.581	0.70
504_V	539_V	0.581	0.70
647_G	821_V	0.581	0.70
377_V	586_I	0.581	0.70
797_L	801_G	0.581	0.70
201_C	468_V	0.580	0.70
172_I	843_V	0.578	0.69
496_K	589_R	0.578	0.69
220_V	236_L	0.578	0.69
752_H	756_M	0.578	0.69
183_K	189_P	0.577	0.69
647_G	656_K	0.575	0.69
207_R	271_R	0.575	0.69
821_V	931_I	0.575	0.69
626_R	648_R	0.575	0.69
799_G	802_S	0.574	0.69
183_K	404_G	0.574	0.69
491_V	575_L	0.574	0.69
620_A	624_I	0.574	0.69
265_M	292_V	0.574	0.69
722_D	734_S	0.574	0.69
582_D	586_I	0.574	0.69
381_R	571_A	0.572	0.68
486_V	553_N	0.572	0.68
794_F	797_L	0.572	0.68
612_S	903_S	0.572	0.68
434_V	873_E	0.572	0.68
522_V	555_A	0.571	0.68
753_G	756_M	0.571	0.68
492_K	503_A	0.571	0.68
367_D	371_G	0.570	0.68
669_I	709_V	0.570	0.68
575_L	581_I	0.570	0.68
495_A	578_Q	0.570	0.68
686_I	690_L	0.569	0.68
211_A	299_P	0.569	0.68
371_G	378_I	0.568	0.68
385_S	489_V	0.568	0.68
510_A	545_T	0.568	0.68
423_V	428_G	0.568	0.68
258_R	263_K	0.567	0.68
752_H	755_Q	0.567	0.68
260_M	272_V	0.566	0.68
702_L	749_I	0.566	0.68
685_D	691_D	0.565	0.68
629_R	633_Q	0.565	0.68
212_H	265_M	0.565	0.68
811_P	837_L	0.564	0.67
379_I	575_L	0.562	0.67
215_I	235_H	0.562	0.67
522_V	560_G	0.561	0.67
757_L	764_V	0.561	0.67
376_D	495_A	0.560	0.67
379_I	586_I	0.559	0.67
261_F	265_M	0.559	0.67
366_G	538_N	0.559	0.67
266_R	314_V	0.558	0.67
787_K	791_G	0.558	0.67
452_L	456_V	0.557	0.66
624_I	627_Q	0.557	0.66
730_G	734_S	0.557	0.66
754_A	764_V	0.557	0.66
203_I	276_V	0.557	0.66
826_G	950_L	0.556	0.66
304_D	307_M	0.556	0.66
516_G	547_Y	0.556	0.66
578_Q	938_W	0.556	0.66
420_R	424_A	0.555	0.66
402_M	434_V	0.555	0.66
512_T	553_N	0.555	0.66
632_I	636_S	0.555	0.66
371_G	376_D	0.554	0.66
648_R	820_A	0.553	0.66
641_N	820_A	0.553	0.66
623_E	834_Y	0.552	0.66
629_R	648_R	0.552	0.66
190_C	195_R	0.551	0.66
694_V	734_S	0.551	0.66
502_T	537_D	0.549	0.65
591_R	611_T	0.549	0.65
758_G	775_K	0.549	0.65
416_P	684_A	0.549	0.65
235_H	239_P	0.548	0.65
268_V	479_I	0.548	0.65
202_V	471_R	0.548	0.65
370_K	497_K	0.547	0.65
201_C	231_H	0.547	0.65
473_T	476_E	0.547	0.65
227_P	230_V	0.547	0.65
667_C	681_S	0.546	0.65
617_A	621_L	0.545	0.65
739_R	910_F	0.545	0.65
641_N	644_W	0.545	0.65
374_D	497_K	0.544	0.65
536_C	568_I	0.543	0.65
613_V	616_A	0.543	0.65
619_C	901_V	0.543	0.65
391_C	868_I	0.543	0.65
935_C	953_L	0.543	0.65
579_L	589_R	0.542	0.64
513_G	552_P	0.542	0.64
399_F	469_L	0.542	0.64
389_Q	392_P	0.541	0.64
822_N	825_T	0.540	0.64
879_R	883_S	0.540	0.64
255_P	547_Y	0.540	0.64
373_A	751_F	0.540	0.64
741_A	801_G	0.540	0.64
173_G	845_P	0.540	0.64
226_L	277_A	0.539	0.64
506_M	567_A	0.539	0.64
779_V	783_D	0.538	0.64
300_V	305_E	0.537	0.64
704_C	781_F	0.537	0.64
257_D	270_D	0.537	0.64
518_H	559_Y	0.536	0.64
885_G	888_K	0.535	0.63
858_R	861_G	0.535	0.63
665_A	682_G	0.534	0.63
299_P	549_N	0.534	0.63
666_N	720_L	0.534	0.63
576_A	581_I	0.534	0.63
682_G	719_A	0.534	0.63
858_R	887_P	0.533	0.63
416_P	722_D	0.533	0.63
559_Y	727_A	0.533	0.63
748_K	751_F	0.533	0.63
279_S	285_E	0.532	0.63
388_A	556_Y	0.532	0.63
671_L	677_F	0.531	0.63
412_S	444_G	0.531	0.63
219_D	222_K	0.531	0.63
275_V	292_V	0.530	0.63
592_V	598_L	0.530	0.63
658_G	727_A	0.530	0.63
518_H	521_T	0.530	0.63
583_Q	929_T	0.530	0.63
390_Q	483_S	0.529	0.63
398_C	411_A	0.528	0.62
214_L	217_H	0.528	0.62
573_A	938_W	0.526	0.62
472_Y	481_N	0.526	0.62
750_L	765_Q	0.526	0.62
450_D	517_N	0.525	0.62
842_P	849_L	0.525	0.62
300_V	546_Y	0.524	0.62
257_D	261_F	0.524	0.62
948_K	952_A	0.523	0.62
588_E	617_A	0.523	0.62
621_L	650_V	0.523	0.62
635_S	933_D	0.523	0.62
437_I	715_D	0.522	0.61
672_E	710_H	0.522	0.61
225_A	282_I	0.522	0.61
411_A	454_E	0.521	0.61
655_Q	921_N	0.521	0.61
939_L	949_I	0.520	0.61
181_A	690_L	0.519	0.61
796_S	802_S	0.519	0.61
690_L	725_A	0.519	0.61
499_G	589_R	0.518	0.61
258_R	261_F	0.517	0.61
389_Q	483_S	0.516	0.61
656_K	810_F	0.515	0.60
388_A	484_R	0.514	0.60
293_E	296_V	0.514	0.60
510_A	526_G	0.514	0.60
809_A	905_D	0.514	0.60
219_D	293_E	0.513	0.60
232_V	286_A	0.513	0.60
260_M	274_A	0.513	0.60
712_I	719_A	0.513	0.60
399_F	410_H	0.512	0.60
597_E	603_A	0.512	0.60
629_R	832_K	0.511	0.60
853_Y	896_F	0.510	0.60
459_W	463_V	0.510	0.60
746_R	771_V	0.509	0.60
389_Q	478_F	0.509	0.60
525_N	529_L	0.509	0.60
476_E	480_A	0.509	0.60
781_F	790_T	0.508	0.59
204_K	290_I	0.508	0.59
559_Y	726_Y	0.507	0.59
478_F	876_P	0.507	0.59
694_V	711_V	0.507	0.59
838_D	904_D	0.506	0.59
604_I	610_P	0.506	0.59
562_P	920_V	0.506	0.59
405_D	465_G	0.506	0.59
256_L	516_G	0.505	0.59
925_P	928_A	0.505	0.59
754_A	760_P	0.505	0.59
259_R	426_L	0.505	0.59
176_Y	692_T	0.504	0.59
493_L	568_I	0.504	0.59
848_A	852_I	0.504	0.59
493_L	572_L	0.504	0.59
556_Y	920_V	0.504	0.59
940_R	952_A	0.504	0.59
218_L	226_L	0.503	0.59
424_A	431_Q	0.503	0.59
211_A	871_D	0.503	0.59
815_N	835_A	0.503	0.59
641_N	823_T	0.503	0.59
230_V	464_T	0.502	0.59
305_E	309_E	0.502	0.59
670_K	678_I	0.502	0.59
627_Q	630_E	0.502	0.59
490_T	509_R	0.501	0.58
622_E	625_L	0.501	0.58
449_Q	518_H	0.500	0.58
644_W	831_D	0.500	0.58
305_E	310_D	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3uncA	2	0.9236	100	0.171	Contact Map
3zyvA	3	0.9163	100	0.176	Contact Map
1dgjA	1	0.9215	100	0.192	Contact Map
4usaA	2	0.9236	100	0.193	Contact Map
1rm6A	2	0.7626	100	0.351	Contact Map
1t3qB	2	0.7908	100	0.352	Contact Map
1ffvB	2	0.7981	100	0.357	Contact Map
1n62B	2	0.8065	100	0.358	Contact Map
2w3sB	2	0.7605	100	0.362	Contact Map
3nvzC	2	0.7531	100	0.374	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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