ARCL - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

ARCL - Carbamate kinase-like protein YqeA

UniProt:	Q46807	Sequences: MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIVTHGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGINKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVVASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLAEMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAAASFARSRAGREALITVLSKAKEGIEGKTGTVICQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13057
Length:	310 (296)
Sequences:	1302 (833)
Seq/√Len:	48.4

ECOLI - ARCL ARCM ARCC
HALSA - ARCC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
135_E	139_E	6.405	1.00
256_E	281_R	6.386	1.00
250_L	255_A	4.233	1.00
236_A	246_W	3.684	1.00
4_K	41_E	3.681	1.00
238_N	243_N	3.636	1.00
134_T	137_E	3.342	1.00
247_L	250_L	3.301	1.00
234_K	248_D	3.297	1.00
32_I	42_V	3.022	1.00
45_T	214_S	2.959	1.00
75_S	205_S	2.935	1.00
197_E	202_R	2.611	1.00
257_R	261_E	2.577	1.00
238_N	263_H	2.491	1.00
234_K	246_W	2.396	1.00
287_E	307_V	2.342	1.00
55_I	81_S	2.334	1.00
249_R	309_C	2.320	1.00
30_Q	96_E	2.282	1.00
291_T	299_G	2.248	1.00
135_E	156_Y	2.231	1.00
187_V	213_A	2.203	1.00
90_Q	108_T	2.163	1.00
6_V	223_A	2.108	1.00
7_L	32_I	2.076	1.00
295_K	298_E	2.066	1.00
164_K	278_S	2.051	1.00
216_R	220_M	2.036	1.00
146_Y	158_R	2.033	1.00
187_V	217_L	1.987	0.99
280_A	288_A	1.967	0.99
227_I	296_A	1.946	0.99
229_L	296_A	1.916	0.99
237_I	245_Q	1.874	0.99
114_E	196_R	1.830	0.99
124_N	149_K	1.821	0.99
280_A	284_A	1.816	0.99
114_E	167_D	1.804	0.99
33_V	93_L	1.803	0.99
140_Q	143_K	1.790	0.99
214_S	226_L	1.781	0.99
233_E	236_A	1.752	0.99
117_A	197_E	1.746	0.99
252_L	277_A	1.741	0.99
237_I	263_H	1.715	0.98
298_E	303_K	1.711	0.98
167_D	220_M	1.704	0.98
132_F	154_R	1.689	0.98
57_Q	133_F	1.683	0.98
258_F	261_E	1.645	0.98
222_D	286_R	1.644	0.98
291_T	304_T	1.643	0.98
255_A	308_I	1.611	0.98
233_E	304_T	1.596	0.97
215_A	219_E	1.556	0.97
41_E	181_G	1.532	0.97
225_M	289_L	1.508	0.96
251_S	254_D	1.507	0.96
43_I	221_I	1.484	0.96
34_D	297_K	1.477	0.96
212_W	274_E	1.476	0.96
238_N	245_Q	1.467	0.96
5_I	40_H	1.454	0.95
197_E	200_H	1.446	0.95
266_K	270_L	1.437	0.95
219_E	278_S	1.429	0.95
34_D	37_A	1.399	0.94
142_T	148_L	1.392	0.94
167_D	196_R	1.389	0.94
128_P	149_K	1.380	0.94
74_M	78_V	1.378	0.94
139_E	156_Y	1.376	0.94
58_A	84_Y	1.375	0.94
176_A	180_A	1.358	0.93
171_K	221_I	1.343	0.93
175_K	179_D	1.342	0.93
167_D	171_K	1.342	0.93
105_P	172_E	1.328	0.93
240_G	244_E	1.321	0.93
234_K	304_T	1.315	0.92
107_A	173_T	1.311	0.92
114_E	169_I	1.310	0.92
76_V	88_D	1.307	0.92
16_D	20_G	1.288	0.92
245_Q	254_D	1.283	0.91
289_L	299_G	1.280	0.91
58_A	80_L	1.251	0.90
96_E	99_S	1.247	0.90
57_Q	131_S	1.246	0.90
94_R	106_V	1.241	0.90
276_A	288_A	1.241	0.90
265_A	270_L	1.241	0.90
254_D	257_R	1.231	0.90
238_N	241_K	1.227	0.89
173_T	182_Q	1.225	0.89
236_A	239_F	1.221	0.89
15_G	20_G	1.221	0.89
215_A	278_S	1.213	0.89
97_L	106_V	1.210	0.89
43_I	178_V	1.209	0.89
36_I	183_V	1.205	0.89
14_L	54_M	1.191	0.88
236_A	244_E	1.186	0.88
227_I	289_L	1.184	0.88
132_F	150_E	1.184	0.88
273_V	288_A	1.182	0.88
55_I	58_A	1.174	0.87
128_P	132_F	1.174	0.87
187_V	214_S	1.173	0.87
59_F	80_L	1.160	0.87
233_E	295_K	1.155	0.86
150_E	154_R	1.146	0.86
225_M	287_E	1.136	0.85
138_A	145_G	1.135	0.85
91_N	112_Q	1.133	0.85
151_D	154_R	1.131	0.85
90_Q	112_Q	1.130	0.85
87_Y	203_G	1.118	0.84
97_L	183_V	1.112	0.84
112_Q	201_L	1.106	0.84
291_T	295_K	1.105	0.84
174_V	186_T	1.101	0.84
256_E	277_A	1.093	0.83
22_M	92_A	1.090	0.83
81_S	84_Y	1.084	0.83
15_G	56_N	1.080	0.82
133_F	141_L	1.075	0.82
87_Y	91_N	1.067	0.82
103_N	172_E	1.057	0.81
216_R	219_E	1.056	0.81
138_A	142_T	1.056	0.81
142_T	156_Y	1.040	0.80
178_V	221_I	1.037	0.80
141_L	148_L	1.035	0.80
116_D	166_V	1.034	0.79
18_L	76_V	1.034	0.79
256_E	274_E	1.031	0.79
78_V	113_V	1.030	0.79
18_L	75_S	1.029	0.79
80_L	84_Y	1.027	0.79
142_T	146_Y	1.025	0.79
90_Q	185_I	1.020	0.79
249_R	307_V	1.015	0.78
168_I	217_L	1.011	0.78
25_V	89_L	1.005	0.78
42_V	183_V	1.002	0.77
38_Q	301_E	1.002	0.77
133_F	148_L	0.997	0.77
5_I	35_L	0.995	0.77
76_V	84_Y	0.992	0.77
173_T	176_A	0.977	0.75
54_M	58_A	0.974	0.75
280_A	309_C	0.970	0.75
5_I	293_L	0.967	0.75
87_Y	112_Q	0.964	0.75
235_V	290_I	0.964	0.75
49_G	267_G	0.962	0.74
4_K	40_H	0.960	0.74
250_L	258_F	0.959	0.74
297_K	301_E	0.956	0.74
59_F	69_S	0.948	0.73
18_L	72_L	0.941	0.73
18_L	58_A	0.939	0.73
164_K	274_E	0.939	0.73
237_I	247_L	0.933	0.72
90_Q	110_V	0.929	0.72
55_I	77_C	0.928	0.72
128_P	265_A	0.923	0.71
54_M	59_F	0.923	0.71
54_M	84_Y	0.921	0.71
18_L	88_D	0.921	0.71
252_L	256_E	0.918	0.71
132_F	151_D	0.913	0.70
41_E	104_K	0.912	0.70
23_K	26_K	0.909	0.70
258_F	264_F	0.903	0.70
139_E	142_T	0.902	0.69
62_A	72_L	0.902	0.69
113_V	214_S	0.901	0.69
4_K	178_V	0.899	0.69
69_S	88_D	0.896	0.69
112_Q	169_I	0.895	0.69
9_L	13_A	0.888	0.68
166_V	216_R	0.886	0.68
59_F	84_Y	0.886	0.68
17_D	20_G	0.881	0.68
149_K	156_Y	0.874	0.67
169_I	201_L	0.866	0.66
248_D	307_V	0.864	0.66
13_A	229_L	0.862	0.66
117_A	195_I	0.862	0.66
62_A	68_H	0.861	0.66
289_L	307_V	0.856	0.65
61_A	131_S	0.855	0.65
121_A	126_T	0.853	0.65
9_L	293_L	0.847	0.65
293_L	296_A	0.846	0.64
14_L	85_I	0.838	0.64
44_V	89_L	0.837	0.64
113_V	213_A	0.837	0.64
174_V	187_V	0.834	0.63
36_I	39_G	0.830	0.63
240_G	280_A	0.823	0.62
25_V	92_A	0.822	0.62
164_K	212_W	0.822	0.62
29_S	92_A	0.819	0.62
75_S	87_Y	0.812	0.61
22_M	88_D	0.812	0.61
29_S	89_L	0.806	0.61
237_I	258_F	0.802	0.60
95_E	198_G	0.801	0.60
95_E	187_V	0.800	0.60
166_V	171_K	0.798	0.60
135_E	150_E	0.796	0.60
59_F	81_S	0.793	0.59
26_K	92_A	0.789	0.59
15_G	54_M	0.787	0.59
94_R	201_L	0.786	0.59
229_L	293_L	0.786	0.59
78_V	84_Y	0.784	0.59
99_S	199_N	0.773	0.57
105_P	182_Q	0.772	0.57
142_T	149_K	0.770	0.57
81_S	110_V	0.766	0.57
111_T	168_I	0.766	0.57
177_L	184_V	0.765	0.57
237_I	242_E	0.760	0.56
142_T	145_G	0.757	0.56
212_W	275_A	0.755	0.56
298_E	304_T	0.750	0.55
31_A	34_D	0.744	0.55
129_I	160_V	0.743	0.55
264_F	273_V	0.743	0.55
120_P	123_L	0.743	0.55
19_A	23_K	0.741	0.54
236_A	248_D	0.734	0.54
62_A	69_S	0.730	0.53
176_A	182_Q	0.730	0.53
75_S	88_D	0.725	0.53
58_A	88_D	0.723	0.52
40_H	224_D	0.722	0.52
55_I	84_Y	0.719	0.52
255_A	273_V	0.717	0.52
14_L	59_F	0.714	0.52
45_T	187_V	0.714	0.52
35_L	296_A	0.713	0.51
196_R	201_L	0.710	0.51
75_S	131_S	0.709	0.51
298_E	301_E	0.703	0.50
18_L	84_Y	0.701	0.50
107_A	182_Q	0.701	0.50
44_V	183_V	0.698	0.50
292_V	295_K	0.698	0.50
185_I	228_I	0.697	0.50
75_S	84_Y	0.697	0.50
24_A	74_M	0.696	0.50
56_N	75_S	0.695	0.50
22_M	91_N	0.693	0.49
224_D	286_R	0.692	0.49
195_I	204_A	0.691	0.49
20_G	24_A	0.690	0.49
79_A	285_G	0.689	0.49
245_Q	248_D	0.689	0.49
12_N	49_G	0.687	0.49
167_D	216_R	0.684	0.49
12_N	162_S	0.670	0.47
24_A	88_D	0.669	0.47
89_L	93_L	0.668	0.47
174_V	217_L	0.666	0.47
72_L	76_V	0.666	0.47
47_G	209_D	0.666	0.47
232_V	239_F	0.665	0.47
175_K	222_D	0.661	0.46
95_E	112_Q	0.657	0.46
27_I	294_S	0.654	0.46
129_I	156_Y	0.653	0.45
74_M	88_D	0.652	0.45
11_G	47_G	0.652	0.45
148_L	158_R	0.652	0.45
281_R	285_G	0.650	0.45
169_I	194_V	0.649	0.45
36_I	102_I	0.649	0.45
150_E	153_G	0.647	0.45
225_M	296_A	0.646	0.45
114_E	117_A	0.645	0.45
34_D	39_G	0.643	0.44
74_M	205_S	0.642	0.44
239_F	262_G	0.642	0.44
120_P	242_E	0.641	0.44
11_G	209_D	0.641	0.44
9_L	21_Q	0.638	0.44
132_F	155_G	0.638	0.44
121_A	275_A	0.637	0.44
45_T	113_V	0.636	0.44
37_A	239_F	0.631	0.43
295_K	304_T	0.631	0.43
235_V	263_H	0.629	0.43
63_A	131_S	0.629	0.43
94_R	112_Q	0.629	0.43
114_E	201_L	0.625	0.43
94_R	105_P	0.623	0.42
171_K	220_M	0.623	0.42
212_W	278_S	0.622	0.42
186_T	299_G	0.622	0.42
233_E	292_V	0.621	0.42
95_E	199_N	0.621	0.42
253_S	281_R	0.621	0.42
13_A	293_L	0.621	0.42
56_N	74_M	0.620	0.42
142_T	158_R	0.619	0.42
14_L	88_D	0.616	0.42
251_S	255_A	0.615	0.42
21_Q	85_I	0.615	0.42
18_L	73_P	0.614	0.42
26_K	95_E	0.614	0.42
37_A	167_D	0.613	0.41
138_A	156_Y	0.613	0.41
62_A	161_A	0.613	0.41
146_Y	270_L	0.611	0.41
81_S	185_I	0.610	0.41
107_A	177_L	0.608	0.41
110_V	197_E	0.606	0.41
281_R	308_I	0.606	0.41
32_I	234_K	0.606	0.41
122_F	204_A	0.605	0.41
25_V	54_M	0.604	0.41
84_Y	231_A	0.603	0.41
209_D	267_G	0.602	0.40
124_N	266_K	0.602	0.40
94_R	170_E	0.601	0.40
72_L	84_Y	0.600	0.40
24_A	291_T	0.597	0.40
273_V	308_I	0.596	0.40
154_R	231_A	0.596	0.40
129_I	161_A	0.593	0.40
282_S	286_R	0.590	0.39
144_Q	148_L	0.589	0.39
7_L	35_L	0.587	0.39
174_V	208_I	0.585	0.39
11_G	162_S	0.581	0.38
113_V	186_T	0.581	0.38
144_Q	158_R	0.580	0.38
99_S	245_Q	0.579	0.38
228_I	244_E	0.577	0.38
84_Y	88_D	0.577	0.38
212_W	219_E	0.577	0.38
252_L	255_A	0.577	0.38
234_K	250_L	0.576	0.38
15_G	76_V	0.573	0.38
222_D	249_R	0.573	0.38
219_E	282_S	0.572	0.38
93_L	183_V	0.572	0.38
54_M	80_L	0.571	0.37
108_T	185_I	0.570	0.37
229_L	300_I	0.570	0.37
128_P	150_E	0.570	0.37
95_E	200_H	0.569	0.37
24_A	231_A	0.568	0.37
161_A	171_K	0.567	0.37
277_A	281_R	0.565	0.37
28_T	291_T	0.563	0.37
58_A	75_S	0.563	0.37
45_T	186_T	0.562	0.37
54_M	81_S	0.562	0.37
59_F	88_D	0.561	0.36
56_N	59_F	0.560	0.36
17_D	129_I	0.559	0.36
59_F	75_S	0.558	0.36
256_E	261_E	0.558	0.36
295_K	299_G	0.557	0.36
35_L	300_I	0.555	0.36
14_L	84_Y	0.555	0.36
178_V	181_G	0.554	0.36
141_L	146_Y	0.554	0.36
36_I	97_L	0.553	0.36
36_I	104_K	0.551	0.36
78_V	231_A	0.550	0.35
231_A	296_A	0.549	0.35
120_P	253_S	0.548	0.35
32_I	44_V	0.545	0.35
42_V	286_R	0.543	0.35
35_L	102_I	0.543	0.35
15_G	59_F	0.543	0.35
54_M	88_D	0.538	0.34
14_L	56_N	0.537	0.34
23_K	27_I	0.536	0.34
106_V	129_I	0.535	0.34
90_Q	170_E	0.534	0.34
243_N	261_E	0.534	0.34
238_N	261_E	0.533	0.34
237_I	264_F	0.533	0.34
18_L	78_V	0.531	0.34
49_G	162_S	0.531	0.34
239_F	265_A	0.531	0.34
231_A	265_A	0.530	0.34
90_Q	97_L	0.529	0.34
72_L	133_F	0.527	0.33
63_A	68_H	0.527	0.33
56_N	158_R	0.527	0.33
56_N	60_E	0.525	0.33
94_R	98_L	0.525	0.33
77_C	84_Y	0.524	0.33
105_P	173_T	0.522	0.33
25_V	78_V	0.522	0.33
161_A	205_S	0.521	0.33
78_V	82_Q	0.521	0.33
25_V	226_L	0.521	0.33
72_L	77_C	0.521	0.33
12_N	267_G	0.520	0.33
5_I	300_I	0.520	0.33
248_D	255_A	0.520	0.33
87_Y	192_I	0.518	0.33
25_V	88_D	0.517	0.32
40_H	70_P	0.517	0.32
58_A	131_S	0.516	0.32
276_A	308_I	0.516	0.32
29_S	93_L	0.514	0.32
83_G	110_V	0.514	0.32
24_A	58_A	0.514	0.32
20_G	75_S	0.513	0.32
74_M	146_Y	0.512	0.32
9_L	79_A	0.512	0.32
14_L	215_A	0.512	0.32
82_Q	302_G	0.511	0.32
155_G	232_V	0.511	0.32
137_E	140_Q	0.511	0.32
299_G	304_T	0.509	0.32
72_L	81_S	0.509	0.32
131_S	158_R	0.508	0.32
44_V	185_I	0.507	0.32
289_L	300_I	0.506	0.32
57_Q	121_A	0.505	0.31
22_M	74_M	0.504	0.31
56_N	81_S	0.504	0.31
16_D	24_A	0.503	0.31
57_Q	61_A	0.503	0.31
20_G	56_N	0.501	0.31
7_L	42_V	0.501	0.31
60_E	299_G	0.501	0.31
156_Y	273_V	0.501	0.31
15_G	24_A	0.501	0.31
80_L	88_D	0.500	0.31
109_L	174_V	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1e19A	2	0.9903	100	0.486	Contact Map
2e9yA	2	0.9806	100	0.493	Contact Map
4axsA	2	0.9355	100	0.501	Contact Map
2we5A	2	0.9839	100	0.505	Contact Map
4jz8A	2	0.9871	100	0.51	Contact Map
3l86A	1	0.7742	100	0.711	Contact Map
2bufA	3	0.8097	100	0.715	Contact Map
3wwnA	2	0.8097	100	0.715	Contact Map
2rd5A	3	0.8355	100	0.719	Contact Map
2ap9A	3	0.829	100	0.724	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0102 seconds.