PHYDA - ECOLI - GREMLIN Contacts

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PHYDA - D-phenylhydantoinase

UniProt:	Q46806	Sequences: MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEIDATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMIVEEGLSSFKLYLTYQYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVVIIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13056
Length:	461 (418)
Sequences:	9700 (6435)
Seq/√Len:	314.8

ECOLI - PHYDA ALLB PYRC
BACSU - PYRC ALLB
HALSA - PYRC
SULSO - PYRC Q97VT3 Q97WS6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
5_I	46_A	4.633	1.00
429_L	434_T	3.882	1.00
49_C	426_V	3.871	1.00
228_Q	255_N	3.647	1.00
8_G	51_V	3.396	1.00
399_S	420_T	3.387	1.00
427_R	434_T	3.286	1.00
361_R	364_E	3.265	1.00
24_E	29_R	3.262	1.00
10_V	19_Q	3.233	1.00
42_E	437_C	3.149	1.00
8_G	46_A	3.082	1.00
21_L	51_V	3.008	1.00
32_G	35_I	2.982	1.00
383_L	391_V	2.900	1.00
30_Q	385_P	2.816	1.00
6_K	43_E	2.768	1.00
358_T	361_R	2.734	1.00
292_V	296_D	2.715	1.00
380_K	388_D	2.599	1.00
382_L	387_S	2.536	1.00
3_V	429_L	2.525	1.00
404_H	417_E	2.489	1.00
369_M	372_R	2.474	1.00
49_C	393_I	2.466	1.00
46_A	393_I	2.388	1.00
83_A	120_I	2.375	1.00
403_Q	406_H	2.352	1.00
23_I	391_V	2.345	1.00
220_I	245_G	2.294	1.00
4_L	22_L	2.282	1.00
51_V	393_I	2.246	1.00
52_F	394_I	2.233	1.00
121_D	431_R	2.182	1.00
9_T	18_K	2.137	1.00
54_G	88_T	2.134	1.00
263_T	267_Y	2.108	1.00
292_V	295_Q	2.079	1.00
84_C	436_F	2.053	1.00
402_I	421_C	2.043	1.00
253_R	308_D	2.028	1.00
258_P	373_L	1.986	1.00
384_A	387_S	1.929	1.00
236_Y	260_W	1.927	1.00
58_V	374_F	1.921	1.00
27_I	379_Q	1.905	1.00
49_C	395_D	1.902	1.00
353_M	422_Q	1.893	1.00
364_E	369_M	1.891	1.00
31_L	385_P	1.873	1.00
108_E	112_G	1.836	1.00
171_R	174_E	1.827	1.00
83_A	435_I	1.817	1.00
372_R	382_L	1.814	1.00
26_G	388_D	1.809	1.00
84_C	408_H	1.799	1.00
329_D	332_R	1.788	1.00
399_S	422_Q	1.775	1.00
400_Q	424_A	1.772	1.00
10_V	21_L	1.762	1.00
138_E	141_M	1.755	1.00
50_Y	359_P	1.750	1.00
243_G	293_R	1.736	1.00
7_N	45_D	1.726	1.00
395_D	398_Q	1.719	1.00
427_R	437_C	1.718	1.00
350_S	354_T	1.717	1.00
224_I	259_V	1.699	1.00
364_E	368_A	1.694	1.00
89_T	123_S	1.682	1.00
109_V	113_Y	1.681	1.00
44_I	429_L	1.668	1.00
217_A	244_L	1.665	1.00
398_Q	426_V	1.655	1.00
19_Q	31_L	1.650	1.00
221_A	248_Y	1.641	1.00
6_K	20_D	1.637	1.00
22_L	41_Y	1.631	1.00
16_Q	360_E	1.624	1.00
20_D	35_I	1.622	1.00
398_Q	424_A	1.613	1.00
52_F	363_V	1.613	1.00
251_L	255_N	1.613	1.00
172_L	179_T	1.610	1.00
3_V	23_I	1.609	1.00
401_Q	420_T	1.608	1.00
227_A	235_L	1.604	1.00
76_F	80_R	1.596	1.00
347_L	366_T	1.591	1.00
62_F	78_G	1.573	1.00
224_I	248_Y	1.562	1.00
347_L	362_F	1.562	1.00
166_L	229_I	1.559	1.00
87_T	343_R	1.549	1.00
8_G	393_I	1.542	1.00
143_V	177_A	1.542	1.00
434_T	437_C	1.540	1.00
264_C	267_Y	1.536	1.00
55_G	344_M	1.491	1.00
271_D	292_V	1.471	1.00
250_R	304_D	1.465	1.00
309_V	373_L	1.459	1.00
240_L	249_L	1.456	1.00
352_V	362_F	1.449	1.00
395_D	426_V	1.444	1.00
221_A	225_N	1.442	1.00
247_D	251_L	1.441	1.00
378_P	387_S	1.438	1.00
161_N	164_E	1.438	1.00
22_L	30_Q	1.432	1.00
27_I	388_D	1.429	1.00
51_V	391_V	1.423	1.00
21_L	383_L	1.418	1.00
363_V	367_S	1.417	1.00
361_R	365_L	1.406	1.00
5_I	393_I	1.396	1.00
71_S	318_S	1.378	1.00
428_T	436_F	1.375	1.00
140_P	171_R	1.373	1.00
5_I	23_I	1.359	1.00
74_D	410_N	1.357	1.00
270_L	346_L	1.356	1.00
426_V	438_D	1.345	1.00
403_Q	417_E	1.345	1.00
4_L	40_P	1.338	1.00
58_V	309_V	1.330	1.00
368_A	372_R	1.316	1.00
379_Q	388_D	1.308	1.00
251_L	254_A	1.301	1.00
44_I	427_R	1.300	1.00
249_L	261_V	1.300	1.00
285_L	337_L	1.298	1.00
22_L	40_P	1.292	1.00
225_N	229_I	1.285	1.00
228_Q	257_Q	1.279	1.00
271_D	274_S	1.274	1.00
73_D	78_G	1.269	1.00
50_Y	396_P	1.262	1.00
268_L	298_L	1.257	1.00
42_E	434_T	1.254	1.00
388_D	431_R	1.230	1.00
357_I	365_L	1.219	1.00
52_F	392_V	1.218	1.00
180_T	238_V	1.200	1.00
172_L	177_A	1.199	1.00
80_R	408_H	1.194	1.00
230_A	233_A	1.194	1.00
95_G	98_P	1.190	1.00
112_G	116_H	1.185	1.00
213_L	244_L	1.182	1.00
32_G	36_S	1.182	1.00
100_G	103_L	1.173	1.00
52_F	55_G	1.171	1.00
250_R	306_A	1.165	1.00
261_V	307_I	1.161	1.00
291_N	294_E	1.161	1.00
169_L	233_A	1.157	1.00
227_A	257_Q	1.156	1.00
40_P	43_E	1.154	1.00
243_G	297_K	1.149	1.00
3_V	42_E	1.145	1.00
109_V	112_G	1.139	1.00
269_L	346_L	1.135	1.00
56_V	371_A	1.133	1.00
402_I	407_L	1.133	1.00
55_G	366_T	1.132	1.00
171_R	175_S	1.128	1.00
17_A	33_N	1.127	1.00
199_A	203_A	1.125	1.00
62_F	90_I	1.123	1.00
205_R	276_D	1.121	1.00
224_I	252_A	1.117	1.00
393_I	427_R	1.114	1.00
430_S	435_I	1.109	1.00
185_N	218_E	1.098	1.00
240_L	245_G	1.079	1.00
300_C	304_D	1.068	1.00
195_E	199_A	1.068	1.00
220_I	237_I	1.066	1.00
18_K	47_T	1.065	1.00
302_I	365_L	1.065	1.00
5_I	51_V	1.064	1.00
296_D	300_C	1.062	1.00
46_A	51_V	1.062	1.00
132_N	135_I	1.046	1.00
10_V	17_A	1.044	1.00
79_T	118_A	1.041	1.00
10_V	383_L	1.037	1.00
11_V	50_Y	1.033	1.00
338_P	411_A	1.033	1.00
102_R	105_H	1.030	1.00
349_S	422_Q	1.028	1.00
328_G	332_R	1.017	1.00
349_S	353_M	1.016	1.00
74_D	77_T	1.015	1.00
176_G	375_G	1.013	1.00
20_D	32_G	1.010	1.00
169_L	179_T	1.009	1.00
284_I	333_C	1.006	1.00
242_N	245_G	1.005	1.00
30_Q	35_I	0.998	1.00
58_V	370_P	0.997	1.00
19_Q	33_N	0.995	1.00
22_L	35_I	0.991	1.00
150_F	177_A	0.989	1.00
11_V	363_V	0.986	1.00
5_I	429_L	0.981	1.00
91_I	125_H	0.980	1.00
161_N	187_A	0.979	1.00
5_I	391_V	0.971	1.00
8_G	391_V	0.971	1.00
9_T	50_Y	0.966	1.00
170_R	174_E	0.964	1.00
371_A	381_G	0.955	1.00
349_S	419_F	0.954	1.00
62_F	79_T	0.954	1.00
223_M	235_L	0.953	1.00
224_I	257_Q	0.948	1.00
393_I	429_L	0.945	1.00
125_H	149_S	0.943	1.00
167_Q	170_R	0.943	1.00
91_I	123_S	0.942	1.00
359_P	396_P	0.939	1.00
94_M	98_P	0.937	1.00
14_D	382_L	0.936	1.00
19_Q	383_L	0.934	1.00
310_V	347_L	0.934	1.00
362_F	366_T	0.933	1.00
178_L	234_P	0.932	1.00
345_Q	400_Q	0.930	1.00
381_G	390_D	0.927	1.00
248_Y	251_L	0.926	1.00
121_D	380_K	0.923	1.00
11_V	16_Q	0.920	1.00
83_A	428_T	0.920	1.00
297_K	301_G	0.918	1.00
318_S	321_Q	0.918	1.00
195_E	198_A	0.917	1.00
140_P	144_E	0.913	1.00
4_L	20_D	0.909	1.00
74_D	117_K	0.908	1.00
130_H	135_I	0.908	1.00
391_V	429_L	0.905	1.00
234_P	258_P	0.904	1.00
136_L	145_E	0.896	1.00
164_E	167_Q	0.890	1.00
344_M	348_F	0.882	1.00
23_I	429_L	0.882	1.00
165_V	181_V	0.881	1.00
342_N	402_I	0.881	1.00
55_G	87_T	0.873	1.00
15_G	360_E	0.872	1.00
94_M	97_G	0.870	1.00
140_P	174_E	0.866	1.00
250_R	254_A	0.865	1.00
120_I	430_S	0.864	1.00
295_Q	299_W	0.862	1.00
112_G	115_A	0.861	1.00
139_I	175_S	0.859	1.00
376_L	380_K	0.857	1.00
284_I	287_P	0.855	1.00
343_R	366_T	0.852	1.00
89_T	390_D	0.851	1.00
4_L	43_E	0.848	1.00
166_L	170_R	0.842	1.00
12_N	16_Q	0.841	1.00
246_L	301_G	0.840	1.00
328_G	334_P	0.840	1.00
163_D	167_Q	0.837	1.00
312_T	343_R	0.836	1.00
272_E	291_N	0.835	1.00
17_A	31_L	0.835	1.00
12_N	15_G	0.832	1.00
414_S	417_E	0.826	1.00
95_G	99_N	0.824	1.00
271_D	295_Q	0.823	1.00
166_L	230_A	0.820	1.00
364_E	372_R	0.819	1.00
106_Q	109_V	0.818	1.00
13_A	16_Q	0.814	1.00
7_N	47_T	0.812	1.00
252_A	257_Q	0.806	1.00
300_C	303_S	0.805	1.00
118_A	122_Y	0.805	1.00
146_G	150_F	0.804	1.00
108_E	111_R	0.804	1.00
162_D	222_R	0.804	1.00
274_S	283_F	0.803	1.00
379_Q	387_S	0.801	1.00
83_A	430_S	0.800	1.00
56_V	89_T	0.799	1.00
76_F	117_K	0.799	1.00
50_Y	394_I	0.796	1.00
113_Y	116_H	0.796	1.00
214_E	218_E	0.795	1.00
92_D	110_Y	0.794	1.00
312_T	316_T	0.794	1.00
365_L	369_M	0.794	1.00
344_M	394_I	0.794	1.00
247_D	250_R	0.791	1.00
71_S	321_Q	0.790	1.00
62_F	340_V	0.790	1.00
382_L	385_P	0.789	1.00
225_N	228_Q	0.789	1.00
303_S	361_R	0.789	1.00
102_R	106_Q	0.788	1.00
263_T	298_L	0.787	1.00
152_L	168_A	0.787	1.00
51_V	429_L	0.786	1.00
128_I	168_A	0.786	1.00
7_N	18_K	0.785	1.00
22_L	29_R	0.784	1.00
165_V	169_L	0.781	1.00
105_H	108_E	0.779	1.00
367_S	370_P	0.779	1.00
214_E	229_I	0.778	1.00
348_F	353_M	0.776	1.00
349_S	354_T	0.775	1.00
126_G	142_I	0.775	1.00
369_M	373_L	0.772	0.99
149_S	152_L	0.771	0.99
186_D	190_A	0.766	0.99
239_H	313_D	0.763	0.99
357_I	361_R	0.762	0.99
58_V	311_A	0.758	0.99
108_E	145_E	0.758	0.99
301_G	306_A	0.757	0.99
91_I	374_F	0.757	0.99
76_F	119_V	0.756	0.99
310_V	365_L	0.756	0.99
392_V	425_I	0.753	0.99
107_L	111_R	0.752	0.99
321_Q	334_P	0.751	0.99
218_E	221_A	0.751	0.99
3_V	44_I	0.751	0.99
338_P	407_L	0.748	0.99
176_G	234_P	0.745	0.99
55_G	343_R	0.745	0.99
245_G	249_L	0.743	0.99
110_Y	113_Y	0.742	0.99
100_G	110_Y	0.740	0.99
56_V	380_K	0.739	0.99
26_G	431_R	0.738	0.99
72_C	317_F	0.737	0.99
21_L	31_L	0.735	0.99
106_Q	110_Y	0.735	0.99
273_R	292_V	0.732	0.99
202_T	206_Y	0.732	0.99
114_A	118_A	0.731	0.99
342_N	345_Q	0.731	0.99
296_D	299_W	0.730	0.99
169_L	173_H	0.726	0.99
20_D	34_N	0.724	0.99
299_W	356_R	0.724	0.99
79_T	119_V	0.723	0.99
162_D	185_N	0.722	0.99
137_D	142_I	0.722	0.99
49_C	427_R	0.722	0.99
11_V	360_E	0.721	0.99
303_S	306_A	0.721	0.99
55_G	392_V	0.720	0.99
44_I	434_T	0.720	0.99
57_D	60_T	0.719	0.99
22_L	32_G	0.717	0.99
187_A	191_S	0.715	0.99
105_H	109_V	0.712	0.99
260_W	373_L	0.712	0.99
19_Q	32_G	0.711	0.99
82_A	90_I	0.711	0.99
404_H	407_L	0.710	0.99
350_S	353_M	0.710	0.99
201_L	205_R	0.709	0.99
197_I	202_T	0.708	0.99
58_V	91_I	0.708	0.99
29_R	385_P	0.706	0.99
158_Y	161_N	0.706	0.99
121_D	430_S	0.705	0.99
169_L	172_L	0.704	0.99
137_D	140_P	0.704	0.99
341_E	408_H	0.703	0.99
111_R	115_A	0.703	0.99
201_L	206_Y	0.702	0.99
227_A	258_P	0.699	0.99
339_G	342_N	0.698	0.99
9_T	16_Q	0.697	0.99
266_Q	337_L	0.695	0.99
274_S	419_F	0.695	0.99
68_I	71_S	0.695	0.99
342_N	407_L	0.694	0.99
12_N	17_A	0.692	0.99
124_F	127_V	0.692	0.99
150_F	153_Y	0.692	0.99
351_G	355_G	0.692	0.99
368_A	382_L	0.691	0.99
352_V	355_G	0.690	0.99
203_A	206_Y	0.689	0.99
338_P	413_Y	0.684	0.99
202_T	205_R	0.684	0.99
424_A	438_D	0.683	0.99
244_L	247_D	0.682	0.99
285_L	289_L	0.681	0.99
348_F	359_P	0.681	0.99
238_V	262_E	0.676	0.99
148_S	151_K	0.675	0.99
56_V	370_P	0.675	0.99
231_G	258_P	0.675	0.99
31_L	383_L	0.675	0.99
243_G	247_D	0.674	0.99
3_V	41_Y	0.673	0.99
394_I	425_I	0.670	0.99
113_Y	117_K	0.668	0.99
138_E	142_I	0.668	0.99
213_L	217_A	0.667	0.99
160_L	164_E	0.666	0.99
136_L	140_P	0.665	0.98
79_T	90_I	0.664	0.98
313_D	316_T	0.664	0.98
20_D	36_S	0.663	0.98
400_Q	425_I	0.663	0.98
146_G	151_K	0.662	0.98
83_A	119_V	0.662	0.98
380_K	390_D	0.662	0.98
91_I	376_L	0.661	0.98
145_E	148_S	0.660	0.98
62_F	92_D	0.656	0.98
344_M	362_F	0.655	0.98
140_P	175_S	0.654	0.98
281_M	333_C	0.654	0.98
184_E	188_A	0.654	0.98
237_I	240_L	0.653	0.98
49_C	397_R	0.652	0.98
345_Q	424_A	0.652	0.98
3_V	434_T	0.651	0.98
293_R	296_D	0.651	0.98
176_G	258_P	0.650	0.98
37_P	40_P	0.647	0.98
80_R	119_V	0.645	0.98
400_Q	423_G	0.642	0.98
196_F	206_Y	0.642	0.98
6_K	45_D	0.641	0.98
330_F	336_G	0.640	0.98
348_F	394_I	0.640	0.98
139_I	150_F	0.639	0.98
294_E	297_K	0.638	0.98
141_M	145_E	0.638	0.98
94_M	99_N	0.637	0.98
5_I	44_I	0.637	0.98
188_A	191_S	0.636	0.98
131_I	136_L	0.634	0.98
162_D	165_V	0.633	0.98
197_I	331_S	0.632	0.98
167_Q	171_R	0.631	0.98
312_T	317_F	0.631	0.98
287_P	290_R	0.630	0.98
103_L	106_Q	0.630	0.98
58_V	373_L	0.629	0.98
60_T	87_T	0.627	0.98
310_V	314_H	0.625	0.98
96_F	100_G	0.625	0.98
221_A	251_L	0.624	0.98
217_A	221_A	0.623	0.98
341_E	345_Q	0.622	0.98
114_A	124_F	0.622	0.98
107_L	110_Y	0.622	0.98
196_F	208_A	0.621	0.98
347_L	351_G	0.619	0.98
95_G	100_G	0.619	0.98
141_M	144_E	0.619	0.98
310_V	316_T	0.618	0.98
72_C	321_Q	0.617	0.98
96_F	99_N	0.617	0.98
121_D	124_F	0.615	0.97
44_I	393_I	0.613	0.97
162_D	166_L	0.609	0.97
217_A	248_Y	0.609	0.97
146_G	149_S	0.608	0.97
406_H	417_E	0.607	0.97
15_G	384_A	0.607	0.97
427_R	436_F	0.607	0.97
42_E	427_R	0.607	0.97
330_F	333_C	0.606	0.97
329_D	333_C	0.605	0.97
9_T	17_A	0.605	0.97
82_A	340_V	0.602	0.97
125_H	180_T	0.602	0.97
220_I	224_I	0.600	0.97
180_T	188_A	0.600	0.97
348_F	396_P	0.600	0.97
205_R	209_L	0.598	0.97
345_Q	425_I	0.595	0.97
125_H	128_I	0.595	0.97
240_L	307_I	0.594	0.97
196_F	200_G	0.592	0.97
213_L	291_N	0.592	0.97
299_W	351_G	0.591	0.97
280_G	283_F	0.587	0.97
350_S	419_F	0.587	0.97
59_H	239_H	0.584	0.97
170_R	195_E	0.584	0.97
68_I	72_C	0.584	0.97
328_G	331_S	0.584	0.97
218_E	222_R	0.583	0.97
344_M	347_L	0.583	0.97
220_I	240_L	0.581	0.96
6_K	35_I	0.580	0.96
160_L	165_V	0.578	0.96
375_G	379_Q	0.578	0.96
422_Q	425_I	0.578	0.96
348_F	362_F	0.578	0.96
252_A	256_H	0.577	0.96
22_L	34_N	0.577	0.96
280_G	288_P	0.577	0.96
180_T	374_F	0.577	0.96
65_D	113_Y	0.576	0.96
344_M	392_V	0.576	0.96
245_G	248_Y	0.575	0.96
237_I	249_L	0.575	0.96
343_R	347_L	0.575	0.96
425_I	428_T	0.575	0.96
34_N	37_P	0.574	0.96
249_L	252_A	0.574	0.96
196_F	199_A	0.573	0.96
101_C	106_Q	0.572	0.96
89_T	371_A	0.572	0.96
52_F	367_S	0.571	0.96
353_M	397_R	0.570	0.96
281_M	284_I	0.569	0.96
14_D	384_A	0.569	0.96
152_L	157_Q	0.569	0.96
319_M	327_K	0.568	0.96
99_N	102_R	0.567	0.96
89_T	121_D	0.566	0.96
351_G	356_R	0.566	0.96
84_C	341_E	0.566	0.96
162_D	187_A	0.566	0.96
407_L	417_E	0.563	0.96
143_V	150_F	0.563	0.96
81_A	340_V	0.559	0.96
65_D	68_I	0.557	0.96
51_V	383_L	0.556	0.96
197_I	203_A	0.556	0.96
22_L	37_P	0.554	0.95
14_D	368_A	0.553	0.95
346_L	421_C	0.552	0.95
412_D	423_G	0.552	0.95
13_A	368_A	0.552	0.95
181_V	223_M	0.550	0.95
390_D	430_S	0.548	0.95
351_G	357_I	0.545	0.95
7_N	20_D	0.542	0.95
185_N	222_R	0.542	0.95
68_I	97_G	0.541	0.95
103_L	108_E	0.540	0.95
204_P	207_H	0.538	0.95
10_V	31_L	0.537	0.95
253_R	306_A	0.536	0.95
303_S	356_R	0.536	0.95
316_T	321_Q	0.535	0.94
219_A	222_R	0.534	0.94
234_P	373_L	0.534	0.94
72_C	318_S	0.534	0.94
9_T	397_R	0.533	0.94
99_N	103_L	0.533	0.94
296_D	356_R	0.532	0.94
9_T	47_T	0.531	0.94
269_L	350_S	0.531	0.94
30_Q	34_N	0.529	0.94
148_S	169_L	0.529	0.94
246_L	307_I	0.529	0.94
328_G	333_C	0.528	0.94
279_D	282_K	0.528	0.94
346_L	350_S	0.528	0.94
119_V	124_F	0.527	0.94
63_N	72_C	0.527	0.94
55_G	367_S	0.526	0.94
195_E	211_R	0.525	0.94
282_K	319_M	0.525	0.94
246_L	261_V	0.525	0.94
375_G	378_P	0.525	0.94
136_L	146_G	0.525	0.94
9_T	19_Q	0.524	0.94
142_I	145_E	0.522	0.94
60_T	340_V	0.522	0.94
222_R	225_N	0.522	0.94
207_H	286_S	0.522	0.94
94_M	100_G	0.521	0.94
263_T	268_L	0.519	0.94
89_T	380_K	0.519	0.94
13_A	360_E	0.519	0.94
239_H	262_E	0.519	0.94
63_N	317_F	0.518	0.93
246_L	250_R	0.518	0.93
162_D	169_L	0.518	0.93
144_E	175_S	0.518	0.93
213_L	242_N	0.518	0.93
337_L	415_P	0.517	0.93
407_L	412_D	0.516	0.93
240_L	261_V	0.516	0.93
147_L	150_F	0.515	0.93
152_L	156_Y	0.515	0.93
314_H	317_F	0.515	0.93
352_V	359_P	0.513	0.93
268_L	347_L	0.513	0.93
88_T	390_D	0.512	0.93
366_T	370_P	0.511	0.93
172_L	233_A	0.511	0.93
327_K	332_R	0.511	0.93
168_A	179_T	0.510	0.93
90_I	120_I	0.510	0.93
165_V	168_A	0.510	0.93
196_F	209_L	0.509	0.93
136_L	139_I	0.509	0.93
223_M	227_A	0.508	0.93
270_L	415_P	0.506	0.93
135_I	138_E	0.505	0.93
121_D	390_D	0.504	0.93
139_I	143_V	0.504	0.93
32_G	37_P	0.503	0.92
311_A	314_H	0.503	0.92
294_E	301_G	0.503	0.92
158_Y	165_V	0.503	0.92
4_L	35_I	0.502	0.92
197_I	200_G	0.501	0.92
317_F	321_Q	0.501	0.92
119_V	125_H	0.501	0.92
344_M	366_T	0.501	0.92
179_T	191_S	0.500	0.92

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3dc8A	3	0.9761	100	0.227	Contact Map
2ftyA	3	0.9957	100	0.239	Contact Map
4lcqA	3	0.9913	100	0.24	Contact Map
2ftwA	3	0.9892	100	0.255	Contact Map
4bknA	3	0.9892	100	0.257	Contact Map
1gkpA	4	0.9848	100	0.258	Contact Map
2vm8A	3	0.987	100	0.261	Contact Map
3sfwA	3	0.9848	100	0.265	Contact Map
1nfgA	3	0.9805	100	0.273	Contact Map
1gkrA	3	0.9566	100	0.28	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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