YGEV - ECOLI - GREMLIN Contacts

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YGEV - Uncharacterized sigma-54-dependent transcriptional regulator YgeV

UniProt:	Q46802	Sequences: MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAGTGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISKIFATMIDNMDQGVLVVDDENRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREALSRHNSKKQVADELGIGIATLYRKIKKYELLNT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13052
Length:	592 (535)
Sequences:	1533 (1275)
Seq/√Len:	55.1

ECOLI - YGEV DHAR HYFR FHLA RTCR TYRR NORR PRPR NTRC GLRR ATOC ZRAR
BACSU - ACOR YQIR ROCR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
346_K	355_N	4.700	1.00
301_E	445_R	4.681	1.00
420_F	425_K	4.503	1.00
330_A	383_A	4.087	1.00
563_H	572_E	3.772	1.00
419_Q	423_E	3.611	1.00
362_Q	396_P	3.594	1.00
552_E	583_K	3.416	1.00
416_N	419_Q	3.415	1.00
346_K	353_S	3.394	1.00
559_A	569_V	3.362	1.00
319_R	406_D	3.276	1.00
477_V	481_L	3.209	1.00
461_L	494_S	3.158	1.00
575_I	580_L	3.074	1.00
141_S	144_F	2.937	1.00
345_V	399_A	2.929	1.00
452_E	482_R	2.927	1.00
141_S	145_V	2.799	1.00
338_E	384_K	2.689	1.00
553_K	557_R	2.671	1.00
334_E	380_M	2.631	1.00
456_H	478_V	2.630	1.00
370_F	412_A	2.545	1.00
269_I	312_A	2.499	1.00
474_A	511_D	2.496	1.00
393_E	402_P	2.438	1.00
344_Y	356_G	2.438	1.00
563_H	569_V	2.429	1.00
133_F	136_Y	2.394	1.00
549_E	586_K	2.376	1.00
477_V	510_I	2.315	1.00
395_L	402_P	2.309	1.00
59_N	64_R	2.307	1.00
307_E	387_R	2.304	1.00
177_D	181_R	2.303	1.00
236_G	239_H	2.298	1.00
282_L	309_V	2.269	1.00
130_L	141_S	2.268	1.00
64_R	68_E	2.264	1.00
562_R	572_E	2.260	1.00
137_V	140_I	2.260	1.00
98_F	114_S	2.243	1.00
393_E	404_Q	2.226	1.00
282_L	439_I	2.220	1.00
415_Q	420_F	2.215	1.00
394_I	405_V	2.152	1.00
476_D	512_S	2.098	1.00
346_K	354_A	2.066	1.00
59_N	68_E	2.027	1.00
137_V	145_V	2.008	1.00
130_L	145_V	1.968	1.00
360_L	363_A	1.939	1.00
474_A	477_V	1.936	1.00
311_R	315_K	1.933	1.00
480_I	512_S	1.924	1.00
73_K	80_F	1.914	1.00
132_E	140_I	1.912	1.00
140_I	145_V	1.910	1.00
130_L	137_V	1.896	1.00
584_I	589_L	1.894	1.00
105_L	108_R	1.878	0.99
74_V	81_D	1.850	0.99
452_E	478_V	1.838	0.99
454_L	458_F	1.814	0.99
136_Y	141_S	1.800	0.99
129_N	133_F	1.797	0.99
422_A	428_E	1.793	0.99
130_L	140_I	1.789	0.99
361_I	369_L	1.782	0.99
140_I	144_F	1.773	0.99
473_I	478_V	1.769	0.99
361_I	405_V	1.736	0.99
142_T	145_V	1.730	0.99
59_N	62_L	1.727	0.99
286_I	309_V	1.724	0.99
330_A	376_D	1.719	0.99
556_I	580_L	1.713	0.99
126_I	129_N	1.712	0.99
369_L	409_I	1.711	0.99
555_M	559_A	1.702	0.99
291_P	318_G	1.700	0.99
73_K	76_T	1.698	0.99
420_F	423_E	1.697	0.99
48_Y	51_F	1.696	0.99
566_K	577_I	1.678	0.99
451_I	455_V	1.673	0.99
337_L	381_L	1.671	0.99
274_G	279_M	1.661	0.99
556_I	569_V	1.653	0.99
97_A	117_A	1.645	0.99
70_K	73_K	1.633	0.99
272_L	279_M	1.623	0.98
348_A	397_I	1.617	0.98
68_E	71_T	1.607	0.98
399_A	403_I	1.606	0.98
500_L	510_I	1.597	0.98
552_E	556_I	1.596	0.98
74_V	80_F	1.583	0.98
319_R	407_I	1.580	0.98
64_R	69_T	1.574	0.98
421_I	424_G	1.573	0.98
159_S	162_F	1.563	0.98
98_F	116_I	1.546	0.98
62_L	70_K	1.546	0.98
353_S	357_K	1.533	0.98
267_P	311_R	1.519	0.98
389_I	409_I	1.511	0.98
128_D	131_R	1.510	0.98
376_D	414_N	1.508	0.98
296_V	313_I	1.507	0.98
136_Y	140_I	1.506	0.98
390_E	494_S	1.503	0.98
129_N	132_E	1.499	0.97
478_V	482_R	1.491	0.97
137_V	144_F	1.480	0.97
275_E	453_L	1.480	0.97
473_I	497_M	1.479	0.97
73_K	81_D	1.476	0.97
136_Y	145_V	1.469	0.97
307_E	391_A	1.464	0.97
583_K	587_Y	1.464	0.97
143_I	146_S	1.457	0.97
548_L	555_M	1.456	0.97
388_A	391_A	1.456	0.97
417_L	426_F	1.455	0.97
294_S	502_N	1.443	0.97
136_Y	144_F	1.433	0.97
366_T	406_D	1.431	0.97
224_I	227_W	1.431	0.97
59_N	70_K	1.424	0.97
62_L	73_K	1.416	0.96
551_M	555_M	1.412	0.96
496_L	500_L	1.406	0.96
299_V	438_P	1.403	0.96
484_H	487_P	1.392	0.96
294_S	498_E	1.389	0.96
59_N	71_T	1.384	0.96
131_R	136_Y	1.378	0.96
548_L	583_K	1.374	0.96
361_I	407_I	1.367	0.96
64_R	70_K	1.366	0.96
459_L	501_V	1.357	0.95
132_E	141_S	1.357	0.95
135_D	144_F	1.357	0.95
554_Q	558_E	1.355	0.95
568_Q	571_D	1.355	0.95
132_E	135_D	1.354	0.95
566_K	581_Y	1.352	0.95
474_A	509_V	1.350	0.95
418_A	518_N	1.349	0.95
136_Y	143_I	1.340	0.95
74_V	78_S	1.326	0.95
310_A	324_F	1.323	0.95
304_T	441_L	1.322	0.95
129_N	136_Y	1.319	0.95
444_L	493_L	1.316	0.95
477_V	519_L	1.315	0.95
224_I	233_L	1.309	0.94
557_R	589_L	1.307	0.94
62_L	68_E	1.305	0.94
556_I	583_K	1.304	0.94
64_R	71_T	1.301	0.94
188_T	191_K	1.295	0.94
132_E	136_Y	1.292	0.94
172_G	186_N	1.291	0.94
298_V	309_V	1.289	0.94
557_R	561_S	1.283	0.94
289_I	437_I	1.282	0.94
279_M	282_L	1.280	0.94
568_Q	572_E	1.271	0.93
477_V	512_S	1.267	0.93
283_K	309_V	1.265	0.93
360_L	395_L	1.259	0.93
130_L	134_S	1.258	0.93
559_A	563_H	1.254	0.93
375_G	413_T	1.245	0.93
455_V	473_I	1.245	0.93
75_V	80_F	1.243	0.93
440_T	446_E	1.243	0.93
299_V	413_T	1.240	0.93
59_N	69_T	1.235	0.92
283_K	287_S	1.232	0.92
387_R	391_A	1.232	0.92
185_V	189_A	1.231	0.92
452_E	455_V	1.230	0.92
476_D	511_D	1.230	0.92
68_E	88_D	1.229	0.92
130_L	144_F	1.227	0.92
73_K	83_L	1.227	0.92
134_S	144_F	1.221	0.92
579_T	582_R	1.220	0.92
134_S	140_I	1.219	0.92
429_D	433_R	1.218	0.92
128_D	136_Y	1.216	0.92
458_F	497_M	1.212	0.92
455_V	497_M	1.209	0.92
132_E	143_I	1.201	0.91
128_D	140_I	1.189	0.91
75_V	78_S	1.189	0.91
567_K	577_I	1.176	0.91
75_V	83_L	1.175	0.90
472_G	509_V	1.171	0.90
270_E	287_S	1.171	0.90
334_E	338_E	1.168	0.90
392_R	404_Q	1.167	0.90
369_L	405_V	1.164	0.90
39_L	43_A	1.161	0.90
41_R	44_G	1.156	0.90
516_P	519_L	1.155	0.90
78_S	104_I	1.153	0.90
479_E	483_K	1.151	0.90
386_L	429_D	1.149	0.89
292_S	502_N	1.143	0.89
361_I	388_A	1.141	0.89
307_E	390_E	1.139	0.89
507_G	514_L	1.138	0.89
136_Y	146_S	1.137	0.89
142_T	146_S	1.135	0.89
290_A	408_R	1.133	0.89
365_N	406_D	1.129	0.89
73_K	78_S	1.118	0.88
288_R	506_S	1.118	0.88
548_L	551_M	1.116	0.88
473_I	510_I	1.116	0.88
40_C	61_R	1.115	0.88
104_I	109_C	1.106	0.88
43_A	47_A	1.101	0.87
174_L	189_A	1.101	0.87
62_L	72_E	1.098	0.87
373_E	412_A	1.096	0.87
71_T	100_G	1.095	0.87
411_S	434_L	1.092	0.87
471_P	501_V	1.090	0.87
61_R	67_L	1.090	0.87
448_Q	451_I	1.085	0.87
132_E	139_H	1.080	0.86
433_R	491_R	1.079	0.86
229_D	232_E	1.078	0.86
348_A	352_A	1.075	0.86
560_L	569_V	1.070	0.86
63_L	66_V	1.068	0.86
93_C	116_I	1.066	0.86
339_S	349_F	1.066	0.86
335_Q	338_E	1.063	0.85
333_P	338_E	1.063	0.85
372_D	491_R	1.062	0.85
62_L	71_T	1.061	0.85
375_G	414_N	1.060	0.85
350_T	433_R	1.057	0.85
301_E	443_P	1.057	0.85
129_N	143_I	1.056	0.85
244_R	247_F	1.052	0.85
309_V	441_L	1.050	0.85
365_N	405_V	1.050	0.85
443_P	446_E	1.042	0.84
516_P	520_L	1.042	0.84
88_D	98_F	1.041	0.84
386_L	427_R	1.041	0.84
36_D	39_L	1.036	0.84
271_Q	315_K	1.031	0.84
475_P	479_E	1.031	0.84
278_V	446_E	1.029	0.84
90_K	93_C	1.027	0.83
134_S	145_V	1.027	0.83
304_T	409_I	1.023	0.83
374_I	377_M	1.017	0.83
427_R	491_R	1.017	0.83
312_A	316_L	1.012	0.82
298_V	441_L	1.010	0.82
140_I	143_I	1.009	0.82
196_V	199_N	1.008	0.82
137_V	141_S	1.001	0.82
352_A	375_G	0.996	0.81
337_L	384_K	0.996	0.81
71_T	74_V	0.993	0.81
67_L	90_K	0.988	0.81
93_C	96_K	0.986	0.81
189_A	193_L	0.984	0.81
190_L	197_Q	0.979	0.80
462_H	497_M	0.977	0.80
577_I	581_Y	0.973	0.80
279_M	283_K	0.966	0.79
174_L	182_V	0.964	0.79
576_G	581_Y	0.962	0.79
419_Q	422_A	0.956	0.79
373_E	429_D	0.955	0.79
448_Q	485_R	0.955	0.79
326_A	387_R	0.952	0.78
143_I	147_K	0.949	0.78
387_R	429_D	0.949	0.78
59_N	63_L	0.949	0.78
560_L	584_I	0.947	0.78
295_S	411_S	0.946	0.78
344_Y	349_F	0.944	0.78
126_I	130_L	0.944	0.78
48_Y	52_L	0.939	0.77
132_E	146_S	0.939	0.77
409_I	434_L	0.938	0.77
352_A	433_R	0.937	0.77
74_V	77_Q	0.937	0.77
126_I	135_D	0.932	0.77
268_H	271_Q	0.931	0.77
185_V	200_I	0.929	0.77
269_I	272_L	0.928	0.77
275_E	280_R	0.928	0.77
70_K	88_D	0.926	0.76
547_A	550_E	0.925	0.76
126_I	133_F	0.925	0.76
484_H	519_L	0.923	0.76
333_P	336_L	0.922	0.76
59_N	88_D	0.921	0.76
394_I	404_Q	0.918	0.76
334_E	384_K	0.916	0.76
363_A	399_A	0.916	0.76
128_D	133_F	0.911	0.75
62_L	69_T	0.911	0.75
427_R	433_R	0.908	0.75
307_E	326_A	0.906	0.75
499_Y	502_N	0.906	0.75
548_L	552_E	0.904	0.75
372_D	412_A	0.903	0.75
241_I	248_L	0.901	0.75
272_L	312_A	0.896	0.74
569_V	578_A	0.895	0.74
235_I	241_I	0.894	0.74
500_L	514_L	0.890	0.74
477_V	516_P	0.890	0.74
160_K	163_A	0.889	0.74
504_V	514_L	0.889	0.74
130_L	136_Y	0.888	0.73
78_S	81_D	0.886	0.73
229_D	233_L	0.875	0.72
135_D	141_S	0.866	0.72
307_E	414_N	0.865	0.71
364_A	407_I	0.865	0.71
60_S	64_R	0.864	0.71
75_V	81_D	0.864	0.71
500_L	504_V	0.861	0.71
578_A	582_R	0.861	0.71
466_L	502_N	0.858	0.71
459_L	473_I	0.856	0.71
567_K	578_A	0.856	0.71
133_F	140_I	0.856	0.71
552_E	587_Y	0.852	0.70
484_H	518_N	0.850	0.70
80_F	83_L	0.850	0.70
128_D	132_E	0.849	0.70
63_L	70_K	0.848	0.70
350_T	429_D	0.845	0.70
64_R	73_K	0.844	0.70
550_E	554_Q	0.844	0.70
209_P	215_N	0.844	0.70
78_S	82_P	0.844	0.70
567_K	571_D	0.843	0.69
477_V	511_D	0.840	0.69
134_S	141_S	0.838	0.69
132_E	147_K	0.837	0.69
130_L	133_F	0.835	0.69
575_I	583_K	0.833	0.69
234_I	237_Q	0.832	0.68
338_E	380_M	0.831	0.68
68_E	89_S	0.831	0.68
576_G	582_R	0.830	0.68
161_I	492_E	0.828	0.68
569_V	572_E	0.826	0.68
39_L	42_V	0.825	0.68
578_A	581_Y	0.825	0.68
74_V	82_P	0.823	0.68
313_I	360_L	0.822	0.68
290_A	313_I	0.821	0.67
131_R	143_I	0.820	0.67
336_L	427_R	0.820	0.67
134_S	142_T	0.820	0.67
56_L	96_K	0.818	0.67
269_I	283_K	0.815	0.67
273_V	457_Y	0.814	0.67
173_V	285_L	0.813	0.67
328_N	386_L	0.809	0.66
418_A	422_A	0.809	0.66
463_T	471_P	0.809	0.66
236_G	240_N	0.809	0.66
484_H	492_E	0.809	0.66
224_I	229_D	0.808	0.66
375_G	415_Q	0.808	0.66
77_Q	80_F	0.806	0.66
75_V	86_G	0.805	0.66
559_A	575_I	0.803	0.66
68_E	72_E	0.802	0.66
441_L	490_L	0.801	0.66
49_G	52_L	0.799	0.65
135_D	143_I	0.798	0.65
349_F	352_A	0.797	0.65
61_R	66_V	0.797	0.65
376_D	415_Q	0.795	0.65
242_Q	245_Q	0.795	0.65
479_E	482_R	0.794	0.65
226_S	229_D	0.794	0.65
362_Q	403_I	0.793	0.65
330_A	338_E	0.788	0.64
41_R	70_K	0.786	0.64
80_F	84_C	0.786	0.64
344_Y	429_D	0.785	0.64
287_S	316_L	0.784	0.64
84_C	87_C	0.784	0.64
333_P	337_L	0.782	0.64
344_Y	353_S	0.782	0.64
399_A	402_P	0.781	0.64
228_D	233_L	0.779	0.63
71_T	88_D	0.778	0.63
265_D	311_R	0.778	0.63
135_D	142_T	0.778	0.63
176_V	182_V	0.777	0.63
272_L	441_L	0.777	0.63
74_V	83_L	0.776	0.63
426_F	430_L	0.776	0.63
373_E	433_R	0.775	0.63
387_R	427_R	0.772	0.63
375_G	412_A	0.771	0.63
377_M	548_L	0.767	0.62
471_P	508_E	0.767	0.62
510_I	515_L	0.766	0.62
429_D	491_R	0.763	0.62
328_N	350_T	0.762	0.62
210_L	215_N	0.760	0.61
64_R	72_E	0.758	0.61
417_L	424_G	0.758	0.61
223_H	227_W	0.756	0.61
76_T	80_F	0.756	0.61
74_V	85_E	0.755	0.61
159_S	163_A	0.752	0.61
554_Q	557_R	0.749	0.60
133_F	146_S	0.746	0.60
152_Q	155_G	0.746	0.60
272_L	308_V	0.744	0.60
41_R	45_T	0.744	0.60
339_S	433_R	0.743	0.60
269_I	286_I	0.743	0.60
88_D	96_K	0.742	0.60
336_L	348_A	0.742	0.60
558_E	562_R	0.741	0.59
75_V	112_V	0.740	0.59
97_A	116_I	0.739	0.59
421_I	428_E	0.738	0.59
81_D	86_G	0.736	0.59
140_I	146_S	0.735	0.59
404_Q	434_L	0.734	0.59
507_G	511_D	0.734	0.59
169_M	302_S	0.727	0.58
339_S	429_D	0.727	0.58
64_R	88_D	0.725	0.58
398_G	433_R	0.724	0.58
132_E	145_V	0.723	0.58
330_A	384_K	0.721	0.57
36_D	43_A	0.721	0.57
375_G	433_R	0.721	0.57
128_D	144_F	0.720	0.57
40_C	43_A	0.719	0.57
563_H	568_Q	0.719	0.57
339_S	491_R	0.718	0.57
411_S	492_E	0.716	0.57
249_M	252_H	0.715	0.57
294_S	436_V	0.715	0.57
83_L	86_G	0.715	0.57
82_P	99_L	0.715	0.57
265_D	315_K	0.712	0.56
289_I	361_I	0.710	0.56
137_V	146_S	0.710	0.56
545_G	559_A	0.709	0.56
336_L	339_S	0.707	0.56
328_N	356_G	0.707	0.56
36_D	46_G	0.707	0.56
182_V	207_F	0.705	0.56
556_I	589_L	0.705	0.56
289_I	577_I	0.704	0.56
350_T	373_E	0.703	0.55
386_L	433_R	0.700	0.55
131_R	134_S	0.699	0.55
80_F	85_E	0.698	0.55
113_I	337_L	0.698	0.55
455_V	482_R	0.698	0.55
286_I	439_I	0.697	0.55
72_E	93_C	0.697	0.55
59_N	73_K	0.697	0.55
344_Y	350_T	0.696	0.55
41_R	72_E	0.695	0.55
249_M	254_S	0.694	0.55
387_R	414_N	0.690	0.54
302_S	411_S	0.690	0.54
222_Q	227_W	0.689	0.54
129_N	145_V	0.688	0.54
144_F	147_K	0.687	0.54
68_E	80_F	0.686	0.54
418_A	521_N	0.686	0.54
356_G	394_I	0.685	0.54
545_G	550_E	0.685	0.54
276_C	436_V	0.683	0.53
73_K	82_P	0.682	0.53
350_T	368_T	0.681	0.53
314_H	368_T	0.679	0.53
248_L	258_F	0.675	0.52
186_N	319_R	0.675	0.52
359_G	373_E	0.675	0.52
70_K	74_V	0.675	0.52
282_L	286_I	0.674	0.52
100_G	114_S	0.671	0.52
398_G	429_D	0.671	0.52
44_G	53_G	0.669	0.52
336_L	398_G	0.668	0.52
566_K	571_D	0.665	0.51
336_L	350_T	0.664	0.51
99_L	492_E	0.664	0.51
344_Y	375_G	0.663	0.51
500_L	515_L	0.663	0.51
462_H	501_V	0.663	0.51
299_V	440_T	0.662	0.51
269_I	273_V	0.662	0.51
135_D	138_R	0.662	0.51
365_N	394_I	0.661	0.51
352_A	429_D	0.660	0.51
90_K	94_R	0.660	0.51
84_C	93_C	0.660	0.51
358_T	400_S	0.656	0.50
307_E	427_R	0.656	0.50
322_K	366_T	0.656	0.50
246_L	249_M	0.655	0.50
55_Q	67_L	0.655	0.50
267_P	271_Q	0.654	0.50
88_D	114_S	0.654	0.50
498_E	502_N	0.653	0.50
352_A	427_R	0.653	0.50
290_A	492_E	0.652	0.50
126_I	136_Y	0.652	0.50
138_R	142_T	0.651	0.50
345_V	413_T	0.651	0.50
36_D	41_R	0.650	0.50
462_H	498_E	0.650	0.50
240_N	247_F	0.650	0.50
267_P	270_E	0.649	0.50
375_G	429_D	0.647	0.49
67_L	93_C	0.647	0.49
289_I	439_I	0.643	0.49
454_L	457_Y	0.643	0.49
349_F	373_E	0.643	0.49
46_G	56_L	0.642	0.49
373_E	427_R	0.640	0.49
373_E	398_G	0.639	0.49
407_I	435_N	0.639	0.49
338_E	582_R	0.638	0.48
452_E	456_H	0.638	0.48
196_V	526_E	0.635	0.48
387_R	491_R	0.635	0.48
169_M	173_V	0.635	0.48
54_R	67_L	0.635	0.48
54_R	96_K	0.635	0.48
135_D	145_V	0.634	0.48
128_D	143_I	0.634	0.48
342_F	359_G	0.634	0.48
565_S	584_I	0.633	0.48
129_N	142_T	0.633	0.48
506_S	514_L	0.632	0.48
73_K	77_Q	0.632	0.48
77_Q	85_E	0.627	0.47
37_E	78_S	0.627	0.47
132_E	144_F	0.627	0.47
307_E	373_E	0.627	0.47
363_A	400_S	0.626	0.47
359_G	433_R	0.626	0.47
101_T	137_V	0.626	0.47
333_P	376_D	0.624	0.47
439_I	570_A	0.623	0.47
346_K	356_G	0.622	0.47
336_L	491_R	0.622	0.47
339_S	344_Y	0.622	0.47
84_C	97_A	0.621	0.47
398_G	427_R	0.618	0.46
350_T	386_L	0.618	0.46
349_F	414_N	0.618	0.46
100_G	112_V	0.617	0.46
547_A	551_M	0.616	0.46
70_K	89_S	0.616	0.46
328_N	432_Y	0.614	0.46
274_G	283_K	0.613	0.46
250_A	253_Q	0.613	0.46
248_L	252_H	0.613	0.46
267_P	315_K	0.613	0.46
376_D	427_R	0.612	0.46
415_Q	431_F	0.612	0.46
64_R	89_S	0.612	0.46
336_L	344_Y	0.611	0.46
155_G	158_I	0.611	0.46
42_V	58_G	0.610	0.45
360_L	396_P	0.608	0.45
250_A	254_S	0.606	0.45
158_I	173_V	0.605	0.45
78_S	83_L	0.604	0.45
302_S	433_R	0.604	0.45
157_N	160_K	0.604	0.45
368_T	500_L	0.604	0.45
312_A	500_L	0.603	0.45
41_R	47_A	0.603	0.45
276_C	279_M	0.602	0.45
336_L	373_E	0.602	0.45
63_L	68_E	0.602	0.45
476_D	480_I	0.602	0.45
36_D	42_V	0.601	0.45
299_V	414_N	0.600	0.44
294_S	466_L	0.599	0.44
93_C	118_V	0.599	0.44
126_I	141_S	0.599	0.44
238_L	241_I	0.598	0.44
136_Y	142_T	0.598	0.44
51_F	60_S	0.598	0.44
243_G	246_L	0.598	0.44
383_A	409_I	0.597	0.44
349_F	375_G	0.596	0.44
85_E	94_R	0.596	0.44
339_S	350_T	0.596	0.44
556_I	575_I	0.596	0.44
580_L	583_K	0.594	0.44
359_G	398_G	0.593	0.44
59_N	80_F	0.593	0.44
499_Y	503_V	0.592	0.44
128_D	134_S	0.591	0.43
331_A	338_E	0.591	0.43
141_S	146_S	0.591	0.43
59_N	89_S	0.590	0.43
351_G	372_D	0.590	0.43
332_I	339_S	0.590	0.43
548_L	556_I	0.589	0.43
69_T	77_Q	0.589	0.43
336_L	387_R	0.589	0.43
342_F	398_G	0.588	0.43
222_Q	225_V	0.587	0.43
350_T	375_G	0.587	0.43
82_P	86_G	0.587	0.43
553_K	583_K	0.585	0.43
344_Y	351_G	0.585	0.43
372_D	387_R	0.584	0.43
283_K	286_I	0.583	0.43
377_M	383_A	0.583	0.43
93_C	113_I	0.582	0.43
129_N	140_I	0.581	0.42
344_Y	373_E	0.581	0.42
555_M	558_E	0.581	0.42
398_G	491_R	0.580	0.42
435_N	495_N	0.580	0.42
351_G	433_R	0.580	0.42
319_R	322_K	0.579	0.42
349_F	433_R	0.579	0.42
252_H	255_H	0.579	0.42
336_L	375_G	0.578	0.42
289_I	360_L	0.578	0.42
41_R	51_F	0.575	0.42
251_F	256_T	0.575	0.42
477_V	500_L	0.575	0.42
235_I	238_L	0.574	0.42
378_P	383_A	0.574	0.42
359_G	429_D	0.573	0.42
60_S	63_L	0.573	0.42
342_F	433_R	0.573	0.42
135_D	140_I	0.572	0.41
111_G	575_I	0.571	0.41
208_R	211_T	0.570	0.41
340_E	344_Y	0.569	0.41
336_L	349_F	0.569	0.41
173_V	186_N	0.569	0.41
70_K	83_L	0.568	0.41
336_L	429_D	0.568	0.41
342_F	373_E	0.567	0.41
56_L	62_L	0.567	0.41
166_I	565_S	0.567	0.41
336_L	414_N	0.566	0.41
454_L	573_L	0.565	0.41
414_N	433_R	0.565	0.41
328_N	429_D	0.565	0.41
307_E	491_R	0.565	0.41
134_S	137_V	0.564	0.41
193_L	315_K	0.564	0.41
345_V	400_S	0.564	0.41
243_G	248_L	0.563	0.41
223_H	247_F	0.562	0.40
274_G	298_V	0.561	0.40
352_A	373_E	0.559	0.40
358_T	399_A	0.559	0.40
328_N	336_L	0.558	0.40
392_R	406_D	0.558	0.40
279_M	309_V	0.557	0.40
333_P	375_G	0.556	0.40
210_L	216_F	0.556	0.40
352_A	397_I	0.556	0.40
342_F	429_D	0.555	0.40
44_G	48_Y	0.555	0.40
351_G	491_R	0.554	0.40
130_L	143_I	0.554	0.40
285_L	571_D	0.553	0.40
333_P	399_A	0.553	0.40
286_I	316_L	0.553	0.40
344_Y	433_R	0.553	0.40
129_N	135_D	0.552	0.39
103_V	111_G	0.552	0.39
556_I	573_L	0.551	0.39
59_N	74_V	0.551	0.39
386_L	491_R	0.551	0.39
370_F	388_A	0.550	0.39
56_L	59_N	0.550	0.39
336_L	351_G	0.550	0.39
339_S	386_L	0.550	0.39
68_E	74_V	0.550	0.39
389_I	584_I	0.549	0.39
349_F	429_D	0.549	0.39
443_P	460_H	0.548	0.39
39_L	46_G	0.548	0.39
307_E	429_D	0.547	0.39
40_C	56_L	0.547	0.39
73_K	85_E	0.545	0.39
374_I	405_V	0.545	0.39
62_L	67_L	0.543	0.38
372_D	427_R	0.543	0.38
372_D	433_R	0.542	0.38
68_E	73_K	0.542	0.38
268_H	311_R	0.542	0.38
347_G	373_E	0.541	0.38
294_S	437_I	0.540	0.38
574_G	577_I	0.540	0.38
38_N	52_L	0.540	0.38
55_Q	90_K	0.540	0.38
254_S	257_S	0.540	0.38
292_S	498_E	0.540	0.38
481_L	519_L	0.539	0.38
319_R	441_L	0.539	0.38
126_I	140_I	0.539	0.38
412_A	429_D	0.539	0.38
46_G	71_T	0.539	0.38
134_S	146_S	0.538	0.38
68_E	87_C	0.537	0.38
390_E	411_S	0.536	0.38
322_K	362_Q	0.536	0.38
235_I	247_F	0.536	0.38
277_R	431_F	0.535	0.38
326_A	394_I	0.533	0.37
60_S	73_K	0.533	0.37
47_A	51_F	0.532	0.37
129_N	137_V	0.532	0.37
240_N	248_L	0.532	0.37
59_N	72_E	0.531	0.37
217_T	220_H	0.531	0.37
339_S	398_G	0.530	0.37
175_V	366_T	0.530	0.37
357_K	413_T	0.528	0.37
373_E	414_N	0.528	0.37
458_F	494_S	0.527	0.37
304_T	324_F	0.526	0.37
326_A	356_G	0.525	0.37
302_S	376_D	0.525	0.37
56_L	73_K	0.524	0.37
336_L	433_R	0.524	0.37
361_I	492_E	0.524	0.37
387_R	433_R	0.523	0.36
344_Y	412_A	0.522	0.36
237_Q	241_I	0.520	0.36
336_L	352_A	0.520	0.36
370_F	491_R	0.518	0.36
234_I	327_I	0.518	0.36
39_L	70_K	0.518	0.36
132_E	137_V	0.518	0.36
477_V	514_L	0.518	0.36
62_L	88_D	0.517	0.36
376_D	433_R	0.517	0.36
77_Q	335_Q	0.517	0.36
412_A	427_R	0.516	0.36
347_G	350_T	0.515	0.36
245_Q	248_L	0.515	0.36
133_F	137_V	0.515	0.36
248_L	251_F	0.514	0.36
68_E	114_S	0.514	0.36
126_I	145_V	0.513	0.35
307_E	386_L	0.513	0.35
436_V	498_E	0.513	0.35
281_Q	285_L	0.512	0.35
298_V	439_I	0.511	0.35
448_Q	452_E	0.511	0.35
272_L	309_V	0.511	0.35
273_V	436_V	0.511	0.35
302_S	427_R	0.511	0.35
289_I	378_P	0.510	0.35
243_G	365_N	0.510	0.35
363_A	396_P	0.508	0.35
83_L	88_D	0.507	0.35
213_E	219_G	0.507	0.35
208_R	212_F	0.507	0.35
232_E	589_L	0.506	0.35
307_E	433_R	0.506	0.35
334_E	582_R	0.506	0.35
333_P	384_K	0.505	0.35
496_L	571_D	0.505	0.35
328_N	388_A	0.504	0.35
267_P	287_S	0.502	0.34
458_F	462_H	0.502	0.34
350_T	356_G	0.501	0.34
328_N	331_A	0.500	0.34
436_V	495_N	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4l4uA	2	0.6182	100	0.434	Contact Map
1ojlA	3	0.5068	100	0.558	Contact Map
3dzdA	2	0.5929	100	0.567	Contact Map
4fwgA	3	0.6199	100	0.697	Contact Map
4qhsA	3	0.4122	100	0.732	Contact Map
4qosA	1	0.4054	100	0.737	Contact Map
1r6bX	1	0.7635	100	0.754	Contact Map
1qvrA	3	0.8176	100	0.763	Contact Map
4ciuA	1	0.8159	100	0.765	Contact Map
1in4A	1	0.4443	100	0.766	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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