ATOC - ECOLI - GREMLIN Contacts

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ATOC - Acetoacetate metabolism regulatory protein AtoC

UniProt:	Q06065	Sequences: MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLFADIHPDVVLMDIRMPEMDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDYVIKPFDLDELNLIVQRALQLQSMKKEIRHLHQALSTSWQWGHILTNSPAMMDICKDTAKIALSQASVLISGESGTGKELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHEKGAFTGAQTLRQGLFERANEGTLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIKVDIRIIAATNRDLQAMVKEGTFREDLFYRLNVIHLILPPLRDRREDISLLANHFLQKFSSENQRDIIDIDPMAMSLLTAWSWPGNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQPVCNAGEVKTAPVGERNLKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYKLQEYGIDPADV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11668
Length:	461 (438)
Sequences:	10198 (7143)
Seq/√Len:	341.3

ECOLI - ATOC NTRC GLRR ZRAR NORR HYFR RTCR PRPR FHLA DHAR YGEV TYRR
BACSU - YQIR ACOR ROCR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
292_M	297_T	3.927	1.00
218_E	228_L	3.744	1.00
174_E	317_R	3.744	1.00
429_Q	439_M	3.366	1.00
32_H	49_P	3.212	1.00
203_A	255_A	3.096	1.00
232_L	267_E	3.094	1.00
291_A	295_E	2.956	1.00
234_E	268_R	2.736	1.00
265_E	274_T	2.717	1.00
159_T	182_I	2.674	1.00
62_D	65_K	2.550	1.00
266_F	277_V	2.531	1.00
37_G	61_M	2.525	1.00
333_K	366_S	2.493	1.00
265_E	276_K	2.491	1.00
287_R	292_M	2.464	1.00
36_N	39_T	2.445	1.00
419_K	423_M	2.442	1.00
435_R	438_L	2.438	1.00
17_R	35_N	2.434	1.00
207_E	252_V	2.417	1.00
429_Q	436_T	2.413	1.00
233_F	260_I	2.398	1.00
324_S	350_M	2.203	1.00
100_F	119_A	2.202	1.00
242_L	284_A	2.200	1.00
288_D	291_A	2.198	1.00
346_D	382_F	2.195	1.00
421_I	425_V	2.182	1.00
17_R	33_C	2.163	1.00
345_I	369_I	2.159	1.00
35_N	39_T	2.119	1.00
161_K	377_S	2.098	1.00
327_A	345_I	2.078	1.00
267_E	274_T	2.063	1.00
358_W	368_V	2.054	1.00
10_V	40_A	2.037	1.00
6_R	30_E	2.033	1.00
182_I	313_L	2.030	1.00
292_M	295_E	2.028	1.00
8_L	34_A	2.026	1.00
68_K	97_C	2.026	1.00
218_E	271_G	1.931	1.00
238_E	278_D	1.929	1.00
428_Q	439_M	1.927	1.00
262_Q	366_S	1.920	1.00
324_S	354_T	1.908	1.00
248_E	287_R	1.889	1.00
291_A	294_K	1.857	1.00
356_W	359_P	1.819	1.00
261_L	281_I	1.797	1.00
38_R	60_E	1.769	1.00
51_V	116_V	1.766	1.00
233_F	241_L	1.744	1.00
320_R	324_S	1.742	1.00
192_R	278_D	1.728	1.00
172_S	312_I	1.727	1.00
148_N	325_L	1.707	1.00
177_T	313_L	1.688	1.00
218_E	268_R	1.673	1.00
125_M	129_I	1.673	1.00
418_E	450_K	1.659	1.00
328_N	350_M	1.646	1.00
415_K	453_E	1.626	1.00
327_A	369_I	1.626	1.00
320_R	323_I	1.612	1.00
329_H	333_K	1.612	1.00
283_A	306_L	1.602	1.00
147_T	152_M	1.600	1.00
160_A	189_N	1.591	1.00
21_S	33_C	1.590	1.00
320_R	357_S	1.589	1.00
445_R	449_Y	1.580	1.00
344_D	380_I	1.576	1.00
271_G	275_I	1.573	1.00
346_D	349_A	1.571	1.00
41_L	69_E	1.562	1.00
45_A	73_H	1.561	1.00
349_A	353_L	1.557	1.00
149_S	321_E	1.553	1.00
237_N	277_V	1.541	1.00
6_R	32_H	1.538	1.00
44_F	70_M	1.537	1.00
21_S	25_A	1.523	1.00
260_I	266_F	1.517	1.00
425_V	429_Q	1.512	1.00
32_H	43_L	1.510	1.00
348_M	383_S	1.502	1.00
69_E	72_S	1.498	1.00
349_A	383_S	1.470	1.00
211_E	256_K	1.467	1.00
230_Q	234_E	1.459	1.00
54_M	66_A	1.459	1.00
172_S	310_H	1.454	1.00
312_I	318_D	1.452	1.00
326_L	330_F	1.451	1.00
74_E	77_T	1.447	1.00
289_L	298_F	1.442	1.00
350_M	354_T	1.442	1.00
167_A	370_E	1.441	1.00
34_A	43_L	1.438	1.00
247_G	285_T	1.427	1.00
52_V	70_M	1.418	1.00
152_M	156_C	1.416	1.00
352_L	383_S	1.414	1.00
217_H	222_F	1.413	1.00
381_I	386_L	1.411	1.00
162_I	309_I	1.400	1.00
155_I	311_L	1.397	1.00
80_I	115_I	1.395	1.00
337_E	370_E	1.378	1.00
58_M	61_M	1.376	1.00
180_E	259_R	1.371	1.00
356_W	364_E	1.370	1.00
382_F	385_D	1.368	1.00
237_N	278_D	1.365	1.00
156_C	159_T	1.354	1.00
166_Q	337_E	1.354	1.00
54_M	81_L	1.346	1.00
53_L	116_V	1.340	1.00
229_R	272_H	1.330	1.00
266_F	276_K	1.328	1.00
195_G	238_E	1.324	1.00
157_K	160_A	1.322	1.00
93_E	97_C	1.314	1.00
424_E	428_Q	1.311	1.00
27_Q	113_N	1.296	1.00
88_V	92_V	1.296	1.00
425_V	439_M	1.291	1.00
331_L	373_V	1.280	1.00
154_D	157_K	1.279	1.00
423_M	427_E	1.278	1.00
331_L	345_I	1.271	1.00
67_L	79_V	1.268	1.00
69_E	73_H	1.267	1.00
445_R	448_M	1.266	1.00
425_V	440_L	1.262	1.00
443_S	446_A	1.250	1.00
432_N	444_R	1.248	1.00
207_E	250_P	1.247	1.00
349_A	381_I	1.246	1.00
37_G	66_A	1.245	1.00
334_F	373_V	1.241	1.00
335_S	343_I	1.234	1.00
43_L	49_P	1.232	1.00
446_A	450_K	1.232	1.00
345_I	350_M	1.227	1.00
147_T	156_C	1.225	1.00
7_I	29_F	1.224	1.00
435_R	439_M	1.217	1.00
268_R	271_G	1.216	1.00
234_E	275_I	1.216	1.00
343_I	379_P	1.214	1.00
434_T	438_L	1.213	1.00
324_S	327_A	1.209	1.00
159_T	185_A	1.205	1.00
210_L	253_L	1.201	1.00
166_Q	192_R	1.201	1.00
174_E	315_P	1.199	1.00
37_G	58_M	1.193	1.00
264_R	276_K	1.190	1.00
351_S	355_A	1.187	1.00
330_F	334_F	1.182	1.00
23_A	109_L	1.182	1.00
346_D	380_I	1.181	1.00
90_T	102_Y	1.174	1.00
217_H	221_A	1.173	1.00
29_F	117_Q	1.173	1.00
410_L	413_E	1.172	1.00
52_V	77_T	1.172	1.00
167_A	338_N	1.172	1.00
213_E	229_R	1.167	1.00
433_R	448_M	1.166	1.00
146_L	329_H	1.164	1.00
376_N	385_D	1.159	1.00
36_N	60_E	1.157	1.00
413_E	417_V	1.157	1.00
155_I	182_I	1.155	1.00
203_A	248_E	1.155	1.00
159_T	311_L	1.151	1.00
330_F	366_S	1.148	1.00
155_I	313_L	1.145	1.00
67_L	81_L	1.145	1.00
248_E	286_N	1.144	1.00
158_D	375_M	1.142	1.00
212_S	217_H	1.141	1.00
334_F	369_I	1.140	1.00
11_D	17_R	1.138	1.00
184_R	199_K	1.128	1.00
171_I	182_I	1.127	1.00
247_G	289_L	1.127	1.00
145_I	181_L	1.126	1.00
449_Y	453_E	1.125	1.00
432_N	435_R	1.125	1.00
145_I	156_C	1.123	1.00
41_L	61_M	1.123	1.00
201_N	248_E	1.119	1.00
197_F	239_G	1.118	1.00
171_I	282_I	1.118	1.00
294_K	300_E	1.110	1.00
387_P	390_I	1.107	1.00
422_I	447_L	1.107	1.00
56_I	90_T	1.096	1.00
159_T	186_I	1.096	1.00
11_D	58_M	1.096	1.00
210_L	214_L	1.094	1.00
330_F	369_I	1.093	1.00
210_L	249_M	1.093	1.00
409_N	412_E	1.091	1.00
290_Q	294_K	1.091	1.00
321_E	354_T	1.090	1.00
421_I	440_L	1.090	1.00
414_I	417_V	1.089	1.00
37_G	41_L	1.074	1.00
335_S	341_D	1.074	1.00
443_S	449_Y	1.074	1.00
410_L	414_I	1.071	1.00
144_H	188_Y	1.071	1.00
426_L	451_L	1.067	1.00
32_H	47_I	1.067	1.00
57_R	85_Y	1.067	1.00
145_I	182_I	1.066	1.00
6_R	47_I	1.059	1.00
348_M	382_F	1.056	1.00
434_T	444_R	1.056	1.00
234_E	266_F	1.046	1.00
219_K	227_T	1.043	1.00
93_E	96_R	1.036	1.00
64_I	94_A	1.036	1.00
65_K	68_K	1.036	1.00
372_A	376_N	1.034	1.00
34_A	40_A	1.032	1.00
164_L	191_R	1.023	1.00
328_N	332_Q	1.022	1.00
51_V	120_L	1.020	1.00
170_L	283_A	1.019	1.00
240_T	282_I	1.017	1.00
332_Q	336_S	1.017	1.00
54_M	79_V	1.015	1.00
185_A	189_N	1.010	1.00
425_V	436_T	1.008	1.00
417_V	421_I	1.007	1.00
281_I	306_L	1.006	1.00
168_S	264_R	1.004	1.00
6_R	49_P	1.001	1.00
53_L	112_L	1.000	1.00
320_R	354_T	1.000	1.00
125_M	128_E	1.000	1.00
221_A	269_I	0.998	1.00
9_I	31_T	0.993	1.00
323_I	327_A	0.990	1.00
167_A	308_V	0.988	1.00
27_Q	117_Q	0.978	1.00
420_R	424_E	0.978	1.00
436_T	439_M	0.978	1.00
237_N	279_I	0.977	1.00
222_F	225_A	0.976	1.00
54_M	58_M	0.971	1.00
174_E	177_T	0.966	1.00
180_E	199_K	0.965	1.00
217_H	269_I	0.963	1.00
335_S	342_I	0.962	1.00
212_S	222_F	0.956	1.00
307_N	310_H	0.947	1.00
323_I	353_L	0.946	1.00
241_L	281_I	0.939	1.00
423_M	456_I	0.936	1.00
56_I	81_L	0.936	1.00
290_Q	389_Q	0.931	1.00
66_A	70_M	0.929	1.00
152_M	155_I	0.926	1.00
235_R	272_H	0.924	1.00
371_R	375_M	0.923	1.00
70_M	79_V	0.923	1.00
68_K	93_E	0.922	1.00
424_E	427_E	0.919	1.00
147_T	325_L	0.906	1.00
422_I	440_L	0.901	1.00
166_Q	191_R	0.900	1.00
123_Q	127_K	0.892	1.00
147_T	182_I	0.887	1.00
53_L	80_I	0.886	1.00
198_I	235_R	0.885	1.00
409_N	441_G	0.885	1.00
433_R	451_L	0.885	1.00
169_V	186_I	0.885	1.00
426_L	436_T	0.883	1.00
345_I	381_I	0.883	1.00
155_I	159_T	0.883	1.00
366_S	370_E	0.882	1.00
16_V	107_F	0.881	1.00
39_T	42_H	0.878	1.00
233_F	279_I	0.876	1.00
150_P	154_D	0.876	1.00
420_R	423_M	0.875	1.00
241_L	260_I	0.873	1.00
50_D	123_Q	0.872	1.00
168_S	283_A	0.871	1.00
10_V	66_A	0.870	1.00
217_H	229_R	0.868	1.00
36_N	58_M	0.866	1.00
121_Q	124_S	0.866	1.00
415_K	454_Y	0.865	1.00
351_S	354_T	0.864	1.00
172_S	290_Q	0.861	1.00
156_C	182_I	0.859	1.00
199_K	259_R	0.858	1.00
217_H	228_L	0.857	1.00
24_F	116_V	0.857	1.00
308_V	367_N	0.857	1.00
446_A	449_Y	0.857	1.00
184_R	188_Y	0.856	1.00
43_L	47_I	0.855	1.00
345_I	349_A	0.853	1.00
249_M	253_L	0.849	1.00
422_I	450_K	0.844	1.00
42_H	46_D	0.840	1.00
268_R	275_I	0.838	1.00
167_A	374_V	0.835	1.00
14_D	17_R	0.834	1.00
151_A	154_D	0.833	1.00
198_I	236_A	0.833	1.00
266_F	275_I	0.832	1.00
42_H	45_A	0.832	1.00
433_R	445_R	0.830	1.00
11_D	16_V	0.830	1.00
444_R	448_M	0.827	1.00
431_G	451_L	0.826	1.00
217_H	225_A	0.825	1.00
328_N	344_D	0.820	1.00
372_A	381_I	0.819	1.00
147_T	159_T	0.818	1.00
54_M	70_M	0.818	1.00
433_R	440_L	0.816	1.00
387_P	391_R	0.812	1.00
171_I	313_L	0.811	1.00
235_R	271_G	0.811	1.00
39_T	43_L	0.808	1.00
37_G	60_E	0.807	1.00
12_D	55_D	0.804	1.00
114_L	118_R	0.804	1.00
448_M	452_Q	0.803	1.00
96_R	101_D	0.803	1.00
43_L	46_D	0.802	1.00
9_I	20_L	0.801	1.00
443_S	448_M	0.801	1.00
146_L	325_L	0.800	1.00
61_M	65_K	0.800	1.00
121_Q	126_K	0.799	1.00
201_N	249_M	0.798	1.00
171_I	183_A	0.792	1.00
307_N	371_R	0.791	1.00
347_P	350_M	0.791	1.00
148_N	153_M	0.790	1.00
323_I	354_T	0.790	1.00
153_M	156_C	0.789	1.00
153_M	157_K	0.788	1.00
419_K	454_Y	0.786	1.00
340_R	373_V	0.785	1.00
41_L	66_A	0.785	1.00
206_P	269_I	0.785	1.00
145_I	152_M	0.785	1.00
53_L	82_M	0.782	1.00
142_W	185_A	0.782	1.00
51_V	78_P	0.780	1.00
162_I	169_V	0.778	1.00
38_R	42_H	0.778	1.00
230_Q	235_R	0.777	1.00
426_L	433_R	0.774	1.00
65_K	69_E	0.772	1.00
167_A	309_I	0.772	1.00
422_I	451_L	0.772	1.00
44_F	52_V	0.771	1.00
34_A	39_T	0.769	1.00
340_R	343_I	0.769	1.00
290_Q	303_F	0.767	1.00
414_I	421_I	0.765	1.00
7_I	24_F	0.763	1.00
54_M	67_L	0.762	1.00
343_I	373_V	0.762	1.00
230_Q	272_H	0.762	1.00
440_L	450_K	0.761	1.00
205_L	214_L	0.760	1.00
34_A	37_G	0.760	1.00
12_D	105_K	0.757	1.00
293_V	303_F	0.756	1.00
61_M	69_E	0.754	1.00
121_Q	125_M	0.751	1.00
92_V	96_R	0.750	1.00
10_V	52_V	0.748	1.00
233_F	277_V	0.742	0.99
82_M	107_F	0.742	0.99
413_E	416_R	0.739	0.99
327_A	350_M	0.739	0.99
447_L	451_L	0.737	0.99
68_K	72_S	0.737	0.99
228_L	268_R	0.736	0.99
20_L	112_L	0.736	0.99
368_V	372_A	0.735	0.99
228_L	273_Q	0.733	0.99
233_F	266_F	0.733	0.99
433_R	444_R	0.732	0.99
108_D	111_E	0.732	0.99
442_I	446_A	0.731	0.99
163_A	190_S	0.731	0.99
448_M	451_L	0.726	0.99
324_S	328_N	0.725	0.99
228_L	271_G	0.724	0.99
290_Q	300_E	0.723	0.99
150_P	153_M	0.721	0.99
334_F	366_S	0.717	0.99
247_G	286_N	0.713	0.99
115_I	119_A	0.712	0.99
13_E	16_V	0.710	0.99
290_Q	310_H	0.709	0.99
8_L	49_P	0.708	0.99
55_D	105_K	0.708	0.99
63_G	105_K	0.707	0.99
327_A	372_A	0.704	0.99
29_F	113_N	0.700	0.99
23_A	113_N	0.700	0.99
71_R	78_P	0.699	0.99
440_L	446_A	0.699	0.99
232_L	235_R	0.698	0.99
320_R	325_L	0.697	0.99
9_I	21_S	0.695	0.99
229_R	232_L	0.695	0.99
44_F	74_E	0.693	0.99
6_R	50_D	0.692	0.99
142_W	156_C	0.692	0.99
249_M	257_L	0.692	0.99
157_K	377_S	0.691	0.99
413_E	421_I	0.690	0.99
38_R	61_M	0.690	0.99
338_N	373_V	0.690	0.99
155_I	158_D	0.690	0.99
206_P	209_L	0.690	0.99
412_E	416_R	0.686	0.99
429_Q	435_R	0.686	0.99
12_D	83_T	0.685	0.99
450_K	454_Y	0.684	0.99
142_W	189_N	0.683	0.99
86_A	104_I	0.681	0.99
161_K	375_M	0.680	0.99
217_H	226_Q	0.680	0.99
447_L	450_K	0.679	0.99
161_K	385_D	0.678	0.99
334_F	338_N	0.678	0.99
12_D	63_G	0.677	0.99
411_K	425_V	0.676	0.99
259_R	263_E	0.676	0.99
10_V	58_M	0.676	0.99
247_G	298_F	0.673	0.99
89_E	93_E	0.673	0.99
151_A	318_D	0.672	0.99
315_P	318_D	0.670	0.99
12_D	84_A	0.669	0.99
372_A	386_L	0.668	0.99
88_V	91_A	0.668	0.99
67_L	99_A	0.667	0.99
156_C	185_A	0.666	0.99
352_L	356_W	0.664	0.99
427_E	431_G	0.664	0.99
331_L	369_I	0.663	0.99
223_T	284_A	0.659	0.99
347_P	351_S	0.658	0.99
56_I	62_D	0.656	0.99
118_R	125_M	0.656	0.99
444_R	449_Y	0.655	0.99
102_Y	111_E	0.651	0.99
91_A	99_A	0.648	0.99
221_A	225_A	0.648	0.99
442_I	447_L	0.647	0.99
219_K	228_L	0.647	0.99
14_D	18_R	0.646	0.99
20_L	82_M	0.646	0.99
158_D	161_K	0.644	0.99
44_F	77_T	0.643	0.99
148_N	321_E	0.643	0.99
78_P	126_K	0.640	0.99
175_S	248_E	0.639	0.99
302_L	306_L	0.639	0.99
229_R	235_R	0.637	0.98
161_K	340_R	0.636	0.98
128_E	136_L	0.634	0.98
117_Q	121_Q	0.633	0.98
247_G	287_R	0.630	0.98
181_L	185_A	0.630	0.98
246_I	306_L	0.629	0.98
303_F	307_N	0.629	0.98
64_I	93_E	0.628	0.98
107_F	112_L	0.627	0.98
247_G	284_A	0.627	0.98
150_P	321_E	0.626	0.98
101_D	115_I	0.623	0.98
352_L	386_L	0.623	0.98
451_L	456_I	0.623	0.98
415_K	419_K	0.621	0.98
219_K	226_Q	0.620	0.98
410_L	417_V	0.619	0.98
290_Q	293_V	0.619	0.98
44_F	49_P	0.618	0.98
426_L	431_G	0.617	0.98
45_A	69_E	0.617	0.98
52_V	66_A	0.616	0.98
200_V	232_L	0.615	0.98
411_K	450_K	0.614	0.98
327_A	331_L	0.614	0.98
114_L	125_M	0.614	0.98
78_P	122_L	0.613	0.98
432_N	448_M	0.610	0.98
416_R	420_R	0.607	0.98
264_R	279_I	0.606	0.98
100_F	115_I	0.606	0.98
335_S	340_R	0.605	0.98
449_Y	452_Q	0.604	0.98
325_L	328_N	0.604	0.98
219_K	225_A	0.604	0.98
233_F	281_I	0.603	0.98
242_L	282_I	0.603	0.98
8_L	40_A	0.602	0.98
412_E	420_R	0.602	0.98
165_S	374_V	0.602	0.98
152_M	182_I	0.600	0.98
331_L	335_S	0.599	0.98
445_R	452_Q	0.595	0.98
76_R	130_R	0.595	0.98
335_S	373_V	0.594	0.98
223_T	286_N	0.593	0.98
232_L	274_T	0.591	0.98
334_F	370_E	0.590	0.97
86_A	91_A	0.590	0.97
432_N	436_T	0.586	0.97
19_M	23_A	0.586	0.97
200_V	241_L	0.584	0.97
86_A	102_Y	0.582	0.97
36_N	61_M	0.582	0.97
163_A	189_N	0.581	0.97
22_T	26_L	0.581	0.97
220_G	225_A	0.579	0.97
214_L	253_L	0.578	0.97
209_L	223_T	0.578	0.97
352_L	390_I	0.577	0.97
180_E	263_E	0.577	0.97
237_N	264_R	0.577	0.97
218_E	275_I	0.577	0.97
166_Q	338_N	0.575	0.97
200_V	214_L	0.574	0.97
40_A	66_A	0.573	0.97
192_R	195_G	0.572	0.97
109_L	113_N	0.571	0.97
433_R	436_T	0.570	0.97
228_L	275_I	0.569	0.97
145_I	185_A	0.568	0.97
422_I	454_Y	0.568	0.97
103_V	107_F	0.568	0.97
157_K	161_K	0.566	0.97
238_E	279_I	0.565	0.97
25_A	31_T	0.563	0.97
82_M	103_V	0.561	0.97
159_T	189_N	0.560	0.97
373_V	376_N	0.560	0.97
7_I	120_L	0.559	0.97
410_L	440_L	0.559	0.97
55_D	84_A	0.559	0.97
58_M	63_G	0.555	0.96
177_T	181_L	0.554	0.96
111_E	114_L	0.553	0.96
78_P	123_Q	0.552	0.96
287_R	297_T	0.551	0.96
247_G	292_M	0.551	0.96
120_L	123_Q	0.551	0.96
82_M	85_Y	0.551	0.96
129_I	136_L	0.550	0.96
331_L	342_I	0.549	0.96
158_D	309_I	0.548	0.96
444_R	447_L	0.546	0.96
410_L	421_I	0.545	0.96
144_H	185_A	0.544	0.96
154_D	158_D	0.544	0.96
434_T	437_A	0.544	0.96
418_E	422_I	0.544	0.96
147_T	322_D	0.541	0.96
433_R	447_L	0.540	0.96
309_I	374_V	0.540	0.96
230_Q	266_F	0.538	0.96
52_V	79_V	0.538	0.96
244_D	363_R	0.538	0.96
64_I	90_T	0.537	0.96
232_L	272_H	0.535	0.96
386_L	389_Q	0.535	0.96
111_E	115_I	0.534	0.96
212_S	220_G	0.534	0.96
182_I	185_A	0.533	0.95
49_P	77_T	0.533	0.95
342_I	373_V	0.532	0.95
414_I	450_K	0.531	0.95
168_S	308_V	0.530	0.95
192_R	279_I	0.530	0.95
433_R	450_K	0.530	0.95
368_V	390_I	0.530	0.95
209_L	269_I	0.529	0.95
338_N	374_V	0.529	0.95
164_L	190_S	0.529	0.95
70_M	77_T	0.528	0.95
416_R	419_K	0.528	0.95
83_T	105_K	0.528	0.95
17_R	37_G	0.528	0.95
260_I	263_E	0.527	0.95
12_D	58_M	0.527	0.95
104_I	111_E	0.526	0.95
356_W	390_I	0.526	0.95
364_E	389_Q	0.525	0.95
21_S	31_T	0.524	0.95
442_I	450_K	0.524	0.95
329_H	332_Q	0.524	0.95
196_P	235_R	0.522	0.95
155_I	162_I	0.521	0.95
89_E	111_E	0.521	0.95
264_R	277_V	0.521	0.95
15_N	19_M	0.521	0.95
445_R	450_K	0.520	0.95
201_N	255_A	0.519	0.95
57_R	87_E	0.519	0.95
205_L	210_L	0.518	0.95
227_T	272_H	0.517	0.95
309_I	375_M	0.516	0.95
346_D	383_S	0.515	0.95
218_E	221_A	0.514	0.95
170_L	285_T	0.514	0.95
377_S	385_D	0.514	0.95
237_N	276_K	0.513	0.94
230_Q	268_R	0.512	0.94
292_M	298_F	0.512	0.94
433_R	449_Y	0.512	0.94
100_F	122_L	0.512	0.94
213_E	232_L	0.511	0.94
9_I	24_F	0.511	0.94
190_S	280_R	0.510	0.94
260_I	277_V	0.509	0.94
7_I	51_V	0.508	0.94
352_L	387_P	0.507	0.94
352_L	355_A	0.506	0.94
321_E	324_S	0.505	0.94
183_A	197_F	0.504	0.94
237_N	266_F	0.504	0.94
421_I	436_T	0.504	0.94
222_F	229_R	0.503	0.94
421_I	443_S	0.503	0.94
201_N	204_A	0.503	0.94
162_I	311_L	0.502	0.94
308_V	370_E	0.502	0.94
151_A	321_E	0.501	0.94
142_W	160_A	0.501	0.94
337_E	366_S	0.501	0.94
63_G	84_A	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4l4uA	2	0.833	100	0.104	Contact Map
3dzdA	2	0.7983	100	0.278	Contact Map
1ojlA	3	0.6529	100	0.453	Contact Map
4fwgA	3	0.6334	100	0.625	Contact Map
1r6bX	1	0.8482	100	0.647	Contact Map
3pxiA	3	0.7961	100	0.654	Contact Map
1qvrA	3	0.8286	100	0.654	Contact Map
4qosA	1	0.5206	100	0.666	Contact Map
4qhsA	3	0.5293	100	0.666	Contact Map
4d2uA	3	0.8373	100	0.667	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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