FEAB - ECOLI - GREMLIN Contacts

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FEAB - Phenylacetaldehyde dehydrogenase

UniProt:	P80668	Sequences: MTEPHVAVLSQVQQFLDRQHGLYIDGRPGPAQSEKRLAIFDPATGQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEELAQLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIAGKTLDLSIPLPQGARYQAWTRKEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGIPDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLELGGKNPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSLQVGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVNPDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRLQAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCVRY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13179
Length:	499 (455)
Sequences:	36421 (21937)
Seq/√Len:	1028.4

ECOLI - FEAB PUUC GABD ALDB BETB ABDH ALDA ASTD SAD EUTE PUTA PAAZ PROA
BACSU - ALDH4 ROCA ROCA2 ALDH1 ALDH5 IOLA BETB ALDY GABD ALDH3 ALDH2 PROA
HALSA - Q9HQZ2 Q9HMJ6 Q9HRB5 Q9HR91
SULSO - Q97YT9 GAPN KGSDH Q97XS9 Q97XA5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
316_A	415_A	4.994	1.00
260_R	264_D	3.939	1.00
316_A	413_R	3.140	1.00
288_Q	325_G	3.098	1.00
319_F	413_R	2.900	1.00
38_A	50_S	2.823	1.00
376_N	386_A	2.782	1.00
67_W	242_H	2.770	1.00
283_K	315_E	2.713	1.00
394_D	397_L	2.662	1.00
351_R	355_D	2.606	1.00
363_D	398_R	2.574	1.00
292_E	329_A	2.572	1.00
208_R	211_E	2.541	1.00
362_D	366_A	2.530	1.00
323_V	411_L	2.492	1.00
283_K	317_P	2.446	1.00
97_H	100_E	2.394	1.00
95_E	129_R	2.367	1.00
437_T	443_A	2.336	1.00
38_A	47_E	2.334	1.00
67_W	244_A	2.229	1.00
214_S	220_D	2.222	1.00
55_N	58_D	2.201	1.00
361_L	385_V	2.194	1.00
98_S	122_G	2.156	1.00
99_E	117_R	2.154	1.00
358_C	362_D	2.134	1.00
90_F	213_A	2.117	1.00
93_L	215_E	2.102	1.00
428_E	474_Q	2.042	1.00
417_G	442_Q	1.998	1.00
370_E	392_N	1.997	1.00
201_T	350_S	1.987	1.00
239_S	261_T	1.982	1.00
162_E	493_K	1.980	1.00
363_D	367_Q	1.975	1.00
358_C	377_G	1.973	1.00
235_A	239_S	1.964	1.00
327_E	331_K	1.941	1.00
100_E	208_R	1.919	1.00
445_E	449_R	1.915	1.00
279_A	294_L	1.910	1.00
358_C	385_V	1.902	1.00
161_K	487_D	1.897	1.00
321_T	325_G	1.893	1.00
365_Q	371_L	1.888	1.00
348_L	357_V	1.882	1.00
86_I	218_I	1.859	1.00
372_I	391_V	1.856	1.00
257_G	260_R	1.823	1.00
64_M	242_H	1.797	1.00
256_K	474_Q	1.786	1.00
93_L	96_Q	1.766	1.00
60_D	236_A	1.764	1.00
284_D	442_Q	1.761	1.00
97_H	215_E	1.754	1.00
313_Y	423_L	1.752	1.00
93_L	216_A	1.740	1.00
400_T	412_V	1.732	1.00
451_Q	473_K	1.727	1.00
161_K	490_C	1.713	1.00
60_D	64_M	1.687	1.00
47_E	50_S	1.674	1.00
327_E	372_I	1.652	1.00
315_E	414_V	1.652	1.00
395_A	423_L	1.635	1.00
330_V	389_L	1.631	1.00
390_V	399_L	1.625	1.00
104_L	208_R	1.624	1.00
88_L	129_R	1.623	1.00
210_A	225_V	1.623	1.00
419_E	422_Q	1.620	1.00
370_E	391_V	1.618	1.00
93_L	212_L	1.618	1.00
313_Y	420_A	1.609	1.00
417_G	445_E	1.607	1.00
71_V	74_R	1.588	1.00
113_I	117_R	1.584	1.00
415_A	419_E	1.582	1.00
95_E	125_L	1.581	1.00
319_F	323_V	1.574	1.00
324_S	328_Q	1.565	1.00
79_L	82_E	1.564	1.00
294_L	322_L	1.563	1.00
299_F	330_V	1.553	1.00
128_M	185_M	1.551	1.00
398_R	402_E	1.535	1.00
359_S	398_R	1.534	1.00
92_D	96_Q	1.527	1.00
325_G	328_Q	1.526	1.00
229_S	232_V	1.524	1.00
193_S	222_V	1.520	1.00
351_R	383_Y	1.509	1.00
287_P	325_G	1.503	1.00
89_R	92_D	1.496	1.00
320_D	413_R	1.477	1.00
312_I	409_V	1.477	1.00
60_D	240_H	1.475	1.00
291_I	325_G	1.473	1.00
371_L	390_V	1.467	1.00
36_R	50_S	1.467	1.00
82_E	85_R	1.467	1.00
46_Q	381_E	1.447	1.00
282_L	442_Q	1.444	1.00
88_L	136_T	1.437	1.00
98_S	117_R	1.436	1.00
77_G	449_R	1.433	1.00
313_Y	414_V	1.428	1.00
211_E	215_E	1.427	1.00
45_G	381_E	1.422	1.00
293_G	436_W	1.414	1.00
103_Q	107_L	1.414	1.00
78_R	82_E	1.413	1.00
418_E	449_R	1.402	1.00
99_E	103_Q	1.400	1.00
329_A	332_S	1.399	1.00
419_E	423_L	1.396	1.00
433_A	452_A	1.394	1.00
314_I	322_L	1.393	1.00
294_L	312_I	1.390	1.00
321_T	324_S	1.389	1.00
91_A	129_R	1.387	1.00
283_K	442_Q	1.383	1.00
134_L	137_K	1.383	1.00
160_R	448_D	1.372	1.00
128_M	181_M	1.368	1.00
362_D	365_Q	1.366	1.00
40_F	47_E	1.365	1.00
319_F	391_V	1.365	1.00
92_D	129_R	1.362	1.00
334_Q	342_V	1.354	1.00
97_H	208_R	1.344	1.00
259_A	477_T	1.342	1.00
169_G	194_I	1.340	1.00
357_V	406_G	1.339	1.00
103_Q	339_M	1.339	1.00
58_D	61_N	1.333	1.00
360_F	404_V	1.323	1.00
106_T	116_S	1.320	1.00
367_Q	398_R	1.320	1.00
35_K	53_D	1.319	1.00
354_C	358_C	1.319	1.00
245_K	270_T	1.305	1.00
414_V	423_L	1.293	1.00
180_G	196_I	1.290	1.00
41_D	44_T	1.283	1.00
282_L	414_V	1.277	1.00
355_D	359_S	1.276	1.00
416_D	419_E	1.272	1.00
320_D	324_S	1.269	1.00
328_Q	331_K	1.260	1.00
354_C	385_V	1.259	1.00
210_A	223_F	1.256	1.00
282_L	446_Y	1.256	1.00
323_V	327_E	1.255	1.00
354_C	377_G	1.251	1.00
331_K	373_R	1.249	1.00
91_A	95_E	1.227	1.00
280_I	420_A	1.224	1.00
351_R	354_C	1.224	1.00
315_E	416_D	1.223	1.00
336_G	343_A	1.215	1.00
421_L	446_Y	1.213	1.00
318_L	321_T	1.209	1.00
235_A	261_T	1.198	1.00
369_A	390_V	1.196	1.00
334_Q	344_Q	1.195	1.00
315_E	318_L	1.192	1.00
396_K	401_R	1.192	1.00
484_D	487_D	1.189	1.00
239_S	264_D	1.188	1.00
59_V	233_C	1.179	1.00
64_M	68_R	1.178	1.00
53_D	229_S	1.173	1.00
483_P	487_D	1.169	1.00
359_S	363_D	1.168	1.00
158_W	444_L	1.167	1.00
161_K	492_T	1.167	1.00
101_L	208_R	1.166	1.00
213_A	223_F	1.165	1.00
325_G	329_A	1.164	1.00
103_Q	113_I	1.160	1.00
63_V	240_H	1.159	1.00
200_E	229_S	1.156	1.00
326_F	409_V	1.153	1.00
78_R	86_I	1.153	1.00
63_V	242_H	1.147	1.00
63_V	243_V	1.141	1.00
433_A	455_V	1.139	1.00
395_A	426_D	1.139	1.00
322_L	326_F	1.133	1.00
447_S	495_V	1.131	1.00
235_A	257_G	1.126	1.00
141_K	483_P	1.122	1.00
257_G	261_T	1.118	1.00
254_T	257_G	1.115	1.00
106_T	338_G	1.112	1.00
56_E	236_A	1.111	1.00
89_R	93_L	1.110	1.00
328_Q	332_S	1.109	1.00
221_G	224_N	1.108	1.00
323_V	391_V	1.107	1.00
418_E	445_E	1.107	1.00
364_A	390_V	1.104	1.00
443_A	457_V	1.102	1.00
88_L	133_G	1.091	1.00
164_V	245_K	1.090	1.00
184_V	223_F	1.090	1.00
253_A	257_G	1.090	1.00
323_V	372_I	1.086	1.00
207_L	227_T	1.085	1.00
37_L	53_D	1.082	1.00
90_F	212_L	1.082	1.00
41_D	337_P	1.080	1.00
401_R	428_E	1.076	1.00
65_S	224_N	1.075	1.00
401_R	426_D	1.075	1.00
418_E	422_Q	1.075	1.00
279_A	309_S	1.075	1.00
378_P	386_A	1.072	1.00
470_G	479_R	1.072	1.00
484_D	492_T	1.071	1.00
90_F	218_I	1.071	1.00
236_A	240_H	1.068	1.00
280_I	446_Y	1.066	1.00
327_E	373_R	1.066	1.00
479_R	491_E	1.064	1.00
49_A	204_L	1.063	1.00
259_A	269_V	1.061	1.00
200_E	230_G	1.060	1.00
90_F	128_M	1.056	1.00
53_D	232_V	1.053	1.00
169_G	247_S	1.051	1.00
331_K	386_A	1.050	1.00
141_K	484_D	1.049	1.00
367_Q	397_L	1.045	1.00
421_L	449_R	1.043	1.00
184_V	194_I	1.032	1.00
101_L	212_L	1.022	1.00
74_R	78_R	1.019	1.00
333_L	345_I	1.019	1.00
168_A	243_V	1.016	1.00
374_G	388_T	1.014	1.00
70_F	76_A	1.014	1.00
286_D	438_Q	1.010	1.00
43_A	338_G	1.003	1.00
280_I	424_A	1.002	1.00
45_G	383_Y	0.998	1.00
414_V	420_A	0.998	1.00
439_N	442_Q	0.997	1.00
354_C	383_Y	0.996	1.00
175_F	305_V	0.992	1.00
69_A	193_S	0.988	1.00
84_E	136_T	0.984	1.00
256_K	266_L	0.983	1.00
124_T	181_M	0.981	1.00
276_K	310_S	0.977	1.00
33_S	55_N	0.974	1.00
417_G	446_Y	0.974	1.00
168_A	237_L	0.974	1.00
97_H	212_L	0.972	1.00
166_V	193_S	0.969	1.00
96_Q	215_E	0.967	1.00
286_D	289_W	0.966	1.00
374_G	386_A	0.964	1.00
207_L	225_V	0.963	1.00
135_T	189_A	0.961	1.00
97_H	211_E	0.960	1.00
71_V	422_Q	0.959	1.00
211_E	214_S	0.959	1.00
337_P	340_S	0.949	1.00
472_M	491_E	0.948	1.00
393_P	397_L	0.946	1.00
357_V	408_V	0.946	1.00
160_R	495_V	0.946	1.00
289_W	293_G	0.944	1.00
295_M	329_A	0.943	1.00
100_E	103_Q	0.943	1.00
107_L	339_M	0.943	1.00
164_V	268_R	0.942	1.00
102_A	117_R	0.941	1.00
360_F	363_D	0.939	1.00
88_L	132_A	0.938	1.00
259_A	263_A	0.935	1.00
288_Q	321_T	0.934	1.00
434_S	460_H	0.931	1.00
157_A	467_L	0.930	1.00
297_G	309_S	0.929	1.00
363_D	366_A	0.928	1.00
56_E	232_V	0.926	1.00
56_E	60_D	0.921	1.00
67_W	71_V	0.920	1.00
422_Q	426_D	0.914	1.00
278_P	433_A	0.913	1.00
162_E	448_D	0.910	1.00
244_A	451_Q	0.910	1.00
359_S	362_D	0.909	1.00
93_L	97_H	0.905	1.00
167_V	245_K	0.901	1.00
298_S	310_S	0.901	1.00
85_R	89_R	0.898	1.00
320_D	323_V	0.894	1.00
111_K	120_E	0.893	1.00
41_D	107_L	0.891	1.00
84_E	88_L	0.887	1.00
80_P	84_E	0.887	1.00
109_Q	202_T	0.886	1.00
76_A	451_Q	0.881	1.00
124_T	177_L	0.881	1.00
70_F	193_S	0.880	1.00
166_V	243_V	0.879	1.00
365_Q	390_V	0.879	1.00
287_P	291_I	0.878	1.00
360_F	398_R	0.878	1.00
59_V	168_A	0.878	1.00
368_Q	397_L	0.877	1.00
201_T	352_A	0.877	1.00
357_V	404_V	0.873	1.00
279_A	436_W	0.871	1.00
412_V	423_L	0.868	1.00
61_N	65_S	0.868	1.00
259_A	262_A	0.867	1.00
77_G	448_D	0.866	1.00
94_V	124_T	0.865	1.00
40_F	383_Y	0.863	1.00
291_I	329_A	0.863	1.00
291_I	326_F	0.862	1.00
282_L	417_G	0.862	1.00
41_D	46_Q	0.861	1.00
319_F	411_L	0.859	1.00
91_A	132_A	0.859	1.00
444_L	448_D	0.859	1.00
162_E	472_M	0.858	1.00
71_V	451_Q	0.858	1.00
355_D	358_C	0.857	1.00
210_A	214_S	0.855	1.00
74_R	77_G	0.854	1.00
256_K	260_R	0.853	1.00
282_L	437_T	0.851	1.00
467_L	494_S	0.845	1.00
433_A	450_L	0.845	1.00
84_E	132_A	0.845	1.00
43_A	384_Y	0.843	1.00
251_S	254_T	0.836	1.00
183_K	480_D	0.835	1.00
395_A	412_V	0.825	1.00
69_A	222_V	0.825	1.00
268_R	491_E	0.824	1.00
246_I	262_A	0.823	1.00
420_A	423_L	0.821	1.00
421_L	425_N	0.820	1.00
57_A	61_N	0.819	1.00
37_L	229_S	0.819	1.00
435_V	446_Y	0.818	1.00
290_V	294_L	0.818	1.00
190_A	490_C	0.811	1.00
71_V	77_G	0.811	1.00
196_I	206_M	0.809	1.00
164_V	491_E	0.809	1.00
57_A	60_D	0.808	1.00
291_I	322_L	0.807	1.00
440_L	443_A	0.806	1.00
281_V	322_L	0.806	1.00
186_P	485_W	0.805	1.00
414_V	419_E	0.804	1.00
207_L	211_E	0.803	1.00
65_S	221_G	0.801	1.00
246_I	258_I	0.801	1.00
75_W	222_V	0.800	1.00
164_V	192_C	0.799	1.00
61_N	64_M	0.799	1.00
324_S	327_E	0.798	1.00
54_A	58_D	0.796	1.00
187_A	194_I	0.794	1.00
375_S	388_T	0.790	1.00
259_A	266_L	0.788	1.00
369_A	397_L	0.784	1.00
361_L	408_V	0.784	1.00
66_A	224_N	0.784	1.00
88_L	92_D	0.783	1.00
335_V	378_P	0.782	1.00
180_G	184_V	0.779	1.00
255_G	273_L	0.773	1.00
114_A	344_Q	0.772	1.00
48_I	107_L	0.771	1.00
198_P	227_T	0.771	1.00
452_A	455_V	0.767	1.00
109_Q	349_V	0.766	1.00
81_A	136_T	0.766	1.00
357_V	385_V	0.765	1.00
181_M	209_V	0.762	1.00
106_T	113_I	0.760	1.00
234_G	238_T	0.758	1.00
95_E	98_S	0.758	1.00
255_G	271_L	0.757	1.00
326_F	389_L	0.755	1.00
87_L	189_A	0.755	1.00
228_G	233_C	0.754	1.00
277_N	310_S	0.751	1.00
107_L	204_L	0.749	1.00
352_A	355_D	0.746	1.00
256_K	264_D	0.744	1.00
86_I	216_A	0.743	1.00
218_I	222_V	0.743	1.00
315_E	417_G	0.742	1.00
252_T	474_Q	0.742	1.00
102_A	113_I	0.742	1.00
278_P	424_A	0.741	1.00
95_E	122_G	0.738	1.00
54_A	62_A	0.737	1.00
169_G	183_K	0.736	1.00
287_P	318_L	0.736	1.00
262_A	269_V	0.735	1.00
113_I	339_M	0.731	1.00
248_F	254_T	0.730	1.00
333_L	344_Q	0.730	1.00
177_L	205_T	0.729	1.00
94_V	125_L	0.729	1.00
291_I	295_M	0.728	1.00
238_T	258_I	0.728	1.00
319_F	392_N	0.727	1.00
218_I	223_F	0.726	1.00
117_R	341_P	0.725	1.00
360_F	402_E	0.725	1.00
290_V	322_L	0.725	1.00
168_A	246_I	0.724	1.00
391_V	413_R	0.723	1.00
438_Q	441_S	0.722	1.00
102_A	106_T	0.720	1.00
180_G	206_M	0.718	1.00
288_Q	329_A	0.718	1.00
238_T	261_T	0.718	1.00
41_D	339_M	0.716	1.00
340_S	343_A	0.713	1.00
89_R	216_A	0.712	1.00
330_V	373_R	0.708	1.00
71_V	76_A	0.708	1.00
99_E	113_I	0.707	1.00
196_I	223_F	0.704	1.00
168_A	234_G	0.703	1.00
201_T	349_V	0.703	1.00
164_V	244_A	0.702	1.00
157_A	494_S	0.701	1.00
66_A	193_S	0.701	1.00
40_F	45_G	0.700	1.00
327_E	330_V	0.697	1.00
282_L	315_E	0.691	1.00
314_I	318_L	0.691	1.00
232_V	235_A	0.690	1.00
295_M	326_F	0.688	1.00
60_D	242_H	0.683	1.00
171_V	180_G	0.683	1.00
356_K	359_S	0.682	1.00
68_R	71_V	0.680	1.00
75_W	86_I	0.680	1.00
260_R	263_A	0.678	1.00
330_V	333_L	0.676	1.00
104_L	204_L	0.675	1.00
69_A	74_R	0.675	1.00
200_E	356_K	0.675	1.00
312_I	322_L	0.674	1.00
350_S	353_H	0.672	1.00
313_Y	400_T	0.671	1.00
302_Q	345_I	0.670	1.00
100_E	211_E	0.669	1.00
416_D	422_Q	0.669	1.00
192_C	490_C	0.669	1.00
45_G	351_R	0.667	1.00
180_G	209_V	0.667	1.00
261_T	264_D	0.666	1.00
92_D	95_E	0.665	1.00
351_R	377_G	0.664	1.00
35_K	232_V	0.662	1.00
440_L	444_L	0.662	1.00
353_H	356_K	0.661	1.00
105_E	108_E	0.661	1.00
364_A	404_V	0.659	1.00
268_R	488_G	0.659	1.00
361_L	390_V	0.658	1.00
233_C	236_A	0.658	1.00
284_D	437_T	0.658	1.00
354_C	378_P	0.657	1.00
59_V	63_V	0.656	1.00
365_Q	376_N	0.656	1.00
59_V	236_A	0.656	1.00
156_Q	444_L	0.655	1.00
80_P	135_T	0.655	1.00
367_Q	396_K	0.655	1.00
76_A	449_R	0.654	1.00
395_A	400_T	0.654	1.00
281_V	290_V	0.652	1.00
295_M	333_L	0.652	1.00
385_V	388_T	0.651	1.00
138_I	490_C	0.651	1.00
313_Y	395_A	0.651	1.00
393_P	399_L	0.649	1.00
160_R	493_K	0.648	1.00
417_G	421_L	0.648	1.00
91_A	125_L	0.648	1.00
75_W	188_L	0.647	1.00
443_A	447_S	0.647	1.00
287_P	321_T	0.647	1.00
36_R	52_A	0.646	1.00
423_L	426_D	0.646	1.00
213_A	218_I	0.645	1.00
200_E	257_G	0.645	1.00
238_T	246_I	0.644	1.00
447_S	457_V	0.644	1.00
487_D	490_C	0.643	1.00
294_L	326_F	0.642	1.00
76_A	162_E	0.641	1.00
451_Q	472_M	0.640	1.00
487_D	492_T	0.639	1.00
326_F	411_L	0.639	1.00
393_P	400_T	0.637	1.00
289_W	438_Q	0.634	1.00
106_T	339_M	0.632	1.00
352_A	356_K	0.631	1.00
101_L	177_L	0.631	1.00
373_R	389_L	0.629	1.00
335_V	345_I	0.628	1.00
358_C	361_L	0.627	1.00
195_V	224_N	0.625	1.00
360_F	364_A	0.623	1.00
82_E	86_I	0.623	1.00
270_T	488_G	0.623	1.00
98_S	102_A	0.621	1.00
289_W	292_E	0.621	1.00
111_K	175_F	0.620	1.00
52_A	227_T	0.619	1.00
259_A	271_L	0.617	1.00
39_I	49_A	0.617	1.00
437_T	442_Q	0.616	1.00
111_K	115_I	0.616	1.00
65_S	220_D	0.615	1.00
284_D	438_Q	0.615	1.00
76_A	163_P	0.614	1.00
157_A	496_C	0.613	1.00
121_V	125_L	0.612	1.00
348_L	353_H	0.612	1.00
105_E	205_T	0.612	1.00
208_R	212_L	0.609	1.00
337_P	343_A	0.609	1.00
138_I	486_L	0.609	1.00
183_K	247_S	0.608	1.00
39_I	108_E	0.607	1.00
184_V	196_I	0.604	1.00
56_E	239_S	0.603	1.00
177_L	209_V	0.603	1.00
441_S	444_L	0.601	1.00
284_D	439_N	0.599	1.00
64_M	67_W	0.599	1.00
105_E	116_S	0.599	1.00
103_Q	106_T	0.599	1.00
51_T	203_P	0.598	1.00
54_A	226_V	0.597	1.00
421_L	445_E	0.597	1.00
390_V	393_P	0.596	1.00
375_S	386_A	0.596	1.00
80_P	189_A	0.595	1.00
371_L	388_T	0.594	1.00
435_V	443_A	0.593	1.00
228_G	234_G	0.592	1.00
94_V	209_V	0.591	1.00
404_V	408_V	0.591	1.00
167_V	192_C	0.590	1.00
158_W	495_V	0.590	1.00
297_G	460_H	0.589	1.00
279_A	312_I	0.588	1.00
441_S	445_E	0.587	1.00
105_E	120_E	0.586	1.00
62_A	226_V	0.584	1.00
94_V	177_L	0.581	1.00
48_I	204_L	0.580	1.00
335_V	344_Q	0.579	1.00
193_S	224_N	0.578	1.00
91_A	128_M	0.576	1.00
252_T	256_K	0.574	1.00
314_I	411_L	0.574	1.00
279_A	434_S	0.573	1.00
245_K	488_G	0.570	1.00
392_N	413_R	0.570	1.00
56_E	235_A	0.570	1.00
361_L	388_T	0.569	1.00
377_G	386_A	0.569	1.00
235_A	238_T	0.568	1.00
66_A	195_V	0.568	1.00
358_C	365_Q	0.567	1.00
288_Q	328_Q	0.567	1.00
298_S	409_V	0.564	1.00
94_V	128_M	0.564	1.00
130_Y	134_L	0.563	1.00
420_A	424_A	0.563	1.00
395_A	422_Q	0.562	1.00
305_V	308_A	0.562	1.00
33_S	58_D	0.562	1.00
67_W	166_V	0.561	1.00
421_L	450_L	0.560	1.00
133_G	136_T	0.559	1.00
102_A	121_V	0.559	1.00
287_P	322_L	0.557	1.00
435_V	457_V	0.556	1.00
30_P	52_A	0.553	1.00
134_L	483_P	0.553	1.00
68_R	74_R	0.553	1.00
80_P	139_A	0.552	1.00
314_I	319_F	0.552	1.00
190_A	486_L	0.551	1.00
277_N	432_T	0.550	1.00
121_V	177_L	0.550	1.00
209_V	213_A	0.549	1.00
287_P	290_V	0.549	1.00
71_V	449_R	0.548	1.00
283_K	414_V	0.548	1.00
424_A	450_L	0.548	1.00
200_E	253_A	0.547	1.00
455_V	493_K	0.545	1.00
327_E	389_L	0.545	1.00
90_F	93_L	0.543	1.00
417_G	449_R	0.542	1.00
39_I	203_P	0.542	1.00
316_A	319_F	0.542	1.00
167_V	194_I	0.541	1.00
348_L	385_V	0.541	1.00
285_A	290_V	0.540	1.00
230_G	234_G	0.540	1.00
367_Q	394_D	0.539	1.00
169_G	184_V	0.539	1.00
35_K	55_N	0.538	1.00
81_A	85_R	0.536	1.00
86_I	90_F	0.536	1.00
62_A	224_N	0.536	1.00
238_T	265_H	0.536	1.00
66_A	166_V	0.535	1.00
131_T	186_P	0.535	1.00
451_Q	491_E	0.533	1.00
334_Q	340_S	0.533	1.00
101_L	121_V	0.532	1.00
166_V	244_A	0.532	1.00
309_S	434_S	0.531	1.00
299_F	333_L	0.531	1.00
74_R	193_S	0.531	1.00
456_W	459_S	0.530	1.00
269_V	477_T	0.529	1.00
51_T	204_L	0.529	1.00
85_R	88_L	0.529	1.00
120_E	175_F	0.528	1.00
65_S	69_A	0.527	1.00
162_E	451_Q	0.527	1.00
33_S	57_A	0.527	1.00
178_M	182_W	0.527	1.00
253_A	352_A	0.527	1.00
399_L	404_V	0.525	1.00
109_Q	301_N	0.523	1.00
188_L	223_F	0.522	1.00
247_S	489_W	0.521	1.00
312_I	411_L	0.521	1.00
450_L	455_V	0.521	1.00
371_L	375_S	0.520	1.00
123_C	178_M	0.520	1.00
62_A	195_V	0.518	1.00
94_V	101_L	0.516	1.00
372_I	392_N	0.516	1.00
182_W	481_F	0.515	1.00
188_L	218_I	0.514	1.00
291_I	318_L	0.514	1.00
53_D	200_E	0.514	1.00
122_G	125_L	0.513	1.00
98_S	125_L	0.511	1.00
214_S	221_G	0.509	1.00
232_V	236_A	0.509	1.00
168_A	195_V	0.507	1.00
30_P	34_E	0.503	1.00
389_L	409_V	0.502	1.00
446_Y	450_L	0.502	1.00
432_T	456_W	0.501	1.00
155_Y	459_S	0.501	1.00
360_F	399_L	0.501	1.00
65_S	68_R	0.501	1.00
324_S	331_K	0.500	1.00
88_L	91_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4o5hA	4	0.998	100	0.048	Contact Map
4yweA	5	0.9419	100	0.051	Contact Map
4qf6A	4	0.982	100	0.052	Contact Map
4pz2A	4	0.9539	100	0.055	Contact Map
4pxlA	4	0.9599	100	0.056	Contact Map
1a4sA	4	0.9679	100	0.058	Contact Map
4wj9A	4	0.9719	100	0.058	Contact Map
3ek1A	5	0.9679	100	0.058	Contact Map
4lihA	5	0.9679	100	0.059	Contact Map
4qtoA	4	0.9699	100	0.061	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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