GREMLIN Database
YDCT - Uncharacterized ABC transporter ATP-binding protein YdcT
UniProt: P77795 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13763
Length: 337 (266)
Sequences: 22774 (15721)
Seq/√Len: 963.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_N22_G3.9091.00
31_E204_R3.9001.00
18_R21_D3.6591.00
199_L220_R3.5771.00
7_F10_V3.2411.00
180_L186_I3.0611.00
8_D60_A3.0411.00
12_R49_L2.8031.00
11_S58_G2.6971.00
6_E26_A2.6491.00
34_S202_S2.6171.00
10_V56_L2.5261.00
47_L157_L2.5161.00
91_M99_Y2.4321.00
90_H133_S2.4111.00
127_V130_R2.2971.00
47_L191_V2.2881.00
218_S221_D2.2791.00
33_F206_A2.2431.00
217_D221_D2.2181.00
28_K31_E2.2091.00
21_D212_R2.1861.00
12_R57_S2.1061.00
48_R53_F2.0881.00
12_R54_E2.0241.00
221_D225_R1.9721.00
11_S22_G1.9301.00
6_E62_S1.9161.00
13_L18_R1.9101.00
130_R134_Q1.9091.00
92_S95_D1.8911.00
178_K200_S1.8881.00
27_I33_F1.8751.00
34_S198_A1.8731.00
77_D154_R1.8661.00
204_R215_Q1.8451.00
7_F25_I1.8341.00
91_M95_D1.8271.00
9_N24_S1.8271.00
94_L98_A1.7991.00
13_L57_S1.7941.00
25_I206_A1.7791.00
91_M96_N1.7121.00
8_D62_S1.6861.00
11_S18_R1.6231.00
219_P223_Y1.6211.00
79_N148_A1.5591.00
49_L56_L1.5361.00
174_Q200_S1.5171.00
206_A213_I1.4571.00
131_K134_Q1.4531.00
110_Q114_M1.4531.00
190_F202_S1.4511.00
152_E186_I1.4421.00
7_F50_I1.4411.00
202_S205_V1.4361.00
223_Y226_P1.4281.00
204_R216_V1.4141.00
11_S21_D1.4071.00
114_M152_E1.4051.00
48_R54_E1.4041.00
95_D98_A1.3941.00
221_D224_M1.3791.00
51_A157_L1.3641.00
225_R228_T1.3611.00
132_P143_V1.3521.00
233_G237_T1.3201.00
88_F91_M1.3061.00
107_N110_Q1.2991.00
113_A117_E1.2871.00
79_N153_P1.2801.00
122_V146_A1.2731.00
8_D24_S1.2691.00
89_P133_S1.2671.00
232_A236_G1.2641.00
207_V226_P1.2621.00
94_L129_Q1.2621.00
219_P222_L1.2501.00
268_P271_L1.2431.00
272_Q276_T1.2361.00
51_A80_T1.2361.00
31_E203_D1.2291.00
96_N147_R1.2221.00
33_F204_R1.2061.00
53_F82_F1.2041.00
103_V108_K1.2001.00
220_R224_M1.1891.00
20_V23_V1.1881.00
256_F260_P1.1881.00
116_Q126_F1.1851.00
276_T280_V1.1811.00
41_S208_F1.1801.00
276_T279_A1.1761.00
114_M117_E1.1701.00
14_Y19_A1.1651.00
264_R267_T1.1551.00
263_I267_T1.1551.00
207_V222_L1.1461.00
165_L173_M1.1461.00
238_S241_F1.1441.00
250_C254_G1.1441.00
192_T198_A1.1411.00
270_E274_N1.1401.00
81_V148_A1.1321.00
27_I187_T1.1251.00
265_L268_P1.1201.00
231_V235_V1.1131.00
118_A150_V1.1091.00
96_N132_P1.1081.00
264_R268_P1.1041.00
94_L115_A1.1011.00
222_L226_P1.0951.00
243_G246_A1.0851.00
116_Q128_H1.0751.00
120_E125_G1.0741.00
123_A126_F1.0681.00
109_K113_A1.0651.00
220_R223_Y1.0651.00
251_G254_G1.0651.00
155_V187_T1.0551.00
90_H131_K1.0511.00
93_I135_L1.0501.00
49_L61_I1.0451.00
38_P41_S1.0441.00
94_L128_H1.0371.00
20_V49_L1.0291.00
223_Y227_R1.0261.00
10_V49_L1.0261.00
209_N212_R1.0241.00
135_L143_V1.0241.00
118_A146_A1.0101.00
119_L128_H1.0021.00
236_G239_N1.0011.00
278_Q282_Y1.0001.00
196_G200_S1.0001.00
12_R45_T0.9991.00
269_G272_Q0.9971.00
98_A115_A0.9941.00
52_G55_Q0.9931.00
175_L179_K0.9911.00
235_V238_S0.9861.00
279_A283_Q0.9841.00
251_G255_S0.9731.00
63_I76_R0.9701.00
171_E175_L0.9681.00
96_N99_Y0.9681.00
92_S96_N0.9671.00
177_L188_F0.9651.00
33_F189_I0.9541.00
217_D222_L0.9531.00
7_F61_I0.9491.00
175_L178_K0.9431.00
100_G147_R0.9381.00
275_G278_Q0.9371.00
238_S242_D0.9351.00
9_N58_G0.9281.00
56_L61_I0.9271.00
273_A276_T0.9271.00
50_I189_I0.9261.00
117_E121_K0.9261.00
234_F238_S0.9251.00
44_T48_R0.9231.00
224_M228_T0.9151.00
258_L262_H0.9061.00
225_R229_P0.9041.00
116_Q120_E0.9021.00
112_H116_Q0.9021.00
259_R262_H0.9021.00
280_V283_Q0.9011.00
261_E264_R0.8981.00
267_T271_L0.8951.00
266_N270_E0.8921.00
256_F259_R0.8921.00
111_R115_A0.8901.00
29_D154_R0.8891.00
260_P263_I0.8831.00
234_F237_T0.8831.00
104_K108_K0.8821.00
213_I216_V0.8801.00
157_L189_I0.8761.00
170_R194_D0.8761.00
32_F188_F0.8761.00
30_G187_T0.8761.00
254_G257_A0.8741.00
109_K112_H0.8731.00
237_T241_F0.8701.00
239_N243_G0.8621.00
224_M227_R0.8551.00
87_L96_N0.8551.00
96_N100_G0.8551.00
206_A216_V0.8531.00
252_M256_F0.8501.00
97_V100_G0.8501.00
237_T240_V0.8491.00
233_G238_S0.8461.00
22_G212_R0.8341.00
125_G128_H0.8311.00
209_N214_E0.8281.00
254_G258_L0.8261.00
22_G58_G0.8241.00
232_A235_V0.8171.00
260_P264_R0.8141.00
64_F76_R0.8141.00
14_Y45_T0.8111.00
219_P230_F0.8071.00
271_L274_N0.8061.00
249_L252_M0.8061.00
177_L201_M0.8041.00
263_I266_N0.8021.00
35_M46_C0.8011.00
257_A260_P0.7991.00
105_G108_K0.7981.00
174_Q197_E0.7971.00
268_P272_Q0.7941.00
252_M255_S0.7941.00
277_I280_V0.7941.00
110_Q113_A0.7901.00
236_G240_V0.7831.00
190_F201_M0.7751.00
245_M248_K0.7721.00
77_D151_N0.7671.00
275_G279_A0.7641.00
244_L247_E0.7621.00
81_V141_Q0.7621.00
28_K204_R0.7611.00
259_R263_I0.7611.00
278_Q281_Q0.7581.00
97_V150_V0.7581.00
263_I268_P0.7561.00
13_L16_D0.7551.00
49_L54_E0.7541.00
253_T256_F0.7501.00
64_F154_R0.7481.00
255_S259_R0.7481.00
111_R116_Q0.7471.00
270_E273_A0.7411.00
267_T270_E0.7401.00
233_G236_G0.7301.00
235_V239_N0.7301.00
253_T257_A0.7261.00
97_V101_L0.7201.00
274_N278_Q0.7191.00
250_C253_T0.7141.00
93_I96_N0.7131.00
32_F190_F0.7121.00
265_L269_G0.7101.00
240_V244_L0.7081.00
239_N242_D0.7071.00
229_P232_A0.7051.00
180_L188_F0.7041.00
167_L171_E0.7031.00
14_Y54_E0.7021.00
118_A121_K0.7021.00
12_R20_V0.7011.00
52_G63_I0.6991.00
277_I281_Q0.6971.00
78_V155_V0.6971.00
258_L261_E0.6941.00
108_K111_R0.6941.00
257_A270_E0.6901.00
101_L104_K0.6891.00
93_I143_V0.6891.00
227_R232_A0.6841.00
274_N279_A0.6821.00
8_D26_A0.6821.00
128_H131_K0.6821.00
94_L97_V0.6811.00
132_P140_R0.6761.00
245_M249_L0.6731.00
120_E126_F0.6721.00
97_V119_L0.6711.00
249_L253_T0.6711.00
214_E229_P0.6701.00
49_L57_S0.6701.00
279_A282_Y0.6651.00
274_N277_I0.6631.00
272_Q275_G0.6631.00
98_A102_M0.6621.00
21_D211_G0.6621.00
228_T233_G0.6571.00
119_L122_V0.6571.00
255_S258_L0.6571.00
266_N269_G0.6561.00
269_G273_A0.6481.00
96_N101_L0.6471.00
82_F85_Y0.6461.00
229_P233_G0.6401.00
252_M267_T0.6381.00
101_L105_G0.6381.00
5_V63_I0.6381.00
242_D245_M0.6381.00
23_V213_I0.6381.00
238_S245_M0.6371.00
259_R264_R0.6361.00
35_M189_I0.6361.00
98_A112_H0.6331.00
205_V219_P0.6331.00
272_Q279_A0.6321.00
259_R267_T0.6321.00
102_M108_K0.6311.00
153_P180_L0.6311.00
277_I282_Y0.6271.00
212_R216_V0.6271.00
228_T232_A0.6271.00
248_K251_G0.6261.00
269_G274_N0.6241.00
94_L116_Q0.6241.00
199_L218_S0.6231.00
160_E193_H0.6221.00
273_A277_I0.6211.00
206_A215_Q0.6211.00
54_E57_S0.6201.00
25_I46_C0.6201.00
107_N111_R0.6151.00
191_V194_D0.6151.00
29_D64_F0.6151.00
46_C208_F0.6141.00
198_A202_S0.6131.00
92_S131_K0.6101.00
83_Q137_G0.6091.00
241_F244_L0.6091.00
218_S222_L0.6061.00
262_H266_N0.6061.00
11_S20_V0.6041.00
80_T83_Q0.5971.00
230_F234_F0.5931.00
262_H265_L0.5931.00
152_E181_Q0.5931.00
247_E250_C0.5921.00
176_E179_K0.5901.00
261_E265_L0.5871.00
234_F239_N0.5861.00
241_F245_M0.5841.00
7_F46_C0.5821.00
170_R197_E0.5821.00
178_K201_M0.5811.00
108_K112_H0.5771.00
5_V155_V0.5771.00
267_T274_N0.5761.00
47_L51_A0.5761.00
10_V61_I0.5741.00
219_P226_P0.5741.00
103_V107_N0.5731.00
27_I155_V0.5721.00
35_M208_F0.5681.00
274_N281_Q0.5671.00
256_F265_L0.5641.00
244_L248_K0.5621.00
258_L263_I0.5591.00
145_I158_L0.5561.00
89_P140_R0.5561.00
9_N12_R0.5561.00
226_P231_V0.5551.00
102_M105_G0.5541.00
266_N271_L0.5541.00
50_I157_L0.5501.00
269_G276_T0.5481.00
101_L150_V0.5451.00
35_M206_A0.5441.00
20_V46_C0.5421.00
36_L207_V0.5411.00
254_G259_R0.5401.00
12_R56_L0.5391.00
87_L132_P0.5381.00
81_V158_L0.5381.00
107_N112_H0.5371.00
230_F235_V0.5361.00
117_E120_E0.5351.00
208_F213_I0.5341.00
36_L205_V0.5331.00
13_L21_D0.5331.00
253_T264_R0.5331.00
278_Q283_Q0.5321.00
121_K179_K0.5321.00
158_L188_F0.5321.00
95_D99_Y0.5311.00
209_N213_I0.5311.00
251_G256_F0.5301.00
275_G281_Q0.5251.00
243_G247_E0.5251.00
156_L186_I0.5231.00
155_V189_I0.5231.00
15_G18_R0.5221.00
154_R186_I0.5221.00
88_F133_S0.5191.00
247_E251_G0.5191.00
252_M257_A0.5171.00
260_P265_L0.5161.00
34_S205_V0.5151.00
226_P229_P0.5151.00
153_P156_L0.5131.00
122_V172_Q0.5131.00
27_I189_I0.5121.00
23_V206_A0.5061.00
231_V234_F0.5061.00
256_F267_T0.5051.00
127_V135_L0.5031.00
233_G240_V0.5021.00
98_A103_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3tuiC 2 0.9733 100 0.238 Contact Map
4u00A 1 0.7033 100 0.243 Contact Map
2oljA 2 0.7033 100 0.246 Contact Map
4yerA 2 0.819 100 0.247 Contact Map
1v43A 2 0.8042 100 0.248 Contact Map
2it1A 1 0.8427 100 0.248 Contact Map
2yyzA 1 0.9911 100 0.25 Contact Map
1g291 4 0.8427 100 0.25 Contact Map
1b0uA 2 0.7151 100 0.254 Contact Map
3fvqA 2 0.9614 100 0.254 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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