YNFF - ECOLI - GREMLIN Contacts

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YNFF - Probable dimethyl sulfoxide reductase chain YnfF

UniProt:	P77783	Sequences: MKIHTTEALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVRAAEAPVEEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGDDVYGNHQVRACLRGRSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVHVLYGTGVDGGNITNSNVPYRLMNSCGGFLSRYGSYSTAQISAAMSYMFGANDGNSPDDIANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLPIRPGTDGALACAIAWVLITENMVDQPFLDKYCVGYDEKTLPANAPRNAHYKAYILGEGPDGIAKTPEWAAKITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTSRAIAMLSVLTGNVGINGGNSGVREGSWDLGVEWFPMLENPVKTQISVFTWTDAIDHGTEMTATRDGVRGKEKLDVPIKFLWCYASNTLINQHGDINHTHEVLQDDSKCEMIVGIDHFMTASAKYCDILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWMLSEVAKRLGPDVYQTFTEGRSQHEWIKYLHAKTKERNPEMPDYEEMKTTGIFKKKCPEEHYVAFRAFREDPQANPLKTPSGKIEIYSERLAKIADTWELKKDEIIHPLPAYTPGFDGWDDPLRKTYPLQLTGFHYKARTHSSYGNIDVLQQACPQEVWINPIDAQARGIRHGDTVRVFNNNGEMLIAAKVTPRILPGVTAIGQGAWLKADMFGDRVDHGGSINILTSHRPSPLAKGNPSHSNLVQIEKV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13844
Length:	807 (665)
Sequences:	8725 (5404)
Seq/√Len:	209.6

ECOLI - YNFF DMSA YNFE TORA NAPA TORZ FDHF BISC YDEP FDNG FDOG NUOG NARZ NARG
BACSU - NASC YOAE YYAE YJGC FDHL NARG
HALSA - DMSA
SULSO - Q97XX8 Q97ZA1 Q97V13

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
117_Y	132_R	5.892	1.00
727_I	746_A	4.704	1.00
140_D	565_R	4.518	1.00
734_R	805_E	4.220	1.00
553_K	561_E	3.687	1.00
734_R	741_E	3.428	1.00
296_E	361_R	3.385	1.00
288_A	345_A	3.307	1.00
721_D	755_G	3.297	1.00
145_N	148_R	3.286	1.00
343_E	353_A	3.217	1.00
686_L	725_R	3.156	1.00
557_W	561_E	3.128	1.00
544_P	547_S	3.112	1.00
292_V	296_E	2.990	1.00
720_I	754_P	2.940	1.00
500_G	512_C	2.908	1.00
141_T	514_I	2.900	1.00
301_Q	305_D	2.869	1.00
122_V	131_E	2.863	1.00
142_I	514_I	2.848	1.00
139_L	565_R	2.802	1.00
291_W	295_T	2.757	1.00
309_V	638_S	2.742	1.00
134_S	137_E	2.736	1.00
736_F	803_Q	2.719	1.00
148_R	152_D	2.706	1.00
736_F	805_E	2.678	1.00
346_A	353_A	2.640	1.00
733_V	746_A	2.640	1.00
285_L	349_T	2.619	1.00
149_I	157_A	2.618	1.00
717_I	746_A	2.616	1.00
290_A	396_L	2.614	1.00
737_N	802_V	2.592	1.00
117_Y	551_E	2.570	1.00
713_Q	745_A	2.557	1.00
227_F	286_A	2.511	1.00
273_E	358_Q	2.503	1.00
133_I	514_I	2.494	1.00
722_A	748_V	2.487	1.00
120_K	141_T	2.484	1.00
222_K	368_P	2.471	1.00
352_P	355_K	2.445	1.00
255_R	362_E	2.432	1.00
717_I	804_I	2.427	1.00
355_K	358_Q	2.425	1.00
120_K	133_I	2.415	1.00
120_K	514_I	2.385	1.00
139_L	561_E	2.350	1.00
353_A	357_I	2.329	1.00
341_T	344_W	2.304	1.00
290_A	326_Y	2.288	1.00
297_N	301_Q	2.288	1.00
736_F	741_E	2.255	1.00
299_V	304_L	2.252	1.00
146_L	466_F	2.250	1.00
481_D	786_H	2.245	1.00
724_A	754_P	2.229	1.00
725_R	803_Q	2.217	1.00
258_V	271_E	2.215	1.00
729_H	748_V	2.166	1.00
638_S	642_E	2.157	1.00
302_P	306_K	2.142	1.00
141_T	145_N	2.142	1.00
221_T	224_V	2.136	1.00
220_N	403_N	2.095	1.00
149_I	466_F	2.070	1.00
358_Q	362_E	2.065	1.00
727_I	733_V	2.062	1.00
132_R	551_E	2.048	1.00
142_I	499_V	2.026	1.00
715_V	757_T	2.021	1.00
561_E	565_R	2.006	1.00
744_I	759_I	2.004	1.00
715_V	733_V	2.001	1.00
549_K	552_R	1.961	1.00
732_T	743_L	1.960	1.00
133_I	141_T	1.959	1.00
223_L	362_E	1.948	1.00
275_L	359_L	1.929	1.00
465_K	496_E	1.928	1.00
273_E	355_K	1.924	1.00
275_L	351_I	1.912	1.00
734_R	743_L	1.897	1.00
70_R	85_T	1.894	1.00
223_L	257_I	1.872	1.00
729_H	747_K	1.868	1.00
717_I	757_T	1.861	1.00
603_E	607_T	1.857	1.00
715_V	759_I	1.854	1.00
291_W	342_P	1.851	1.00
120_K	131_E	1.848	1.00
715_V	735_V	1.837	1.00
285_L	356_I	1.823	1.00
600_D	603_E	1.820	1.00
686_L	757_T	1.812	1.00
281_T	348_I	1.805	1.00
294_I	330_I	1.791	1.00
292_V	361_R	1.771	1.00
487_E	490_Q	1.757	1.00
505_M	509_A	1.754	1.00
296_E	357_I	1.747	1.00
116_K	550_F	1.734	1.00
561_E	564_K	1.728	1.00
298_M	364_G	1.724	1.00
728_R	731_D	1.721	1.00
328_A	331_L	1.717	1.00
140_D	144_D	1.686	1.00
343_E	357_I	1.684	1.00
363_I	397_T	1.677	1.00
294_I	311_Y	1.673	1.00
720_I	723_Q	1.668	1.00
363_I	369_A	1.667	1.00
346_A	356_I	1.657	1.00
292_V	342_P	1.652	1.00
468_W	501_I	1.652	1.00
525_E	544_P	1.646	1.00
346_A	352_P	1.620	1.00
259_I	285_L	1.617	1.00
292_V	357_I	1.614	1.00
716_W	749_T	1.607	1.00
732_T	745_A	1.594	1.00
497_M	514_I	1.593	1.00
273_E	362_E	1.590	1.00
519_L	554_P	1.589	1.00
757_T	802_V	1.588	1.00
396_L	643_I	1.585	1.00
119_M	515_L	1.580	1.00
147_R	151_K	1.571	1.00
133_I	137_E	1.569	1.00
691_F	758_A	1.567	1.00
248_A	254_A	1.563	1.00
345_A	356_I	1.558	1.00
402_I	405_G	1.552	1.00
68_L	91_Y	1.540	1.00
142_I	516_L	1.539	1.00
72_H	82_E	1.539	1.00
249_R	272_D	1.538	1.00
225_V	259_I	1.538	1.00
298_M	361_R	1.535	1.00
55_V	73_V	1.529	1.00
495_C	498_I	1.528	1.00
293_L	299_V	1.525	1.00
107_R	706_V	1.522	1.00
122_V	129_K	1.522	1.00
361_R	365_S	1.517	1.00
686_L	721_D	1.506	1.00
153_Y	465_K	1.498	1.00
146_L	499_V	1.497	1.00
299_V	311_Y	1.483	1.00
285_L	359_L	1.482	1.00
681_R	738_N	1.479	1.00
304_L	311_Y	1.466	1.00
119_M	132_R	1.465	1.00
294_I	327_K	1.460	1.00
308_C	643_I	1.459	1.00
742_M	759_I	1.445	1.00
469_C	498_I	1.444	1.00
284_A	348_I	1.443	1.00
137_E	141_T	1.441	1.00
543_Q	605_K	1.439	1.00
71_L	78_V	1.429	1.00
486_H	490_Q	1.421	1.00
295_T	357_I	1.420	1.00
327_K	331_L	1.414	1.00
223_L	359_L	1.413	1.00
181_M	186_G	1.408	1.00
160_V	181_M	1.405	1.00
444_G	447_M	1.401	1.00
725_R	804_I	1.396	1.00
225_V	359_L	1.391	1.00
144_D	148_R	1.389	1.00
292_V	298_M	1.389	1.00
295_T	331_L	1.389	1.00
56_W	70_R	1.385	1.00
141_T	497_M	1.384	1.00
581_H	585_K	1.382	1.00
719_P	750_P	1.382	1.00
54_A	70_R	1.380	1.00
118_P	135_W	1.379	1.00
500_G	509_A	1.377	1.00
340_K	348_I	1.368	1.00
147_R	150_L	1.362	1.00
553_K	557_W	1.347	1.00
686_L	803_Q	1.346	1.00
293_L	364_G	1.346	1.00
57_S	71_L	1.344	1.00
302_P	305_D	1.341	1.00
505_M	515_L	1.329	1.00
646_E	650_K	1.328	1.00
258_V	267_A	1.328	1.00
277_I	351_I	1.325	1.00
78_V	109_M	1.323	1.00
309_V	642_E	1.322	1.00
340_K	344_W	1.321	1.00
503_H	520_M	1.321	1.00
261_P	274_W	1.314	1.00
602_E	606_T	1.312	1.00
275_L	355_K	1.296	1.00
310_G	313_E	1.296	1.00
350_S	753_L	1.293	1.00
159_H	464_I	1.292	1.00
294_I	299_V	1.292	1.00
564_K	569_D	1.287	1.00
442_D	446_E	1.278	1.00
263_Y	268_A	1.272	1.00
71_L	81_V	1.265	1.00
150_L	158_V	1.264	1.00
139_L	553_K	1.260	1.00
313_E	328_A	1.260	1.00
715_V	744_I	1.259	1.00
554_P	557_W	1.258	1.00
344_W	347_K	1.256	1.00
247_Q	250_E	1.255	1.00
56_W	84_D	1.252	1.00
143_S	565_R	1.248	1.00
292_V	295_T	1.246	1.00
340_K	345_A	1.246	1.00
289_I	363_I	1.237	1.00
431_Q	435_F	1.236	1.00
137_E	514_I	1.235	1.00
615_P	619_Y	1.229	1.00
273_E	359_L	1.229	1.00
121_R	130_F	1.226	1.00
281_T	349_T	1.225	1.00
582_E	585_K	1.214	1.00
222_K	367_K	1.209	1.00
718_N	754_P	1.207	1.00
501_I	558_M	1.206	1.00
150_L	155_N	1.205	1.00
292_V	356_I	1.201	1.00
54_A	72_H	1.200	1.00
366_A	369_A	1.198	1.00
289_I	360_A	1.198	1.00
377_P	390_I	1.193	1.00
70_R	82_E	1.190	1.00
326_Y	330_I	1.190	1.00
113_D	703_N	1.189	1.00
481_D	484_H	1.184	1.00
298_M	365_S	1.182	1.00
70_R	84_D	1.181	1.00
157_A	465_K	1.171	1.00
636_T	642_E	1.171	1.00
624_A	627_E	1.169	1.00
749_T	752_I	1.169	1.00
557_W	564_K	1.162	1.00
301_Q	327_K	1.162	1.00
247_Q	251_R	1.159	1.00
585_K	588_H	1.157	1.00
759_I	780_I	1.156	1.00
122_V	127_E	1.156	1.00
289_I	359_L	1.153	1.00
286_A	390_I	1.149	1.00
575_T	582_E	1.148	1.00
85_T	90_V	1.141	1.00
293_L	397_T	1.138	1.00
150_L	184_C	1.138	1.00
501_I	518_D	1.133	1.00
225_V	289_I	1.132	1.00
288_A	356_I	1.132	1.00
277_I	281_T	1.132	1.00
289_I	293_L	1.131	1.00
466_F	499_V	1.131	1.00
399_N	405_G	1.129	1.00
716_W	747_K	1.127	1.00
77_T	110_N	1.125	1.00
158_V	466_F	1.125	1.00
735_V	759_I	1.121	1.00
683_T	803_Q	1.120	1.00
257_I	359_L	1.117	1.00
217_D	220_N	1.115	1.00
226_M	229_N	1.115	1.00
222_K	366_A	1.113	1.00
519_L	552_R	1.107	1.00
268_A	751_R	1.107	1.00
363_I	371_I	1.106	1.00
470_Y	559_L	1.099	1.00
149_I	496_E	1.098	1.00
224_V	245_V	1.096	1.00
201_A	791_L	1.091	1.00
541_L	605_K	1.088	1.00
683_T	738_N	1.087	1.00
484_H	487_E	1.086	1.00
426_N	429_K	1.081	1.00
291_W	331_L	1.074	1.00
146_L	566_L	1.074	1.00
339_A	344_W	1.071	1.00
83_S	96_V	1.068	1.00
202_A	387_S	1.067	1.00
223_L	366_A	1.066	1.00
757_T	804_I	1.065	1.00
460_L	484_H	1.065	1.00
688_L	802_V	1.061	1.00
622_F	625_F	1.059	1.00
224_V	254_A	1.052	1.00
223_L	369_A	1.051	1.00
149_I	497_M	1.046	1.00
311_Y	327_K	1.046	1.00
218_I	370_Y	1.045	1.00
304_L	643_I	1.043	1.00
289_I	393_L	1.042	1.00
72_H	80_W	1.041	1.00
116_K	132_R	1.041	1.00
145_N	149_I	1.040	1.00
249_R	270_R	1.038	1.00
109_M	546_T	1.037	1.00
585_K	602_E	1.037	1.00
623_R	627_E	1.031	1.00
154_G	157_A	1.030	1.00
81_V	106_R	1.023	1.00
54_A	82_E	1.016	1.00
443_H	446_E	1.016	1.00
116_K	549_K	1.015	1.00
715_V	804_I	1.015	1.00
351_I	356_I	1.014	1.00
115_L	515_L	1.013	1.00
604_M	609_I	1.012	1.00
346_A	349_T	1.012	1.00
441_I	444_G	1.008	1.00
286_A	389_A	1.007	1.00
131_E	137_E	1.004	1.00
446_E	449_A	1.004	1.00
227_F	259_I	1.003	1.00
142_I	497_M	1.002	1.00
309_V	640_K	1.000	1.00
278_R	753_L	0.999	1.00
516_L	558_M	0.998	1.00
469_C	508_S	0.994	1.00
354_E	357_I	0.993	1.00
135_W	516_L	0.993	1.00
716_W	751_R	0.992	1.00
139_L	557_W	0.989	1.00
684_Y	803_Q	0.989	1.00
259_I	359_L	0.988	1.00
345_A	349_T	0.986	1.00
684_Y	737_N	0.983	1.00
74_K	79_Y	0.982	1.00
342_P	357_I	0.981	1.00
584_I	588_H	0.980	1.00
487_E	494_K	0.980	1.00
130_F	515_L	0.976	1.00
219_A	244_Y	0.975	1.00
444_G	448_T	0.973	1.00
689_T	756_V	0.972	1.00
525_E	541_L	0.969	1.00
392_M	643_I	0.968	1.00
681_R	801_L	0.967	1.00
458_E	463_P	0.966	1.00
68_L	84_D	0.966	1.00
457_K	484_H	0.964	1.00
685_P	803_Q	0.962	1.00
369_A	399_N	0.961	1.00
331_L	339_A	0.961	1.00
259_I	277_I	0.961	1.00
291_W	341_T	0.957	1.00
231_P	245_V	0.957	1.00
483_N	487_E	0.956	1.00
717_I	727_I	0.956	1.00
327_K	330_I	0.953	1.00
53_K	76_D	0.953	1.00
292_V	360_A	0.952	1.00
146_L	468_W	0.951	0.99
525_E	581_H	0.946	0.99
299_V	396_L	0.946	0.99
720_I	750_P	0.945	0.99
522_T	545_A	0.945	0.99
279_P	756_V	0.944	0.99
259_I	275_L	0.942	0.99
311_Y	396_L	0.939	0.99
518_D	558_M	0.939	0.99
76_D	547_S	0.937	0.99
288_A	292_V	0.937	0.99
395_V	641_I	0.935	0.99
206_M	388_R	0.935	0.99
468_W	562_V	0.933	0.99
717_I	722_A	0.933	0.99
422_P	432_I	0.927	0.99
346_A	351_I	0.927	0.99
226_M	256_M	0.927	0.99
718_N	752_I	0.925	0.99
357_I	361_R	0.924	0.99
180_L	566_L	0.924	0.99
686_L	804_I	0.923	0.99
466_F	497_M	0.919	0.99
257_I	362_E	0.916	0.99
459_K	462_V	0.916	0.99
255_R	273_E	0.916	0.99
308_C	395_V	0.914	0.99
312_D	327_K	0.913	0.99
475_L	486_H	0.912	0.99
509_A	515_L	0.912	0.99
351_I	355_K	0.912	0.99
742_M	783_L	0.911	0.99
249_R	256_M	0.908	0.99
255_R	272_D	0.908	0.99
283_G	386_T	0.907	0.99
263_Y	751_R	0.906	0.99
353_A	356_I	0.905	0.99
71_L	522_T	0.905	0.99
158_V	184_C	0.903	0.99
257_I	273_E	0.900	0.99
519_L	548_A	0.899	0.99
441_I	446_E	0.899	0.99
326_Y	396_L	0.898	0.99
467_L	495_C	0.897	0.99
739_N	800_N	0.895	0.99
581_H	601_Y	0.894	0.99
135_W	558_M	0.894	0.99
532_S	538_Y	0.891	0.99
261_P	276_P	0.890	0.99
263_Y	750_P	0.889	0.99
300_D	402_I	0.886	0.99
358_Q	361_R	0.884	0.99
718_N	748_V	0.881	0.99
344_W	348_I	0.880	0.99
142_I	562_V	0.879	0.99
473_N	699_S	0.879	0.99
581_H	605_K	0.878	0.99
91_Y	94_H	0.877	0.99
368_P	402_I	0.876	0.99
444_G	449_A	0.875	0.99
180_L	559_L	0.873	0.99
368_P	405_G	0.868	0.99
735_V	802_V	0.868	0.99
442_D	448_T	0.867	0.99
224_V	248_A	0.861	0.99
285_L	289_I	0.860	0.99
223_L	255_R	0.855	0.99
139_L	562_V	0.854	0.99
621_A	624_A	0.852	0.99
744_I	780_I	0.852	0.99
277_I	285_L	0.850	0.99
246_E	249_R	0.849	0.99
142_I	145_N	0.848	0.99
146_L	184_C	0.848	0.99
119_M	505_M	0.847	0.99
136_D	565_R	0.847	0.99
287_C	340_K	0.844	0.99
610_F	614_C	0.843	0.99
118_P	134_S	0.843	0.99
226_M	266_T	0.842	0.99
460_L	494_K	0.842	0.99
55_V	545_A	0.842	0.99
346_A	354_E	0.839	0.99
539_V	599_P	0.837	0.99
604_M	607_T	0.836	0.99
546_T	549_K	0.836	0.99
460_L	487_E	0.836	0.99
506_T	509_A	0.836	0.99
342_P	345_A	0.835	0.99
601_Y	605_K	0.834	0.99
146_L	150_L	0.833	0.99
71_L	545_A	0.832	0.99
278_R	350_S	0.831	0.99
753_L	756_V	0.831	0.99
292_V	353_A	0.828	0.99
284_A	288_A	0.827	0.99
525_E	580_Q	0.826	0.99
341_T	345_A	0.826	0.99
354_E	358_Q	0.826	0.99
719_P	723_Q	0.826	0.99
276_P	753_L	0.823	0.99
120_K	137_E	0.819	0.98
739_N	784_T	0.818	0.98
295_T	342_P	0.816	0.98
58_S	540_I	0.816	0.98
304_L	396_L	0.816	0.98
65_S	237_S	0.815	0.98
69_L	98_A	0.814	0.98
429_K	432_I	0.814	0.98
361_R	364_G	0.813	0.98
625_F	628_D	0.813	0.98
475_L	482_I	0.810	0.98
163_G	188_L	0.808	0.98
375_W	379_R	0.807	0.98
435_F	438_T	0.805	0.98
355_K	362_E	0.804	0.98
717_I	733_V	0.803	0.98
288_A	347_K	0.800	0.98
59_C	63_C	0.799	0.98
634_L	641_I	0.799	0.98
585_K	589_A	0.797	0.98
483_N	782_I	0.797	0.98
594_R	597_E	0.795	0.98
143_S	147_R	0.794	0.98
288_A	344_W	0.794	0.98
428_V	431_Q	0.793	0.98
145_N	497_M	0.790	0.98
135_W	553_K	0.790	0.98
619_Y	622_F	0.789	0.98
622_F	626_R	0.788	0.98
721_D	754_P	0.787	0.98
59_C	67_C	0.784	0.98
735_V	744_I	0.784	0.98
704_I	707_L	0.783	0.98
637_P	642_E	0.783	0.98
714_E	763_A	0.780	0.98
722_A	727_I	0.780	0.98
288_A	342_P	0.779	0.98
442_D	449_A	0.779	0.98
371_I	394_S	0.779	0.98
432_I	435_F	0.778	0.98
232_A	266_T	0.778	0.98
117_Y	134_S	0.778	0.98
433_S	436_T	0.775	0.98
111_H	504_F	0.775	0.98
469_C	500_G	0.774	0.98
293_L	393_L	0.773	0.98
720_I	724_A	0.770	0.98
263_Y	276_P	0.769	0.98
569_D	572_Q	0.769	0.98
63_C	67_C	0.767	0.98
288_A	341_T	0.767	0.98
222_K	251_R	0.763	0.98
109_M	520_M	0.762	0.98
144_D	147_R	0.761	0.98
556_Y	583_W	0.761	0.98
153_Y	157_A	0.760	0.98
576_E	582_E	0.759	0.98
110_N	549_K	0.759	0.98
202_A	391_A	0.758	0.98
291_W	330_I	0.754	0.97
678_D	681_R	0.754	0.97
173_N	176_V	0.753	0.97
225_V	371_I	0.752	0.97
432_I	436_T	0.750	0.97
326_Y	643_I	0.750	0.97
560_S	564_K	0.749	0.97
73_V	546_T	0.748	0.97
377_P	386_T	0.748	0.97
56_W	90_V	0.747	0.97
681_R	685_P	0.745	0.97
475_L	489_L	0.744	0.97
267_A	274_W	0.744	0.97
525_E	543_Q	0.741	0.97
74_K	77_T	0.740	0.97
133_I	138_A	0.739	0.97
381_S	796_P	0.737	0.97
290_A	330_I	0.736	0.97
796_P	799_S	0.736	0.97
260_D	264_N	0.734	0.97
443_H	447_M	0.734	0.97
141_T	144_D	0.733	0.97
76_D	79_Y	0.731	0.97
116_K	119_M	0.730	0.97
457_K	461_D	0.728	0.97
553_K	558_M	0.727	0.97
739_N	801_L	0.725	0.97
342_P	346_A	0.723	0.97
183_S	186_G	0.722	0.97
681_R	684_Y	0.721	0.97
143_S	566_L	0.721	0.97
597_E	600_D	0.719	0.97
223_L	363_I	0.719	0.97
519_L	524_Q	0.718	0.97
507_A	764_W	0.718	0.97
55_V	71_L	0.718	0.97
125_R	128_G	0.718	0.97
304_L	308_C	0.717	0.97
95_Q	247_Q	0.716	0.96
727_I	748_V	0.715	0.96
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147_R	566_L	0.715	0.96
538_Y	611_K	0.714	0.96
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156_E	186_G	0.711	0.96
717_I	748_V	0.710	0.96
601_Y	604_M	0.709	0.96
441_I	448_T	0.708	0.96
738_N	801_L	0.708	0.96
621_A	625_F	0.708	0.96
217_D	404_G	0.706	0.96
139_L	558_M	0.704	0.96
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290_A	393_L	0.702	0.96
219_A	247_Q	0.701	0.96
360_A	364_G	0.700	0.96
445_T	448_T	0.699	0.96
233_E	265_D	0.699	0.96
59_C	102_G	0.698	0.96
176_V	574_F	0.697	0.96
326_Y	329_Y	0.696	0.96
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473_N	508_S	0.693	0.96
122_V	130_F	0.692	0.96
544_P	548_A	0.691	0.96
139_L	142_I	0.690	0.96
152_D	465_K	0.689	0.96
205_Y	388_R	0.689	0.96
511_Y	515_L	0.687	0.96
184_C	568_P	0.687	0.96
232_A	242_T	0.686	0.96
554_P	580_Q	0.686	0.96
624_A	628_D	0.685	0.95
427_P	431_Q	0.685	0.95
354_E	361_R	0.684	0.95
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520_M	549_K	0.680	0.95
642_E	645_S	0.680	0.95
226_M	231_P	0.680	0.95
581_H	588_H	0.679	0.95
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628_D	631_A	0.667	0.95
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602_E	605_K	0.659	0.94
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742_M	780_I	0.656	0.94
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142_I	468_W	0.655	0.94
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140_D	143_S	0.652	0.94
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489_L	511_Y	0.651	0.94
276_P	279_P	0.651	0.94
53_K	73_V	0.651	0.94
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218_I	372_C	0.649	0.94
283_G	382_N	0.649	0.94
329_Y	339_A	0.648	0.94
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557_W	560_S	0.647	0.94
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163_G	166_V	0.645	0.94
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723_Q	728_R	0.645	0.94
255_R	365_S	0.644	0.94
742_M	782_I	0.643	0.94
179_R	182_N	0.642	0.94
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465_K	495_C	0.641	0.94
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183_S	568_P	0.639	0.94
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255_R	358_Q	0.619	0.92
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263_Y	274_W	0.616	0.92
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284_A	344_W	0.616	0.92
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141_T	466_F	0.615	0.92
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484_H	786_H	0.614	0.92
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149_I	153_Y	0.610	0.92
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162_Y	165_G	0.610	0.92
78_V	106_R	0.610	0.92
230_N	260_D	0.609	0.92
181_M	184_C	0.607	0.92
431_Q	434_V	0.607	0.92
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489_L	498_I	0.607	0.92
586_Y	590_K	0.607	0.92
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619_Y	623_R	0.605	0.92
467_L	498_I	0.605	0.92
360_A	393_L	0.604	0.91
609_I	612_K	0.604	0.91
603_E	610_F	0.604	0.91
469_C	474_T	0.603	0.91
739_N	785_S	0.602	0.91
752_I	758_A	0.601	0.91
775_D	778_G	0.601	0.91
486_H	511_Y	0.600	0.91
649_A	652_A	0.599	0.91
788_P	793_K	0.599	0.91
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688_L	759_I	0.597	0.91
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731_D	746_A	0.596	0.91
288_A	353_A	0.595	0.91
678_D	739_N	0.595	0.91
437_W	445_T	0.595	0.91
684_Y	738_N	0.594	0.91
199_I	387_S	0.594	0.91
438_T	441_I	0.593	0.91
623_R	626_R	0.593	0.91
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678_D	801_L	0.591	0.91
435_F	439_D	0.591	0.91
294_I	396_L	0.591	0.91
73_V	78_V	0.591	0.91
294_I	304_L	0.590	0.91
437_W	441_I	0.589	0.90
428_V	433_S	0.588	0.90
368_P	403_N	0.588	0.90
57_S	542_A	0.588	0.90
130_F	133_I	0.588	0.90
419_E	424_L	0.587	0.90
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218_I	245_V	0.586	0.90
214_S	217_D	0.586	0.90
427_P	432_I	0.586	0.90
149_I	465_K	0.586	0.90
251_R	254_A	0.586	0.90
105_I	521_P	0.585	0.90
67_C	99_C	0.585	0.90
618_H	622_F	0.585	0.90
421_F	424_L	0.585	0.90
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785_S	800_N	0.580	0.90
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439_D	444_G	0.579	0.90
453_G	793_K	0.579	0.90
125_R	513_D	0.578	0.90
356_I	360_A	0.576	0.89
303_F	308_C	0.576	0.89
136_D	140_D	0.575	0.89
160_V	177_P	0.575	0.89
638_S	645_S	0.575	0.89
434_V	440_A	0.575	0.89
419_E	422_P	0.575	0.89
439_D	443_H	0.574	0.89
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468_W	559_L	0.572	0.89
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576_E	581_H	0.571	0.89
441_I	449_A	0.571	0.89
518_D	555_I	0.570	0.89
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429_K	434_V	0.570	0.89
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423_M	429_K	0.569	0.89
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67_C	102_G	0.568	0.89
628_D	633_P	0.568	0.89
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428_V	432_I	0.566	0.89
645_S	652_A	0.566	0.89
705_D	709_Q	0.566	0.89
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267_A	270_R	0.564	0.88
440_A	444_G	0.564	0.88
548_A	552_R	0.563	0.88
138_A	516_L	0.563	0.88
604_M	608_G	0.563	0.88
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685_P	725_R	0.562	0.88
598_M	610_F	0.562	0.88
373_Q	407_S	0.562	0.88
150_L	153_Y	0.561	0.88
162_Y	166_V	0.560	0.88
601_Y	609_I	0.559	0.88
117_Y	133_I	0.559	0.88
91_Y	540_I	0.558	0.88
287_C	329_Y	0.558	0.88
300_D	303_F	0.558	0.88
291_W	339_A	0.557	0.88
299_V	327_K	0.557	0.88
601_Y	607_T	0.556	0.88
456_G	459_K	0.556	0.88
386_T	390_I	0.555	0.88
436_T	439_D	0.555	0.88
138_A	142_I	0.554	0.88
503_H	518_D	0.554	0.88
106_R	110_N	0.554	0.88
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290_A	389_A	0.553	0.87
687_Q	799_S	0.553	0.87
594_R	604_M	0.552	0.87
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599_P	604_M	0.551	0.87
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448_T	452_D	0.550	0.87
303_F	307_Y	0.550	0.87
293_L	298_M	0.549	0.87
424_L	429_K	0.549	0.87
693_Y	711_C	0.549	0.87
418_V	424_L	0.548	0.87
607_T	610_F	0.547	0.87
426_N	430_T	0.547	0.87
427_P	433_S	0.547	0.87
721_D	748_V	0.546	0.87
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718_N	721_D	0.546	0.87
646_E	649_A	0.546	0.87
419_E	423_M	0.545	0.87
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382_N	386_T	0.543	0.87
498_I	508_S	0.543	0.87
119_M	130_F	0.543	0.87
388_R	644_Y	0.543	0.87
213_N	370_Y	0.542	0.86
435_F	441_I	0.542	0.86
128_G	131_E	0.542	0.86
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312_D	328_A	0.541	0.86
719_P	748_V	0.541	0.86
692_H	761_Q	0.540	0.86
231_P	266_T	0.540	0.86
572_Q	575_T	0.540	0.86
258_V	266_T	0.540	0.86
719_P	749_T	0.540	0.86
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155_N	185_G	0.535	0.86
448_T	793_K	0.535	0.86
359_L	362_E	0.535	0.86
434_V	437_W	0.534	0.86
81_V	105_I	0.533	0.86
648_L	651_I	0.533	0.86
564_K	573_T	0.533	0.86
278_R	687_Q	0.532	0.85
597_E	607_T	0.532	0.85
246_E	270_R	0.531	0.85
714_E	760_G	0.531	0.85
367_K	402_I	0.531	0.85
585_K	601_Y	0.531	0.85
384_E	792_A	0.530	0.85
594_R	599_P	0.530	0.85
244_Y	247_Q	0.530	0.85
260_D	267_A	0.530	0.85
148_R	151_K	0.529	0.85
594_R	601_Y	0.529	0.85
73_V	79_Y	0.529	0.85
611_K	614_C	0.529	0.85
718_N	725_R	0.529	0.85
115_L	505_M	0.528	0.85
291_W	344_W	0.528	0.85
702_G	705_D	0.528	0.85
377_P	387_S	0.528	0.85
149_I	158_V	0.527	0.85
510_K	766_K	0.526	0.85
447_M	453_G	0.526	0.85
443_H	449_A	0.525	0.85
225_V	393_L	0.524	0.85
441_I	447_M	0.524	0.85
469_C	489_L	0.523	0.84
197_A	794_G	0.523	0.84
439_D	445_T	0.523	0.84
636_T	640_K	0.522	0.84
243_Y	247_Q	0.522	0.84
261_P	277_I	0.522	0.84
468_W	499_V	0.522	0.84
261_P	689_T	0.521	0.84
436_T	441_I	0.521	0.84
111_H	703_N	0.521	0.84
355_K	359_L	0.520	0.84
426_N	435_F	0.520	0.84
393_L	397_T	0.520	0.84
436_T	440_A	0.519	0.84
621_A	628_D	0.519	0.84
201_A	792_A	0.519	0.84
605_K	609_I	0.519	0.84
499_V	514_I	0.518	0.84
436_T	442_D	0.518	0.84
688_L	735_V	0.518	0.84
196_T	411_E	0.517	0.84
117_Y	550_F	0.517	0.84
142_I	146_L	0.516	0.84
133_I	497_M	0.516	0.84
556_Y	560_S	0.516	0.84
727_I	804_I	0.516	0.84
384_E	789_S	0.516	0.84
154_G	465_K	0.515	0.84
289_I	369_A	0.515	0.84
399_N	402_I	0.514	0.83
82_E	85_T	0.514	0.83
445_T	449_A	0.513	0.83
635_K	639_G	0.513	0.83
84_D	90_V	0.512	0.83
289_I	361_R	0.511	0.83
737_N	800_N	0.511	0.83
248_A	256_M	0.511	0.83
564_K	575_T	0.511	0.83
215_P	218_I	0.510	0.83
248_A	251_R	0.510	0.83
73_V	76_D	0.510	0.83
576_E	580_Q	0.509	0.83
619_Y	625_F	0.509	0.83
425_E	428_V	0.508	0.83
645_S	648_L	0.508	0.83
456_G	488_V	0.507	0.83
256_M	270_R	0.507	0.83
343_E	347_K	0.506	0.83
220_N	368_P	0.506	0.83
597_E	601_Y	0.506	0.83
305_D	312_D	0.506	0.83
287_C	330_I	0.505	0.82
229_N	410_R	0.505	0.82
199_I	373_Q	0.505	0.82
737_N	801_L	0.505	0.82
594_R	600_D	0.505	0.82
84_D	91_Y	0.504	0.82
785_S	796_P	0.504	0.82
713_Q	732_T	0.504	0.82
345_A	348_I	0.504	0.82
457_K	460_L	0.504	0.82
490_Q	511_Y	0.504	0.82
422_P	433_S	0.503	0.82
229_N	372_C	0.503	0.82
169_G	470_Y	0.503	0.82
477_N	699_S	0.503	0.82
196_T	199_I	0.503	0.82
350_S	755_G	0.502	0.82
523_E	552_R	0.502	0.82
193_S	196_T	0.502	0.82
165_G	190_R	0.502	0.82
501_I	555_I	0.502	0.82
375_W	378_Q	0.502	0.82
724_A	755_G	0.501	0.82
368_P	399_N	0.500	0.82
260_D	274_W	0.500	0.82

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1kqfA	3	0.8922	100	0.221	Contact Map
2vpzA	1	0.855	100	0.224	Contact Map
2ivfA	1	0.8947	100	0.238	Contact Map
1q16A	2	0.9554	100	0.255	Contact Map
1h0hA	1	0.8922	100	0.258	Contact Map
2e7zA	1	0.8414	100	0.261	Contact Map
2iv2X	1	0.7968	100	0.279	Contact Map
1tmoA	1	0.8736	100	0.283	Contact Map
3ml1A	1	0.8798	100	0.285	Contact Map
2napA	1	0.834	100	0.286	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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