GREMLIN Database
BAMB - Outer membrane protein assembly factor BamB
UniProt: P77774 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14208
Length: 392 (300)
Sequences: 638 (613)
Seq/√Len: 35.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
323_L339_V6.9221.00
284_G298_L5.4421.00
363_D381_Q4.9481.00
259_F296_I3.7571.00
233_S260_A3.5871.00
210_G214_G3.5111.00
260_A270_L3.1261.00
323_L343_E3.1211.00
209_V219_V3.1191.00
298_L308_L3.0131.00
323_L327_L2.9621.00
302_N306_M2.9171.00
286_V289_F2.8331.00
373_A376_G2.6541.00
284_G300_D2.6391.00
252_V255_N2.6061.00
259_F269_A2.6051.00
123_Y133_A2.5991.00
208_V251_P2.5231.00
297_Y337_L2.5231.00
333_Y338_V2.4821.00
260_A268_T2.3701.00
297_Y332_L2.3681.00
175_N178_D2.3661.00
338_V372_V2.3590.99
323_L349_I2.3460.99
329_S370_E2.3000.99
299_V327_L2.2860.99
305_V327_L2.2630.99
290_I332_L2.2590.99
325_R341_D2.1850.99
85_N88_D2.1660.99
329_S340_G2.1170.99
148_A164_I2.1100.99
267_L298_L2.0350.98
283_L308_L2.0080.98
341_D345_Y1.9930.98
116_T119_G1.9580.98
305_V339_V1.9420.98
220_L223_Q1.9340.98
210_G246_D1.9240.98
284_G302_N1.9000.98
290_I293_G1.8710.97
339_V349_I1.8660.97
300_D304_R1.8500.97
323_L341_D1.8310.97
290_I297_Y1.8270.97
338_V348_W1.8240.97
339_V343_E1.7880.97
372_V379_L1.7840.96
307_A319_Q1.7660.96
209_V217_S1.7530.96
81_V134_L1.7340.96
307_A317_W1.7180.96
123_Y157_V1.6470.94
66_A73_Y1.6440.94
363_D367_F1.6380.94
125_G129_A1.6280.94
269_A327_L1.6160.94
300_D303_D1.5970.93
343_E347_H1.5930.93
168_N172_Q1.5830.93
264_N268_T1.5420.92
204_F208_V1.5050.91
121_H133_A1.5020.91
72_V75_A1.4630.90
67_L81_V1.4610.90
233_S264_N1.4530.90
251_P258_V1.4160.88
159_D163_L1.4100.88
300_D308_L1.3910.88
339_V347_H1.3800.87
117_V157_V1.3560.86
369_T372_V1.3560.86
327_L339_V1.3450.86
362_V381_Q1.3410.86
373_A380_I1.3340.85
333_Y372_V1.3230.85
199_A210_G1.3050.84
296_I338_V1.3030.84
159_D254_V1.2690.82
286_V298_L1.2480.81
135_N138_D1.2440.81
281_R284_G1.2370.81
124_I134_L1.2240.80
264_N305_V1.2080.79
322_L343_E1.2050.79
123_Y214_G1.2040.79
218_A367_F1.2010.79
69_D81_V1.1980.78
332_L372_V1.1960.78
298_L302_N1.1930.78
63_L66_A1.1820.77
118_S155_P1.1760.77
197_E202_T1.1720.77
74_A124_I1.1710.77
323_L348_W1.1680.77
366_G380_I1.1640.76
66_A216_V1.1610.76
331_V338_V1.1610.76
282_E340_G1.1530.76
365_S380_I1.1490.75
288_D299_V1.1420.75
331_V371_P1.1410.75
219_V308_L1.1300.74
208_V258_V1.1220.74
360_Q381_Q1.1160.73
334_N343_E1.1140.73
113_G118_S1.1130.73
163_L172_Q1.1070.73
270_L346_L1.1010.72
68_A74_A1.0750.70
110_L116_T1.0720.70
198_S202_T1.0680.70
298_L306_M1.0660.70
363_D366_G1.0660.70
133_A178_D1.0550.69
374_A379_L1.0480.68
65_P68_A1.0380.68
77_R123_Y1.0280.67
208_V218_A1.0260.67
85_N90_K1.0250.67
150_E171_L1.0180.66
231_R345_Y1.0160.66
199_A288_D1.0120.66
72_V203_A1.0120.66
179_G275_G0.9990.65
258_V296_I0.9920.64
322_L347_H0.9910.64
307_A325_R0.9890.64
261_L286_V0.9870.64
217_S339_V0.9850.63
65_P72_V0.9840.63
117_V123_Y0.9820.63
216_V303_D0.9780.63
74_A271_D0.9770.63
223_Q287_N0.9760.63
165_H197_E0.9760.63
116_T203_A0.9730.63
296_I310_I0.9720.62
258_V275_G0.9700.62
116_T123_Y0.9650.62
198_S214_G0.9600.61
256_G370_E0.9580.61
216_V318_T0.9580.61
164_I200_P0.9570.61
113_G116_T0.9540.61
208_V226_M0.9540.61
73_Y258_V0.9540.61
69_D89_G0.9480.60
197_E200_P0.9360.59
271_D274_S0.9350.59
81_V95_V0.9340.59
322_L381_Q0.9340.59
349_I356_F0.9320.59
332_L337_L0.9310.59
233_S262_A0.9290.59
249_T258_V0.9280.59
179_G224_G0.9200.58
203_A296_I0.9180.58
284_G304_R0.9130.58
208_V283_L0.9110.57
359_Q379_L0.9040.57
377_K381_Q0.9040.57
358_A370_E0.8960.56
209_V267_L0.8930.56
205_G220_L0.8920.56
223_Q375_D0.8890.56
91_E350_N0.8880.55
250_T351_V0.8860.55
122_V148_A0.8780.55
341_D349_I0.8730.54
165_H169_G0.8690.54
284_G308_L0.8690.54
246_D260_A0.8690.54
293_G375_D0.8650.53
98_A131_V0.8600.53
337_L351_V0.8590.53
289_F330_P0.8550.53
248_D261_L0.8540.53
208_V272_L0.8510.52
128_K213_N0.8440.52
83_A95_V0.8380.51
171_L307_A0.8340.51
198_S201_T0.8340.51
132_Y178_D0.8310.51
122_V207_A0.8290.50
117_V280_K0.8280.50
257_V271_D0.8230.50
359_Q362_V0.8220.50
299_V307_A0.8200.50
225_Q351_V0.8160.49
125_G158_S0.8160.49
116_T264_N0.8140.49
297_Y310_I0.8140.49
323_L345_Y0.8130.49
251_P332_L0.8130.49
84_L91_E0.8110.49
253_V259_F0.8100.49
77_R165_H0.8100.49
172_Q181_V0.8060.48
286_V308_L0.8030.48
97_L216_V0.8020.48
129_A136_T0.8010.48
268_T302_N0.8010.48
115_V118_S0.7940.47
259_F314_V0.7910.47
305_V330_P0.7910.47
319_Q337_L0.7890.47
320_S337_L0.7890.47
209_V213_N0.7880.47
350_N380_I0.7870.47
274_S352_E0.7820.46
64_H67_L0.7810.46
81_V225_Q0.7780.46
275_G312_G0.7770.46
306_M315_T0.7750.46
308_L313_G0.7740.46
299_V330_P0.7720.45
85_N142_A0.7660.45
262_A306_M0.7610.45
300_D305_V0.7590.44
342_S350_N0.7580.44
94_S326_L0.7570.44
206_A218_A0.7560.44
254_V290_I0.7530.44
356_F372_V0.7530.44
231_R296_I0.7510.44
94_S288_D0.7490.43
365_S372_V0.7480.43
253_V325_R0.7480.43
113_G117_V0.7450.43
94_S124_I0.7410.43
262_A270_L0.7400.43
88_D99_E0.7400.43
175_N264_N0.7390.43
270_L349_I0.7360.42
276_Q336_N0.7360.42
334_N338_V0.7350.42
114_G117_V0.7340.42
163_L166_T0.7340.42
289_F296_I0.7340.42
79_G337_L0.7330.42
313_G372_V0.7310.42
348_W360_Q0.7310.42
225_Q276_Q0.7270.42
340_G367_F0.7260.42
216_V260_A0.7230.41
72_V159_D0.7230.41
132_Y139_G0.7160.41
81_V173_A0.7130.40
205_G208_V0.7070.40
312_G366_G0.7040.40
256_G294_N0.7030.40
259_F267_L0.7020.40
333_Y339_V0.7010.39
147_V174_L0.6990.39
250_T259_F0.6970.39
99_E197_E0.6970.39
66_A331_V0.6960.39
271_D359_Q0.6950.39
67_L70_N0.6940.39
86_A122_V0.6940.39
327_L349_I0.6930.39
216_V304_R0.6930.39
363_D372_V0.6920.39
260_A264_N0.6920.39
125_G152_L0.6920.39
87_D131_V0.6910.39
159_D164_I0.6890.38
162_V281_R0.6880.38
344_G362_V0.6870.38
378_L381_Q0.6860.38
152_L203_A0.6860.38
139_G255_N0.6860.38
111_L209_V0.6830.38
72_V127_E0.6790.38
162_V207_A0.6740.37
188_D209_V0.6720.37
216_V281_R0.6710.37
156_V201_T0.6700.37
162_V330_P0.6700.37
155_P331_V0.6700.37
354_G375_D0.6690.37
198_S216_V0.6650.37
131_V316_L0.6640.36
224_G275_G0.6630.36
328_T346_L0.6620.36
353_D374_A0.6610.36
133_A142_A0.6610.36
262_A268_T0.6590.36
64_H122_V0.6580.36
368_Q375_D0.6580.36
252_V367_F0.6570.36
233_S246_D0.6570.36
292_D295_R0.6570.36
217_S229_Q0.6560.36
131_V322_L0.6550.36
64_H343_E0.6530.36
378_L382_A0.6500.35
346_L362_V0.6460.35
270_L308_L0.6450.35
166_T204_F0.6430.35
62_N68_A0.6420.35
268_T277_I0.6410.35
122_V157_V0.6410.35
157_V163_L0.6400.35
253_V293_G0.6390.35
295_R341_D0.6360.34
233_S284_G0.6360.34
75_A79_G0.6360.34
220_L356_F0.6350.34
357_V364_S0.6340.34
129_A145_T0.6320.34
73_Y83_A0.6310.34
228_W338_V0.6300.34
164_I174_L0.6290.34
65_P86_A0.6270.34
217_S332_L0.6260.33
224_G346_L0.6240.33
132_Y176_E0.6230.33
356_F375_D0.6230.33
217_S285_S0.6210.33
198_S330_P0.6150.33
129_A289_F0.6110.32
307_A351_V0.6110.32
232_I252_V0.6100.32
113_G278_M0.6090.32
196_G206_A0.6070.32
214_G248_D0.6060.32
276_Q372_V0.6050.32
299_V339_V0.6040.32
346_L370_E0.6030.32
281_R292_D0.6010.32
166_T295_R0.6010.32
190_P305_V0.6000.32
246_D262_A0.5980.31
358_A362_V0.5950.31
116_T153_S0.5940.31
116_T133_A0.5930.31
116_T150_E0.5920.31
290_I294_N0.5920.31
81_V337_L0.5900.31
128_K370_E0.5900.31
121_H161_L0.5900.31
76_D83_A0.5870.31
167_S302_N0.5870.31
112_S117_V0.5840.30
337_L355_R0.5840.30
115_V201_T0.5830.30
257_V339_V0.5830.30
220_L361_K0.5820.30
292_D381_Q0.5820.30
286_V312_G0.5800.30
265_G344_G0.5790.30
356_F363_D0.5760.30
159_D338_V0.5760.30
346_L367_F0.5740.30
373_A377_K0.5730.30
226_M340_G0.5730.30
374_A380_I0.5730.30
337_L344_G0.5710.29
366_G382_A0.5710.29
368_Q371_P0.5700.29
203_A254_V0.5690.29
368_Q381_Q0.5680.29
231_R337_L0.5650.29
293_G332_L0.5630.29
196_G268_T0.5630.29
264_N270_L0.5620.29
134_L278_M0.5620.29
132_Y325_R0.5610.29
188_D211_G0.5600.29
257_V336_N0.5600.29
81_V133_A0.5580.28
88_D131_V0.5580.28
335_G339_V0.5570.28
228_W233_S0.5560.28
198_S203_A0.5560.28
64_H165_H0.5550.28
279_W289_F0.5540.28
208_V347_H0.5540.28
346_L357_V0.5530.28
98_A158_S0.5510.28
265_G380_I0.5510.28
198_S225_Q0.5510.28
132_Y161_L0.5480.28
169_G356_F0.5480.28
92_I114_G0.5470.28
88_D139_G0.5470.28
362_V377_K0.5470.28
125_G229_Q0.5470.28
213_N330_P0.5460.28
81_V171_L0.5460.28
208_V255_N0.5450.28
133_A260_A0.5430.27
108_P379_L0.5430.27
150_E258_V0.5420.27
216_V245_S0.5420.27
354_G357_V0.5400.27
284_G306_M0.5400.27
178_D305_V0.5390.27
116_T217_S0.5370.27
66_A115_V0.5370.27
309_T317_W0.5340.27
204_F212_D0.5330.27
133_A173_A0.5330.27
112_S220_L0.5320.27
249_T291_V0.5310.27
203_A282_E0.5300.27
274_S299_V0.5290.26
132_Y141_V0.5280.26
170_Q176_E0.5260.26
113_G122_V0.5250.26
148_A214_G0.5240.26
250_T270_L0.5240.26
204_F372_V0.5230.26
155_P234_Q0.5230.26
210_G233_S0.5220.26
158_S359_Q0.5220.26
112_S260_A0.5210.26
371_P375_D0.5190.26
160_G297_Y0.5180.26
181_V184_T0.5160.26
78_A83_A0.5160.26
168_N210_G0.5140.25
302_N341_D0.5140.25
216_V222_E0.5130.25
202_T269_A0.5130.25
213_N276_Q0.5100.25
310_I335_G0.5100.25
200_P276_Q0.5080.25
360_Q367_F0.5070.25
71_V288_D0.5070.25
285_S307_A0.5070.25
299_V323_L0.5060.25
211_G214_G0.5060.25
136_T275_G0.5050.25
274_S291_V0.5040.25
135_N201_T0.5030.25
228_W253_V0.5030.25
116_T157_V0.5030.25
347_H363_D0.5020.25
289_F328_T0.5010.25
230_Q270_L0.5010.25
361_K378_L0.5010.25
325_R340_G0.5000.25
93_W201_T0.5000.25
251_P372_V0.5000.25
218_A262_A0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ovrB 1 0.8801 100 0.393 Contact Map
4wjuA 1 0.9056 100 0.399 Contact Map
1vyhC 1 0.7296 100 0.401 Contact Map
4nsxA 1 0.9439 100 0.404 Contact Map
4j87A 1 0.7168 100 0.412 Contact Map
4wjsA 1 0.9362 100 0.415 Contact Map
4bzjA 2 0.7985 100 0.42 Contact Map
3sfzA 1 0.9337 100 0.422 Contact Map
4j73A 1 0.7092 100 0.423 Contact Map
2pm9A 1 0.801 100 0.428 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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