GREMLIN Database
ARNC - Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
UniProt: P77757 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14090
Length: 322 (277)
Sequences: 16801 (13439)
Seq/√Len: 807.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_Q53_N4.8491.00
47_D73_L4.4111.00
168_R172_D4.2151.00
53_N56_H3.2511.00
11_S93_G3.1111.00
11_S42_E3.0241.00
121_Y196_I3.0031.00
58_L71_S2.9111.00
95_L117_A2.8341.00
42_E70_V2.6701.00
9_K94_D2.6281.00
16_V54_S2.6241.00
116_K119_E2.6181.00
55_A73_L2.5941.00
47_D50_S2.5771.00
46_I87_G2.5141.00
55_A59_V2.4561.00
24_P60_E2.4391.00
97_I165_A2.3151.00
24_P57_M2.2771.00
170_I193_R2.2661.00
19_E101_A2.2261.00
116_K196_I2.2111.00
24_P28_R2.1821.00
55_A71_S2.1461.00
95_L165_A2.0931.00
45_L58_L2.0881.00
117_A165_A2.0351.00
80_Q84_I2.0211.00
74_L86_A2.0171.00
9_K40_E2.0051.00
27_I61_A1.9841.00
56_H60_E1.9721.00
28_R61_A1.9671.00
112_R200_V1.9661.00
57_M60_E1.9421.00
10_V114_V1.9251.00
11_S44_L1.9231.00
183_F187_L1.9121.00
122_D167_R1.8801.00
9_K92_T1.8791.00
11_S91_V1.8621.00
18_N51_S1.8521.00
116_K198_I1.8441.00
112_R115_A1.8171.00
95_L114_V1.8001.00
53_N57_M1.7871.00
122_D193_R1.7841.00
173_A193_R1.7841.00
59_V73_L1.7751.00
37_L111_P1.7171.00
173_A191_F1.7151.00
113_L165_A1.7061.00
13_V87_G1.7021.00
97_I110_I1.6791.00
42_E93_G1.6651.00
18_N50_S1.6651.00
129_Q201_H1.5881.00
84_I98_T1.5881.00
117_A167_R1.5751.00
88_F171_V1.5601.00
17_Y77_N1.5451.00
86_A90_H1.5421.00
88_F96_I1.5381.00
28_R32_T1.5031.00
37_L40_E1.4971.00
9_K93_G1.4761.00
13_V46_I1.4721.00
25_E28_R1.4461.00
42_E92_T1.4071.00
72_I90_H1.4051.00
149_Q152_T1.4031.00
108_E112_R1.4011.00
16_V101_A1.3801.00
169_H173_A1.3781.00
29_R105_N1.3691.00
46_I83_A1.3671.00
14_I26_L1.3641.00
134_S137_R1.3611.00
47_D55_A1.3501.00
10_V110_I1.3491.00
123_V195_A1.3451.00
29_R108_E1.3391.00
96_I171_V1.3071.00
20_Q57_M1.2921.00
123_V188_A1.2781.00
27_I45_L1.2611.00
91_V168_R1.2401.00
216_R220_L1.2281.00
127_V199_P1.2181.00
25_E206_E1.2081.00
179_E182_T1.1941.00
31_T66_N1.1921.00
56_H59_V1.1871.00
27_I66_N1.1801.00
105_N109_E1.1791.00
115_A118_D1.1741.00
99_L105_N1.1641.00
128_R162_M1.1531.00
80_Q100_D1.1441.00
48_D77_N1.1281.00
60_E65_E1.1231.00
135_W138_K1.1211.00
48_D79_G1.1121.00
115_A119_E1.1111.00
278_F282_G1.1021.00
70_V90_H1.1021.00
96_I168_R1.0991.00
113_L126_T1.0981.00
16_V45_L1.0971.00
44_L70_V1.0881.00
89_S175_L1.0831.00
146_R150_R1.0801.00
86_A89_S1.0791.00
41_Y68_H1.0761.00
29_R104_Q1.0741.00
146_R149_Q1.0741.00
210_S213_S1.0701.00
25_E29_R1.0641.00
135_W139_T1.0611.00
23_L57_M1.0571.00
105_N202_H1.0571.00
167_R170_I1.0521.00
170_I188_A1.0441.00
16_V19_E1.0391.00
12_V110_I1.0371.00
14_I101_A1.0341.00
116_K124_V1.0281.00
223_D226_T1.0211.00
25_E104_Q1.0121.00
95_L167_R1.0061.00
57_M61_A1.0031.00
12_V97_I0.9971.00
109_E163_L0.9951.00
137_R140_A0.9901.00
169_H172_D0.9841.00
87_G91_V0.9841.00
24_P61_A0.9801.00
216_R219_N0.9751.00
60_E63_Q0.9701.00
126_T163_L0.9691.00
27_I31_T0.9651.00
88_F98_T0.9641.00
173_A176_H0.9461.00
282_G286_I0.9421.00
240_G244_A0.9421.00
217_L220_L0.9401.00
8_K118_D0.9361.00
26_L30_T0.9261.00
44_L91_V0.9161.00
14_I43_I0.9121.00
62_S69_I0.9071.00
72_I86_A0.8991.00
116_K120_G0.8991.00
85_M89_S0.8941.00
159_Y164_R0.8931.00
280_F284_Q0.8921.00
33_A111_P0.8841.00
31_T68_H0.8831.00
149_Q153_G0.8781.00
70_V92_T0.8741.00
143_M146_R0.8711.00
29_R33_A0.8701.00
234_R238_L0.8701.00
244_A247_G0.8661.00
22_S206_E0.8661.00
9_K42_E0.8641.00
276_V280_F0.8571.00
198_I201_H0.8551.00
94_D169_H0.8521.00
32_T107_P0.8521.00
14_I30_T0.8501.00
166_Y188_A0.8471.00
14_I45_L0.8461.00
263_P266_A0.8441.00
18_N52_D0.8421.00
23_L54_S0.8411.00
27_I69_I0.8401.00
205_R208_G0.8351.00
240_G247_G0.8341.00
59_V62_S0.8291.00
28_R65_E0.8221.00
19_E22_S0.8201.00
80_Q161_C0.8191.00
26_L29_R0.8141.00
12_V30_T0.8121.00
166_Y171_V0.8111.00
29_R203_A0.8101.00
268_E271_F0.8031.00
84_I100_D0.8021.00
97_I109_E0.7981.00
237_S240_G0.7971.00
103_L205_R0.7941.00
16_V23_L0.7901.00
109_E112_R0.7871.00
117_A124_V0.7861.00
145_N149_Q0.7861.00
45_L69_I0.7841.00
139_T143_M0.7791.00
17_Y51_S0.7781.00
188_A193_R0.7741.00
11_S168_R0.7741.00
112_R116_K0.7721.00
20_Q52_D0.7721.00
136_F140_A0.7701.00
136_F139_T0.7691.00
220_L223_D0.7681.00
29_R32_T0.7681.00
167_R193_R0.7681.00
137_R141_S0.7671.00
111_P115_A0.7651.00
8_K114_V0.7591.00
58_L62_S0.7581.00
59_V63_Q0.7561.00
138_K142_K0.7561.00
41_Y110_I0.7561.00
91_V96_I0.7531.00
269_G272_M0.7501.00
138_K141_S0.7481.00
127_V197_E0.7481.00
30_T43_I0.7461.00
279_T283_A0.7441.00
247_G251_A0.7421.00
113_L201_H0.7411.00
23_L45_L0.7361.00
14_I99_L0.7341.00
78_Y82_S0.7341.00
273_L276_V0.7331.00
15_P83_A0.7321.00
38_G41_Y0.7301.00
228_L231_T0.7221.00
75_N86_A0.7191.00
22_S26_L0.7181.00
196_I199_P0.7151.00
23_L58_L0.7151.00
241_S244_A0.7151.00
18_N54_S0.7151.00
139_T142_K0.7131.00
247_G279_T0.7121.00
94_D167_R0.7111.00
222_Y226_T0.7111.00
148_I152_T0.7101.00
44_L87_G0.7091.00
282_G285_F0.7071.00
81_H85_M0.7001.00
50_S54_S0.6981.00
263_P268_E0.6961.00
266_A271_F0.6961.00
122_D169_H0.6951.00
31_T61_A0.6941.00
81_H180_R0.6931.00
146_R152_T0.6931.00
270_V274_F0.6911.00
37_L41_Y0.6901.00
88_F91_V0.6831.00
147_L152_T0.6821.00
179_E223_D0.6821.00
144_I149_Q0.6811.00
93_G168_R0.6801.00
221_M224_L0.6801.00
129_Q199_P0.6771.00
174_M188_A0.6771.00
281_I285_F0.6761.00
232_P235_M0.6741.00
42_E91_V0.6721.00
249_S253_L0.6661.00
121_Y194_R0.6641.00
112_R198_I0.6641.00
144_I148_I0.6601.00
43_I69_I0.6591.00
258_R262_G0.6581.00
13_V91_V0.6571.00
124_V198_I0.6551.00
241_S245_I0.6531.00
75_N78_Y0.6511.00
23_L28_R0.6501.00
143_M147_L0.6501.00
79_G102_D0.6501.00
39_K118_D0.6481.00
49_G77_N0.6461.00
116_K121_Y0.6461.00
18_N47_D0.6451.00
17_Y48_D0.6431.00
23_L101_A0.6431.00
216_R223_D0.6431.00
48_D100_D0.6411.00
220_L224_L0.6411.00
62_S71_S0.6401.00
113_L117_A0.6401.00
114_V165_A0.6391.00
272_M276_V0.6381.00
178_H187_L0.6381.00
114_V118_D0.6371.00
144_I147_L0.6361.00
239_L244_A0.6351.00
98_T164_R0.6341.00
256_I260_T0.6311.00
113_L163_L0.6311.00
232_P240_G0.6301.00
19_E54_S0.6291.00
103_L203_A0.6261.00
62_S66_N0.6251.00
24_P65_E0.6241.00
33_A110_I0.6241.00
170_I173_A0.6241.00
122_D194_R0.6211.00
238_L242_I0.6201.00
214_F217_L0.6201.00
140_A144_I0.6201.00
214_F218_I0.6191.00
223_D227_C0.6161.00
279_T282_G0.6151.00
184_I188_A0.6141.00
26_L101_A0.6111.00
11_S92_T0.6111.00
234_R237_S0.6101.00
105_N163_L0.6101.00
284_Q288_M0.6101.00
8_K94_D0.6101.00
125_G128_R0.6091.00
278_F281_I0.6091.00
15_P48_D0.6071.00
94_D168_R0.6061.00
183_F186_I0.6021.00
239_L243_I0.6001.00
248_F255_V0.6001.00
66_N69_I0.5991.00
125_G159_Y0.5991.00
278_F285_F0.5961.00
140_A143_M0.5951.00
44_L90_H0.5891.00
30_T105_N0.5851.00
218_I222_Y0.5841.00
215_M218_I0.5831.00
54_S58_L0.5821.00
219_N222_Y0.5781.00
280_F285_F0.5761.00
48_D102_D0.5751.00
137_R142_K0.5741.00
58_L61_A0.5721.00
109_E113_L0.5711.00
38_G114_V0.5701.00
236_L287_G0.5681.00
17_Y49_G0.5661.00
55_A58_L0.5641.00
224_L227_C0.5631.00
254_L257_L0.5591.00
267_A270_V0.5581.00
15_P101_A0.5561.00
135_W140_A0.5561.00
108_E111_P0.5561.00
30_T99_L0.5561.00
285_F289_G0.5551.00
19_E80_Q0.5551.00
245_I249_S0.5551.00
125_G162_M0.5541.00
253_L257_L0.5541.00
113_L116_K0.5531.00
216_R221_M0.5531.00
20_Q56_H0.5521.00
189_N195_A0.5521.00
283_A287_G0.5501.00
9_K41_Y0.5491.00
270_V273_L0.5481.00
49_G74_L0.5471.00
31_T69_I0.5461.00
215_M219_N0.5431.00
281_I284_Q0.5421.00
252_V256_I0.5401.00
219_N223_D0.5391.00
74_L78_Y0.5361.00
121_Y124_V0.5331.00
54_S101_A0.5321.00
185_P188_A0.5311.00
178_H183_F0.5301.00
251_A275_A0.5301.00
250_I254_L0.5301.00
26_L31_T0.5281.00
80_Q98_T0.5271.00
244_A248_F0.5261.00
111_P114_V0.5261.00
277_L280_F0.5261.00
217_L221_M0.5251.00
257_L261_F0.5241.00
80_Q180_R0.5231.00
17_Y47_D0.5231.00
33_A37_L0.5221.00
128_R158_D0.5211.00
147_L151_T0.5201.00
16_V58_L0.5191.00
22_S101_A0.5191.00
142_K146_R0.5171.00
26_L99_L0.5161.00
85_M178_H0.5161.00
170_I174_M0.5141.00
15_P84_I0.5131.00
237_S241_S0.5131.00
233_L237_S0.5121.00
59_V71_S0.5121.00
23_L61_A0.5101.00
106_P109_E0.5091.00
97_I113_L0.5091.00
145_N148_I0.5081.00
275_A279_T0.5071.00
271_F286_I0.5071.00
29_R103_L0.5061.00
218_I221_M0.5061.00
27_I30_T0.5051.00
103_L162_M0.5041.00
26_L103_L0.5041.00
286_I289_G0.5041.00
48_D74_L0.5031.00
208_G211_K0.5031.00
251_A254_L0.5021.00
19_E100_D0.5011.00
104_Q131_R0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4p02A 1 0.972 100 0.401 Contact Map
2z86A 2 0.7671 100 0.451 Contact Map
3bcvA 2 0.5404 100 0.461 Contact Map
2d7iA 1 0.9689 100 0.462 Contact Map
1qg8A 1 0.6646 100 0.467 Contact Map
3l7iA 4 0.0652 100 0.472 Contact Map
1xhbA 1 0.9379 100 0.476 Contact Map
5ajoA 1 0.941 100 0.482 Contact Map
2bo4A 4 0.9037 100 0.485 Contact Map
3ckjA 2 0.795 100 0.492 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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