GREMLIN Database
YDJF - Uncharacterized HTH-type transcriptional regulator YdjF
UniProt: P77721 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13482
Length: 252 (244)
Sequences: 7645 (5639)
Seq/√Len: 361.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
95_T168_I3.3901.00
86_K89_P3.1651.00
108_L206_L2.9921.00
137_K144_E2.7761.00
169_M200_A2.6521.00
100_D193_K2.4881.00
13_M28_I2.3621.00
209_H232_D2.2781.00
110_K130_V2.2591.00
197_I221_A2.2551.00
204_A228_Y2.1371.00
92_D95_T2.1001.00
162_R195_T2.0801.00
168_I204_A2.0691.00
9_A12_Q2.0501.00
98_A166_V2.0491.00
13_M17_D2.0331.00
197_I203_V1.9981.00
81_Q107_E1.9951.00
85_R111_L1.9861.00
219_Q222_D1.9771.00
235_P240_I1.9701.00
99_A105_V1.9361.00
159_E162_R1.9221.00
168_I202_E1.9191.00
98_A196_M1.8551.00
121_L166_V1.8331.00
107_E110_K1.7881.00
93_N115_R1.7811.00
202_E228_Y1.7581.00
240_I244_K1.7521.00
87_A170_V1.7291.00
222_D225_H1.7181.00
166_V196_M1.7071.00
159_E163_R1.6601.00
87_A206_L1.6291.00
158_K191_E1.5991.00
140_S152_L1.5971.00
195_T198_R1.5931.00
167_D201_T1.5691.00
108_L170_V1.5691.00
141_T160_I1.5671.00
182_A226_I1.5591.00
76_F210_S1.5541.00
128_I140_S1.5471.00
241_A245_D1.5271.00
88_L111_L1.5141.00
162_R198_R1.5141.00
31_V36_I1.5051.00
25_L36_I1.5051.00
182_A205_L1.5031.00
19_K57_V1.5001.00
7_I46_E1.4681.00
10_I25_L1.4601.00
84_A111_L1.4581.00
13_M20_V1.4391.00
141_T152_L1.4371.00
157_T192_I1.4351.00
40_L56_A1.4281.00
17_D24_N1.4251.00
81_Q111_L1.4241.00
8_Q12_Q1.4091.00
90_F230_I1.3991.00
195_T199_Q1.3961.00
9_A13_M1.3941.00
76_F79_E1.3881.00
120_L131_L1.3861.00
90_F204_A1.3811.00
15_A58_L1.3741.00
101_S151_S1.3661.00
145_L152_L1.3631.00
50_T59_N1.3581.00
205_L226_I1.3571.00
209_H234_S1.3501.00
23_S33_E1.3481.00
95_T167_D1.3471.00
93_N116_S1.3371.00
52_T55_G1.3351.00
144_E188_A1.3311.00
236_G239_W1.3311.00
79_E232_D1.3291.00
7_I42_K1.2971.00
77_Y107_E1.2861.00
141_T157_T1.2821.00
93_N117_G1.2821.00
80_K103_S1.2821.00
237_A241_A1.2811.00
120_L136_I1.2691.00
94_K117_G1.2681.00
221_A225_H1.2651.00
11_K48_F1.2631.00
21_T24_N1.2461.00
34_E38_R1.2451.00
176_L212_F1.2451.00
91_I112_L1.2401.00
3_A7_I1.2281.00
9_A28_I1.2201.00
86_K90_F1.2181.00
81_Q110_K1.2121.00
241_A244_K1.2091.00
202_E227_N1.2031.00
119_T139_V1.1961.00
109_L131_L1.1771.00
78_E81_Q1.1741.00
9_A29_F1.1701.00
198_R225_H1.1631.00
177_D180_S1.1631.00
12_Q16_N1.1521.00
14_V49_L1.1521.00
98_A199_Q1.1521.00
173_C207_V1.1511.00
212_F235_P1.1381.00
170_V204_A1.1251.00
158_K192_I1.1231.00
17_D28_I1.1221.00
77_Y81_Q1.1211.00
92_D168_I1.1151.00
41_E45_D1.1091.00
175_G183_L1.1041.00
50_T57_V1.0911.00
11_K14_V1.0891.00
203_V226_I1.0861.00
119_T137_K1.0821.00
156_I160_I1.0821.00
79_E209_H1.0801.00
14_V58_L1.0741.00
204_A230_I1.0621.00
173_C220_L1.0571.00
49_L56_A1.0501.00
22_V40_L1.0331.00
139_V144_E1.0301.00
91_I170_V1.0191.00
88_L108_L1.0161.00
42_K46_E1.0131.00
87_A108_L0.9961.00
121_L164_Y0.9941.00
3_A42_K0.9931.00
90_F228_Y0.9921.00
26_S33_E0.9861.00
88_L91_I0.9841.00
212_F229_I0.9821.00
109_L130_V0.9801.00
141_T161_I0.9761.00
79_E83_I0.9751.00
99_A108_L0.9751.00
5_D9_A0.9691.00
174_K184_D0.9631.00
156_I164_Y0.9611.00
239_W242_F0.9571.00
69_F103_S0.9521.00
176_L207_V0.9491.00
80_K104_T0.9441.00
84_A88_L0.9431.00
105_V127_A0.9371.00
169_M196_M0.9361.00
104_T208_D0.9351.00
13_M16_N0.9321.00
224_S246_N0.9241.00
41_E44_E0.9241.00
24_N28_I0.9221.00
80_K211_K0.9191.00
108_L111_L0.9181.00
190_A218_V0.9181.00
102_S105_V0.9171.00
81_Q85_R0.9171.00
165_H201_T0.9111.00
158_K195_T0.9111.00
173_C205_L0.9071.00
191_E194_K0.9061.00
163_R194_K0.9041.00
177_D215_K0.9021.00
26_S36_I0.9021.00
105_V108_L0.8951.00
83_I104_T0.8921.00
126_E150_L0.8901.00
42_K45_D0.8871.00
104_T211_K0.8821.00
84_A107_E0.8791.00
138_V145_L0.8711.00
84_A108_L0.8681.00
165_H180_S0.8651.00
43_L48_F0.8651.00
76_F208_D0.8611.00
109_L127_A0.8541.00
20_V56_A0.8501.00
20_V25_L0.8491.00
164_Y187_E0.8401.00
113_Q130_V0.8381.00
156_I163_R0.8351.00
124_S127_A0.8301.00
165_H219_Q0.8271.00
149_T174_K0.8271.00
184_D190_A0.8231.00
132_A150_L0.8191.00
201_T215_K0.8181.00
11_K15_A0.8171.00
5_D8_Q0.8161.00
170_V206_L0.8161.00
161_I196_M0.8151.00
242_F245_D0.8101.00
12_Q15_A0.8021.00
165_H215_K0.8021.00
87_A230_I0.7981.00
203_V227_N0.7971.00
113_Q133_Q0.7911.00
72_R174_K0.7891.00
98_A161_I0.7781.00
76_F209_H0.7751.00
82_L85_R0.7681.00
41_E51_R0.7671.00
180_S215_K0.7661.00
187_E218_V0.7651.00
176_L182_A0.7641.00
24_N27_G0.7611.00
5_D19_K0.7611.00
105_V206_L0.7611.00
117_G135_E0.7591.00
183_L215_K0.7581.00
99_A120_L0.7561.00
161_I195_T0.7551.00
146_N189_E0.7531.00
165_H199_Q0.7441.00
99_A109_L0.7381.00
106_M130_V0.7331.00
173_C182_A0.7321.00
163_R219_Q0.7321.00
103_S211_K0.7281.00
107_E111_L0.7210.99
235_P239_W0.7180.99
142_G157_T0.7180.99
128_I152_L0.7160.99
129_H150_L0.7130.99
66_N72_R0.7110.99
184_D189_E0.7110.99
78_E82_L0.7110.99
68_H71_K0.6980.99
18_K58_L0.6980.99
197_I220_L0.6980.99
169_M203_V0.6970.99
101_S149_T0.6960.99
166_V200_A0.6940.99
7_I11_K0.6940.99
128_I145_L0.6930.99
184_D220_L0.6920.99
146_N153_Q0.6900.99
208_D211_K0.6870.99
31_V34_E0.6860.99
154_G157_T0.6800.99
182_A220_L0.6750.99
142_G160_I0.6750.99
11_K43_L0.6740.99
123_N196_M0.6740.99
237_A240_I0.6730.99
176_L223_F0.6720.99
207_V229_I0.6710.99
82_L86_K0.6690.99
85_R89_P0.6610.99
52_T57_V0.6610.99
44_E51_R0.6590.99
23_S27_G0.6580.99
40_L51_R0.6560.99
96_T121_L0.6560.99
25_L40_L0.6520.99
171_M200_A0.6510.99
125_A152_L0.6510.99
204_A227_N0.6480.99
22_V36_I0.6470.99
73_A106_M0.6440.99
194_K198_R0.6440.99
34_E124_S0.6400.99
159_E191_E0.6390.99
83_I206_L0.6380.99
155_R159_E0.6380.99
97_M120_L0.6380.99
97_M168_I0.6290.99
162_R199_Q0.6280.99
122_T128_I0.6280.99
238_E242_F0.6260.99
14_V20_V0.6250.99
174_K216_A0.6230.99
106_M126_E0.6200.98
155_R191_E0.6190.98
242_F246_N0.6160.98
44_E49_L0.6140.98
200_A203_V0.6130.98
164_Y218_V0.6110.98
29_F36_I0.6110.98
121_L217_F0.6100.98
117_G137_K0.6060.98
221_A226_I0.6060.98
79_E234_S0.6050.98
133_Q136_I0.6020.98
125_A140_S0.6020.98
4_K7_I0.6010.98
6_R39_D0.6000.98
102_S172_S0.5990.98
174_K189_E0.5900.98
185_S216_A0.5860.98
88_L115_R0.5840.98
72_R189_E0.5830.98
100_D105_V0.5820.98
146_N186_N0.5800.98
73_A107_E0.5800.98
124_S189_E0.5790.98
190_A220_L0.5790.98
171_M220_L0.5770.98
125_A129_H0.5760.98
70_Y73_A0.5760.98
212_F239_W0.5740.98
155_R158_K0.5740.98
91_I108_L0.5710.97
239_W243_C0.5710.97
151_S189_E0.5630.97
234_S240_I0.5630.97
157_T160_I0.5620.97
80_K208_D0.5620.97
97_M170_V0.5610.97
121_L139_V0.5610.97
82_L233_K0.5580.97
96_T217_F0.5550.97
158_K162_R0.5550.97
102_S174_K0.5540.97
174_K185_S0.5540.97
126_E129_H0.5530.97
66_N146_N0.5520.97
34_E174_K0.5520.97
188_A191_E0.5520.97
193_K220_L0.5490.97
172_S184_D0.5490.97
114_D133_Q0.5480.97
177_D183_L0.5440.97
184_D193_K0.5430.97
192_I195_T0.5390.96
131_L136_I0.5360.96
203_V225_H0.5360.96
116_S135_E0.5340.96
209_H235_P0.5320.96
212_F231_T0.5310.96
174_K193_K0.5290.96
102_S124_S0.5280.96
38_R176_L0.5270.96
98_A169_M0.5260.96
171_M197_I0.5230.96
97_M108_L0.5220.96
175_G214_R0.5220.96
98_A121_L0.5220.96
101_S189_E0.5200.96
178_I242_F0.5170.95
171_M203_V0.5130.95
182_A221_A0.5120.95
178_I239_W0.5120.95
99_A127_A0.5110.95
79_E82_L0.5110.95
159_E194_K0.5070.95
152_L160_I0.5060.95
114_D135_E0.5060.95
10_I29_F0.5060.95
237_A244_K0.5040.95
175_G216_A0.5040.95
155_R188_A0.5030.95
149_T184_D0.5030.95
156_I159_E0.5030.95
20_V52_T0.5020.95
137_K147_K0.5010.95
29_F35_T0.5000.95
27_G30_Q0.5000.95
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1stzA 3 0.9405 100 0.512 Contact Map
3rrlB 1 0.6627 100 0.535 Contact Map
2w48A 3 0.9286 100 0.57 Contact Map
3l7oA 2 0.5952 100 0.6 Contact Map
1o8bA 2 0.5833 100 0.603 Contact Map
1m0sA 2 0.6071 100 0.611 Contact Map
1uj6A 2 0.6032 100 0.613 Contact Map
1lk5A 4 0.6032 100 0.613 Contact Map
4io1A 2 0.6071 100 0.616 Contact Map
3uw1A 2 0.6151 100 0.617 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0092 seconds.