YAGH - ECOLI - GREMLIN Contacts

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YAGH - Putative beta-xylosidase

UniProt:	P77713	Sequences: MEITNPILTGFNPDPSLCRQGEDYYIATSTFEWFPGVRIYHSRDLKNWSLVSTPLDRVSMLDMKGNPDSGGIWAPCLSYADGKFWLLYTDVKIVDSPWKNGRNFLVTAPSIEGPWSEPIPMGNGGFDPSLFHDDDGRKYYIYRPWGPRHHSNPHNTIVLQAFDPQTGTLSPERKTLFTGTPLCYTEGAHLYRHAGWYYLMAAEGGTSYEHAVVVLRSKNIDGPYELHPDVTMMTSWHLPENPLQKSGHGSLLQTHTGEWYMAYLTSRPLRLPGVPLLASGGRGYCPLGRETGIARIEWRDGWPYVEGGKHAQLTVKGPQVAEQPAAVPGNWRDDFDASSLDPELQTLRIPFDDTLGSLTARPGFLRLYGNDSLNSTFTQSTVARRWQHFAFRAETRMEFSPVHFQQSAGLTCYYNSKNWSYCFVDYEEGQGRTIKVIQLDHNVPSWPLHEQPIPVPEHAESVWLRVDVDTLVYRYSYSFDGETWHTVPVTYEAWKLSDDYIGGRGFFTGAFVGLHCEDISGDGCYADFDYFTYEPV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13347
Length:	536 (477)
Sequences:	2795 (2127)
Seq/√Len:	97.4

ECOLI - YAGH
BACSU - XYNB XYND EABN2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
23_D	41_H	7.357	1.00
137_R	161_A	6.354	1.00
83_K	109_P	5.402	1.00
196_W	218_K	5.316	1.00
44_D	47_N	5.301	1.00
366_R	527_D	4.570	1.00
108_A	114_P	4.561	1.00
134_D	192_R	4.556	1.00
254_T	258_E	4.084	1.00
22_E	43_R	3.971	1.00
463_W	478_S	3.471	1.00
54_P	86_L	3.215	1.00
23_D	43_R	3.068	1.00
83_K	107_T	2.947	1.00
361_R	364_F	2.895	1.00
396_R	461_S	2.812	1.00
37_V	86_L	2.718	1.00
251_L	296_I	2.704	1.00
7_I	262_A	2.662	1.00
77_L	86_L	2.609	1.00
159_L	221_D	2.552	1.00
200_M	214_V	2.487	1.00
57_R	60_M	2.481	1.00
220_I	224_Y	2.467	1.00
194_A	301_G	2.463	1.00
24_Y	254_T	2.384	1.00
392_R	465_R	2.374	1.00
216_R	302_W	2.359	1.00
392_R	467_D	2.357	1.00
174_K	221_D	2.348	1.00
59_S	117_E	2.337	1.00
476_S	486_T	2.293	1.00
332_R	532_T	2.205	1.00
408_A	526_A	2.197	1.00
261_M	305_V	2.148	1.00
200_M	212_V	2.118	1.00
196_W	216_R	2.112	1.00
357_S	360_A	2.112	1.00
394_E	530_Y	2.087	1.00
393_A	531_F	2.062	1.00
366_R	525_Y	2.054	1.00
361_R	398_E	2.039	1.00
263_Y	294_A	2.038	1.00
72_I	88_Y	2.033	1.00
161_A	170_S	2.029	1.00
345_Q	511_F	2.027	1.00
163_D	166_T	2.020	1.00
163_D	168_T	2.003	1.00
478_S	481_G	2.001	1.00
163_D	167_G	1.988	1.00
219_N	224_Y	1.976	1.00
253_Q	257_G	1.976	1.00
12_N	40_Y	1.966	1.00
159_L	176_L	1.960	1.00
467_D	476_S	1.959	1.00
398_E	461_S	1.944	1.00
192_R	195_G	1.936	1.00
37_V	88_Y	1.926	1.00
253_Q	259_W	1.919	1.00
333_D	344_L	1.892	1.00
212_V	249_G	1.892	1.00
396_R	463_W	1.890	1.00
396_R	530_Y	1.888	1.00
396_R	529_D	1.875	1.00
357_S	361_R	1.846	1.00
478_S	484_W	1.829	1.00
361_R	527_D	1.810	1.00
465_R	484_W	1.806	1.00
260_Y	295_R	1.796	1.00
81_D	136_G	1.789	1.00
162_F	167_G	1.788	1.00
185_T	201_A	1.776	1.00
258_E	295_R	1.769	1.00
411_T	513_G	1.768	1.00
41_H	49_S	1.747	1.00
193_H	301_G	1.742	1.00
141_I	159_L	1.737	1.00
135_D	192_R	1.703	1.00
427_E	430_Q	1.668	1.00
480_D	483_T	1.661	1.00
27_A	77_L	1.653	1.00
177_F	226_L	1.649	1.00
422_C	487_V	1.635	1.00
336_D	529_D	1.620	1.00
86_L	106_V	1.619	1.00
245_K	266_S	1.605	1.00
393_A	410_L	1.603	1.00
22_E	255_H	1.602	1.00
160_Q	169_L	1.599	1.00
214_V	232_M	1.597	1.00
474_R	486_T	1.594	1.00
159_L	220_I	1.584	1.00
412_C	466_V	1.583	1.00
105_L	167_G	1.575	1.00
108_A	112_E	1.575	1.00
390_A	469_D	1.572	1.00
478_S	483_T	1.565	1.00
131_F	190_L	1.563	1.00
28_T	187_G	1.554	1.00
19_R	22_E	1.552	1.00
110_S	114_P	1.543	1.00
465_R	476_S	1.530	1.00
395_T	530_Y	1.507	1.00
364_F	527_D	1.501	1.00
217_S	224_Y	1.486	1.00
407_S	515_H	1.468	1.00
397_M	424_V	1.464	1.00
108_A	113_G	1.455	1.00
55_L	72_I	1.432	1.00
357_S	362_P	1.424	1.00
472_V	490_T	1.424	1.00
159_L	224_Y	1.424	1.00
139_Y	221_D	1.422	1.00
3_I	260_Y	1.419	1.00
175_T	178_T	1.414	1.00
404_F	430_Q	1.406	0.99
334_D	532_T	1.402	0.99
391_F	468_V	1.396	0.99
87_L	140_Y	1.389	0.99
50_L	53_T	1.388	0.99
53_T	345_Q	1.386	0.99
20_Q	84_F	1.376	0.99
27_A	54_P	1.370	0.99
514_L	528_F	1.363	0.99
38_R	53_T	1.363	0.99
30_T	38_R	1.358	0.99
142_Y	160_Q	1.352	0.99
249_G	261_M	1.345	0.99
191_Y	200_M	1.344	0.99
37_V	72_I	1.343	0.99
121_M	140_Y	1.340	0.99
265_T	292_G	1.338	0.99
19_R	255_H	1.338	0.99
216_R	225_E	1.327	0.99
177_F	215_L	1.318	0.99
361_R	366_R	1.311	0.99
19_R	253_Q	1.309	0.99
463_W	480_D	1.309	0.99
266_S	285_C	1.298	0.99
20_Q	79_Y	1.297	0.99
20_Q	23_D	1.293	0.99
214_V	303_P	1.289	0.99
198_Y	214_V	1.272	0.99
17_L	262_A	1.270	0.99
394_E	463_W	1.269	0.99
27_A	75_P	1.268	0.99
37_V	106_V	1.250	0.99
395_T	528_F	1.232	0.99
196_W	217_S	1.227	0.99
358_L	362_P	1.225	0.99
321_A	324_P	1.219	0.99
246_S	265_T	1.215	0.99
133_D	192_R	1.211	0.98
334_D	529_D	1.206	0.98
52_S	114_P	1.202	0.98
478_S	482_E	1.191	0.98
410_L	466_V	1.185	0.98
364_F	529_D	1.183	0.98
27_A	86_L	1.178	0.98
463_W	484_W	1.178	0.98
24_Y	255_H	1.176	0.98
225_E	302_W	1.175	0.98
191_Y	251_L	1.163	0.98
250_S	262_A	1.160	0.98
399_F	406_Q	1.160	0.98
212_V	261_M	1.157	0.98
40_Y	50_L	1.156	0.98
404_F	429_G	1.156	0.98
193_H	298_W	1.153	0.98
57_R	117_E	1.151	0.98
132_H	138_K	1.150	0.98
320_V	323_Q	1.150	0.98
131_F	197_Y	1.150	0.98
193_H	253_Q	1.141	0.98
28_T	40_Y	1.141	0.98
67_P	70_G	1.139	0.98
320_V	324_P	1.136	0.98
37_V	75_P	1.130	0.98
394_E	465_R	1.128	0.98
393_A	512_V	1.125	0.98
333_D	341_D	1.125	0.98
360_A	368_Y	1.122	0.97
41_H	51_V	1.120	0.97
360_A	364_F	1.120	0.97
133_D	136_G	1.120	0.97
216_R	298_W	1.116	0.97
357_S	366_R	1.111	0.97
60_M	106_V	1.107	0.97
218_K	225_E	1.101	0.97
89_T	128_P	1.099	0.97
133_D	197_Y	1.099	0.97
412_C	473_Y	1.096	0.97
243_L	292_G	1.096	0.97
192_R	197_Y	1.094	0.97
459_A	479_F	1.093	0.97
3_I	46_K	1.093	0.97
294_A	305_V	1.092	0.97
234_T	237_H	1.089	0.97
144_P	158_V	1.082	0.97
343_E	384_R	1.077	0.97
51_V	112_E	1.076	0.97
73_W	91_V	1.074	0.97
78_S	132_H	1.064	0.97
37_V	54_P	1.063	0.97
394_E	484_W	1.063	0.97
467_D	474_R	1.059	0.96
9_T	388_H	1.059	0.96
254_T	260_Y	1.053	0.96
466_V	475_Y	1.053	0.96
391_F	512_V	1.051	0.96
190_L	224_Y	1.043	0.96
341_D	344_L	1.032	0.96
161_A	171_P	1.030	0.96
12_N	28_T	1.025	0.96
394_E	532_T	1.023	0.96
333_D	343_E	1.019	0.96
298_W	303_P	1.019	0.96
141_I	190_L	1.015	0.95
357_S	364_F	1.008	0.95
232_M	305_V	1.005	0.95
408_A	528_F	1.004	0.95
157_I	201_A	1.000	0.95
383_A	511_F	0.994	0.95
55_L	106_V	0.991	0.95
320_V	326_A	0.991	0.95
296_I	303_P	0.990	0.95
191_Y	250_S	0.990	0.95
27_A	37_V	0.985	0.95
70_G	92_K	0.977	0.94
474_R	490_T	0.975	0.94
140_Y	187_G	0.971	0.94
182_L	211_A	0.970	0.94
87_L	166_T	0.970	0.94
25_Y	112_E	0.968	0.94
42_S	45_L	0.966	0.94
203_E	213_V	0.962	0.94
41_H	112_E	0.962	0.94
439_L	442_N	0.956	0.94
193_H	259_W	0.954	0.94
320_V	325_A	0.954	0.94
131_F	135_D	0.952	0.94
210_H	247_G	0.947	0.93
107_T	116_S	0.947	0.93
196_W	302_W	0.947	0.93
54_P	106_V	0.946	0.93
44_D	48_W	0.945	0.93
138_K	164_P	0.941	0.93
18_C	84_F	0.941	0.93
108_A	111_I	0.939	0.93
358_L	363_G	0.937	0.93
326_A	329_G	0.934	0.93
352_D	356_G	0.934	0.93
211_A	236_W	0.930	0.93
369_G	518_D	0.930	0.93
217_S	221_D	0.929	0.93
373_L	411_T	0.928	0.93
63_M	66_N	0.928	0.93
395_T	514_L	0.926	0.93
392_R	469_D	0.925	0.93
129_S	141_I	0.924	0.93
358_L	361_R	0.924	0.93
106_V	118_P	0.923	0.93
358_L	364_F	0.923	0.93
340_L	358_L	0.921	0.92
449_H	452_P	0.920	0.92
297_E	304_Y	0.919	0.92
256_T	319_Q	0.911	0.92
27_A	39_I	0.910	0.92
122_G	125_G	0.903	0.92
469_D	474_R	0.902	0.92
299_R	304_Y	0.900	0.92
75_P	86_L	0.897	0.91
368_Y	525_Y	0.893	0.91
362_P	527_D	0.893	0.91
404_F	427_E	0.891	0.91
262_A	293_I	0.891	0.91
162_F	166_T	0.888	0.91
388_H	533_Y	0.885	0.91
80_A	132_H	0.884	0.91
76_C	129_S	0.883	0.91
105_L	162_F	0.882	0.91
13_P	31_F	0.882	0.91
251_L	259_W	0.882	0.91
259_W	298_W	0.881	0.91
267_R	290_E	0.881	0.91
160_Q	171_P	0.877	0.91
190_L	220_I	0.876	0.90
177_F	185_T	0.872	0.90
89_T	103_N	0.871	0.90
474_R	488_P	0.870	0.90
143_R	155_N	0.870	0.90
217_S	223_P	0.867	0.90
202_A	210_H	0.864	0.90
162_F	170_S	0.857	0.90
123_N	169_L	0.854	0.89
12_N	50_L	0.853	0.89
66_N	90_D	0.848	0.89
7_I	17_L	0.847	0.89
316_K	319_Q	0.845	0.89
88_Y	106_V	0.842	0.89
315_V	318_P	0.842	0.89
438_Q	441_H	0.840	0.89
369_G	406_Q	0.840	0.89
463_W	530_Y	0.840	0.89
393_A	466_V	0.839	0.89
301_G	304_Y	0.839	0.89
81_D	85_W	0.835	0.88
17_L	250_S	0.835	0.88
24_Y	42_S	0.831	0.88
49_S	325_A	0.830	0.88
476_S	484_W	0.828	0.88
66_N	92_K	0.827	0.88
169_L	172_E	0.827	0.88
346_T	356_G	0.827	0.88
404_F	428_E	0.823	0.88
260_Y	293_I	0.821	0.87
262_A	291_T	0.819	0.87
79_Y	82_G	0.818	0.87
160_Q	173_R	0.817	0.87
76_C	189_H	0.816	0.87
45_L	262_A	0.816	0.87
311_A	320_V	0.815	0.87
200_M	296_I	0.815	0.87
246_S	263_Y	0.814	0.87
245_K	285_C	0.813	0.87
121_M	166_T	0.808	0.87
473_Y	493_A	0.808	0.87
141_I	188_A	0.807	0.87
17_L	252_L	0.806	0.86
450_E	454_P	0.806	0.86
311_A	318_P	0.803	0.86
451_Q	454_P	0.799	0.86
153_P	184_Y	0.798	0.86
193_H	196_W	0.796	0.86
258_E	319_Q	0.796	0.86
386_W	473_Y	0.794	0.86
143_R	154_H	0.793	0.86
4_T	314_T	0.792	0.85
344_L	531_F	0.791	0.85
356_G	367_L	0.790	0.85
77_L	111_I	0.790	0.85
466_V	473_Y	0.789	0.85
195_G	218_K	0.789	0.85
231_T	234_T	0.784	0.85
158_V	175_T	0.783	0.85
217_S	222_G	0.783	0.85
72_I	89_T	0.781	0.85
314_T	318_P	0.781	0.85
420_S	495_K	0.779	0.85
20_Q	82_G	0.777	0.84
422_C	475_Y	0.776	0.84
451_Q	485_H	0.772	0.84
16_S	77_L	0.767	0.84
325_A	329_G	0.767	0.84
56_D	114_P	0.764	0.83
465_R	478_S	0.760	0.83
42_S	48_W	0.760	0.83
208_Y	285_C	0.758	0.83
105_L	121_M	0.758	0.83
479_F	482_E	0.756	0.83
398_E	460_E	0.755	0.83
21_G	41_H	0.753	0.82
107_T	118_P	0.751	0.82
232_M	296_I	0.751	0.82
321_A	325_A	0.751	0.82
134_D	195_G	0.750	0.82
401_P	406_Q	0.750	0.82
227_H	299_R	0.750	0.82
201_A	213_V	0.749	0.82
404_F	426_Y	0.747	0.82
430_Q	433_T	0.745	0.82
102_R	120_P	0.744	0.82
131_F	220_I	0.742	0.82
309_K	314_T	0.741	0.81
235_S	246_S	0.737	0.81
52_S	56_D	0.736	0.81
407_S	425_D	0.733	0.81
32_E	508_T	0.732	0.81
407_S	423_F	0.731	0.81
12_N	387_Q	0.731	0.81
525_Y	529_D	0.729	0.80
321_A	326_A	0.729	0.80
463_W	481_G	0.729	0.80
453_I	487_V	0.727	0.80
19_R	23_D	0.725	0.80
386_W	391_F	0.722	0.80
87_L	130_L	0.720	0.80
189_H	250_S	0.720	0.80
76_C	141_I	0.719	0.79
227_H	304_Y	0.718	0.79
19_R	252_L	0.717	0.79
220_I	223_P	0.715	0.79
397_M	526_A	0.714	0.79
462_V	479_F	0.714	0.79
363_G	529_D	0.714	0.79
358_L	529_D	0.712	0.79
87_L	128_P	0.712	0.79
384_R	387_Q	0.710	0.79
80_A	138_K	0.708	0.78
68_D	413_Y	0.706	0.78
33_W	508_T	0.706	0.78
433_T	442_N	0.704	0.78
34_F	350_P	0.703	0.78
518_D	526_A	0.702	0.78
309_K	312_Q	0.702	0.78
55_L	88_Y	0.702	0.78
73_W	92_K	0.702	0.78
253_Q	258_E	0.701	0.78
131_F	138_K	0.700	0.78
264_L	290_E	0.699	0.78
299_R	303_P	0.697	0.77
90_D	101_G	0.697	0.77
296_I	305_V	0.694	0.77
142_Y	173_R	0.690	0.77
261_M	294_A	0.688	0.76
410_L	512_V	0.686	0.76
255_H	320_V	0.684	0.76
109_P	114_P	0.684	0.76
196_W	225_E	0.683	0.76
322_E	325_A	0.683	0.76
370_N	380_S	0.682	0.76
19_R	254_T	0.682	0.76
346_T	351_F	0.680	0.76
436_V	439_L	0.679	0.76
164_P	167_G	0.674	0.75
196_W	301_G	0.670	0.75
441_H	444_P	0.670	0.75
3_I	293_I	0.670	0.75
156_T	175_T	0.668	0.74
138_K	162_F	0.668	0.74
72_I	75_P	0.667	0.74
119_I	167_G	0.667	0.74
204_G	213_V	0.667	0.74
475_Y	488_P	0.667	0.74
325_A	328_P	0.666	0.74
249_G	262_A	0.666	0.74
323_Q	326_A	0.666	0.74
25_Y	84_F	0.665	0.74
38_R	50_L	0.664	0.74
39_I	54_P	0.662	0.74
157_I	203_E	0.661	0.74
450_E	453_I	0.658	0.73
35_P	288_G	0.657	0.73
357_S	527_D	0.653	0.73
263_Y	292_G	0.651	0.72
170_S	173_R	0.651	0.72
92_K	102_R	0.650	0.72
245_K	414_Y	0.650	0.72
391_F	412_C	0.650	0.72
182_L	226_L	0.648	0.72
517_E	520_S	0.647	0.72
120_P	123_N	0.647	0.72
364_F	398_E	0.646	0.72
477_Y	484_W	0.646	0.72
59_S	106_V	0.646	0.72
55_L	89_T	0.645	0.72
101_G	120_P	0.645	0.72
312_Q	315_V	0.644	0.72
40_Y	187_G	0.642	0.71
331_W	343_E	0.637	0.71
486_T	489_V	0.637	0.71
103_N	125_G	0.637	0.71
339_S	454_P	0.636	0.71
187_G	212_V	0.634	0.70
248_H	264_L	0.633	0.70
159_L	190_L	0.631	0.70
449_H	455_V	0.631	0.70
404_F	520_S	0.631	0.70
416_S	494_W	0.630	0.70
30_T	35_P	0.630	0.70
227_H	232_M	0.629	0.70
442_N	445_S	0.628	0.70
323_Q	327_V	0.628	0.70
107_T	167_G	0.627	0.70
402_V	524_C	0.626	0.69
48_W	197_Y	0.626	0.69
406_Q	524_C	0.625	0.69
137_R	164_P	0.625	0.69
298_W	302_W	0.624	0.69
29_S	206_T	0.624	0.69
8_L	12_N	0.623	0.69
384_R	388_H	0.623	0.69
31_F	35_P	0.623	0.69
29_S	205_G	0.622	0.69
474_R	489_V	0.621	0.69
368_Y	527_D	0.621	0.69
413_Y	416_S	0.620	0.69
357_S	368_Y	0.618	0.69
226_L	230_V	0.618	0.69
362_P	482_E	0.617	0.68
56_D	108_A	0.617	0.68
410_L	531_F	0.617	0.68
361_R	529_D	0.616	0.68
90_D	102_R	0.616	0.68
360_A	366_R	0.616	0.68
345_Q	385_R	0.614	0.68
410_L	513_G	0.614	0.68
480_D	484_W	0.614	0.68
317_G	326_A	0.614	0.68
212_V	215_L	0.612	0.68
311_A	315_V	0.612	0.68
206_T	210_H	0.611	0.68
358_L	527_D	0.611	0.68
381_T	511_F	0.610	0.68
204_G	210_H	0.609	0.67
334_D	530_Y	0.608	0.67
23_D	51_V	0.608	0.67
439_L	444_P	0.607	0.67
14_D	74_A	0.605	0.67
295_R	306_E	0.605	0.67
123_N	142_Y	0.605	0.67
139_Y	477_Y	0.604	0.67
248_H	290_E	0.604	0.67
320_V	329_G	0.604	0.67
463_W	516_C	0.603	0.67
73_W	88_Y	0.601	0.66
88_Y	104_F	0.601	0.66
425_D	430_Q	0.600	0.66
76_C	250_S	0.600	0.66
73_W	184_Y	0.599	0.66
144_P	155_N	0.599	0.66
208_Y	266_S	0.598	0.66
357_S	525_Y	0.598	0.66
421_Y	515_H	0.598	0.66
210_H	267_R	0.597	0.66
39_I	53_T	0.596	0.66
205_G	210_H	0.595	0.66
422_C	464_L	0.594	0.65
243_L	265_T	0.594	0.65
441_H	487_V	0.593	0.65
296_I	441_H	0.593	0.65
55_L	118_P	0.592	0.65
9_T	290_E	0.592	0.65
420_S	491_Y	0.592	0.65
235_S	263_Y	0.592	0.65
3_I	295_R	0.592	0.65
297_E	306_E	0.592	0.65
395_T	410_L	0.591	0.65
386_W	468_V	0.588	0.65
425_D	429_G	0.588	0.65
199_L	247_G	0.586	0.64
314_T	317_G	0.586	0.64
476_S	488_P	0.585	0.64
9_T	389_F	0.585	0.64
188_A	204_G	0.585	0.64
407_S	517_E	0.584	0.64
436_V	487_V	0.584	0.64
420_S	475_Y	0.583	0.64
140_Y	169_L	0.583	0.64
347_L	383_A	0.582	0.64
287_L	389_F	0.582	0.64
103_N	128_P	0.581	0.64
25_Y	47_N	0.581	0.64
465_R	479_F	0.580	0.64
415_N	439_L	0.580	0.64
399_F	408_A	0.580	0.64
78_S	250_S	0.580	0.64
465_R	480_D	0.580	0.64
425_D	433_T	0.579	0.64
182_L	213_V	0.579	0.64
177_F	181_P	0.578	0.63
219_N	223_P	0.577	0.63
468_V	512_V	0.576	0.63
451_Q	455_V	0.576	0.63
381_T	411_T	0.575	0.63
14_D	29_S	0.574	0.63
362_P	461_S	0.573	0.63
46_K	318_P	0.573	0.63
129_S	189_H	0.573	0.63
333_D	340_L	0.572	0.63
15_P	75_P	0.572	0.63
188_A	201_A	0.572	0.63
184_Y	209_E	0.571	0.62
121_M	162_F	0.570	0.62
139_Y	161_A	0.570	0.62
233_M	305_V	0.569	0.62
455_V	479_F	0.569	0.62
339_S	424_V	0.567	0.62
176_L	199_L	0.566	0.62
108_A	115_W	0.566	0.62
141_I	224_Y	0.565	0.62
409_G	515_H	0.565	0.62
203_E	210_H	0.565	0.62
332_R	530_Y	0.564	0.61
32_E	68_D	0.564	0.61
459_A	462_V	0.564	0.61
369_G	516_C	0.564	0.61
255_H	258_E	0.563	0.61
16_S	28_T	0.563	0.61
411_T	421_Y	0.563	0.61
411_T	437_I	0.562	0.61
205_G	267_R	0.562	0.61
426_Y	432_R	0.562	0.61
198_Y	302_W	0.561	0.61
440_D	444_P	0.560	0.61
158_V	173_R	0.560	0.61
324_P	481_G	0.559	0.61
288_G	298_W	0.559	0.61
453_I	456_P	0.559	0.61
348_R	409_G	0.559	0.61
346_T	382_V	0.559	0.61
432_R	460_E	0.558	0.61
455_V	459_A	0.558	0.61
440_D	443_V	0.558	0.61
45_L	293_I	0.558	0.61
109_P	112_E	0.558	0.61
47_N	322_E	0.558	0.61
378_T	382_V	0.558	0.61
30_T	345_Q	0.557	0.61
309_K	318_P	0.557	0.61
412_C	512_V	0.557	0.61
171_P	221_D	0.555	0.60
295_R	315_V	0.554	0.60
87_L	189_H	0.553	0.60
311_A	317_G	0.553	0.60
288_G	302_W	0.553	0.60
115_W	298_W	0.553	0.60
346_T	349_I	0.552	0.60
81_D	84_F	0.552	0.60
73_W	156_T	0.551	0.60
72_I	86_L	0.550	0.60
208_Y	245_K	0.550	0.60
16_S	189_H	0.549	0.59
157_I	188_A	0.548	0.59
14_D	289_R	0.546	0.59
226_L	231_T	0.546	0.59
79_Y	84_F	0.545	0.59
493_A	510_A	0.545	0.59
324_P	368_Y	0.545	0.59
202_A	247_G	0.544	0.59
103_N	126_F	0.544	0.59
386_W	512_V	0.543	0.59
202_A	249_G	0.543	0.59
83_K	108_A	0.543	0.59
202_A	206_T	0.543	0.59
89_T	124_G	0.543	0.59
108_A	116_S	0.540	0.58
305_V	436_V	0.540	0.58
179_G	213_V	0.538	0.58
105_L	119_I	0.538	0.58
103_N	140_Y	0.536	0.58
321_A	329_G	0.535	0.57
514_L	531_F	0.535	0.57
176_L	220_I	0.535	0.57
184_Y	207_S	0.534	0.57
128_P	223_P	0.534	0.57
51_V	342_P	0.533	0.57
332_R	335_F	0.533	0.57
424_V	432_R	0.533	0.57
157_I	224_Y	0.532	0.57
37_V	55_L	0.532	0.57
203_E	206_T	0.531	0.57
52_S	108_A	0.530	0.57
439_L	443_V	0.530	0.57
398_E	527_D	0.529	0.57
362_P	366_R	0.529	0.57
177_F	182_L	0.529	0.57
474_R	487_V	0.529	0.57
256_T	320_V	0.529	0.57
82_G	107_T	0.528	0.57
30_T	79_Y	0.528	0.57
201_A	215_L	0.528	0.57
144_P	154_H	0.528	0.57
310_H	319_Q	0.527	0.56
523_G	532_T	0.527	0.56
155_N	177_F	0.525	0.56
317_G	320_V	0.525	0.56
235_S	241_N	0.524	0.56
315_V	320_V	0.524	0.56
90_D	100_N	0.524	0.56
321_A	327_V	0.524	0.56
16_S	248_H	0.524	0.56
363_G	527_D	0.522	0.56
364_F	396_R	0.522	0.56
188_A	200_M	0.522	0.56
402_V	405_Q	0.520	0.55
74_A	289_R	0.520	0.55
18_C	77_L	0.520	0.55
429_G	454_P	0.520	0.55
103_N	129_S	0.520	0.55
335_F	344_L	0.519	0.55
129_S	250_S	0.519	0.55
231_T	247_G	0.518	0.55
27_A	89_T	0.518	0.55
340_L	356_G	0.517	0.55
204_G	247_G	0.516	0.55
308_G	311_A	0.515	0.55
16_S	40_Y	0.515	0.55
206_T	247_G	0.514	0.55
232_M	294_A	0.514	0.55
222_G	233_M	0.513	0.54
3_I	317_G	0.513	0.54
269_L	286_P	0.513	0.54
126_F	204_G	0.512	0.54
124_G	142_Y	0.511	0.54
255_H	319_Q	0.511	0.54
143_R	158_V	0.510	0.54
24_Y	366_R	0.510	0.54
416_S	517_E	0.509	0.54
126_F	188_A	0.509	0.54
200_M	303_P	0.508	0.54
459_A	483_T	0.508	0.54
30_T	72_I	0.508	0.54
360_A	527_D	0.507	0.54
363_G	367_L	0.507	0.54
244_Q	508_T	0.506	0.53
449_H	453_I	0.506	0.53
433_T	436_V	0.505	0.53
202_A	212_V	0.504	0.53
438_Q	443_V	0.503	0.53
336_D	358_L	0.503	0.53
25_Y	51_V	0.503	0.53
75_P	79_Y	0.502	0.53
461_S	480_D	0.501	0.53
210_H	264_L	0.501	0.53
27_A	115_W	0.500	0.53

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3c2uA	3	1	100	0.147	Contact Map
1yifA	3	0.9925	100	0.157	Contact Map
2exhA	3	0.9944	100	0.161	Contact Map
1yrzA	1	0.9683	100	0.17	Contact Map
3zxkA	1	0.8937	100	0.259	Contact Map
4kc7A	1	0.694	100	0.493	Contact Map
4kcaA	2	0.7295	100	0.498	Contact Map
2x8sA	1	0.6866	100	0.501	Contact Map
3c7fA	1	0.791	100	0.52	Contact Map
3akhA	1	0.7631	100	0.526	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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