YBCK - ECOLI - GREMLIN Contacts

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YBCK - Uncharacterized protein YbcK

UniProt:	P77698	Sequences: MKKAIAYMRFSSPGQMSGDSLNRQRRLIAEWLKVNSDYYLDTITYEDLGLSAFKGKHAQSGAFSEFLDAIEHGYILPGTTLLVESLDRLSREKVGEAIERLKLILNHGIDVITLCDNTVYNIDSLNEPYSLIKAILIAQRANEESEIKSSRVKLSWKKKRQDALESGTIMTASCPRWLSLDDKRTAFVPDPDRVKTIELIFKLRMERRSLNAIAKYLNDHAVKNFSGKESAWGPSVIEKLLANKALIGICVPSYRARGKGISEIAGYYPRVISDDLFYAVQEIRLAPFGISNSSKNPMLINLLRTVMKCEACGNTMIVHAVSGSLHGYYVCPMRRLHRCDRPSIKRDLVDYNIINELLFNCSKIQPVENKKDANETLELKIIELQMKINNLIVALSVAPEVTAIAEKIRLLDKELRRASVSLKTLKSKGVNSFSDFYAIDLTSKNGRELCRTLAYKTFEKIIINTDNKTCDIYFMNGIVFKHYPLMKVISAQQAISALKYMVDGEIYF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13627
Length:	508 (442)
Sequences:	4824 (4232)
Seq/√Len:	201.3

ECOLI - YBCK
BACSU - YOKA CISA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
199_L	220_H	4.709	1.00
45_Y	69_A	4.428	1.00
273_S	276_L	4.390	1.00
179_S	190_D	3.872	1.00
62_A	65_E	3.567	1.00
203_L	216_Y	3.444	1.00
216_Y	220_H	3.206	1.00
274_D	278_Y	3.161	1.00
205_M	276_L	3.141	1.00
199_L	203_L	2.876	1.00
43_I	65_E	2.719	1.00
6_A	28_I	2.705	1.00
380_K	414_E	2.699	1.00
190_D	193_R	2.605	1.00
308_K	460_K	2.568	1.00
381_I	415_L	2.485	1.00
30_E	34_V	2.456	1.00
205_M	280_V	2.432	1.00
25_R	29_A	2.397	1.00
308_K	315_T	2.384	1.00
8_M	25_R	2.376	1.00
373_A	421_S	2.366	1.00
179_S	188_V	2.327	1.00
374_N	422_L	2.313	1.00
203_L	208_R	2.272	1.00
310_E	464_N	2.267	1.00
70_I	75_I	2.254	1.00
377_L	418_A	2.238	1.00
69_A	74_Y	2.231	1.00
25_R	44_T	2.212	1.00
202_K	276_L	2.207	1.00
249_I	265_A	2.189	1.00
244_K	249_I	2.115	1.00
208_R	216_Y	2.029	1.00
277_F	281_Q	2.026	1.00
249_I	274_D	2.011	1.00
314_N	333_M	1.973	1.00
377_L	422_L	1.964	1.00
346_R	350_D	1.931	1.00
199_L	216_Y	1.925	1.00
238_E	242_A	1.921	1.00
381_I	418_A	1.903	1.00
144_E	151_R	1.898	1.00
131_L	146_E	1.891	1.00
242_A	285_L	1.881	1.00
32_L	39_Y	1.851	1.00
247_I	274_D	1.850	1.00
194_V	198_E	1.809	1.00
384_L	411_L	1.808	1.00
29_A	44_T	1.807	1.00
95_G	102_K	1.793	1.00
384_L	415_L	1.772	1.00
202_K	206_E	1.768	1.00
385_Q	415_L	1.759	1.00
71_E	103_L	1.754	1.00
4_A	37_D	1.741	1.00
47_D	62_A	1.739	1.00
201_F	280_V	1.739	1.00
306_V	455_Y	1.725	1.00
311_A	340_D	1.721	1.00
378_E	426_K	1.712	1.00
189_P	271_V	1.710	1.00
181_D	188_V	1.700	1.00
378_E	422_L	1.692	1.00
26_R	30_E	1.679	1.00
242_A	284_R	1.667	1.00
451_R	455_Y	1.664	1.00
193_R	225_F	1.659	1.00
144_E	148_K	1.622	1.00
113_T	116_D	1.620	1.00
387_K	397_V	1.611	1.00
83_V	111_V	1.600	1.00
5_I	75_I	1.580	1.00
211_N	215_K	1.565	1.00
214_A	237_I	1.546	1.00
396_S	407_K	1.546	1.00
204_R	241_L	1.533	1.00
415_L	419_S	1.524	1.00
409_R	413_K	1.513	1.00
12_S	15_Q	1.505	1.00
201_F	272_I	1.504	1.00
200_I	213_I	1.498	1.00
159_K	168_T	1.497	1.00
270_R	274_D	1.496	1.00
400_E	403_A	1.494	1.00
66_F	81_L	1.491	1.00
32_L	82_L	1.489	1.00
203_L	206_E	1.478	1.00
446_G	449_L	1.476	1.00
417_R	421_S	1.474	1.00
216_Y	219_D	1.465	1.00
31_W	35_N	1.461	1.00
385_Q	419_S	1.452	1.00
404_I	408_I	1.450	1.00
205_M	279_A	1.438	1.00
40_L	43_I	1.436	1.00
278_Y	282_E	1.434	1.00
127_E	130_S	1.430	1.00
303_L	350_D	1.426	1.00
380_K	383_E	1.414	1.00
244_K	247_I	1.414	1.00
135_I	139_Q	1.411	1.00
176_R	196_T	1.407	1.00
356_E	359_F	1.397	1.00
191_P	198_E	1.393	1.00
194_V	271_V	1.393	1.00
25_R	46_E	1.381	1.00
209_S	212_A	1.377	1.00
201_F	246_L	1.375	1.00
142_N	146_E	1.372	1.00
63_F	66_F	1.371	1.00
244_K	251_V	1.368	1.00
265_A	274_D	1.366	1.00
374_N	378_E	1.364	1.00
29_A	33_K	1.363	1.00
373_A	376_T	1.362	1.00
419_S	423_K	1.362	1.00
407_K	410_L	1.356	1.00
210_L	238_E	1.352	1.00
393_V	407_K	1.346	1.00
65_E	69_A	1.336	1.00
410_L	414_E	1.334	1.00
203_L	220_H	1.328	1.00
147_I	151_R	1.327	1.00
189_P	194_V	1.327	1.00
5_I	66_F	1.324	1.00
157_K	161_Q	1.310	1.00
218_N	232_W	1.304	1.00
214_A	218_N	1.301	1.00
374_N	426_K	1.298	1.00
233_G	236_V	1.298	1.00
200_I	217_L	1.297	1.00
28_I	82_L	1.288	1.00
97_A	138_A	1.288	1.00
68_D	72_H	1.280	1.00
70_I	81_L	1.278	1.00
200_I	240_L	1.272	1.00
283_I	287_P	1.267	1.00
241_L	280_V	1.258	1.00
301_N	318_V	1.255	1.00
181_D	184_R	1.250	1.00
132_I	143_E	1.241	1.00
101_L	134_A	1.241	1.00
6_A	39_Y	1.237	1.00
247_I	277_F	1.228	1.00
382_I	385_Q	1.223	1.00
149_S	153_K	1.222	1.00
384_L	418_A	1.220	1.00
83_V	113_T	1.217	1.00
389_N	410_L	1.205	1.00
421_S	424_T	1.197	1.00
351_Y	355_N	1.197	1.00
145_S	148_K	1.194	1.00
70_I	109_I	1.193	1.00
215_K	219_D	1.190	1.00
97_A	101_L	1.187	1.00
272_I	280_V	1.179	1.00
250_C	267_Y	1.178	1.00
87_D	141_A	1.168	1.00
128_P	150_S	1.167	1.00
8_M	21_L	1.163	1.00
422_L	426_K	1.163	1.00
329_Y	346_R	1.161	1.00
45_Y	66_F	1.158	1.00
204_R	284_R	1.155	1.00
319_H	330_V	1.155	1.00
196_T	222_V	1.152	1.00
377_L	421_S	1.149	1.00
414_E	417_R	1.142	1.00
384_L	414_E	1.141	1.00
381_I	422_L	1.141	1.00
195_K	198_E	1.139	1.00
374_N	425_L	1.137	1.00
145_S	149_S	1.136	1.00
208_R	212_A	1.134	1.00
364_I	370_K	1.122	1.00
87_D	151_R	1.119	1.00
307_M	349_V	1.117	1.00
389_N	406_E	1.115	1.00
200_I	237_I	1.114	1.00
345_K	348_L	1.113	1.00
8_M	44_T	1.110	1.00
132_I	140_R	1.109	1.00
6_A	44_T	1.106	1.00
214_A	234_P	1.106	1.00
381_I	419_S	1.105	1.00
388_I	415_L	1.105	1.00
395_L	401_V	1.104	1.00
462_I	473_Y	1.098	1.00
5_I	45_Y	1.096	1.00
85_S	151_R	1.094	1.00
10_F	15_Q	1.091	1.00
224_N	227_G	1.087	1.00
334_R	339_C	1.084	1.00
255_R	258_G	1.081	1.00
71_E	107_H	1.079	1.00
204_R	283_I	1.079	1.00
132_I	139_Q	1.075	1.00
375_E	378_E	1.074	1.00
416_R	419_S	1.071	1.00
30_E	33_K	1.062	1.00
276_L	280_V	1.062	1.00
249_I	266_G	1.061	1.00
181_D	186_A	1.058	1.00
169_I	187_F	1.055	1.00
158_K	166_S	1.052	1.00
86_L	141_A	1.049	1.00
86_L	134_A	1.049	1.00
7_Y	47_D	1.047	1.00
68_D	71_E	1.042	1.00
241_L	281_Q	1.041	1.00
197_I	201_F	1.039	1.00
50_L	57_H	1.036	1.00
388_I	408_I	1.036	1.00
413_K	417_R	1.035	1.00
390_N	395_L	1.032	1.00
310_E	462_I	1.028	1.00
67_L	100_R	1.027	1.00
116_D	137_I	1.025	1.00
95_G	99_E	1.021	1.00
416_R	420_V	1.014	1.00
201_F	277_F	1.013	1.00
395_L	404_I	1.013	1.00
192_D	195_K	1.013	1.00
283_I	286_A	1.013	1.00
462_I	471_D	1.012	1.00
203_L	213_I	1.011	1.00
276_L	279_A	1.010	1.00
179_S	191_P	1.009	1.00
84_E	154_L	1.009	1.00
86_L	113_T	1.000	1.00
178_L	246_L	1.000	1.00
56_K	145_S	0.996	1.00
421_S	425_L	0.994	1.00
418_A	422_L	0.990	1.00
247_I	278_Y	0.989	1.00
460_K	473_Y	0.988	1.00
223_K	231_A	0.983	1.00
148_K	155_S	0.979	1.00
4_A	80_T	0.978	1.00
105_L	131_L	0.975	1.00
52_A	90_S	0.973	1.00
196_T	200_I	0.972	1.00
210_L	214_A	0.971	0.99
205_M	283_I	0.969	0.99
98_I	135_I	0.969	0.99
92_E	142_N	0.968	0.99
144_E	147_I	0.964	0.99
100_R	104_I	0.958	0.99
326_H	345_K	0.957	0.99
407_K	411_L	0.955	0.99
327_G	346_R	0.954	0.99
63_F	100_R	0.953	0.99
27_L	84_E	0.950	0.99
50_L	61_G	0.950	0.99
464_N	471_D	0.947	0.99
316_M	341_R	0.947	0.99
198_E	276_L	0.942	0.99
384_L	387_K	0.941	0.99
158_K	161_Q	0.940	0.99
89_L	100_R	0.939	0.99
46_E	62_A	0.939	0.99
204_R	213_I	0.937	0.99
392_I	396_S	0.935	0.99
199_L	202_K	0.935	0.99
223_K	232_W	0.934	0.99
328_Y	345_K	0.934	0.99
197_I	271_V	0.932	0.99
354_I	358_L	0.931	0.99
364_I	367_V	0.930	0.99
403_A	412_D	0.929	0.99
302_L	454_A	0.928	0.99
156_W	159_K	0.927	0.99
81_L	104_I	0.926	0.99
390_N	398_A	0.923	0.99
373_A	425_L	0.917	0.99
63_F	96_E	0.917	0.99
155_S	159_K	0.915	0.99
458_F	461_I	0.915	0.99
101_L	105_L	0.912	0.99
401_V	405_A	0.909	0.99
307_M	329_Y	0.908	0.99
387_K	396_S	0.908	0.99
213_I	237_I	0.901	0.99
80_T	112_I	0.900	0.99
303_L	346_R	0.900	0.99
282_E	286_A	0.896	0.99
131_L	142_N	0.895	0.99
5_I	69_A	0.893	0.99
316_M	463_I	0.892	0.99
397_V	401_V	0.890	0.99
217_L	232_W	0.888	0.99
388_I	412_D	0.887	0.99
388_I	411_L	0.886	0.99
309_C	312_C	0.884	0.99
63_F	89_L	0.883	0.99
210_L	237_I	0.882	0.99
32_L	37_D	0.881	0.99
118_T	130_S	0.879	0.99
196_T	199_L	0.878	0.99
405_A	409_R	0.876	0.99
10_F	20_S	0.875	0.99
8_M	46_E	0.873	0.99
382_I	386_M	0.873	0.99
218_N	231_A	0.872	0.99
279_A	282_E	0.871	0.99
383_E	387_K	0.870	0.99
277_F	280_V	0.870	0.99
306_V	454_A	0.869	0.99
435_D	438_A	0.867	0.99
251_V	254_Y	0.867	0.99
383_E	397_V	0.864	0.99
187_F	245_A	0.859	0.99
148_K	152_V	0.859	0.99
197_I	246_L	0.857	0.99
381_I	384_L	0.857	0.99
67_L	103_L	0.855	0.99
412_D	416_R	0.851	0.99
207_R	213_I	0.850	0.99
178_L	189_P	0.850	0.99
459_E	473_Y	0.849	0.99
197_I	240_L	0.848	0.99
151_R	154_L	0.848	0.99
360_N	363_K	0.848	0.99
110_D	119_V	0.847	0.99
31_W	82_L	0.844	0.99
380_K	384_L	0.844	0.99
149_S	152_V	0.841	0.99
37_D	82_L	0.841	0.99
210_L	284_R	0.840	0.99
222_V	232_W	0.839	0.99
247_I	270_R	0.839	0.99
70_I	104_I	0.836	0.98
201_F	205_M	0.836	0.98
384_L	388_I	0.834	0.98
394_A	399_P	0.833	0.98
378_E	382_I	0.833	0.98
255_R	259_K	0.831	0.98
103_L	107_H	0.831	0.98
204_R	287_P	0.831	0.98
83_V	89_L	0.830	0.98
4_A	32_L	0.829	0.98
301_N	304_R	0.827	0.98
90_S	97_A	0.825	0.98
312_C	331_C	0.822	0.98
202_K	205_M	0.822	0.98
28_I	114_L	0.822	0.98
313_G	462_I	0.821	0.98
420_V	424_T	0.819	0.98
69_A	75_I	0.818	0.98
136_L	139_Q	0.816	0.98
15_Q	18_G	0.814	0.98
301_N	329_Y	0.812	0.98
152_V	156_W	0.810	0.98
243_N	246_L	0.809	0.98
195_K	202_K	0.805	0.98
196_T	217_L	0.802	0.98
246_L	272_I	0.795	0.98
86_L	116_D	0.793	0.98
247_I	273_S	0.793	0.98
168_T	185_T	0.793	0.98
97_A	134_A	0.792	0.98
390_N	394_A	0.790	0.98
391_L	396_S	0.784	0.98
67_L	71_E	0.783	0.98
347_D	351_Y	0.783	0.98
57_H	64_S	0.781	0.98
58_A	90_S	0.780	0.98
418_A	421_S	0.779	0.98
176_R	193_R	0.779	0.98
309_C	331_C	0.778	0.98
454_A	458_F	0.778	0.98
134_A	138_A	0.778	0.98
176_R	232_W	0.777	0.98
37_D	80_T	0.777	0.98
420_V	423_K	0.776	0.98
189_P	269_P	0.774	0.98
43_I	74_Y	0.774	0.98
80_T	110_D	0.774	0.98
97_A	105_L	0.771	0.97
423_K	426_K	0.771	0.97
318_V	327_G	0.771	0.97
133_K	137_I	0.771	0.97
311_A	465_T	0.767	0.97
51_S	57_H	0.767	0.97
212_A	215_K	0.767	0.97
45_Y	74_Y	0.765	0.97
85_S	147_I	0.765	0.97
223_K	227_G	0.763	0.97
191_P	195_K	0.762	0.97
19_D	22_N	0.760	0.97
246_L	280_V	0.760	0.97
328_Y	343_S	0.759	0.97
85_S	116_D	0.758	0.97
70_I	107_H	0.758	0.97
59_Q	64_S	0.757	0.97
376_T	380_K	0.754	0.97
388_I	392_I	0.753	0.97
377_L	381_I	0.752	0.97
303_L	307_M	0.752	0.97
388_I	403_A	0.751	0.97
182_D	188_V	0.749	0.97
129_Y	132_I	0.748	0.97
302_L	350_D	0.748	0.97
160_R	252_P	0.748	0.97
303_L	353_I	0.747	0.97
92_E	102_K	0.746	0.97
276_L	283_I	0.745	0.97
411_L	415_L	0.745	0.97
255_R	261_I	0.745	0.97
399_P	405_A	0.745	0.97
235_S	239_K	0.743	0.97
95_G	98_I	0.743	0.97
217_L	237_I	0.743	0.97
178_L	270_R	0.742	0.97
132_I	135_I	0.742	0.97
98_I	102_K	0.739	0.97
177_W	246_L	0.739	0.97
242_A	281_Q	0.737	0.97
408_I	412_D	0.735	0.97
214_A	232_W	0.733	0.97
385_Q	389_N	0.729	0.96
23_R	158_K	0.726	0.96
249_I	267_Y	0.726	0.96
39_Y	44_T	0.725	0.96
458_F	472_I	0.724	0.96
6_A	25_R	0.723	0.96
302_L	329_Y	0.723	0.96
393_V	401_V	0.722	0.96
174_C	187_F	0.721	0.96
318_V	346_R	0.721	0.96
303_L	461_I	0.720	0.96
387_K	411_L	0.719	0.96
224_N	232_W	0.718	0.96
390_N	393_V	0.718	0.96
282_E	285_L	0.717	0.96
85_S	137_I	0.715	0.96
210_L	234_P	0.714	0.96
8_M	28_I	0.712	0.96
75_I	109_I	0.712	0.96
237_I	240_L	0.711	0.96
45_Y	65_E	0.710	0.96
135_I	138_A	0.709	0.96
322_S	325_L	0.709	0.96
403_A	408_I	0.708	0.96
442_T	450_C	0.707	0.96
174_C	180_L	0.706	0.96
281_Q	284_R	0.706	0.96
23_R	27_L	0.705	0.96
182_D	185_T	0.703	0.96
201_F	276_L	0.700	0.96
392_I	403_A	0.700	0.96
31_W	37_D	0.698	0.95
21_L	48_L	0.698	0.95
390_N	396_S	0.693	0.95
58_A	63_F	0.692	0.95
350_D	354_I	0.689	0.95
152_V	155_S	0.687	0.95
302_L	447_R	0.687	0.95
84_E	115_C	0.686	0.95
285_L	288_F	0.684	0.95
318_V	329_Y	0.682	0.95
195_K	199_L	0.681	0.95
10_F	18_G	0.679	0.95
26_R	158_K	0.679	0.95
255_R	260_G	0.675	0.95
23_R	154_L	0.671	0.94
447_R	450_C	0.671	0.94
39_Y	43_I	0.668	0.94
380_K	418_A	0.666	0.94
89_L	111_V	0.666	0.94
308_K	462_I	0.663	0.94
266_G	269_P	0.663	0.94
194_V	197_I	0.659	0.94
247_I	251_V	0.658	0.94
198_E	202_K	0.656	0.94
43_I	69_A	0.652	0.93
98_I	105_L	0.651	0.93
212_A	216_Y	0.649	0.93
371_K	429_G	0.648	0.93
133_K	140_R	0.647	0.93
381_I	385_Q	0.647	0.93
66_F	69_A	0.646	0.93
307_M	461_I	0.645	0.93
20_S	24_Q	0.645	0.93
196_T	232_W	0.640	0.93
32_L	36_S	0.639	0.93
25_R	28_I	0.639	0.93
130_S	137_I	0.638	0.93
204_R	210_L	0.637	0.93
258_G	261_I	0.634	0.93
330_V	335_R	0.633	0.92
179_S	193_R	0.630	0.92
176_R	197_I	0.630	0.92
380_K	421_S	0.629	0.92
23_R	84_E	0.628	0.92
161_Q	166_S	0.627	0.92
5_I	40_L	0.624	0.92
135_I	140_R	0.624	0.92
275_D	279_A	0.623	0.92
386_M	390_N	0.620	0.92
272_I	276_L	0.620	0.92
141_A	151_R	0.616	0.91
159_K	170_M	0.616	0.91
406_E	410_L	0.616	0.91
393_V	397_V	0.615	0.91
136_L	140_R	0.615	0.91
132_I	136_L	0.613	0.91
357_L	457_T	0.613	0.91
190_D	195_K	0.613	0.91
424_T	428_K	0.613	0.91
365_Q	368_E	0.611	0.91
419_S	422_L	0.610	0.91
204_R	209_S	0.610	0.91
97_A	100_R	0.608	0.91
99_E	104_I	0.608	0.91
157_K	160_R	0.608	0.91
133_K	139_Q	0.608	0.91
143_E	146_E	0.607	0.91
200_I	232_W	0.606	0.91
148_K	151_R	0.605	0.91
266_G	274_D	0.605	0.91
355_N	359_F	0.602	0.90
307_M	316_M	0.600	0.90
98_I	101_L	0.600	0.90
180_L	185_T	0.600	0.90
140_R	147_I	0.599	0.90
391_L	404_I	0.597	0.90
156_W	160_R	0.597	0.90
110_D	121_N	0.597	0.90
133_K	136_L	0.594	0.90
4_A	82_L	0.594	0.90
169_I	175_P	0.593	0.90
279_A	283_I	0.590	0.90
52_A	91_R	0.590	0.90
447_R	451_R	0.589	0.90
143_E	147_I	0.589	0.90
95_G	105_L	0.588	0.89
383_E	386_M	0.585	0.89
64_S	67_L	0.583	0.89
334_R	342_P	0.581	0.89
317_I	332_P	0.580	0.89
120_Y	134_A	0.580	0.89
90_S	96_E	0.579	0.89
218_N	224_N	0.578	0.89
333_M	338_R	0.578	0.89
13_P	48_L	0.577	0.89
6_A	29_A	0.577	0.89
445_N	449_L	0.577	0.89
197_I	280_V	0.577	0.89
300_I	304_R	0.576	0.88
278_Y	281_Q	0.574	0.88
422_L	429_G	0.574	0.88
119_V	127_E	0.573	0.88
84_E	151_R	0.572	0.88
386_M	389_N	0.572	0.88
393_V	396_S	0.572	0.88
353_I	356_E	0.572	0.88
191_P	194_V	0.572	0.88
394_A	407_K	0.571	0.88
14_G	17_S	0.570	0.88
240_L	246_L	0.570	0.88
82_L	112_I	0.569	0.88
302_L	451_R	0.568	0.88
5_I	81_L	0.567	0.88
69_A	72_H	0.566	0.88
238_E	284_R	0.565	0.88
129_Y	143_E	0.565	0.88
104_I	109_I	0.565	0.88
204_R	280_V	0.565	0.88
96_E	102_K	0.564	0.87
436_F	439_I	0.564	0.87
446_G	450_C	0.563	0.87
375_E	379_L	0.563	0.87
264_I	267_Y	0.560	0.87
453_L	457_T	0.558	0.87
102_K	106_N	0.557	0.87
32_L	40_L	0.557	0.87
377_L	380_K	0.556	0.87
245_A	269_P	0.556	0.87
89_L	104_I	0.556	0.87
100_R	105_L	0.556	0.87
37_D	79_T	0.555	0.87
210_L	241_L	0.554	0.87
395_L	408_I	0.554	0.87
99_E	103_L	0.552	0.86
234_P	238_E	0.550	0.86
73_G	109_I	0.550	0.86
86_L	138_A	0.549	0.86
413_K	416_R	0.547	0.86
344_I	349_V	0.547	0.86
211_N	234_P	0.547	0.86
402_T	412_D	0.544	0.86
96_E	99_E	0.543	0.85
101_L	138_A	0.543	0.85
363_K	367_V	0.542	0.85
250_C	264_I	0.542	0.85
247_I	272_I	0.542	0.85
221_A	224_N	0.541	0.85
127_E	131_L	0.539	0.85
19_D	155_S	0.539	0.85
381_I	388_I	0.536	0.85
18_G	48_L	0.536	0.85
207_R	283_I	0.535	0.85
31_W	34_V	0.535	0.85
244_K	254_Y	0.535	0.85
199_L	222_V	0.535	0.85
223_K	228_K	0.534	0.84
47_D	50_L	0.534	0.84
378_E	381_I	0.534	0.84
321_V	324_S	0.533	0.84
131_L	135_I	0.533	0.84
52_A	96_E	0.531	0.84
199_L	217_L	0.530	0.84
410_L	413_K	0.528	0.84
410_L	417_R	0.527	0.84
27_L	154_L	0.526	0.84
69_A	73_G	0.526	0.84
245_A	268_Y	0.526	0.84
417_R	420_V	0.525	0.83
96_E	105_L	0.525	0.83
4_A	39_Y	0.525	0.83
224_N	228_K	0.525	0.83
250_C	268_Y	0.525	0.83
63_F	67_L	0.523	0.83
428_K	431_N	0.522	0.83
426_K	430_V	0.522	0.83
228_K	231_A	0.521	0.83
173_S	226_S	0.521	0.83
205_M	277_F	0.521	0.83
157_K	253_S	0.521	0.83
10_F	49_G	0.520	0.83
137_I	140_R	0.520	0.83
365_Q	369_N	0.518	0.83
332_P	336_L	0.518	0.83
387_K	393_V	0.518	0.83
189_P	195_K	0.518	0.83
188_V	191_P	0.518	0.83
112_I	119_V	0.516	0.82
67_L	99_E	0.515	0.82
385_Q	388_I	0.514	0.82
20_S	23_R	0.514	0.82
101_L	104_I	0.513	0.82
209_S	215_K	0.513	0.82
400_E	412_D	0.513	0.82
329_Y	350_D	0.512	0.82
374_N	377_L	0.512	0.82
43_I	62_A	0.511	0.82
10_F	16_M	0.510	0.82
10_F	23_R	0.507	0.81
51_S	56_K	0.507	0.81
155_S	158_K	0.506	0.81
189_P	193_R	0.506	0.81
137_I	147_I	0.506	0.81
35_N	82_L	0.506	0.81
60_S	177_W	0.505	0.81
85_S	115_C	0.504	0.81
21_L	46_E	0.503	0.81
31_W	112_I	0.503	0.81
147_I	154_L	0.502	0.81
441_L	445_N	0.502	0.81
208_R	213_I	0.501	0.81
216_Y	221_A	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bqqA	2	0.5512	100	0.41	Contact Map
4kisA	2	0.6122	100	0.516	Contact Map
2r0qC	3	0.374	100	0.646	Contact Map
1gdtA	2	0.3602	100	0.673	Contact Map
3guvA	2	0.2874	100	0.677	Contact Map
3g13A	2	0.3031	100	0.678	Contact Map
3uj3X	2	0.2441	100	0.696	Contact Map
3bvpA	4	0.2638	100	0.73	Contact Map
2gm5A	4	0.2441	100	0.745	Contact Map
3lhkA	2	0.2874	100	0.746	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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