GREMLIN Database
SUFD - FeS cluster assembly protein SufD
UniProt: P77689 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13963
Length: 423 (394)
Sequences: 3174 (1802)
Seq/√Len: 90.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
147_R182_E5.0641.00
235_L239_A4.6271.00
144_R179_E4.5591.00
144_R178_A4.4141.00
177_L181_A4.3941.00
177_L213_L4.3201.00
209_A237_E4.0331.00
179_E209_A3.8721.00
209_A236_A3.7061.00
381_N384_D3.6451.00
210_N238_D3.6201.00
207_V211_A3.4431.00
182_E212_H3.4361.00
276_P309_G3.3581.00
108_V140_I3.3171.00
179_E208_A3.2061.00
294_F325_K3.1791.00
207_V241_A3.1051.00
109_S112_D3.0541.00
238_D265_N3.0521.00
233_L241_A3.0141.00
180_G210_N3.0091.00
141_A178_A2.9871.00
382_Q386_Q2.9751.00
264_E294_F2.9191.00
183_A213_L2.8201.00
207_V239_A2.7481.00
274_A303_T2.7261.00
264_E293_G2.6621.00
289_E320_A2.6241.00
212_H240_T2.5701.00
205_I213_L2.5191.00
145_G180_G2.4941.00
130_T172_R2.4751.00
324_I353_A2.4071.00
23_T27_P2.3851.00
234_L262_N2.3491.00
153_L188_H2.2371.00
290_H297_S2.2041.00
267_T296_N2.1851.00
325_K355_D2.1781.00
177_L211_A2.1691.00
310_R342_E2.1301.00
310_R344_D2.1251.00
107_E141_A2.1031.00
207_V213_L2.0731.00
308_K340_L2.0721.00
34_Q38_R2.0681.00
99_D103_G2.0641.00
376_R382_Q2.0471.00
240_T267_T2.0251.00
32_H131_E2.0181.00
207_V235_L1.9761.00
237_E264_E1.9641.00
28_Q131_E1.9591.00
262_N291_N1.9271.00
152_L183_A1.9131.00
329_Q359_S1.9121.00
264_E292_K1.8731.00
305_V309_G1.8721.00
175_L185_V1.8551.00
177_L183_A1.8531.00
250_G253_L1.8051.00
142_V183_A1.7761.00
298_R327_D1.7521.00
197_H225_S1.7101.00
261_L295_C1.7011.00
141_A176_D1.6661.00
367_I389_I1.6421.00
51_Y54_L1.5971.00
107_E143_K1.5521.00
90_D159_Q1.5261.00
345_T362_A1.5171.00
276_P282_C1.5071.00
33_L37_L1.4971.00
319_V358_C1.4761.00
296_N327_D1.4721.00
25_R114_R1.4681.00
104_S149_A1.4560.99
279_N308_K1.4470.99
291_N320_A1.4420.99
215_H241_A1.4350.99
265_N294_F1.4330.99
260_Q289_E1.4220.99
266_S292_K1.4130.99
266_S295_C1.4070.99
35_Q38_R1.3860.99
324_I355_D1.3830.99
27_P31_Q1.3810.99
311_A343_V1.3790.99
292_K295_C1.3610.99
26_S30_Q1.3550.99
117_L120_A1.3470.99
272_S301_H1.3470.99
259_T268_L1.3320.99
113_D139_H1.3270.99
332_N345_T1.3240.99
99_D102_E1.3110.99
326_T356_V1.3110.99
322_H353_A1.3040.99
236_A263_G1.3020.99
237_E265_N1.2940.99
281_V312_V1.2920.99
156_H189_F1.2780.99
305_V343_V1.2540.98
236_A239_A1.2530.98
184_T216_I1.2500.98
304_I394_A1.2480.98
49_W52_T1.2370.98
52_T252_V1.2320.98
278_K307_D1.2280.98
317_I328_G1.2250.98
184_T214_Q1.2160.98
109_S136_S1.2150.98
273_L394_A1.2080.98
106_Y142_V1.2000.98
175_L205_I1.1990.98
47_E51_Y1.1960.98
284_T301_H1.1900.98
103_G106_Y1.1860.98
31_Q34_Q1.1830.98
34_Q37_L1.1800.98
87_V90_D1.1690.98
209_A238_D1.1640.98
323_A326_T1.1620.97
314_N346_K1.1570.97
142_V148_P1.1390.97
319_V326_T1.1380.97
47_E50_K1.1240.97
252_V281_V1.1180.97
130_T202_R1.1160.97
235_L241_A1.1100.97
35_Q39_T1.1090.97
73_Q76_A1.1030.97
112_D116_G1.1010.97
53_P56_G1.0920.96
105_G146_Q1.0910.96
170_H200_G1.0880.96
260_Q291_N1.0870.96
210_N265_N1.0850.96
235_L259_T1.0850.96
81_L84_V1.0800.96
221_E227_H1.0790.96
23_T26_S1.0770.96
295_C326_T1.0770.96
106_Y146_Q1.0760.96
25_R134_A1.0650.96
345_T364_V1.0610.96
118_P121_I1.0560.96
214_Q242_F1.0550.96
380_I388_M1.0500.95
51_Y60_S1.0480.95
31_Q35_Q1.0470.95
204_T232_D1.0420.95
28_Q31_Q1.0420.95
54_L57_L1.0390.95
110_I121_I1.0390.95
142_V177_L1.0390.95
71_P74_R1.0320.95
120_A139_H1.0320.95
148_P183_A1.0310.95
54_L126_F1.0270.95
82_D150_K1.0260.95
259_T270_I1.0140.94
145_G210_N1.0130.94
237_E263_G1.0090.94
215_H243_S1.0080.94
70_S73_Q1.0070.94
53_P60_S1.0040.94
143_K146_Q1.0010.94
317_I326_T1.0000.94
41_L126_F1.0000.94
334_N345_T1.0000.94
234_L260_Q0.9930.94
157_I190_V0.9910.94
172_R202_R0.9890.94
285_R314_N0.9840.94
173_H203_F0.9820.93
124_E256_N0.9800.93
318_N352_Y0.9800.93
111_N136_S0.9760.93
30_Q34_Q0.9700.93
107_E139_H0.9690.93
165_E195_A0.9690.93
319_V330_M0.9650.93
131_E172_R0.9600.93
236_A262_N0.9590.93
293_G324_I0.9570.93
53_P57_L0.9490.92
53_P59_N0.9490.92
176_D206_N0.9470.92
86_L138_T0.9370.92
187_E215_H0.9320.92
108_V152_L0.9310.92
126_F228_F0.9300.91
256_N285_R0.9290.91
44_R53_P0.9280.91
401_L407_K0.9260.91
213_L241_A0.9260.91
172_R204_T0.9240.91
244_H271_N0.9230.91
289_E318_N0.9230.91
128_H204_T0.9170.91
147_R180_G0.9170.91
255_H284_T0.9120.91
36_L125_V0.9100.91
67_G71_P0.9090.91
27_P30_Q0.9030.90
351_I356_V0.9030.90
140_I152_L0.9020.90
349_L358_C0.9010.90
407_K411_L0.9010.90
40_G125_V0.9010.90
114_R117_L0.8980.90
261_L292_K0.8970.90
337_M373_F0.8970.90
139_H176_D0.8940.90
143_K176_D0.8920.90
47_E52_T0.8890.90
312_V346_K0.8890.90
246_F410_V0.8850.89
319_V351_I0.8840.89
43_T46_H0.8830.89
308_K338_G0.8800.89
171_Y201_A0.8780.89
181_A213_L0.8760.89
52_T281_V0.8750.89
235_L268_L0.8720.89
327_D357_K0.8720.89
330_M349_L0.8680.88
50_K53_P0.8670.88
251_A279_N0.8670.88
353_A356_V0.8630.88
174_H204_T0.8630.88
69_I73_Q0.8590.88
179_E210_N0.8570.88
178_A208_A0.8540.88
50_K54_L0.8420.87
74_R77_L0.8420.87
316_L348_Q0.8420.87
189_F227_H0.8420.87
174_H206_N0.8350.86
306_S338_G0.8340.86
330_M358_C0.8340.86
144_R209_A0.8330.86
88_F93_Y0.8320.86
219_A249_G0.8300.86
48_N54_L0.8240.86
305_V311_A0.8220.86
74_R83_S0.8200.85
261_L365_G0.8170.85
236_A266_S0.8150.85
177_L207_V0.8150.85
333_N363_T0.8140.85
299_Q317_I0.8140.85
348_Q352_Y0.8100.85
75_D79_L0.8090.85
285_R334_N0.8080.85
106_Y148_P0.8070.84
404_E407_K0.7990.84
76_A79_L0.7980.84
49_W54_L0.7960.84
286_T299_Q0.7910.83
205_I241_A0.7900.83
217_K229_A0.7890.83
294_F324_I0.7890.83
156_H187_E0.7890.83
305_V341_A0.7890.83
137_V173_H0.7880.83
404_E408_Q0.7860.83
92_R95_P0.7850.83
145_G179_E0.7830.83
328_G358_C0.7810.82
68_E71_P0.7790.82
156_H173_H0.7780.82
286_T301_H0.7730.82
199_T221_E0.7720.82
41_L54_L0.7690.82
129_L404_E0.7680.81
277_V280_E0.7670.81
217_K227_H0.7660.81
269_R298_R0.7650.81
208_A236_A0.7620.81
117_L121_I0.7610.81
217_K221_E0.7610.81
293_G323_A0.7600.81
262_N292_K0.7560.80
49_W59_N0.7550.80
375_L389_I0.7550.80
351_I358_C0.7530.80
348_Q359_S0.7510.80
256_N314_N0.7500.80
114_R121_I0.7490.80
276_P305_V0.7470.80
110_I114_R0.7440.79
275_M414_I0.7430.79
287_W318_N0.7410.79
265_N292_K0.7380.79
49_W57_L0.7370.79
148_P151_P0.7360.79
66_A70_S0.7360.79
277_V307_D0.7360.79
131_E202_R0.7350.79
219_A250_G0.7300.78
100_A103_G0.7290.78
288_L297_S0.7280.78
319_V327_D0.7270.78
271_N400_A0.7260.78
318_N350_E0.7240.77
292_K322_H0.7240.77
362_A390_I0.7220.77
249_G253_L0.7220.77
33_L133_L0.7200.77
395_A411_L0.7180.77
233_L259_T0.7180.77
314_N348_Q0.7170.77
230_H258_S0.7170.77
299_Q302_K0.7160.77
158_T169_A0.7140.76
87_V98_S0.7130.76
187_E217_K0.7130.76
275_M306_S0.7110.76
266_S293_G0.7100.76
172_R365_G0.7090.76
35_Q122_Q0.7090.76
142_V181_A0.7070.76
325_K353_A0.7060.76
335_L390_I0.7060.76
104_S148_P0.7050.76
29_A32_H0.7040.75
84_V150_K0.7030.75
325_K354_D0.7020.75
89_V93_Y0.7020.75
113_D137_V0.7010.75
304_I335_L0.7000.75
72_Q77_L0.7000.75
335_L342_E0.6980.75
316_L350_E0.6980.75
66_A72_Q0.6970.75
219_A280_E0.6970.75
101_T148_P0.6950.75
41_L49_W0.6950.75
32_H128_H0.6930.74
321_Q324_I0.6920.74
319_V350_E0.6900.74
270_I288_L0.6820.73
143_K178_A0.6810.73
124_E230_H0.6790.73
117_L139_H0.6760.73
281_V310_R0.6760.73
52_T312_V0.6730.72
264_E325_K0.6720.72
324_I354_D0.6710.72
307_D338_G0.6710.72
54_L60_S0.6690.72
88_F156_H0.6690.72
375_L380_I0.6690.72
138_T173_H0.6680.72
293_G299_Q0.6670.72
234_L259_T0.6670.72
395_A399_E0.6660.71
82_D86_L0.6650.71
183_A207_V0.6640.71
138_T154_L0.6640.71
301_H332_N0.6630.71
358_C361_G0.6630.71
238_D264_E0.6620.71
380_I385_A0.6620.71
247_L284_T0.6620.71
323_A353_A0.6600.71
113_D120_A0.6600.71
89_V94_V0.6580.70
219_A247_L0.6550.70
209_A265_N0.6550.70
33_L36_L0.6540.70
21_E30_Q0.6540.70
253_L282_C0.6530.70
78_A83_S0.6510.70
88_F91_G0.6470.69
351_I355_D0.6460.69
261_L266_S0.6450.69
51_Y57_L0.6450.69
326_T353_A0.6400.68
272_S284_T0.6400.68
123_A127_L0.6390.68
75_D78_A0.6380.68
206_N234_L0.6360.68
73_Q77_L0.6360.68
255_H301_H0.6330.68
129_L170_H0.6320.67
220_F413_R0.6320.67
352_Y365_G0.6310.67
209_A239_A0.6300.67
66_A69_I0.6300.67
70_S77_L0.6300.67
47_E54_L0.6300.67
89_V157_I0.6250.67
110_I134_A0.6240.66
308_K341_A0.6230.66
188_H220_F0.6230.66
203_F244_H0.6210.66
316_L330_M0.6200.66
72_Q76_A0.6190.66
349_L356_V0.6190.66
121_I139_H0.6190.66
270_I328_G0.6190.66
319_V356_V0.6180.66
231_N257_T0.6170.66
223_P278_K0.6160.65
398_T414_I0.6150.65
359_S365_G0.6130.65
321_Q340_L0.6120.65
233_L239_A0.6120.65
86_L92_R0.6110.65
58_I414_I0.6110.65
353_A358_C0.6110.65
314_N343_V0.6080.64
203_F215_H0.6060.64
82_D85_R0.6060.64
312_V315_G0.6050.64
403_D406_L0.6040.64
326_T358_C0.6040.64
321_Q352_Y0.6040.64
154_L157_I0.6040.64
259_T365_G0.6020.64
303_T332_N0.6010.64
237_E294_F0.6010.64
346_K359_S0.6010.64
241_A259_T0.6010.64
328_G334_N0.6000.63
47_E324_I0.5970.63
365_G368_D0.5960.63
315_G350_E0.5950.63
110_I139_H0.5950.63
90_D192_L0.5950.63
285_R394_A0.5940.63
367_I386_Q0.5920.62
319_V354_D0.5900.62
205_I215_H0.5890.62
93_Y98_S0.5870.62
70_S76_A0.5830.61
85_R99_D0.5830.61
141_A146_Q0.5820.61
57_L60_S0.5810.61
219_A245_S0.5810.61
358_C368_D0.5810.61
130_T201_A0.5810.61
61_Q383_Q0.5810.61
175_L366_R0.5800.61
33_L112_D0.5800.61
107_E117_L0.5800.61
209_A266_S0.5790.61
235_L266_S0.5770.60
50_K60_S0.5760.60
218_L248_L0.5760.60
28_Q32_H0.5750.60
229_A245_S0.5750.60
51_Y59_N0.5750.60
107_E116_G0.5740.60
285_R345_T0.5700.59
266_S291_N0.5650.59
263_G414_I0.5650.59
69_I74_R0.5650.59
350_E353_A0.5640.59
210_N240_T0.5630.59
136_S139_H0.5620.58
113_D121_I0.5620.58
319_V346_K0.5620.58
258_S289_E0.5620.58
74_R79_L0.5610.58
387_Q415_G0.5610.58
291_N318_N0.5610.58
303_T311_A0.5600.58
49_W358_C0.5600.58
290_H350_E0.5600.58
216_I402_R0.5590.58
242_F269_R0.5590.58
153_L364_V0.5580.58
36_L128_H0.5580.58
89_V159_Q0.5570.58
246_F398_T0.5570.58
205_I233_L0.5560.58
214_Q402_R0.5550.57
176_D204_T0.5540.57
205_I226_H0.5540.57
130_T136_S0.5530.57
235_L261_L0.5530.57
36_L40_G0.5520.57
332_N361_G0.5520.57
102_E105_G0.5500.57
313_F346_K0.5500.57
29_A128_H0.5500.57
208_A211_A0.5490.57
314_N334_N0.5490.57
176_D208_A0.5490.57
245_S255_H0.5480.57
210_N237_E0.5470.56
247_L274_A0.5470.56
353_A361_G0.5460.56
106_Y183_A0.5450.56
350_E356_V0.5450.56
281_V301_H0.5440.56
301_H314_N0.5420.56
232_D258_S0.5410.56
62_F65_I0.5400.55
87_V155_M0.5390.55
168_T198_F0.5390.55
368_D371_Q0.5390.55
197_H221_E0.5380.55
392_A397_L0.5380.55
88_F136_S0.5380.55
410_V418_L0.5380.55
201_A229_A0.5370.55
32_H35_Q0.5370.55
354_D357_K0.5370.55
199_T227_H0.5360.55
118_P139_H0.5350.55
63_V72_Q0.5350.55
291_N322_H0.5340.55
313_F356_V0.5340.55
88_F98_S0.5330.54
156_H371_Q0.5330.54
147_R267_T0.5330.54
38_R95_P0.5320.54
123_A232_D0.5320.54
334_N343_V0.5300.54
288_L299_Q0.5290.54
328_G332_N0.5290.54
78_A82_D0.5290.54
334_N364_V0.5280.54
74_R78_A0.5280.54
67_G70_S0.5280.54
130_T200_G0.5280.54
228_F254_R0.5270.54
40_G50_K0.5250.53
358_C389_I0.5250.53
51_Y254_R0.5240.53
227_H253_L0.5240.53
126_F200_G0.5220.53
254_R283_D0.5220.53
326_T407_K0.5220.53
363_T394_A0.5220.53
285_R328_G0.5220.53
285_R332_N0.5210.53
249_G280_E0.5200.53
231_N241_A0.5190.53
56_G59_N0.5180.52
353_A363_T0.5170.52
343_V348_Q0.5170.52
54_L59_N0.5160.52
300_L397_L0.5160.52
284_T345_T0.5160.52
200_G328_G0.5150.52
196_R224_L0.5150.52
29_A137_V0.5140.52
45_K51_Y0.5130.52
86_L405_G0.5130.52
155_M190_V0.5130.52
283_D314_N0.5130.52
113_D117_L0.5130.52
214_Q244_H0.5130.52
297_S317_I0.5120.52
140_I148_P0.5110.51
66_A74_R0.5110.51
322_H325_K0.5110.51
277_V306_S0.5110.51
139_H406_L0.5090.51
80_T86_L0.5080.51
55_E59_N0.5080.51
265_N296_N0.5080.51
273_L300_L0.5080.51
85_R95_P0.5070.51
160_G209_A0.5070.51
38_R113_D0.5070.51
320_A353_A0.5070.51
59_N288_L0.5070.51
319_V355_D0.5070.51
274_A366_R0.5060.51
255_H365_G0.5060.51
68_E72_Q0.5050.51
338_G341_A0.5050.51
285_R301_H0.5040.50
290_H352_Y0.5040.50
257_T301_H0.5040.50
232_D362_A0.5020.50
22_G26_S0.5020.50
189_F217_K0.5020.50
302_K331_T0.5020.50
321_Q353_A0.5000.50
412_A415_G0.5000.50
334_N353_A0.5000.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1vh4A 2 0.9764 100 0.133 Contact Map
4dn7A 2 0.9054 100 0.301 Contact Map
4xfmA 2 0.1702 18.9 0.975 Contact Map
1rq8A 1 0.13 18.5 0.975 Contact Map
1ifyA 1 0.1158 16.5 0.975 Contact Map
3ezqB 1 0.1371 15.4 0.976 Contact Map
1wjiA 1 0.1324 14.8 0.976 Contact Map
4v0qA 2 0.13 13 0.976 Contact Map
3dqqA 2 0.182 12.7 0.976 Contact Map
4edgA 1 0.1891 12.2 0.977 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0117 seconds.