ABDH - ECOLI - GREMLIN Contacts

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ABDH - Gamma-aminobutyraldehyde dehydrogenase

UniProt:	P77674	Sequences: MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAAVRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINILFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVGKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13766
Length:	474 (452)
Sequences:	36482 (21911)
Seq/√Len:	1030.6

ECOLI - ABDH PUUC GABD ALDB BETB FEAB ALDA ASTD SAD EUTE PUTA PAAZ PROA
BACSU - ROCA ROCA2 ALDH4 ALDH1 ALDH5 BETB IOLA ALDY GABD ALDH3 ALDH2 PROA
HALSA - Q9HQZ2 Q9HMJ6 Q9HRB5 Q9HR91
SULSO - KGSDH Q97YT9 GAPN Q97XS9 Q97XA5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
290_K	390_D	4.961	1.00
234_S	238_S	3.565	1.00
290_K	388_P	3.148	1.00
262_E	299_K	3.070	1.00
293_Y	388_P	2.907	1.00
20_P	32_E	2.861	1.00
351_E	361_A	2.800	1.00
49_D	216_K	2.779	1.00
257_D	289_Q	2.725	1.00
369_L	372_D	2.645	1.00
337_E	373_A	2.606	1.00
266_E	303_A	2.606	1.00
183_K	186_E	2.586	1.00
325_L	329_E	2.583	1.00
336_E	340_A	2.488	1.00
297_V	386_V	2.472	1.00
257_D	291_G	2.459	1.00
77_N	80_V	2.411	1.00
412_T	418_A	2.383	1.00
20_P	29_V	2.380	1.00
75_E	109_R	2.331	1.00
189_K	194_A	2.242	1.00
335_V	360_Y	2.198	1.00
49_D	218_R	2.177	1.00
37_S	40_Q	2.166	1.00
78_G	102_P	2.164	1.00
332_G	336_E	2.134	1.00
73_V	190_D	2.127	1.00
79_Q	97_F	2.122	1.00
70_L	188_A	2.109	1.00
403_Q	449_L	2.085	1.00
337_E	341_T	2.050	1.00
392_E	417_R	2.029	1.00
176_I	324_S	2.009	1.00
345_K	367_G	2.006	1.00
213_G	235_H	1.992	1.00
137_D	468_R	1.989	1.00
332_G	352_K	1.984	1.00
209_D	213_G	1.968	1.00
253_V	268_V	1.937	1.00
136_R	462_E	1.935	1.00
80_V	183_K	1.933	1.00
420_R	424_R	1.929	1.00
332_G	360_Y	1.927	1.00
301_G	305_A	1.922	1.00
295_T	299_K	1.920	1.00
322_L	331_V	1.841	1.00
230_E	449_L	1.834	1.00
339_K	346_V	1.834	1.00
347_I	366_A	1.825	1.00
231_H	234_S	1.824	1.00
258_D	417_R	1.812	1.00
73_V	191_I	1.787	1.00
77_N	190_D	1.786	1.00
46_R	216_K	1.781	1.00
42_D	210_P	1.777	1.00
73_V	76_E	1.776	1.00
287_Y	398_W	1.773	1.00
66_C	192_F	1.759	1.00
375_V	387_T	1.747	1.00
29_V	32_E	1.722	1.00
426_Q	448_K	1.708	1.00
42_D	46_R	1.693	1.00
136_R	465_T	1.690	1.00
203_R	206_T	1.683	1.00
84_L	183_K	1.640	1.00
289_Q	389_F	1.634	1.00
345_K	366_A	1.628	1.00
370_Q	398_W	1.627	1.00
394_Q	397_N	1.618	1.00
68_L	109_R	1.617	1.00
301_G	347_I	1.611	1.00
185_A	199_I	1.608	1.00
75_E	105_V	1.603	1.00
93_L	97_F	1.600	1.00
304_V	364_L	1.597	1.00
365_L	374_I	1.594	1.00
73_V	187_L	1.590	1.00
392_E	420_R	1.588	1.00
390_D	394_Q	1.587	1.00
273_Y	304_V	1.572	1.00
293_Y	297_V	1.561	1.00
108_F	160_A	1.557	1.00
287_Y	395_V	1.553	1.00
59_T	62_V	1.552	1.00
298_E	302_A	1.549	1.00
299_K	302_A	1.545	1.00
325_L	358_Y	1.543	1.00
268_V	296_L	1.540	1.00
333_K	373_A	1.532	1.00
69_K	72_D	1.528	1.00
72_D	76_E	1.515	1.00
52_F	56_G	1.508	1.00
18_K	32_E	1.508	1.00
373_A	377_K	1.507	1.00
265_V	299_K	1.505	1.00
168_C	196_V	1.503	1.00
261_I	299_K	1.477	1.00
57_Q	424_R	1.466	1.00
256_F	417_R	1.458	1.00
186_E	190_D	1.458	1.00
78_G	97_F	1.454	1.00
62_V	65_E	1.453	1.00
294_D	388_P	1.443	1.00
28_D	356_N	1.441	1.00
286_I	384_V	1.440	1.00
42_D	214_H	1.439	1.00
83_E	87_R	1.438	1.00
287_Y	389_F	1.436	1.00
267_G	411_W	1.432	1.00
336_E	339_K	1.432	1.00
58_T	62_V	1.432	1.00
303_A	306_T	1.424	1.00
68_L	116_R	1.423	1.00
27_G	356_N	1.423	1.00
268_V	286_I	1.416	1.00
293_Y	366_A	1.413	1.00
108_F	156_A	1.408	1.00
346_V	365_L	1.406	1.00
114_A	117_C	1.404	1.00
135_R	423_A	1.402	1.00
22_Y	29_V	1.398	1.00
394_Q	398_W	1.397	1.00
288_A	296_L	1.390	1.00
71_A	109_R	1.389	1.00
295_T	298_E	1.386	1.00
79_Q	83_E	1.381	1.00
408_S	427_Y	1.380	1.00
308_K	316_S	1.370	1.00
77_N	183_K	1.370	1.00
17_E	35_E	1.352	1.00
257_D	417_R	1.350	1.00
144_S	169_V	1.344	1.00
233_I	452_Y	1.339	1.00
40_Q	43_A	1.338	1.00
83_E	313_D	1.337	1.00
331_V	381_G	1.335	1.00
219_M	244_H	1.326	1.00
334_A	379_V	1.321	1.00
393_E	424_R	1.317	1.00
328_L	332_G	1.309	1.00
72_D	109_R	1.307	1.00
294_D	298_E	1.292	1.00
155_A	171_L	1.292	1.00
389_F	398_W	1.291	1.00
341_T	373_A	1.289	1.00
256_F	389_F	1.286	1.00
23_N	26_T	1.286	1.00
86_S	96_A	1.276	1.00
328_L	360_Y	1.276	1.00
329_E	333_K	1.270	1.00
297_V	301_G	1.270	1.00
325_L	328_L	1.269	1.00
254_I	395_V	1.255	1.00
302_A	305_A	1.249	1.00
256_F	421_V	1.248	1.00
185_A	197_I	1.237	1.00
52_F	168_C	1.236	1.00
328_L	352_K	1.236	1.00
391_N	394_Q	1.233	1.00
292_I	295_T	1.223	1.00
289_Q	391_N	1.220	1.00
209_D	235_H	1.214	1.00
333_K	337_E	1.212	1.00
371_D	376_Q	1.212	1.00
299_K	303_A	1.211	1.00
71_A	75_E	1.210	1.00
305_A	348_T	1.209	1.00
396_V	421_V	1.202	1.00
308_K	318_E	1.201	1.00
46_R	50_A	1.201	1.00
459_Y	462_E	1.197	1.00
289_Q	292_I	1.189	1.00
458_L	462_E	1.186	1.00
133_M	419_H	1.174	1.00
302_A	306_T	1.170	1.00
58_T	66_C	1.166	1.00
136_R	467_V	1.162	1.00
195_G	198_N	1.161	1.00
83_E	93_L	1.156	1.00
45_V	217_V	1.151	1.00
188_A	197_I	1.141	1.00
422_S	470_V	1.141	1.00
370_Q	401_D	1.140	1.00
175_E	203_R	1.139	1.00
86_S	312_P	1.139	1.00
297_V	366_A	1.139	1.00
45_V	216_K	1.138	1.00
300_L	384_V	1.138	1.00
45_V	214_H	1.138	1.00
408_S	430_T	1.138	1.00
182_L	201_F	1.136	1.00
38_A	210_P	1.135	1.00
296_L	300_L	1.126	1.00
209_D	231_H	1.126	1.00
139_L	219_M	1.123	1.00
418_A	432_V	1.121	1.00
81_F	183_K	1.118	1.00
231_H	235_H	1.118	1.00
41_V	207_V	1.116	1.00
69_K	73_V	1.101	1.00
310_G	317_T	1.099	1.00
338_A	365_L	1.097	1.00
47_A	198_N	1.097	1.00
175_E	205_K	1.096	1.00
445_G	454_K	1.096	1.00
341_T	372_D	1.093	1.00
121_L	458_L	1.090	1.00
253_V	283_A	1.087	1.00
19_Q	35_E	1.083	1.00
35_E	206_T	1.083	1.00
233_I	243_T	1.082	1.00
68_L	113_G	1.082	1.00
227_A	231_H	1.081	1.00
376_Q	403_Q	1.080	1.00
228_T	231_H	1.080	1.00
393_E	420_R	1.077	1.00
393_E	397_N	1.069	1.00
454_K	466_V	1.068	1.00
70_L	187_L	1.063	1.00
459_Y	467_V	1.060	1.00
31_L	179_L	1.058	1.00
343_H	365_L	1.058	1.00
23_N	311_A	1.050	1.00
305_A	361_A	1.050	1.00
25_A	312_P	1.046	1.00
144_S	221_S	1.046	1.00
210_P	214_H	1.042	1.00
254_I	421_V	1.042	1.00
159_L	197_I	1.040	1.00
70_L	108_F	1.039	1.00
353_R	361_A	1.033	1.00
297_V	347_I	1.032	1.00
159_L	169_V	1.031	1.00
35_E	203_R	1.026	1.00
328_L	358_Y	1.024	1.00
396_V	424_R	1.022	1.00
70_L	192_F	1.020	1.00
376_Q	401_D	1.019	1.00
230_E	240_I	1.015	1.00
254_I	399_A	1.013	1.00
337_E	340_A	1.013	1.00
143_A	217_V	1.012	1.00
389_F	395_V	1.010	1.00
260_D	413_K	1.004	1.00
301_G	348_T	1.003	1.00
64_A	116_R	1.000	1.00
27_G	358_Y	0.995	1.00
392_E	421_V	0.994	1.00
104_I	156_A	0.994	1.00
150_Y	279_D	0.993	1.00
51_A	168_C	0.993	1.00
141_V	168_C	0.993	1.00
213_G	238_S	0.989	1.00
414_D	417_R	0.985	1.00
260_D	263_A	0.985	1.00
311_A	314_D	0.981	1.00
307_L	319_L	0.977	1.00
250_K	284_C	0.976	1.00
349_G	361_A	0.975	1.00
263_A	267_G	0.973	1.00
175_E	204_G	0.972	1.00
186_E	189_K	0.971	1.00
121_L	459_Y	0.966	1.00
77_N	186_E	0.965	1.00
447_Q	466_V	0.963	1.00
81_F	187_L	0.962	1.00
269_R	303_A	0.958	1.00
115_A	164_A	0.949	1.00
135_R	470_V	0.948	1.00
68_L	112_A	0.945	1.00
80_V	83_E	0.944	1.00
182_L	199_I	0.941	1.00
82_A	97_F	0.940	1.00
409_S	435_H	0.940	1.00
38_A	42_D	0.937	1.00
397_N	401_D	0.937	1.00
271_F	283_A	0.936	1.00
139_L	242_R	0.935	1.00
262_E	295_T	0.935	1.00
143_A	211_L	0.935	1.00
76_E	190_D	0.933	1.00
73_V	77_N	0.932	1.00
368_A	372_D	0.930	1.00
233_I	237_A	0.929	1.00
38_A	206_T	0.926	1.00
77_N	187_L	0.925	1.00
132_S	442_M	0.924	1.00
87_R	313_D	0.921	1.00
333_K	336_E	0.917	1.00
142_V	219_M	0.917	1.00
334_A	337_E	0.917	1.00
349_G	363_T	0.916	1.00
331_V	383_V	0.914	1.00
23_N	87_R	0.913	1.00
104_I	152_L	0.913	1.00
65_E	69_K	0.910	1.00
53_A	397_N	0.909	1.00
218_R	426_Q	0.908	1.00
252_P	408_S	0.904	1.00
272_G	284_C	0.900	1.00
49_D	53_A	0.899	1.00
64_A	68_L	0.898	1.00
89_C	177_T	0.897	1.00
253_V	411_W	0.896	1.00
137_D	423_A	0.890	1.00
176_I	326_A	0.885	1.00
137_D	447_Q	0.884	1.00
261_I	265_V	0.884	1.00
56_G	426_Q	0.884	1.00
43_A	47_A	0.882	1.00
230_E	234_S	0.881	1.00
91_K	100_E	0.880	1.00
22_Y	358_Y	0.878	1.00
141_V	217_V	0.876	1.00
60_P	64_A	0.876	1.00
294_D	297_V	0.875	1.00
53_A	57_Q	0.874	1.00
41_V	143_A	0.874	1.00
233_I	236_T	0.871	1.00
419_H	423_A	0.871	1.00
339_K	365_L	0.871	1.00
57_Q	423_A	0.868	1.00
53_A	426_Q	0.867	1.00
185_A	189_K	0.866	1.00
23_N	28_D	0.866	1.00
331_V	379_V	0.861	1.00
256_F	412_T	0.856	1.00
293_Y	386_V	0.856	1.00
343_H	372_D	0.856	1.00
256_F	392_E	0.854	1.00
25_A	359_Y	0.854	1.00
71_A	112_A	0.853	1.00
442_M	469_H	0.852	1.00
387_T	398_W	0.846	1.00
182_L	186_E	0.846	1.00
408_S	425_L	0.845	1.00
225_S	228_T	0.843	1.00
265_V	300_L	0.843	1.00
265_V	303_A	0.841	1.00
334_A	373_A	0.840	1.00
329_E	332_G	0.840	1.00
220_V	236_T	0.839	1.00
165_A	465_T	0.839	1.00
242_R	466_V	0.834	1.00
74_I	104_I	0.833	1.00
161_P	460_G	0.826	1.00
370_Q	387_T	0.824	1.00
39_E	43_A	0.824	1.00
158_K	455_D	0.821	1.00
64_A	112_A	0.820	1.00
51_A	196_V	0.817	1.00
48_A	198_N	0.814	1.00
171_L	181_A	0.809	1.00
36_A	40_Q	0.809	1.00
139_L	466_V	0.808	1.00
162_A	169_V	0.806	1.00
233_I	240_I	0.806	1.00
43_A	46_R	0.806	1.00
19_Q	203_R	0.806	1.00
47_A	195_G	0.804	1.00
395_V	398_W	0.803	1.00
298_E	301_G	0.802	1.00
53_A	56_G	0.802	1.00
173_P	201_F	0.796	1.00
410_V	421_V	0.796	1.00
55_W	196_V	0.794	1.00
265_V	296_L	0.793	1.00
68_L	72_D	0.793	1.00
39_E	42_D	0.792	1.00
415_V	418_A	0.792	1.00
396_V	400_N	0.791	1.00
66_C	191_I	0.789	1.00
229_G	247_L	0.787	1.00
264_V	268_V	0.786	1.00
94_H	318_E	0.782	1.00
255_V	296_L	0.781	1.00
326_A	329_E	0.781	1.00
220_V	232_I	0.778	1.00
139_L	167_N	0.777	1.00
156_A	184_L	0.775	1.00
61_K	116_R	0.774	1.00
89_C	323_S	0.773	1.00
427_Y	430_T	0.772	1.00
75_E	78_G	0.772	1.00
230_E	238_S	0.770	1.00
30_L	87_R	0.769	1.00
366_A	388_P	0.769	1.00
205_K	209_D	0.768	1.00
155_A	159_L	0.766	1.00
335_V	383_V	0.766	1.00
87_R	179_L	0.764	1.00
309_S	353_R	0.764	1.00
389_F	394_Q	0.764	1.00
261_I	292_I	0.759	1.00
86_S	93_L	0.756	1.00
202_G	207_V	0.755	1.00
331_V	360_Y	0.754	1.00
226_I	449_L	0.753	1.00
229_G	245_M	0.753	1.00
50_A	53_A	0.752	1.00
144_S	158_K	0.750	1.00
289_Q	392_E	0.745	1.00
69_K	191_I	0.745	1.00
251_A	284_C	0.745	1.00
307_L	318_E	0.744	1.00
222_L	228_T	0.744	1.00
300_L	364_L	0.742	1.00
212_T	232_I	0.742	1.00
206_T	209_D	0.741	1.00
293_Y	367_G	0.740	1.00
252_P	399_A	0.740	1.00
350_G	363_T	0.739	1.00
207_V	210_P	0.739	1.00
152_L	180_T	0.739	1.00
36_A	44_A	0.738	1.00
334_A	377_K	0.736	1.00
67_L	164_A	0.735	1.00
262_E	303_A	0.734	1.00
82_A	93_L	0.733	1.00
236_T	243_T	0.732	1.00
50_A	54_E	0.732	1.00
93_L	313_D	0.730	1.00
339_K	351_E	0.729	1.00
132_S	469_H	0.727	1.00
413_K	416_G	0.725	1.00
155_A	181_A	0.725	1.00
208_G	212_T	0.722	1.00
48_A	168_C	0.716	1.00
75_E	102_P	0.716	1.00
79_Q	93_L	0.714	1.00
82_A	86_S	0.712	1.00
97_F	315_E	0.709	1.00
55_W	66_C	0.705	1.00
54_E	58_T	0.705	1.00
22_Y	27_G	0.703	1.00
139_L	218_R	0.702	1.00
212_T	235_H	0.702	1.00
143_A	220_V	0.700	1.00
176_I	323_S	0.700	1.00
80_V	186_E	0.697	1.00
146_A	155_A	0.695	1.00
314_D	317_T	0.695	1.00
264_V	296_L	0.694	1.00
265_V	269_R	0.694	1.00
330_R	333_K	0.693	1.00
171_L	197_I	0.691	1.00
288_A	292_I	0.690	1.00
324_S	327_H	0.690	1.00
42_D	216_K	0.689	1.00
17_E	206_T	0.686	1.00
235_H	238_S	0.685	1.00
301_G	304_V	0.685	1.00
234_S	237_A	0.682	1.00
72_D	75_E	0.680	1.00
18_K	34_A	0.678	1.00
27_G	325_L	0.677	1.00
49_D	52_F	0.676	1.00
304_V	348_T	0.675	1.00
192_F	197_I	0.673	1.00
256_F	289_Q	0.671	1.00
415_V	419_H	0.668	1.00
84_L	179_L	0.668	1.00
60_P	115_A	0.668	1.00
155_A	184_L	0.667	1.00
276_A	319_L	0.664	1.00
304_V	307_L	0.664	1.00
74_I	105_V	0.664	1.00
360_Y	363_T	0.662	1.00
309_S	319_L	0.661	1.00
167_N	465_T	0.661	1.00
327_H	330_R	0.660	1.00
342_G	372_D	0.660	1.00
258_D	412_T	0.660	1.00
242_R	463_D	0.660	1.00
55_W	163_L	0.659	1.00
143_A	208_G	0.658	1.00
287_Y	375_V	0.657	1.00
56_G	424_R	0.656	1.00
462_E	467_V	0.656	1.00
255_V	264_V	0.655	1.00
462_E	465_T	0.654	1.00
286_I	296_L	0.654	1.00
23_N	313_D	0.654	1.00
341_T	371_D	0.654	1.00
85_E	88_N	0.654	1.00
135_R	468_R	0.653	1.00
188_A	192_F	0.653	1.00
212_T	220_V	0.653	1.00
62_V	66_C	0.653	1.00
54_E	57_Q	0.651	1.00
370_Q	375_V	0.650	1.00
422_S	432_V	0.649	1.00
426_Q	447_Q	0.649	1.00
269_R	300_L	0.649	1.00
78_G	82_A	0.648	1.00
261_I	295_T	0.648	1.00
418_A	422_S	0.647	1.00
269_R	307_L	0.645	1.00
398_W	401_D	0.643	1.00
268_V	300_L	0.643	1.00
41_V	210_P	0.643	1.00
287_Y	370_Q	0.642	1.00
131_T	419_H	0.640	1.00
263_A	266_E	0.640	1.00
204_G	208_G	0.639	1.00
41_V	45_V	0.638	1.00
325_L	352_K	0.636	1.00
244_H	463_D	0.633	1.00
53_A	424_R	0.631	1.00
311_A	317_T	0.629	1.00
263_A	413_K	0.629	1.00
326_A	330_R	0.628	1.00
56_G	138_P	0.627	1.00
74_I	108_F	0.627	1.00
47_A	194_A	0.625	1.00
91_K	150_Y	0.624	1.00
158_K	221_S	0.623	1.00
328_L	353_R	0.622	1.00
118_L	465_T	0.622	1.00
71_A	105_V	0.622	1.00
38_A	213_G	0.619	1.00
338_A	379_V	0.619	1.00
51_A	54_E	0.618	1.00
392_E	396_V	0.617	1.00
233_I	245_M	0.616	1.00
175_E	330_R	0.615	1.00
91_K	95_S	0.614	1.00
368_A	374_I	0.613	1.00
34_A	201_F	0.612	1.00
21_V	31_L	0.610	1.00
368_A	375_V	0.609	1.00
83_E	86_S	0.609	1.00
258_D	414_D	0.608	1.00
391_N	397_N	0.607	1.00
101_I	105_V	0.606	1.00
335_V	365_L	0.606	1.00
258_D	413_K	0.606	1.00
85_E	180_T	0.605	1.00
56_G	137_D	0.604	1.00
412_T	417_R	0.603	1.00
44_A	200_L	0.602	1.00
183_K	187_L	0.602	1.00
416_G	419_H	0.601	1.00
21_V	88_N	0.601	1.00
175_E	231_H	0.601	1.00
118_L	461_L	0.601	1.00
85_E	96_A	0.600	1.00
300_L	386_V	0.596	1.00
159_L	171_L	0.596	1.00
85_E	100_E	0.596	1.00
30_L	179_L	0.595	1.00
262_E	302_A	0.594	1.00
322_L	327_H	0.593	1.00
202_G	208_G	0.593	1.00
332_G	339_K	0.591	1.00
271_F	435_H	0.591	1.00
46_R	49_D	0.591	1.00
81_F	152_L	0.590	1.00
60_P	164_A	0.589	1.00
38_A	209_D	0.589	1.00
86_S	313_D	0.589	1.00
346_V	363_T	0.587	1.00
379_V	383_V	0.587	1.00
110_F	114_A	0.585	1.00
370_Q	397_N	0.585	1.00
395_V	399_A	0.584	1.00
410_V	418_A	0.584	1.00
205_K	231_H	0.583	1.00
350_G	361_A	0.582	1.00
335_V	363_T	0.582	1.00
396_V	420_R	0.582	1.00
74_I	184_L	0.581	1.00
170_V	198_N	0.580	1.00
334_A	338_A	0.580	1.00
261_I	264_V	0.579	1.00
152_L	184_L	0.579	1.00
253_V	286_I	0.578	1.00
226_I	230_E	0.578	1.00
82_A	101_I	0.577	1.00
142_V	167_N	0.577	1.00
33_I	178_P	0.575	1.00
272_G	384_V	0.575	1.00
261_I	296_L	0.575	1.00
367_G	388_P	0.575	1.00
332_G	335_V	0.574	1.00
288_A	386_V	0.571	1.00
416_G	420_R	0.571	1.00
288_A	293_Y	0.570	1.00
36_A	200_L	0.570	1.00
74_I	152_L	0.569	1.00
253_V	409_S	0.567	1.00
410_V	432_V	0.566	1.00
219_M	463_D	0.565	1.00
133_M	470_V	0.564	1.00
352_K	361_A	0.563	1.00
365_L	368_A	0.561	1.00
141_V	218_R	0.560	1.00
165_A	461_L	0.559	1.00
44_A	198_N	0.558	1.00
71_A	108_F	0.558	1.00
65_E	68_L	0.553	1.00
114_A	458_L	0.552	1.00
392_E	424_R	0.551	1.00
113_G	116_R	0.551	1.00
279_D	282_A	0.551	1.00
137_D	426_Q	0.550	1.00
70_L	73_V	0.549	1.00
17_E	37_S	0.549	1.00
61_K	65_E	0.548	1.00
341_T	369_L	0.548	1.00
426_Q	466_V	0.547	1.00
308_K	314_D	0.547	1.00
286_I	386_V	0.547	1.00
97_F	102_P	0.545	1.00
49_D	141_V	0.541	1.00
348_T	364_L	0.541	1.00
101_I	152_L	0.540	1.00
431_W	434_T	0.540	1.00
47_A	51_A	0.540	1.00
168_C	198_N	0.540	1.00
396_V	425_L	0.540	1.00
243_T	452_Y	0.539	1.00
102_P	105_V	0.538	1.00
111_F	161_P	0.537	1.00
374_I	379_V	0.536	1.00
184_L	188_A	0.536	1.00
257_D	389_F	0.536	1.00
251_A	407_A	0.535	1.00
163_L	192_F	0.535	1.00
322_L	360_Y	0.535	1.00
163_L	197_I	0.535	1.00
48_A	170_V	0.534	1.00
209_D	212_T	0.534	1.00
66_C	70_L	0.534	1.00
157_W	456_M	0.533	1.00
399_A	425_L	0.533	1.00
189_K	195_G	0.532	1.00
89_C	275_N	0.530	1.00
301_G	364_L	0.530	1.00
283_A	409_S	0.530	1.00
227_A	326_A	0.528	1.00
259_A	264_V	0.524	1.00
142_V	169_V	0.524	1.00
153_M	157_W	0.524	1.00
421_V	425_L	0.524	1.00
21_V	178_P	0.523	1.00
290_K	293_Y	0.523	1.00
78_G	105_V	0.523	1.00
266_E	270_T	0.522	1.00
103_A	153_M	0.521	1.00
48_A	141_V	0.520	1.00
212_T	239_S	0.520	1.00
130_H	434_T	0.518	1.00
221_S	464_Y	0.514	1.00
33_I	179_L	0.513	1.00
346_V	350_G	0.513	1.00
430_T	468_R	0.511	1.00
330_R	334_A	0.511	1.00
265_V	292_I	0.511	1.00
144_S	159_L	0.509	1.00
44_A	170_V	0.508	1.00
309_S	318_E	0.508	1.00
347_I	367_G	0.508	1.00
92_P	317_T	0.507	1.00
300_L	304_V	0.505	1.00
447_Q	454_K	0.504	1.00
107_V	456_M	0.504	1.00
327_H	331_V	0.503	1.00
407_A	431_W	0.502	1.00
81_F	101_I	0.501	1.00
47_A	50_A	0.501	1.00
175_E	227_A	0.501	1.00
226_I	403_Q	0.501	1.00
82_A	96_A	0.501	1.00
74_I	81_F	0.501	1.00
100_E	150_Y	0.500	1.00
346_V	349_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1wndA	4	1	100	0.008	Contact Map
4o5hA	4	0.9979	100	0.013	Contact Map
3ek1A	5	0.9916	100	0.015	Contact Map
4qf6A	4	0.9958	100	0.017	Contact Map
4pxlA	4	0.9958	100	0.017	Contact Map
4yweA	5	0.9873	100	0.017	Contact Map
1a4sA	4	0.9916	100	0.018	Contact Map
4qtoA	4	0.9958	100	0.021	Contact Map
4pz2A	4	0.9958	100	0.022	Contact Map
4f3xA	4	0.9958	100	0.022	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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