GREMLIN Database
SUFA - Protein SufA
UniProt: P77667 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11378
Length: 122 (105)
Sequences: 3691 (1875)
Seq/√Len: 182.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
91_E106_H4.4781.00
27_H30_E3.5891.00
40_G78_F3.0791.00
25_A73_D3.0161.00
80_P83_A2.9641.00
44_G56_V2.7881.00
19_T91_E2.7061.00
110_A113_E2.6211.00
22_P73_D2.4381.00
71_E76_K2.4081.00
69_L76_K2.3401.00
18_L92_V2.2691.00
46_K56_V2.1541.00
37_G61_S2.1451.00
42_R67_D2.1291.00
63_P78_F2.0701.00
21_T93_D1.9561.00
90_T105_F1.8151.00
96_R101_Q1.6971.00
71_E74_G1.6561.00
29_R74_G1.6491.00
29_R33_A1.5471.00
40_G76_K1.4841.00
53_F86_F1.4031.00
63_P69_L1.3451.00
22_P72_H1.3241.00
48_T98_G1.3181.00
60_V64_D1.3161.00
23_A93_D1.3131.00
95_V104_K1.2061.00
22_P26_I1.2031.00
26_I29_R1.1841.00
43_L87_I1.1791.00
28_I41_V1.1731.00
68_L81_L1.1591.00
20_L28_I1.1341.00
112_N121_G1.1271.00
85_P88_D1.1191.00
60_V63_P1.1061.00
35_Q39_V1.0811.00
27_H103_F1.0811.00
17_G88_D1.0711.00
90_T118_E1.0381.00
82_Q85_P1.0381.00
32_V38_M1.0381.00
97_E104_K1.0160.99
25_A75_A1.0130.99
47_Q51_A0.9260.99
81_L85_P0.9230.99
89_G108_P0.9220.99
27_H31_L0.9150.99
70_F84_M0.9120.99
23_A26_I0.9090.99
95_V100_N0.9070.99
63_P76_K0.9000.99
24_A115_G0.8970.99
33_A36_P0.8890.99
97_E102_I0.8590.98
51_A121_G0.8590.98
39_V63_P0.8580.98
43_L92_V0.8390.98
83_A92_V0.8340.98
48_T54_G0.8290.98
25_A72_H0.8280.98
20_L77_L0.8270.98
26_I73_D0.8220.98
41_V103_F0.8170.98
111_Q121_G0.8150.98
35_Q61_S0.7870.97
20_L103_F0.7810.97
48_T110_A0.7780.97
27_H94_F0.7750.97
29_R73_D0.7700.97
27_H99_L0.7680.96
87_I109_K0.7600.96
29_R75_A0.7580.96
97_E100_N0.7540.96
40_G63_P0.7500.96
84_M88_D0.7440.96
32_V39_V0.7400.96
20_L25_A0.7380.96
28_I75_A0.7330.95
95_V102_I0.7290.95
89_G109_K0.7280.95
17_G84_M0.7190.95
32_V40_G0.7130.95
51_A120_F0.7110.95
24_A100_N0.7090.95
53_F57_L0.7070.94
44_G58_D0.7050.94
97_E101_Q0.6970.94
20_L72_H0.6960.94
32_V59_S0.6950.94
47_Q53_F0.6920.94
116_C119_S0.6880.94
25_A74_G0.6850.93
31_L103_F0.6840.93
51_A112_N0.6800.93
57_L86_F0.6750.93
45_V120_F0.6710.93
26_I33_A0.6680.93
42_R60_V0.6670.93
64_D67_D0.6630.92
107_N110_A0.6630.92
28_I103_F0.6550.92
53_F120_F0.6470.91
39_V61_S0.6450.91
18_L89_G0.6350.91
24_A111_Q0.6350.91
45_V48_T0.6330.91
68_L88_D0.6290.90
68_L84_M0.6290.90
38_M59_S0.6260.90
69_L78_F0.6260.90
72_H77_L0.6170.89
96_R115_G0.6130.89
27_H96_R0.6110.89
33_A64_D0.6090.89
117_G120_F0.6040.88
33_A37_G0.6010.88
60_V67_D0.5980.88
95_V99_L0.5930.87
22_P25_A0.5920.87
40_G69_L0.5880.87
110_A120_F0.5880.87
66_D81_L0.5880.87
94_F101_Q0.5810.86
28_I32_V0.5810.86
18_L90_T0.5800.86
34_K39_V0.5790.86
48_T51_A0.5750.86
20_L92_V0.5640.85
51_A86_F0.5640.85
47_Q82_Q0.5610.84
105_F118_E0.5580.84
64_D81_L0.5530.84
114_C119_S0.5510.83
38_M61_S0.5500.83
18_L102_I0.5490.83
84_M104_K0.5480.83
54_G105_F0.5450.83
116_C120_F0.5450.83
35_Q38_M0.5440.83
31_L59_S0.5310.81
29_R32_V0.5290.81
36_P61_S0.5290.81
88_D109_K0.5270.81
68_L85_P0.5260.80
47_Q57_L0.5250.80
82_Q86_F0.5230.80
17_G72_H0.5210.80
57_L100_N0.5160.79
75_A90_T0.5100.78
21_T99_L0.5070.78
53_F115_G0.5050.78
57_L90_T0.5050.78
65_K81_L0.5040.78
25_A29_R0.5000.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2d2aA 2 0.9672 100 0.144 Contact Map
1nwbA 1 0.8197 100 0.194 Contact Map
1r94A 3 0.7951 100 0.195 Contact Map
1x0gA 4 0.8689 100 0.199 Contact Map
2apnA 1 0.9262 100 0.21 Contact Map
2k4zA 1 0.9672 100 0.364 Contact Map
2p2eA 1 0.8443 99.9 0.483 Contact Map
2qgoA 1 0.7377 99.8 0.5 Contact Map
2qrjA 1 0.9016 21.5 0.928 Contact Map
5aunA 1 0.623 15.1 0.932 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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