GREMLIN Database
YQIH - Uncharacterized fimbrial chaperone YqiH
UniProt: P77616 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14229
Length: 249 (215)
Sequences: 2829 (2145)
Seq/√Len: 146.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
62_I137_L3.2131.00
178_T197_M3.1851.00
176_H199_T2.9901.00
170_N203_Y2.9631.00
109_L197_M2.9181.00
37_N40_D2.8751.00
199_T202_S2.8731.00
29_P135_L2.8391.00
106_R201_F2.7961.00
168_R205_N2.5601.00
102_L110_F2.5491.00
34_I43_E2.4991.00
56_Y116_E2.4281.00
168_R203_Y2.4211.00
138_F197_M2.3831.00
34_I112_F2.3741.00
221_N227_S2.3661.00
34_I93_M2.3611.00
39_S142_K2.2901.00
169_F206_T2.2181.00
158_E170_N2.1731.00
162_R168_R2.1091.00
138_F176_H2.0991.00
55_P84_N2.0831.00
63_E134_A2.0591.00
155_E159_I2.0461.00
61_W113_N2.0021.00
160_I168_R1.9071.00
115_R132_Q1.8981.00
37_N43_E1.8551.00
60_T91_I1.8251.00
74_I93_M1.8091.00
166_S205_N1.7961.00
84_N87_E1.7721.00
103_P108_T1.7451.00
144_I175_Y1.7311.00
154_Y157_V1.7141.00
29_P114_V1.7021.00
154_Y159_I1.6881.00
109_L138_F1.6831.00
55_P82_R1.6731.00
159_I169_F1.6621.00
177_V219_Y1.6411.00
76_T91_I1.6161.00
63_E113_N1.6121.00
113_N134_A1.5921.00
147_E150_G1.5211.00
62_I72_D1.5151.00
64_D68_N1.5091.00
153_T177_V1.4861.00
181_Y218_G1.4351.00
153_T219_Y1.4231.00
146_L150_G1.4101.00
42_G92_R1.4081.00
58_A81_V1.3961.00
95_T100_A1.3751.00
36_M43_E1.3691.00
198_V204_A1.3691.00
157_V169_F1.3661.00
221_N225_G1.3571.00
74_I137_L1.3511.00
38_E104_K1.3431.00
109_L178_T1.3171.00
45_L112_F1.3151.00
46_K88_Q1.2871.00
157_V160_I1.2731.00
34_I135_L1.2631.00
103_P106_R1.2601.00
51_S116_E1.2581.00
162_R166_S1.2461.00
53_N86_S1.2341.00
47_L83_L1.2041.00
29_P45_L1.1761.00
38_E142_K1.1741.00
162_R205_N1.1701.00
95_T139_W1.1691.00
167_I208_F1.1661.00
157_V161_R1.1651.00
185_N189_M1.1631.00
183_G216_Q1.1621.00
174_P201_F1.1551.00
121_T128_Q1.1531.00
178_T219_Y1.1471.00
150_G155_E1.1441.00
180_G226_L1.1420.99
121_T126_V1.1420.99
166_S207_Q1.1360.99
91_I112_F1.1360.99
95_T101_Q1.1300.99
112_F137_L1.1260.99
93_M137_L1.1250.99
28_I31_R1.1190.99
179_L198_V1.1120.99
219_Y227_S1.0950.99
31_R45_L1.0920.99
64_D70_S1.0840.99
155_E161_R1.0840.99
157_V177_V1.0820.99
157_V179_L1.0760.99
61_W134_A1.0700.99
76_T93_M1.0620.99
15_L20_S1.0590.99
160_I170_N1.0550.99
48_T88_Q1.0520.99
26_A116_E1.0490.99
63_E67_G1.0400.99
154_Y177_V1.0390.99
38_E139_W1.0340.99
111_Y134_A1.0260.99
146_L175_Y1.0150.99
30_D46_K1.0080.99
116_E131_M1.0000.99
186_G189_M0.9860.99
36_M94_I0.9780.98
27_I83_L0.9740.98
156_K172_K0.9730.98
219_Y229_Y0.9630.98
20_S24_W0.9600.98
13_G16_L0.9590.98
176_H200_P0.9510.98
33_R140_R0.9470.98
29_P47_L0.9470.98
81_V89_I0.9430.98
76_T112_F0.9390.98
61_W115_R0.9350.98
159_I217_V0.9330.98
12_A15_L0.9300.98
11_A14_V0.9240.98
156_K173_M0.9210.98
170_N201_F0.9190.98
27_I58_A0.9190.98
36_M74_I0.9140.98
136_K220_I0.9050.97
51_S54_L0.9010.97
14_V17_S0.8810.97
179_L219_Y0.8740.97
91_I114_V0.8620.97
51_S56_Y0.8620.97
102_L106_R0.8610.96
105_D201_F0.8600.96
218_G226_L0.8560.96
153_T157_V0.8450.96
154_Y173_M0.8380.96
36_M95_T0.8360.96
60_T76_T0.8330.96
83_L88_Q0.8310.96
30_D88_Q0.8310.96
183_G187_V0.8300.96
62_I76_T0.8230.95
159_I182_I0.8220.95
63_E111_Y0.8120.95
89_I115_R0.8110.95
97_E100_A0.7930.94
183_G188_T0.7930.94
154_Y217_V0.7920.94
218_G228_F0.7920.94
26_A56_Y0.7870.94
154_Y219_Y0.7870.94
184_T215_F0.7840.94
109_L176_H0.7830.94
111_Y115_R0.7760.94
21_S24_W0.7710.94
130_T159_I0.7710.94
105_D140_R0.7640.93
89_I116_E0.7600.93
34_I45_L0.7600.93
110_F139_W0.7550.93
33_R136_K0.7550.93
113_N132_Q0.7540.93
58_A83_L0.7530.93
28_I50_Q0.7520.93
60_T114_V0.7490.93
162_R207_Q0.7460.92
81_V91_I0.7460.92
108_T139_W0.7450.92
161_R164_D0.7440.92
59_Q115_R0.7410.92
107_E140_R0.7380.92
83_L89_I0.7310.92
179_L225_G0.7270.91
9_I17_S0.7240.91
19_M24_W0.7230.91
114_V135_L0.7220.91
62_I117_I0.7200.91
150_G156_K0.7190.91
178_T195_S0.7160.91
47_L58_A0.7150.91
35_I140_R0.7150.91
143_A146_L0.7090.90
111_Y136_K0.7050.90
50_Q119_P0.6960.90
10_I13_G0.6960.90
136_K140_R0.6950.90
167_I182_I0.6930.89
93_M112_F0.6920.89
65_T111_Y0.6900.89
19_M23_A0.6880.89
21_S228_F0.6880.89
14_V21_S0.6850.89
113_N136_K0.6820.89
74_I108_T0.6810.89
162_R165_G0.6780.88
161_R165_G0.6760.88
104_K143_A0.6750.88
46_K80_M0.6750.88
67_G134_A0.6750.88
27_I56_Y0.6740.88
26_A50_Q0.6730.88
83_L87_E0.6670.88
80_M88_Q0.6660.87
182_I206_T0.6650.87
9_I16_L0.6640.87
31_R34_I0.6620.87
33_R222_D0.6610.87
56_Y115_R0.6600.87
56_Y60_T0.6590.87
161_R211_V0.6590.87
29_P50_Q0.6570.87
180_G220_I0.6550.87
65_T109_L0.6550.87
55_P119_P0.6540.87
185_N214_T0.6530.86
97_E101_Q0.6520.86
94_I200_P0.6500.86
136_K178_T0.6470.86
102_L108_T0.6440.86
28_I133_H0.6430.86
75_V94_I0.6420.86
106_R141_P0.6410.85
195_S206_T0.6400.85
167_I215_F0.6390.85
37_N138_F0.6320.85
179_L217_V0.6270.84
111_Y178_T0.6230.84
194_Q207_Q0.6200.84
9_I12_A0.6180.83
220_I227_S0.6180.83
105_D108_T0.6140.83
32_T140_R0.6090.82
181_Y185_N0.6080.82
57_L175_Y0.6040.82
183_G186_G0.6030.82
20_S23_A0.6010.82
127_M134_A0.5980.81
64_D71_R0.5980.81
33_R141_P0.5970.81
116_E130_T0.5960.81
40_D210_N0.5890.80
64_D72_D0.5880.80
14_V20_S0.5860.80
66_K69_K0.5810.79
21_S86_S0.5800.79
198_V202_S0.5780.79
74_I139_W0.5780.79
102_L105_D0.5760.79
56_Y83_L0.5760.79
169_F179_L0.5730.78
60_T89_I0.5720.78
79_P117_I0.5700.78
61_W133_H0.5690.78
182_I208_F0.5680.78
57_L115_R0.5670.78
111_Y114_V0.5670.78
59_Q92_R0.5660.78
116_E178_T0.5650.77
92_R118_P0.5630.77
62_I110_F0.5610.77
16_L209_K0.5590.77
51_S115_R0.5590.77
65_T134_A0.5570.76
167_I205_N0.5560.76
196_L206_T0.5530.76
153_T159_I0.5520.76
40_D100_A0.5520.76
116_E132_Q0.5480.75
118_P130_T0.5440.75
29_P133_H0.5430.75
169_F198_V0.5430.75
57_L79_P0.5400.74
131_M195_S0.5390.74
77_V92_R0.5380.74
16_L20_S0.5370.74
140_R200_P0.5370.74
47_L119_P0.5360.74
29_P57_L0.5350.74
79_P94_I0.5340.73
21_S203_Y0.5330.73
130_T134_A0.5330.73
13_G214_T0.5320.73
155_E160_I0.5320.73
209_K216_Q0.5310.73
44_A55_P0.5300.73
20_S25_G0.5290.73
83_L191_P0.5280.73
167_I184_T0.5250.72
207_Q211_V0.5240.72
204_A207_Q0.5220.72
15_L19_M0.5220.72
182_I209_K0.5210.72
101_Q104_K0.5210.72
44_A129_V0.5200.72
35_I136_K0.5200.72
60_T81_V0.5200.72
55_P85_P0.5170.71
72_D77_V0.5160.71
70_S120_K0.5160.71
11_A18_C0.5150.71
104_K142_K0.5130.71
14_V22_I0.5120.70
67_G70_S0.5120.70
125_N128_Q0.5110.70
46_K115_R0.5100.70
105_D141_P0.5100.70
57_L82_R0.5090.70
69_K125_N0.5080.70
183_G218_G0.5070.70
61_W111_Y0.5070.70
13_G24_W0.5070.70
11_A75_V0.5060.69
54_L119_P0.5050.69
131_M134_A0.5040.69
73_F108_T0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2xg5A 1 0.8514 100 0.206 Contact Map
3q48A 1 0.759 100 0.217 Contact Map
3gfuC 1 0.8273 100 0.219 Contact Map
2co7B 1 0.7831 100 0.221 Contact Map
1klfA 1 0.7992 100 0.232 Contact Map
1l4iA 2 0.759 100 0.236 Contact Map
4ay0A 2 0.755 100 0.264 Contact Map
4djmA 1 0.7992 100 0.266 Contact Map
4ncdA 2 0.7751 100 0.298 Contact Map
2qsvA 1 0.7831 90.6 0.921 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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