ANSP - ECOLI - GREMLIN Contacts

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ANSP - L-asparagine permease

UniProt:	P77610	Sequences: MSKHDTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNMIGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVMLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMAMGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIIVCQMRLRKAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQEIVFKPETAS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13776
Length:	499 (430)
Sequences:	24744 (15998)
Seq/√Len:	771.5

ECOLI - ANSP LYSP PROY AROP YIFK PHEP GABP PUUP CYCA MMUP GADC FRLA PLAP POTE ADIC YGJI ARCD YJEM YBAT YCAM CADB YJEH
BACSU - YBXG YDGF GABP YTNA ROCC YBGF AAPA HUTM YVBW ASPP YHDG YBEC ROCE YFNA STET YCGH ARCD YECA YDAO GERBB GERAB YNDE GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97Z63 Q97WS3 Q97X49 Q97XM0 Q97U05 Q97ZB5 Q7LXI7 Q97VA6 Q97U33 Q97WD4 Q97VA8 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
156_G	360_L	4.590	1.00
342_F	354_A	4.500	1.00
402_R	406_A	3.595	1.00
345_K	354_A	3.246	1.00
394_A	430_L	3.231	1.00
71_G	265_G	3.078	1.00
248_D	251_T	3.002	1.00
251_T	255_K	2.884	1.00
31_G	247_K	2.840	1.00
334_A	344_A	2.742	1.00
342_F	345_K	2.709	1.00
347_S	353_Y	2.688	1.00
246_C	252_M	2.584	1.00
36_Q	259_S	2.466	1.00
149_L	364_V	2.464	1.00
32_N	259_S	2.457	1.00
111_G	333_M	2.417	1.00
293_T	296_S	2.319	1.00
95_V	336_G	2.318	1.00
397_I	429_T	2.286	1.00
157_T	161_I	2.284	1.00
188_G	274_L	2.273	1.00
160_M	353_Y	2.261	1.00
331_R	335_M	2.221	1.00
460_L	464_G	2.144	1.00
153_T	364_V	2.139	1.00
458_G	461_L	2.133	1.00
357_L	361_V	2.120	1.00
186_V	190_V	2.104	1.00
35_V	246_C	2.087	1.00
175_L	179_L	2.074	1.00
156_G	356_I	2.073	1.00
293_T	297_K	2.040	1.00
32_N	252_M	2.039	1.00
302_Y	306_I	2.036	1.00
255_K	259_S	2.008	1.00
164_K	168_E	2.002	1.00
99_R	107_A	1.994	1.00
99_R	104_E	1.982	1.00
343_M	358_A	1.976	1.00
32_N	36_Q	1.953	1.00
149_L	367_V	1.940	1.00
462_V	466_F	1.932	1.00
153_T	360_L	1.914	1.00
245_E	328_R	1.902	1.00
55_R	63_L	1.895	1.00
148_A	367_V	1.886	1.00
244_G	335_M	1.877	1.00
102_L	398_V	1.873	1.00
458_G	462_V	1.870	1.00
398_V	430_L	1.859	1.00
80_A	397_I	1.856	1.00
31_G	34_Q	1.850	1.00
73_F	432_F	1.834	1.00
115_F	359_T	1.828	1.00
34_Q	171_F	1.828	1.00
424_F	428_L	1.828	1.00
427_W	431_L	1.817	1.00
83_E	404_R	1.816	1.00
431_L	435_S	1.815	1.00
337_G	341_S	1.792	1.00
248_D	252_M	1.787	1.00
102_L	402_R	1.781	1.00
26_Y	346_M	1.779	1.00
98_A	110_A	1.773	1.00
452_A	455_P	1.752	1.00
72_L	76_F	1.740	1.00
448_T	451_I	1.709	1.00
143_P	146_V	1.697	1.00
122_G	363_Y	1.688	1.00
36_Q	263_R	1.677	1.00
402_R	405_K	1.673	1.00
296_S	304_G	1.660	1.00
450_T	453_A	1.656	1.00
66_V	225_L	1.653	1.00
103_G	106_A	1.652	1.00
160_M	357_L	1.632	1.00
110_A	395_F	1.630	1.00
341_S	344_A	1.620	1.00
258_N	262_W	1.615	1.00
152_L	363_Y	1.614	1.00
72_L	428_L	1.566	1.00
126_I	319_L	1.565	1.00
179_L	183_T	1.565	1.00
88_R	100_E	1.558	1.00
454_L	458_G	1.553	1.00
102_L	106_A	1.543	1.00
452_A	456_I	1.539	1.00
345_K	353_Y	1.526	1.00
435_S	439_L	1.521	1.00
451_I	454_L	1.515	1.00
129_V	151_A	1.515	1.00
156_G	357_L	1.513	1.00
326_T	359_T	1.502	1.00
463_I	467_G	1.500	1.00
349_Q	353_Y	1.498	1.00
347_S	351_V	1.496	1.00
204_G	207_L	1.475	1.00
76_F	428_L	1.471	1.00
39_A	260_V	1.466	1.00
30_M	34_Q	1.463	1.00
161_I	349_Q	1.459	1.00
449_Y	452_A	1.456	1.00
180_A	310_V	1.454	1.00
149_L	153_T	1.453	1.00
185_L	270_G	1.439	1.00
70_C	229_V	1.433	1.00
133_M	147_F	1.431	1.00
189_T	274_L	1.431	1.00
32_N	255_K	1.430	1.00
98_A	395_F	1.420	1.00
262_W	266_L	1.415	1.00
27_H	350_H	1.405	1.00
330_L	355_G	1.404	1.00
252_M	255_K	1.400	1.00
331_R	346_M	1.399	1.00
401_M	427_W	1.397	1.00
449_Y	453_A	1.396	1.00
464_G	468_V	1.393	1.00
354_A	358_A	1.391	1.00
152_L	360_L	1.388	1.00
289_S	293_T	1.387	1.00
461_L	464_G	1.382	1.00
126_I	152_L	1.376	1.00
34_Q	167_A	1.373	1.00
398_V	402_R	1.371	1.00
159_N	320_N	1.348	1.00
451_I	455_P	1.340	1.00
101_F	399_C	1.335	1.00
457_I	460_L	1.332	1.00
305_S	309_I	1.330	1.00
405_K	423_P	1.323	1.00
296_S	301_P	1.320	1.00
64_A	273_V	1.315	1.00
155_V	319_L	1.314	1.00
242_A	324_Y	1.314	1.00
453_A	456_I	1.311	1.00
78_L	257_I	1.303	1.00
327_G	356_I	1.300	1.00
78_L	261_I	1.298	1.00
193_G	196_Q	1.295	1.00
91_S	244_G	1.295	1.00
142_V	146_V	1.285	1.00
26_Y	331_R	1.273	1.00
394_A	434_L	1.263	1.00
412_A	415_V	1.263	1.00
266_L	270_G	1.263	1.00
448_T	454_L	1.257	1.00
421_G	425_T	1.257	1.00
96_S	100_E	1.246	1.00
248_D	255_K	1.242	1.00
178_V	182_V	1.235	1.00
77_I	397_I	1.229	1.00
457_I	461_L	1.223	1.00
335_M	344_A	1.221	1.00
129_V	312_L	1.217	1.00
405_K	408_K	1.216	1.00
205_F	208_I	1.216	1.00
33_R	37_M	1.205	1.00
434_L	438_V	1.194	1.00
50_L	128_A	1.192	1.00
423_P	427_W	1.183	1.00
341_S	345_K	1.182	1.00
140_G	143_P	1.181	1.00
79_R	258_N	1.177	1.00
90_S	96_S	1.175	1.00
43_A	264_I	1.169	1.00
424_F	427_W	1.166	1.00
448_T	452_A	1.162	1.00
158_M	169_M	1.156	1.00
98_A	106_A	1.156	1.00
112_W	458_G	1.149	1.00
193_G	197_P	1.149	1.00
188_G	278_L	1.147	1.00
184_F	188_G	1.144	1.00
145_W	149_L	1.144	1.00
397_I	430_L	1.142	1.00
455_P	458_G	1.138	1.00
247_K	252_M	1.137	1.00
62_A	215_F	1.132	1.00
68_L	269_V	1.132	1.00
80_A	426_S	1.128	1.00
125_D	318_S	1.127	1.00
115_F	330_L	1.118	1.00
105_K	465_W	1.117	1.00
190_V	194_S	1.114	1.00
192_L	277_M	1.112	1.00
35_V	256_A	1.107	1.00
461_L	465_W	1.107	1.00
168_E	172_W	1.104	1.00
30_M	167_A	1.103	1.00
408_K	412_A	1.094	1.00
85_V	97_Y	1.084	1.00
394_A	433_L	1.083	1.00
189_T	193_G	1.083	1.00
59_A	62_A	1.081	1.00
354_A	357_L	1.078	1.00
156_G	160_M	1.076	1.00
462_V	465_W	1.076	1.00
415_V	418_K	1.072	1.00
458_G	465_W	1.068	1.00
400_Q	426_S	1.068	1.00
190_V	195_G	1.066	1.00
169_M	173_F	1.061	1.00
183_T	187_V	1.061	1.00
40_I	263_R	1.061	1.00
421_G	424_F	1.061	1.00
301_P	305_S	1.060	1.00
413_A	416_S	1.059	1.00
30_M	35_V	1.057	1.00
206_H	209_T	1.049	1.00
29_A	247_K	1.047	1.00
444_Y	448_T	1.045	1.00
150_A	154_I	1.042	1.00
90_S	100_E	1.030	1.00
249_P	254_P	1.029	1.00
154_I	316_L	1.027	1.00
38_I	242_A	1.026	1.00
330_L	339_A	1.026	1.00
87_H	413_A	1.026	1.00
194_S	197_P	1.023	1.00
223_L	435_S	1.022	1.00
62_A	222_A	1.021	1.00
100_E	407_I	1.017	1.00
422_A	426_S	1.016	1.00
407_I	412_A	1.015	1.00
81_L	94_F	1.014	1.00
130_A	147_F	1.014	1.00
39_A	239_V	1.007	1.00
465_W	468_V	1.007	1.00
273_V	277_M	1.002	1.00
37_M	171_F	1.002	1.00
448_T	455_P	1.000	1.00
456_I	460_L	0.995	1.00
361_V	365_V	0.992	1.00
459_I	463_I	0.991	1.00
192_L	195_G	0.981	1.00
346_M	350_H	0.981	1.00
163_V	324_Y	0.980	1.00
76_F	425_T	0.978	1.00
168_E	171_F	0.974	1.00
40_I	264_I	0.972	1.00
218_G	221_P	0.971	1.00
182_V	186_V	0.971	1.00
224_V	228_G	0.969	1.00
146_V	150_A	0.969	1.00
407_I	413_A	0.966	1.00
203_T	206_H	0.965	1.00
408_K	415_V	0.965	1.00
173_F	317_S	0.957	1.00
56_L	63_L	0.956	1.00
87_H	415_V	0.955	1.00
99_R	336_G	0.950	1.00
259_S	263_R	0.950	1.00
283_A	297_K	0.949	1.00
133_M	137_G	0.940	1.00
204_G	209_T	0.939	1.00
438_V	442_F	0.939	1.00
210_D	213_G	0.936	1.00
430_L	434_L	0.936	1.00
29_A	164_K	0.935	1.00
234_A	389_I	0.930	1.00
147_F	150_A	0.928	1.00
133_M	312_L	0.923	1.00
33_R	171_F	0.921	1.00
83_E	86_L	0.911	1.00
170_E	320_N	0.911	1.00
360_L	364_V	0.910	1.00
153_T	157_T	0.906	1.00
108_Y	112_W	0.906	1.00
323_L	360_L	0.903	1.00
178_V	267_F	0.902	1.00
243_A	253_V	0.902	1.00
450_T	454_L	0.901	1.00
190_V	193_G	0.900	1.00
455_P	459_I	0.898	1.00
429_T	433_L	0.898	1.00
295_F	298_L	0.895	1.00
464_G	467_G	0.893	1.00
106_A	395_F	0.891	1.00
149_L	368_F	0.889	1.00
77_I	433_L	0.880	1.00
404_R	408_K	0.880	1.00
449_Y	456_I	0.877	1.00
34_Q	168_E	0.875	1.00
160_M	351_V	0.866	1.00
185_L	189_T	0.865	1.00
435_S	438_V	0.864	1.00
302_Y	305_S	0.864	1.00
84_L	400_Q	0.861	1.00
454_L	457_I	0.852	1.00
238_M	325_C	0.849	1.00
299_G	303_I	0.849	1.00
185_L	274_L	0.848	1.00
265_G	269_V	0.847	1.00
448_T	453_A	0.847	1.00
124_V	382_L	0.844	1.00
215_F	222_A	0.844	1.00
300_V	303_I	0.842	1.00
353_Y	357_L	0.839	1.00
112_W	339_A	0.838	1.00
343_M	354_A	0.836	1.00
92_G	96_S	0.836	1.00
58_M	61_P	0.835	1.00
453_A	457_I	0.835	1.00
280_P	297_K	0.835	1.00
414_D	418_K	0.833	1.00
287_G	293_T	0.831	1.00
155_V	320_N	0.831	1.00
141_G	144_Q	0.830	1.00
129_V	315_A	0.830	1.00
205_F	209_T	0.827	1.00
289_S	292_V	0.825	1.00
157_T	160_M	0.825	1.00
433_L	436_V	0.824	1.00
423_P	426_S	0.819	1.00
437_L	440_M	0.818	1.00
75_F	79_R	0.818	1.00
207_L	210_D	0.818	1.00
103_G	466_F	0.817	1.00
450_T	455_P	0.816	1.00
290_P	294_F	0.815	1.00
137_G	140_G	0.814	1.00
444_Y	449_Y	0.813	1.00
121_T	124_V	0.811	1.00
42_G	321_S	0.806	1.00
124_V	231_F	0.805	1.00
283_A	286_A	0.805	1.00
71_G	233_F	0.804	1.00
206_H	210_D	0.804	1.00
134_H	144_Q	0.802	1.00
161_I	165_W	0.801	1.00
453_A	458_G	0.800	1.00
185_L	271_S	0.799	1.00
64_A	276_V	0.798	1.00
95_V	332_S	0.796	1.00
459_I	462_V	0.794	1.00
130_A	148_A	0.792	1.00
86_L	416_S	0.788	1.00
145_W	367_V	0.788	1.00
347_S	350_H	0.786	1.00
208_I	211_N	0.785	1.00
192_L	196_Q	0.783	1.00
426_S	430_L	0.780	1.00
401_M	405_K	0.779	1.00
280_P	283_A	0.776	1.00
29_A	163_V	0.775	1.00
32_N	256_A	0.773	1.00
135_Y	138_A	0.772	1.00
105_K	109_V	0.772	1.00
449_Y	455_P	0.769	1.00
394_A	398_V	0.769	1.00
422_A	425_T	0.768	1.00
167_A	171_F	0.767	1.00
155_V	323_L	0.760	1.00
284_Y	287_G	0.760	1.00
413_A	418_K	0.756	1.00
327_G	355_G	0.753	1.00
98_A	399_C	0.753	1.00
401_M	426_S	0.752	1.00
286_A	290_P	0.750	1.00
219_L	222_A	0.750	1.00
191_F	194_S	0.745	1.00
61_P	276_V	0.744	1.00
29_A	33_R	0.743	1.00
451_I	456_I	0.740	1.00
203_T	207_L	0.738	1.00
145_W	148_A	0.737	1.00
160_M	347_S	0.733	1.00
399_C	403_L	0.729	1.00
191_F	197_P	0.728	1.00
278_L	294_F	0.726	1.00
36_Q	256_A	0.726	1.00
26_Y	29_A	0.723	1.00
334_A	343_M	0.721	1.00
436_V	440_M	0.720	1.00
339_A	343_M	0.720	1.00
237_E	241_T	0.717	1.00
207_L	211_N	0.717	1.00
433_L	437_L	0.716	1.00
426_S	440_M	0.715	1.00
63_L	272_V	0.713	1.00
361_V	364_V	0.712	1.00
444_Y	450_T	0.710	1.00
384_F	388_G	0.710	1.00
165_W	168_E	0.709	1.00
33_R	168_E	0.708	1.00
415_V	419_L	0.708	1.00
184_F	295_F	0.707	1.00
460_L	463_I	0.705	1.00
84_L	97_Y	0.705	1.00
43_A	260_V	0.705	1.00
348_R	353_Y	0.704	1.00
114_Y	118_W	0.704	1.00
189_T	270_G	0.704	1.00
92_G	95_V	0.702	1.00
448_T	461_L	0.702	1.00
352_P	355_G	0.702	1.00
68_L	72_L	0.701	1.00
285_Q	288_Q	0.701	1.00
119_A	362_V	0.700	1.00
82_G	86_L	0.699	1.00
401_M	423_P	0.698	1.00
75_F	258_N	0.697	1.00
450_T	456_I	0.696	1.00
81_L	396_I	0.696	1.00
455_P	462_V	0.695	1.00
291_F	295_F	0.693	1.00
263_R	267_F	0.692	1.00
290_P	295_F	0.691	1.00
458_G	467_G	0.691	1.00
159_N	356_I	0.691	1.00
212_G	215_F	0.690	1.00
448_T	462_V	0.690	1.00
52_A	55_R	0.688	1.00
250_Q	416_S	0.685	1.00
129_V	316_L	0.684	1.00
121_T	385_A	0.684	1.00
403_L	407_I	0.683	1.00
153_T	156_G	0.681	1.00
429_T	432_F	0.680	1.00
120_M	384_F	0.679	1.00
42_G	322_G	0.679	1.00
52_A	272_V	0.678	1.00
65_L	69_I	0.675	1.00
177_K	314_A	0.675	1.00
65_L	222_A	0.672	1.00
254_P	257_I	0.672	1.00
130_A	133_M	0.670	1.00
400_Q	404_R	0.669	1.00
427_W	430_L	0.668	1.00
204_G	208_I	0.668	1.00
123_I	381_V	0.667	1.00
44_I	47_G	0.665	1.00
126_I	130_A	0.665	1.00
64_A	68_L	0.664	1.00
274_L	277_M	0.662	1.00
449_Y	454_L	0.661	1.00
54_A	379_E	0.661	1.00
152_L	364_V	0.659	1.00
102_L	105_K	0.658	1.00
460_L	466_F	0.657	1.00
450_T	457_I	0.657	1.00
162_G	165_W	0.657	1.00
408_K	413_A	0.657	1.00
65_L	68_L	0.656	1.00
286_A	289_S	0.656	1.00
130_A	144_Q	0.655	1.00
62_A	214_F	0.654	1.00
118_W	322_G	0.654	1.00
152_L	367_V	0.654	1.00
74_S	236_I	0.653	1.00
205_F	277_M	0.653	1.00
70_C	230_V	0.651	1.00
343_M	355_G	0.649	1.00
240_G	257_I	0.648	1.00
342_F	358_A	0.648	1.00
241_T	325_C	0.648	1.00
117_N	389_I	0.648	1.00
54_A	58_M	0.647	1.00
131_L	144_Q	0.647	1.00
191_F	196_Q	0.647	1.00
133_M	151_A	0.645	1.00
213_G	216_P	0.643	1.00
387_L	437_L	0.643	1.00
78_L	236_I	0.642	1.00
84_L	101_F	0.642	1.00
121_T	125_D	0.641	1.00
48_L	271_S	0.641	1.00
76_F	429_T	0.639	1.00
87_H	416_S	0.639	1.00
449_Y	460_L	0.638	1.00
85_V	240_G	0.638	1.00
134_H	138_A	0.637	1.00
370_N	377_V	0.635	1.00
64_A	67_Y	0.633	1.00
192_L	197_P	0.631	1.00
101_F	403_L	0.631	1.00
388_G	392_S	0.631	1.00
160_M	356_I	0.631	1.00
448_T	465_W	0.629	1.00
210_D	214_F	0.628	1.00
187_V	191_F	0.626	1.00
420_P	424_F	0.624	1.00
219_L	223_L	0.624	1.00
129_V	133_M	0.623	1.00
462_V	467_G	0.623	1.00
76_F	80_A	0.623	1.00
444_Y	451_I	0.622	1.00
102_L	399_C	0.621	1.00
448_T	456_I	0.620	1.00
36_Q	39_A	0.620	1.00
326_T	330_L	0.620	1.00
463_I	466_F	0.619	1.00
101_F	402_R	0.618	1.00
271_S	275_L	0.618	1.00
263_R	266_L	0.616	1.00
26_Y	245_E	0.616	1.00
377_V	380_I	0.616	1.00
244_G	331_R	0.616	1.00
419_L	422_A	0.615	1.00
91_S	331_R	0.614	1.00
125_D	128_A	0.613	1.00
365_V	368_F	0.612	1.00
330_L	358_A	0.612	1.00
422_A	427_W	0.611	1.00
160_M	349_Q	0.611	1.00
139_F	143_P	0.609	1.00
87_H	403_L	0.607	1.00
342_F	346_M	0.606	1.00
283_A	287_G	0.606	1.00
180_A	306_I	0.605	1.00
159_N	324_Y	0.602	1.00
39_A	43_A	0.602	1.00
449_Y	458_G	0.602	1.00
127_T	381_V	0.601	1.00
421_G	426_S	0.598	1.00
64_A	269_V	0.598	1.00
26_Y	328_R	0.597	1.00
461_L	467_G	0.596	1.00
285_Q	289_S	0.596	1.00
337_G	344_A	0.595	1.00
306_I	310_V	0.595	1.00
95_V	99_R	0.595	1.00
44_I	267_F	0.595	1.00
79_R	420_P	0.594	1.00
135_Y	308_N	0.593	1.00
40_I	174_A	0.592	1.00
155_V	316_L	0.590	1.00
234_A	393_W	0.588	1.00
119_A	359_T	0.588	1.00
165_W	169_M	0.587	1.00
246_C	253_V	0.586	1.00
176_I	310_V	0.586	1.00
284_Y	290_P	0.586	1.00
223_L	439_L	0.581	1.00
253_V	257_I	0.578	1.00
438_V	441_A	0.578	1.00
85_V	253_V	0.576	1.00
58_M	224_V	0.576	1.00
35_V	242_A	0.576	1.00
389_I	392_S	0.573	1.00
51_G	382_L	0.573	1.00
414_D	417_F	0.571	1.00
166_F	324_Y	0.569	1.00
54_A	57_Q	0.569	1.00
95_V	111_G	0.567	1.00
390_I	433_L	0.567	1.00
357_L	360_L	0.567	1.00
328_R	331_R	0.567	1.00
379_E	382_L	0.567	1.00
353_Y	356_I	0.566	1.00
151_A	319_L	0.566	1.00
67_Y	232_A	0.565	1.00
144_Q	148_A	0.564	1.00
58_M	225_L	0.563	1.00
113_M	391_A	0.562	1.00
439_L	443_D	0.561	1.00
79_R	425_T	0.555	1.00
451_I	462_V	0.555	1.00
171_F	175_L	0.553	1.00
51_G	54_A	0.552	1.00
271_S	291_F	0.550	1.00
448_T	459_I	0.550	1.00
292_V	296_S	0.549	1.00
40_I	43_A	0.548	1.00
176_I	180_A	0.548	1.00
319_L	322_G	0.548	1.00
182_V	267_F	0.546	1.00
55_R	59_A	0.546	1.00
211_N	216_P	0.545	1.00
125_D	319_L	0.545	1.00
323_L	327_G	0.545	1.00
453_A	464_G	0.543	1.00
128_A	132_Y	0.542	1.00
458_G	463_I	0.541	1.00
223_L	227_Q	0.541	1.00
66_V	69_I	0.541	1.00
26_Y	91_S	0.539	1.00
270_G	274_L	0.537	1.00
82_G	257_I	0.536	1.00
174_A	177_K	0.536	1.00
70_C	233_F	0.536	1.00
346_M	349_Q	0.535	1.00
215_F	218_G	0.535	1.00
309_I	313_T	0.535	1.00
52_A	56_L	0.534	1.00
234_A	237_E	0.533	1.00
221_P	224_V	0.533	1.00
428_L	431_L	0.532	1.00
48_L	52_A	0.531	1.00
248_D	254_P	0.530	1.00
63_L	66_V	0.530	1.00
426_S	433_L	0.529	1.00
460_L	465_W	0.529	1.00
211_N	282_S	0.528	1.00
98_A	107_A	0.528	1.00
259_S	262_W	0.528	1.00
433_L	440_M	0.527	1.00
28_K	247_K	0.526	1.00
113_M	392_S	0.526	1.00
290_P	298_L	0.525	1.00
79_R	417_F	0.525	1.00
61_P	64_A	0.524	1.00
52_A	275_L	0.524	1.00
314_A	317_S	0.524	1.00
404_R	422_A	0.524	1.00
132_Y	311_V	0.523	1.00
450_T	465_W	0.521	1.00
156_G	323_L	0.521	1.00
25_G	28_K	0.518	1.00
88_R	101_F	0.517	1.00
115_F	119_A	0.517	1.00
94_F	237_E	0.515	1.00
29_A	350_H	0.514	1.00
301_P	304_G	0.514	1.00
323_L	359_T	0.514	1.00
305_S	308_N	0.512	1.00
90_S	244_G	0.511	1.00
295_F	300_V	0.510	1.00
94_F	396_I	0.510	1.00
294_F	298_L	0.509	1.00
431_L	434_L	0.509	1.00
24_E	27_H	0.508	1.00
330_L	334_A	0.508	1.00
358_A	362_V	0.508	1.00
403_L	408_K	0.508	1.00
458_G	466_F	0.508	1.00
197_P	277_M	0.507	1.00
61_P	281_W	0.506	1.00
142_V	147_F	0.506	1.00
462_V	468_V	0.505	1.00
172_W	175_L	0.504	1.00
87_H	408_K	0.504	1.00
80_A	429_T	0.504	1.00
41_G	174_A	0.503	1.00
192_L	274_L	0.503	1.00
376_R	379_E	0.503	1.00
110_A	392_S	0.503	1.00
107_A	111_G	0.502	1.00
249_P	252_M	0.501	1.00
197_P	276_V	0.501	1.00
86_L	250_Q	0.501	1.00
220_L	224_V	0.501	1.00
234_A	385_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8397	100	0.357	Contact Map
3giaA	1	0.8577	100	0.396	Contact Map
4djkA	2	0.8497	100	0.397	Contact Map
2jlnA	1	0.8717	99.3	0.844	Contact Map
3dh4A	3	0.8758	98.9	0.869	Contact Map
2xq2A	2	0.8758	98.9	0.871	Contact Map
4wgvA	2	0.7455	98.1	0.899	Contact Map
4xp4A	1	0.8798	97.6	0.91	Contact Map
4us3A	1	0.7896	97.2	0.917	Contact Map
2a65A	2	0.8637	97	0.918	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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