GREMLIN Database
YDEQ - Uncharacterized fimbrial-like protein YdeQ
UniProt: P77588 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13799
Length: 304 (290)
Sequences: 874 (809)
Seq/√Len: 47.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
197_P293_V5.1361.00
98_L102_N4.4341.00
98_L103_V3.8011.00
235_N293_V3.6661.00
95_K99_Y3.4901.00
232_V282_G3.4901.00
248_V295_S3.4801.00
97_S102_N3.4251.00
96_G99_Y3.2721.00
98_L101_N3.2661.00
249_T280_T3.0981.00
194_V205_I3.0771.00
96_G102_N2.9401.00
93_S97_S2.9221.00
95_K98_L2.8121.00
53_G56_L2.6451.00
44_V49_V2.6331.00
51_Q56_L2.6281.00
232_V247_G2.6191.00
244_S289_S2.6191.00
235_N242_K2.5931.00
251_M280_T2.5601.00
49_V56_L2.4121.00
99_Y102_N2.2851.00
196_L293_V2.2711.00
207_L299_V2.2351.00
51_Q55_N2.2061.00
45_N49_V2.1611.00
137_A140_G2.1501.00
96_G101_N2.1231.00
51_Q54_Q2.0341.00
99_Y103_V2.0270.99
97_S101_N2.0230.99
136_G140_G2.0180.99
197_P235_N1.9730.99
44_V48_P1.9590.99
96_G103_V1.9500.99
44_V56_L1.9140.99
235_N294_Q1.8280.99
104_T108_P1.8190.99
45_N48_P1.8070.99
227_D230_R1.7910.99
136_G139_G1.7770.99
260_G300_T1.7650.99
49_V53_G1.7470.98
98_L104_T1.7340.98
223_G233_F1.7330.98
192_V299_V1.7040.98
218_S302_I1.6830.98
48_P51_Q1.6730.98
49_V52_P1.6710.98
97_S103_V1.6440.98
95_K102_N1.6270.98
212_S223_G1.6190.97
90_S93_S1.6130.97
94_Y97_S1.6070.97
197_P294_Q1.5660.97
283_Q288_V1.5600.97
189_S192_V1.5450.97
222_S260_G1.5400.97
42_V45_N1.5280.96
48_P52_P1.5190.96
88_A92_Q1.5140.96
207_L250_L1.5010.96
95_K103_V1.4710.96
93_S102_N1.4470.95
281_Y293_V1.4440.95
231_Q259_T1.4410.95
89_G92_Q1.4200.95
44_V51_Q1.4150.94
42_V49_V1.4120.94
42_V48_P1.4060.94
220_Y262_N1.3960.94
48_P53_G1.3800.94
89_G93_S1.3690.93
207_L277_L1.3490.93
205_I299_V1.3460.93
223_G261_E1.3230.92
219_F299_V1.3190.92
95_K101_N1.3160.92
132_I136_G1.3090.92
94_Y99_Y1.3040.92
212_S215_Q1.2990.91
93_S96_G1.2820.91
42_V46_L1.2660.90
44_V53_G1.2660.90
205_I221_L1.2620.90
238_P241_T1.2610.90
233_F297_I1.2600.90
223_G231_Q1.2580.90
38_G42_V1.2560.90
194_V299_V1.2540.90
19_A22_V1.2350.89
138_A141_V1.2290.89
258_A261_E1.2210.89
236_T293_V1.2170.89
206_P276_G1.2170.89
183_G209_V1.2160.88
45_N51_Q1.2140.88
48_P56_L1.2110.88
130_L134_P1.1920.87
223_G228_S1.1850.87
130_L135_V1.1830.87
223_G234_A1.1750.87
47_D50_I1.1730.87
133_T139_G1.1640.86
84_G87_F1.1530.86
245_G303_Y1.1430.85
273_V276_G1.1390.85
38_G53_G1.1380.85
219_F268_V1.1330.85
94_Y98_L1.1140.84
223_G262_N1.1120.84
134_P139_G1.1050.83
49_V55_N1.0990.83
230_R301_F1.0950.83
139_G142_V1.0690.81
41_S44_V1.0560.80
98_L105_Y1.0370.79
222_S300_T1.0330.79
131_Y135_V1.0300.79
235_N238_P1.0300.79
96_G104_T1.0240.78
184_G301_F1.0170.78
46_L49_V1.0150.77
98_L106_P1.0130.77
219_F280_T1.0130.77
132_I137_A1.0100.77
226_T230_R1.0090.77
38_G45_N1.0050.77
196_L294_Q0.9970.76
273_V277_L0.9960.76
133_T136_G0.9960.76
181_P213_S0.9950.76
241_T292_T0.9870.75
104_T107_F0.9820.75
221_L299_V0.9780.75
18_M22_V0.9740.75
223_G229_S0.9720.74
192_V207_L0.9690.74
277_L299_V0.9670.74
40_T53_G0.9650.74
237_A275_L0.9610.74
184_G216_K0.9590.73
50_I56_L0.9560.73
52_P56_L0.9440.72
144_K151_R0.9430.72
137_A146_G0.9420.72
223_G259_T0.9410.72
128_L134_P0.9370.72
45_N53_G0.9340.71
197_P236_T0.9310.71
226_T260_G0.9280.71
262_N302_I0.9280.71
105_Y108_P0.9260.71
231_Q256_I0.9160.70
223_G282_G0.9150.70
257_L295_S0.9080.69
91_L94_Y0.9070.69
223_G301_F0.9040.69
236_T294_Q0.9000.68
135_V140_G0.8990.68
29_V32_G0.8940.68
283_Q293_V0.8920.68
228_S260_G0.8890.68
217_L267_T0.8880.67
221_L263_V0.8870.67
93_S98_L0.8870.67
89_G97_S0.8810.67
46_L56_L0.8800.67
38_G51_Q0.8780.67
233_F259_T0.8710.66
242_K292_T0.8690.66
184_G298_G0.8670.66
222_S225_T0.8610.65
44_V52_P0.8480.64
195_D281_Y0.8450.64
231_Q299_V0.8420.63
94_Y102_N0.8410.63
83_Q87_F0.8400.63
223_G260_G0.8390.63
223_G230_R0.8380.63
212_S219_F0.8380.63
93_S101_N0.8380.63
223_G275_L0.8370.63
219_F263_V0.8350.63
183_G221_L0.8340.63
45_N55_N0.8330.62
187_V192_V0.8310.62
134_P137_A0.8300.62
40_T44_V0.8200.61
221_L277_L0.8200.61
195_D253_N0.8140.61
250_L256_I0.8110.60
48_P55_N0.8090.60
89_G94_Y0.8050.60
99_Y106_P0.8040.60
209_V221_L0.8010.59
235_N245_G0.7970.59
252_R263_V0.7970.59
142_V146_G0.7960.59
187_V301_F0.7940.59
219_F223_G0.7910.58
10_L14_Y0.7890.58
27_C66_C0.7850.58
205_I277_L0.7800.57
90_S94_Y0.7710.56
46_L52_P0.7700.56
184_G213_S0.7660.56
150_A155_Y0.7650.56
209_V293_V0.7640.56
15_L21_K0.7600.55
249_T282_G0.7570.55
241_T263_V0.7530.55
17_L21_K0.7530.55
155_Y158_A0.7490.54
196_L295_S0.7470.54
231_Q258_A0.7450.54
216_K230_R0.7440.54
232_V249_T0.7410.54
20_G23_F0.7390.53
224_A296_V0.7360.53
246_V298_G0.7360.53
88_A93_S0.7320.53
184_G256_I0.7290.52
46_L50_I0.7250.52
102_N105_Y0.7210.52
46_L86_A0.7210.52
184_G215_Q0.7200.51
268_V271_S0.7190.51
15_L19_A0.7180.51
187_V300_T0.7150.51
136_G143_I0.7130.51
192_V205_I0.7130.51
269_N295_S0.7110.51
236_T296_V0.7100.50
209_V280_T0.7090.50
204_E278_S0.7070.50
217_L223_G0.7070.50
184_G214_E0.7070.50
281_Y303_Y0.7060.50
281_Y284_T0.7060.50
96_G100_W0.7050.50
208_G274_P0.7030.50
250_L277_L0.7020.50
242_K262_N0.7020.50
132_I135_V0.7020.50
280_T293_V0.6970.49
105_Y111_T0.6950.49
243_A281_Y0.6950.49
213_S216_K0.6930.49
207_L211_C0.6920.49
168_F172_I0.6910.49
130_L133_T0.6900.48
86_A89_G0.6880.48
38_G44_V0.6880.48
131_Y140_G0.6870.48
238_P275_L0.6860.48
44_V50_I0.6860.48
90_S97_S0.6850.48
223_G235_N0.6850.48
44_V55_N0.6840.48
192_V296_V0.6830.48
123_P126_L0.6810.48
135_V139_G0.6810.48
41_S45_N0.6790.47
214_E233_F0.6770.47
41_S49_V0.6770.47
131_Y134_P0.6750.47
141_V144_K0.6740.47
231_Q261_E0.6720.47
204_E241_T0.6710.47
199_F293_V0.6700.46
14_Y23_F0.6680.46
46_L91_L0.6660.46
249_T256_I0.6640.46
257_L266_G0.6640.46
113_T116_L0.6580.45
94_Y101_N0.6560.45
92_Q98_L0.6560.45
91_L95_K0.6540.45
183_G266_G0.6500.44
176_N184_G0.6480.44
134_P140_G0.6480.44
281_Y294_Q0.6460.44
235_N259_T0.6460.44
283_Q290_A0.6440.44
222_S282_G0.6430.44
199_F233_F0.6420.44
225_T301_F0.6410.44
45_N52_P0.6400.43
158_A164_N0.6400.43
261_E302_I0.6390.43
13_I16_L0.6380.43
98_L107_F0.6370.43
218_S300_T0.6370.43
38_G56_L0.6360.43
261_E282_G0.6360.43
216_K232_V0.6340.43
256_I259_T0.6330.43
188_D210_Y0.6330.43
262_N300_T0.6330.43
218_S221_L0.6320.43
218_S263_V0.6290.42
148_V158_A0.6290.42
91_L97_S0.6280.42
132_I158_A0.6260.42
142_V147_E0.6260.42
198_D293_V0.6240.42
238_P242_K0.6230.42
38_G41_S0.6220.42
232_V284_T0.6210.42
226_T261_E0.6190.41
87_F91_L0.6180.41
133_T140_G0.6130.41
91_L96_G0.6120.41
228_S262_N0.6090.40
140_G143_I0.6070.40
218_S265_L0.6070.40
136_G142_V0.6000.40
205_I250_L0.5960.39
41_S52_P0.5940.39
254_G278_S0.5940.39
37_A51_Q0.5890.39
129_K133_T0.5890.39
208_G212_S0.5880.38
284_T303_Y0.5880.38
221_L250_L0.5870.38
192_V233_F0.5850.38
66_C246_V0.5850.38
204_E207_L0.5820.38
28_N109_L0.5820.38
222_S297_I0.5820.38
39_T82_V0.5800.38
76_T86_A0.5800.38
217_L268_V0.5790.38
284_T289_S0.5780.38
249_T303_Y0.5780.38
8_K246_V0.5780.38
192_V197_P0.5780.38
90_S95_K0.5770.37
61_S65_S0.5760.37
215_Q219_F0.5750.37
185_C211_C0.5740.37
251_M282_G0.5730.37
192_V199_F0.5710.37
231_Q248_V0.5710.37
194_V250_L0.5680.37
30_D34_S0.5670.36
9_V21_K0.5670.36
42_V50_I0.5660.36
250_L297_I0.5660.36
205_I232_V0.5660.36
184_G210_Y0.5630.36
213_S268_V0.5620.36
109_L118_I0.5620.36
229_S262_N0.5610.36
22_V28_N0.5600.36
73_W83_Q0.5600.36
113_T120_D0.5600.36
97_S104_T0.5590.36
185_C291_G0.5580.36
250_L296_V0.5550.35
209_V249_T0.5550.35
205_I282_G0.5550.35
188_D219_F0.5550.35
97_S105_Y0.5530.35
248_V277_L0.5520.35
39_T43_Y0.5520.35
228_S234_A0.5500.35
12_G15_L0.5480.35
192_V300_T0.5480.35
112_N115_V0.5480.35
141_V150_A0.5480.35
216_K251_M0.5480.35
192_V225_T0.5480.35
43_Y49_V0.5470.35
139_G144_K0.5460.35
184_G233_F0.5460.35
247_G277_L0.5460.35
95_K104_T0.5460.35
114_N117_D0.5460.35
31_G269_N0.5460.35
11_F14_Y0.5450.34
268_V273_V0.5440.34
215_Q297_I0.5400.34
224_A234_A0.5390.34
38_G52_P0.5390.34
31_G38_G0.5370.34
141_V152_I0.5360.34
48_P301_F0.5360.34
40_T43_Y0.5360.34
283_Q289_S0.5350.34
212_S268_V0.5340.33
223_G226_T0.5340.33
223_G242_K0.5320.33
52_P55_N0.5310.33
192_V301_F0.5300.33
233_F282_G0.5290.33
86_A90_S0.5290.33
200_P203_A0.5290.33
37_A40_T0.5290.33
31_G34_S0.5280.33
225_T230_R0.5280.33
267_T300_T0.5280.33
242_K299_V0.5250.33
125_P130_L0.5220.32
130_L140_G0.5220.32
88_A91_L0.5220.32
182_T249_T0.5210.32
12_G38_G0.5200.32
42_V56_L0.5190.32
243_A303_Y0.5190.32
44_V54_Q0.5180.32
226_T289_S0.5160.32
90_S99_Y0.5160.32
266_G300_T0.5160.32
233_F236_T0.5160.32
223_G263_V0.5160.32
94_Y100_W0.5150.32
38_G48_P0.5150.32
127_P130_L0.5130.32
148_V296_V0.5130.32
9_V244_S0.5110.31
9_V14_Y0.5090.31
38_G49_V0.5090.31
141_V176_N0.5090.31
101_N104_T0.5080.31
283_Q300_T0.5080.31
97_S100_W0.5070.31
223_G300_T0.5060.31
230_R262_N0.5040.31
147_E161_G0.5020.31
236_T242_K0.5020.31
176_N182_T0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3jwnH 1 0.9112 100 0.419 Contact Map
1ze3H 1 0.4013 99.9 0.578 Contact Map
5afoA 1 0.8914 99.9 0.58 Contact Map
2jmrA 1 0.4441 99.9 0.629 Contact Map
3bwuF 1 0.3717 99.9 0.633 Contact Map
2xg5B 1 0.4079 99.9 0.643 Contact Map
2jtyA 1 0.4572 99.9 0.647 Contact Map
4dwhB 1 0.3882 99.9 0.651 Contact Map
3bfqG 1 0.3849 99.8 0.652 Contact Map
1pdkB 1 0.4013 99.8 0.656 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0097 seconds.