YDEP - ECOLI - GREMLIN Contacts

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YDEP - Protein YdeP

UniProt:	P77561	Sequences: MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKPEGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHELEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAAFLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHNPGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYYNVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEWKDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNIGKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPHAPGHAAIASMQAICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILPVLGRSEIDMQKNGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQAALPQSVVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANFITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPSN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13798
Length:	759 (654)
Sequences:	9422 (5857)
Seq/√Len:	229.0

ECOLI - YDEP FDHF DMSA NAPA YNFF YNFE TORA TORZ BISC FDNG FDOG NUOG
BACSU - NASC YOAE YJGC YYAE FDHL
HALSA - DMSA
SULSO - Q97ZA1 Q97V13 Q97XX8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
111_Q	124_P	5.612	1.00
132_D	561_A	4.377	1.00
686_V	705_S	4.312	1.00
693_N	756_E	4.006	1.00
549_K	557_G	3.685	1.00
690_E	757_P	3.509	1.00
297_R	353_D	3.390	1.00
137_R	140_S	3.201	1.00
693_N	700_D	3.173	1.00
289_G	337_I	3.122	1.00
335_K	345_Q	3.109	1.00
642_L	684_C	3.103	1.00
680_Q	714_V	3.074	1.00
553_A	557_G	3.065	1.00
312_D	316_Q	2.908	1.00
539_G	542_K	2.877	1.00
133_E	505_Y	2.877	1.00
293_L	297_R	2.874	1.00
320_V	619_S	2.784	1.00
126_S	129_Q	2.765	1.00
291_M	325_L	2.762	1.00
695_I	756_E	2.755	1.00
134_I	505_Y	2.718	1.00
131_F	561_A	2.716	1.00
215_I	287_L	2.674	1.00
292_R	296_E	2.660	1.00
695_I	754_E	2.650	1.00
679_K	713_V	2.639	1.00
488_H	503_H	2.606	1.00
116_D	123_K	2.592	1.00
338_E	345_Q	2.580	1.00
239_K	354_A	2.566	1.00
141_Y	146_Q	2.558	1.00
274_A	350_E	2.557	1.00
291_M	388_M	2.551	1.00
619_S	623_N	2.510	1.00
210_D	360_R	2.503	1.00
242_A	272_A	2.482	1.00
692_V	705_S	2.453	1.00
131_F	557_G	2.443	1.00
344_S	347_Q	2.439	1.00
286_L	341_S	2.438	1.00
676_M	755_L	2.436	1.00
125_L	505_Y	2.433	1.00
696_A	753_V	2.409	1.00
114_K	133_E	2.404	1.00
345_Q	349_A	2.401	1.00
347_Q	350_E	2.353	1.00
114_K	505_Y	2.329	1.00
676_M	705_S	2.326	1.00
681_A	707_R	2.325	1.00
671_R	704_S	2.318	1.00
111_Q	546_V	2.258	1.00
333_E	336_D	2.256	1.00
114_K	125_L	2.256	1.00
208_K	395_P	2.252	1.00
310_L	315_I	2.250	1.00
308_S	312_D	2.219	1.00
138_L	458_A	2.215	1.00
295_I	322_F	2.161	1.00
134_I	487_V	2.114	1.00
695_I	700_D	2.107	1.00
297_R	309_L	2.102	1.00
209_C	212_V	2.099	1.00
313_E	317_T	2.092	1.00
688_N	707_R	2.086	1.00
457_R	484_D	2.078	1.00
684_C	754_E	2.076	1.00
557_G	561_A	2.068	1.00
683_I	713_V	2.034	1.00
211_L	354_A	2.029	1.00
133_E	137_R	2.001	1.00
472_D	737_D	1.999	1.00
350_E	354_A	1.972	1.00
141_Y	458_A	1.967	1.00
276_Y	343_L	1.959	1.00
276_Y	351_L	1.956	1.00
686_V	692_V	1.947	1.00
544_A	548_L	1.938	1.00
674_V	716_Y	1.937	1.00
274_A	347_Q	1.924	1.00
116_D	119_S	1.917	1.00
572_Y	575_E	1.916	1.00
286_L	348_I	1.915	1.00
674_V	692_V	1.896	1.00
125_L	133_E	1.880	1.00
233_L	238_A	1.878	1.00
691_R	702_K	1.867	1.00
460_I	489_V	1.856	1.00
703_R	718_M	1.843	1.00
310_L	322_F	1.840	1.00
674_V	694_L	1.836	1.00
292_R	334_W	1.823	1.00
211_L	241_I	1.814	1.00
295_I	326_R	1.808	1.00
124_P	546_V	1.802	1.00
679_K	682_K	1.784	1.00
327_R	330_L	1.782	1.00
132_D	136_A	1.766	1.00
114_K	123_K	1.760	1.00
693_N	702_K	1.757	1.00
297_R	349_A	1.722	1.00
282_G	340_I	1.720	1.00
688_N	706_R	1.718	1.00
687_K	690_E	1.701	1.00
477_A	481_T	1.698	1.00
110_T	545_G	1.685	1.00
674_V	718_M	1.684	1.00
394_K	397_A	1.679	1.00
309_L	356_A	1.675	1.00
296_E	330_L	1.675	1.00
234_V	273_S	1.666	1.00
274_A	354_A	1.664	1.00
293_L	349_A	1.660	1.00
243_I	286_L	1.646	1.00
337_I	348_I	1.635	1.00
146_Q	457_R	1.625	1.00
478_V	481_T	1.624	1.00
557_G	560_Q	1.622	1.00
516_D	539_G	1.617	1.00
293_L	353_D	1.615	1.00
421_S	425_L	1.612	1.00
294_L	310_L	1.610	1.00
355_Y	389_K	1.609	1.00
315_I	322_F	1.601	1.00
590_E	593_D	1.595	1.00
113_L	506_I	1.595	1.00
319_T	624_F	1.589	1.00
483_L	486_A	1.574	1.00
338_E	344_S	1.573	1.00
293_L	334_W	1.573	1.00
353_D	357_A	1.563	1.00
355_Y	361_T	1.563	1.00
510_L	550_S	1.541	1.00
125_L	129_Q	1.539	1.00
676_M	716_Y	1.539	1.00
129_Q	133_E	1.534	1.00
142_S	457_R	1.534	1.00
691_R	704_S	1.533	1.00
642_L	716_Y	1.531	1.00
213_I	351_L	1.525	1.00
335_K	349_A	1.523	1.00
294_L	356_A	1.510	1.00
295_I	329_V	1.500	1.00
338_E	348_I	1.492	1.00
716_Y	753_V	1.491	1.00
675_F	708_M	1.490	1.00
286_L	351_L	1.490	1.00
426_A	430_E	1.481	1.00
309_L	353_D	1.478	1.00
326_R	330_L	1.476	1.00
274_A	351_L	1.468	1.00
485_L	505_Y	1.464	1.00
134_I	507_L	1.460	1.00
167_A	172_S	1.458	1.00
647_V	717_P	1.448	1.00
388_M	624_F	1.447	1.00
642_L	680_Q	1.437	1.00
320_V	623_N	1.434	1.00
136_A	140_S	1.434	1.00
213_I	243_I	1.428	1.00
324_E	327_R	1.422	1.00
296_E	349_A	1.413	1.00
59_H	76_E	1.411	1.00
211_L	351_L	1.410	1.00
493_L	500_T	1.406	1.00
285_A	340_I	1.390	1.00
112_P	127_W	1.381	1.00
321_G	324_E	1.377	1.00
571_E	575_E	1.377	1.00
290_M	351_L	1.374	1.00
293_L	296_E	1.359	1.00
369_I	382_L	1.354	1.00
148_E	456_A	1.353	1.00
149_F	167_A	1.347	1.00
113_L	124_P	1.346	1.00
60_S	73_I	1.346	1.00
292_R	330_L	1.344	1.00
678_A	709_D	1.342	1.00
629_G	634_P	1.337	1.00
452_C	475_A	1.335	1.00
166_F	562_A	1.332	1.00
461_C	486_A	1.328	1.00
138_L	487_V	1.328	1.00
276_Y	347_Q	1.325	1.00
282_G	341_S	1.322	1.00
491_T	511_G	1.321	1.00
701_G	718_M	1.318	1.00
143_D	146_Q	1.314	1.00
99_G	664_Y	1.314	1.00
549_K	553_A	1.313	1.00
493_L	506_I	1.312	1.00
550_S	553_A	1.308	1.00
358_A	361_T	1.305	1.00
245_P	275_Y	1.303	1.00
637_A	697_L	1.302	1.00
293_L	309_L	1.298	1.00
582_N	585_E	1.297	1.00
684_C	755_L	1.295	1.00
313_E	316_Q	1.294	1.00
58_K	73_I	1.288	1.00
322_F	326_R	1.280	1.00
336_D	339_R	1.276	1.00
577_Y	581_R	1.273	1.00
674_V	703_R	1.272	1.00
61_A	74_A	1.269	1.00
133_E	485_L	1.266	1.00
332_S	340_I	1.253	1.00
135_G	561_A	1.251	1.00
131_F	549_K	1.250	1.00
290_M	355_Y	1.249	1.00
578_D	581_R	1.249	1.00
189_G	379_V	1.248	1.00
291_M	329_V	1.246	1.00
332_S	337_I	1.242	1.00
673_V	706_R	1.241	1.00
210_D	358_A	1.235	1.00
295_I	310_L	1.234	1.00
332_S	336_D	1.227	1.00
429_G	435_T	1.225	1.00
475_A	478_V	1.223	1.00
278_V	343_L	1.217	1.00
472_D	475_A	1.216	1.00
148_E	447_S	1.215	1.00
342_G	712_K	1.213	1.00
489_V	509_V	1.213	1.00
147_V	458_A	1.205	1.00
489_V	554_V	1.204	1.00
391_N	397_A	1.201	1.00
642_L	754_E	1.200	1.00
677_S	713_V	1.199	1.00
241_I	351_L	1.197	1.00
74_A	81_Q	1.195	1.00
278_V	282_G	1.192	1.00
578_D	582_N	1.191	1.00
708_M	711_L	1.191	1.00
315_I	624_F	1.179	1.00
116_D	121_C	1.176	1.00
290_M	352_A	1.172	1.00
205_D	208_K	1.171	1.00
443_A	446_A	1.170	1.00
129_Q	505_Y	1.170	1.00
488_H	500_T	1.169	1.00
312_D	326_R	1.162	1.00
210_D	359_E	1.161	1.00
449_Q	475_A	1.161	1.00
595_N	598_I	1.155	1.00
309_L	357_A	1.154	1.00
242_A	269_T	1.148	1.00
510_L	548_L	1.145	1.00
422_A	425_L	1.137	1.00
639_N	754_E	1.136	1.00
137_R	484_D	1.136	1.00
293_L	348_I	1.126	1.00
58_K	75_W	1.126	1.00
458_A	485_L	1.124	1.00
462_M	555_V	1.116	1.00
115_Y	122_Y	1.116	1.00
212_V	238_A	1.116	1.00
346_T	349_A	1.116	1.00
287_L	382_L	1.116	1.00
553_A	560_Q	1.115	1.00
212_V	230_L	1.112	1.00
294_L	389_K	1.111	1.00
639_N	697_L	1.109	1.00
322_F	388_M	1.106	1.00
232_A	235_K	1.101	1.00
290_M	294_L	1.097	1.00
234_V	271_L	1.096	1.00
452_C	478_V	1.094	1.00
215_I	243_I	1.093	1.00
213_I	290_M	1.092	1.00
212_V	233_L	1.091	1.00
81_Q	103_L	1.088	1.00
716_Y	755_L	1.085	1.00
211_L	358_A	1.085	1.00
675_F	706_R	1.082	1.00
138_L	562_A	1.080	1.00
331_N	336_D	1.078	1.00
214_C	217_H	1.077	1.00
290_M	385_L	1.074	1.00
338_E	341_S	1.067	1.00
458_A	487_V	1.066	1.00
560_Q	565_Q	1.066	1.00
576_D	581_R	1.063	1.00
107_G	661_D	1.058	1.00
478_V	482_Q	1.055	1.00
289_G	348_I	1.054	1.00
239_K	273_S	1.054	1.00
640_S	754_E	1.053	1.00
206_F	362_I	1.051	1.00
355_Y	363_I	1.048	1.00
325_L	388_M	1.046	1.00
560_Q	571_E	1.041	1.00
110_T	544_A	1.038	1.00
507_L	554_V	1.033	1.00
188_V	742_L	1.019	1.00
694_L	718_M	1.019	1.00
363_I	386_L	1.019	1.00
338_E	346_T	1.018	1.00
145_N	439_A	1.018	1.00
337_I	341_S	1.017	1.00
141_Y	485_L	1.017	1.00
241_I	354_A	1.014	1.00
516_D	536_A	1.014	1.00
243_I	351_L	1.011	1.00
323_D	326_R	1.009	1.00
569_A	572_Y	1.007	1.00
674_V	755_L	1.007	1.00
718_M	731_N	1.006	1.00
617_T	623_N	1.005	1.00
676_M	686_V	1.002	1.00
141_Y	484_D	1.002	1.00
644_M	753_V	0.999	1.00
447_S	456_A	0.996	1.00
641_K	754_E	0.995	1.00
387_L	622_A	0.990	1.00
134_I	485_L	0.989	1.00
243_I	276_Y	0.988	1.00
446_A	449_Q	0.985	1.00
211_L	361_T	0.984	1.00
676_M	681_A	0.976	1.00
110_T	124_P	0.976	1.00
147_V	170_Y	0.973	1.00
137_R	141_Y	0.972	1.00
662_D	665_R	0.970	1.00
128_Q	561_A	0.970	1.00
467_A	473_R	0.969	1.00
640_S	696_A	0.968	1.00
460_I	558_I	0.964	1.00
336_D	340_I	0.963	1.00
103_L	541_L	0.963	1.00
247_Q	270_Q	0.962	1.00
349_A	353_D	0.961	1.00
77_V	82_V	0.961	1.00
74_A	513_S	0.960	1.00
293_L	352_A	0.960	1.00
289_G	293_L	0.959	1.00
320_V	621_K	0.958	1.00
467_A	477_A	0.958	1.00
135_G	562_A	0.958	1.00
122_Y	506_I	0.957	1.00
142_S	146_Q	0.956	1.00
210_D	236_R	0.955	1.00
138_L	170_Y	0.954	1.00
678_A	682_K	0.953	1.00
421_S	424_F	0.952	1.00
449_Q	453_T	0.951	1.00
509_V	554_V	0.950	1.00
131_F	558_I	0.948	1.00
292_R	329_V	0.947	1.00
134_I	558_I	0.947	1.00
127_W	507_L	0.947	1.00
361_T	391_N	0.946	1.00
131_F	553_A	0.945	1.00
461_C	496_S	0.945	1.00
574_V	578_D	0.945	1.00
287_L	381_Q	0.943	1.00
694_L	753_V	0.943	1.00
645_A	715_I	0.943	1.00
446_A	450_A	0.943	1.00
239_K	274_A	0.943	1.00
75_W	83_N	0.942	1.00
319_T	387_L	0.941	1.00
284_M	378_N	0.939	1.00
570_W	576_D	0.938	1.00
145_N	173_N	0.935	1.00
343_L	348_I	0.933	1.00
534_I	594_Y	0.933	1.00
450_A	455_Q	0.931	1.00
292_R	333_E	0.931	1.00
333_E	337_I	0.927	1.00
117_A	120_D	0.927	1.00
245_P	277_N	0.926	1.00
350_E	353_D	0.925	1.00
288_K	328_D	0.925	1.00
135_G	139_Q	0.925	1.00
123_K	129_Q	0.921	1.00
513_S	540_V	0.921	1.00
637_A	752_P	0.921	1.00
430_E	433_G	0.919	1.00
459_L	483_L	0.919	1.00
193_S	380_Q	0.918	1.00
288_K	332_S	0.918	1.00
114_K	129_Q	0.915	1.00
325_L	329_V	0.915	1.00
642_L	755_L	0.914	1.00
127_W	554_V	0.909	0.99
334_W	349_A	0.908	0.99
109_L	506_I	0.907	0.99
590_E	594_Y	0.907	0.99
545_G	548_L	0.906	0.99
310_L	388_M	0.906	0.99
360_R	394_K	0.905	0.99
297_R	308_S	0.903	0.99
575_E	578_D	0.903	0.99
677_S	707_R	0.901	0.99
84_A	111_Q	0.898	0.99
614_R	620_G	0.896	0.99
581_R	585_E	0.896	0.99
134_I	137_R	0.896	0.99
597_R	601_P	0.893	0.99
677_S	711_L	0.893	0.99
732_H	735_T	0.888	0.99
243_I	278_V	0.887	0.99
279_R	712_K	0.887	0.99
207_E	229_S	0.887	0.99
675_F	710_R	0.886	0.99
384_N	624_F	0.885	0.99
80_K	104_E	0.883	0.99
278_V	286_L	0.880	0.99
138_L	460_I	0.880	0.99
712_K	715_I	0.878	0.99
429_G	434_F	0.878	0.99
442_H	450_A	0.873	0.99
634_P	698_T	0.873	0.99
636_S	752_P	0.872	0.99
328_D	331_N	0.872	0.99
465_N	655_T	0.870	0.99
439_A	442_H	0.870	0.99
214_C	240_M	0.868	0.99
596_Q	600_H	0.867	0.99
510_L	543_P	0.867	0.99
570_W	573_L	0.866	0.99
219_P	230_L	0.864	0.99
576_D	580_I	0.863	0.99
444_A	448_M	0.859	0.99
500_T	506_I	0.857	0.99
701_G	734_L	0.856	0.99
360_R	397_A	0.856	0.99
637_A	641_K	0.856	0.99
369_I	378_N	0.855	0.99
325_L	624_F	0.854	0.99
211_L	239_K	0.854	0.99
474_E	478_V	0.849	0.99
467_A	480_L	0.846	0.99
353_D	356_A	0.845	0.99
452_C	482_Q	0.845	0.99
280_I	715_I	0.844	0.99
593_D	598_I	0.835	0.99
343_L	347_Q	0.834	0.99
207_E	232_A	0.834	0.99
112_P	126_S	0.834	0.99
311_D	394_K	0.832	0.99
681_A	686_V	0.832	0.99
270_Q	710_R	0.832	0.99
451_I	454_G	0.830	0.99
150_Y	153_G	0.829	0.99
213_I	363_I	0.828	0.99
241_I	274_A	0.828	0.99
127_W	549_K	0.826	0.99
247_Q	277_N	0.824	0.99
234_V	240_M	0.821	0.99
604_F	608_N	0.821	0.99
334_W	337_I	0.820	0.99
111_Q	126_S	0.819	0.99
323_D	327_R	0.818	0.99
293_L	345_Q	0.818	0.99
233_L	236_R	0.817	0.99
59_H	540_V	0.816	0.99
698_T	751_I	0.815	0.99
286_L	290_M	0.813	0.99
63_F	70_A	0.812	0.99
679_K	709_D	0.812	0.99
91_T	121_C	0.811	0.99
145_N	172_S	0.811	0.99
345_Q	348_I	0.810	0.99
291_M	385_L	0.810	0.99
136_A	139_Q	0.810	0.99
334_W	338_E	0.808	0.99
192_A	380_Q	0.807	0.99
287_L	385_L	0.807	0.99
232_A	236_R	0.806	0.99
277_N	712_K	0.803	0.99
577_Y	580_I	0.803	0.99
137_R	485_L	0.802	0.99
346_T	350_E	0.802	0.99
244_N	248_E	0.799	0.99
363_I	382_L	0.799	0.99
637_A	640_S	0.799	0.99
429_G	436_P	0.798	0.99
74_A	540_V	0.797	0.99
297_R	356_A	0.796	0.99
354_A	358_A	0.796	0.99
437_P	441_G	0.795	0.99
541_L	544_A	0.795	0.99
285_A	289_G	0.793	0.99
133_E	136_A	0.793	0.99
166_F	555_V	0.792	0.99
367_M	371_Q	0.792	0.99
289_G	339_R	0.791	0.99
231_R	234_V	0.789	0.99
247_Q	710_R	0.786	0.99
294_L	385_L	0.786	0.99
679_K	683_I	0.785	0.99
211_L	355_Y	0.782	0.98
451_I	483_L	0.782	0.98
141_Y	457_R	0.780	0.98
279_R	342_G	0.778	0.98
490_A	506_I	0.778	0.98
623_N	626_T	0.775	0.98
594_Y	598_I	0.775	0.98
288_K	329_V	0.775	0.98
591_F	595_N	0.775	0.98
247_Q	709_D	0.774	0.98
72_A	90_N	0.770	0.98
427_R	431_R	0.769	0.98
201_V	205_D	0.769	0.98
119_S	123_K	0.768	0.98
278_V	341_S	0.767	0.98
747_G	750_S	0.766	0.98
296_E	334_W	0.766	0.98
68_N	225_R	0.766	0.98
457_R	483_L	0.764	0.98
604_F	607_I	0.763	0.98
607_I	610_A	0.762	0.98
166_F	558_I	0.762	0.98
591_F	594_Y	0.762	0.98
579_R	583_D	0.760	0.98
536_A	599_R	0.758	0.98
703_R	731_N	0.758	0.98
334_W	345_Q	0.757	0.98
289_G	336_D	0.754	0.98
139_Q	562_A	0.754	0.98
549_K	554_V	0.753	0.98
125_L	130_A	0.752	0.98
481_T	502_R	0.751	0.98
294_L	308_S	0.751	0.98
538_R	599_R	0.750	0.98
220_G	268_E	0.749	0.98
77_V	80_K	0.749	0.98
192_A	742_L	0.749	0.98
592_A	595_N	0.749	0.98
347_Q	354_A	0.748	0.98
131_F	135_G	0.746	0.98
104_E	541_L	0.746	0.98
461_C	488_H	0.746	0.98
516_D	538_R	0.744	0.98
338_E	343_L	0.742	0.98
289_G	334_W	0.742	0.98
276_Y	286_L	0.742	0.98
189_G	383_V	0.739	0.98
676_M	692_V	0.739	0.98
151_T	154_R	0.739	0.98
335_K	338_E	0.737	0.98
155_T	462_M	0.736	0.98
494_N	500_T	0.736	0.98
328_D	332_S	0.735	0.98
360_R	395_P	0.735	0.98
110_T	113_L	0.735	0.98
474_E	477_A	0.735	0.98
205_D	396_G	0.735	0.98
166_F	559_A	0.734	0.98
103_L	511_G	0.734	0.98
698_T	735_T	0.733	0.98
739_H	744_G	0.733	0.98
700_D	703_R	0.731	0.98
556_A	560_Q	0.731	0.98
511_G	544_A	0.730	0.98
352_A	356_A	0.729	0.98
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656_T	660_M	0.727	0.98
597_R	600_H	0.727	0.98
373_E	747_G	0.726	0.98
193_S	625_I	0.725	0.98
608_N	611_A	0.724	0.98
676_M	707_R	0.724	0.98
697_L	752_P	0.724	0.98
248_E	268_E	0.723	0.97
516_D	574_V	0.721	0.97
581_R	584_I	0.720	0.97
458_A	505_Y	0.719	0.97
686_V	707_R	0.718	0.97
315_I	319_T	0.718	0.97
284_M	381_Q	0.718	0.97
91_T	94_S	0.718	0.97
134_I	460_I	0.717	0.97
441_G	445_I	0.716	0.97
105_A	492_K	0.714	0.97
148_E	459_L	0.712	0.97
104_E	544_A	0.712	0.97
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731_N	734_L	0.710	0.97
429_G	432_Y	0.709	0.97
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142_S	484_D	0.708	0.97
188_V	376_T	0.707	0.97
239_K	357_A	0.706	0.97
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577_Y	584_I	0.704	0.97
576_D	579_R	0.704	0.97
214_C	268_E	0.703	0.97
427_R	430_E	0.703	0.97
79_D	542_K	0.702	0.97
429_G	433_G	0.702	0.97
269_T	275_Y	0.701	0.97
156_S	159_A	0.700	0.97
66_C	70_A	0.700	0.97
289_G	333_E	0.700	0.97
131_F	134_I	0.699	0.97
672_D	722_S	0.697	0.97
318_H	613_R	0.696	0.97
247_Q	275_Y	0.694	0.97
62_S	535_H	0.693	0.97
586_A	590_E	0.693	0.97
443_A	744_G	0.693	0.97
115_Y	120_D	0.691	0.97
63_F	66_C	0.690	0.97
128_Q	549_K	0.690	0.97
415_G	418_E	0.689	0.97
432_Y	435_T	0.684	0.96
340_I	629_G	0.684	0.96
128_Q	132_D	0.684	0.96
190_L	383_V	0.683	0.96
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445_I	448_M	0.682	0.96
586_A	589_P	0.682	0.96
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322_F	624_F	0.671	0.96
580_I	584_I	0.671	0.96
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246_L	675_F	0.667	0.96
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113_L	493_L	0.664	0.96
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480_L	486_A	0.656	0.96
351_L	354_A	0.655	0.96
386_L	399_I	0.653	0.95
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605_H	611_A	0.652	0.95
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640_S	697_L	0.648	0.95
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170_Y	562_A	0.648	0.95
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738_N	747_G	0.646	0.95
465_N	496_S	0.646	0.95
585_E	589_P	0.645	0.95
587_V	590_E	0.645	0.95
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288_K	381_Q	0.644	0.95
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731_N	735_T	0.640	0.95
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649_S	673_V	0.639	0.95
514_E	544_A	0.639	0.95
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595_N	599_R	0.638	0.95
502_R	506_I	0.634	0.95
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294_L	388_M	0.634	0.95
698_T	752_P	0.634	0.95
284_M	374_H	0.634	0.95
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618_P	623_N	0.633	0.95
289_G	338_E	0.632	0.95
324_E	625_I	0.632	0.95
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490_A	494_N	0.631	0.95
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539_G	543_P	0.629	0.94
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387_L	624_F	0.628	0.94
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510_L	515_I	0.627	0.94
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286_L	343_L	0.625	0.94
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355_Y	385_L	0.623	0.94
296_E	326_R	0.622	0.94
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552_C	556_A	0.618	0.94
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533_M	605_H	0.615	0.94
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460_I	487_V	0.612	0.94
246_L	717_P	0.611	0.94
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359_E	394_K	0.610	0.93
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113_L	122_Y	0.609	0.93
229_S	232_A	0.609	0.93
170_Y	564_P	0.609	0.93
603_G	607_I	0.608	0.93
111_Q	125_L	0.608	0.93
373_E	738_N	0.607	0.93
447_S	451_I	0.607	0.93
473_R	730_S	0.607	0.93
79_D	82_V	0.606	0.93
141_Y	147_V	0.604	0.93
183_H	187_S	0.604	0.93
70_A	94_S	0.604	0.93
593_D	600_H	0.603	0.93
480_L	502_R	0.601	0.93
122_Y	125_L	0.600	0.93
511_G	541_L	0.599	0.93
289_G	352_A	0.598	0.93
289_G	345_Q	0.597	0.93
155_T	159_A	0.597	0.93
292_R	337_I	0.597	0.93
217_H	402_L	0.597	0.93
112_P	554_V	0.597	0.93
407_N	410_G	0.596	0.93
89_E	228_T	0.595	0.93
92_V	650_H	0.595	0.93
138_L	147_V	0.594	0.93
167_A	175_F	0.594	0.93
314_F	318_H	0.594	0.93
406_S	409_Q	0.593	0.93
328_D	626_T	0.593	0.93
514_E	548_L	0.593	0.93
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607_I	611_A	0.592	0.92
285_A	336_D	0.592	0.92
601_P	604_F	0.592	0.92
559_A	562_A	0.591	0.92
580_I	583_D	0.589	0.92
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372_H	750_S	0.589	0.92
57_P	76_E	0.588	0.92
81_Q	98_W	0.587	0.92
449_Q	452_C	0.587	0.92
239_K	350_E	0.586	0.92
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711_L	715_I	0.586	0.92
369_I	379_V	0.585	0.92
114_K	503_H	0.584	0.92
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314_F	319_T	0.583	0.92
736_L	751_I	0.583	0.92
466_F	496_S	0.583	0.92
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469_A	655_T	0.581	0.92
130_A	507_L	0.581	0.92
84_A	88_A	0.579	0.92
311_D	314_F	0.579	0.92
365_Y	399_I	0.579	0.92
644_M	718_M	0.578	0.92
598_I	602_G	0.578	0.92
663_R	667_V	0.576	0.91
426_A	429_G	0.576	0.91
218_N	244_N	0.576	0.91
572_Y	577_Y	0.576	0.91
577_Y	583_D	0.576	0.91
376_T	742_L	0.575	0.91
439_A	444_A	0.575	0.91
319_T	322_F	0.575	0.91
280_I	645_A	0.575	0.91
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664_Y	667_V	0.573	0.91
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282_G	285_A	0.570	0.91
310_L	326_R	0.570	0.91
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460_I	555_V	0.567	0.91
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360_R	391_N	0.565	0.91
416_I	419_K	0.564	0.91
346_T	353_D	0.564	0.91
410_G	413_T	0.564	0.91
316_Q	323_D	0.563	0.90
344_S	349_A	0.563	0.90
378_N	382_L	0.563	0.90
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320_V	324_E	0.559	0.90
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475_A	737_D	0.558	0.90
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493_L	501_A	0.555	0.90
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150_Y	154_R	0.552	0.90
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707_R	710_R	0.551	0.90
445_I	450_A	0.550	0.89
437_P	440_P	0.550	0.89
144_P	171_G	0.550	0.89
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375_G	379_V	0.549	0.89
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215_I	385_L	0.549	0.89
577_Y	585_E	0.549	0.89
602_G	605_H	0.548	0.89
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295_I	308_S	0.547	0.89
426_A	433_G	0.547	0.89
277_N	347_Q	0.546	0.89
588_L	592_A	0.546	0.89
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294_L	355_Y	0.546	0.89
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240_M	271_L	0.545	0.89
134_I	138_L	0.545	0.89
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423_E	427_R	0.543	0.89
491_T	509_V	0.543	0.89
677_S	684_C	0.542	0.89
642_L	677_S	0.541	0.89
103_L	513_S	0.541	0.89
128_Q	557_G	0.540	0.89
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448_M	451_I	0.538	0.88
473_R	477_A	0.538	0.88
446_A	744_G	0.538	0.88
61_A	72_A	0.537	0.88
291_M	295_I	0.536	0.88
643_V	750_S	0.536	0.88
347_Q	351_L	0.534	0.88
477_A	502_R	0.534	0.88
593_D	597_R	0.534	0.88
736_L	747_G	0.534	0.88
691_R	705_S	0.534	0.88
488_H	496_S	0.533	0.88
162_L	570_W	0.533	0.88
245_P	278_V	0.533	0.88
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438_H	441_G	0.533	0.88
246_L	647_V	0.533	0.88
543_P	548_L	0.532	0.88
596_Q	599_R	0.532	0.88
290_M	353_D	0.532	0.88
568_V	572_Y	0.531	0.88
292_R	336_D	0.531	0.88
183_H	186_T	0.530	0.88
294_L	309_L	0.530	0.88
579_R	582_N	0.530	0.88
619_S	626_T	0.530	0.88
573_L	577_Y	0.530	0.88
450_A	456_A	0.529	0.88
449_Q	737_D	0.529	0.88
428_L	432_Y	0.529	0.88
123_K	133_E	0.529	0.88
577_Y	582_N	0.528	0.87
217_H	366_G	0.528	0.87
96_L	99_G	0.528	0.87
176_P	180_N	0.527	0.87
678_A	707_R	0.526	0.87
355_Y	391_N	0.526	0.87
690_E	705_S	0.525	0.87
135_G	557_G	0.525	0.87
701_G	731_N	0.525	0.87
99_G	663_R	0.524	0.87
603_G	606_L	0.523	0.87
231_R	235_K	0.523	0.87
606_L	610_A	0.523	0.87
135_G	558_I	0.522	0.87
215_I	369_I	0.522	0.87
167_A	170_Y	0.521	0.87
213_I	355_Y	0.520	0.87
244_N	275_Y	0.518	0.86
576_D	585_E	0.517	0.86
587_V	592_A	0.517	0.86
159_A	515_I	0.517	0.86
204_E	208_K	0.515	0.86
130_A	134_I	0.515	0.86
559_A	565_Q	0.515	0.86
431_R	587_V	0.515	0.86
509_V	551_E	0.515	0.86
294_L	357_A	0.515	0.86
129_Q	132_D	0.515	0.86
634_P	751_I	0.515	0.86
648_R	720_D	0.515	0.86
125_L	485_L	0.514	0.86
597_R	608_N	0.513	0.86
486_A	496_S	0.513	0.86
391_N	394_K	0.513	0.86
427_R	433_G	0.513	0.86
120_D	123_K	0.513	0.86
63_F	91_T	0.512	0.86
343_L	351_L	0.512	0.86
431_R	586_A	0.511	0.86
487_V	505_Y	0.510	0.86
290_M	361_T	0.510	0.86
94_S	98_W	0.510	0.86
662_D	666_G	0.509	0.86
431_R	434_F	0.509	0.86
288_K	325_L	0.509	0.86
459_L	467_A	0.509	0.86
331_N	628_K	0.509	0.86
680_Q	684_C	0.508	0.85
641_K	684_C	0.508	0.85
711_L	714_V	0.508	0.85
206_F	226_M	0.508	0.85
696_A	752_P	0.508	0.85
290_M	293_L	0.508	0.85
92_V	96_L	0.508	0.85
87_F	95_L	0.507	0.85
290_M	356_A	0.506	0.85
528_E	534_I	0.506	0.85
641_K	697_L	0.505	0.85
138_L	166_F	0.505	0.85
467_A	496_S	0.505	0.85
202_L	205_D	0.504	0.85
461_C	480_L	0.503	0.85
231_R	271_L	0.503	0.85
556_A	576_D	0.502	0.85
393_G	398_G	0.502	0.85
219_P	402_L	0.501	0.85
374_H	378_N	0.501	0.85
282_G	337_I	0.500	0.85
267_S	270_Q	0.500	0.85

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1h0hA	1	0.8814	100	0.235	Contact Map
2iv2X	1	0.834	100	0.235	Contact Map
1kqfA	3	0.8788	100	0.238	Contact Map
2napA	1	0.863	100	0.243	Contact Map
2e7zA	1	0.8485	100	0.244	Contact Map
2vpzA	1	0.8577	100	0.247	Contact Map
3ml1A	1	0.8709	100	0.25	Contact Map
2ivfA	1	0.8709	100	0.272	Contact Map
1q16A	2	0.9223	100	0.277	Contact Map
1g8kA	3	0.8379	100	0.292	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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