GREMLIN Database
YAHJ - Uncharacterized protein YahJ
UniProt: P77554 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13594
Length: 460 (381)
Sequences: 19955 (15359)
Seq/√Len: 786.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
448_F453_L4.8961.00
111_K445_T3.8431.00
85_Q90_V3.7761.00
446_A453_L3.7571.00
56_L108_A3.4951.00
423_D450_K3.2361.00
57_D105_H3.1731.00
419_K422_D3.1711.00
108_A428_L3.1211.00
348_K352_D3.1171.00
394_N397_R2.9701.00
116_T179_T2.8971.00
59_V108_A2.8291.00
114_L429_V2.6511.00
91_A420_A2.6161.00
318_Q353_K2.5581.00
400_F404_G2.5481.00
356_K408_P2.4361.00
114_L427_V2.3541.00
87_G423_D2.2751.00
88_K423_D2.2621.00
412_K416_V2.2331.00
113_M428_L2.1881.00
55_Y83_E2.1551.00
453_L456_G2.1111.00
104_P456_G2.1021.00
426_F448_F2.0961.00
174_Q454_V2.0741.00
158_L161_Y2.0291.00
346_P349_Q2.0171.00
264_I267_D2.0121.00
82_V113_M1.9831.00
87_G450_K1.9731.00
84_I426_F1.9721.00
82_V418_P1.9721.00
54_Y448_F1.9491.00
230_L233_E1.9021.00
58_N107_D1.9021.00
81_T96_K1.9001.00
400_F405_D1.8811.00
233_E237_A1.8611.00
318_Q322_E1.8611.00
418_P426_F1.8471.00
415_R423_D1.8401.00
351_H397_R1.8221.00
230_L234_A1.8141.00
430_D445_T1.8141.00
93_R96_K1.8061.00
317_E353_K1.7971.00
92_L420_A1.7951.00
77_T80_Q1.7901.00
88_K415_R1.7891.00
397_R400_F1.7741.00
111_K430_D1.7601.00
263_Q267_D1.7571.00
447_T455_W1.7451.00
83_E91_A1.7301.00
408_P413_G1.7091.00
163_Q201_A1.7071.00
113_M426_F1.7021.00
295_E323_L1.6991.00
230_L235_M1.6861.00
314_T349_Q1.6821.00
83_E103_L1.6811.00
427_V444_R1.6591.00
61_L80_Q1.6461.00
111_K428_L1.6211.00
175_S455_W1.6161.00
449_H454_V1.6071.00
446_A456_G1.6071.00
358_M409_L1.5991.00
82_V426_F1.5941.00
416_V423_D1.5521.00
405_D408_P1.5381.00
350_L355_V1.5281.00
255_E259_D1.5251.00
292_E296_K1.5201.00
284_V288_N1.5181.00
57_D81_T1.5021.00
89_I418_P1.4891.00
163_Q205_R1.4671.00
417_W422_D1.4621.00
326_R356_K1.4591.00
56_L84_I1.4471.00
83_E90_V1.4431.00
118_R406_V1.4421.00
380_A402_A1.4411.00
114_L117_T1.4411.00
59_V113_M1.4381.00
232_R236_Q1.4361.00
326_R409_L1.4291.00
233_E236_Q1.4261.00
259_D263_Q1.4201.00
61_L82_V1.4141.00
428_L446_A1.4031.00
265_A272_V1.3991.00
114_L399_L1.3721.00
81_T98_H1.3721.00
349_Q353_K1.3691.00
384_A398_S1.3641.00
120_M358_M1.3521.00
432_S435_A1.3481.00
264_I268_Y1.3451.00
388_I393_Q1.3351.00
84_I448_F1.3281.00
91_A98_H1.3171.00
404_G422_D1.3171.00
198_N201_A1.3161.00
428_L448_F1.3121.00
108_A113_M1.3051.00
231_M235_M1.3021.00
80_Q94_E1.2991.00
241_Y244_G1.2911.00
167_E205_R1.2841.00
414_E422_D1.2831.00
173_L181_A1.2821.00
56_L448_F1.2811.00
319_Q323_L1.2771.00
56_L426_F1.2721.00
231_M234_A1.2721.00
412_K415_R1.2681.00
229_P233_E1.2611.00
404_G408_P1.2561.00
260_T263_Q1.2521.00
246_D249_S1.2491.00
239_A243_G1.2471.00
201_A205_R1.2441.00
229_P232_R1.2371.00
439_A442_S1.2291.00
314_T346_P1.2271.00
240_H243_G1.2251.00
81_T95_N1.2191.00
349_Q352_D1.2141.00
120_M406_V1.2111.00
238_G241_Y1.2031.00
254_M257_S1.2031.00
434_S437_A1.2001.00
281_P285_A1.1991.00
58_N79_R1.1961.00
55_Y81_T1.1841.00
358_M405_D1.1831.00
91_A97_L1.1801.00
182_R410_N1.1801.00
271_G411_E1.1781.00
234_A237_A1.1731.00
197_Q201_A1.1721.00
285_A288_N1.1701.00
321_D355_V1.1681.00
356_K405_D1.1621.00
54_Y84_I1.1611.00
330_Q333_S1.1441.00
256_K259_D1.1291.00
170_I174_Q1.1241.00
359_T383_Y1.1231.00
120_M328_V1.1181.00
429_V444_R1.1171.00
432_S436_E1.1161.00
306_I309_A1.1121.00
159_Q201_A1.1091.00
273_D307_S1.1071.00
180_I416_V1.1031.00
381_N385_Q1.1031.00
319_Q322_E1.1011.00
242_V245_L1.0961.00
94_E97_L1.0861.00
313_A316_N1.0831.00
309_A327_M1.0801.00
60_L78_A1.0801.00
147_M150_L1.0791.00
293_T296_K1.0761.00
280_T284_V1.0761.00
58_N110_G1.0751.00
146_D150_L1.0731.00
167_E171_D1.0661.00
431_A436_E1.0601.00
174_Q449_H1.0591.00
380_A398_S1.0471.00
315_L318_Q1.0451.00
172_L175_S1.0391.00
80_Q92_L1.0341.00
433_C436_E1.0271.00
106_Y446_A1.0221.00
76_R396_S1.0221.00
328_V358_M1.0211.00
213_E217_F1.0161.00
312_L350_L1.0141.00
375_D378_E1.0121.00
214_I217_F1.0111.00
60_L77_T1.0091.00
208_A211_E1.0081.00
230_L237_A1.0051.00
171_D206_R1.0031.00
104_P453_L1.0031.00
124_L169_L1.0001.00
232_R268_Y0.9991.00
80_Q93_R0.9991.00
247_P250_V0.9991.00
106_Y448_F0.9981.00
208_A213_E0.9971.00
241_Y245_L0.9951.00
239_A242_V0.9941.00
96_K99_P0.9931.00
320_V327_M0.9911.00
285_A289_Y0.9891.00
54_Y104_P0.9881.00
427_V447_T0.9871.00
118_R180_I0.9871.00
378_E381_N0.9821.00
93_R97_L0.9771.00
80_Q95_N0.9771.00
81_T97_L0.9731.00
309_A312_L0.9711.00
159_Q163_Q0.9701.00
413_G422_D0.9691.00
202_V205_R0.9631.00
89_I426_F0.9591.00
276_L306_I0.9591.00
73_V76_R0.9571.00
58_N109_G0.9571.00
232_R237_A0.9561.00
358_M406_V0.9481.00
321_D353_K0.9431.00
83_E102_T0.9371.00
60_L112_L0.9361.00
90_V420_A0.9311.00
56_L106_Y0.9231.00
291_V295_E0.9191.00
93_R98_H0.9191.00
359_T401_L0.9171.00
118_R416_V0.9161.00
334_I337_T0.9151.00
340_I345_M0.9151.00
163_Q167_E0.9141.00
401_L405_D0.9061.00
307_S310_F0.9061.00
246_D251_D0.9041.00
62_E112_L0.9031.00
238_G243_G0.8991.00
275_H362_D0.8981.00
259_D292_E0.8961.00
56_L113_M0.8931.00
221_G224_L0.8901.00
320_V324_A0.8861.00
318_Q321_D0.8841.00
178_T376_M0.8801.00
232_R235_M0.8731.00
54_Y106_Y0.8681.00
332_I382_L0.8651.00
230_L236_Q0.8651.00
118_R410_N0.8631.00
327_M355_V0.8631.00
291_V319_Q0.8631.00
151_E155_L0.8591.00
209_G213_E0.8581.00
341_G345_M0.8551.00
195_N198_N0.8551.00
292_E295_E0.8541.00
258_L274_I0.8541.00
82_V92_L0.8531.00
377_L380_A0.8531.00
377_L429_V0.8501.00
348_K351_H0.8461.00
102_T105_H0.8401.00
329_V333_S0.8401.00
213_E216_A0.8391.00
208_A212_C0.8391.00
247_P251_D0.8381.00
174_Q447_T0.8351.00
414_E417_W0.8291.00
257_S260_T0.8291.00
63_T73_V0.8291.00
57_D107_D0.8281.00
341_G344_H0.8271.00
74_Q400_F0.8241.00
111_K446_A0.8231.00
194_K198_N0.8211.00
195_N202_V0.8191.00
314_T353_K0.8171.00
269_D303_K0.8131.00
143_T146_D0.8131.00
81_T91_A0.8131.00
198_N202_V0.8131.00
340_I343_L0.8131.00
444_R447_T0.8111.00
295_E319_Q0.8101.00
433_C438_V0.8051.00
232_R264_I0.8001.00
118_R407_L0.7991.00
239_A245_L0.7971.00
339_P345_M0.7961.00
265_A270_K0.7961.00
57_D95_N0.7941.00
180_I412_K0.7931.00
238_G242_V0.7931.00
320_V323_L0.7911.00
348_K397_R0.7911.00
320_V325_N0.7911.00
430_D443_P0.7901.00
328_V333_S0.7881.00
388_I392_E0.7881.00
238_G245_L0.7871.00
174_Q455_W0.7871.00
431_A438_V0.7871.00
171_D175_S0.7851.00
314_T318_Q0.7811.00
381_N440_R0.7781.00
294_V298_P0.7781.00
193_L197_Q0.7741.00
123_H275_H0.7741.00
340_I344_H0.7711.00
290_M294_V0.7661.00
317_E350_L0.7661.00
95_N99_P0.7661.00
83_E93_R0.7641.00
204_A207_Q0.7601.00
201_A204_A0.7571.00
203_L210_F0.7521.00
416_V422_D0.7501.00
180_I410_N0.7491.00
306_I320_V0.7491.00
288_N319_Q0.7461.00
399_L403_T0.7461.00
194_K197_Q0.7461.00
79_R92_L0.7461.00
309_A320_V0.7451.00
408_P417_W0.7421.00
262_F272_V0.7411.00
173_L374_G0.7401.00
196_L199_L0.7391.00
149_K152_Q0.7371.00
425_S450_K0.7371.00
119_D122_I0.7361.00
153_K156_P0.7341.00
387_Y391_N0.7331.00
179_T447_T0.7321.00
240_H244_G0.7301.00
203_L207_Q0.7291.00
308_H362_D0.7281.00
184_H273_D0.7271.00
413_G416_V0.7261.00
435_A438_V0.7251.00
95_N98_H0.7241.00
262_F266_L0.7241.00
123_H308_H0.7241.00
326_R358_M0.7221.00
121_H362_D0.7211.00
203_L206_R0.7161.00
257_S261_M0.7161.00
108_A111_K0.7161.00
79_R109_G0.7151.00
305_T409_L0.7051.00
172_L176_K0.7051.00
293_T297_T0.7051.00
211_E214_I0.7041.00
339_P344_H0.7031.00
79_R95_N0.7031.00
60_L79_R0.7031.00
388_I391_N0.7021.00
330_Q360_G0.7011.00
284_V316_N0.7001.00
431_A442_S0.6991.00
402_A406_V0.6981.00
220_H223_L0.6981.00
266_L304_L0.6971.00
91_A101_A0.6961.00
303_K408_P0.6961.00
286_A289_Y0.6951.00
256_K260_T0.6921.00
123_H362_D0.6911.00
378_E382_L0.6901.00
342_T345_M0.6891.00
274_I290_M0.6891.00
173_L178_T0.6871.00
373_L378_E0.6861.00
195_N199_L0.6841.00
124_L181_A0.6821.00
317_E349_Q0.6821.00
376_M402_A0.6811.00
308_H312_L0.6781.00
206_R209_G0.6781.00
325_N328_V0.6771.00
223_L226_K0.6751.00
440_R443_P0.6751.00
163_Q198_N0.6731.00
99_P105_H0.6711.00
119_D361_T0.6711.00
117_T377_L0.6711.00
332_I379_K0.6701.00
197_Q200_Q0.6701.00
321_D324_A0.6701.00
84_I90_V0.6681.00
117_T178_T0.6681.00
431_A434_S0.6671.00
216_A219_Q0.6671.00
73_V77_T0.6651.00
168_K172_L0.6641.00
59_V426_F0.6631.00
328_V332_I0.6631.00
389_R393_Q0.6621.00
202_V206_R0.6621.00
82_V89_I0.6611.00
81_T93_R0.6611.00
425_S449_H0.6601.00
182_R305_T0.6601.00
170_I208_A0.6591.00
176_K375_D0.6591.00
196_L200_Q0.6571.00
116_T449_H0.6551.00
324_A356_K0.6521.00
200_Q203_L0.6511.00
122_I173_L0.6511.00
80_Q418_P0.6501.00
357_V401_L0.6481.00
320_V355_V0.6481.00
248_T251_D0.6481.00
147_M151_E0.6471.00
263_Q266_L0.6471.00
259_D293_T0.6471.00
315_L319_Q0.6461.00
286_A290_M0.6461.00
217_F220_H0.6431.00
239_A244_G0.6421.00
92_L418_P0.6421.00
209_G212_C0.6421.00
161_Y164_E0.6411.00
205_R208_A0.6391.00
72_A404_G0.6391.00
55_Y102_T0.6381.00
130_G133_W0.6381.00
168_K171_D0.6371.00
224_L227_S0.6331.00
195_N200_Q0.6311.00
382_L385_Q0.6301.00
255_E285_A0.6291.00
327_M350_L0.6251.00
331_Q334_I0.6241.00
58_N108_A0.6231.00
329_V334_I0.6221.00
79_R94_E0.6201.00
266_L301_K0.6191.00
76_R79_R0.6181.00
199_L202_V0.6171.00
63_T72_A0.6161.00
159_Q197_Q0.6161.00
228_E260_T0.6151.00
433_C437_A0.6151.00
131_G135_S0.6151.00
339_P343_L0.6141.00
260_T264_I0.6131.00
184_H307_S0.6131.00
120_M410_N0.6121.00
91_A99_P0.6121.00
160_P164_E0.6091.00
214_I218_P0.6091.00
124_L170_I0.6091.00
121_H275_H0.6091.00
128_F131_G0.6071.00
321_D354_G0.6071.00
72_A419_K0.6061.00
348_K387_Y0.6051.00
292_E315_L0.6051.00
144_I148_I0.6041.00
167_E202_V0.6031.00
89_I92_L0.6031.00
59_V428_L0.5991.00
308_H313_A0.5991.00
273_D305_T0.5981.00
434_S438_V0.5971.00
215_V218_P0.5951.00
312_L346_P0.5951.00
231_M236_Q0.5951.00
294_V302_G0.5931.00
77_T396_S0.5901.00
203_L208_A0.5901.00
145_Q149_K0.5891.00
384_A389_R0.5891.00
413_G417_W0.5881.00
180_I425_S0.5881.00
259_D296_K0.5871.00
351_H357_V0.5861.00
207_Q211_E0.5851.00
91_A96_K0.5831.00
384_A388_I0.5811.00
167_E206_R0.5791.00
220_H224_L0.5761.00
199_L203_L0.5761.00
431_A437_A0.5731.00
73_V419_K0.5731.00
330_Q334_I0.5701.00
159_Q198_N0.5701.00
213_E218_P0.5691.00
396_S400_F0.5691.00
214_I220_H0.5681.00
266_L302_G0.5681.00
106_Y453_L0.5681.00
294_V297_T0.5661.00
122_I181_A0.5661.00
203_L212_C0.5641.00
216_A220_H0.5631.00
395_L434_S0.5631.00
389_R392_E0.5591.00
62_E76_R0.5581.00
450_K453_L0.5581.00
229_P234_A0.5551.00
292_E319_Q0.5511.00
211_E215_V0.5501.00
432_S437_A0.5501.00
407_L422_D0.5491.00
375_D381_N0.5471.00
170_I181_A0.5461.00
194_K199_L0.5451.00
255_E288_N0.5431.00
210_F213_E0.5421.00
61_L78_A0.5381.00
117_T402_A0.5381.00
181_A210_F0.5381.00
305_T328_V0.5371.00
331_Q335_A0.5371.00
167_E170_I0.5371.00
153_K157_E0.5371.00
167_E207_Q0.5361.00
222_L226_K0.5351.00
332_I336_S0.5341.00
57_D99_P0.5331.00
98_H101_A0.5331.00
308_H311_A0.5331.00
232_R267_D0.5331.00
351_H405_D0.5321.00
72_A77_T0.5311.00
120_M409_L0.5311.00
126_K363_S0.5301.00
218_P221_G0.5301.00
284_V287_I0.5291.00
240_H245_L0.5281.00
291_V322_E0.5271.00
152_Q155_L0.5271.00
406_V409_L0.5261.00
359_T402_A0.5261.00
163_Q202_V0.5251.00
60_L432_S0.5251.00
210_F214_I0.5241.00
124_L183_S0.5221.00
209_G214_I0.5221.00
361_T379_K0.5211.00
304_L308_H0.5201.00
245_L248_T0.5201.00
317_E321_D0.5201.00
375_D382_L0.5161.00
84_I424_A0.5151.00
325_N331_Q0.5131.00
307_S328_V0.5111.00
345_M350_L0.5101.00
211_E412_K0.5091.00
196_L202_V0.5091.00
62_E72_A0.5091.00
295_E298_P0.5081.00
298_P302_G0.5081.00
154_M157_E0.5071.00
397_R401_L0.5071.00
229_P237_A0.5051.00
295_E322_E0.5041.00
329_V332_I0.5041.00
127_T363_S0.5031.00
377_L381_N0.5031.00
326_R408_P0.5021.00
182_R273_D0.5011.00
386_L390_P0.5011.00
117_T380_A0.5011.00
348_K391_N0.5011.00
83_E96_K0.5001.00
200_Q204_A0.5001.00
255_E293_T0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4cqbA 2 0.8348 100 0.401 Contact Map
1ra0A 4 0.8478 100 0.402 Contact Map
3lnpA 2 0.8326 100 0.403 Contact Map
3hpaA 2 0.8217 100 0.405 Contact Map
4dzhA 2 0.8391 100 0.406 Contact Map
4r85A 4 0.8413 100 0.406 Contact Map
3ls9A 2 0.8457 100 0.408 Contact Map
2pajA 2 0.7674 100 0.411 Contact Map
2oodA 2 0.837 100 0.413 Contact Map
4f0rA 2 0.8326 100 0.419 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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