GREMLIN Database
YKGF - Uncharacterized electron transport protein YkgF
UniProt: P77536 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13583
Length: 475 (454)
Sequences: 1368 (773)
Seq/√Len: 36.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
458_E466_K5.5631.00
77_V82_G4.6681.00
95_R99_Q4.5631.00
73_L291_L4.1061.00
99_Q103_R4.0331.00
98_L129_A3.9141.00
74_S78_T3.9131.00
101_A201_I3.8991.00
60_D311_R3.8681.00
53_D375_R3.5901.00
125_V129_A3.4831.00
106_A201_I3.4341.00
82_G289_F3.4201.00
201_I236_I3.3891.00
77_V291_L3.3841.00
76_K79_Q3.3581.00
77_V289_F3.1981.00
72_Q75_E3.1211.00
101_A236_I3.0871.00
104_K288_E3.0721.00
377_P380_K3.0401.00
215_S273_W3.0341.00
91_E95_R2.9091.00
97_I292_V2.8981.00
55_A257_M2.8361.00
98_L125_V2.8271.00
117_T238_V2.7831.00
104_K234_T2.7641.00
65_N68_A2.7371.00
85_Y96_Y2.6781.00
61_H69_Y2.6721.00
309_V341_I2.6691.00
146_D160_K2.6611.00
110_V136_T2.5901.00
369_D379_S2.5651.00
343_A382_I2.5571.00
148_D160_K2.5561.00
56_A311_R2.5391.00
146_D168_V2.4161.00
233_K287_E2.4051.00
458_E463_W2.3811.00
106_A236_I2.3611.00
344_V381_L2.3341.00
100_V234_T2.3321.00
82_G291_L2.3301.00
61_H65_N2.3280.99
344_V378_L2.3130.99
305_E384_R2.3010.99
241_M293_I2.2780.99
194_E198_S2.2750.99
215_S275_T2.2640.99
210_V245_A2.2490.99
209_A239_M2.2100.99
71_Y75_E2.1660.99
62_V69_Y2.1290.99
107_R200_E2.1220.99
167_R171_E2.0980.99
362_C378_L2.0970.99
88_R92_D2.0900.99
110_V199_A2.0640.99
200_E233_K2.0640.99
53_D57_Q2.0590.99
210_V251_V2.0580.99
206_C239_M2.0340.99
147_Q172_R2.0320.99
132_Q195_D2.0160.99
73_L209_A1.9790.98
49_E375_R1.9790.98
73_L77_V1.9520.98
20_D164_Q1.9470.98
85_Y290_H1.9090.98
301_V348_L1.9050.98
63_L311_R1.8700.98
103_R288_E1.8340.97
408_Y412_H1.8160.97
58_I253_V1.8010.97
163_H179_E1.7970.97
92_D95_R1.7960.97
116_V294_V1.7620.96
217_C273_W1.7570.96
112_S225_A1.7550.96
83_H288_E1.7480.96
109_V203_I1.7440.96
120_I238_V1.7320.96
319_M338_P1.7300.96
362_C382_I1.7260.96
87_A96_Y1.7170.96
247_T250_E1.7090.96
56_A308_D1.6940.96
102_Q129_A1.6830.95
204_T229_T1.6630.95
96_Y100_V1.6580.95
89_T92_D1.6380.95
101_A106_A1.6250.94
308_D381_L1.6240.94
180_T183_A1.6030.94
212_E247_T1.6010.94
127_Q147_Q1.5740.93
62_V244_I1.5710.93
343_A362_C1.5460.93
109_V131_I1.5440.93
421_M462_S1.5350.93
72_Q76_K1.5300.92
65_N69_Y1.5120.92
239_M293_I1.5060.92
74_S86_F1.4540.90
182_E186_L1.4450.90
304_S388_V1.4430.90
441_G444_S1.4430.90
26_A161_D1.4130.89
59_R243_R1.3870.88
56_A60_D1.3850.88
463_W467_H1.3840.88
238_V292_V1.3830.88
138_L188_I1.3750.88
459_S462_S1.3740.88
306_F388_V1.3610.87
440_F447_M1.3460.87
234_T288_E1.3450.86
239_M291_L1.3370.86
169_L188_I1.3350.86
34_I155_V1.3250.86
125_V128_D1.3070.85
56_A375_R1.3070.85
67_D71_Y1.3060.85
201_I234_T1.3030.85
209_A293_I1.2950.84
188_I192_I1.2860.84
98_L102_Q1.2840.84
406_F410_N1.2710.83
384_R387_R1.2640.83
97_I120_I1.2540.82
53_D56_A1.2530.82
245_A251_V1.2500.82
94_T120_I1.2480.82
141_Y191_K1.2460.82
154_V316_G1.2450.82
155_V158_I1.2310.81
427_A455_A1.2310.81
117_T203_I1.2250.81
308_D311_R1.2230.81
70_L86_F1.2190.80
17_Q23_M1.2180.80
306_F381_L1.2180.80
408_Y415_L1.2140.80
96_Y290_H1.2110.80
216_V289_F1.2100.80
303_A307_R1.2060.80
346_S355_F1.2000.79
184_M188_I1.1910.79
75_E79_Q1.1880.79
405_M408_Y1.1850.79
95_R125_V1.1770.78
22_I161_D1.1750.78
160_K168_V1.1740.78
142_I169_L1.1710.78
122_V126_L1.1660.77
409_A419_G1.1520.77
369_D375_R1.1440.76
364_L382_I1.1220.75
59_R254_L1.1070.74
94_T294_V1.1040.73
403_I406_F1.1020.73
384_R388_V1.1010.73
262_A316_G1.0910.72
217_C251_V1.0900.72
85_Y92_D1.0880.72
186_L190_Q1.0850.72
86_F293_I1.0790.72
412_H415_L1.0790.72
108_K195_D1.0750.71
73_L244_I1.0720.71
216_V237_A1.0670.71
120_I294_V1.0670.71
208_F251_V1.0620.70
116_V239_M1.0590.70
62_V65_N1.0540.70
254_L374_V1.0490.69
226_R230_T1.0480.69
97_I238_V1.0440.69
158_I316_G1.0420.69
417_K461_R1.0390.69
458_E462_S1.0360.68
101_A203_I1.0270.68
219_V255_I1.0270.68
93_A120_I1.0210.67
304_S307_R1.0190.67
173_L187_F1.0140.67
73_L76_K1.0130.67
170_H176_E1.0120.67
344_V362_C1.0120.67
463_W466_K1.0120.67
216_V239_M1.0050.66
416_W420_M1.0010.66
221_N316_G1.0010.66
169_L184_M0.9950.65
122_V203_I0.9940.65
139_G155_V0.9930.65
76_K212_E0.9930.65
220_T226_R0.9920.65
15_R19_E0.9890.65
100_V104_K0.9850.65
265_A269_G0.9790.64
17_Q20_D0.9790.64
413_P417_K0.9730.64
462_S466_K0.9720.63
106_A200_E0.9540.62
387_R391_E0.9530.62
114_S117_T0.9520.62
174_G177_G0.9520.62
124_H127_Q0.9520.62
121_G149_P0.9500.62
112_S218_L0.9480.62
138_L185_T0.9470.61
206_C209_A0.9440.61
135_E337_Y0.9380.61
188_I265_A0.9360.61
47_H50_E0.9290.60
121_G124_H0.9280.60
80_N276_G0.9260.60
99_Q292_V0.9260.60
206_C243_R0.9180.59
80_N275_T0.9180.59
178_P183_A0.9100.58
204_T235_H0.9070.58
153_V338_P0.9070.58
90_K94_T0.9070.58
73_L289_F0.9070.58
37_N338_P0.9060.58
405_M448_E0.9050.58
38_R371_V0.9040.58
238_V294_V0.8990.57
458_E467_H0.8990.57
58_I62_V0.8970.57
50_E53_D0.8960.57
460_F464_F0.8940.57
148_D168_V0.8900.57
366_T382_I0.8830.56
202_G232_P0.8830.56
100_V106_A0.8810.56
369_D377_P0.8800.56
117_T122_V0.8760.55
64_S307_R0.8730.55
166_R170_H0.8700.55
124_H128_D0.8690.55
397_K400_Q0.8670.55
98_L106_A0.8670.55
114_S238_V0.8660.55
436_T440_F0.8660.55
123_N365_C0.8660.55
134_I195_D0.8630.54
255_I271_N0.8620.54
328_I332_G0.8600.54
192_I265_A0.8600.54
154_V268_T0.8590.54
427_A430_F0.8590.54
181_P185_T0.8550.54
106_A234_T0.8500.53
204_T226_R0.8480.53
69_Y246_P0.8420.52
70_L74_S0.8340.52
170_H177_G0.8330.52
336_I346_S0.8310.52
208_F374_V0.8280.51
73_L210_V0.8250.51
67_D302_L0.8240.51
259_A271_N0.8220.51
108_K198_S0.8210.51
160_K164_Q0.8190.50
68_A72_Q0.8150.50
206_C237_A0.8130.50
65_N246_P0.8130.50
369_D380_K0.8100.50
41_M264_G0.8100.50
80_N277_P0.8090.50
248_F273_W0.8080.50
420_M459_S0.8070.49
79_Q90_K0.8050.49
143_L148_D0.8040.49
36_A40_K0.8020.49
117_T123_N0.7980.49
56_A381_L0.7970.49
134_I198_S0.7970.49
428_S455_A0.7960.48
165_I257_M0.7910.48
95_R103_R0.7910.48
321_T338_P0.7900.48
362_C366_T0.7890.48
69_Y72_Q0.7890.48
90_K120_I0.7880.48
80_N279_E0.7880.48
353_K394_I0.7840.47
27_V326_R0.7820.47
166_R179_E0.7810.47
305_E388_V0.7810.47
55_A374_V0.7810.47
39_Q43_D0.7780.47
419_G422_A0.7780.47
111_K365_C0.7760.47
346_S350_G0.7750.47
123_N265_A0.7740.47
100_V105_N0.7730.46
12_T16_Q0.7720.46
139_G221_N0.7700.46
85_Y100_V0.7690.46
20_D23_M0.7680.46
390_A395_T0.7670.46
118_E123_N0.7610.45
108_K132_Q0.7550.45
218_L274_L0.7540.45
309_V344_V0.7540.45
49_E53_D0.7490.44
424_A462_S0.7490.44
61_H247_T0.7490.44
157_A165_I0.7480.44
10_F361_A0.7480.44
206_C293_I0.7480.44
63_L66_L0.7460.44
347_P446_W0.7410.44
364_L446_W0.7410.44
307_R378_L0.7400.44
378_L382_I0.7380.43
86_F241_M0.7370.43
86_F243_R0.7310.43
165_I336_I0.7290.43
39_Q371_V0.7280.43
421_M429_W0.7280.43
400_Q404_K0.7280.43
340_P446_W0.7280.43
97_I203_I0.7270.42
162_R420_M0.7270.42
394_I402_A0.7260.42
209_A244_I0.7260.42
125_V292_V0.7220.42
226_R229_T0.7210.42
229_T274_L0.7180.42
74_S243_R0.7150.41
62_V236_I0.7140.41
421_M437_P0.7140.41
17_Q245_A0.7130.41
171_E190_Q0.7120.41
101_A234_T0.7110.41
311_R381_L0.7090.41
410_N416_W0.7090.41
419_G438_L0.7080.41
139_G265_A0.7070.41
154_V158_I0.7070.41
317_A376_I0.7040.41
9_D12_T0.7030.40
382_I385_H0.7000.40
73_L215_S0.6990.40
110_V228_C0.6990.40
89_T272_T0.6970.40
267_L271_N0.6970.40
237_A291_L0.6960.40
146_D165_I0.6940.40
206_C291_L0.6940.40
27_V327_H0.6940.40
301_V309_V0.6940.40
123_N263_V0.6910.39
139_G235_H0.6880.39
363_S370_N0.6870.39
165_I356_K0.6850.39
210_V247_T0.6850.39
286_P340_P0.6840.39
67_D299_S0.6830.39
251_V273_W0.6800.39
127_Q132_Q0.6800.39
102_Q105_N0.6790.38
404_K465_K0.6780.38
12_T36_A0.6770.38
192_I263_V0.6770.38
165_I398_A0.6770.38
93_A238_V0.6760.38
229_T237_A0.6750.38
155_V268_T0.6750.38
381_L384_R0.6730.38
350_G355_F0.6730.38
438_L444_S0.6730.38
175_Y187_F0.6730.38
326_R367_A0.6720.38
16_Q468_Q0.6710.38
70_L347_P0.6680.38
54_R105_N0.6680.38
38_R262_A0.6660.37
30_A155_V0.6660.37
154_V332_G0.6650.37
101_A125_V0.6650.37
237_A378_L0.6620.37
73_L367_A0.6610.37
391_E395_T0.6570.37
18_I24_R0.6560.37
107_R132_Q0.6560.37
33_R155_V0.6540.36
251_V254_L0.6530.36
347_P358_L0.6530.36
419_G443_I0.6520.36
111_K123_N0.6510.36
95_R105_N0.6510.36
154_V262_A0.6500.36
122_V192_I0.6490.36
83_H103_R0.6490.36
59_R367_A0.6470.36
392_K395_T0.6460.36
105_N305_E0.6450.36
170_H178_P0.6430.36
208_F254_L0.6430.36
308_D355_F0.6420.35
78_T83_H0.6420.35
171_E419_G0.6410.35
23_M164_Q0.6410.35
350_G354_D0.6410.35
18_I143_L0.6410.35
308_D441_G0.6390.35
344_V371_V0.6380.35
174_G303_A0.6380.35
99_Q102_Q0.6370.35
127_Q292_V0.6360.35
251_V399_E0.6350.35
75_E103_R0.6350.35
352_Y389_M0.6340.35
71_Y86_F0.6340.35
407_A411_S0.6330.35
112_S139_G0.6330.35
123_N196_F0.6330.35
115_M331_H0.6320.35
28_A32_Q0.6300.34
178_P191_K0.6290.34
68_A75_E0.6290.34
12_T15_R0.6290.34
276_G337_Y0.6280.34
177_G190_Q0.6270.34
255_I259_A0.6260.34
405_M409_A0.6250.34
203_I238_V0.6240.34
59_R301_V0.6220.34
443_I453_P0.6220.34
151_S331_H0.6210.34
359_P362_C0.6190.34
130_G294_V0.6190.34
306_F384_R0.6190.34
425_H428_S0.6190.34
263_V345_I0.6180.34
178_P190_Q0.6170.33
188_I331_H0.6160.33
226_R274_L0.6160.33
409_A415_L0.6140.33
213_T275_T0.6140.33
104_K233_K0.6140.33
58_I468_Q0.6140.33
100_V203_I0.6140.33
383_L387_R0.6140.33
406_F416_W0.6130.33
25_K105_N0.6130.33
204_T225_A0.6120.33
220_T272_T0.6110.33
167_R177_G0.6100.33
166_R177_G0.6100.33
38_R42_V0.6080.33
338_P378_L0.6070.33
202_G228_C0.6060.33
72_Q79_Q0.6060.33
73_L258_L0.6060.33
98_L292_V0.6050.33
135_E206_C0.6050.33
165_I184_M0.6030.32
202_G278_R0.6030.32
426_A430_F0.6030.32
437_P441_G0.6030.32
94_T122_V0.6010.32
128_D292_V0.6000.32
98_L104_K0.6000.32
30_A220_T0.5990.32
221_N265_A0.5990.32
116_V240_G0.5980.32
38_R261_S0.5970.32
344_V347_P0.5970.32
238_V365_C0.5960.32
402_A405_M0.5950.32
309_V345_I0.5940.32
377_P410_N0.5940.32
440_F444_S0.5930.32
134_I165_I0.5920.32
347_P359_P0.5910.31
213_T217_C0.5910.31
448_E467_H0.5900.31
94_T184_M0.5900.31
333_Y347_P0.5900.31
188_I345_I0.5900.31
60_D63_L0.5890.31
261_S373_P0.5890.31
104_K236_I0.5890.31
426_A437_P0.5880.31
25_K29_N0.5860.31
366_T379_S0.5850.31
203_I227_M0.5840.31
70_L299_S0.5840.31
229_T235_H0.5830.31
31_Q220_T0.5830.31
79_Q422_A0.5830.31
21_P448_E0.5830.31
16_Q409_A0.5830.31
154_V406_F0.5810.31
69_Y377_P0.5800.31
112_S220_T0.5800.31
10_F236_I0.5800.31
184_M381_L0.5800.31
16_Q462_S0.5790.31
363_S382_I0.5790.31
26_A228_C0.5780.31
165_I268_T0.5780.31
167_R170_H0.5780.31
148_D172_R0.5760.30
118_E148_D0.5760.30
185_T188_I0.5760.30
184_M341_I0.5750.30
22_I164_Q0.5750.30
300_E303_A0.5740.30
196_F227_M0.5740.30
15_R99_Q0.5730.30
115_M150_P0.5730.30
188_I263_V0.5730.30
112_S154_V0.5720.30
176_E183_A0.5720.30
71_Y74_S0.5710.30
76_K80_N0.5710.30
62_V267_L0.5710.30
353_K454_E0.5680.30
49_E52_R0.5670.30
414_G448_E0.5660.30
155_V162_R0.5660.30
100_V439_K0.5650.30
208_F333_Y0.5640.29
361_A364_L0.5640.29
59_R385_H0.5640.29
101_A131_I0.5640.29
218_L460_F0.5630.29
23_M161_D0.5620.29
412_H419_G0.5620.29
220_T286_P0.5620.29
333_Y349_L0.5610.29
153_V321_T0.5610.29
459_S467_H0.5600.29
117_T460_F0.5600.29
340_P378_L0.5590.29
95_R418_V0.5590.29
30_A37_N0.5590.29
93_A292_V0.5580.29
73_L293_I0.5580.29
142_I145_L0.5580.29
443_I452_L0.5570.29
70_L241_M0.5560.29
140_E330_G0.5550.29
362_C379_S0.5550.29
448_E466_K0.5550.29
210_V217_C0.5540.29
362_C365_C0.5530.29
169_L320_N0.5520.29
16_Q105_N0.5520.29
399_E403_I0.5520.29
61_H68_A0.5520.29
308_D407_A0.5500.28
28_A273_W0.5500.28
43_D96_Y0.5490.28
127_Q133_V0.5490.28
51_W293_I0.5480.28
62_V248_F0.5480.28
447_M452_L0.5480.28
362_C369_D0.5470.28
381_L441_G0.5470.28
75_E124_H0.5460.28
135_E228_C0.5460.28
72_Q246_P0.5450.28
240_G341_I0.5440.28
41_M260_R0.5440.28
73_L288_E0.5440.28
209_A262_A0.5430.28
310_L374_V0.5430.28
118_E265_A0.5430.28
49_E344_V0.5420.28
47_H256_T0.5420.28
302_L347_P0.5390.28
421_M459_S0.5390.28
227_M230_T0.5380.28
265_A365_C0.5360.27
32_Q326_R0.5360.27
73_L237_A0.5360.27
112_S251_V0.5350.27
184_M290_H0.5340.27
417_K465_K0.5340.27
22_I26_A0.5340.27
17_Q200_E0.5340.27
234_T252_D0.5340.27
102_Q125_V0.5330.27
448_E454_E0.5330.27
215_S248_F0.5330.27
9_D462_S0.5330.27
410_N464_F0.5330.27
65_N107_R0.5330.27
117_T133_V0.5320.27
408_Y445_D0.5320.27
175_Y190_Q0.5320.27
158_I365_C0.5310.27
226_R399_E0.5310.27
210_V418_V0.5300.27
70_L361_A0.5300.27
276_G285_G0.5300.27
91_E94_T0.5290.27
75_E78_T0.5290.27
83_H244_I0.5290.27
414_G418_V0.5290.27
45_L82_G0.5290.27
421_M425_H0.5290.27
24_R27_V0.5280.27
58_I245_A0.5280.27
252_D256_T0.5280.27
143_L146_D0.5270.27
141_Y265_A0.5270.27
51_W327_H0.5270.27
52_R173_L0.5260.27
69_Y384_R0.5250.27
163_H167_R0.5250.27
90_K297_G0.5250.27
437_P440_F0.5250.27
245_A394_I0.5250.27
336_I402_A0.5240.27
20_D457_G0.5240.27
286_P347_P0.5240.27
53_D121_G0.5230.27
140_E153_V0.5230.27
112_S228_C0.5230.27
37_N40_K0.5220.27
92_D99_Q0.5210.26
288_E291_L0.5210.26
27_V158_I0.5190.26
340_P364_L0.5190.26
225_A275_T0.5190.26
27_V51_W0.5180.26
210_V275_T0.5170.26
229_T232_P0.5170.26
25_K107_R0.5170.26
293_I302_L0.5170.26
182_E336_I0.5160.26
239_M311_R0.5160.26
347_P376_I0.5160.26
377_P381_L0.5160.26
51_W219_V0.5160.26
16_Q128_D0.5160.26
162_R328_I0.5150.26
75_E353_K0.5150.26
102_Q249_A0.5150.26
95_R167_R0.5140.26
61_H246_P0.5120.26
199_A232_P0.5120.26
110_V171_E0.5110.26
347_P362_C0.5100.26
98_L101_A0.5100.26
217_C237_A0.5090.26
393_G396_A0.5090.26
112_S221_N0.5080.26
143_L360_Y0.5080.26
123_N331_H0.5080.26
23_M27_V0.5070.26
291_L464_F0.5070.26
151_S290_H0.5070.26
276_G366_T0.5070.26
95_R457_G0.5070.26
304_S308_D0.5060.25
301_V349_L0.5060.25
32_Q273_W0.5060.25
292_V343_A0.5050.25
251_V362_C0.5050.25
115_M118_E0.5050.25
405_M424_A0.5040.25
164_Q228_C0.5040.25
229_T234_T0.5040.25
70_L244_I0.5030.25
238_V316_G0.5030.25
187_F231_L0.5010.25
127_Q429_W0.5000.25
9_D16_Q0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cf4A 2 0.8442 100 0.742 Contact Map
2g40A 2 0.3389 100 0.798 Contact Map
2h88B 1 0.4505 99.7 0.914 Contact Map
1kf6B 1 0.4695 99.5 0.923 Contact Map
4ysxB 1 0.4674 99.5 0.925 Contact Map
2wdqB 1 0.4484 99.4 0.926 Contact Map
2bs2B 1 0.4379 99.3 0.932 Contact Map
4p6vA 1 0.5663 98.8 0.944 Contact Map
3c8yA 1 0.5663 98.5 0.949 Contact Map
1hfeL 2 0.3558 98.3 0.952 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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