GREMLIN Database
STFQ - Side tail fiber protein homolog from lambdoid prophage Qin
UniProt: P77515 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13826
Length: 320 (281)
Sequences: 106 (66)
Seq/√Len: 3.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
192_G196_H5.4150.96
193_A196_H2.7190.52
65_S72_A2.6290.50
17_E23_N2.6270.50
196_H271_A2.6200.49
194_H271_A2.6200.49
191_T194_H2.5990.49
191_T196_H2.5990.49
17_E21_V2.5430.47
189_N196_H2.4330.44
189_N194_H2.4330.44
65_S70_T2.3970.43
189_N192_G2.3150.41
20_E23_N2.2730.40
21_V24_N2.2370.39
20_E24_N2.1880.37
38_G49_I2.1400.36
192_G271_A2.0620.34
89_E123_K2.0250.33
32_N48_L2.0050.32
17_E24_N1.9990.32
26_Y32_N1.9370.31
60_P64_R1.9230.30
258_G262_H1.9150.30
208_H262_H1.9120.30
32_N50_G1.8820.29
66_R72_A1.8230.28
19_Y24_N1.8080.28
36_L48_L1.7990.28
161_S300_A1.7950.27
210_H262_H1.7790.27
191_T271_A1.7550.27
19_Y23_N1.7230.26
170_S286_S1.7210.26
38_G50_G1.7170.26
67_R70_T1.6860.25
34_I44_E1.6850.25
55_S59_A1.6740.25
208_H260_H1.6520.24
48_L55_S1.6500.24
27_P32_N1.6490.24
193_A270_S1.6330.24
19_Y22_Y1.6330.24
32_N36_L1.6190.24
71_D80_L1.6060.23
34_I50_G1.5710.23
261_T291_S1.5400.22
17_E20_E1.5300.22
189_N271_A1.5290.22
193_A271_A1.5270.22
210_H260_H1.5180.22
168_A296_I1.4990.21
25_G50_G1.4920.21
49_I53_G1.4870.21
218_G245_S1.4780.21
69_T80_L1.4720.21
54_T59_A1.4550.20
16_L19_Y1.4430.20
188_T192_G1.4410.20
246_G249_R1.4410.20
50_G55_S1.4180.20
189_N193_A1.4160.20
34_I37_K1.4030.19
284_T291_S1.4020.19
35_H49_I1.3730.19
25_G38_G1.3700.19
219_T246_G1.3680.19
57_A61_A1.3610.19
36_L50_G1.3580.19
271_A275_A1.3500.18
36_L49_I1.3440.18
296_I299_N1.3430.18
65_S69_T1.3430.18
27_P30_Y1.3320.18
72_A76_P1.3280.18
111_M141_I1.3230.18
173_L196_H1.3210.18
173_L194_H1.3210.18
69_T72_A1.3170.18
16_L29_A1.3040.18
256_S277_T1.2970.18
261_T275_A1.2910.17
65_S77_W1.2900.17
34_I48_L1.2860.17
163_T299_N1.2860.17
77_W81_Y1.2840.17
75_S78_A1.2790.17
242_T251_A1.2770.17
25_G32_N1.2750.17
247_Q259_A1.2740.17
67_R71_D1.2670.17
54_T61_A1.2660.17
71_D75_S1.2640.17
187_S194_H1.2430.17
187_S196_H1.2430.17
207_A259_A1.2370.17
32_N38_G1.2350.17
66_R80_L1.2340.17
46_E57_A1.2320.17
139_W154_Q1.2270.16
212_S245_S1.2270.16
91_Y95_A1.2250.16
38_G53_G1.2230.16
204_S259_A1.2120.16
191_T275_A1.2110.16
244_G252_G1.2040.16
65_S80_L1.2010.16
189_N286_S1.2000.16
27_P50_G1.1920.16
16_L21_V1.1870.16
215_A245_S1.1860.16
246_G252_G1.1850.16
194_H202_A1.1830.16
196_H202_A1.1830.16
16_L24_N1.1760.16
60_P69_T1.1720.16
150_A300_A1.1700.16
42_V48_L1.1580.15
36_L40_T1.1580.15
48_L59_A1.1530.15
67_R72_A1.1530.15
32_N55_S1.1450.15
187_S197_S1.1400.15
150_A161_S1.1360.15
45_G53_G1.1050.15
16_L33_I1.1020.15
166_A281_G1.0970.14
49_I55_S1.0970.14
242_T246_G1.0930.14
195_T264_L1.0910.14
187_S192_G1.0910.14
26_Y31_G1.0900.14
37_K53_G1.0870.14
54_T57_A1.0840.14
25_G53_G1.0830.14
70_T73_N1.0820.14
50_G53_G1.0810.14
74_W80_L1.0620.14
32_N35_H1.0570.14
49_I59_A1.0530.14
65_S73_N1.0480.14
49_I54_T1.0470.14
246_G250_N1.0400.14
27_P36_L1.0380.14
28_T34_I1.0350.14
25_G31_G1.0310.14
66_R70_T1.0310.14
72_A77_W1.0290.14
35_H45_G1.0260.13
26_Y48_L1.0170.13
50_G59_A1.0160.13
38_G45_G1.0160.13
69_T74_W1.0120.13
17_E33_I1.0100.13
37_K50_G1.0070.13
42_V45_G1.0020.13
245_S250_N0.9990.13
42_V53_G0.9960.13
26_Y34_I0.9950.13
34_I42_V0.9950.13
165_S293_G0.9930.13
205_A284_T0.9910.13
31_G42_V0.9820.13
26_Y52_S0.9730.13
208_H258_G0.9710.13
63_I66_R0.9690.13
70_T80_L0.9690.13
142_K155_E0.9670.13
38_G55_S0.9650.13
26_Y50_G0.9640.13
66_R69_T0.9610.13
48_L53_G0.9610.13
190_N205_A0.9560.13
24_N29_A0.9530.13
37_K49_I0.9510.13
42_V50_G0.9510.13
21_V33_I0.9460.12
25_G55_S0.9430.12
25_G42_V0.9420.12
36_L55_S0.9330.12
104_V126_V0.9280.12
21_V30_Y0.9250.12
31_G38_G0.9240.12
158_G303_N0.9150.12
16_L27_P0.9080.12
142_K307_T0.9060.12
213_S219_T0.9030.12
31_G55_S0.8990.12
24_N27_P0.8980.12
212_S218_G0.8970.12
80_L84_A0.8920.12
213_S252_G0.8920.12
27_P34_I0.8910.12
197_S263_S0.8900.12
216_F248_T0.8870.12
192_G202_A0.8850.12
28_T32_N0.8780.12
213_S246_G0.8740.12
214_G250_N0.8710.12
66_R71_D0.8710.12
22_Y27_P0.8700.12
20_E31_G0.8650.11
65_S76_P0.8640.11
202_A286_S0.8610.11
34_I46_E0.8590.11
25_G49_I0.8590.11
212_S216_F0.8580.11
36_L53_G0.8560.11
25_G35_H0.8560.11
80_L85_H0.8520.11
16_L22_Y0.8520.11
37_K40_T0.8510.11
214_G248_T0.8510.11
26_Y36_L0.8500.11
71_D78_A0.8500.11
31_G50_G0.8500.11
137_R149_R0.8490.11
44_E47_L0.8450.11
125_A129_P0.8430.11
37_K42_V0.8420.11
210_H258_G0.8420.11
23_N30_Y0.8340.11
32_N37_K0.8340.11
61_A73_N0.8320.11
19_Y30_Y0.8310.11
73_N78_A0.8280.11
155_E307_T0.8270.11
58_H62_F0.8270.11
17_E30_Y0.8240.11
36_L42_V0.8200.11
149_R310_N0.8180.11
38_G48_L0.8150.11
191_T202_A0.8140.11
37_K45_G0.8120.11
16_L23_N0.8120.11
44_E50_G0.8080.11
27_P48_L0.8060.11
19_Y35_H0.8050.11
17_E22_Y0.8040.11
22_Y30_Y0.8020.11
203_N246_G0.7980.11
173_L192_G0.7950.11
16_L20_E0.7950.11
24_N33_I0.7940.11
217_G243_S0.7910.11
38_G42_V0.7880.11
122_P318_R0.7880.11
73_N80_L0.7840.11
131_G318_R0.7810.11
74_W83_S0.7780.10
204_S263_S0.7780.10
35_H38_G0.7780.10
202_A210_H0.7760.10
32_N52_S0.7760.10
65_S71_D0.7680.10
38_G44_E0.7650.10
194_H275_A0.7590.10
196_H275_A0.7590.10
50_G56_G0.7540.10
202_A262_H0.7510.10
31_G48_L0.7500.10
163_T301_A0.7430.10
189_N270_S0.7430.10
215_A243_S0.7420.10
40_T53_G0.7410.10
189_N202_A0.7410.10
72_A83_S0.7380.10
202_A260_H0.7370.10
34_I39_M0.7340.10
246_G255_S0.7320.10
248_T254_T0.7310.10
187_S271_A0.7290.10
204_S284_T0.7280.10
75_S83_S0.7280.10
28_T50_G0.7260.10
254_T258_G0.7250.10
45_G49_I0.7230.10
106_S110_L0.7180.10
243_S247_Q0.7170.10
40_T50_G0.7140.10
27_P38_G0.7140.10
57_A64_R0.7110.10
48_L52_S0.7110.10
207_A256_S0.7100.10
54_T63_I0.7050.10
18_L30_Y0.7020.10
261_T284_T0.7020.10
309_K315_Y0.7020.10
125_A128_Y0.7010.10
277_T284_T0.7000.10
44_E49_I0.6980.10
214_G223_I0.6970.10
215_A246_G0.6930.10
32_N59_A0.6920.10
45_G52_S0.6880.10
171_T319_L0.6880.10
18_L27_P0.6870.10
212_S255_S0.6850.10
43_G50_G0.6820.09
100_P318_R0.6820.09
190_N263_S0.6750.09
71_D76_P0.6730.09
240_S252_G0.6720.09
25_G45_G0.6660.09
81_Y86_P0.6660.09
220_N243_S0.6650.09
215_A221_T0.6650.09
37_K48_L0.6620.09
58_H64_R0.6610.09
24_N30_Y0.6610.09
73_N83_S0.6590.09
272_G281_G0.6560.09
73_N77_W0.6550.09
308_V317_V0.6540.09
33_I36_L0.6490.09
70_T83_S0.6480.09
215_A241_T0.6480.09
272_G276_H0.6420.09
222_S249_R0.6410.09
25_G37_K0.6410.09
97_I104_V0.6410.09
99_W129_P0.6400.09
38_G54_T0.6380.09
74_W79_Q0.6370.09
212_S253_K0.6360.09
31_G34_I0.6340.09
137_R310_N0.6330.09
244_G249_R0.6330.09
151_V183_Y0.6250.09
65_S83_S0.6240.09
290_G294_H0.6230.09
33_I40_T0.6210.09
138_G310_N0.6200.09
188_T270_S0.6180.09
219_T249_R0.6170.09
80_L83_S0.6160.09
254_T257_D0.6130.09
197_S203_N0.6120.09
25_G48_L0.6070.09
219_T248_T0.6050.09
32_N42_V0.6040.09
31_G52_S0.6030.09
70_T77_W0.6030.09
16_L30_Y0.6020.09
27_P37_K0.6010.09
20_E30_Y0.6010.09
32_N49_I0.6000.09
216_F221_T0.5990.09
264_L271_A0.5990.09
34_I56_G0.5990.09
211_K246_G0.5970.09
53_G59_A0.5950.09
190_N204_S0.5950.09
38_G52_S0.5940.09
215_A252_G0.5910.09
190_N193_A0.5910.09
214_G242_T0.5880.09
24_N28_T0.5880.09
33_I49_I0.5860.09
216_F219_T0.5860.09
33_I38_G0.5850.09
23_N33_I0.5830.09
152_L184_G0.5830.09
42_V49_I0.5830.09
70_T75_S0.5830.09
240_S256_S0.5820.09
176_E300_A0.5810.09
20_E27_P0.5780.09
34_I45_G0.5730.08
64_R74_W0.5730.08
37_K43_G0.5720.08
42_V56_G0.5720.08
60_P65_S0.5710.08
166_A272_G0.5680.08
61_A64_R0.5670.08
45_G50_G0.5660.08
219_T247_Q0.5650.08
37_K52_S0.5640.08
81_Y84_A0.5640.08
44_E60_P0.5640.08
40_T49_I0.5630.08
139_W296_I0.5630.08
44_E48_L0.5610.08
214_G245_S0.5600.08
105_P125_A0.5600.08
193_A202_A0.5580.08
35_H50_G0.5550.08
18_L21_V0.5540.08
280_I300_A0.5540.08
43_G53_G0.5500.08
156_Q180_S0.5490.08
64_R72_A0.5490.08
241_T246_G0.5450.08
40_T43_G0.5440.08
77_W80_L0.5420.08
141_I300_A0.5380.08
24_N32_N0.5370.08
190_N270_S0.5370.08
34_I38_G0.5350.08
18_L22_Y0.5350.08
26_Y38_G0.5350.08
305_E310_N0.5330.08
22_Y26_Y0.5330.08
189_N275_A0.5290.08
204_S247_Q0.5260.08
69_T76_P0.5240.08
25_G33_I0.5240.08
97_I106_S0.5240.08
214_G249_R0.5210.08
36_L59_A0.5210.08
45_G55_S0.5200.08
257_D313_F0.5160.08
44_E53_G0.5160.08
50_G54_T0.5150.08
72_A81_Y0.5110.08
100_P129_P0.5100.08
263_S271_A0.5060.08
129_P318_R0.5040.08
99_W128_Y0.5040.08
246_G254_T0.5020.08
206_G258_G0.5010.08
135_D143_G0.5000.08
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2xgfA 3 0.675 100 0.454 Contact Map
1pdiA 3 0.6844 100 0.708 Contact Map
1ocyA 3 0.5062 100 0.773 Contact Map
1h6wA 3 0.3719 99.8 0.836 Contact Map
2fkkA 3 0.4156 71.2 0.966 Contact Map
2fl8A 3 0.4656 2.4 0.984 Contact Map
3qc7A 3 0.2156 2.2 0.984 Contact Map
2gpvG 1 0.0281 2.2 0.985 Contact Map
3e03A 2 0.4 1.7 0.986 Contact Map
1aym4 3 0.0406 1.6 0.986 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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