GREMLIN Database
YAGR - Putative xanthine dehydrogenase YagR molybdenum-binding subunit
UniProt: P77489 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13557
Length: 732 (707)
Sequences: 5620 (3697)
Seq/√Len: 139.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
74_A129_L4.5671.00
177_D290_R4.2591.00
54_V130_V4.2041.00
49_A78_L4.0311.00
119_T122_Q3.8121.00
70_A131_Q3.6441.00
381_I406_R3.6041.00
58_I61_G3.5751.00
179_T288_H3.5391.00
413_G416_Q3.4071.00
294_D298_K3.4031.00
293_A368_L3.3271.00
303_S333_H3.3161.00
480_A519_V3.2391.00
64_T133_H3.1751.00
173_A295_Q3.1361.00
374_I382_L3.1221.00
173_A294_D3.1221.00
74_A122_Q3.1041.00
62_R135_R3.0961.00
299_I365_I3.0271.00
167_G171_S2.9961.00
459_V486_V2.9821.00
164_D167_G2.9251.00
54_V127_A2.9041.00
78_L118_E2.8951.00
177_D288_H2.8851.00
305_E335_G2.8261.00
483_M524_M2.8211.00
58_I136_R2.8111.00
61_G134_Y2.8081.00
378_E382_L2.6211.00
290_R303_S2.6151.00
116_V258_A2.6061.00
65_A133_H2.6031.00
60_K137_N2.5931.00
547_K554_S2.5891.00
206_L220_L2.5721.00
328_A389_P2.5211.00
118_E122_Q2.5111.00
520_Y524_M2.4721.00
205_T234_I2.4441.00
51_G268_V2.4331.00
64_T135_R2.4201.00
298_K382_L2.3921.00
606_R671_E2.3911.00
716_D723_K2.3491.00
118_E264_R2.3131.00
232_R497_D2.2941.00
198_V207_W2.2541.00
203_K499_S2.2421.00
703_A719_I2.2301.00
305_E337_R2.2231.00
68_T72_Q2.2221.00
144_A286_L2.2141.00
412_F590_F2.1971.00
169_F292_G2.1941.00
374_I379_F2.1891.00
309_G343_L2.1751.00
594_G605_R2.1691.00
706_V719_I2.1001.00
51_G114_L2.1001.00
368_L379_F2.0911.00
291_I364_A2.0581.00
407_T410_D2.0501.00
53_I254_L2.0331.00
145_D148_Q2.0301.00
407_T673_I2.0201.00
458_T490_Q2.0101.00
172_A292_G2.0071.00
181_T716_D1.9851.00
408_G590_F1.9651.00
174_V293_A1.9501.00
631_T667_I1.9461.00
378_E381_I1.9381.00
298_K328_A1.9351.00
381_I409_A1.9311.00
458_T492_A1.9131.00
451_V461_V1.9031.00
174_V295_Q1.8991.00
68_T80_V1.8951.00
630_M670_Q1.8901.00
67_D131_Q1.8771.00
71_A130_V1.8761.00
22_H488_L1.8721.00
453_L526_L1.8611.00
406_R410_D1.8581.00
57_A112_I1.8521.00
386_Q402_I1.8511.00
289_L364_A1.8451.00
39_Y267_K1.8391.00
142_S145_D1.8301.00
479_T516_T1.8241.00
62_R103_P1.8171.00
69_D72_Q1.8111.00
161_N333_H1.8091.00
62_R104_T1.7931.00
386_Q389_P1.7871.00
556_T559_E1.7801.00
377_V409_A1.7731.00
116_V262_V1.7561.00
194_A269_M1.7471.00
512_A617_L1.7321.00
454_E460_T1.7261.00
70_A129_L1.7121.00
117_A123_A1.7091.00
203_K230_N1.7041.00
411_K671_E1.6941.00
477_A493_V1.6891.00
294_D300_T1.6861.00
58_I134_Y1.6831.00
78_L264_R1.6751.00
487_P490_Q1.6701.00
645_D648_L1.6681.00
45_A48_A1.6661.00
114_L258_A1.6591.00
438_G587_A1.6571.00
51_G266_V1.6571.00
622_A690_V1.6541.00
454_E458_T1.6481.00
602_V724_L1.6461.00
429_W594_G1.6391.00
400_Q403_E1.6311.00
451_V523_C1.6301.00
79_A261_A1.6251.00
188_M656_M1.6141.00
407_T411_K1.6121.00
23_D620_K1.6071.00
189_A244_G1.6061.00
172_A300_T1.6051.00
179_T286_L1.6011.00
591_V607_M1.5911.00
169_F290_R1.5761.00
77_V117_A1.5691.00
720_T723_K1.5631.00
459_V484_L1.5631.00
607_M630_M1.5541.00
381_I402_I1.5531.00
616_I674_F1.5531.00
174_V371_K1.5471.00
291_I368_L1.5471.00
461_V480_A1.5461.00
370_E707_Y1.5411.00
60_K104_T1.5401.00
589_H607_M1.5361.00
537_D540_Q1.5341.00
74_A126_A1.5331.00
70_A73_K1.5321.00
428_E596_H1.5251.00
291_I299_I1.5241.00
613_A616_I1.5221.00
288_H305_E1.5211.00
483_M685_M1.5151.00
615_R676_D1.5051.00
166_D333_H1.5031.00
127_A130_V1.5031.00
72_Q79_A1.5031.00
114_L254_L1.4961.00
402_I406_R1.4951.00
622_A674_F1.4831.00
449_A519_V1.4571.00
38_A194_A1.4551.00
44_E48_A1.4441.00
151_N154_P1.4441.00
521_A525_K1.4351.00
205_T232_R1.4321.00
411_K673_I1.4241.00
409_A415_K1.4231.00
635_G662_P1.4181.00
227_P230_N1.4171.00
181_T286_L1.4161.00
174_V294_D1.4141.00
221_A231_V1.4121.00
45_A198_V1.4101.00
175_K290_R1.4021.00
604_V634_M1.4011.00
299_I329_G1.3731.00
174_V368_L1.3721.00
226_V231_V1.3711.00
483_M520_Y1.3651.00
430_L597_S1.3651.00
166_D170_T1.3651.00
81_I258_A1.3641.00
481_A491_V1.3631.00
633_G698_V1.3631.00
544_A549_T1.3631.00
408_G588_G1.3631.00
81_I262_V1.3621.00
152_Q155_E1.3621.00
48_A267_K1.3621.00
53_I268_V1.3601.00
431_V594_G1.3571.00
84_S103_P1.3531.00
525_K528_E1.3521.00
39_Y269_M1.3451.00
63_L66_L1.3391.00
169_F301_A1.3341.00
125_A129_L1.3301.00
49_A264_R1.3241.00
174_V372_A1.3231.00
476_L519_V1.3201.00
404_C588_G1.3201.00
224_L256_A1.3151.00
220_L231_V1.3151.00
296_S382_L1.3121.00
541_S548_I1.3121.00
202_N230_N1.3081.00
218_T228_V1.2981.00
168_A301_A1.2941.00
168_A331_N1.2921.00
418_N421_P1.2871.00
178_A367_E1.2871.00
475_I512_A1.2721.00
608_L671_E1.2711.00
165_F168_A1.2671.00
204_L256_A1.2641.00
366_D704_N1.2631.00
35_A237_Y1.2601.00
362_E380_R1.2591.00
122_Q126_A1.2571.00
542_Q549_T1.2541.00
63_L132_A1.2541.00
25_I477_A1.2521.00
349_M632_M1.2501.00
197_A206_L1.2491.00
479_T512_A1.2461.00
165_F169_F1.2431.00
258_A266_V1.2421.00
45_A196_M1.2411.00
52_Y127_A1.2401.00
412_F608_L1.2401.00
411_K610_V1.2391.00
616_I622_A1.2351.00
29_L34_T1.2351.00
287_Q360_A1.2331.00
197_A259_A1.2331.00
197_A255_A1.2311.00
204_L226_V1.2301.00
370_E708_N1.2291.00
293_A372_A1.2291.00
100_L254_L1.2231.00
643_A653_N1.2181.00
280_T347_N1.2161.00
372_A379_F1.2141.00
450_R462_E1.2101.00
593_V706_V1.2091.00
428_E598_A1.2081.00
610_V673_I1.2031.00
408_G610_V1.1981.00
307_W337_R1.1971.00
60_K138_K1.1921.00
166_D303_S1.1911.00
106_E110_Q1.1881.00
366_D376_P1.1881.00
112_I132_A1.1861.00
25_I474_T1.1851.00
55_G274_S1.1801.00
284_A309_G1.1751.00
428_E597_S1.1751.00
207_W234_I1.1730.99
169_F175_K1.1700.99
188_M661_V1.1670.99
178_A371_K1.1660.99
517_S520_Y1.1660.99
626_V630_M1.1660.99
57_A134_Y1.1650.99
525_K529_M1.1630.99
62_R137_N1.1620.99
104_T137_N1.1580.99
77_V126_A1.1570.99
52_Y120_F1.1550.99
82_T100_L1.1540.99
83_A102_G1.1510.99
52_Y124_R1.1490.99
367_E715_R1.1490.99
60_K342_D1.1460.99
600_G724_L1.1460.99
638_L702_I1.1450.99
241_G468_I1.1430.99
602_V638_L1.1400.99
167_G170_T1.1380.99
293_A379_F1.1310.99
28_P32_T1.1260.99
378_E415_K1.1250.99
478_Q618_N1.1210.99
189_A275_I1.1210.99
595_V602_V1.1200.99
359_M703_A1.1190.99
549_T554_S1.1180.99
126_A129_L1.1150.99
151_N155_E1.1110.99
462_E494_H1.1110.99
52_Y123_A1.1090.99
171_S300_T1.1090.99
150_V153_P1.1080.99
477_A488_L1.1070.99
200_D205_T1.1040.99
714_V719_I1.0980.99
104_T156_D1.0960.99
77_V123_A1.0950.99
180_Y364_A1.0950.99
86_A257_L1.0910.99
410_D415_K1.0900.99
570_E573_E1.0890.99
384_D405_L1.0890.99
320_V334_T1.0890.99
407_T610_V1.0860.99
291_I302_I1.0860.99
591_V604_V1.0850.99
66_L132_A1.0760.99
199_W260_R1.0760.99
79_A262_V1.0710.99
535_G540_Q1.0700.99
65_A131_Q1.0690.99
429_W603_R1.0650.99
524_M528_E1.0640.99
48_A196_M1.0640.99
404_C610_V1.0590.99
403_E407_T1.0530.99
112_I134_Y1.0520.99
602_V706_V1.0500.99
460_T494_H1.0430.99
78_L122_Q1.0400.99
480_A523_C1.0360.99
316_P336_L1.0360.99
157_T335_G1.0350.99
120_F124_R1.0350.99
74_A125_A1.0350.99
490_Q546_G1.0340.99
17_V482_E1.0340.99
157_T161_N1.0330.99
644_V651_F1.0290.99
44_E267_K1.0290.99
722_D726_D1.0280.99
293_A299_I1.0270.99
429_W596_H1.0260.99
292_G301_A1.0260.99
176_I371_K1.0250.99
81_I261_A1.0240.99
47_N264_R1.0210.99
168_A292_G1.0210.99
53_I114_L1.0160.99
171_S294_D1.0140.99
612_A677_D1.0110.98
54_V132_A1.0090.98
143_L307_W1.0090.98
365_I379_F1.0090.98
144_A181_T1.0060.98
307_W339_A1.0040.98
49_A262_V1.0030.98
195_S255_A0.9970.98
105_I134_Y0.9970.98
634_M667_I0.9940.98
572_I575_G0.9930.98
198_V205_T0.9920.98
483_M523_C0.9900.98
645_D650_Y0.9880.98
536_F540_Q0.9880.98
176_I293_A0.9870.98
147_K339_A0.9870.98
528_E538_P0.9870.98
292_G300_T0.9850.98
419_A423_Q0.9820.98
60_K139_G0.9820.98
199_W259_A0.9810.98
61_G137_N0.9800.98
165_F303_S0.9800.98
572_I576_T0.9790.98
115_V127_A0.9780.98
530_I560_A0.9760.98
461_V491_V0.9750.98
187_H244_G0.9740.98
417_R592_E0.9740.98
226_V230_N0.9670.98
186_S642_L0.9670.98
719_I723_K0.9670.98
173_A300_T0.9650.98
78_L116_V0.9650.98
209_S245_K0.9650.98
200_D203_K0.9640.98
719_I724_L0.9640.98
169_F303_S0.9630.98
641_E723_K0.9620.98
83_A103_P0.9600.98
543_F548_I0.9600.98
113_A130_V0.9590.98
226_V260_R0.9570.98
63_L112_I0.9570.98
431_V592_E0.9520.98
165_F331_N0.9520.98
51_G258_A0.9490.98
639_M666_D0.9490.98
68_T130_V0.9490.98
283_P356_P0.9460.98
384_D402_I0.9450.98
655_D658_G0.9400.98
217_R228_V0.9400.98
238_I468_I0.9390.98
633_G695_L0.9380.98
421_P425_R0.9370.98
113_A132_A0.9350.97
148_Q151_N0.9350.97
61_G132_A0.9350.97
474_T478_Q0.9340.97
198_V259_A0.9340.97
403_E406_R0.9300.97
21_P623_R0.9270.97
165_F301_A0.9270.97
367_E713_R0.9250.97
176_I291_I0.9250.97
363_I703_A0.9200.97
405_L435_V0.9180.97
285_T319_A0.9170.97
66_L130_V0.9140.97
76_G126_A0.9120.97
88_A92_G0.9090.97
483_M527_R0.9070.97
81_I257_L0.9040.97
530_I557_L0.9020.97
53_I111_A0.9020.97
623_R627_I0.9010.97
211_Q241_G0.9000.97
147_K307_W0.8990.97
366_D380_R0.8980.97
123_A127_A0.8970.97
199_W202_N0.8950.97
667_I670_Q0.8950.97
75_P118_E0.8950.97
80_V113_A0.8950.97
452_H462_E0.8950.97
255_A268_V0.8930.97
29_L473_Y0.8910.97
403_E675_L0.8910.97
377_V405_L0.8860.97
204_L260_R0.8860.97
285_T308_S0.8850.97
609_A630_M0.8830.96
232_R499_S0.8800.96
591_V697_G0.8790.96
377_V435_V0.8780.96
591_V701_A0.8780.96
465_M511_G0.8770.96
140_A146_E0.8760.96
607_M698_V0.8760.96
110_Q313_G0.8760.96
651_F654_H0.8750.96
157_T337_R0.8750.96
521_A524_M0.8750.96
559_E562_A0.8730.96
54_V113_A0.8720.96
273_P654_H0.8710.96
593_V604_V0.8690.96
159_D335_G0.8680.96
231_V256_A0.8670.96
460_T492_A0.8660.96
613_A622_A0.8650.96
50_Y267_K0.8630.96
478_Q619_P0.8630.96
303_S335_G0.8630.96
480_A491_V0.8590.96
592_E606_R0.8570.96
29_L237_Y0.8560.96
327_Y362_E0.8560.96
571_S574_F0.8550.96
246_L507_G0.8520.96
465_M472_S0.8510.96
327_Y380_R0.8490.96
490_Q558_H0.8480.96
144_A179_T0.8480.96
63_L134_Y0.8460.95
81_I116_V0.8450.95
72_Q84_S0.8450.95
168_A300_T0.8440.95
165_F333_H0.8430.95
209_S238_I0.8430.95
623_R674_F0.8420.95
175_K292_G0.8410.95
68_T82_T0.8400.95
290_R333_H0.8390.95
17_V488_L0.8380.95
570_E574_F0.8370.95
76_G118_E0.8350.95
18_V482_E0.8320.95
431_V605_R0.8280.95
180_Y367_E0.8280.95
645_D652_V0.8280.95
164_D331_N0.8270.95
155_E340_T0.8270.95
50_Y120_F0.8270.95
69_D73_K0.8270.95
432_G436_A0.8270.95
193_H275_I0.8240.95
84_S102_G0.8240.95
21_P620_K0.8230.95
470_T506_S0.8200.95
471_G621_T0.8190.95
451_V522_A0.8180.95
172_A301_A0.8160.95
180_Y715_R0.8130.94
30_K37_Y0.8130.94
311_L345_E0.8130.94
543_F557_L0.8130.94
149_A154_P0.8130.94
391_D394_R0.8090.94
453_L557_L0.8090.94
149_A152_Q0.8070.94
547_K556_T0.8070.94
300_T331_N0.8070.94
66_L112_I0.8060.94
707_Y713_R0.8040.94
143_L286_L0.8040.94
141_Y649_G0.8010.94
180_Y363_I0.8010.94
534_V555_A0.8010.94
142_S286_L0.8000.94
606_R669_K0.7990.94
68_T71_A0.7980.94
85_N261_A0.7980.94
168_A172_A0.7980.94
293_A364_A0.7970.94
527_R543_F0.7970.94
533_A563_G0.7970.94
486_V490_Q0.7970.94
258_A262_V0.7970.94
425_R432_G0.7970.94
61_G105_I0.7960.94
634_M702_I0.7960.94
613_A690_V0.7960.94
475_I617_L0.7950.94
475_I621_T0.7950.94
374_I378_E0.7940.94
22_H477_A0.7940.94
177_D303_S0.7930.94
453_L459_V0.7910.94
479_T617_L0.7910.94
202_N260_R0.7900.94
423_Q427_G0.7890.93
150_V155_E0.7870.93
117_A126_A0.7860.93
287_Q304_H0.7860.93
596_H601_E0.7850.93
270_L275_I0.7850.93
224_L257_L0.7830.93
169_F300_T0.7830.93
459_V526_L0.7800.93
232_R498_S0.7800.93
55_G278_N0.7790.93
210_N216_C0.7760.93
451_V526_L0.7750.93
101_G105_I0.7750.93
59_A139_G0.7750.93
192_P269_M0.7750.93
316_P338_L0.7730.93
124_R271_P0.7730.93
324_E332_R0.7730.93
122_Q125_A0.7720.93
120_F271_P0.7700.93
359_M717_Y0.7680.93
163_G168_A0.7670.93
656_M661_V0.7660.92
138_K145_D0.7640.92
297_G374_I0.7640.92
58_I105_I0.7620.92
595_V724_L0.7620.92
642_L651_F0.7610.92
361_L364_A0.7610.92
555_A563_G0.7580.92
196_M267_K0.7580.92
612_A678_T0.7570.92
364_A368_L0.7570.92
426_D594_G0.7560.92
72_Q126_A0.7560.92
141_Y145_D0.7550.92
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101_G110_Q0.7020.89
435_V590_F0.7020.89
178_A715_R0.7020.89
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384_D399_R0.7010.89
71_A77_V0.6990.89
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543_F547_K0.6960.88
41_W207_W0.6950.88
428_E432_G0.6950.88
105_I132_A0.6930.88
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302_I361_L0.6910.88
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571_S575_G0.6840.88
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390_A393_T0.6810.87
533_A555_A0.6810.87
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623_R672_V0.6800.87
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564_G568_A0.6760.87
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530_I548_I0.6580.85
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82_T85_N0.6580.85
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602_V702_I0.6320.83
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555_A558_H0.6310.83
570_E576_T0.6300.83
308_S338_L0.6290.83
511_G515_S0.6280.83
32_T35_A0.6280.83
80_V84_S0.6270.83
613_A674_F0.6250.82
565_R568_A0.6250.82
454_E492_A0.6240.82
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154_P342_D0.6230.82
183_P284_A0.6210.82
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275_I279_T0.6190.82
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358_L700_A0.6170.82
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197_A266_V0.6160.81
343_L644_V0.6160.81
30_K237_Y0.6150.81
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368_L371_K0.6150.81
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519_V523_C0.6090.81
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451_V459_V0.6040.80
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465_M515_S0.6030.80
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98_R102_G0.6010.80
447_S518_G0.6000.80
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165_F173_A0.5830.78
27_G30_K0.5820.78
27_G31_T0.5810.78
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679_D682_S0.5790.77
561_T569_E0.5780.77
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328_A386_Q0.5770.77
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551_G554_S0.5710.76
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207_W236_P0.5660.76
426_D431_V0.5650.76
80_V115_V0.5650.76
184_D642_L0.5650.76
290_R305_E0.5650.76
195_S252_A0.5640.76
50_Y269_M0.5640.76
570_E575_G0.5640.76
159_D333_H0.5640.76
561_T564_G0.5630.75
373_G376_P0.5630.75
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26_D237_Y0.5620.75
100_L111_A0.5620.75
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600_G725_L0.5550.74
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71_A113_A0.5540.74
485_G543_F0.5540.74
602_V721_L0.5520.74
420_T592_E0.5520.74
315_T356_P0.5520.74
410_D413_G0.5510.74
632_M635_G0.5510.74
418_N425_R0.5510.74
553_R559_E0.5510.74
418_N433_H0.5500.74
476_L479_T0.5500.74
631_T634_M0.5500.74
712_I724_L0.5500.74
140_A152_Q0.5490.74
276_P656_M0.5490.74
75_P122_Q0.5480.73
285_T356_P0.5480.73
146_E150_V0.5480.73
432_G438_G0.5480.73
67_D133_H0.5480.73
449_A463_T0.5470.73
310_N346_G0.5470.73
146_E149_A0.5470.73
472_S506_S0.5470.73
114_L268_V0.5460.73
96_T314_G0.5460.73
526_L530_I0.5450.73
206_L256_A0.5450.73
425_R428_E0.5450.73
59_A645_D0.5450.73
447_S514_T0.5440.73
368_L374_I0.5430.73
376_P380_R0.5430.73
433_H708_N0.5430.73
108_Y651_F0.5420.73
563_G567_T0.5420.73
66_L134_Y0.5420.73
634_M639_M0.5420.73
18_V617_L0.5410.72
75_P78_L0.5410.72
633_G637_A0.5410.72
72_Q261_A0.5390.72
297_G379_F0.5390.72
587_A611_C0.5380.72
531_A541_S0.5380.72
41_W45_A0.5380.72
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142_S339_A0.5370.72
606_R670_Q0.5370.72
212_M215_W0.5360.72
420_T423_Q0.5360.72
689_G694_G0.5360.72
387_V400_Q0.5360.72
57_A105_I0.5350.72
284_A343_L0.5350.72
700_A703_A0.5350.72
145_D150_V0.5350.72
436_A701_A0.5340.72
133_H136_R0.5340.72
417_R606_R0.5340.72
79_A258_A0.5330.71
314_G340_T0.5330.71
97_A100_L0.5320.71
479_T685_M0.5320.71
498_S502_V0.5320.71
234_I497_D0.5320.71
527_R548_I0.5320.71
710_T727_K0.5310.71
169_F173_A0.5310.71
473_Y495_L0.5310.71
193_H279_T0.5310.71
293_A371_K0.5310.71
426_D429_W0.5310.71
417_R421_P0.5300.71
379_F383_N0.5300.71
400_Q677_D0.5300.71
412_F588_G0.5300.71
513_N682_S0.5300.71
168_A173_A0.5290.71
167_G331_N0.5290.71
556_T562_A0.5270.71
186_S281_H0.5270.71
371_K713_R0.5260.70
160_K163_G0.5260.70
398_R586_F0.5240.70
220_L253_L0.5240.70
468_I472_S0.5240.70
452_H460_T0.5240.70
451_V491_V0.5230.70
424_V429_W0.5230.70
635_G639_M0.5230.70
418_N435_V0.5230.70
352_P508_G0.5210.70
412_F415_K0.5210.70
209_S241_G0.5210.70
161_N164_D0.5200.70
188_M275_I0.5200.70
589_H609_A0.5190.69
157_T160_K0.5190.69
626_V694_G0.5190.69
428_E434_G0.5180.69
467_D472_S0.5170.69
611_C693_L0.5170.69
463_T476_L0.5160.69
215_W246_L0.5160.69
26_D30_K0.5160.69
450_R575_G0.5160.69
257_L262_V0.5160.69
653_N658_G0.5160.69
589_H697_G0.5140.69
143_L339_A0.5130.69
99_L241_G0.5130.69
528_E531_A0.5130.69
199_W231_V0.5130.69
296_S300_T0.5130.69
161_N166_D0.5130.69
425_R597_S0.5120.68
592_E605_R0.5120.68
639_M661_V0.5110.68
366_D713_R0.5100.68
318_T322_Q0.5100.68
185_Q349_M0.5100.68
300_T330_A0.5090.68
106_E340_T0.5090.68
723_K727_K0.5090.68
397_S679_D0.5090.68
50_Y119_T0.5090.68
89_L225_K0.5090.68
73_K131_Q0.5080.68
127_A131_Q0.5080.68
508_G629_A0.5070.68
139_G342_D0.5070.68
186_S189_A0.5070.68
418_N708_N0.5070.68
369_A379_F0.5060.67
298_K378_E0.5060.67
372_A382_L0.5050.67
710_T714_V0.5050.67
517_S684_P0.5040.67
615_R678_T0.5040.67
63_L71_A0.5040.67
520_Y685_M0.5040.67
536_F541_S0.5030.67
315_T352_P0.5030.67
377_V414_W0.5030.67
22_H474_T0.5030.67
323_S334_T0.5030.67
159_D337_R0.5030.67
49_A266_V0.5030.67
270_L279_T0.5010.67
427_G432_G0.5010.67
398_R688_K0.5010.67
173_A293_A0.5000.67
426_D597_S0.5000.67
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1t3qB 2 0.9863 100 0.12 Contact Map
1rm6A 2 0.9645 100 0.123 Contact Map
1ffvB 2 0.9836 100 0.127 Contact Map
1n62B 2 0.9891 100 0.129 Contact Map
2w3sB 2 0.9727 100 0.141 Contact Map
3uncA 2 0.9863 100 0.148 Contact Map
1dgjA 1 0.9604 100 0.158 Contact Map
3nvzC 2 0.9686 100 0.158 Contact Map
4usaA 2 0.9617 100 0.159 Contact Map
3zyvA 3 0.9795 100 0.16 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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