GREMLIN Database
DXS - 1-deoxy-D-xylulose-5-phosphate synthase
UniProt: P77488 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13612
Length: 620 (579)
Sequences: 12169 (6244)
Seq/√Len: 259.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
506_L615_I4.0451.00
528_T616_K3.7071.00
198_Q201_S3.6231.00
467_Y470_G3.5141.00
377_A389_V3.4701.00
334_A358_K3.3191.00
608_A612_E3.2341.00
449_M460_M3.2041.00
386_K413_P2.9021.00
214_K217_S2.8881.00
607_D610_G2.8421.00
583_L614_K2.7971.00
39_L84_P2.7891.00
208_L236_M2.7821.00
228_R234_K2.5841.00
291_A295_P2.5211.00
228_R233_I2.5101.00
602_A607_D2.4521.00
552_A557_E2.4381.00
277_F281_M2.4301.00
505_K526_N2.3861.00
67_Y219_V2.3741.00
500_K522_A2.3621.00
101_K599_E2.3601.00
195_H198_Q2.3221.00
380_L385_Y2.2831.00
173_D176_V2.2551.00
544_L576_H2.2181.00
599_E602_A2.2131.00
520_K523_E2.1311.00
258_D261_G2.1281.00
407_V416_F2.1221.00
508_I518_A2.1161.00
602_A609_A2.1081.00
446_M473_A2.1071.00
289_E293_K2.1031.00
164_M200_L2.0871.00
206_S236_M2.0741.00
295_P299_H2.0721.00
101_K595_G2.0591.00
544_L577_R2.0581.00
510_N515_M2.0511.00
66_V219_V2.0441.00
596_T599_E2.0351.00
130_G148_C2.0141.00
267_K271_D2.0011.00
319_P327_D1.9801.00
610_G614_K1.9661.00
52_S81_Q1.9601.00
296_I300_A1.9451.00
496_K537_P1.9411.00
161_F203_K1.9371.00
564_G584_N1.9341.00
447_V470_G1.9251.00
540_E544_L1.9221.00
438_S559_N1.8721.00
394_T436_D1.8301.00
520_K608_A1.8231.00
206_S228_R1.8021.00
101_K603_E1.7821.00
59_L177_I1.7781.00
216_F219_V1.7761.00
274_G278_L1.7691.00
519_A529_L1.7551.00
118_L129_A1.7541.00
93_D96_G1.7441.00
548_A552_A1.7131.00
83_Y90_G1.7101.00
151_G154_A1.7071.00
319_P324_I1.7021.00
597_Q601_R1.7021.00
374_V416_F1.6971.00
197_A201_S1.6971.00
243_F252_G1.6921.00
462_Y466_H1.6911.00
140_E385_Y1.6731.00
332_T339_L1.6731.00
266_L269_M1.6541.00
354_E357_R1.6531.00
44_S263_I1.6521.00
443_I446_M1.6431.00
411_K445_E1.6421.00
510_N518_A1.6411.00
191_A194_N1.6291.00
517_E608_A1.6281.00
331_E334_A1.6271.00
85_H90_G1.6261.00
440_L473_A1.6201.00
540_E572_V1.6191.00
516_P520_K1.6171.00
518_A556_V1.6081.00
528_T550_H1.6021.00
216_F220_P1.5931.00
570_N586_G1.5911.00
505_K531_D1.5881.00
69_T115_Y1.5881.00
374_V418_I1.5851.00
94_K97_T1.5771.00
83_Y86_K1.5721.00
436_D475_R1.5711.00
477_P481_A1.5511.00
612_E616_K1.5491.00
505_K551_E1.5491.00
85_H89_T1.5451.00
84_P90_G1.5391.00
447_V539_D1.5371.00
37_R40_L1.5361.00
403_V446_M1.5271.00
354_E358_K1.5241.00
208_L224_E1.5181.00
135_V376_F1.5101.00
524_S527_A1.5091.00
86_K90_G1.5071.00
32_C61_V1.5061.00
570_N574_M1.5051.00
137_A144_R1.5011.00
281_M285_G1.5001.00
587_L590_F1.4981.00
521_V612_E1.4961.00
139_K340_M1.4821.00
524_S612_E1.4811.00
223_K227_K1.4711.00
490_E493_P1.4701.00
283_K286_R1.4661.00
560_A581_P1.4641.00
275_P278_L1.4481.00
415_L464_G1.4411.00
105_H113_S1.4361.00
223_K226_L1.4281.00
497_G542_L1.4271.00
522_A529_L1.4221.00
290_P293_K1.4191.00
40_L266_L1.4141.00
318_L480_N1.4141.00
578_K584_N1.4121.00
579_P582_V1.4061.00
128_S372_H1.4031.00
381_A414_V1.4011.00
67_Y226_L1.3961.00
381_A387_P1.3961.00
145_R173_D1.3931.00
323_K327_D1.3881.00
159_M371_Q1.3851.00
257_H260_L1.3831.00
381_A412_L1.3831.00
83_Y89_T1.3831.00
610_G613_A1.3821.00
411_K469_D1.3801.00
497_G501_R1.3801.00
452_S515_M1.3701.00
378_A407_V1.3661.00
166_H170_I1.3511.00
514_L517_E1.3491.00
595_G600_M1.3481.00
208_L221_P1.3471.00
508_I615_I1.3431.00
86_K89_T1.3381.00
400_Y439_Y1.3371.00
377_A414_V1.3361.00
570_N584_N1.3341.00
52_S56_T1.3341.00
525_L529_L1.3281.00
546_M549_S1.3261.00
106_P109_W1.3231.00
144_R383_G1.3221.00
164_M203_K1.3211.00
329_L388_I1.3191.00
447_V467_Y1.3161.00
517_E520_K1.3121.00
180_D239_P1.3101.00
305_D308_S1.3081.00
501_R523_E1.3051.00
197_A239_P1.3051.00
449_M472_S1.3011.00
263_I267_K1.3001.00
418_I473_A1.2941.00
262_L265_T1.2931.00
494_I497_G1.2881.00
282_T285_G1.2841.00
323_K351_G1.2831.00
299_H303_K1.2801.00
257_H261_G1.2781.00
437_L475_R1.2681.00
507_A550_H1.2681.00
133_I383_G1.2681.00
434_A587_L1.2671.00
493_P496_K1.2581.00
374_V399_A1.2561.00
328_W458_R1.2531.00
113_S116_D1.2471.00
212_G242_L1.2401.00
313_K316_G1.2371.00
334_A359_F1.2371.00
441_R568_G1.2361.00
602_A610_G1.2341.00
137_A146_T1.2261.00
87_I90_G1.2251.00
566_G573_L1.2251.00
75_I133_I1.2211.00
274_G277_F1.2201.00
590_F603_E1.2181.00
176_V248_F1.2141.00
297_T300_A1.2121.00
537_P540_E1.2031.00
276_Q280_I1.2011.00
145_R176_V1.1971.00
126_S150_I1.1971.00
490_E494_I1.1911.00
323_K480_N1.1891.00
341_A388_I1.1861.00
324_I454_E1.1811.00
393_S440_L1.1801.00
567_S571_E1.1791.00
506_L532_M1.1761.00
134_A146_T1.1761.00
319_P323_K1.1731.00
139_K385_Y1.1721.00
396_L418_I1.1711.00
110_R382_I1.1691.00
105_H109_W1.1691.00
477_P513_T1.1661.00
135_V364_F1.1601.00
219_V223_K1.1581.00
177_I222_I1.1541.00
262_L266_L1.1501.00
102_G603_E1.1501.00
609_A613_A1.1501.00
396_L439_Y1.1491.00
377_A390_A1.1491.00
85_H88_L1.1471.00
42_S95_I1.1441.00
470_G545_E1.1431.00
393_S475_R1.1431.00
403_V418_I1.1391.00
600_M604_L1.1321.00
268_N271_D1.1311.00
544_L572_V1.1301.00
530_V546_M1.1281.00
526_N532_M1.1271.00
386_K415_L1.1261.00
501_R533_R1.1221.00
546_M550_H1.1221.00
308_S311_L1.1211.00
265_T268_N1.1211.00
447_V472_S1.1201.00
342_I377_A1.1201.00
332_T465_Y1.1201.00
83_Y91_R1.1171.00
288_Y292_E1.1171.00
75_I130_G1.1141.00
228_R232_H1.1141.00
145_R175_L1.1121.00
500_K523_E1.1111.00
83_Y87_I1.1091.00
83_Y88_L1.1081.00
85_H91_R1.1051.00
138_E173_D1.1031.00
253_P256_G1.1021.00
540_E576_H1.1021.00
166_H376_F1.1021.00
587_L604_L1.1001.00
127_I164_M1.0991.00
467_Y472_S1.0981.00
251_I255_D1.0981.00
336_D386_K1.0951.00
264_T268_N1.0941.00
84_P88_L1.0941.00
197_A207_S1.0921.00
564_G570_N1.0921.00
104_L107_F1.0891.00
509_L537_P1.0891.00
599_E603_E1.0891.00
413_P470_G1.0881.00
258_D262_L1.0831.00
38_Y42_S1.0811.00
590_F604_L1.0811.00
197_A209_R1.0801.00
350_S390_A1.0781.00
263_I266_L1.0781.00
457_C476_Y1.0761.00
135_V170_I1.0731.00
399_A403_V1.0691.00
248_F269_M1.0681.00
277_F280_I1.0671.00
438_S568_G1.0661.00
340_M385_Y1.0641.00
510_N514_L1.0621.00
178_L197_A1.0621.00
374_V407_V1.0601.00
68_N71_F1.0571.00
182_E241_T1.0571.00
292_E296_I1.0551.00
293_K296_I1.0481.00
86_K91_R1.0461.00
498_I501_R1.0461.00
498_I531_D1.0431.00
136_A383_G1.0421.00
169_D193_N1.0421.00
490_E496_K1.0401.00
265_T269_M1.0381.00
584_N587_L1.0371.00
539_D542_L1.0331.00
463_T493_P1.0331.00
570_N589_D1.0321.00
447_V542_L1.0301.00
171_R357_R1.0281.00
118_L382_I1.0271.00
408_A591_F1.0251.00
259_V263_I1.0221.00
330_C358_K1.0211.00
278_L282_T1.0181.00
282_T286_R1.0131.00
482_V516_P1.0101.00
33_D37_R1.0071.00
464_G472_S1.0051.00
108_P120_V1.0031.00
40_L269_M1.0031.00
299_H302_P1.0021.00
145_R226_L1.0021.00
300_A304_F0.9991.00
86_K115_Y0.9991.00
452_S531_D0.9951.00
52_S149_V0.9921.00
437_L559_N0.9901.00
35_L84_P0.9891.00
601_R606_L0.9891.00
606_L610_G0.9891.00
257_H262_L0.9891.00
275_P279_H0.9891.00
42_S96_G0.9871.00
222_I226_L0.9871.00
532_M565_A0.9861.00
201_S209_R0.9861.00
278_L281_M0.9831.00
518_A565_A0.9811.00
220_P224_E0.9811.00
39_L53_G0.9801.00
78_V151_G0.9791.00
128_S375_T0.9791.00
454_E483_G0.9761.00
331_E458_R0.9751.00
449_M534_F0.9731.00
84_P89_T0.9711.00
459_Q492_L0.9681.00
423_I600_M0.9661.00
74_L149_V0.9651.00
87_I277_F0.9641.00
158_G162_E0.9641.00
524_S608_A0.9631.00
403_V416_F0.9601.00
491_K495_G0.9601.00
298_F302_P0.9521.00
107_F110_R0.9501.00
426_A596_T0.9491.00
556_V611_M0.9491.00
538_L543_I0.9481.00
509_L532_M0.9431.00
491_K497_G0.9411.00
177_I266_L0.9411.00
344_P350_S0.9401.00
93_D97_T0.9391.00
441_R571_E0.9371.00
304_F309_G0.9371.00
301_V305_D0.9361.00
177_I240_G0.9351.00
504_E526_N0.9331.00
376_F380_L0.9311.00
341_A363_Y0.9311.00
521_V615_I0.9311.00
497_G500_K0.9261.00
548_A557_E0.9261.00
103_G106_P0.9261.00
88_L91_R0.9221.00
407_V414_V0.9201.00
463_T466_H0.9191.00
56_T59_L0.9191.00
200_L237_V0.9181.00
332_T462_Y0.9171.00
321_Y481_A0.9171.00
275_P280_I0.9151.00
563_G585_I0.9141.00
568_G571_E0.9121.00
340_M380_L0.9091.00
53_G84_P0.9061.00
353_V356_S0.9051.00
186_S347_R0.9031.00
105_H108_P0.9011.00
256_G259_V0.9001.00
110_R119_S0.9001.00
490_E497_G0.8981.00
61_V65_Y0.8971.00
87_I91_R0.8961.00
347_R365_D0.8921.00
106_P110_R0.8921.00
295_P298_F0.8881.00
312_P315_S0.8881.00
585_I614_K0.8851.00
289_E292_E0.8851.00
250_Y268_N0.8821.00
260_L266_L0.8821.00
285_G289_E0.8811.00
312_P316_G0.8791.00
501_R522_A0.8771.00
371_Q402_Q0.8731.00
342_I373_A0.8721.00
70_P91_R0.8721.00
583_L615_I0.8711.00
388_I465_Y0.8711.00
281_M284_K0.8711.00
186_S348_E0.8701.00
84_P91_R0.8701.00
127_I167_A0.8651.00
228_R236_M0.8641.00
492_L497_G0.8631.00
493_P497_G0.8611.00
146_T174_M0.8611.00
127_I148_C0.8601.00
184_S368_I0.8591.00
159_M375_T0.8581.00
518_A529_L0.8581.00
400_Y442_C0.8581.00
217_S220_P0.8571.00
492_L496_K0.8561.00
501_R504_E0.8551.00
517_E601_R0.8530.99
325_F461_L0.8530.99
276_Q279_H0.8520.99
84_P87_I0.8520.99
62_A67_Y0.8520.99
61_V88_L0.8510.99
298_F309_G0.8500.99
64_H85_H0.8490.99
302_P309_G0.8480.99
224_E227_K0.8470.99
356_S359_F0.8440.99
541_A545_E0.8440.99
316_G483_G0.8410.99
462_Y489_L0.8400.99
613_A616_K0.8400.99
259_V262_L0.8400.99
499_V542_L0.8380.99
209_R241_T0.8370.99
338_K385_Y0.8360.99
279_H282_T0.8350.99
103_G107_F0.8340.99
69_T290_P0.8340.99
353_V357_R0.8320.99
150_I155_I0.8320.99
103_G108_P0.8300.99
58_E61_V0.8270.99
127_I160_A0.8260.99
547_A553_L0.8250.99
241_T244_E0.8240.99
38_Y46_S0.8220.99
572_V576_H0.8220.99
330_C359_F0.8210.99
417_A476_Y0.8210.99
507_A546_M0.8190.99
67_Y223_K0.8180.99
492_L498_I0.8170.99
491_K494_I0.8160.99
574_M584_N0.8150.99
545_E549_S0.8140.99
563_G615_I0.8130.99
419_D476_Y0.8110.99
544_L548_A0.8110.99
548_A551_E0.8100.99
521_V585_I0.8080.99
306_P309_G0.8070.99
590_F593_P0.8070.99
121_G124_S0.8050.99
209_R239_P0.8040.99
73_Q144_R0.8020.99
520_K609_A0.8020.99
489_L493_P0.8010.99
506_L552_A0.7990.99
336_D339_L0.7980.99
563_G614_K0.7950.99
153_G184_S0.7950.99
517_E611_M0.7950.99
156_T184_S0.7950.99
397_Q400_Y0.7940.99
511_F537_P0.7930.99
542_L546_M0.7900.99
320_S323_K0.7890.99
165_N192_L0.7890.99
284_K290_P0.7860.99
564_G578_K0.7860.99
125_T375_T0.7860.99
63_L74_L0.7830.99
509_L555_T0.7830.99
489_L492_L0.7810.99
251_I265_T0.7800.99
279_H283_K0.7790.99
173_D233_I0.7770.99
411_K470_G0.7760.99
389_V416_F0.7760.99
304_F308_S0.7760.99
429_Q432_Q0.7750.99
133_I379_G0.7740.99
507_A530_V0.7730.99
495_G499_V0.7720.99
136_A380_L0.7720.99
38_Y87_I0.7720.99
124_S157_A0.7710.99
521_V611_M0.7700.99
496_K500_K0.7700.99
325_F390_A0.7700.99
305_D309_G0.7680.99
439_Y443_I0.7680.99
284_K291_A0.7670.99
508_I554_V0.7670.99
328_W462_Y0.7670.99
37_R41_D0.7660.99
235_G238_V0.7650.99
598_E602_A0.7630.99
62_A215_V0.7630.99
450_T513_T0.7600.99
437_L448_I0.7580.99
586_G589_D0.7580.99
510_N529_L0.7580.99
524_S609_A0.7570.99
377_A380_L0.7570.99
353_V358_K0.7570.99
460_M492_L0.7570.99
500_K519_A0.7550.99
595_G599_E0.7550.99
138_E360_P0.7550.99
514_L556_V0.7550.99
78_V149_V0.7550.99
224_E228_R0.7540.99
561_I586_G0.7520.99
506_L527_A0.7490.99
511_F535_V0.7490.99
72_D77_D0.7490.99
570_N582_V0.7480.99
296_I299_H0.7470.99
104_L109_W0.7470.99
494_I498_I0.7460.99
530_V542_L0.7440.99
355_F360_P0.7440.99
314_S317_G0.7440.99
128_S163_A0.7440.99
54_L269_M0.7440.99
597_Q600_M0.7430.99
452_S498_I0.7420.99
501_R526_N0.7410.99
530_V616_K0.7390.99
539_D543_I0.7390.99
609_A612_E0.7380.99
287_G290_P0.7360.99
578_K581_P0.7350.99
261_G264_T0.7350.99
210_E217_S0.7350.99
403_V440_L0.7310.98
65_Y263_I0.7310.98
267_K270_R0.7300.98
523_E527_A0.7280.98
171_R233_I0.7270.98
447_V541_A0.7270.98
73_Q133_I0.7260.98
257_H270_R0.7250.98
488_P493_P0.7250.98
208_L225_L0.7230.98
488_P491_K0.7230.98
400_Y418_I0.7220.98
380_L387_P0.7220.98
52_S78_V0.7210.98
52_S55_G0.7190.98
199_L203_K0.7190.98
436_D565_A0.7180.98
161_F164_M0.7180.98
327_D354_E0.7170.98
328_W331_E0.7170.98
438_S571_E0.7170.98
297_T301_V0.7140.98
333_A339_L0.7130.98
137_A383_G0.7130.98
287_G291_A0.7120.98
45_R96_G0.7120.98
326_G351_G0.7110.98
582_V587_L0.7100.98
459_Q462_Y0.7080.98
495_G498_I0.7060.98
106_P115_Y0.7060.98
354_E359_F0.7030.98
129_A410_Q0.7020.98
97_T100_Q0.7020.98
571_E574_M0.7020.98
460_M474_V0.7010.98
207_S239_P0.7000.98
44_S266_L0.7000.98
542_L545_E0.6980.98
104_L108_P0.6980.98
413_P468_N0.6960.98
585_I611_M0.6960.98
611_M614_K0.6960.98
56_T81_Q0.6930.98
120_V124_S0.6930.98
408_A443_I0.6900.98
544_L551_E0.6890.98
507_A556_V0.6890.98
307_S311_L0.6890.98
552_A558_E0.6880.98
286_R290_P0.6870.98
484_V519_A0.6860.98
137_A142_K0.6860.98
397_Q436_D0.6860.98
488_P492_L0.6820.98
125_T371_Q0.6820.98
73_Q383_G0.6820.98
355_F359_F0.6810.98
155_I160_A0.6800.98
374_V389_V0.6790.97
326_G330_C0.6780.97
272_L276_Q0.6780.97
439_Y442_C0.6780.97
561_I584_N0.6780.97
524_S528_T0.6780.97
206_S224_E0.6760.97
140_E383_G0.6750.97
62_A219_V0.6740.97
256_G262_L0.6720.97
438_S572_V0.6710.97
509_L543_I0.6710.97
245_E256_G0.6700.97
489_L495_G0.6690.97
266_L270_R0.6690.97
34_E37_R0.6670.97
149_V177_I0.6670.97
497_G530_V0.6660.97
490_E498_I0.6660.97
505_K532_M0.6650.97
87_I92_R0.6650.97
301_V306_P0.6650.97
605_G610_G0.6640.97
79_G108_P0.6620.97
592_I604_L0.6610.97
252_G255_D0.6610.97
463_T467_Y0.6610.97
159_M163_A0.6600.97
560_A580_V0.6590.97
347_R363_Y0.6590.97
440_L443_I0.6580.97
447_V463_T0.6580.97
366_V377_A0.6570.97
79_G179_N0.6550.97
101_K600_M0.6550.97
578_K582_V0.6540.97
459_Q489_L0.6530.97
515_M529_L0.6530.97
503_G526_N0.6520.97
147_V175_L0.6520.97
42_S46_S0.6510.97
256_G260_L0.6510.97
456_E531_D0.6500.97
423_I604_L0.6480.97
415_L472_S0.6480.97
63_L147_V0.6440.97
103_G113_S0.6410.96
248_F268_N0.6390.96
306_P310_C0.6390.96
507_A555_T0.6390.96
284_K288_Y0.6380.96
131_I167_A0.6380.96
536_K539_D0.6370.96
323_K326_G0.6360.96
415_L461_L0.6350.96
62_A66_V0.6350.96
449_M463_T0.6350.96
73_Q137_A0.6340.96
182_E188_N0.6340.96
593_P603_E0.6340.96
39_L43_V0.6330.96
559_N562_M0.6330.96
502_R526_N0.6320.96
552_A555_T0.6320.96
529_L534_F0.6300.96
502_R531_D0.6290.96
612_E615_I0.6270.96
496_K532_M0.6270.96
150_I154_A0.6270.96
419_D474_V0.6250.96
56_T60_T0.6240.96
225_L236_M0.6240.96
491_K498_I0.6230.96
166_H372_H0.6220.96
78_V81_Q0.6210.96
221_P225_L0.6210.96
554_V615_I0.6210.96
446_M471_P0.6200.96
519_A523_E0.6190.96
423_I601_R0.6190.96
448_I475_R0.6180.96
533_R538_L0.6180.96
173_D273_K0.6170.96
348_E365_D0.6170.96
499_V528_T0.6160.96
44_S262_L0.6160.96
423_I587_L0.6150.96
111_G411_K0.6150.96
396_L440_L0.6150.96
303_K307_S0.6130.95
490_E495_G0.6110.95
313_K318_L0.6110.95
508_I556_V0.6090.95
261_G265_T0.6090.95
102_G107_F0.6080.95
70_P89_T0.6080.95
222_I238_V0.6020.95
517_E607_D0.6010.95
507_A559_N0.6010.95
211_G214_K0.6010.95
159_M402_Q0.6000.95
534_F539_D0.6000.95
496_K499_V0.6000.95
524_S529_L0.6000.95
324_I457_C0.5990.95
118_L410_Q0.5990.95
102_G106_P0.5990.95
135_V166_H0.5980.95
567_S573_L0.5980.95
488_P495_G0.5970.95
333_A355_F0.5970.95
555_T566_G0.5970.95
262_L270_R0.5960.95
490_E501_R0.5950.95
462_Y493_P0.5940.95
327_D331_E0.5940.95
328_W332_T0.5930.95
131_I163_A0.5930.95
415_L465_Y0.5930.95
540_E577_R0.5930.95
138_E172_P0.5920.95
121_G126_S0.5910.94
210_E218_G0.5910.94
307_S310_C0.5910.94
243_F247_G0.5900.94
508_I527_A0.5890.94
243_F253_P0.5890.94
272_L275_P0.5880.94
58_E62_A0.5880.94
222_I227_K0.5880.94
505_K530_V0.5860.94
232_H235_G0.5850.94
291_A294_D0.5840.94
497_G503_G0.5840.94
336_D465_Y0.5840.94
447_V545_E0.5820.94
252_G257_H0.5810.94
206_S233_I0.5800.94
382_I412_L0.5790.94
58_E213_K0.5740.94
59_L149_V0.5740.94
355_F358_K0.5740.94
354_E365_D0.5730.94
330_C334_A0.5730.94
245_E248_F0.5730.94
300_A303_K0.5710.93
481_A513_T0.5700.93
585_I606_L0.5700.93
60_T85_H0.5690.93
275_P282_T0.5680.93
102_G105_H0.5670.93
102_G593_P0.5650.93
330_C363_Y0.5620.93
178_L239_P0.5620.93
45_R100_Q0.5610.93
522_A526_N0.5610.93
120_V125_T0.5600.93
377_A387_P0.5590.93
243_F248_F0.5590.93
280_I284_K0.5590.93
298_F301_V0.5580.93
129_A382_I0.5580.93
563_G583_L0.5570.93
235_G239_P0.5560.93
269_M278_L0.5550.92
264_T267_K0.5550.92
319_P454_E0.5540.92
587_L600_M0.5520.92
133_I382_I0.5490.92
366_V372_H0.5470.92
409_I429_Q0.5470.92
401_D407_V0.5470.92
555_T558_E0.5460.92
568_G573_L0.5460.92
147_V226_L0.5440.92
364_F376_F0.5440.92
125_T403_V0.5410.91
145_R174_M0.5400.91
555_T559_N0.5400.91
388_I461_L0.5400.91
163_A372_H0.5400.91
569_V572_V0.5390.91
166_H367_A0.5370.91
593_P596_T0.5370.91
285_G288_Y0.5370.91
379_G382_I0.5360.91
413_P469_D0.5360.91
387_P413_P0.5360.91
247_G250_Y0.5350.91
489_L497_G0.5350.91
491_K501_R0.5340.91
125_T399_A0.5340.91
292_E295_P0.5330.91
374_V403_V0.5330.91
117_V133_I0.5320.91
62_A218_G0.5310.91
324_I328_W0.5310.91
71_F143_N0.5310.91
491_K496_K0.5300.91
332_T336_D0.5290.91
139_K380_L0.5270.90
328_W461_L0.5260.90
564_G574_M0.5250.90
454_E481_A0.5250.90
587_L606_L0.5240.90
583_L587_L0.5230.90
112_E593_P0.5220.90
127_I130_G0.5210.90
205_Y237_V0.5210.90
53_G56_T0.5200.90
341_A355_F0.5200.90
135_V139_K0.5200.90
415_L474_V0.5180.90
493_P501_R0.5170.90
526_N531_D0.5170.90
508_I565_A0.5170.90
492_L500_K0.5170.90
564_G573_L0.5170.90
274_G279_H0.5160.89
437_L511_F0.5150.89
94_K104_L0.5150.89
241_T245_E0.5150.89
552_A556_V0.5140.89
110_R410_Q0.5140.89
459_Q463_T0.5140.89
565_A611_M0.5130.89
150_I160_A0.5130.89
92_R96_G0.5130.89
250_Y254_V0.5120.89
250_Y255_D0.5120.89
100_Q596_T0.5120.89
502_R549_S0.5100.89
434_A560_A0.5090.89
211_G217_S0.5090.89
580_V583_L0.5090.89
102_G112_E0.5090.89
492_L501_R0.5080.89
496_K540_E0.5080.89
133_I146_T0.5070.89
507_A528_T0.5070.89
406_D409_I0.5060.89
399_A402_Q0.5060.89
46_S98_I0.5050.88
104_L110_R0.5040.88
371_Q401_D0.5040.88
492_L495_G0.5030.88
56_T78_V0.5030.88
109_W112_E0.5030.88
329_L333_A0.5030.88
375_T402_Q0.5020.88
489_L496_K0.5010.88
215_V218_G0.5000.88
173_D206_S0.5000.88
500_K526_N0.5000.88
107_F113_S0.5000.88
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2o1sA 2 0.8645 100 0.241 Contact Map
2o1xA 2 0.9226 100 0.244 Contact Map
1r9jA 2 0.9355 100 0.268 Contact Map
1itzA 2 0.9387 100 0.279 Contact Map
3rimA 2 0.9548 100 0.281 Contact Map
4kxvA 2 0.9435 100 0.289 Contact Map
1gpuA 2 0.9306 100 0.29 Contact Map
3uk1A 2 0.9339 100 0.29 Contact Map
2r8oA 2 0.9339 100 0.298 Contact Map
2qtcA 2 0.9548 100 0.3 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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