GREMLIN Database
YCJV - Putative uncharacterized ABC transporter ATP-binding protein YcjV
UniProt: P77481 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13919
Length: 360 (311)
Sequences: 21384 (15337)
Seq/√Len: 869.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
217_G221_T4.3171.00
34_V202_A4.0181.00
60_D67_R4.0161.00
8_H22_D3.8501.00
31_E204_R3.6681.00
5_S26_E3.5931.00
300_A316_T3.5281.00
7_Q60_D3.5121.00
120_Q125_R3.3921.00
18_H21_K3.2081.00
112_D116_N2.9211.00
21_K212_I2.8061.00
214_Q228_N2.8031.00
303_S317_T2.7681.00
107_A110_V2.6351.00
127_Y130_R2.6061.00
33_I206_V2.5931.00
28_A31_E2.5201.00
218_A221_T2.5041.00
94_Y98_A2.4591.00
6_L9_I2.4551.00
94_Y129_K2.3811.00
11_K49_M2.3671.00
10_Q58_G2.3631.00
10_Q18_H2.3621.00
5_S62_L2.3521.00
7_Q62_L2.3471.00
114_R152_E2.3311.00
8_H24_N2.2911.00
10_Q22_D2.2701.00
12_I18_H2.2551.00
77_N154_G2.1971.00
94_Y112_D2.0901.00
94_Y116_N2.0861.00
20_V49_M2.0241.00
4_L155_V2.0121.00
123_G172_Q1.9881.00
9_I56_I1.9771.00
199_M220_K1.9521.00
47_L191_V1.9471.00
64_D154_G1.9241.00
49_M56_I1.8891.00
119_A128_L1.8831.00
209_K214_Q1.8751.00
206_V216_V1.8651.00
11_K57_S1.8491.00
62_L67_R1.8411.00
206_V213_V1.8131.00
113_E117_W1.7501.00
110_V113_E1.7221.00
229_M280_V1.7161.00
11_K54_E1.7091.00
50_I189_I1.7051.00
109_E113_E1.6831.00
114_R117_W1.6721.00
94_Y115_V1.6701.00
49_M61_L1.6281.00
118_A150_V1.6191.00
229_M242_F1.5831.00
48_R54_E1.5391.00
63_I68_M1.5381.00
68_M71_V1.5251.00
301_K317_T1.4931.00
67_R70_D1.4911.00
6_L25_L1.4681.00
66_K154_G1.4651.00
98_A115_V1.4621.00
12_I57_S1.4541.00
158_M188_M1.4521.00
23_F46_T1.4391.00
6_L50_I1.4201.00
259_L262_P1.4161.00
117_W120_Q1.4021.00
233_G242_F1.4021.00
229_M233_G1.3861.00
47_L157_L1.3811.00
56_I61_L1.3791.00
106_I110_V1.3681.00
110_V114_R1.3601.00
122_L146_G1.3581.00
274_S277_K1.3521.00
33_I216_V1.3501.00
27_I33_I1.3491.00
106_I111_I1.3471.00
246_T278_P1.3281.00
116_N120_Q1.3221.00
242_F280_V1.3191.00
92_T131_K1.3191.00
220_K224_N1.3111.00
91_M99_F1.2991.00
66_K71_V1.2971.00
305_A314_L1.2921.00
25_L206_V1.2671.00
7_Q24_N1.2611.00
60_D69_N1.2521.00
10_Q21_K1.2481.00
6_L46_T1.2341.00
33_I204_R1.2211.00
92_T95_D1.2211.00
256_T259_L1.2111.00
181_H186_T1.1851.00
20_V46_T1.1661.00
116_N128_L1.1621.00
252_F255_E1.1501.00
79_A148_A1.1461.00
108_K112_D1.1361.00
28_A204_R1.1331.00
257_L261_I1.1321.00
95_D102_K1.1291.00
90_H133_G1.1281.00
181_H188_M1.1271.00
273_E277_K1.1261.00
98_A111_I1.1241.00
93_V135_L1.1221.00
254_T257_L1.1151.00
221_T225_Q1.1141.00
244_R278_P1.1111.00
12_I19_V1.1101.00
95_D98_A1.1021.00
100_G151_R1.1011.00
257_L260_T1.1001.00
48_R53_L1.0961.00
111_I115_V1.0951.00
259_L264_E1.0951.00
12_I58_G1.0931.00
20_V23_F1.0921.00
56_I69_N1.0921.00
9_I49_M1.0921.00
117_W152_E1.0821.00
204_R216_V1.0721.00
102_K108_K1.0711.00
41_C208_M1.0701.00
61_L68_M1.0501.00
244_R280_V1.0431.00
178_S201_M1.0361.00
249_G252_F1.0341.00
259_L263_E1.0311.00
46_T208_M1.0281.00
258_K261_I1.0211.00
240_M282_G1.0141.00
62_L65_G1.0081.00
88_Y100_G1.0071.00
213_V216_V1.0001.00
96_N147_R0.9991.00
12_I15_N0.9931.00
25_L216_V0.9921.00
8_H58_G0.9831.00
29_D64_D0.9831.00
269_L273_E0.9811.00
71_V75_A0.9791.00
192_T198_A0.9791.00
31_E203_T0.9751.00
245_G279_I0.9751.00
79_A153_A0.9711.00
207_I222_V0.9641.00
263_E266_L0.9621.00
117_W121_I0.9621.00
104_Q151_R0.9621.00
5_S65_G0.9601.00
283_I288_I0.9601.00
256_T260_T0.9461.00
13_Y19_V0.9461.00
99_F103_M0.9451.00
178_S182_Q0.9441.00
224_N307_L0.9401.00
294_E297_N0.9401.00
241_N245_G0.9391.00
87_L132_P0.9351.00
261_I264_E0.9321.00
32_F201_M0.9301.00
273_E276_H0.9291.00
252_F256_T0.9291.00
27_I187_T0.9271.00
34_V198_A0.9261.00
51_A157_L0.9261.00
250_D253_V0.9251.00
116_N125_R0.9201.00
97_M150_V0.9191.00
94_Y128_L0.9171.00
258_K263_E0.9171.00
152_E186_T0.9161.00
258_K262_P0.9121.00
190_Y202_A0.9121.00
32_F181_H0.9111.00
118_A149_I0.9101.00
9_I61_L0.9101.00
108_K111_I0.9071.00
131_K134_A0.9061.00
29_D154_G0.9061.00
88_Y91_M0.9051.00
36_V207_I0.9041.00
97_M146_G0.9021.00
207_I231_V0.9021.00
260_T263_E0.9021.00
272_Q276_H0.9001.00
72_P75_A0.8991.00
91_M95_D0.8861.00
118_A121_I0.8861.00
170_R194_D0.8851.00
253_V257_L0.8801.00
274_S278_P0.8781.00
162_L177_I0.8761.00
307_L312_F0.8761.00
262_P265_K0.8731.00
178_S200_T0.8711.00
171_V175_A0.8661.00
32_F188_M0.8661.00
98_A102_K0.8651.00
220_K307_L0.8591.00
30_K187_T0.8561.00
79_A151_R0.8561.00
162_L190_Y0.8521.00
112_D115_V0.8511.00
276_H279_I0.8481.00
209_K230_F0.8431.00
6_L61_L0.8431.00
180_L186_T0.8391.00
97_M119_A0.8391.00
156_F186_T0.8311.00
267_A271_T0.8271.00
130_R134_A0.8241.00
118_A122_L0.8201.00
223_Y286_E0.8121.00
283_I286_E0.8101.00
281_M284_R0.7991.00
291_D294_E0.7931.00
49_M57_S0.7921.00
262_P266_L0.7921.00
223_Y226_P0.7901.00
119_A124_L0.7891.00
271_T274_S0.7871.00
154_G186_T0.7831.00
15_N18_H0.7781.00
302_I314_L0.7761.00
260_T264_E0.7751.00
258_K264_E0.7711.00
257_L262_P0.7681.00
256_T262_P0.7671.00
91_M96_N0.7661.00
107_A111_I0.7661.00
145_L158_M0.7651.00
35_F208_M0.7631.00
284_R288_I0.7621.00
219_P223_Y0.7611.00
153_A156_F0.7551.00
7_Q26_E0.7541.00
35_F206_V0.7501.00
30_K185_N0.7481.00
106_I114_R0.7451.00
255_E258_K0.7431.00
14_D18_H0.7381.00
257_L264_E0.7361.00
278_P282_G0.7361.00
160_E193_H0.7351.00
240_M243_I0.7321.00
35_F46_T0.7301.00
83_Q164_N0.7271.00
308_T313_M0.7251.00
132_P143_V0.7251.00
78_I155_V0.7241.00
256_T261_I0.7201.00
167_A171_V0.7171.00
96_N132_P0.7151.00
274_S279_I0.7101.00
196_T308_T0.7081.00
115_V118_A0.7021.00
198_A202_A0.6991.00
63_I78_I0.6981.00
209_K212_I0.6981.00
270_K274_S0.6961.00
269_L272_Q0.6951.00
191_V195_Q0.6881.00
290_P293_Q0.6861.00
44_S48_R0.6861.00
261_I266_L0.6861.00
41_C46_T0.6851.00
308_T311_E0.6851.00
257_L263_E0.6831.00
168_K233_G0.6831.00
79_A188_M0.6831.00
173_M176_E0.6791.00
38_P41_C0.6771.00
22_D58_G0.6761.00
158_M190_Y0.6761.00
33_I189_I0.6751.00
251_K255_E0.6731.00
276_H283_I0.6721.00
261_I265_K0.6691.00
271_T275_L0.6681.00
102_K111_I0.6661.00
97_M100_G0.6651.00
125_R128_L0.6631.00
269_L276_H0.6601.00
304_V307_L0.6591.00
167_A174_R0.6581.00
248_D253_V0.6581.00
243_I247_I0.6561.00
204_R215_Q0.6561.00
302_I316_T0.6541.00
300_A303_S0.6541.00
13_Y54_E0.6511.00
251_K254_T0.6511.00
85_Y164_N0.6501.00
286_E290_P0.6481.00
119_A122_L0.6481.00
260_T265_K0.6461.00
276_H281_M0.6381.00
298_I301_K0.6361.00
255_E259_L0.6361.00
267_A270_K0.6361.00
21_K210_D0.6351.00
49_M54_E0.6331.00
179_K304_V0.6331.00
124_L127_Y0.6321.00
87_L96_N0.6311.00
196_T200_T0.6311.00
51_A80_M0.6311.00
291_D295_E0.6241.00
11_K45_T0.6231.00
94_Y97_M0.6191.00
93_V143_V0.6161.00
114_R118_A0.6151.00
92_T129_K0.6151.00
126_E139_Q0.6131.00
268_V271_T0.6131.00
100_G147_R0.6131.00
83_Q137_G0.6121.00
250_D255_E0.6111.00
259_L265_K0.6101.00
176_E179_K0.6081.00
32_F190_Y0.6081.00
171_V196_T0.6021.00
94_Y111_I0.6011.00
109_E112_D0.6011.00
208_M213_V0.6001.00
281_M285_P0.5991.00
142_R165_L0.5971.00
295_E301_K0.5971.00
171_V237_S0.5951.00
118_A146_G0.5951.00
285_P289_H0.5941.00
220_K312_F0.5931.00
253_V256_T0.5911.00
297_N300_A0.5891.00
301_K305_A0.5891.00
175_A304_V0.5871.00
282_G285_P0.5871.00
178_S307_L0.5871.00
252_F257_L0.5861.00
12_I21_K0.5851.00
269_L274_S0.5841.00
256_T264_E0.5841.00
242_F245_G0.5831.00
304_V315_Y0.5821.00
285_P288_I0.5821.00
256_T263_E0.5811.00
257_L265_K0.5801.00
231_V235_I0.5801.00
23_F213_V0.5801.00
164_N174_R0.5801.00
157_L189_I0.5801.00
25_L213_V0.5771.00
175_A315_Y0.5771.00
238_P242_F0.5761.00
305_A308_T0.5761.00
207_I226_P0.5751.00
31_E216_V0.5731.00
222_V226_P0.5711.00
278_P284_R0.5701.00
239_A243_I0.5701.00
177_I188_M0.5691.00
253_V258_K0.5691.00
277_K284_R0.5691.00
295_E299_S0.5681.00
305_A312_F0.5671.00
251_K258_K0.5661.00
217_G222_V0.5651.00
239_A242_F0.5651.00
18_H22_D0.5651.00
156_F188_M0.5651.00
259_L266_L0.5651.00
276_H284_R0.5641.00
302_I309_G0.5631.00
294_E299_S0.5631.00
219_P222_V0.5621.00
113_E116_N0.5621.00
294_E298_I0.5611.00
291_D296_N0.5601.00
270_K273_E0.5591.00
272_Q284_R0.5591.00
272_Q275_L0.5581.00
279_I283_I0.5551.00
163_S167_A0.5551.00
248_D251_K0.5551.00
230_F233_G0.5541.00
127_Y139_Q0.5531.00
205_I219_P0.5521.00
248_D258_K0.5511.00
275_L279_I0.5511.00
68_M78_I0.5491.00
99_F102_K0.5481.00
270_K275_L0.5481.00
312_F315_Y0.5471.00
230_F234_F0.5461.00
170_R197_E0.5461.00
226_P231_V0.5441.00
155_V187_T0.5441.00
88_Y96_N0.5431.00
60_D70_D0.5431.00
276_H280_V0.5421.00
269_L275_L0.5421.00
237_S313_M0.5411.00
172_Q176_E0.5401.00
281_M288_I0.5401.00
267_A274_S0.5391.00
77_N104_Q0.5381.00
241_N244_R0.5341.00
283_I290_P0.5331.00
250_D254_T0.5331.00
55_E70_D0.5321.00
269_L283_I0.5321.00
253_V260_T0.5321.00
303_S315_Y0.5301.00
249_G256_T0.5291.00
272_Q278_P0.5291.00
10_Q20_V0.5281.00
111_I114_R0.5261.00
123_G176_E0.5251.00
241_N247_I0.5241.00
89_P133_G0.5241.00
270_K277_K0.5241.00
254_T259_L0.5241.00
274_S283_I0.5231.00
249_G254_T0.5231.00
191_V194_D0.5231.00
71_V74_K0.5221.00
81_V141_Q0.5221.00
39_S160_E0.5221.00
35_F189_I0.5221.00
195_Q234_F0.5181.00
124_L128_L0.5171.00
245_G252_F0.5171.00
292_A295_E0.5161.00
13_Y45_T0.5151.00
232_S236_G0.5151.00
268_V275_L0.5131.00
288_I291_D0.5131.00
278_P292_A0.5131.00
113_E120_Q0.5121.00
81_V148_A0.5121.00
32_F177_I0.5111.00
81_V145_L0.5101.00
11_K20_V0.5101.00
84_N140_R0.5101.00
250_D257_L0.5091.00
181_H203_T0.5091.00
179_K303_S0.5091.00
39_S193_H0.5071.00
284_R287_D0.5071.00
305_A309_G0.5061.00
254_T258_K0.5051.00
29_D185_N0.5041.00
123_G126_E0.5041.00
69_N73_A0.5011.00
22_D212_I0.5001.00
4_L63_I0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1v43A 2 0.9639 100 0.163 Contact Map
2it1A 1 0.9944 100 0.164 Contact Map
1g291 4 0.9972 100 0.174 Contact Map
2yyzA 1 0.9806 100 0.174 Contact Map
3rlfA 2 0.9889 100 0.178 Contact Map
1oxxK 1 0.9444 100 0.188 Contact Map
3fvqA 2 0.95 100 0.21 Contact Map
4tquS 2 0.9917 100 0.212 Contact Map
1z47A 2 0.9472 100 0.214 Contact Map
3d31A 2 0.9417 100 0.223 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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