GREMLIN Database
PAAZ - Bifunctional protein PaaZ
UniProt: P77455 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13735
Length: 681 (662)
Sequences: 416 (206)
Seq/√Len: 8.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
429_T435_A6.5741.00
269_V273_Q5.8961.00
8_L45_R5.3441.00
312_S403_L4.8380.99
80_E93_R4.8050.99
587_V655_V4.4680.99
305_Q407_Q4.4410.99
191_Q195_K4.1920.98
82_F196_S4.0170.97
114_G173_L3.8380.97
484_L489_A3.7700.96
264_V416_A3.7120.96
578_G619_K3.6560.95
189_L194_V3.6260.95
237_G255_M3.6180.95
504_T518_K3.5520.95
74_H78_E3.5420.94
190_T194_V3.4760.94
198_V201_G3.4710.94
78_E196_S3.3900.93
45_R179_I3.3580.93
10_G205_E3.3180.92
98_V289_T3.1670.90
307_L310_A3.1030.89
189_L192_A3.0770.89
72_A108_F3.0740.89
82_F193_M3.0560.89
194_V208_I2.8710.85
24_H88_Q2.8700.85
283_V301_I2.8540.85
135_E459_E2.8380.84
262_C425_G2.8380.84
574_E600_V2.8180.84
47_F51_K2.7950.83
323_V333_K2.7400.82
46_Q49_I2.7310.82
34_V184_T2.7160.82
567_M580_R2.6970.81
586_F590_A2.6600.80
147_K252_P2.6140.79
553_V567_M2.5420.77
124_W491_K2.5290.76
579_E620_P2.5000.76
379_L401_A2.4610.74
554_N558_L2.4510.74
189_L201_G2.4440.74
622_D657_N2.4330.74
168_L172_W2.4200.73
428_V452_L2.4080.73
308_V403_L2.4010.72
413_L441_D2.3940.72
196_S201_G2.3920.72
190_T201_G2.3900.72
430_A455_E2.3830.72
194_V201_G2.3210.70
153_H178_A2.3200.70
86_S96_S2.3180.70
164_M193_M2.3090.69
280_I315_L2.2910.69
126_E144_L2.2840.68
171_T178_A2.2710.68
76_L79_K2.2410.67
49_I54_P2.2390.67
451_I509_I2.2350.67
279_F301_I2.2000.65
268_D434_I2.1650.64
375_F378_T2.1650.64
625_Q660_Q2.1570.64
80_E84_A2.1480.63
430_A454_E2.1080.62
347_Q378_T2.0950.61
8_L179_I2.0690.60
340_A343_R2.0520.60
84_A87_A2.0180.58
559_S586_F2.0170.58
364_G378_T1.9950.57
427_L438_F1.9550.56
549_E553_V1.9320.55
164_M180_I1.9170.54
97_W101_E1.9100.54
189_L196_S1.9040.54
191_Q194_V1.8890.53
194_V199_D1.8880.53
161_C193_M1.8800.53
263_C450_Q1.8590.52
122_T146_S1.8550.52
308_V405_P1.8440.51
192_A196_S1.8400.51
359_E383_P1.8370.51
35_T38_G1.8230.50
633_K653_V1.8170.50
10_G48_A1.7820.49
409_Q434_I1.7820.49
653_V668_I1.7670.48
153_H493_Y1.7620.48
192_A201_G1.7610.48
26_I326_D1.7440.47
531_F633_K1.7420.47
322_V333_K1.7370.47
569_K580_R1.7340.47
588_L609_L1.7090.46
196_S200_S1.7050.46
221_H243_Q1.6850.45
190_T196_S1.6790.45
111_A627_R1.6790.45
347_Q375_F1.6530.44
302_I412_A1.6470.43
453_N502_S1.6460.43
529_K538_D1.6250.42
588_L668_I1.6140.42
196_S199_D1.6100.42
96_S189_L1.6000.41
622_D658_Q1.5990.41
8_L36_S1.5950.41
199_D202_L1.5850.41
46_Q179_I1.5850.41
575_S646_T1.5850.41
193_M255_M1.5640.40
153_H229_T1.5570.40
168_L208_I1.5560.40
65_A114_G1.5540.40
575_S648_V1.5520.40
82_F255_M1.5510.39
310_A313_D1.5470.39
60_T121_D1.5390.39
57_R146_S1.5380.39
125_P505_M1.5370.39
309_N323_V1.5370.39
189_L199_D1.5290.39
410_R437_Q1.5160.38
531_F616_E1.5000.37
74_H196_S1.4910.37
408_N411_H1.4890.37
189_L200_S1.4870.37
194_V198_V1.4810.37
74_H77_S1.4790.37
579_E619_K1.4710.36
616_E668_I1.4690.36
190_T200_S1.4680.36
190_T210_L1.4540.36
263_C426_T1.4450.35
21_L30_A1.4430.35
454_E457_A1.4420.35
82_F237_G1.4420.35
569_K620_P1.4360.35
393_A420_G1.4360.35
301_I426_T1.4290.35
192_A199_D1.4250.35
78_E82_F1.4230.35
180_I193_M1.4200.34
141_R512_Q1.4120.34
93_R97_W1.4050.34
430_A456_S1.4010.34
430_A453_N1.3900.33
558_L650_E1.3890.33
216_G221_H1.3840.33
143_L264_V1.3810.33
301_I401_A1.3760.33
312_S361_R1.3760.33
338_V490_V1.3750.33
531_F635_L1.3710.33
633_K668_I1.3700.33
553_V580_R1.3700.33
45_R49_I1.3650.32
361_R403_L1.3540.32
283_V315_L1.3470.32
554_N590_A1.3440.32
549_E620_P1.3430.32
109_T469_Q1.3430.32
565_A581_V1.3410.32
217_D221_H1.3390.32
556_A567_M1.3380.31
61_F173_L1.3340.31
152_V219_L1.3340.31
287_M298_I1.3300.31
636_K648_V1.3270.31
89_T100_I1.3260.31
8_L39_L1.3220.31
588_L616_E1.3200.31
519_V539_S1.3150.31
572_A657_N1.3080.30
531_F668_I1.3070.30
502_S505_M1.3070.30
578_G587_V1.3040.30
161_C180_I1.3040.30
215_A219_L1.3000.30
127_D130_I1.2940.30
121_D511_K1.2930.30
96_S100_I1.2900.30
636_K674_R1.2890.30
133_S137_G1.2810.29
553_V558_L1.2670.29
632_R650_E1.2640.29
345_D348_E1.2630.29
223_D484_L1.2600.29
442_A449_I1.2580.29
590_A668_I1.2530.29
636_K646_T1.2470.28
270_T273_Q1.2470.28
111_A671_L1.2430.28
189_L198_V1.2410.28
282_E285_R1.2390.28
8_L49_I1.2380.28
269_V272_D1.2250.28
612_L666_Y1.2180.27
191_Q201_G1.2140.27
284_V315_L1.2140.27
274_P454_E1.2130.27
46_Q405_P1.2130.27
308_V381_Y1.2090.27
172_W178_A1.2040.27
425_G446_H1.2020.27
558_L562_H1.1940.27
118_L124_W1.1940.27
558_L586_F1.1910.27
237_G456_S1.1900.26
96_S332_V1.1870.26
193_M196_S1.1860.26
192_A200_S1.1850.26
284_V318_R1.1830.26
558_L590_A1.1820.26
586_F623_T1.1780.26
272_D277_A1.1690.26
531_F674_R1.1650.26
532_E633_K1.1640.26
194_V200_S1.1630.26
616_E661_T1.1610.26
313_D509_I1.1570.25
161_C237_G1.1570.25
192_A195_K1.1530.25
557_C562_H1.1430.25
81_R84_A1.1420.25
349_K352_I1.1330.25
572_A666_Y1.1260.24
133_S302_I1.1250.24
648_V671_L1.1250.24
407_Q411_H1.1250.24
549_E554_N1.1250.24
269_V434_I1.1250.24
610_E613_R1.1230.24
224_S420_G1.1220.24
545_R590_A1.1220.24
22_I34_V1.1220.24
110_Y264_V1.1200.24
65_A113_L1.1160.24
260_L416_A1.1160.24
616_E667_S1.1130.24
108_F620_P1.1130.24
386_D418_A1.1120.24
378_T615_I1.1100.24
338_V345_D1.1090.24
451_I505_M1.1000.24
135_E371_A1.0980.24
281_R333_K1.0930.24
570_I586_F1.0930.24
7_F469_Q1.0910.23
227_V493_Y1.0890.23
643_E646_T1.0860.23
211_I315_L1.0850.23
59_M67_M1.0820.23
267_E434_I1.0810.23
554_N557_C1.0810.23
519_V627_R1.0810.23
216_G220_D1.0800.23
526_P651_W1.0710.23
121_D146_S1.0690.23
73_K108_F1.0670.23
66_A652_A1.0630.23
552_I620_P1.0630.23
648_V668_I1.0620.23
554_N586_F1.0560.22
229_T255_M1.0550.22
559_S576_I1.0550.22
546_T623_T1.0540.22
66_A120_D1.0520.22
195_K199_D1.0470.22
111_A336_A1.0460.22
5_A610_E1.0450.22
84_A328_A1.0430.22
590_A648_V1.0400.22
111_A610_E1.0380.22
113_L130_I1.0370.22
184_T187_A1.0300.22
58_A535_Q1.0270.22
567_M620_P1.0260.22
94_A442_A1.0260.22
355_A360_I1.0220.21
364_G615_I1.0170.21
559_S648_V1.0110.21
49_I247_V1.0040.21
121_D336_A1.0040.21
630_C652_A1.0020.21
35_T60_T1.0020.21
264_V536_P1.0010.21
559_S590_A1.0000.21
543_P550_A1.0000.21
16_R19_S0.9980.21
616_E674_R0.9980.21
569_K579_E0.9960.21
172_W671_L0.9940.21
294_K492_H0.9910.21
427_L451_I0.9860.20
218_L222_L0.9850.20
493_Y580_R0.9820.20
197_I202_L0.9810.20
46_Q223_D0.9780.20
131_P134_K0.9740.20
425_G449_I0.9730.20
386_D411_H0.9720.20
111_A173_L0.9670.20
198_V208_I0.9650.20
120_D588_L0.9620.20
587_V619_K0.9600.20
70_A216_G0.9570.20
384_Q387_E0.9570.20
197_I487_L0.9550.20
26_I633_K0.9540.20
171_T285_R0.9510.20
108_F468_P0.9450.19
416_A446_H0.9420.19
113_L487_L0.9390.19
195_K201_G0.9390.19
520_E538_D0.9380.19
627_R630_C0.9370.19
19_S184_T0.9340.19
178_A653_V0.9320.19
202_L550_A0.9320.19
262_C428_V0.9310.19
73_K93_R0.9300.19
654_E662_P0.9300.19
75_L104_I0.9280.19
588_L671_L0.9280.19
195_K409_Q0.9270.19
193_M237_G0.9240.19
26_I250_S0.9240.19
147_K176_M0.9230.19
70_A202_L0.9220.19
501_G509_I0.9180.19
588_L633_K0.9170.19
45_R176_M0.9170.19
270_T307_L0.9170.19
106_T315_L0.9150.19
600_V666_Y0.9090.19
572_A600_V0.9080.18
627_R656_F0.9080.18
309_N381_Y0.9050.18
558_L648_V0.9050.18
76_L101_E0.9050.18
9_S44_A0.9040.18
356_A390_A0.9030.18
124_W144_L0.8990.18
282_E542_T0.8950.18
301_I323_V0.8950.18
178_A456_S0.8950.18
443_A497_T0.8940.18
459_E633_K0.8930.18
6_S10_G0.8890.18
417_C452_L0.8880.18
432_P505_M0.8870.18
569_K573_A0.8810.18
358_C382_C0.8800.18
224_S445_T0.8800.18
389_P393_A0.8790.18
145_T497_T0.8780.18
572_A658_Q0.8780.18
237_G625_Q0.8770.18
100_I645_P0.8770.18
144_L491_K0.8760.18
184_T624_I0.8760.18
576_I648_V0.8760.18
76_L82_F0.8750.18
15_G101_E0.8750.18
313_D317_A0.8740.18
578_G644_K0.8720.18
339_N490_V0.8700.18
49_I453_N0.8680.18
603_V672_V0.8650.17
413_L536_P0.8630.17
143_L499_V0.8580.17
284_V322_V0.8570.17
74_H200_S0.8550.17
185_A490_V0.8550.17
67_M207_A0.8540.17
588_L653_V0.8540.17
31_L467_L0.8530.17
544_R553_V0.8520.17
323_V370_A0.8510.17
7_F179_I0.8510.17
153_H282_E0.8500.17
19_S38_G0.8500.17
207_A246_I0.8500.17
24_H237_G0.8480.17
148_S497_T0.8480.17
543_P623_T0.8480.17
153_H542_T0.8480.17
553_V620_P0.8470.17
554_N562_H0.8470.17
291_A336_A0.8440.17
544_R549_E0.8440.17
189_L195_K0.8430.17
58_A146_S0.8430.17
45_R539_S0.8420.17
615_I644_K0.8420.17
603_V636_K0.8410.17
663_V672_V0.8410.17
416_A438_F0.8410.17
530_Y633_K0.8400.17
187_A401_A0.8380.17
82_F194_V0.8370.17
385_P404_M0.8370.17
54_P57_R0.8330.17
87_A328_A0.8330.17
252_P549_E0.8320.17
7_F523_R0.8310.17
96_S281_R0.8310.17
333_K627_R0.8310.17
247_V499_V0.8300.17
668_I672_V0.8300.17
116_R280_I0.8290.17
560_G620_P0.8280.17
123_L440_A0.8240.16
10_G189_L0.8220.16
572_A612_L0.8210.16
443_A451_I0.8200.16
97_W349_K0.8200.16
264_V438_F0.8190.16
578_G646_T0.8180.16
168_L229_T0.8160.16
212_C255_M0.8140.16
79_K83_Y0.8130.16
600_V604_I0.8120.16
549_E562_H0.8110.16
524_I528_R0.8110.16
575_S668_I0.8100.16
301_I403_L0.8090.16
562_H645_P0.8090.16
62_I441_D0.8090.16
57_R426_T0.8080.16
467_L489_A0.8060.16
285_R456_S0.8030.16
571_A666_Y0.8020.16
273_Q430_A0.8020.16
289_T332_V0.8000.16
616_E633_K0.7990.16
48_A52_G0.7970.16
66_A70_A0.7960.16
26_I393_A0.7940.16
553_V562_H0.7930.16
133_S471_V0.7930.16
279_F449_I0.7920.16
575_S636_K0.7910.16
381_Y559_S0.7860.16
385_P402_T0.7860.16
36_S211_I0.7860.16
81_R137_G0.7850.16
546_T621_G0.7840.16
633_K674_R0.7840.16
436_R453_N0.7830.16
242_V535_Q0.7800.16
35_T456_S0.7790.16
153_H653_V0.7780.15
120_D635_L0.7780.15
139_A501_G0.7770.15
24_H511_K0.7770.15
22_I338_V0.7750.15
491_K540_L0.7750.15
241_R622_D0.7730.15
315_L493_Y0.7720.15
8_L630_C0.7710.15
18_R21_L0.7700.15
229_T252_P0.7690.15
185_A188_Q0.7680.15
24_H104_I0.7670.15
133_S237_G0.7640.15
570_I575_S0.7630.15
115_S262_C0.7620.15
610_E650_E0.7620.15
89_T287_M0.7600.15
545_R612_L0.7590.15
184_T611_S0.7590.15
616_E653_V0.7590.15
62_I65_A0.7570.15
67_M202_L0.7570.15
207_A404_M0.7570.15
349_K380_L0.7560.15
549_E648_V0.7560.15
94_A98_V0.7540.15
79_K97_W0.7540.15
570_I648_V0.7530.15
610_E642_E0.7520.15
345_D450_Q0.7510.15
576_I636_K0.7500.15
455_E504_T0.7500.15
241_R324_V0.7490.15
513_W588_L0.7490.15
559_S562_H0.7480.15
120_D171_T0.7470.15
385_P405_P0.7460.15
452_L457_A0.7460.15
586_F648_V0.7450.15
85_L620_P0.7440.15
29_E88_Q0.7420.15
100_I189_L0.7420.15
352_I356_A0.7410.15
574_E645_P0.7410.15
572_A622_D0.7400.15
46_Q216_G0.7390.15
139_A456_S0.7380.15
19_S439_I0.7380.15
190_T199_D0.7360.15
549_E567_M0.7340.15
68_L509_I0.7330.15
658_Q666_Y0.7330.15
153_H227_V0.7320.15
35_T417_C0.7310.14
538_D633_K0.7310.14
113_L144_L0.7310.14
541_L625_Q0.7290.14
82_F192_A0.7290.14
484_L587_V0.7280.14
336_A414_Q0.7280.14
123_L674_R0.7270.14
264_V623_T0.7260.14
600_V612_L0.7260.14
487_L491_K0.7250.14
578_G661_T0.7250.14
73_K115_S0.7250.14
652_A666_Y0.7240.14
143_L321_K0.7230.14
100_I193_M0.7230.14
425_G428_V0.7220.14
471_V494_M0.7220.14
570_I574_E0.7220.14
118_L607_Y0.7210.14
347_Q376_P0.7210.14
60_T122_T0.7200.14
172_W255_M0.7200.14
57_R333_K0.7180.14
322_V332_V0.7180.14
4_L187_A0.7180.14
531_F588_L0.7160.14
128_E280_I0.7160.14
285_R315_L0.7150.14
237_G257_A0.7140.14
101_E250_S0.7140.14
619_K644_K0.7140.14
394_T506_L0.7140.14
80_E100_I0.7130.14
544_R557_C0.7130.14
417_C453_N0.7130.14
531_F653_V0.7130.14
268_D674_R0.7130.14
124_W272_D0.7120.14
82_F168_L0.7110.14
61_F379_L0.7100.14
129_L673_A0.7100.14
301_I453_N0.7090.14
301_I627_R0.7080.14
85_L630_C0.7060.14
24_H255_M0.7060.14
605_A673_A0.7050.14
607_Y610_E0.7050.14
513_W635_L0.7050.14
590_A645_P0.7040.14
116_R130_I0.7030.14
283_V630_C0.7030.14
137_G459_E0.7030.14
607_Y613_R0.7030.14
7_F316_V0.7030.14
544_R574_E0.7010.14
141_R436_R0.7010.14
484_L547_M0.7010.14
310_A567_M0.7000.14
176_M227_V0.7000.14
554_N648_V0.7000.14
616_E644_K0.6990.14
118_L665_L0.6980.14
176_M211_I0.6980.14
643_E648_V0.6980.14
554_N650_E0.6970.14
370_A391_V0.6970.14
124_W242_V0.6960.14
63_E453_N0.6950.14
360_I378_T0.6950.14
229_T254_T0.6940.14
186_T338_V0.6910.14
605_A622_D0.6900.14
382_C402_T0.6900.14
520_E630_C0.6900.14
193_M197_I0.6890.14
622_D663_V0.6880.14
350_V378_T0.6880.14
643_E659_H0.6870.14
553_V557_C0.6860.14
662_P665_L0.6860.14
78_E413_L0.6860.14
185_A499_V0.6860.14
624_I662_P0.6850.14
610_E643_E0.6840.14
123_L432_P0.6830.14
62_I581_V0.6810.14
66_A630_C0.6800.13
24_H27_S0.6790.13
545_R605_A0.6790.13
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456_S501_G0.6780.13
312_S381_Y0.6780.13
207_A271_P0.6770.13
394_T546_T0.6770.13
178_A633_K0.6770.13
191_Q409_Q0.6760.13
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274_P455_E0.6660.13
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336_A664_A0.6620.13
260_L446_H0.6610.13
215_A345_D0.6600.13
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530_Y536_P0.6450.13
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239_M264_V0.6430.13
189_L193_M0.6430.13
348_E352_I0.6430.13
126_E655_V0.6420.13
30_A33_E0.6420.13
375_F579_E0.6420.13
153_H172_W0.6410.13
73_K587_V0.6400.13
225_Q402_T0.6400.13
200_S449_I0.6400.13
615_I650_E0.6380.13
338_V533_E0.6370.13
438_F509_I0.6370.13
360_I444_R0.6370.13
143_L302_I0.6360.13
45_R499_V0.6350.13
411_H457_A0.6350.13
123_L633_K0.6350.13
263_C425_G0.6340.13
598_A601_G0.6340.13
369_S408_N0.6330.13
350_V393_A0.6320.13
636_K643_E0.6310.13
98_V465_S0.6310.13
650_E667_S0.6310.13
578_G590_A0.6310.13
119_P186_T0.6310.13
96_S338_V0.6300.13
362_L376_P0.6300.13
145_T148_S0.6300.13
94_A97_W0.6290.13
587_V607_Y0.6290.13
345_D632_R0.6290.13
554_N615_I0.6280.13
425_G438_F0.6280.13
350_V573_A0.6280.13
222_L578_G0.6280.13
311_V336_A0.6270.13
507_A514_V0.6270.13
568_D601_G0.6270.13
266_G314_A0.6270.13
107_L468_P0.6260.12
590_A671_L0.6260.12
137_G202_L0.6260.12
67_M70_A0.6240.12
152_V220_D0.6240.12
574_E658_Q0.6240.12
34_V54_P0.6230.12
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254_T257_A0.6220.12
252_P553_V0.6210.12
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311_V509_I0.6200.12
225_Q446_H0.6190.12
219_L222_L0.6180.12
184_T345_D0.6170.12
554_N559_S0.6170.12
269_V587_V0.6170.12
326_D394_T0.6160.12
553_V650_E0.6160.12
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247_V453_N0.6150.12
15_G255_M0.6140.12
168_L611_S0.6130.12
570_I599_G0.6130.12
172_W237_G0.6130.12
78_E93_R0.6120.12
184_T661_T0.6120.12
590_A624_I0.6120.12
120_D531_F0.6110.12
45_R77_S0.6110.12
646_T652_A0.6100.12
13_Q17_G0.6100.12
544_R570_I0.6100.12
208_I364_G0.6090.12
211_I662_P0.6080.12
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191_Q199_D0.5990.12
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27_S513_W0.5990.12
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417_C652_A0.5950.12
301_I630_C0.5950.12
49_I70_A0.5950.12
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619_K646_T0.5930.12
645_P648_V0.5910.12
574_E648_V0.5910.12
574_E657_N0.5900.12
125_P510_S0.5900.12
153_H171_T0.5870.12
620_P671_L0.5860.12
93_R101_E0.5850.12
170_P666_Y0.5850.12
358_C402_T0.5840.12
7_F29_E0.5840.12
76_L97_W0.5830.12
505_M530_Y0.5830.12
13_Q42_A0.5820.12
303_V311_V0.5800.12
586_F650_E0.5800.12
612_L648_V0.5800.12
580_R601_G0.5790.12
554_N668_I0.5790.12
586_F646_T0.5790.12
82_F247_V0.5780.12
611_S667_S0.5780.12
215_A529_K0.5780.12
197_I458_K0.5770.12
550_A553_V0.5760.12
579_E650_E0.5750.12
452_L538_D0.5740.12
658_Q671_L0.5740.12
263_C515_R0.5730.12
553_V668_I0.5730.12
45_R146_S0.5720.12
280_I311_V0.5720.12
218_L221_H0.5720.12
44_A150_V0.5700.12
59_M193_M0.5690.12
6_S382_C0.5690.12
125_P471_V0.5680.11
636_K668_I0.5680.11
19_S345_D0.5670.11
557_C570_I0.5670.11
49_I120_D0.5660.11
111_A487_L0.5660.11
452_L470_L0.5660.11
123_L237_G0.5650.11
282_E633_K0.5650.11
250_S404_M0.5650.11
432_P453_N0.5640.11
571_A600_V0.5630.11
601_G664_A0.5630.11
247_V443_A0.5620.11
123_L171_T0.5610.11
185_A339_N0.5590.11
576_I646_T0.5580.11
361_R381_Y0.5580.11
212_C660_Q0.5580.11
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450_Q460_S0.5570.11
567_M579_E0.5570.11
6_S188_Q0.5570.11
275_E454_E0.5570.11
85_L168_L0.5560.11
172_W674_R0.5560.11
25_A86_S0.5550.11
153_H385_P0.5550.11
282_E385_P0.5540.11
63_E128_E0.5530.11
375_F615_I0.5530.11
245_N269_V0.5530.11
189_L202_L0.5530.11
529_K581_V0.5530.11
144_L229_T0.5520.11
351_N573_A0.5520.11
124_W305_Q0.5520.11
100_I484_L0.5510.11
214_S515_R0.5510.11
549_E668_I0.5510.11
267_E409_Q0.5500.11
153_H285_R0.5490.11
518_K623_T0.5490.11
257_A467_L0.5490.11
7_F12_W0.5490.11
70_A264_V0.5480.11
104_I618_V0.5480.11
249_K404_M0.5480.11
257_A428_V0.5470.11
558_L615_I0.5460.11
211_I243_Q0.5450.11
279_F283_V0.5450.11
49_I179_I0.5450.11
363_G366_A0.5450.11
143_L219_L0.5440.11
216_G449_I0.5440.11
562_H648_V0.5430.11
553_V590_A0.5430.11
252_P513_W0.5420.11
283_V287_M0.5420.11
185_A616_E0.5420.11
205_E568_D0.5390.11
587_V671_L0.5390.11
351_N673_A0.5390.11
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190_T370_A0.5380.11
512_Q515_R0.5380.11
269_V484_L0.5380.11
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635_L674_R0.5360.11
302_I610_E0.5360.11
48_A458_K0.5360.11
576_I586_F0.5360.11
152_V587_V0.5360.11
7_F48_A0.5350.11
169_A424_A0.5350.11
559_S636_K0.5350.11
93_R453_N0.5340.11
529_K671_L0.5340.11
471_V497_T0.5330.11
246_I287_M0.5330.11
227_V404_M0.5330.11
135_E458_K0.5320.11
198_V202_L0.5320.11
357_G610_E0.5320.11
487_L540_L0.5320.11
665_L668_I0.5310.11
539_S579_E0.5310.11
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321_K333_K0.5300.11
622_D672_V0.5290.11
657_N663_V0.5290.11
312_S359_E0.5290.11
36_S459_E0.5290.11
567_M610_E0.5280.11
43_A347_Q0.5280.11
379_L673_A0.5270.11
124_W634_T0.5270.11
52_G235_A0.5270.11
364_G489_A0.5270.11
575_S622_D0.5270.11
83_Y96_S0.5270.11
340_A662_P0.5270.11
32_W127_D0.5260.11
122_T662_P0.5260.11
513_W579_E0.5260.11
636_K644_K0.5260.11
224_S643_E0.5250.11
67_M110_Y0.5250.11
417_C470_L0.5250.11
196_S202_L0.5240.11
313_D418_A0.5240.11
262_C328_A0.5230.11
132_L471_V0.5230.11
274_P330_E0.5220.11
309_N408_N0.5220.11
207_A338_V0.5220.11
26_I336_A0.5210.11
436_R587_V0.5210.11
216_G223_D0.5210.11
14_S289_T0.5200.11
147_K558_L0.5200.11
536_P654_E0.5200.11
45_R129_L0.5200.11
147_K562_H0.5190.11
424_A484_L0.5190.11
37_E317_A0.5190.11
513_W653_V0.5190.11
382_C385_P0.5190.11
115_S121_D0.5180.11
221_H441_D0.5180.11
468_P552_I0.5170.11
46_Q360_I0.5170.11
562_H575_S0.5160.11
668_I671_L0.5150.11
345_D353_L0.5150.11
317_A320_Q0.5150.11
355_A358_C0.5150.11
49_I405_P0.5140.11
49_I320_Q0.5130.11
136_G311_V0.5120.11
272_D324_V0.5120.11
250_S405_P0.5110.11
587_V590_A0.5110.11
316_V660_Q0.5110.11
72_A468_P0.5110.11
173_L490_V0.5100.11
180_I603_V0.5090.11
549_E575_S0.5090.11
9_S611_S0.5080.11
609_L624_I0.5080.11
31_L353_L0.5070.11
89_T336_A0.5070.11
572_A667_S0.5070.11
187_A343_R0.5070.11
199_D411_H0.5060.10
82_F211_I0.5060.10
568_D580_R0.5050.10
172_W452_L0.5040.10
544_R558_L0.5040.10
134_K411_H0.5040.10
315_L379_L0.5040.10
403_L413_L0.5030.10
612_L652_A0.5030.10
667_S674_R0.5030.10
170_P586_F0.5030.10
147_K404_M0.5020.10
212_C451_I0.5020.10
107_L271_P0.5010.10
237_G603_V0.5010.10
164_M283_V0.5000.10
309_N362_L0.5000.10
605_A646_T0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2y53A 2 0.7533 100 0.671 Contact Map
3ek1A 5 0.6902 100 0.694 Contact Map
4pz2A 4 0.7004 100 0.695 Contact Map
1a4sA 4 0.7004 100 0.695 Contact Map
4pxlA 4 0.699 100 0.695 Contact Map
4wj9A 4 0.6975 100 0.695 Contact Map
1wndA 4 0.6858 100 0.696 Contact Map
4nm9A 2 0.7107 100 0.696 Contact Map
4yweA 5 0.6872 100 0.696 Contact Map
4qf6A 4 0.6902 100 0.697 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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