EUTE - ECOLI - GREMLIN Contacts

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EUTE - Ethanolamine utilization protein EutE

UniProt:	P77445	Sequences: MNQQDIEQVVKAVLLKMQSSDTPSAAVHEMGVFASLDDAVAAAKVAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTPGVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAPHPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGEAVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGTVSRDWVGRDAGKIAAAIGLKVPQETRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHHTAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14185
Length:	467 (438)
Sequences:	36342 (21939)
Seq/√Len:	1048.3

ECOLI - EUTE PUUC BETB GABD FEAB ALDB ABDH ALDA ASTD SAD PUTA PROA PAAZ ADHE
BACSU - ROCA2 ROCA ALDH4 ALDH1 ALDH5 IOLA ALDY GABD BETB ALDH3 ALDH2 PROA
HALSA - Q9HQZ2 Q9HMJ6 Q9HRB5 Q9HR91
SULSO - Q97YT9 GAPN KGSDH Q97XS9 Q97XA5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
279_D	374_A	5.277	1.00
279_D	372_R	3.315	1.00
251_A	288_L	3.266	1.00
282_A	372_R	3.034	1.00
353_T	356_H	2.867	1.00
44_K	208_G	2.866	1.00
15_L	27_V	2.841	1.00
246_E	278_V	2.837	1.00
315_E	319_G	2.740	1.00
255_Q	292_Q	2.659	1.00
170_R	173_T	2.605	1.00
286_M	370_V	2.594	1.00
246_E	280_S	2.510	1.00
68_E	99_R	2.501	1.00
337_I	345_T	2.477	1.00
70_H	73_D	2.465	1.00
398_S	404_M	2.383	1.00
180_V	186_E	2.372	1.00
15_L	24_S	2.324	1.00
44_K	210_G	2.320	1.00
303_Q	306_Q	2.305	1.00
32_V	35_S	2.280	1.00
63_I	175_L	2.275	1.00
71_A	92_A	2.202	1.00
331_G	351_E	2.144	1.00
376_V	403_N	2.129	1.00
322_S	338_G	2.087	1.00
201_Q	205_K	2.075	1.00
387_E	435_T	2.060	1.00
124_A	456_R	2.050	1.00
163_A	314_D	2.040	1.00
312_N	321_V	2.031	1.00
205_K	227_H	2.026	1.00
290_E	294_A	2.002	1.00
406_Q	410_A	1.977	1.00
242_V	257_I	1.970	1.00
59_A	184_G	1.948	1.00
73_D	170_R	1.948	1.00
284_E	288_L	1.945	1.00
333_I	350_V	1.932	1.00
66_A	181_A	1.883	1.00
247_T	403_N	1.875	1.00
37_D	202_R	1.868	1.00
326_V	332_K	1.856	1.00
222_E	435_T	1.856	1.00
276_I	382_L	1.856	1.00
41_A	208_G	1.838	1.00
223_A	226_K	1.835	1.00
349_F	358_F	1.812	1.00
376_V	406_Q	1.805	1.00
412_D	434_T	1.805	1.00
66_A	69_K	1.800	1.00
276_I	379_A	1.769	1.00
278_V	373_V	1.763	1.00
359_A	371_V	1.751	1.00
354_A	382_L	1.747	1.00
123_N	453_V	1.733	1.00
123_N	450_R	1.731	1.00
37_D	41_A	1.729	1.00
66_A	174_L	1.718	1.00
293_H	348_L	1.716	1.00
357_P	361_T	1.707	1.00
77_L	170_R	1.697	1.00
172_I	191_T	1.671	1.00
378_D	381_A	1.662	1.00
290_E	333_I	1.658	1.00
257_I	285_L	1.654	1.00
24_S	27_V	1.637	1.00
282_A	286_M	1.619	1.00
332_K	349_F	1.618	1.00
47_Q	51_K	1.616	1.00
287_R	291_G	1.601	1.00
275_L	368_L	1.597	1.00
61_A	99_R	1.597	1.00
374_A	378_D	1.596	1.00
195_P	198_E	1.594	1.00
262_S	293_H	1.586	1.00
250_L	288_L	1.584	1.00
66_A	182_A	1.581	1.00
331_G	350_V	1.575	1.00
155_S	188_L	1.561	1.00
65_E	69_K	1.559	1.00
37_D	206_F	1.555	1.00
283_D	372_R	1.554	1.00
288_L	291_G	1.533	1.00
323_R	357_P	1.518	1.00
62_A	65_E	1.509	1.00
377_A	410_A	1.497	1.00
68_E	95_V	1.491	1.00
72_R	76_E	1.486	1.00
98_A	147_I	1.482	1.00
254_A	288_L	1.482	1.00
245_D	403_N	1.480	1.00
256_S	397_H	1.470	1.00
276_I	373_V	1.470	1.00
246_E	403_N	1.461	1.00
324_D	363_L	1.460	1.00
76_E	80_S	1.446	1.00
257_I	275_L	1.441	1.00
394_A	413_T	1.437	1.00
52_S	410_A	1.435	1.00
277_V	285_L	1.435	1.00
284_E	287_R	1.429	1.00
292_Q	295_V	1.427	1.00
70_H	181_A	1.427	1.00
13_V	27_V	1.426	1.00
65_E	99_R	1.424	1.00
131_S	156_V	1.407	1.00
104_V	107_L	1.405	1.00
79_V	89_D	1.402	1.00
326_V	329_D	1.400	1.00
282_A	350_V	1.399	1.00
35_S	38_D	1.394	1.00
122_E	409_N	1.383	1.00
318_K	322_S	1.383	1.00
297_L	306_Q	1.381	1.00
225_R	438_I	1.370	1.00
378_D	382_L	1.367	1.00
18_Q	21_D	1.365	1.00
70_H	170_R	1.364	1.00
17_M	24_S	1.361	1.00
321_V	365_M	1.356	1.00
245_D	373_V	1.352	1.00
201_Q	227_H	1.340	1.00
211_L	233_I	1.337	1.00
76_E	302_A	1.332	1.00
98_A	143_I	1.331	1.00
373_V	382_L	1.330	1.00
64_R	99_R	1.330	1.00
172_I	189_L	1.328	1.00
328_R	357_P	1.320	1.00
375_N	378_D	1.311	1.00
110_Q	444_E	1.310	1.00
12_A	30_M	1.303	1.00
47_Q	155_S	1.302	1.00
142_V	158_F	1.299	1.00
291_G	294_A	1.291	1.00
294_A	334_A	1.285	1.00
40_V	206_F	1.283	1.00
283_D	287_R	1.278	1.00
319_G	323_R	1.273	1.00
380_I	407_M	1.271	1.00
315_E	318_K	1.269	1.00
286_M	290_E	1.268	1.00
245_D	407_M	1.265	1.00
64_R	68_E	1.259	1.00
278_V	375_N	1.251	1.00
175_L	189_L	1.243	1.00
318_K	338_G	1.243	1.00
36_L	199_T	1.242	1.00
162_P	195_P	1.234	1.00
243_V	379_A	1.233	1.00
299_A	307_P	1.230	1.00
281_V	284_E	1.227	1.00
74_L	170_R	1.226	1.00
110_Q	445_G	1.225	1.00
278_V	281_V	1.223	1.00
300_E	303_Q	1.220	1.00
355_E	360_V	1.218	1.00
162_P	197_I	1.217	1.00
201_Q	223_A	1.215	1.00
444_E	450_R	1.208	1.00
289_M	368_L	1.207	1.00
187_N	190_V	1.205	1.00
30_M	195_P	1.200	1.00
40_V	208_G	1.197	1.00
33_F	202_R	1.196	1.00
354_A	385_K	1.190	1.00
285_L	289_M	1.189	1.00
297_L	308_V	1.185	1.00
120_L	405_N	1.183	1.00
63_I	174_L	1.183	1.00
41_A	45_V	1.182	1.00
408_A	458_C	1.177	1.00
53_V	59_A	1.169	1.00
123_N	455_L	1.169	1.00
79_V	301_Q	1.166	1.00
62_A	66_A	1.165	1.00
76_E	86_R	1.155	1.00
173_T	181_A	1.147	1.00
40_V	209_I	1.146	1.00
42_A	190_V	1.141	1.00
63_I	184_G	1.140	1.00
286_M	333_I	1.140	1.00
288_L	292_Q	1.138	1.00
220_V	223_A	1.137	1.00
377_A	406_Q	1.134	1.00
291_G	295_V	1.133	1.00
394_A	416_F	1.130	1.00
223_A	227_H	1.128	1.00
360_V	385_K	1.128	1.00
404_M	418_K	1.127	1.00
130_A	203_L	1.123	1.00
146_A	189_L	1.122	1.00
126_W	211_L	1.121	1.00
18_Q	300_E	1.118	1.00
225_R	232_L	1.116	1.00
242_V	272_E	1.116	1.00
330_A	349_F	1.113	1.00
219_A	223_A	1.113	1.00
296_K	309_L	1.113	1.00
341_V	344_E	1.112	1.00
63_I	98_A	1.112	1.00
131_S	213_V	1.109	1.00
360_V	387_E	1.106	1.00
243_V	407_M	1.102	1.00
286_M	350_V	1.097	1.00
239_N	273_K	1.095	1.00
169_Q	193_A	1.095	1.00
26_A	166_K	1.087	1.00
290_E	334_A	1.084	1.00
328_R	356_H	1.084	1.00
20_S	301_Q	1.080	1.00
74_L	174_L	1.078	1.00
137_N	268_I	1.075	1.00
202_R	206_F	1.075	1.00
377_A	381_A	1.073	1.00
70_H	174_L	1.067	1.00
14_L	30_M	1.066	1.00
61_A	103_G	1.061	1.00
249_D	399_R	1.060	1.00
440_T	454_R	1.057	1.00
380_I	410_A	1.057	1.00
243_V	383_A	1.054	1.00
335_A	347_L	1.052	1.00
146_A	156_V	1.051	1.00
376_V	407_M	1.051	1.00
321_V	367_V	1.050	1.00
445_G	450_R	1.046	1.00
130_A	209_I	1.044	1.00
400_N	403_N	1.033	1.00
431_E	440_T	1.027	1.00
46_A	155_S	1.021	1.00
225_R	229_N	1.020	1.00
48_Q	381_A	1.017	1.00
169_Q	191_T	1.011	1.00
126_W	231_R	1.006	1.00
373_V	379_A	1.005	1.00
249_D	252_R	1.004	1.00
445_G	455_L	0.996	1.00
329_D	356_H	0.990	1.00
173_T	180_V	0.989	1.00
122_E	458_C	0.986	1.00
48_Q	412_D	0.983	1.00
433_W	454_R	0.983	1.00
241_P	394_A	0.982	1.00
94_N	143_I	0.981	1.00
324_D	357_P	0.980	1.00
128_V	155_S	0.974	1.00
283_D	286_M	0.973	1.00
260_G	272_E	0.961	1.00
395_A	421_P	0.960	1.00
210_G	412_D	0.960	1.00
261_A	273_K	0.959	1.00
48_Q	52_S	0.956	1.00
326_V	349_F	0.955	1.00
30_M	198_E	0.954	1.00
352_T	356_H	0.952	1.00
73_D	76_E	0.951	1.00
322_S	325_W	0.947	1.00
251_A	284_E	0.944	1.00
44_K	48_Q	0.944	1.00
381_A	385_K	0.937	1.00
336_A	347_L	0.936	1.00
80_S	302_A	0.933	1.00
18_Q	80_S	0.932	1.00
252_R	256_S	0.932	1.00
128_V	209_I	0.922	1.00
250_L	254_A	0.919	1.00
129_V	211_L	0.919	1.00
258_V	292_Q	0.918	1.00
51_K	412_D	0.918	1.00
33_F	37_D	0.917	1.00
69_K	181_A	0.915	1.00
254_A	289_M	0.915	1.00
70_H	173_T	0.913	1.00
245_D	376_V	0.912	1.00
18_Q	23_P	0.912	1.00
119_T	428_L	0.902	1.00
231_R	454_R	0.902	1.00
36_L	130_A	0.902	1.00
82_T	164_A	0.899	1.00
57_Q	61_A	0.898	1.00
321_V	363_L	0.897	1.00
282_A	370_V	0.896	1.00
217_G	220_V	0.894	1.00
371_V	382_L	0.893	1.00
46_A	188_L	0.893	1.00
319_G	322_S	0.892	1.00
282_A	351_E	0.889	1.00
242_V	397_H	0.882	1.00
124_A	433_W	0.882	1.00
124_A	409_N	0.880	1.00
379_A	382_L	0.879	1.00
212_L	228_T	0.879	1.00
66_A	70_H	0.878	1.00
61_A	105_E	0.878	1.00
254_A	285_L	0.875	1.00
58_L	62_A	0.874	1.00
354_A	371_V	0.872	1.00
126_W	154_N	0.872	1.00
94_N	139_A	0.872	1.00
254_A	292_Q	0.871	1.00
253_A	257_I	0.869	1.00
33_F	198_E	0.869	1.00
212_L	224_A	0.869	1.00
396_M	407_M	0.868	1.00
373_V	378_D	0.865	1.00
405_N	409_N	0.864	1.00
225_R	228_T	0.860	1.00
245_D	398_S	0.856	1.00
163_A	316_R	0.855	1.00
330_A	356_H	0.854	1.00
194_N	199_T	0.852	1.00
57_Q	105_E	0.850	1.00
38_D	42_A	0.849	1.00
42_A	187_N	0.848	1.00
222_E	226_K	0.848	1.00
394_A	411_I	0.848	1.00
339_L	345_T	0.847	1.00
221_V	236_G	0.845	1.00
50_L	188_L	0.844	1.00
244_V	285_L	0.842	1.00
380_I	384_V	0.842	1.00
61_A	102_P	0.840	1.00
158_F	168_S	0.837	1.00
52_S	409_N	0.837	1.00
84_M	90_K	0.836	1.00
14_L	195_P	0.836	1.00
34_A	38_D	0.832	1.00
325_W	367_V	0.831	1.00
428_L	457_R	0.830	1.00
126_W	454_R	0.828	1.00
84_M	88_E	0.823	1.00
67_G	94_N	0.821	1.00
60_I	151_A	0.821	1.00
45_V	48_Q	0.819	1.00
169_Q	173_T	0.818	1.00
240_P	273_K	0.818	1.00
148_S	448_S	0.818	1.00
22_T	342_P	0.816	1.00
34_A	37_D	0.816	1.00
62_A	182_A	0.814	1.00
287_R	290_E	0.812	1.00
57_Q	102_P	0.812	1.00
294_A	345_T	0.810	1.00
254_A	258_V	0.810	1.00
197_I	201_Q	0.808	1.00
142_V	146_A	0.808	1.00
31_G	35_S	0.805	1.00
204_F	224_A	0.804	1.00
87_V	308_V	0.804	1.00
204_F	227_H	0.801	1.00
401_I	404_M	0.801	1.00
130_A	200_A	0.801	1.00
152_A	453_V	0.800	1.00
413_T	416_F	0.799	1.00
59_A	182_A	0.799	1.00
38_D	41_A	0.798	1.00
82_T	313_I	0.797	1.00
79_V	86_R	0.797	1.00
31_G	39_A	0.797	1.00
221_V	234_A	0.797	1.00
43_A	190_V	0.794	1.00
184_G	189_L	0.792	1.00
145_N	441_P	0.789	1.00
214_V	220_V	0.787	1.00
253_A	285_L	0.786	1.00
131_S	145_N	0.784	1.00
149_L	156_V	0.783	1.00
75_A	79_V	0.783	1.00
289_M	348_L	0.782	1.00
48_Q	51_K	0.778	1.00
298_T	339_L	0.777	1.00
61_A	65_E	0.776	1.00
324_D	361_T	0.775	1.00
86_R	302_A	0.774	1.00
143_I	171_A	0.774	1.00
241_P	383_A	0.773	1.00
160_P	193_A	0.773	1.00
204_F	212_L	0.773	1.00
25_A	80_S	0.770	1.00
226_K	229_N	0.768	1.00
45_V	49_G	0.767	1.00
296_K	308_V	0.765	1.00
130_A	212_L	0.764	1.00
335_A	345_T	0.763	1.00
293_H	334_A	0.761	1.00
75_A	86_R	0.760	1.00
80_S	166_K	0.758	1.00
114_G	119_T	0.753	1.00
184_G	188_L	0.752	1.00
250_L	281_V	0.751	1.00
299_A	303_Q	0.751	1.00
325_W	349_F	0.747	1.00
316_R	319_G	0.747	1.00
154_N	453_V	0.747	1.00
278_V	376_V	0.746	1.00
139_A	167_V	0.745	1.00
351_E	372_R	0.742	1.00
64_R	102_P	0.742	1.00
36_L	202_R	0.740	1.00
258_V	289_M	0.739	1.00
49_G	53_V	0.739	1.00
17_M	22_T	0.739	1.00
251_A	292_Q	0.734	1.00
218_E	435_T	0.734	1.00
119_T	457_R	0.732	1.00
194_N	200_A	0.730	1.00
68_E	71_A	0.730	1.00
67_G	95_V	0.728	1.00
197_I	223_A	0.727	1.00
290_E	293_H	0.725	1.00
78_A	81_E	0.724	1.00
339_L	343_Q	0.724	1.00
303_Q	307_P	0.719	1.00
18_Q	302_A	0.719	1.00
277_V	281_V	0.718	1.00
142_V	168_S	0.714	1.00
245_D	278_V	0.714	1.00
163_A	313_I	0.713	1.00
158_F	189_L	0.712	1.00
126_W	210_G	0.711	1.00
36_L	40_V	0.710	1.00
68_E	92_A	0.710	1.00
200_A	204_F	0.710	1.00
315_E	338_G	0.707	1.00
50_L	59_A	0.707	1.00
318_K	339_L	0.706	1.00
231_R	451_T	0.706	1.00
375_N	381_A	0.706	1.00
354_A	359_A	0.705	1.00
22_T	315_E	0.704	1.00
228_T	232_L	0.701	1.00
300_E	307_P	0.701	1.00
334_A	348_L	0.700	1.00
352_T	359_A	0.700	1.00
77_L	166_K	0.700	1.00
293_H	296_K	0.699	1.00
275_L	285_L	0.699	1.00
322_S	326_V	0.696	1.00
44_K	47_Q	0.694	1.00
202_R	205_K	0.694	1.00
276_I	359_A	0.692	1.00
376_V	380_I	0.691	1.00
399_R	402_E	0.691	1.00
104_V	151_A	0.688	1.00
74_L	139_A	0.686	1.00
298_T	309_L	0.685	1.00
51_K	410_A	0.684	1.00
317_G	320_T	0.684	1.00
43_A	155_S	0.683	1.00
339_L	342_P	0.683	1.00
332_K	335_A	0.683	1.00
265_N	309_L	0.683	1.00
198_E	201_Q	0.683	1.00
175_L	184_G	0.680	1.00
247_T	398_S	0.679	1.00
244_V	253_A	0.677	1.00
382_L	385_K	0.674	1.00
157_I	190_V	0.674	1.00
142_V	171_A	0.673	1.00
162_P	320_T	0.673	1.00
65_E	68_E	0.672	1.00
257_I	289_M	0.671	1.00
312_N	317_G	0.671	1.00
37_D	208_G	0.669	1.00
73_D	173_T	0.668	1.00
326_V	330_A	0.667	1.00
133_T	142_V	0.666	1.00
349_F	352_T	0.665	1.00
13_V	29_E	0.664	1.00
401_I	405_N	0.663	1.00
51_K	125_P	0.663	1.00
314_D	317_G	0.662	1.00
276_I	354_A	0.657	1.00
450_R	453_V	0.657	1.00
49_G	52_S	0.656	1.00
170_R	174_L	0.656	1.00
72_R	86_R	0.655	1.00
404_M	408_A	0.652	1.00
350_V	372_R	0.652	1.00
29_E	193_A	0.650	1.00
332_K	347_L	0.650	1.00
145_N	213_V	0.650	1.00
258_V	296_K	0.648	1.00
225_R	234_A	0.646	1.00
12_A	198_E	0.646	1.00
42_A	186_E	0.644	1.00
31_G	192_V	0.644	1.00
250_L	284_E	0.643	1.00
320_T	323_R	0.642	1.00
233_I	451_T	0.642	1.00
450_R	455_L	0.641	1.00
247_T	399_R	0.640	1.00
408_A	418_K	0.638	1.00
412_D	433_W	0.637	1.00
363_L	367_V	0.637	1.00
119_T	459_V	0.636	1.00
79_V	302_A	0.635	1.00
48_Q	410_A	0.634	1.00
50_L	150_I	0.633	1.00
146_A	158_F	0.632	1.00
195_P	199_T	0.630	1.00
23_P	342_P	0.630	1.00
289_M	370_V	0.629	1.00
118_L	405_N	0.627	1.00
398_S	403_N	0.625	1.00
41_A	44_K	0.625	1.00
91_F	95_V	0.625	1.00
316_R	320_T	0.624	1.00
28_H	165_K	0.624	1.00
76_E	79_V	0.623	1.00
429_G	432_G	0.621	1.00
39_A	192_V	0.620	1.00
162_P	223_A	0.619	1.00
16_K	26_A	0.619	1.00
252_R	255_Q	0.619	1.00
71_A	75_A	0.618	1.00
252_R	399_R	0.616	1.00
120_L	458_C	0.615	1.00
380_I	406_Q	0.615	1.00
155_S	190_V	0.615	1.00
16_K	81_E	0.614	1.00
84_M	137_N	0.612	1.00
172_I	180_V	0.612	1.00
59_A	183_G	0.609	1.00
396_M	404_M	0.605	1.00
380_I	411_I	0.605	1.00
46_A	49_G	0.604	1.00
67_G	98_A	0.604	1.00
242_V	395_A	0.604	1.00
78_A	167_V	0.601	1.00
33_F	205_K	0.601	1.00
66_A	183_G	0.600	1.00
270_A	425_G	0.599	1.00
51_K	124_A	0.598	1.00
247_T	400_N	0.598	1.00
139_A	171_A	0.596	1.00
402_E	405_N	0.596	1.00
92_A	95_V	0.595	1.00
277_V	370_V	0.595	1.00
277_V	282_A	0.595	1.00
260_G	421_P	0.594	1.00
242_V	275_L	0.593	1.00
352_T	358_F	0.592	1.00
67_G	139_A	0.589	1.00
211_L	451_T	0.589	1.00
25_A	166_K	0.588	1.00
55_M	151_A	0.586	1.00
67_G	171_A	0.585	1.00
129_V	154_N	0.582	1.00
268_I	271_D	0.582	1.00
298_T	308_V	0.582	1.00
140_A	144_N	0.582	1.00
402_E	406_Q	0.580	1.00
78_A	90_K	0.577	1.00
290_E	348_L	0.576	1.00
336_A	345_T	0.576	1.00
416_F	456_R	0.575	1.00
218_E	222_E	0.575	1.00
122_E	456_R	0.574	1.00
340_K	343_Q	0.574	1.00
171_A	175_L	0.573	1.00
354_A	381_A	0.573	1.00
250_L	253_A	0.567	1.00
43_A	157_I	0.567	1.00
415_I	424_A	0.566	1.00
63_I	66_A	0.566	1.00
16_K	165_K	0.566	1.00
275_L	370_V	0.566	1.00
42_A	46_A	0.565	1.00
152_A	449_A	0.565	1.00
328_R	355_E	0.564	1.00
246_E	373_V	0.563	1.00
396_M	418_K	0.557	1.00
261_A	368_L	0.556	1.00
67_G	74_L	0.556	1.00
379_A	383_A	0.555	1.00
128_V	210_G	0.553	1.00
131_S	146_A	0.553	1.00
279_D	282_A	0.553	1.00
59_A	63_I	0.552	1.00
248_A	253_A	0.551	1.00
250_L	285_L	0.550	1.00
44_K	128_V	0.549	1.00
84_M	89_D	0.549	1.00
240_P	391_H	0.549	1.00
376_V	410_A	0.548	1.00
417_V	420_G	0.548	1.00
93_K	140_A	0.547	1.00
272_E	395_A	0.546	1.00
12_A	32_V	0.546	1.00
64_R	98_A	0.541	1.00
28_H	166_K	0.541	1.00
130_A	157_I	0.540	1.00
383_A	411_I	0.539	1.00
359_A	382_L	0.539	1.00
411_I	416_F	0.538	1.00
337_I	340_K	0.536	1.00
129_V	156_V	0.535	1.00
90_K	137_N	0.535	1.00
162_P	219_A	0.534	1.00
130_A	204_F	0.533	1.00
78_A	89_D	0.533	1.00
219_A	316_R	0.533	1.00
254_A	281_V	0.532	1.00
412_D	454_R	0.531	1.00
108_S	111_V	0.529	1.00
438_I	454_R	0.528	1.00
117_G	420_G	0.528	1.00
333_I	351_E	0.528	1.00
264_D	268_I	0.528	1.00
289_M	293_H	0.527	1.00
101_T	148_S	0.527	1.00
150_I	189_L	0.525	1.00
43_A	128_V	0.525	1.00
262_S	296_K	0.525	1.00
39_A	190_V	0.524	1.00
82_T	264_D	0.524	1.00
251_A	291_G	0.523	1.00
330_A	352_T	0.522	1.00
381_A	410_A	0.522	1.00
22_T	344_E	0.521	1.00
91_F	139_A	0.521	1.00
136_T	364_M	0.520	1.00
354_A	360_V	0.520	1.00
30_M	162_P	0.518	1.00
132_V	224_A	0.518	1.00
64_R	95_V	0.517	1.00
150_I	184_G	0.517	1.00
328_R	353_T	0.517	1.00
39_A	43_A	0.516	1.00
62_A	183_G	0.516	1.00
75_A	91_F	0.516	1.00
325_W	347_L	0.515	1.00
332_K	336_A	0.515	1.00
391_H	417_V	0.515	1.00
241_P	413_T	0.515	1.00
407_M	411_I	0.514	1.00
433_W	440_T	0.514	1.00
11_K	35_S	0.513	1.00
129_V	213_V	0.513	1.00
71_A	95_V	0.511	1.00
165_K	193_A	0.510	1.00
16_K	25_A	0.510	1.00
320_T	324_D	0.509	1.00
55_M	105_E	0.507	1.00
287_R	294_A	0.507	1.00
75_A	89_D	0.507	1.00
201_Q	204_F	0.506	1.00
58_L	61_A	0.505	1.00
58_L	99_R	0.503	1.00
326_V	337_I	0.502	1.00
77_L	167_V	0.501	1.00
324_D	358_F	0.501	1.00
232_L	438_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4o5hA	4	0.9722	100	0.066	Contact Map
4pxlA	4	0.9807	100	0.068	Contact Map
3ek1A	5	0.9743	100	0.068	Contact Map
4yweA	5	0.97	100	0.069	Contact Map
4qf6A	4	0.9722	100	0.071	Contact Map
2o2pA	5	0.97	100	0.072	Contact Map
4lihA	5	0.9657	100	0.072	Contact Map
4pz2A	4	0.9807	100	0.074	Contact Map
4wj9A	4	0.9807	100	0.074	Contact Map
1a4sA	4	0.9786	100	0.075	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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