GREMLIN Database
PTFX1 - Multiphosphoryl transfer protein 1
UniProt: P77439 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14151
Length: 831 (663)
Sequences: 748 (511)
Seq/√Len: 19.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
287_G329_L7.8151.00
602_H630_D7.5551.00
509_L554_E6.3941.00
433_A438_I6.3411.00
480_R517_K5.9061.00
595_Q599_T5.8111.00
266_I287_G4.6861.00
419_E488_R4.4591.00
508_I555_V3.9821.00
569_L593_M3.9771.00
597_I608_V3.8141.00
266_I329_L3.7671.00
610_I629_L3.7641.00
609_G631_E3.7301.00
661_A673_L3.6721.00
545_C593_M3.6571.00
560_I597_I3.5061.00
483_L515_I3.3561.00
311_L331_A3.3471.00
512_K554_E3.3211.00
82_Y87_F3.2611.00
419_E481_T3.2511.00
154_R209_G3.1540.99
131_L327_A3.1490.99
517_K521_E3.1400.99
503_H543_S3.1060.99
469_V511_V3.1010.99
376_K651_S3.0420.99
480_R518_A3.0360.99
518_A521_E3.0230.99
373_R650_D3.0080.99
576_N579_V3.0070.99
73_E77_R2.9470.99
311_L336_L2.8730.99
30_Q71_D2.8250.99
622_P654_C2.7130.98
616_G642_V2.7050.98
466_Y474_E2.6950.98
539_V544_V2.6680.98
57_T63_C2.6660.98
439_I609_G2.6520.98
451_I455_N2.6420.98
31_S71_D2.5740.98
390_A394_F2.5510.98
8_C57_T2.5360.97
487_L515_I2.5090.97
8_C63_C2.4810.97
496_Q534_T2.4180.97
460_E575_N2.4170.97
666_S669_E2.4130.97
427_Q431_L2.4090.97
29_W75_A2.3990.96
147_A150_Q2.3090.96
665_R669_E2.3070.96
445_I451_I2.3030.96
419_E484_R2.2750.95
584_N671_E2.2630.95
546_Y593_M2.2400.95
5_Q62_S2.2350.95
206_Q210_A2.2140.94
661_A664_C2.2060.94
505_L551_F2.1860.94
598_V608_V2.1400.93
572_V582_L2.1350.93
616_G634_M2.1320.93
224_S239_R2.1300.93
230_Y576_N2.1160.93
379_D607_W2.0940.93
166_L185_L2.0190.91
664_C673_L2.0170.91
544_V551_F2.0170.91
376_K630_D1.9910.90
515_I535_L1.9610.90
117_L314_L1.9450.89
276_Q331_A1.9450.89
473_P510_W1.9220.89
381_A400_G1.8840.88
626_G658_A1.8660.87
7_L62_S1.8610.87
328_V348_Y1.8570.87
390_A433_A1.8520.87
386_T389_E1.8130.86
423_F488_R1.7950.85
22_L46_A1.7900.85
505_L554_E1.7800.85
313_G489_A1.7760.84
539_V551_F1.7640.84
625_L646_L1.7570.84
5_Q64_S1.7370.83
377_R399_E1.7320.83
413_R421_E1.7200.82
607_W631_E1.7180.82
278_L310_V1.6960.82
230_Y233_E1.6910.81
400_G437_P1.6890.81
163_A189_Q1.6890.81
389_E544_V1.6870.81
440_F486_I1.6780.81
447_G463_F1.6780.81
69_G72_E1.6580.80
484_R525_D1.6480.80
601_A608_V1.6460.80
390_A438_I1.6310.79
435_D494_N1.6300.79
486_I495_A1.6230.79
480_R514_E1.6230.79
14_L22_L1.6130.78
268_V639_I1.5910.77
450_S575_N1.5890.77
26_C33_I1.5850.77
656_E660_Q1.5820.77
506_D666_S1.5800.77
404_F429_V1.5790.77
420_Q424_E1.5710.76
80_E84_Q1.5700.76
598_V602_H1.5680.76
382_A393_A1.5640.76
445_I493_G1.5620.76
288_M636_S1.5610.76
384_I390_A1.5580.76
341_N344_V1.5580.76
65_L83_I1.5540.75
512_K516_Q1.5530.75
664_C669_E1.5500.75
163_A185_L1.5320.74
233_E466_Y1.5270.74
304_R401_V1.5160.74
181_L647_R1.5130.73
152_S202_T1.5110.73
394_F436_K1.5040.73
652_E655_R1.5030.73
333_C338_I1.5030.73
423_F427_Q1.5010.73
546_Y569_L1.4840.72
167_N171_R1.4700.71
30_Q70_S1.4620.71
537_I623_L1.4590.71
420_Q488_R1.4500.70
549_D603_Q1.4470.70
342_D346_G1.4460.70
128_V345_S1.4370.69
6_F88_I1.4350.69
499_I511_V1.4230.69
240_D275_S1.4220.69
309_P417_P1.4200.68
472_Y479_F1.4190.68
145_I207_G1.4170.68
234_R237_D1.4090.68
623_L674_L1.4040.68
396_N640_P1.4000.67
545_C610_I1.3990.67
595_Q659_R1.3840.66
440_F495_A1.3800.66
314_L318_A1.3730.66
217_E221_A1.3730.66
401_V489_A1.3680.65
545_C606_K1.3650.65
132_T261_L1.3640.65
545_C569_L1.3610.65
274_P399_E1.3580.65
573_D597_I1.3570.65
69_G75_A1.3480.64
286_A472_Y1.3460.64
474_E578_R1.3410.64
32_E45_D1.3390.64
296_T590_F1.3380.64
72_E89_D1.3340.63
121_V331_A1.3290.63
326_P345_S1.3270.63
627_L661_A1.3250.63
331_A481_T1.3240.63
555_V576_N1.3210.63
497_L614_L1.3180.63
387_A425_A1.3110.62
499_I515_I1.3100.62
277_F306_S1.3100.62
155_L197_I1.3090.62
539_V555_V1.3030.62
576_N635_S1.3010.61
596_Q600_T1.3000.61
152_S198_R1.3000.61
230_Y582_L1.2920.61
387_A429_V1.2860.61
277_F299_T1.2760.60
304_R613_E1.2680.59
555_V606_K1.2660.59
507_Q560_I1.2540.59
657_L673_L1.2480.58
429_V666_S1.2470.58
26_C47_K1.2440.58
23_K120_N1.2440.58
345_S349_Q1.2410.58
130_T263_K1.2290.57
159_L163_A1.2210.56
626_G661_A1.2200.56
291_E315_P1.2190.56
598_V630_D1.2170.56
29_W47_K1.2150.56
165_Q244_Q1.2120.56
353_T357_K1.2090.56
499_I535_L1.2060.56
651_S655_R1.2010.55
360_K364_Q1.1960.55
615_G632_L1.1940.55
166_L294_G1.1940.55
242_S463_F1.1910.55
62_S553_D1.1900.54
142_Y266_I1.1860.54
278_L311_L1.1820.54
370_A647_R1.1820.54
430_L494_N1.1810.54
516_Q520_V1.1810.54
241_I380_I1.1800.54
350_V353_T1.1800.54
243_E273_T1.1790.54
356_D360_K1.1790.54
509_L616_G1.1700.53
369_L372_S1.1680.53
629_L632_L1.1530.52
82_Y430_L1.1520.52
209_G250_W1.1460.52
136_S345_S1.1430.51
82_Y86_R1.1390.51
261_L264_P1.1380.51
289_I613_E1.1370.51
81_E85_V1.1360.51
549_D600_T1.1340.51
300_L310_V1.1320.51
416_A453_Y1.1310.51
261_L265_T1.1300.51
427_Q502_V1.1280.50
270_E292_K1.1200.50
439_I631_E1.1200.50
592_R600_T1.1170.50
439_I445_I1.1140.50
579_V582_L1.1130.50
487_L622_P1.1050.49
535_L653_A1.0980.49
291_E312_S1.0960.48
616_G638_R1.0940.48
498_M558_F1.0840.48
131_L321_R1.0820.48
49_S56_G1.0800.47
376_K655_R1.0790.47
161_T248_I1.0750.47
378_I625_L1.0740.47
281_D285_L1.0730.47
186_S576_N1.0690.47
539_V601_A1.0680.47
419_E423_F1.0670.47
194_A197_I1.0640.46
141_S213_I1.0620.46
327_A336_L1.0580.46
322_Y325_Q1.0530.46
349_Q359_Q1.0500.45
505_L615_G1.0460.45
365_A368_Q1.0440.45
51_A223_L1.0430.45
379_D609_G1.0400.45
516_Q519_I1.0390.45
289_I336_L1.0390.45
197_I323_A1.0380.45
210_A613_E1.0340.44
471_I546_Y1.0310.44
420_Q423_F1.0270.44
64_S271_D1.0250.44
299_T337_A1.0240.44
236_S541_V1.0220.44
555_V599_T1.0210.44
508_I543_S1.0210.44
94_Q543_S1.0160.43
33_I46_A1.0130.43
560_I608_V1.0120.43
508_I539_V1.0100.43
546_Y603_Q1.0100.43
419_E489_A1.0070.43
356_D359_Q1.0020.42
145_I148_S1.0010.42
184_H390_A1.0000.42
505_L555_V1.0000.42
230_Y579_V0.9970.42
406_T422_Q0.9970.42
479_F511_V0.9960.42
560_I598_V0.9900.42
445_I455_N0.9880.42
314_L418_D0.9860.41
660_Q664_C0.9850.41
290_L547_I0.9830.41
95_P99_E0.9830.41
10_L89_D0.9820.41
29_W79_L0.9810.41
445_I620_Y0.9800.41
183_A272_L0.9800.41
60_N69_G0.9790.41
548_I600_T0.9780.41
104_P333_C0.9780.41
622_P649_L0.9760.41
305_A636_S0.9750.41
51_A266_I0.9740.41
634_M642_V0.9740.41
363_A366_A0.9710.40
162_L245_L0.9670.40
15_H18_P0.9650.40
22_L35_F0.9650.40
169_Q278_L0.9580.40
463_F490_A0.9570.40
143_R206_Q0.9560.40
230_Y613_E0.9560.40
364_Q539_V0.9560.40
223_L600_T0.9530.39
216_M242_S0.9530.39
127_G156_E0.9530.39
165_Q642_V0.9530.39
10_L88_I0.9510.39
596_Q599_T0.9500.39
489_A634_M0.9500.39
10_L52_L0.9470.39
192_E195_G0.9470.39
157_H203_E0.9450.39
516_Q535_L0.9440.39
238_I545_C0.9430.39
10_L450_S0.9410.39
428_Q656_E0.9410.39
131_L323_A0.9360.38
372_S376_K0.9350.38
379_D598_V0.9340.38
46_A79_L0.9340.38
151_D207_G0.9330.38
331_A489_A0.9330.38
268_V327_A0.9330.38
363_A640_P0.9320.38
372_S624_L0.9320.38
266_I327_A0.9320.38
69_G413_R0.9290.38
212_I245_L0.9290.38
238_I315_P0.9280.38
181_L541_V0.9270.38
312_S362_Q0.9260.38
331_A558_F0.9250.38
336_L506_D0.9250.38
588_P626_G0.9240.38
431_L492_F0.9220.37
266_I533_I0.9210.37
201_M537_I0.9210.37
242_S489_A0.9170.37
413_R580_S0.9170.37
168_Q257_N0.9160.37
660_Q673_L0.9150.37
305_A442_T0.9150.37
25_Q28_Q0.9130.37
394_F404_F0.9100.37
570_Y587_T0.9090.37
18_P417_P0.9090.37
61_D69_G0.9090.37
37_N61_D0.9080.37
23_K241_I0.9070.37
321_R424_E0.9070.37
223_L440_F0.9060.36
127_G476_A0.9050.36
83_I86_R0.9040.36
264_P286_A0.9010.36
242_S313_G0.9010.36
294_G609_G0.8960.36
181_L197_I0.8940.36
75_A535_L0.8940.36
645_Q649_L0.8940.36
133_L323_A0.8930.36
51_A328_V0.8920.36
171_R361_Q0.8890.35
200_L206_Q0.8870.35
341_N381_A0.8870.35
202_T539_V0.8850.35
77_R229_D0.8840.35
252_E477_G0.8820.35
422_Q485_A0.8790.35
425_A543_S0.8790.35
381_A631_E0.8780.35
234_R417_P0.8770.35
479_F593_M0.8770.35
536_G557_F0.8750.35
129_G227_A0.8750.35
115_D267_L0.8710.34
370_A399_E0.8700.34
56_G312_S0.8670.34
416_A479_F0.8660.34
193_F610_I0.8600.34
378_I486_I0.8580.34
119_G580_S0.8570.34
585_P614_L0.8570.34
463_F558_F0.8560.34
50_L223_L0.8560.34
399_E433_A0.8540.33
409_L615_G0.8530.33
413_R453_Y0.8510.33
347_Y351_A0.8500.33
8_C546_Y0.8500.33
285_L479_F0.8480.33
371_Y377_R0.8470.33
526_G608_V0.8460.33
317_D336_L0.8460.33
18_P309_P0.8440.33
290_L294_G0.8440.33
91_D94_Q0.8430.33
423_F492_F0.8430.33
58_L127_G0.8420.33
8_C23_K0.8420.33
349_Q352_Q0.8420.33
404_F438_I0.8410.33
136_S349_Q0.8390.33
67_I72_E0.8370.32
324_G360_K0.8370.32
597_I600_T0.8360.32
27_S186_S0.8360.32
650_D653_A0.8340.32
417_P588_P0.8340.32
196_N228_S0.8340.32
244_Q477_G0.8330.32
277_F281_D0.8300.32
217_E520_V0.8290.32
404_F634_M0.8290.32
410_Y486_I0.8290.32
364_Q380_I0.8280.32
546_Y596_Q0.8220.32
302_L408_M0.8210.32
9_P23_K0.8190.31
78_V81_E0.8190.31
230_Y572_V0.8190.31
45_D362_Q0.8180.31
53_I87_F0.8140.31
13_G16_A0.8120.31
305_A389_E0.8080.31
200_L215_N0.8080.31
162_L244_Q0.8070.31
241_I277_F0.8060.31
312_S510_W0.8060.31
395_A640_P0.8050.31
183_A299_T0.8040.31
155_L159_L0.8040.31
134_L323_A0.8030.31
277_F285_L0.8030.31
35_F83_I0.8020.31
169_Q313_G0.8010.30
195_G202_T0.8000.30
374_D588_P0.7990.30
537_I551_F0.7980.30
263_K284_N0.7980.30
658_A661_A0.7970.30
29_W33_I0.7970.30
541_V623_L0.7960.30
497_L533_I0.7930.30
653_A656_E0.7910.30
86_R89_D0.7890.30
385_G575_N0.7890.30
610_I632_L0.7880.30
126_V560_I0.7870.30
642_V646_L0.7860.30
468_A590_F0.7820.29
305_A533_I0.7810.29
267_L363_A0.7810.29
392_G396_N0.7800.29
442_T486_I0.7800.29
422_Q451_I0.7800.29
314_L471_I0.7780.29
234_R571_A0.7770.29
591_L626_G0.7760.29
63_C67_I0.7760.29
381_A607_W0.7750.29
158_S249_T0.7740.29
163_A497_L0.7740.29
406_T616_G0.7740.29
128_V328_V0.7730.29
162_L248_I0.7730.29
300_L443_M0.7710.29
562_S616_G0.7710.29
410_Y425_A0.7710.29
10_L277_F0.7700.29
49_S295_R0.7700.29
192_E224_S0.7700.29
244_Q290_L0.7680.29
212_I242_S0.7680.29
545_C629_L0.7670.29
234_R374_D0.7660.29
121_V614_L0.7630.28
333_C532_T0.7630.28
544_V597_I0.7630.28
551_F606_K0.7630.28
89_D318_A0.7620.28
208_L305_A0.7610.28
379_D439_I0.7610.28
300_L552_C0.7560.28
306_S331_A0.7550.28
56_G315_P0.7540.28
36_I66_N0.7540.28
569_L617_E0.7530.28
466_Y579_V0.7530.28
389_E392_G0.7530.28
221_A623_L0.7530.28
295_R312_S0.7530.28
421_E580_S0.7520.28
660_Q663_E0.7520.28
240_D624_L0.7500.28
119_G194_A0.7490.28
304_R635_S0.7490.28
241_I271_D0.7460.28
70_S361_Q0.7460.28
190_D556_D0.7460.28
149_A650_D0.7450.27
378_I630_D0.7440.27
547_I550_H0.7440.27
621_L642_V0.7430.27
44_A192_E0.7410.27
37_N230_Y0.7400.27
361_Q364_Q0.7400.27
452_P560_I0.7390.27
447_G576_N0.7380.27
56_G291_E0.7370.27
85_V221_A0.7360.27
289_I314_L0.7360.27
50_L53_I0.7350.27
153_T342_D0.7330.27
408_M411_M0.7330.27
426_Y501_M0.7310.27
171_R174_D0.7310.27
52_L672_A0.7310.27
288_M303_A0.7300.27
95_P229_D0.7290.27
657_L660_Q0.7280.27
225_A228_S0.7280.27
586_I620_Y0.7280.27
138_S359_Q0.7280.27
181_L245_L0.7270.27
213_I380_I0.7270.27
122_L125_G0.7270.27
469_V634_M0.7260.27
78_V296_T0.7250.26
133_L136_S0.7240.26
510_W562_S0.7240.26
41_N635_S0.7230.26
266_I391_P0.7230.26
44_A440_F0.7210.26
462_P567_Q0.7210.26
65_L69_G0.7200.26
305_A308_I0.7200.26
325_Q653_A0.7190.26
201_M351_A0.7180.26
117_L126_V0.7180.26
613_E616_G0.7170.26
13_G17_R0.7170.26
376_K380_I0.7170.26
151_D154_R0.7170.26
23_K510_W0.7160.26
198_R202_T0.7160.26
288_M299_T0.7160.26
476_A479_F0.7160.26
51_A562_S0.7150.26
481_T484_R0.7150.26
537_I558_F0.7150.26
443_M473_P0.7140.26
240_D399_E0.7140.26
41_N135_Q0.7140.26
71_D74_Q0.7130.26
151_D162_L0.7120.26
304_R310_V0.7090.26
343_A502_V0.7080.26
79_L663_E0.7070.26
129_G264_P0.7060.26
168_Q172_E0.7050.25
327_A373_R0.7050.25
470_R536_G0.7040.25
541_V647_R0.7030.25
594_L624_L0.7010.25
425_A428_Q0.7010.25
632_L647_R0.7000.25
313_G386_T0.7000.25
178_K241_I0.6990.25
90_S94_Q0.6990.25
437_P673_L0.6990.25
10_L511_V0.6980.25
588_P591_L0.6980.25
75_A78_V0.6970.25
408_M548_I0.6970.25
360_K478_L0.6960.25
179_T214_S0.6940.25
267_L438_I0.6940.25
197_I535_L0.6930.25
512_K556_D0.6900.25
276_Q297_S0.6890.25
167_N263_K0.6890.25
151_D158_S0.6890.25
634_M639_I0.6870.25
321_R394_F0.6870.25
18_P568_Y0.6860.25
439_I534_T0.6860.25
26_C29_W0.6850.25
276_Q290_L0.6850.25
11_P566_T0.6850.25
308_I479_F0.6840.24
522_L527_L0.6840.24
123_A427_Q0.6830.24
30_Q521_E0.6820.24
79_L486_I0.6820.24
15_H19_A0.6820.24
293_T565_M0.6810.24
501_M568_Y0.6810.24
213_I217_E0.6800.24
475_F589_S0.6800.24
242_S473_P0.6800.24
331_A613_E0.6800.24
534_T607_W0.6800.24
94_Q201_M0.6790.24
241_I463_F0.6780.24
87_F230_Y0.6780.24
111_R114_P0.6780.24
221_A224_S0.6780.24
53_I231_L0.6780.24
79_L360_K0.6770.24
498_M637_P0.6760.24
58_L61_D0.6760.24
327_A654_C0.6750.24
51_A440_F0.6750.24
23_K440_F0.6740.24
548_I558_F0.6730.24
219_V539_V0.6720.24
281_D607_W0.6720.24
469_V502_V0.6710.24
422_Q426_Y0.6710.24
665_R668_Q0.6700.24
634_M638_R0.6700.24
118_Y663_E0.6700.24
74_Q81_E0.6680.24
448_D501_M0.6670.24
152_S162_L0.6660.24
262_E265_T0.6650.24
153_T368_Q0.6630.23
269_A580_S0.6630.23
228_S639_I0.6620.23
479_F545_C0.6610.23
558_F609_G0.6610.23
537_I661_A0.6600.23
160_A164_E0.6600.23
26_C30_Q0.6590.23
194_A354_L0.6590.23
621_L646_L0.6590.23
153_T157_H0.6580.23
505_L509_L0.6580.23
8_C433_A0.6570.23
153_T156_E0.6560.23
47_K435_D0.6550.23
483_L531_E0.6540.23
159_L162_L0.6520.23
230_Y238_I0.6520.23
282_L292_K0.6510.23
516_Q525_D0.6510.23
136_S353_T0.6500.23
189_Q339_N0.6490.23
539_V545_C0.6490.23
667_A675_T0.6490.23
164_E502_V0.6470.23
155_L627_L0.6470.23
265_T642_V0.6460.23
111_R640_P0.6460.23
197_I363_A0.6450.23
114_P640_P0.6440.23
484_R589_S0.6420.23
41_N666_S0.6410.22
63_C69_G0.6390.22
336_L603_Q0.6390.22
266_I653_A0.6390.22
86_R576_N0.6380.22
236_S273_T0.6380.22
180_I295_R0.6380.22
34_T499_I0.6360.22
27_S189_Q0.6360.22
180_I483_L0.6350.22
153_T343_A0.6350.22
295_R315_P0.6350.22
330_D364_Q0.6340.22
406_T509_L0.6340.22
18_P588_P0.6320.22
207_G210_A0.6310.22
199_R202_T0.6300.22
413_R417_P0.6290.22
60_N72_E0.6290.22
103_H160_A0.6290.22
498_M507_Q0.6290.22
457_P669_E0.6290.22
10_L22_L0.6280.22
443_M590_F0.6260.22
278_L473_P0.6260.22
404_F451_I0.6250.22
266_I529_H0.6240.22
166_L319_I0.6240.22
7_L330_D0.6230.22
585_P666_S0.6230.22
197_I264_P0.6220.22
281_D324_G0.6220.22
50_L299_T0.6220.22
224_S343_A0.6210.22
508_I590_F0.6210.22
585_P634_M0.6200.22
479_F514_E0.6190.21
21_E248_I0.6190.21
182_S185_L0.6190.21
41_N185_L0.6180.21
267_L290_L0.6180.21
23_K271_D0.6170.21
413_R416_A0.6170.21
415_S428_Q0.6160.21
504_S582_L0.6160.21
107_R111_R0.6150.21
71_D660_Q0.6130.21
539_V562_S0.6130.21
35_F146_P0.6130.21
218_Q294_G0.6120.21
122_L300_L0.6110.21
511_V514_E0.6110.21
88_I91_D0.6100.21
168_Q517_K0.6090.21
490_A657_L0.6090.21
503_H532_T0.6080.21
419_E551_F0.6080.21
228_S302_L0.6080.21
45_D51_A0.6070.21
629_L658_A0.6070.21
296_T382_A0.6070.21
126_V353_T0.6060.21
366_A515_I0.6050.21
327_A353_T0.6050.21
195_G623_L0.6040.21
234_R568_Y0.6040.21
32_E144_A0.6020.21
74_Q195_G0.6020.21
194_A314_L0.6020.21
379_D576_N0.6020.21
543_S576_N0.6020.21
499_I533_I0.6020.21
390_A393_A0.6010.21
439_I496_Q0.6000.21
20_W366_A0.6000.21
548_I597_I0.5990.21
237_D417_P0.5990.21
440_F550_H0.5990.21
173_R585_P0.5980.21
203_E327_A0.5970.21
618_S642_V0.5960.21
237_D309_P0.5960.21
173_R215_N0.5960.21
429_V438_I0.5950.20
125_G637_P0.5950.20
54_G515_I0.5950.20
61_D299_T0.5940.20
276_Q304_R0.5930.20
300_L408_M0.5930.20
166_L189_Q0.5910.20
576_N582_L0.5900.20
161_T165_Q0.5900.20
136_S669_E0.5900.20
160_A378_I0.5890.20
423_F430_L0.5890.20
126_V233_E0.5890.20
198_R201_M0.5890.20
145_I201_M0.5890.20
18_P237_D0.5890.20
572_V579_V0.5880.20
164_E169_Q0.5870.20
380_I643_K0.5870.20
438_I582_L0.5870.20
35_F497_L0.5870.20
49_S52_L0.5860.20
246_L328_V0.5860.20
131_L512_K0.5860.20
346_G349_Q0.5850.20
102_A263_K0.5840.20
132_T139_L0.5840.20
339_N425_A0.5830.20
32_E52_L0.5830.20
207_G570_Y0.5820.20
231_L643_K0.5820.20
117_L289_I0.5810.20
508_I537_I0.5800.20
385_G437_P0.5800.20
586_I670_I0.5790.20
603_Q625_L0.5790.20
214_S323_A0.5780.20
288_M430_L0.5770.20
374_D417_P0.5760.20
456_I478_L0.5760.20
223_L454_L0.5750.20
378_I439_I0.5740.20
335_V589_S0.5740.20
25_Q29_W0.5730.20
546_Y579_V0.5730.20
192_E273_T0.5720.20
453_Y624_L0.5710.19
196_N551_F0.5700.19
52_L291_E0.5700.19
84_Q89_D0.5700.19
135_Q323_A0.5690.19
188_I245_L0.5680.19
10_L621_L0.5680.19
24_E27_S0.5670.19
67_I76_R0.5670.19
662_C666_S0.5670.19
639_I667_A0.5660.19
68_S642_V0.5660.19
417_P568_Y0.5660.19
33_I326_P0.5660.19
271_D555_V0.5660.19
201_M490_A0.5650.19
423_F445_I0.5650.19
391_P395_A0.5650.19
117_L134_L0.5650.19
273_T469_V0.5650.19
149_A368_Q0.5650.19
301_I304_R0.5640.19
572_V613_E0.5630.19
491_S616_G0.5620.19
44_A206_Q0.5610.19
99_E360_K0.5610.19
537_I585_P0.5610.19
470_R482_Q0.5600.19
357_K360_K0.5600.19
31_S505_L0.5600.19
608_V634_M0.5600.19
246_L539_V0.5590.19
482_Q536_G0.5580.19
268_V289_I0.5580.19
649_L654_C0.5570.19
576_N636_S0.5570.19
342_D651_S0.5570.19
211_A497_L0.5560.19
44_A269_A0.5550.19
155_L484_R0.5550.19
484_R488_R0.5550.19
29_W71_D0.5550.19
201_M208_L0.5540.19
33_I47_K0.5540.19
107_R148_S0.5540.19
370_A646_L0.5530.19
511_V515_I0.5530.19
41_N350_V0.5530.19
215_N388_L0.5520.19
513_G604_R0.5520.19
360_K435_D0.5520.19
123_A439_I0.5520.19
10_L184_H0.5520.19
530_A663_E0.5510.19
100_L668_Q0.5510.19
302_L623_L0.5500.19
340_P417_P0.5500.19
120_N311_L0.5480.19
128_V594_L0.5480.19
130_T264_P0.5480.19
181_L188_I0.5470.19
240_D274_P0.5470.19
22_L503_H0.5460.18
60_N88_I0.5460.18
411_M420_Q0.5460.18
267_L666_S0.5450.18
375_N417_P0.5450.18
223_L495_A0.5450.18
515_I575_N0.5450.18
541_V568_Y0.5450.18
181_L616_G0.5440.18
380_I621_L0.5440.18
387_A663_E0.5440.18
14_L502_V0.5440.18
429_V634_M0.5430.18
309_P568_Y0.5410.18
63_C71_D0.5410.18
45_D646_L0.5400.18
244_Q618_S0.5400.18
144_A656_E0.5400.18
304_R463_F0.5400.18
180_I331_A0.5390.18
215_N264_P0.5390.18
331_A334_G0.5390.18
450_S579_V0.5390.18
10_L181_L0.5380.18
479_F488_R0.5370.18
490_A530_A0.5370.18
361_Q420_Q0.5370.18
344_V348_Y0.5370.18
26_C486_I0.5370.18
586_I661_A0.5370.18
323_A327_A0.5360.18
279_S623_L0.5350.18
32_E129_G0.5350.18
549_D601_A0.5350.18
53_I613_E0.5340.18
161_T225_A0.5340.18
49_S304_R0.5330.18
126_V143_R0.5330.18
353_T478_L0.5330.18
394_F433_A0.5330.18
203_E451_I0.5320.18
70_S257_N0.5320.18
372_S625_L0.5320.18
364_Q648_Q0.5320.18
232_R238_I0.5310.18
67_I75_A0.5310.18
399_E502_V0.5300.18
155_L671_E0.5300.18
112_L669_E0.5300.18
73_E100_L0.5300.18
150_Q346_G0.5300.18
169_Q244_Q0.5300.18
6_F11_P0.5300.18
457_P578_R0.5300.18
14_L445_I0.5290.18
272_L302_L0.5280.18
470_R557_F0.5270.18
120_N476_A0.5270.18
241_I634_M0.5270.18
299_T572_V0.5260.18
200_L652_E0.5260.18
636_S674_L0.5250.18
478_L592_R0.5250.18
167_N483_L0.5250.18
389_E640_P0.5240.18
150_Q655_R0.5240.18
234_R245_L0.5240.18
290_L490_A0.5240.18
439_I491_S0.5230.18
190_D245_L0.5230.18
184_H384_I0.5230.18
180_I278_L0.5220.18
263_K549_D0.5210.18
624_L627_L0.5210.18
502_V519_I0.5210.18
374_D627_L0.5200.17
400_G422_Q0.5200.17
137_D160_A0.5200.17
478_L515_I0.5200.17
28_Q229_D0.5190.17
8_C230_Y0.5190.17
427_Q491_S0.5190.17
149_A167_N0.5180.17
95_P98_A0.5180.17
285_L535_L0.5170.17
264_P299_T0.5170.17
37_N53_I0.5170.17
29_W78_V0.5170.17
268_V291_E0.5170.17
366_A429_V0.5160.17
373_R378_I0.5150.17
49_S276_Q0.5150.17
230_Y635_S0.5150.17
196_N200_L0.5140.17
28_Q31_S0.5130.17
599_T656_E0.5120.17
579_V642_V0.5120.17
618_S668_Q0.5120.17
7_L200_L0.5110.17
551_F668_Q0.5110.17
44_A223_L0.5110.17
657_L664_C0.5110.17
64_S197_I0.5110.17
350_V357_K0.5100.17
11_P339_N0.5100.17
311_L659_R0.5100.17
449_K568_Y0.5100.17
410_Y418_D0.5090.17
337_A344_V0.5090.17
12_N192_E0.5090.17
450_S616_G0.5090.17
267_L593_M0.5090.17
132_T288_M0.5080.17
140_D514_E0.5080.17
234_R588_P0.5080.17
505_L667_A0.5070.17
342_D345_S0.5070.17
562_S594_L0.5070.17
82_Y89_D0.5060.17
160_A258_K0.5060.17
389_E617_E0.5060.17
223_L572_V0.5060.17
161_T342_D0.5060.17
240_D244_Q0.5060.17
182_S669_E0.5060.17
495_A533_I0.5060.17
71_D75_A0.5050.17
288_M337_A0.5050.17
266_I505_L0.5050.17
313_G630_D0.5050.17
35_F391_P0.5050.17
358_R362_Q0.5050.17
609_G630_D0.5040.17
221_A307_A0.5030.17
237_D501_M0.5020.17
223_L493_G0.5020.17
53_I572_V0.5020.17
184_H631_E0.5010.17
392_G653_A0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2wqdA 2 0.6787 100 0.52 Contact Map
2hwgA 2 0.6787 100 0.522 Contact Map
1vbgA 2 0.7545 100 0.572 Contact Map
1kblA 2 0.7569 100 0.573 Contact Map
2x0sA 2 0.7557 100 0.58 Contact Map
2olsA 2 0.6402 100 0.641 Contact Map
2xz9A 2 0.3815 100 0.725 Contact Map
1zymA 2 0.29 100 0.826 Contact Map
4l9zA 5 0.355 100 0.866 Contact Map
3qqwA 3 0.3478 100 0.867 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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