HYFF - ECOLI - GREMLIN Contacts

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HYFF - Hydrogenase-4 component F

UniProt:	P77437	Sequences: MSYSVMFALLLLTPLLFSLLCFACRKRRLSATRTVTVLHSLGITLLLILALWVVQTAADAGEIFAAGLWLHIDGLGGLFLAILGVIGFLTGIYSIGYMRHEVAHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRSSLEAAWKYIIICTVGVAFGLFGTVLVYANAASVMPQAEMAIFWSEVLKQSSLLDPTLMLLAFVFLLIGFGTKTGLFPMHAWLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIIICQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVENMGLVAVELGIGGPLGIFAALLHILNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGALALAGMPPFNIFLSEFMTITAGLARNHLLIIVLLLLLLTLVLAGLVRMAARVLMAKPPQAVNRGDLGWLTTSPMVILLVMMLAMGTHIPQPVIRILAGASTIVLSGTHDLPAQRSTWHDFLPSGTASVSEKHSER	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14214
Length:	526 (457)
Sequences:	19943 (12333)
Seq/√Len:	576.9

ECOLI - HYFF HYFB NUOL HYCC NUOM HYFD NUON
BACSU - MRPA MRPD NDHF
HALSA - Q9HRL3 Q9HRL2 Q9HRT0 Q9HRS9 Q9HRL1 Q9HRS8
SULSO - Q980G8 Q97ZA6 Q97ZA9 Q980G9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
73_D	271_R	4.822	1.00
353_L	390_G	4.666	1.00
128_L	141_A	4.436	1.00
194_M	198_E	3.673	1.00
80_L	131_T	3.664	1.00
154_G	165_A	3.656	1.00
346_N	401_N	3.254	1.00
309_D	368_R	3.217	1.00
167_K	244_D	3.185	1.00
87_G	123_L	3.058	1.00
297_V	428_L	2.932	1.00
343_H	405_S	2.906	1.00
192_S	198_E	2.873	1.00
194_M	197_A	2.774	1.00
308_R	371_N	2.747	1.00
17_F	39_H	2.688	1.00
314_L	358_S	2.678	1.00
388_G	440_A	2.651	1.00
367_T	372_V	2.644	1.00
83_L	130_V	2.638	1.00
15_L	124_F	2.617	1.00
293_G	330_G	2.605	1.00
80_L	127_L	2.507	1.00
125_T	144_A	2.504	1.00
182_G	224_F	2.467	1.00
235_L	326_A	2.423	1.00
369_D	372_V	2.389	1.00
391_A	436_L	2.356	1.00
94_S	115_Y	2.351	1.00
41_L	88_F	2.315	1.00
327_V	425_L	2.243	1.00
313_L	370_L	2.242	1.00
71_H	133_N	2.188	1.00
305_L	434_A	2.187	1.00
84_G	127_L	2.169	1.00
262_L	318_S	2.130	1.00
287_R	291_I	1.951	1.00
328_E	409_T	1.946	1.00
380_M	383_T	1.937	1.00
317_S	435_G	1.920	1.00
342_L	405_S	1.910	1.00
298_A	428_L	1.884	1.00
308_R	369_D	1.875	1.00
438_R	442_R	1.875	1.00
230_G	235_L	1.845	1.00
301_A	320_E	1.842	1.00
73_D	76_G	1.806	1.00
44_T	85_V	1.787	1.00
459_W	463_S	1.787	1.00
290_L	330_G	1.764	1.00
164_A	248_E	1.752	1.00
82_I	348_S	1.744	1.00
226_L	230_G	1.716	1.00
135_L	272_Y	1.715	1.00
310_I	439_M	1.713	1.00
138_M	268_V	1.708	1.00
294_M	424_L	1.700	1.00
234_G	242_L	1.685	1.00
410_I	425_L	1.669	1.00
135_L	199_M	1.662	1.00
349_L	471_M	1.660	1.00
185_L	221_A	1.656	1.00
383_T	456_D	1.652	1.00
270_I	329_L	1.647	1.00
284_F	287_R	1.646	1.00
22_F	25_R	1.646	1.00
307_Q	312_R	1.644	1.00
331_I	336_G	1.640	1.00
28_R	31_A	1.635	1.00
339_A	412_A	1.633	1.00
377_L	384_A	1.621	1.00
76_G	267_L	1.587	1.00
198_E	201_I	1.577	1.00
189_N	221_A	1.563	1.00
236_F	295_L	1.547	1.00
78_L	345_L	1.542	1.00
118_F	151_F	1.533	1.00
470_V	474_A	1.521	1.00
132_S	137_V	1.520	1.00
30_S	33_R	1.515	1.00
43_I	47_L	1.511	1.00
129_V	264_C	1.504	1.00
389_G	469_L	1.473	1.00
216_T	220_L	1.469	1.00
71_H	74_G	1.460	1.00
41_L	45_L	1.458	1.00
301_A	428_L	1.455	1.00
387_F	391_A	1.452	1.00
235_L	292_F	1.447	1.00
187_Y	193_V	1.444	1.00
134_N	194_M	1.442	1.00
329_L	340_A	1.423	1.00
133_N	197_A	1.417	1.00
182_G	228_G	1.416	1.00
45_L	49_L	1.415	1.00
30_S	34_T	1.413	1.00
47_L	84_G	1.402	1.00
29_L	33_R	1.400	1.00
289_L	330_G	1.400	1.00
11_L	124_F	1.400	1.00
49_L	53_V	1.398	1.00
91_G	116_Y	1.396	1.00
269_L	326_A	1.393	1.00
152_L	253_V	1.391	1.00
11_L	14_P	1.386	1.00
31_A	34_T	1.382	1.00
458_G	461_T	1.381	1.00
229_F	268_V	1.380	1.00
411_T	415_A	1.377	1.00
325_V	340_A	1.376	1.00
387_F	439_M	1.375	1.00
226_L	289_L	1.372	1.00
40_S	43_I	1.370	1.00
91_G	119_F	1.368	1.00
466_V	470_V	1.354	1.00
328_E	336_G	1.342	1.00
184_V	188_A	1.337	1.00
270_I	340_A	1.334	1.00
286_N	290_L	1.330	1.00
134_N	193_V	1.327	1.00
182_G	221_A	1.327	1.00
354_L	390_G	1.326	1.00
481_Q	485_R	1.314	1.00
384_A	445_M	1.313	1.00
182_G	225_L	1.308	1.00
350_A	393_A	1.308	1.00
39_H	43_I	1.300	1.00
38_L	42_G	1.296	1.00
159_R	248_E	1.295	1.00
160_S	248_E	1.294	1.00
384_A	440_A	1.267	1.00
72_I	131_T	1.266	1.00
93_Y	356_C	1.263	1.00
467_I	471_M	1.261	1.00
328_E	340_A	1.252	1.00
69_W	133_N	1.250	1.00
331_I	413_G	1.243	1.00
327_V	413_G	1.242	1.00
40_S	44_T	1.237	1.00
464_P	467_I	1.234	1.00
244_D	312_R	1.234	1.00
86_I	348_S	1.233	1.00
78_L	341_L	1.231	1.00
139_W	180_L	1.224	1.00
370_L	443_V	1.222	1.00
171_I	240_A	1.211	1.00
413_G	422_I	1.208	1.00
86_I	352_T	1.207	1.00
459_W	462_T	1.206	1.00
179_G	228_G	1.206	1.00
346_N	405_S	1.200	1.00
293_G	323_G	1.195	1.00
33_R	37_V	1.189	1.00
18_S	22_F	1.184	1.00
49_L	52_W	1.183	1.00
290_L	421_I	1.178	1.00
299_V	303_F	1.177	1.00
79_F	344_I	1.175	1.00
48_I	52_W	1.173	1.00
96_G	99_R	1.170	1.00
138_M	196_Q	1.167	1.00
25_R	113_C	1.161	1.00
230_G	292_F	1.159	1.00
460_L	464_P	1.156	1.00
89_L	467_I	1.155	1.00
386_L	469_L	1.153	1.00
40_S	47_L	1.152	1.00
18_S	121_L	1.150	1.00
394_L	436_L	1.143	1.00
61_G	67_G	1.143	1.00
432_V	435_G	1.139	1.00
382_F	466_V	1.138	1.00
482_P	485_R	1.138	1.00
47_L	51_L	1.137	1.00
390_G	469_L	1.135	1.00
414_L	422_I	1.132	1.00
135_L	183_T	1.131	1.00
362_L	368_R	1.128	1.00
185_L	217_L	1.121	1.00
391_A	440_A	1.121	1.00
163_E	167_K	1.119	1.00
291_I	295_L	1.115	1.00
471_M	475_M	1.108	1.00
183_T	225_L	1.098	1.00
357_G	387_F	1.093	1.00
386_L	465_M	1.089	1.00
57_A	61_G	1.084	1.00
320_E	432_V	1.082	1.00
36_T	116_Y	1.080	1.00
189_N	217_L	1.079	1.00
122_F	126_M	1.065	1.00
88_F	92_I	1.065	1.00
347_H	351_K	1.059	1.00
423_V	427_L	1.059	1.00
388_G	444_L	1.058	1.00
84_G	88_F	1.058	1.00
72_I	77_G	1.055	1.00
75_L	270_I	1.050	1.00
408_M	411_T	1.050	1.00
236_F	299_V	1.050	1.00
158_Q	161_S	1.050	1.00
339_A	408_M	1.049	1.00
179_G	183_T	1.048	1.00
382_F	385_V	1.046	1.00
233_T	266_L	1.045	1.00
27_R	30_S	1.043	1.00
59_D	63_I	1.042	1.00
357_G	465_M	1.039	1.00
75_L	341_L	1.038	1.00
293_G	327_V	1.035	1.00
44_T	84_G	1.031	1.00
119_F	256_L	1.029	1.00
175_G	231_T	1.028	1.00
336_G	412_A	1.027	1.00
46_L	50_A	1.024	1.00
136_I	193_V	1.021	1.00
10_L	14_P	1.019	1.00
420_L	423_V	1.016	1.00
392_L	397_M	1.016	1.00
85_V	89_L	1.015	1.00
383_T	457_L	1.015	1.00
364_K	380_M	1.014	1.00
96_G	460_L	1.014	1.00
76_G	271_R	1.012	1.00
387_F	444_L	1.010	1.00
35_V	39_H	1.007	1.00
120_H	124_F	1.006	1.00
258_S	318_S	0.998	1.00
231_T	238_M	0.995	1.00
251_S	311_K	0.995	1.00
374_C	449_P	0.988	1.00
266_L	325_V	0.987	1.00
219_L	285_P	0.984	1.00
57_A	60_A	0.979	1.00
370_L	442_R	0.979	1.00
221_A	225_L	0.978	1.00
8_A	11_L	0.977	1.00
34_T	37_V	0.977	1.00
32_T	36_T	0.976	1.00
44_T	48_I	0.975	1.00
93_Y	359_G	0.966	1.00
219_L	284_F	0.966	1.00
300_A	323_G	0.966	1.00
126_M	260_V	0.965	1.00
301_A	435_G	0.965	1.00
133_N	194_M	0.964	1.00
190_A	199_M	0.963	1.00
12_L	16_L	0.962	1.00
386_L	466_V	0.960	1.00
37_V	40_S	0.960	1.00
186_V	221_A	0.959	1.00
149_S	261_L	0.959	1.00
469_L	473_L	0.958	1.00
83_L	123_L	0.957	1.00
321_N	343_H	0.955	1.00
86_I	259_A	0.955	1.00
360_N	383_T	0.950	1.00
226_L	269_L	0.950	1.00
216_T	219_L	0.948	1.00
283_D	286_N	0.946	1.00
58_A	61_G	0.946	1.00
302_F	431_L	0.945	1.00
215_P	219_L	0.944	1.00
197_A	201_I	0.942	1.00
361_V	376_M	0.939	1.00
178_F	227_I	0.938	1.00
161_S	248_E	0.937	1.00
401_N	475_M	0.937	1.00
318_S	347_H	0.936	1.00
10_L	46_L	0.935	1.00
36_T	40_S	0.934	1.00
310_I	358_S	0.934	1.00
469_L	472_M	0.933	1.00
360_N	457_L	0.933	1.00
125_T	148_S	0.933	1.00
70_L	131_T	0.932	1.00
428_L	431_L	0.932	1.00
255_A	356_C	0.929	1.00
192_S	199_M	0.928	1.00
44_T	47_L	0.928	1.00
382_F	386_L	0.925	1.00
59_D	62_E	0.923	1.00
56_T	59_D	0.922	1.00
36_T	39_H	0.921	1.00
301_A	431_L	0.921	1.00
47_L	50_A	0.919	1.00
364_K	461_T	0.918	1.00
223_V	227_I	0.916	1.00
43_I	46_L	0.914	1.00
365_Y	373_V	0.913	1.00
153_V	245_A	0.911	1.00
40_S	46_L	0.910	1.00
297_V	323_G	0.910	1.00
79_F	267_L	0.908	1.00
214_D	218_M	0.907	1.00
162_L	165_A	0.906	1.00
374_C	442_R	0.906	1.00
321_N	435_G	0.906	1.00
295_L	299_V	0.905	1.00
384_A	444_L	0.905	1.00
353_L	468_L	0.905	1.00
196_Q	200_A	0.905	1.00
338_F	487_L	0.902	1.00
333_G	336_G	0.902	1.00
254_S	262_L	0.901	1.00
121_L	148_S	0.899	1.00
342_L	346_N	0.897	1.00
267_L	271_R	0.896	1.00
18_S	117_G	0.895	1.00
363_L	455_G	0.894	1.00
139_W	143_E	0.893	1.00
42_G	46_L	0.891	1.00
96_G	458_G	0.890	1.00
407_F	411_T	0.889	1.00
269_L	329_L	0.888	1.00
145_T	261_L	0.885	1.00
178_F	224_F	0.885	1.00
187_Y	190_A	0.881	1.00
34_T	38_L	0.880	1.00
33_R	36_T	0.880	1.00
243_P	316_Y	0.880	1.00
290_L	293_G	0.878	1.00
321_N	432_V	0.875	1.00
87_G	119_F	0.875	1.00
215_P	218_M	0.870	1.00
360_N	465_M	0.869	1.00
185_L	189_N	0.863	1.00
266_L	344_I	0.861	1.00
220_L	224_F	0.861	1.00
122_F	149_S	0.861	1.00
328_E	339_A	0.861	1.00
374_C	446_A	0.858	1.00
130_V	267_L	0.854	1.00
310_I	373_V	0.850	1.00
419_L	423_V	0.850	1.00
69_W	194_M	0.849	1.00
14_P	18_S	0.848	1.00
440_A	445_M	0.848	1.00
325_V	344_I	0.845	1.00
89_L	464_P	0.844	1.00
287_R	290_L	0.843	1.00
401_N	472_M	0.842	1.00
76_G	80_L	0.841	1.00
463_S	467_I	0.839	1.00
380_M	456_D	0.837	1.00
313_L	439_M	0.836	1.00
32_T	35_V	0.836	1.00
57_A	69_W	0.835	1.00
385_V	389_G	0.835	1.00
367_T	373_V	0.834	1.00
82_I	345_L	0.834	1.00
309_D	369_D	0.833	1.00
385_V	444_L	0.831	1.00
350_A	402_I	0.830	1.00
266_L	326_A	0.830	1.00
139_W	183_T	0.829	1.00
384_A	388_G	0.825	1.00
126_M	145_T	0.823	1.00
214_D	217_L	0.823	1.00
304_I	435_G	0.823	1.00
192_S	196_Q	0.822	1.00
436_L	439_M	0.819	1.00
26_K	29_L	0.819	1.00
126_M	261_L	0.818	1.00
115_Y	252_P	0.818	1.00
297_V	327_V	0.817	1.00
81_A	85_V	0.817	1.00
95_I	460_L	0.816	1.00
258_S	351_K	0.814	1.00
294_M	327_V	0.812	1.00
31_A	35_V	0.812	1.00
379_I	448_P	0.809	1.00
90_T	356_C	0.808	1.00
290_L	294_M	0.806	1.00
314_L	354_L	0.806	1.00
324_L	409_T	0.803	1.00
40_S	91_G	0.802	1.00
26_K	30_S	0.801	1.00
301_A	317_S	0.801	1.00
343_H	350_A	0.800	1.00
59_D	67_G	0.799	1.00
125_T	141_A	0.799	1.00
55_Q	58_A	0.798	1.00
18_S	21_C	0.797	1.00
13_T	17_F	0.796	1.00
19_L	22_F	0.795	1.00
333_G	412_A	0.795	1.00
127_L	131_T	0.790	1.00
8_A	58_A	0.790	1.00
462_T	466_V	0.790	1.00
457_L	462_T	0.787	1.00
210_S	213_L	0.786	1.00
11_L	70_L	0.786	1.00
142_I	179_G	0.785	1.00
18_S	124_F	0.785	1.00
150_A	165_A	0.783	1.00
300_A	303_F	0.782	1.00
247_S	258_S	0.781	1.00
173_T	176_V	0.778	1.00
153_V	257_L	0.778	1.00
334_P	338_F	0.777	1.00
222_F	285_P	0.777	1.00
160_S	163_E	0.776	1.00
9_L	13_T	0.776	1.00
393_A	400_F	0.775	1.00
290_L	327_V	0.773	1.00
83_L	126_M	0.772	1.00
66_A	136_I	0.772	1.00
160_S	247_S	0.770	1.00
219_L	223_V	0.769	1.00
317_S	347_H	0.768	1.00
449_P	452_V	0.765	1.00
90_T	255_A	0.761	1.00
36_T	43_I	0.761	1.00
77_G	81_A	0.760	1.00
378_K	381_P	0.755	1.00
266_L	322_M	0.754	1.00
50_A	53_V	0.754	1.00
75_L	267_L	0.750	1.00
47_L	80_L	0.749	1.00
145_T	264_C	0.749	1.00
270_I	337_I	0.748	1.00
86_I	256_L	0.748	1.00
298_A	302_F	0.748	1.00
391_A	439_M	0.744	1.00
29_L	32_T	0.737	1.00
399_P	477_T	0.735	1.00
150_A	172_C	0.735	1.00
69_W	134_N	0.734	1.00
300_A	320_E	0.734	1.00
288_L	291_I	0.734	1.00
331_I	416_R	0.733	1.00
324_L	428_L	0.733	1.00
97_Y	252_P	0.732	1.00
153_V	249_A	0.732	1.00
389_G	473_L	0.732	1.00
193_V	198_E	0.731	1.00
456_D	462_T	0.730	1.00
57_A	62_E	0.729	1.00
17_F	120_H	0.728	1.00
113_C	117_G	0.727	1.00
122_F	261_L	0.726	1.00
134_N	137_V	0.726	1.00
28_R	32_T	0.724	1.00
22_F	117_G	0.723	1.00
17_F	21_C	0.722	1.00
293_G	326_A	0.722	1.00
350_A	472_M	0.722	1.00
122_F	256_L	0.711	1.00
396_G	406_E	0.711	1.00
43_I	50_A	0.711	1.00
213_L	216_T	0.709	1.00
14_P	17_F	0.709	1.00
254_S	311_K	0.707	1.00
395_A	433_L	0.707	1.00
437_V	441_A	0.706	1.00
424_L	428_L	0.703	1.00
41_L	52_W	0.701	1.00
282_S	286_N	0.699	1.00
72_I	76_G	0.697	1.00
468_L	472_M	0.695	1.00
272_Y	276_I	0.695	1.00
321_N	351_K	0.694	1.00
186_V	225_L	0.694	1.00
212_L	215_P	0.694	1.00
294_M	298_A	0.693	1.00
220_L	223_V	0.691	1.00
430_T	434_A	0.691	1.00
307_Q	316_Y	0.690	1.00
474_A	482_P	0.690	1.00
303_F	316_Y	0.688	1.00
138_M	179_G	0.688	1.00
142_I	264_C	0.688	1.00
336_G	340_A	0.686	1.00
247_S	309_D	0.686	1.00
43_I	84_G	0.683	1.00
180_L	184_V	0.681	1.00
48_I	81_A	0.680	1.00
356_C	464_P	0.679	1.00
54_V	57_A	0.677	1.00
37_V	41_L	0.673	1.00
463_S	466_V	0.671	1.00
410_I	422_I	0.671	1.00
218_M	221_A	0.671	1.00
310_I	443_V	0.670	1.00
175_G	228_G	0.669	1.00
385_V	388_G	0.669	1.00
75_L	79_F	0.669	1.00
473_L	476_G	0.669	1.00
133_N	137_V	0.668	1.00
186_V	199_M	0.665	1.00
217_L	221_A	0.662	1.00
382_F	462_T	0.662	1.00
27_R	32_T	0.661	1.00
11_L	131_T	0.661	1.00
89_L	352_T	0.659	1.00
166_W	170_I	0.659	1.00
393_A	402_I	0.658	1.00
251_S	359_G	0.657	1.00
259_A	263_N	0.657	1.00
37_V	92_I	0.656	1.00
135_L	186_V	0.655	1.00
37_V	44_T	0.654	1.00
38_L	41_L	0.651	1.00
41_L	44_T	0.651	1.00
16_L	20_L	0.651	1.00
317_S	351_K	0.649	1.00
14_P	124_F	0.643	1.00
454_R	457_L	0.642	1.00
242_L	262_L	0.641	1.00
396_G	402_I	0.641	1.00
475_M	483_V	0.638	1.00
297_V	324_L	0.638	1.00
249_A	254_S	0.637	1.00
94_S	97_Y	0.635	1.00
349_L	401_N	0.634	1.00
317_S	321_N	0.633	1.00
357_G	386_L	0.631	1.00
37_V	43_I	0.630	1.00
81_A	84_G	0.630	1.00
353_L	465_M	0.629	1.00
258_S	347_H	0.629	1.00
240_A	243_P	0.627	1.00
258_S	262_L	0.624	1.00
410_I	429_L	0.624	1.00
341_L	487_L	0.622	1.00
440_A	444_L	0.621	1.00
185_L	220_L	0.621	1.00
400_F	404_L	0.621	1.00
254_S	347_H	0.618	1.00
83_L	127_L	0.618	1.00
8_A	68_L	0.618	1.00
143_E	232_K	0.617	1.00
33_R	43_I	0.617	1.00
9_L	46_L	0.616	1.00
298_A	424_L	0.615	1.00
156_Y	159_R	0.615	1.00
29_L	36_T	0.614	1.00
386_L	390_G	0.612	1.00
226_L	285_P	0.612	1.00
46_L	49_L	0.612	1.00
482_P	486_I	0.610	1.00
93_Y	255_A	0.608	1.00
58_A	62_E	0.608	1.00
377_L	444_L	0.608	1.00
51_L	81_A	0.607	1.00
71_H	197_A	0.606	1.00
90_T	252_P	0.605	1.00
87_G	256_L	0.604	1.00
28_R	33_R	0.603	1.00
293_G	297_V	0.603	1.00
85_V	471_M	0.602	1.00
36_T	91_G	0.602	1.00
242_L	245_A	0.601	1.00
434_A	438_R	0.600	1.00
343_H	346_N	0.600	1.00
47_L	81_A	0.599	1.00
25_R	29_L	0.597	1.00
94_S	252_P	0.597	1.00
363_L	461_T	0.592	1.00
335_L	415_A	0.591	1.00
433_L	437_V	0.591	1.00
301_A	432_V	0.591	1.00
254_S	257_L	0.590	1.00
284_F	288_L	0.589	1.00
251_S	254_S	0.588	1.00
115_Y	253_V	0.588	1.00
236_F	300_A	0.585	1.00
126_M	264_C	0.584	1.00
303_F	306_V	0.584	1.00
269_L	276_I	0.582	1.00
412_A	416_R	0.581	1.00
43_I	53_V	0.581	1.00
345_L	475_M	0.581	1.00
376_M	380_M	0.581	1.00
133_N	271_R	0.580	1.00
183_T	193_V	0.580	1.00
375_G	381_P	0.580	1.00
33_R	95_I	0.580	1.00
10_L	22_F	0.580	1.00
404_L	476_G	0.578	1.00
79_F	83_L	0.574	1.00
90_T	119_F	0.572	1.00
406_E	429_L	0.572	1.00
92_I	464_P	0.572	1.00
123_L	127_L	0.572	1.00
197_A	200_A	0.571	1.00
84_G	123_L	0.571	1.00
350_A	394_L	0.571	1.00
103_A	114_D	0.570	1.00
89_L	468_L	0.570	1.00
375_G	448_P	0.570	1.00
94_S	116_Y	0.569	1.00
139_W	176_V	0.565	0.99
200_A	274_I	0.564	0.99
291_I	294_M	0.564	0.99
259_A	352_T	0.563	0.99
342_L	408_M	0.562	0.99
308_R	317_S	0.561	0.99
243_P	319_V	0.560	0.99
360_N	461_T	0.559	0.99
307_Q	313_L	0.558	0.99
39_H	120_H	0.557	0.99
247_S	312_R	0.557	0.99
36_T	120_H	0.556	0.99
118_F	148_S	0.556	0.99
15_L	19_L	0.556	0.99
82_I	344_I	0.556	0.99
347_H	355_F	0.554	0.99
357_G	390_G	0.554	0.99
115_Y	155_I	0.553	0.99
381_P	384_A	0.553	0.99
8_A	12_L	0.551	0.99
217_L	220_L	0.551	0.99
38_L	45_L	0.551	0.99
377_L	388_G	0.551	0.99
360_N	364_K	0.550	0.99
370_L	373_V	0.550	0.99
37_V	51_L	0.550	0.99
408_M	484_I	0.550	0.99
386_L	462_T	0.549	0.99
132_S	141_A	0.546	0.99
226_L	292_F	0.544	0.99
233_T	269_L	0.543	0.99
338_F	484_I	0.543	0.99
303_F	307_Q	0.542	0.99
135_L	196_Q	0.540	0.99
34_T	40_S	0.540	0.99
481_Q	484_I	0.540	0.99
388_G	445_M	0.538	0.99
191_A	194_M	0.538	0.99
321_N	324_L	0.538	0.99
10_L	13_T	0.537	0.99
14_P	22_F	0.536	0.99
375_G	446_A	0.536	0.99
163_E	244_D	0.535	0.99
190_A	194_M	0.535	0.99
18_S	26_K	0.535	0.99
302_F	306_V	0.534	0.99
224_F	228_G	0.534	0.99
234_G	262_L	0.534	0.99
21_C	25_R	0.533	0.99
262_L	322_M	0.532	0.99
250_P	311_K	0.532	0.99
98_M	101_E	0.530	0.99
43_I	127_L	0.530	0.99
357_G	383_T	0.530	0.99
263_N	322_M	0.530	0.99
38_L	43_I	0.529	0.99
44_T	88_F	0.528	0.99
274_I	277_C	0.528	0.99
41_L	48_I	0.526	0.99
345_L	483_V	0.525	0.99
196_Q	199_M	0.525	0.99
404_L	477_T	0.524	0.99
233_T	265_A	0.523	0.99
395_A	400_F	0.523	0.99
370_L	439_M	0.523	0.99
388_G	391_A	0.523	0.99
61_G	65_A	0.522	0.99
10_L	43_I	0.521	0.99
46_L	52_W	0.520	0.99
310_I	361_V	0.519	0.99
44_T	50_A	0.519	0.99
384_A	443_V	0.517	0.99
25_R	28_R	0.517	0.99
390_G	472_M	0.516	0.99
78_L	487_L	0.516	0.99
222_F	226_L	0.515	0.99
60_A	63_I	0.515	0.99
92_I	463_S	0.515	0.99
42_G	47_L	0.514	0.99
426_L	429_L	0.514	0.99
294_M	421_I	0.513	0.99
235_L	238_M	0.512	0.99
86_I	260_V	0.509	0.99
378_K	447_K	0.508	0.99
115_Y	152_L	0.506	0.99
149_S	152_L	0.506	0.99
51_L	486_I	0.505	0.99
324_L	425_L	0.504	0.99
398_P	403_F	0.504	0.99
333_G	337_I	0.503	0.99
396_G	400_F	0.502	0.99
296_S	326_A	0.500	0.99
318_S	322_M	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3rkoM	1	0.903	100	0.216	Contact Map
4he8L	1	0.9525	100	0.238	Contact Map
3rkoL	1	0.9373	100	0.241	Contact Map
3rkoN	1	0.8707	100	0.251	Contact Map
4he8M	1	0.8669	100	0.259	Contact Map
4he8N	1	0.8099	100	0.312	Contact Map
4he8K	1	0.1749	39.8	0.965	Contact Map
3rkoK	1	0.1825	33.7	0.966	Contact Map
3wu2X	1	0.0703	5.6	0.976	Contact Map
4he8J	1	0.2852	4	0.978	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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