LSRK - ECOLI - GREMLIN Contacts

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LSRK - Autoinducer 2 kinase LsrK

UniProt:	P77432	Sequences: MARLFTLSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWRHLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNEGAPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSDIYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADILSPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAERLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKATLFRALEENAAIVSACNLQQIADFSNIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIPVVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAVYQDQLGLVDHGLTTSLWKAPGL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13804
Length:	530 (474)
Sequences:	12491 (8516)
Seq/√Len:	391.2

ECOLI - LSRK ARAB LYXK XYLB GLPK RHAB FUCK YGCE
BACSU - GNTK XYLB ARAB YOAC GLPK RHAB
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
205_P	215_A	4.117	1.00
119_E	156_H	3.750	1.00
30_D	34_N	3.538	1.00
26_A	69_C	3.311	1.00
122_E	156_H	3.281	1.00
406_A	502_R	2.861	1.00
197_D	200_T	2.860	1.00
406_A	410_Q	2.831	1.00
138_A	204_K	2.797	1.00
446_P	489_T	2.782	1.00
413_A	445_L	2.741	1.00
41_A	68_E	2.710	1.00
437_Q	441_D	2.696	1.00
351_V	392_T	2.695	1.00
106_I	161_I	2.663	1.00
378_F	393_L	2.654	1.00
196_L	221_V	2.639	1.00
41_A	72_Q	2.584	1.00
39_G	72_Q	2.582	1.00
223_E	226_T	2.546	1.00
28_I	73_A	2.544	1.00
422_S	448_N	2.537	1.00
473_S	476_E	2.498	1.00
472_S	476_E	2.468	1.00
433_K	486_R	2.444	1.00
107_W	158_R	2.440	1.00
202_D	215_A	2.418	1.00
63_W	178_M	2.410	1.00
101_N	166_S	2.388	1.00
60_N	178_M	2.384	1.00
100_N	164_Q	2.364	1.00
197_D	204_K	2.350	1.00
406_A	499_Q	2.273	1.00
340_T	343_L	2.257	1.00
208_L	215_A	2.255	1.00
182_E	220_P	2.158	1.00
17_L	66_A	2.141	1.00
205_P	209_D	2.097	1.00
251_G	256_L	2.086	1.00
176_A	250_G	2.086	1.00
27_V	457_A	2.032	1.00
317_T	397_L	2.012	1.00
12_Y	85_A	2.003	1.00
23_S	40_Q	1.975	1.00
122_E	126_L	1.946	1.00
60_N	104_A	1.935	1.00
491_D	494_K	1.935	1.00
232_S	235_A	1.934	1.00
72_Q	76_N	1.919	1.00
134_E	137_R	1.914	1.00
350_R	391_A	1.905	1.00
277_W	314_T	1.901	1.00
180_S	247_V	1.894	1.00
451_V	483_R	1.891	1.00
389_N	392_T	1.890	1.00
413_A	419_H	1.879	1.00
14_L	465_G	1.869	1.00
51_V	54_S	1.865	1.00
44_R	61_K	1.861	1.00
444_G	495_H	1.848	1.00
343_L	346_E	1.842	1.00
357_G	504_K	1.838	1.00
15_M	70_M	1.833	1.00
425_F	436_S	1.819	1.00
502_R	506_Q	1.819	1.00
184_A	222_K	1.795	1.00
15_M	26_A	1.793	1.00
152_L	156_H	1.786	1.00
19_A	24_I	1.778	1.00
167_T	183_L	1.769	1.00
13_Y	36_I	1.765	1.00
248_V	467_G	1.750	1.00
233_S	243_A	1.733	1.00
321_F	397_L	1.730	1.00
138_A	206_A	1.717	1.00
448_N	487_T	1.713	1.00
13_Y	28_I	1.710	1.00
222_K	226_T	1.705	1.00
134_E	138_A	1.705	1.00
134_E	206_A	1.698	1.00
100_N	104_A	1.696	1.00
354_G	357_G	1.691	1.00
354_G	392_T	1.685	1.00
98_L	154_L	1.656	1.00
103_G	177_Y	1.647	1.00
121_S	125_E	1.636	1.00
441_D	494_K	1.633	1.00
227_L	230_V	1.632	1.00
268_Q	422_S	1.631	1.00
339_D	343_L	1.628	1.00
446_P	487_T	1.624	1.00
97_V	171_I	1.609	1.00
118_R	122_E	1.601	1.00
403_I	501_S	1.588	1.00
441_D	491_D	1.578	1.00
347_M	350_R	1.569	1.00
227_L	248_V	1.564	1.00
507_A	511_D	1.559	1.00
319_R	323_D	1.559	1.00
375_A	382_S	1.547	1.00
358_V	378_F	1.545	1.00
124_K	132_E	1.533	1.00
495_H	499_Q	1.524	1.00
199_T	286_P	1.522	1.00
98_L	217_I	1.520	1.00
410_Q	506_Q	1.504	1.00
347_M	391_A	1.495	1.00
12_Y	83_Y	1.493	1.00
266_P	284_A	1.484	1.00
46_L	61_K	1.480	1.00
160_D	163_R	1.455	1.00
348_A	434_L	1.450	1.00
493_E	496_E	1.444	1.00
133_N	137_R	1.437	1.00
14_L	470_I	1.435	1.00
58_D	61_K	1.429	1.00
410_Q	413_A	1.428	1.00
39_G	73_A	1.420	1.00
39_G	69_C	1.416	1.00
433_K	449_I	1.405	1.00
63_W	67_C	1.404	1.00
176_A	228_L	1.400	1.00
37_A	73_A	1.397	1.00
433_K	488_H	1.391	1.00
74_L	81_P	1.382	1.00
451_V	485_E	1.378	1.00
395_R	399_E	1.377	1.00
17_L	70_M	1.372	1.00
242_K	245_T	1.372	1.00
346_E	350_R	1.368	1.00
31_L	470_I	1.357	1.00
153_W	157_H	1.356	1.00
60_N	64_Q	1.356	1.00
86_A	464_A	1.354	1.00
434_L	438_I	1.351	1.00
180_S	229_G	1.349	1.00
344_L	394_F	1.347	1.00
230_V	244_G	1.346	1.00
422_S	446_P	1.330	1.00
465_G	471_F	1.328	1.00
37_A	76_N	1.316	1.00
174_W	178_M	1.308	1.00
99_Y	169_T	1.299	1.00
273_G	439_L	1.298	1.00
402_A	438_I	1.287	1.00
176_A	184_A	1.286	1.00
214_R	217_I	1.270	1.00
311_S	404_V	1.263	1.00
117_A	121_S	1.263	1.00
269_T	420_P	1.262	1.00
347_M	390_K	1.256	1.00
119_E	152_L	1.255	1.00
93_R	252_G	1.249	1.00
24_I	66_A	1.249	1.00
345_E	349_S	1.246	1.00
187_P	201_R	1.244	1.00
222_K	228_L	1.242	1.00
402_A	439_L	1.239	1.00
402_A	442_V	1.238	1.00
80_A	83_Y	1.237	1.00
28_I	79_I	1.232	1.00
126_L	131_F	1.231	1.00
155_A	162_Y	1.230	1.00
449_I	488_H	1.229	1.00
134_E	210_M	1.222	1.00
208_L	218_L	1.221	1.00
271_V	439_L	1.218	1.00
431_K	453_K	1.217	1.00
126_L	210_M	1.203	1.00
148_I	211_A	1.195	1.00
438_I	442_V	1.192	1.00
462_I	481_L	1.191	1.00
358_V	362_F	1.183	1.00
95_G	108_A	1.182	1.00
496_E	500_D	1.179	1.00
227_L	246_P	1.172	1.00
17_L	26_A	1.170	1.00
346_E	349_S	1.165	1.00
407_C	506_Q	1.164	1.00
64_Q	68_E	1.164	1.00
345_E	433_K	1.163	1.00
135_V	143_L	1.162	1.00
410_Q	502_R	1.162	1.00
267_A	421_S	1.161	1.00
24_I	65_L	1.160	1.00
406_A	443_S	1.158	1.00
356_W	385_P	1.158	1.00
158_R	161_I	1.157	1.00
325_F	393_L	1.156	1.00
251_G	463_A	1.155	1.00
206_A	209_D	1.153	1.00
444_G	499_Q	1.152	1.00
66_A	175_L	1.152	1.00
343_L	347_M	1.147	1.00
484_W	487_T	1.143	1.00
265_R	268_Q	1.140	1.00
137_R	288_T	1.139	1.00
345_E	432_G	1.138	1.00
29_F	35_Q	1.129	1.00
381_L	385_P	1.129	1.00
379_I	508_V	1.128	1.00
313_F	317_T	1.125	1.00
160_D	164_Q	1.124	1.00
436_S	488_H	1.118	1.00
227_L	467_G	1.117	1.00
98_L	165_A	1.113	1.00
59_L	97_V	1.103	1.00
68_E	72_Q	1.099	1.00
120_V	143_L	1.098	1.00
313_F	316_L	1.095	1.00
265_R	478_G	1.094	1.00
184_A	228_L	1.091	1.00
187_P	221_V	1.091	1.00
342_T	345_E	1.090	1.00
12_Y	31_L	1.089	1.00
504_K	507_A	1.085	1.00
358_V	397_L	1.075	1.00
494_K	497_L	1.073	1.00
499_Q	503_D	1.071	1.00
409_L	443_S	1.067	1.00
131_F	210_M	1.062	1.00
98_L	151_L	1.061	1.00
72_Q	75_H	1.059	1.00
29_F	461_A	1.058	1.00
121_S	124_K	1.056	1.00
131_F	134_E	1.055	1.00
107_W	161_I	1.054	1.00
13_Y	83_Y	1.054	1.00
187_P	196_L	1.053	1.00
165_A	217_I	1.052	1.00
268_Q	424_V	1.050	1.00
355_S	358_V	1.045	1.00
347_M	394_F	1.034	1.00
376_P	381_L	1.032	1.00
79_I	83_Y	1.031	1.00
89_A	176_A	1.026	1.00
86_A	468_A	1.023	1.00
62_N	171_I	1.015	1.00
466_V	477_T	1.015	1.00
349_S	434_L	1.010	1.00
119_E	157_H	1.010	1.00
66_A	70_M	1.010	1.00
14_L	468_A	1.007	1.00
401_A	429_G	1.006	1.00
118_R	121_S	1.003	1.00
162_Y	165_A	1.003	1.00
424_V	448_N	1.003	1.00
45_H	57_F	1.001	1.00
403_I	442_V	0.994	1.00
103_G	183_L	0.994	1.00
462_I	477_T	0.993	1.00
265_R	475_A	0.992	1.00
39_G	76_N	0.992	1.00
491_D	495_H	0.990	1.00
43_W	65_L	0.988	1.00
269_T	281_V	0.986	1.00
406_A	442_V	0.975	1.00
14_L	86_A	0.974	1.00
230_V	246_P	0.972	1.00
385_P	392_T	0.969	1.00
86_A	248_V	0.968	1.00
87_V	245_T	0.968	1.00
13_Y	79_I	0.963	1.00
119_E	122_E	0.962	1.00
159_S	163_R	0.962	1.00
85_A	468_A	0.960	1.00
61_K	64_Q	0.957	1.00
148_I	194_G	0.955	1.00
270_A	426_A	0.955	1.00
122_E	125_E	0.950	1.00
161_I	164_Q	0.944	1.00
395_R	434_L	0.940	1.00
115_R	153_W	0.940	1.00
55_M	112_V	0.939	1.00
317_T	358_V	0.939	1.00
49_P	52_P	0.937	1.00
71_R	75_H	0.937	1.00
90_C	456_T	0.935	1.00
208_L	213_L	0.935	1.00
135_V	194_G	0.935	1.00
137_R	199_T	0.932	1.00
98_L	168_I	0.929	1.00
185_V	190_A	0.925	1.00
196_L	200_T	0.925	1.00
74_L	84_I	0.925	1.00
184_A	220_P	0.922	1.00
465_G	470_I	0.922	1.00
265_R	421_S	0.921	1.00
177_Y	183_L	0.918	1.00
15_M	84_I	0.917	1.00
429_G	435_W	0.917	1.00
248_V	468_A	0.917	1.00
151_L	168_I	0.915	1.00
471_F	477_T	0.914	1.00
381_L	393_L	0.912	1.00
444_G	497_L	0.909	1.00
422_S	487_T	0.908	1.00
165_A	168_I	0.907	1.00
104_A	178_M	0.905	1.00
28_I	84_I	0.904	1.00
89_A	175_L	0.904	1.00
26_A	73_A	0.904	1.00
30_D	36_I	0.900	1.00
201_R	223_E	0.894	1.00
187_P	300_V	0.893	1.00
492_P	495_H	0.891	1.00
15_M	28_I	0.891	1.00
154_L	161_I	0.888	1.00
279_Q	409_L	0.888	1.00
284_A	304_M	0.886	1.00
403_I	502_R	0.886	1.00
29_F	458_L	0.884	1.00
96_I	168_I	0.882	1.00
122_E	152_L	0.879	1.00
46_L	49_P	0.877	1.00
291_E	414_D	0.874	1.00
338_I	344_L	0.874	1.00
67_C	71_R	0.874	1.00
476_E	480_R	0.872	1.00
88_S	248_V	0.868	1.00
107_W	154_L	0.867	1.00
181_G	232_S	0.866	1.00
148_I	195_L	0.865	1.00
378_F	397_L	0.864	1.00
41_A	69_C	0.863	1.00
277_W	405_S	0.857	1.00
199_T	288_T	0.857	1.00
235_A	239_C	0.857	1.00
423_L	443_S	0.854	1.00
82_E	242_K	0.849	1.00
202_D	220_P	0.849	1.00
374_A	377_S	0.844	1.00
94_E	192_T	0.844	1.00
99_Y	103_G	0.842	1.00
326_C	390_K	0.841	1.00
120_V	149_P	0.839	1.00
443_S	446_P	0.838	1.00
84_I	245_T	0.836	1.00
187_P	223_E	0.835	1.00
492_P	496_E	0.833	1.00
173_D	185_V	0.831	1.00
222_K	249_V	0.830	1.00
410_Q	414_D	0.827	1.00
169_T	183_L	0.825	1.00
152_L	155_A	0.825	1.00
203_W	218_L	0.824	1.00
500_D	503_D	0.822	1.00
170_M	193_T	0.820	1.00
166_S	216_D	0.819	1.00
19_A	175_L	0.818	1.00
466_V	474_M	0.817	1.00
342_T	346_E	0.817	1.00
430_S	453_K	0.809	1.00
89_A	179_L	0.808	1.00
230_V	243_A	0.806	1.00
257_G	426_A	0.806	1.00
190_A	203_W	0.805	1.00
278_Q	310_I	0.802	1.00
42_E	319_R	0.801	1.00
398_E	438_I	0.796	1.00
348_A	395_R	0.795	1.00
151_L	195_L	0.793	1.00
29_F	452_V	0.792	1.00
233_S	244_G	0.792	1.00
269_T	423_L	0.791	1.00
492_P	497_L	0.791	1.00
85_A	470_I	0.786	1.00
118_R	157_H	0.786	1.00
349_S	437_Q	0.785	1.00
185_V	219_S	0.782	1.00
70_M	74_L	0.781	1.00
106_I	164_Q	0.779	1.00
466_V	473_S	0.777	1.00
61_K	65_L	0.776	1.00
484_W	490_P	0.776	1.00
196_L	201_R	0.773	1.00
38_V	454_E	0.771	1.00
124_K	143_L	0.770	1.00
409_L	413_A	0.769	1.00
261_L	426_A	0.767	1.00
364_D	381_L	0.766	1.00
120_V	144_A	0.764	1.00
411_Q	414_D	0.763	1.00
231_V	239_C	0.762	1.00
41_A	65_L	0.762	1.00
320_W	323_D	0.760	1.00
281_V	412_I	0.759	1.00
35_Q	38_V	0.758	1.00
43_W	57_F	0.758	1.00
507_A	510_Q	0.757	1.00
341_Y	344_L	0.757	1.00
202_D	205_P	0.755	1.00
271_V	405_S	0.754	1.00
496_E	501_S	0.752	1.00
19_A	66_A	0.751	1.00
185_V	221_V	0.751	1.00
121_S	373_H	0.750	1.00
321_F	394_F	0.750	1.00
199_T	285_A	0.749	1.00
448_N	484_W	0.749	1.00
437_Q	491_D	0.748	1.00
309_S	408_N	0.747	1.00
322_R	341_Y	0.747	1.00
319_R	341_Y	0.745	1.00
327_A	338_I	0.744	1.00
365_R	368_F	0.743	1.00
351_V	391_A	0.742	1.00
206_A	210_M	0.740	1.00
425_F	449_I	0.739	1.00
98_L	106_I	0.738	1.00
118_R	156_H	0.736	1.00
398_E	432_G	0.736	1.00
93_R	189_N	0.736	1.00
254_V	278_Q	0.735	1.00
407_C	502_R	0.735	1.00
111_N	276_F	0.734	1.00
16_A	88_S	0.734	1.00
152_L	212_G	0.732	1.00
138_A	197_D	0.732	1.00
209_D	215_A	0.731	1.00
100_N	106_I	0.730	1.00
402_A	435_W	0.730	1.00
271_V	277_W	0.728	1.00
500_D	504_K	0.728	1.00
223_E	302_P	0.724	1.00
425_F	439_L	0.723	1.00
172_S	250_G	0.721	1.00
42_E	322_R	0.719	1.00
406_A	506_Q	0.719	1.00
204_K	207_L	0.718	1.00
60_N	174_W	0.715	1.00
93_R	308_E	0.712	1.00
261_L	270_A	0.712	1.00
241_L	244_G	0.712	1.00
471_F	480_R	0.711	1.00
321_F	393_L	0.709	1.00
87_V	231_V	0.706	1.00
163_R	167_T	0.706	1.00
314_T	401_A	0.706	1.00
430_S	436_S	0.705	1.00
60_N	105_P	0.704	1.00
235_A	244_G	0.701	1.00
223_E	300_V	0.699	1.00
188_S	299_H	0.699	1.00
506_Q	510_Q	0.698	1.00
499_Q	502_R	0.698	1.00
74_L	79_I	0.698	1.00
357_G	379_I	0.698	1.00
135_V	207_L	0.697	1.00
351_V	354_G	0.697	1.00
100_N	166_S	0.696	1.00
283_L	307_A	0.695	1.00
348_A	394_F	0.694	1.00
64_Q	67_C	0.693	1.00
133_N	136_Y	0.692	0.99
349_S	433_K	0.690	0.99
501_S	504_K	0.689	0.99
231_V	245_T	0.684	0.99
24_I	43_W	0.683	0.99
81_P	84_I	0.683	0.99
188_S	251_G	0.682	0.99
356_W	359_M	0.681	0.99
56_E	115_R	0.680	0.99
353_P	497_L	0.679	0.99
358_V	396_A	0.679	0.99
356_W	392_T	0.679	0.99
97_V	108_A	0.678	0.99
231_V	241_L	0.677	0.99
86_A	246_P	0.677	0.99
356_W	396_A	0.677	0.99
197_D	202_D	0.677	0.99
67_C	235_A	0.676	0.99
355_S	395_R	0.676	0.99
27_V	35_Q	0.676	0.99
257_G	456_T	0.675	0.99
68_E	71_R	0.674	0.99
283_L	287_V	0.671	0.99
494_K	499_Q	0.669	0.99
425_F	447_V	0.669	0.99
489_T	492_P	0.668	0.99
176_A	180_S	0.666	0.99
67_C	239_C	0.666	0.99
449_I	485_E	0.665	0.99
423_L	445_L	0.665	0.99
164_Q	167_T	0.663	0.99
345_E	434_L	0.663	0.99
262_G	482_V	0.663	0.99
399_E	438_I	0.662	0.99
475_A	478_G	0.661	0.99
271_V	423_L	0.660	0.99
243_A	246_P	0.660	0.99
103_G	166_S	0.659	0.99
174_W	177_Y	0.656	0.99
101_N	164_Q	0.655	0.99
318_M	345_E	0.655	0.99
21_T	110_A	0.654	0.99
321_F	325_F	0.654	0.99
67_C	178_M	0.652	0.99
366_M	369_K	0.650	0.99
420_P	445_L	0.648	0.99
91_S	189_N	0.646	0.99
263_V	270_A	0.646	0.99
423_L	447_V	0.645	0.99
66_A	69_C	0.645	0.99
109_C	115_R	0.644	0.99
19_A	65_L	0.643	0.99
29_F	457_A	0.642	0.99
70_M	73_A	0.637	0.99
421_S	445_L	0.635	0.99
228_L	249_V	0.635	0.99
227_L	468_A	0.634	0.99
14_L	85_A	0.634	0.99
224_T	250_G	0.633	0.99
70_M	239_C	0.631	0.99
241_L	245_T	0.630	0.99
497_L	501_S	0.630	0.99
503_D	506_Q	0.629	0.99
253_D	275_T	0.628	0.99
67_C	70_M	0.628	0.99
99_Y	177_Y	0.627	0.99
437_Q	488_H	0.627	0.99
263_V	268_Q	0.627	0.99
139_T	207_L	0.626	0.99
31_L	85_A	0.626	0.99
311_S	408_N	0.625	0.99
99_Y	167_T	0.625	0.99
268_Q	421_S	0.624	0.99
183_L	232_S	0.624	0.99
188_S	224_T	0.624	0.99
496_E	499_Q	0.623	0.99
355_S	501_S	0.620	0.99
395_R	438_I	0.620	0.99
230_V	233_S	0.620	0.99
478_G	481_L	0.620	0.99
465_G	469_G	0.619	0.99
209_D	214_R	0.618	0.99
91_S	171_I	0.617	0.99
32_E	480_R	0.616	0.99
146_S	192_T	0.615	0.99
92_M	111_N	0.614	0.99
348_A	351_V	0.613	0.99
286_P	295_R	0.613	0.99
99_Y	174_W	0.613	0.99
446_P	490_P	0.612	0.99
369_K	407_C	0.612	0.99
109_C	154_L	0.611	0.99
143_L	194_G	0.610	0.99
78_G	81_P	0.609	0.99
152_L	211_A	0.608	0.99
239_C	245_T	0.606	0.99
155_A	212_G	0.605	0.99
385_P	389_N	0.604	0.99
444_G	492_P	0.603	0.99
60_N	63_W	0.603	0.99
259_L	301_I	0.602	0.99
141_Q	146_S	0.602	0.99
172_S	189_N	0.602	0.99
277_W	439_L	0.601	0.99
246_P	468_A	0.600	0.99
201_R	300_V	0.597	0.99
477_T	481_L	0.597	0.99
151_L	217_I	0.596	0.99
422_S	445_L	0.596	0.99
152_L	162_Y	0.596	0.99
63_W	235_A	0.595	0.98
433_K	437_Q	0.594	0.98
353_P	395_R	0.593	0.98
59_L	108_A	0.592	0.98
123_L	211_A	0.592	0.98
462_I	466_V	0.591	0.98
452_V	458_L	0.590	0.98
345_E	348_A	0.589	0.98
481_L	484_W	0.588	0.98
182_E	222_K	0.587	0.98
289_D	293_N	0.587	0.98
347_M	351_V	0.586	0.98
162_Y	166_S	0.584	0.98
354_G	385_P	0.583	0.98
369_K	506_Q	0.583	0.98
369_K	509_Y	0.583	0.98
327_A	390_K	0.582	0.98
87_V	247_V	0.581	0.98
280_V	306_Q	0.580	0.98
355_S	399_E	0.579	0.98
235_A	241_L	0.578	0.98
277_W	311_S	0.576	0.98
209_D	212_G	0.576	0.98
117_A	144_A	0.573	0.98
195_L	218_L	0.573	0.98
252_G	255_Q	0.572	0.98
324_A	389_N	0.569	0.98
116_A	149_P	0.569	0.98
96_I	147_A	0.569	0.98
162_Y	212_G	0.569	0.98
35_Q	452_V	0.569	0.98
473_S	477_T	0.566	0.98
258_C	280_V	0.565	0.98
375_A	379_I	0.564	0.98
354_G	395_R	0.564	0.98
115_R	157_H	0.563	0.98
103_G	167_T	0.562	0.98
213_L	218_L	0.561	0.98
471_F	481_L	0.560	0.98
225_G	467_G	0.559	0.98
355_S	392_T	0.559	0.98
14_L	471_F	0.558	0.98
296_V	306_Q	0.557	0.98
316_L	319_R	0.557	0.98
262_G	478_G	0.557	0.98
232_S	244_G	0.556	0.98
474_M	478_G	0.555	0.98
401_A	435_W	0.554	0.98
254_V	272_L	0.554	0.98
123_L	149_P	0.553	0.98
271_V	279_Q	0.553	0.98
38_V	76_N	0.553	0.98
162_Y	214_R	0.552	0.98
319_R	322_R	0.552	0.98
13_Y	82_E	0.551	0.98
193_T	203_W	0.551	0.98
413_A	420_P	0.551	0.98
48_V	55_M	0.551	0.98
499_Q	506_Q	0.549	0.97
273_G	425_F	0.549	0.97
149_P	194_G	0.548	0.97
104_A	164_Q	0.548	0.97
466_V	469_G	0.548	0.97
14_L	31_L	0.548	0.97
135_V	211_A	0.547	0.97
451_V	484_W	0.547	0.97
93_R	192_T	0.545	0.97
34_N	451_V	0.545	0.97
201_R	298_P	0.545	0.97
56_E	107_W	0.543	0.97
98_L	107_W	0.543	0.97
58_D	64_Q	0.538	0.97
345_E	398_E	0.538	0.97
314_T	317_T	0.538	0.97
144_A	372_Y	0.538	0.97
126_L	152_L	0.536	0.97
485_E	490_P	0.534	0.97
34_N	483_R	0.534	0.97
399_E	403_I	0.533	0.97
259_L	462_I	0.533	0.97
466_V	471_F	0.533	0.97
432_G	435_W	0.532	0.97
169_T	177_Y	0.532	0.97
438_I	501_S	0.532	0.97
458_L	462_I	0.531	0.97
318_M	344_L	0.531	0.97
90_C	460_C	0.529	0.97
57_F	110_A	0.529	0.97
268_Q	478_G	0.529	0.97
440_A	447_V	0.528	0.97
272_L	426_A	0.528	0.97
95_G	110_A	0.527	0.97
220_P	226_T	0.527	0.97
207_L	211_A	0.527	0.97
286_P	305_V	0.527	0.97
463_A	474_M	0.526	0.97
21_T	111_N	0.525	0.97
478_G	482_V	0.525	0.97
191_G	298_P	0.525	0.97
344_L	432_G	0.523	0.97
84_I	241_L	0.523	0.97
94_E	276_F	0.523	0.97
457_A	460_C	0.523	0.97
414_D	506_Q	0.523	0.97
430_S	449_I	0.522	0.97
258_C	298_P	0.522	0.97
437_Q	440_A	0.521	0.97
199_T	202_D	0.520	0.97
260_G	455_A	0.520	0.97
341_Y	345_E	0.518	0.96
351_V	395_R	0.518	0.96
281_V	420_P	0.517	0.96
22_G	25_R	0.517	0.96
31_L	465_G	0.517	0.96
12_Y	470_I	0.515	0.96
439_L	443_S	0.514	0.96
59_L	171_I	0.514	0.96
392_T	395_R	0.514	0.96
49_P	54_S	0.513	0.96
187_P	224_T	0.512	0.96
259_L	474_M	0.512	0.96
348_A	398_E	0.511	0.96
156_H	212_G	0.510	0.96
188_S	255_Q	0.509	0.96
357_G	403_I	0.509	0.96
94_E	111_N	0.509	0.96
306_Q	310_I	0.509	0.96
55_M	110_A	0.509	0.96
69_C	73_A	0.509	0.96
224_T	251_G	0.508	0.96
279_Q	408_N	0.508	0.96
403_I	406_A	0.508	0.96
176_A	247_V	0.508	0.96
436_S	449_I	0.508	0.96
96_I	154_L	0.506	0.96
192_T	252_G	0.506	0.96
74_L	80_A	0.505	0.96
338_I	343_L	0.505	0.96
170_M	189_N	0.505	0.96
275_T	316_L	0.505	0.96
444_G	494_K	0.504	0.96
181_G	234_Q	0.503	0.96
344_L	434_L	0.503	0.96
315_G	319_R	0.501	0.96
175_L	179_L	0.501	0.96
54_S	109_C	0.500	0.96
93_R	171_I	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ll3A	2	0.9208	100	0.146	Contact Map
3qdkA	2	0.9604	100	0.164	Contact Map
3hz6A	1	0.9113	100	0.169	Contact Map
2itmA	2	0.8887	100	0.17	Contact Map
3ifrA	2	0.9132	100	0.17	Contact Map
3ezwA	3	0.9189	100	0.18	Contact Map
3l0qA	2	0.9377	100	0.18	Contact Map
3wxlA	2	0.9226	100	0.187	Contact Map
3g25A	3	0.917	100	0.191	Contact Map
3h3nX	3	0.9208	100	0.192	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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